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{"sheet":"ST1","index":1,"n_rows":250,"n_cols":6,"rows_kept":250}
["Abbreviation","Biomarker name","Unit","Group","Subgroup","Derived measure"]
["Acetate","Acetate","mmol/l","Ketone bodies",null,"No"]
["Acetoacetate","Acetoacetate","mmol/l","Ketone bodies",null,"No"]
["Acetone","Acetone","mmol/l","Ketone bodies",null,"No"]
["Ala","Alanine","mmol/l","Amino acids",null,"No"]
["Albumin","Albumin","g/l","Fluid balance",null,"No"]
["ApoA1","Apolipoprotein A1","g/l","Apolipoproteins",null,"No"]
["ApoB","Apolipoprotein B","g/l","Apolipoproteins",null,"No"]
["bOHbutyrate","3-Hydroxybutyrate","mmol/l","Ketone bodies",null,"No"]
["Cholines","Total cholines","mmol/l","Other lipids",null,"No"]
["Citrate","Citrate","mmol/l","Glycolysis related metabolites",null,"No"]
["Clinical_LDL_C","Clinical LDL cholesterol","mmol/l","Cholesterol",null,"No"]
["Creatinine","Creatinine","mmol/l","Fluid balance",null,"No"]
["DHA","Docosahexaenoic acid","mmol/l","Fatty acids",null,"No"]
["Gln","Glutamine","mmol/l","Amino acids",null,"No"]
["Glucose","Glucose","mmol/l","Glycolysis related metabolites",null,"No"]
["Gly","Glycine","mmol/l","Amino acids",null,"No"]
["GlycA","Glycoprotein acetyls","mmol/l","Inflammation",null,"No"]
["HDL_C","HDL cholesterol","mmol/l","Cholesterol",null,"No"]
["HDL_CE","Cholesteryl esters in HDL","mmol/l","Cholesteryl esters",null,"No"]
["HDL_FC","Free cholesterol in HDL","mmol/l","Free cholesterol",null,"No"]
["HDL_L","Total lipids in HDL","mmol/l","Total lipids",null,"No"]
["HDL_P","Concentration of HDL particles","mmol/l","Lipoprotein particle concentrations",null,"No"]
["HDL_PL","Phospholipids in HDL","mmol/l","Phospholipids",null,"No"]
["HDL_size","Average diameter for HDL particles","nm","Lipoprotein particle sizes",null,"No"]
["HDL_TG","Triglycerides in HDL","mmol/l","Triglycerides",null,"No"]
["His","Histidine","mmol/l","Amino acids",null,"No"]
["IDL_C","Cholesterol in IDL","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["IDL_CE","Cholesteryl esters in IDL","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["IDL_FC","Free cholesterol in IDL","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["IDL_L","Total lipids in IDL","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["IDL_P","Concentration of IDL particles","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["IDL_PL","Phospholipids in IDL","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["IDL_TG","Triglycerides in IDL","mmol/l","Lipoprotein subclasses","IDL (average diameter 28.6 nm)","No"]
["Ile","Isoleucine","mmol/l","Amino acids","Branched-chain amino acids","No"]
["L_HDL_C","Cholesterol in large HDL","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_HDL_CE","Cholesteryl esters in large HDL","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_HDL_FC","Free cholesterol in large HDL","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_HDL_L","Total lipids in large HDL","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_HDL_P","Concentration of large HDL particles","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_HDL_PL","Phospholipids in large HDL","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_HDL_TG","Triglycerides in large HDL","mmol/l","Lipoprotein subclasses","Large HDL (average diameter 12.1 nm)","No"]
["L_LDL_C","Cholesterol in large LDL","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_LDL_CE","Cholesteryl esters in large LDL","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_LDL_FC","Free cholesterol in large LDL","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_LDL_L","Total lipids in large LDL","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_LDL_P","Concentration of large LDL particles","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_LDL_PL","Phospholipids in large LDL","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_LDL_TG","Triglycerides in large LDL","mmol/l","Lipoprotein subclasses","Large LDL (average diameter 25.5 nm)","No"]
["L_VLDL_C","Cholesterol in large VLDL","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["L_VLDL_CE","Cholesteryl esters in large VLDL","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["L_VLDL_FC","Free cholesterol in large VLDL","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["L_VLDL_L","Total lipids in large VLDL","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["L_VLDL_P","Concentration of large VLDL particles","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["L_VLDL_PL","Phospholipids in large VLDL","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["L_VLDL_TG","Triglycerides in large VLDL","mmol/l","Lipoprotein subclasses","Large VLDL (average diameter 53.6 nm)","No"]
["LA","Linoleic acid","mmol/l","Fatty acids",null,"No"]
["Lactate","Lactate","mmol/l","Glycolysis related metabolites",null,"No"]
["LDL_C","LDL cholesterol","mmol/l","Cholesterol",null,"No"]
["LDL_CE","Cholesteryl esters in LDL","mmol/l","Cholesteryl esters",null,"No"]
["LDL_FC","Free cholesterol in LDL","mmol/l","Free cholesterol",null,"No"]
["LDL_L","Total lipids in LDL","mmol/l","Total lipids",null,"No"]
["LDL_P","Concentration of LDL particles","mmol/l","Lipoprotein particle concentrations",null,"No"]
["LDL_PL","Phospholipids in LDL","mmol/l","Phospholipids",null,"No"]
["LDL_size","Average diameter for LDL particles","nm","Lipoprotein particle sizes",null,"No"]
["LDL_TG","Triglycerides in LDL","mmol/l","Triglycerides",null,"No"]
["Leu","Leucine","mmol/l","Amino acids","Branched-chain amino acids","No"]
["M_HDL_C","Cholesterol in medium HDL","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_HDL_CE","Cholesteryl esters in medium HDL","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_HDL_FC","Free cholesterol in medium HDL","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_HDL_L","Total lipids in medium HDL","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_HDL_P","Concentration of medium HDL particles","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_HDL_PL","Phospholipids in medium HDL","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_HDL_TG","Triglycerides in medium HDL","mmol/l","Lipoprotein subclasses","Medium HDL (average diameter 10.9 nm)","No"]
["M_LDL_C","Cholesterol in medium LDL","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_LDL_CE","Cholesteryl esters in medium LDL","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_LDL_FC","Free cholesterol in medium LDL","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_LDL_L","Total lipids in medium LDL","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_LDL_P","Concentration of medium LDL particles","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_LDL_PL","Phospholipids in medium LDL","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_LDL_TG","Triglycerides in medium LDL","mmol/l","Lipoprotein subclasses","Medium LDL (average diameter 23 nm)","No"]
["M_VLDL_C","Cholesterol in medium VLDL","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["M_VLDL_CE","Cholesteryl esters in medium VLDL","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["M_VLDL_FC","Free cholesterol in medium VLDL","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["M_VLDL_L","Total lipids in medium VLDL","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["M_VLDL_P","Concentration of medium VLDL particles","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["M_VLDL_PL","Phospholipids in medium VLDL","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["M_VLDL_TG","Triglycerides in medium VLDL","mmol/l","Lipoprotein subclasses","Medium VLDL (average diameter 44.5 nm)","No"]
["MUFA","Monounsaturated fatty acids","mmol/l","Fatty acids",null,"No"]
["Omega_3","Omega-3 fatty acids","mmol/l","Fatty acids",null,"No"]
["Omega_6","Omega-6 fatty acids","mmol/l","Fatty acids",null,"No"]
["Phe","Phenylalanine","mmol/l","Amino acids","Aromatic amino acids","No"]
["Phosphatidylc","Phosphatidylcholines","mmol/l","Other lipids",null,"No"]
["Phosphoglyc","Phosphoglycerides","mmol/l","Other lipids",null,"No"]
["PUFA","Polyunsaturated fatty acids","mmol/l","Fatty acids",null,"No"]
["Pyruvate","Pyruvate","mmol/l","Glycolysis related metabolites",null,"No"]
["S_HDL_C","Cholesterol in small HDL","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_HDL_CE","Cholesteryl esters in small HDL","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_HDL_FC","Free cholesterol in small HDL","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_HDL_L","Total lipids in small HDL","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_HDL_P","Concentration of small HDL particles","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_HDL_PL","Phospholipids in small HDL","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_HDL_TG","Triglycerides in small HDL","mmol/l","Lipoprotein subclasses","Small HDL (average diameter 8.7 nm)","No"]
["S_LDL_C","Cholesterol in small LDL","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_LDL_CE","Cholesteryl esters in small LDL","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_LDL_FC","Free cholesterol in small LDL","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_LDL_L","Total lipids in small LDL","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_LDL_P","Concentration of small LDL particles","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_LDL_PL","Phospholipids in small LDL","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_LDL_TG","Triglycerides in small LDL","mmol/l","Lipoprotein subclasses","Small LDL (average diameter 18.7 nm)","No"]
["S_VLDL_C","Cholesterol in small VLDL","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["S_VLDL_CE","Cholesteryl esters in small VLDL","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["S_VLDL_FC","Free cholesterol in small VLDL","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["S_VLDL_L","Total lipids in small VLDL","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["S_VLDL_P","Concentration of small VLDL particles","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["S_VLDL_PL","Phospholipids in small VLDL","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["S_VLDL_TG","Triglycerides in small VLDL","mmol/l","Lipoprotein subclasses","Small VLDL (average diameter 36.8 nm)","No"]
["SFA","Saturated fatty acids","mmol/l","Fatty acids",null,"No"]
["Sphingomyelins","Sphingomyelins","mmol/l","Other lipids",null,"No"]
["Total_C","Total cholesterol","mmol/l","Cholesterol",null,"No"]
["Total_CE","Total esterified cholesterol","mmol/l","Cholesteryl esters",null,"No"]
["Total_FA","Total fatty acids","mmol/l","Fatty acids",null,"No"]
["Total_FC","Total free cholesterol","mmol/l","Free cholesterol",null,"No"]
["Total_L","Total lipids in lipoprotein particles","mmol/l","Total lipids",null,"No"]
["Total_P","Total concentration of lipoprotein particles","mmol/l","Lipoprotein particle concentrations",null,"No"]
["Total_PL","Total phospholipids in lipoprotein particles","mmol/l","Phospholipids",null,"No"]
["Total_TG","Total triglycerides","mmol/l","Triglycerides",null,"No"]
["Tyr","Tyrosine","mmol/l","Amino acids","Aromatic amino acids","No"]
["Unsaturation","Degree of unsaturation","degree","Fatty acids",null,"No"]
["Val","Valine","mmol/l","Amino acids","Branched-chain amino acids","No"]
["VLDL_C","VLDL cholesterol","mmol/l","Cholesterol",null,"No"]
["VLDL_CE","Cholesteryl esters in VLDL","mmol/l","Cholesteryl esters",null,"No"]
["VLDL_FC","Free cholesterol in VLDL","mmol/l","Free cholesterol",null,"No"]
["VLDL_L","Total lipids in VLDL","mmol/l","Total lipids",null,"No"]
["VLDL_P","Concentration of VLDL particles","mmol/l","Lipoprotein particle concentrations",null,"No"]
["VLDL_PL","Phospholipids in VLDL","mmol/l","Phospholipids",null,"No"]
["VLDL_size","Average diameter for VLDL particles","nm","Lipoprotein particle sizes",null,"No"]
["VLDL_TG","Triglycerides in VLDL","mmol/l","Triglycerides",null,"No"]
["XL_HDL_C","Cholesterol in very large HDL","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_HDL_CE","Cholesteryl esters in very large HDL","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_HDL_FC","Free cholesterol in very large HDL","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_HDL_L","Total lipids in very large HDL","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_HDL_P","Concentration of very large HDL particles","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_HDL_PL","Phospholipids in very large HDL","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_HDL_TG","Triglycerides in very large HDL","mmol/l","Lipoprotein subclasses","Very large HDL (average diameter 14.3 nm)","No"]
["XL_VLDL_C","Cholesterol in very large VLDL","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XL_VLDL_CE","Cholesteryl esters in very large VLDL","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XL_VLDL_FC","Free cholesterol in very large VLDL","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XL_VLDL_L","Total lipids in very large VLDL","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XL_VLDL_P","Concentration of very large VLDL particles","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XL_VLDL_PL","Phospholipids in very large VLDL","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XL_VLDL_TG","Triglycerides in very large VLDL","mmol/l","Lipoprotein subclasses","Very large VLDL (average diameter 64 nm)","No"]
["XS_VLDL_C","Cholesterol in very small VLDL","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XS_VLDL_CE","Cholesteryl esters in very small VLDL","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XS_VLDL_FC","Free cholesterol in very small VLDL","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XS_VLDL_L","Total lipids in very small VLDL","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XS_VLDL_P","Concentration of very small VLDL particles","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XS_VLDL_PL","Phospholipids in very small VLDL","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XS_VLDL_TG","Triglycerides in very small VLDL","mmol/l","Lipoprotein subclasses","Very small VLDL (average diameter 31.3 nm)","No"]
["XXL_VLDL_C","Cholesterol in chylomicrons and extremely large VLDL","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["XXL_VLDL_CE","Cholesteryl esters in chylomicrons and extremely large VLDL","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["XXL_VLDL_FC","Free cholesterol in chylomicrons and extremely large VLDL","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["XXL_VLDL_L","Total lipids in chylomicrons and extremely large VLDL","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["XXL_VLDL_P","Concentration of chylomicrons and extremely large VLDL particles","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["XXL_VLDL_PL","Phospholipids in chylomicrons and extremely large VLDL","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["XXL_VLDL_TG","Triglycerides in chylomicrons and extremely large VLDL","mmol/l","Lipoprotein subclasses","Chylomicrons and extremely large VLDL (particle diameters from 75 nm upwards)","No"]
["ApoB_by_ApoA1","Ratio of apolipoprotein B to apolipoprotein A1","ratio","Apolipoproteins",null,"Yes"]
["DHA_pct","Ratio of docosahexaenoic acid to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["IDL_C_pct","Cholesterol to total lipids ratio in IDL","%","Relative lipoprotein lipid concentrations","IDL ratios","Yes"]
["IDL_CE_pct","Cholesteryl esters to total lipids ratio in IDL","%","Relative lipoprotein lipid concentrations","IDL ratios","Yes"]
["IDL_FC_pct","Free cholesterol to total lipids ratio in IDL","%","Relative lipoprotein lipid concentrations","IDL ratios","Yes"]
["IDL_PL_pct","Phospholipids to total lipids ratio in IDL","%","Relative lipoprotein lipid concentrations","IDL ratios","Yes"]
["IDL_TG_pct","Triglycerides to total lipids ratio in IDL","%","Relative lipoprotein lipid concentrations","IDL ratios","Yes"]
["L_HDL_C_pct","Cholesterol to total lipids ratio in large HDL","%","Relative lipoprotein lipid concentrations","Large HDL ratios","Yes"]
["L_HDL_CE_pct","Cholesteryl esters to total lipids ratio in large HDL","%","Relative lipoprotein lipid concentrations","Large HDL ratios","Yes"]
["L_HDL_FC_pct","Free cholesterol to total lipids ratio in large HDL","%","Relative lipoprotein lipid concentrations","Large HDL ratios","Yes"]
["L_HDL_PL_pct","Phospholipids to total lipids ratio in large HDL","%","Relative lipoprotein lipid concentrations","Large HDL ratios","Yes"]
["L_HDL_TG_pct","Triglycerides to total lipids ratio in large HDL","%","Relative lipoprotein lipid concentrations","Large HDL ratios","Yes"]
["L_LDL_C_pct","Cholesterol to total lipids ratio in large LDL","%","Relative lipoprotein lipid concentrations","Large LDL ratios","Yes"]
["L_LDL_CE_pct","Cholesteryl esters to total lipids ratio in large LDL","%","Relative lipoprotein lipid concentrations","Large LDL ratios","Yes"]
["L_LDL_FC_pct","Free cholesterol to total lipids ratio in large LDL","%","Relative lipoprotein lipid concentrations","Large LDL ratios","Yes"]
["L_LDL_PL_pct","Phospholipids to total lipids ratio in large LDL","%","Relative lipoprotein lipid concentrations","Large LDL ratios","Yes"]
["L_LDL_TG_pct","Triglycerides to total lipids ratio in large LDL","%","Relative lipoprotein lipid concentrations","Large LDL ratios","Yes"]
["L_VLDL_C_pct","Cholesterol to total lipids ratio in large VLDL","%","Relative lipoprotein lipid concentrations","Large VLDL ratios","Yes"]
["L_VLDL_CE_pct","Cholesteryl esters to total lipids ratio in large VLDL","%","Relative lipoprotein lipid concentrations","Large VLDL ratios","Yes"]
["L_VLDL_FC_pct","Free cholesterol to total lipids ratio in large VLDL","%","Relative lipoprotein lipid concentrations","Large VLDL ratios","Yes"]
["L_VLDL_PL_pct","Phospholipids to total lipids ratio in large VLDL","%","Relative lipoprotein lipid concentrations","Large VLDL ratios","Yes"]
["L_VLDL_TG_pct","Triglycerides to total lipids ratio in large VLDL","%","Relative lipoprotein lipid concentrations","Large VLDL ratios","Yes"]
["LA_pct","Ratio of linoleic acid to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["M_HDL_C_pct","Cholesterol to total lipids ratio in medium HDL","%","Relative lipoprotein lipid concentrations","Medium HDL ratios","Yes"]
["M_HDL_CE_pct","Cholesteryl esters to total lipids ratio in medium HDL","%","Relative lipoprotein lipid concentrations","Medium HDL ratios","Yes"]
["M_HDL_FC_pct","Free cholesterol to total lipids ratio in medium HDL","%","Relative lipoprotein lipid concentrations","Medium HDL ratios","Yes"]
["M_HDL_PL_pct","Phospholipids to total lipids ratio in medium HDL","%","Relative lipoprotein lipid concentrations","Medium HDL ratios","Yes"]
["M_HDL_TG_pct","Triglycerides to total lipids ratio in medium HDL","%","Relative lipoprotein lipid concentrations","Medium HDL ratios","Yes"]
["M_LDL_C_pct","Cholesterol to total lipids ratio in medium LDL","%","Relative lipoprotein lipid concentrations","Medium LDL ratios","Yes"]
["M_LDL_CE_pct","Cholesteryl esters to total lipids ratio in medium LDL","%","Relative lipoprotein lipid concentrations","Medium LDL ratios","Yes"]
["M_LDL_FC_pct","Free cholesterol to total lipids ratio in medium LDL","%","Relative lipoprotein lipid concentrations","Medium LDL ratios","Yes"]
["M_LDL_PL_pct","Phospholipids to total lipids ratio in medium LDL","%","Relative lipoprotein lipid concentrations","Medium LDL ratios","Yes"]
["M_LDL_TG_pct","Triglycerides to total lipids ratio in medium LDL","%","Relative lipoprotein lipid concentrations","Medium LDL ratios","Yes"]
["M_VLDL_C_pct","Cholesterol to total lipids ratio in medium VLDL","%","Relative lipoprotein lipid concentrations","Medium VLDL ratios","Yes"]
["M_VLDL_CE_pct","Cholesteryl esters to total lipids ratio in medium VLDL","%","Relative lipoprotein lipid concentrations","Medium VLDL ratios","Yes"]
["M_VLDL_FC_pct","Free cholesterol to total lipids ratio in medium VLDL","%","Relative lipoprotein lipid concentrations","Medium VLDL ratios","Yes"]
["M_VLDL_PL_pct","Phospholipids to total lipids ratio in medium VLDL","%","Relative lipoprotein lipid concentrations","Medium VLDL ratios","Yes"]
["M_VLDL_TG_pct","Triglycerides to total lipids ratio in medium VLDL","%","Relative lipoprotein lipid concentrations","Medium VLDL ratios","Yes"]
["MUFA_pct","Ratio of monounsaturated fatty acids to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["non_HDL_C","Total cholesterol minus HDL-C","mmol/l","Cholesterol",null,"Yes"]
["Omega_3_pct","Ratio of omega-3 fatty acids to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["Omega_6_by_Omega_3","Ratio of omega-6 fatty acids to omega-3 fatty acids","ratio","Fatty acids","Fatty acid ratios","Yes"]
["Omega_6_pct","Ratio of omega-6 fatty acids to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["PUFA_by_MUFA","Ratio of polyunsaturated fatty acids to monounsaturated fatty acids","ratio","Fatty acids","Fatty acid ratios","Yes"]
["PUFA_pct","Ratio of polyunsaturated fatty acids to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["Remnant_C","Remnant cholesterol (non-HDL, non-LDL -cholesterol)","mmol/l","Cholesterol",null,"Yes"]
["S_HDL_C_pct","Cholesterol to total lipids ratio in small HDL","%","Relative lipoprotein lipid concentrations","Small HDL ratios","Yes"]
["S_HDL_CE_pct","Cholesteryl esters to total lipids ratio in small HDL","%","Relative lipoprotein lipid concentrations","Small HDL ratios","Yes"]
["S_HDL_FC_pct","Free cholesterol to total lipids ratio in small HDL","%","Relative lipoprotein lipid concentrations","Small HDL ratios","Yes"]
["S_HDL_PL_pct","Phospholipids to total lipids ratio in small HDL","%","Relative lipoprotein lipid concentrations","Small HDL ratios","Yes"]
["S_HDL_TG_pct","Triglycerides to total lipids ratio in small HDL","%","Relative lipoprotein lipid concentrations","Small HDL ratios","Yes"]
["S_LDL_C_pct","Cholesterol to total lipids ratio in small LDL","%","Relative lipoprotein lipid concentrations","Small LDL ratios","Yes"]
["S_LDL_CE_pct","Cholesteryl esters to total lipids ratio in small LDL","%","Relative lipoprotein lipid concentrations","Small LDL ratios","Yes"]
["S_LDL_FC_pct","Free cholesterol to total lipids ratio in small LDL","%","Relative lipoprotein lipid concentrations","Small LDL ratios","Yes"]
["S_LDL_PL_pct","Phospholipids to total lipids ratio in small LDL","%","Relative lipoprotein lipid concentrations","Small LDL ratios","Yes"]
["S_LDL_TG_pct","Triglycerides to total lipids ratio in small LDL","%","Relative lipoprotein lipid concentrations","Small LDL ratios","Yes"]
["S_VLDL_C_pct","Cholesterol to total lipids ratio in small VLDL","%","Relative lipoprotein lipid concentrations","Small VLDL ratios","Yes"]
["S_VLDL_CE_pct","Cholesteryl esters to total lipids ratio in small VLDL","%","Relative lipoprotein lipid concentrations","Small VLDL ratios","Yes"]
["S_VLDL_FC_pct","Free cholesterol to total lipids ratio in small VLDL","%","Relative lipoprotein lipid concentrations","Small VLDL ratios","Yes"]
["S_VLDL_PL_pct","Phospholipids to total lipids ratio in small VLDL","%","Relative lipoprotein lipid concentrations","Small VLDL ratios","Yes"]
["S_VLDL_TG_pct","Triglycerides to total lipids ratio in small VLDL","%","Relative lipoprotein lipid concentrations","Small VLDL ratios","Yes"]
["SFA_pct","Ratio of saturated fatty acids to total fatty acids","%","Fatty acids","Fatty acid ratios","Yes"]
["TG_by_PG","Ratio of triglycerides to phosphoglycerides","ratio","Other lipids",null,"Yes"]
["Total_BCAA","Total concentration of branched-chain amino acids (leucine + isoleucine + valine)","mmol/l","Amino acids","Branched-chain amino acids","Yes"]
["XL_HDL_C_pct","Cholesterol to total lipids ratio in very large HDL","%","Relative lipoprotein lipid concentrations","Very large HDL ratios","Yes"]
["XL_HDL_CE_pct","Cholesteryl esters to total lipids ratio in very large HDL","%","Relative lipoprotein lipid concentrations","Very large HDL ratios","Yes"]
["XL_HDL_FC_pct","Free cholesterol to total lipids ratio in very large HDL","%","Relative lipoprotein lipid concentrations","Very large HDL ratios","Yes"]
["XL_HDL_PL_pct","Phospholipids to total lipids ratio in very large HDL","%","Relative lipoprotein lipid concentrations","Very large HDL ratios","Yes"]
["XL_HDL_TG_pct","Triglycerides to total lipids ratio in very large HDL","%","Relative lipoprotein lipid concentrations","Very large HDL ratios","Yes"]
["XL_VLDL_C_pct","Cholesterol to total lipids ratio in very large VLDL","%","Relative lipoprotein lipid concentrations","Very large VLDL ratios","Yes"]
["XL_VLDL_CE_pct","Cholesteryl esters to total lipids ratio in very large VLDL","%","Relative lipoprotein lipid concentrations","Very large VLDL ratios","Yes"]
["XL_VLDL_FC_pct","Free cholesterol to total lipids ratio in very large VLDL","%","Relative lipoprotein lipid concentrations","Very large VLDL ratios","Yes"]
["XL_VLDL_PL_pct","Phospholipids to total lipids ratio in very large VLDL","%","Relative lipoprotein lipid concentrations","Very large VLDL ratios","Yes"]
["XL_VLDL_TG_pct","Triglycerides to total lipids ratio in very large VLDL","%","Relative lipoprotein lipid concentrations","Very large VLDL ratios","Yes"]
["XS_VLDL_C_pct","Cholesterol to total lipids ratio in very small VLDL","%","Relative lipoprotein lipid concentrations","Very small VLDL ratios","Yes"]
["XS_VLDL_CE_pct","Cholesteryl esters to total lipids ratio in very small VLDL","%","Relative lipoprotein lipid concentrations","Very small VLDL ratios","Yes"]
["XS_VLDL_FC_pct","Free cholesterol to total lipids ratio in very small VLDL","%","Relative lipoprotein lipid concentrations","Very small VLDL ratios","Yes"]
["XS_VLDL_PL_pct","Phospholipids to total lipids ratio in very small VLDL","%","Relative lipoprotein lipid concentrations","Very small VLDL ratios","Yes"]
["XS_VLDL_TG_pct","Triglycerides to total lipids ratio in very small VLDL","%","Relative lipoprotein lipid concentrations","Very small VLDL ratios","Yes"]
["XXL_VLDL_C_pct","Cholesterol to total lipids ratio in chylomicrons and extremely large VLDL","%","Relative lipoprotein lipid concentrations","Chylomicrons and extremely large VLDL ratios","Yes"]
["XXL_VLDL_CE_pct","Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL","%","Relative lipoprotein lipid concentrations","Chylomicrons and extremely large VLDL ratios","Yes"]
["XXL_VLDL_FC_pct","Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL","%","Relative lipoprotein lipid concentrations","Chylomicrons and extremely large VLDL ratios","Yes"]
["XXL_VLDL_PL_pct","Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL","%","Relative lipoprotein lipid concentrations","Chylomicrons and extremely large VLDL ratios","Yes"]
["XXL_VLDL_TG_pct","Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL","%","Relative lipoprotein lipid concentrations","Chylomicrons and extremely large VLDL ratios","Yes"]

{"sheet":"ST2","index":2,"n_rows":53,"n_cols":13,"rows_kept":53,"merged":[[0,0,1,0],[0,1,1,1],[0,2,1,2],[0,3,1,3],[0,4,1,4],[0,6,1,6],[0,7,1,7],[0,8,1,8],[0,9,1,9],[0,10,1,10],[0,11,1,11],[0,12,1,12],[2,0,3,0],[2,1,3,1],[2,2,3,2],[2,3,3,3],[2,4,3,4],[2,6,3,6],[2,7,3,7],[2,8,3,8],[2,9,3,9],[2,10,3,10],[2,11,3,11],[2,12,3,12],[4,0,5,0],[4,1,5,1],[4,2,5,2],[4,3,5,3],[4,4,5,4],[4,6,5,6],[4,7,5,7],[4,8,5,8],[4,9,5,9],[4,10,5,10],[4,11,5,11],[4,12,5,12],[6,0,7,0],[6,1,7,1],[6,2,7,2],[6,3,7,3],[6,4,7,4],[6,6,7,6],[6,7,7,7],[6,8,7,8],[6,9,7,9],[6,10,7,10],[6,11,7,11],[6,12,7,12],[8,0,9,0],[8,1,9,1],[8,2,9,2],[8,3,9,3],[8,4,9,4],[8,6,9,6],[8,7,9,7],[8,8,9,8],[8,9,9,9],[8,10,9,10],[8,11,9,11],[8,12,9,12],[10,0,11,0],[10,1,11,1],[10,2,11,2],[10,3,11,3],[10,4,11,4],[10,6,11,6],[10,7,11,7],[10,8,11,8],[10,9,11,9],[10,10,11,10],[10,11,11,11],[10,12,11,12],[12,0,15,0],[12,1,33,1],[12,2,33,2],[12,4,33,4],[12,6,33,6],[12,7,33,7],[12,8,33,8],[12,9,33,9],[12,10,33,10],[12,11,33,11],[12,12,33,12],[13,5,15,5],[16,0,18,0],[17,5,18,5],[19,0,21,0],[20,5,21,5],[22,0,24,0],[23,5,24,5],[25,0,27,0],[26,5,27,5],[28,0,31,0],[28,5,29,5],[30,5,31,5],[32,0,33,0],[32,3,33,3],[34,0,35,0],[34,1,49,1],[34,2,49,2],[34,3,35,3],[34,4,49,4],[34,6,49,6],[34,7,49,7],[34,8,49,8],[34,9,49,9],[34,10,49,10],[34,11,49,11],[34,12,49,12],[36,0,37,0],[36,3,37,3],[38,0,39,0],[38,3,39,3],[40,0,41,0],[40,3,41,3],[42,0,43,0],[42,3,43,3],[44,0,45,0],[44,3,45,3],[46,0,47,0],[46,3,47,3],[48,0,49,0],[48,3,49,3]]}
["Primary outcome","Study/consortium","Publication year","Case definition","N studies","N participants","Ancestry","Imputation reference panel","Control for population structure","Model","Units","PMID","Data access"]
[{"$nulls":5},"(cases / controls)"]
["Coronary artery disease","CARDIoGRAM-plusC4D",2015,"Inclusive CAD diagnosis (e.g., myocardial infarction, acute coronary syndrome, chronic stable angina or coronary stenosis of >50%)",48,{"v":184305,"d":"184,305"},"European (77%)","1000G phase 1 v3","Double genomic inflation factor correction","A","log odds",26343387,"http://www.cardiogramplusc4d.org/data-downloads/ "]
[{"$nulls":5},"(60,801 / 123,504)"]
["Ischemic stroke","MEGASTROKE",2018,"Case ascertainment varied across studies",17,{"v":446696,"d":"446,696"},"European","1000G phase 1","Genomic inflation factor correction","A","log odds",29531354,"http://www.megastroke.org/"]
[{"$nulls":5},"(40,585 / 406,111)"]
["Heart failure","HERMES",2020,"Clinical diagnosis of heart failure of any aetiology with no inclusion criteria based on left ventricular ejection fraction",26,{"v":977323,"d":"977,323"},"European","1000G (60%), HRC (35%) or others (5%)","Principal components of ancestry","A","log odds",31919418,"http://kp4cd.org/datasets/mi"]
[{"$nulls":5},"(47,309 / 930,014)"]
["Atrial fibrillation","Nielsen et al",2018,"ICD-10 code I48 and/or ICD-9 code 427.3",6,{"v":1030836,"d":"1,030,836"},"European","HRC","Principal components of ancestry, genomic control or mixed models","A","log odds",30061737,"http://csg.sph.umich.edu/willer/public/afib2018/"]
[{"$nulls":5},"(60,620 / 970,216)"]
["Aortic aneurysm1","Jones et al",2017,"Abdominal aortic aneurysm: Infra-renal aortic diameter ≥30 mm",6,{"v":104830,"d":"104,830"},"European","1000G","Genomic inflation factor correction","A","log odds",27899403,"From correspondence"]
[{"$nulls":5},"(4,972 / 99,858)"]
["Coronary artery disease","UK Biobank","NA","ICD10: I20.X-I25.X",1,{"v":464620,"d":"464,620"},"European (British)","HRC","Generalized linear mixed models (BOLT-LMM)","A","log odds","NA","https://www.ukbiobank.ac.uk/register-apply/"]
[{"$nulls":3},"ICD9: 410.X-412.X, 414.0, 414.8, 414.9, 429.79",null,"(37,501 / 427,119)  "]
[{"$nulls":3},"Self-report: non-cancer illness code (data field: 20002) "]
[{"$nulls":3},"Self-report: health condition diagnosed by doctor (data field: 6150)"]
["Ischemic stroke",null,null,"ICD10: I63.X",null,{"v":464620,"d":"464,620"}]
[{"$nulls":3},"ICD9: 433.X, 434.X",null,"(4,764 / 459,856)"]
[{"$nulls":3},"Self-report: non-cancer illness code (data field: 20002) "]
["Hemorrhagic stroke",null,null,"ICD10: I60.X, I61.X",null,{"v":464620,"d":"464,620"}]
[{"$nulls":3},"ICD9: 430.X, 431.X",null,"(2,472 / 462,148)"]
[{"$nulls":3},"Self-report: non-cancer illness code (data field: 20002) "]
["Peripheral artery disease  ",null,null,"ICD10: I73.8, I73.9",null,{"v":464620,"d":"464,620"}]
[{"$nulls":3},"ICD9: 443.8, 443.9",null,"(4,513 / 460,107)"]
[{"$nulls":3},"Self-report: non-cancer illness code (data field: 20002) "]
["Aortic aneurysm",null,null,"ICD10: I71.X",null,{"v":464620,"d":"464,620"}]
[{"$nulls":3},"ICD9: 441.X",null,"(2,248 / 462,372)"]
[{"$nulls":3},"Self-report: non-cancer illness code (data field: 20002) "]
["Venous thromboembolism",null,null,"ICD10: I26.X, I80.1, I80.2, I81.X, I82.0",null,{"v":464620,"d":"464,620"}]
[{"$nulls":3},"ICD9: 415.1, 451.1, 452.X, 453.X"]
[{"$nulls":3},"Self-report: non-cancer illness code (data field: 20002) ",null,"(18,371 / 446,249)"]
[{"$nulls":3},"Self-report: health condition diagnosed by doctor (data field: 6150)"]
["Aortic valve stenosis",null,null,"ICD10: I35.0, I35.2",null,{"v":464620,"d":"464,620"}]
[{"$nulls":5},"(2,844 / 461,776)"]
["Coronary artery disease","FinnGen (release 4)",2020,"ICD10: I20.X-I25.X",1,{"v":176899,"d":"176,899"},"European (Finish)","Population-specific imputation reference panel (i.e. SISu v3)2","Generalized linear mixed model (SAIGE)","A","log odds","NA","https://www.finngen.fi/en/access_results"]
[{"$nulls":5},"(25,366 / 151,533)"]
["Ischemic stroke",null,null,"ICD10: I63.X (excl. 163.6), I64",null,{"v":172332,"d":"172,332"}]
[{"$nulls":5},"(8,046 / 164,286)"]
["Hemorrhagic stroke",null,null,"ICD10 codes: I60.X, I61.X",null,{"v":167126,"d":"167,126"}]
[{"$nulls":5},"(2,086 / 165,040)"]
["Heart failure",null,null,"ICD10 codes: I11.0, 13.0, I13.2, I50.X",null,{"v":176445,"d":"176,445"}]
[{"$nulls":5},"(17,387 / 159,058)"]
["Atrial fibrillation",null,null,"ICD10 codes: I48.X",null,{"v":114539,"d":"114,539"}]
[{"$nulls":5},"(17,325 / 97,214)"]
["Peripheral artery disease",null,null,"ICD10 codes: E10.5, E11.5, E12.5, E13.5, E14.5, I70.2, I73.9",null,{"v":173166,"d":"173,166"}]
[{"$nulls":5},"(5,323 / 167,843)"]
["Aortic aneurysm",null,null,"ICD10 codes: I71.1-I71.9",null,{"v":169762,"d":"169,762"}]
[{"$nulls":5},"(1,919 / 167,843)"]
["Venous thromboembolism",null,null,"ICD10 codes: I26.X, I80.X, O87.1, O88.2 ",null,{"v":176899,"d":"176,899"}]
[{"$nulls":5},"(6,913 / 169,986)"]
["1000G: 1000 Genomes; HRC: Haplotype Reference Consortium; CAD: coronary artery disease; ICD: International Classication of Diseases"]
["1 Log odds per effect allele (and corresponding standard error) was approximated from z-statistics provided by the original GWAS using the equation: beta = sqrt( z^2 / (z^2 + ncase) / 2 / (maf * (1-maf)) * pi^2/3 ) * sign(z)"]
["2 SISu v3 consists of 3,775 high coverage (30x) WGS Finnish individuals from six cohorts. More information: https://finngen.gitbook.io/documentation/methods/genotype-imputation/sisu-reference-panel"]

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[]
[null,"DHA",null,"Total omega-3",null,"Linoleic acid",null,"Total fatty acids",null,"Tryglycerides",null,"LDL-cholesterol",null,"Apolipoprotein B"]
[null,"rG","rG (SE)","rG","rG (SE)","rG","rG (SE)","rG","rG (SE)","rG","rG (SE)","rG","rG (SE)","rG","rG (SE)"]
["DHA",{"$nulls":6},{"v":0.3021,"d":"0.30"},{"v":0.0774,"d":"0.08"},{"v":-0.007,"d":"-0.01"},{"v":0.0793,"d":"0.08"},{"v":0.5674,"d":"0.57"},{"v":0.081,"d":"0.08"},{"v":0.4365,"d":"0.44"},{"v":0.0705,"d":"0.07"}]
["Total omega-3",{"v":0.8489,"d":"0.85"},{"v":0.0233,"d":"0.02"},{"$nulls":4},{"v":0.6892,"d":"0.69"},{"v":0.0538,"d":"0.05"},{"v":0.4933,"d":"0.49"},{"v":0.0683,"d":"0.07"},{"v":0.505,"d":"0.51"},{"v":0.0959,"d":"0.10"},{"v":0.6312,"d":"0.63"},{"v":0.0997,"d":"0.10"}]
["Linoleic acid",{"v":0.3918,"d":"0.39"},{"v":0.0696,"d":"0.07"},{"v":0.6109,"d":"0.61"},{"v":0.0676,"d":"0.07"},null,null,{"v":0.8178,"d":"0.82"},{"v":0.0442,"d":"0.04"},{"v":0.6043,"d":"0.60"},{"v":0.0623,"d":"0.06"},{"v":0.6798,"d":"0.68"},{"v":0.0903,"d":"0.09"},{"v":0.7948,"d":"0.79"},{"v":0.0681,"d":"0.07"}]
["Total omega-6",{"v":0.4605,"d":"0.46"},{"v":0.0626,"d":"0.06"},{"v":0.6825,"d":"0.68"},{"v":0.0558,"d":"0.06"},{"v":0.9492,"d":"0.95"},{"v":0.0317,"d":"0.03"},{"v":0.8965,"d":"0.90"},{"v":0.0199,"d":"0.02"},{"v":0.6125,"d":"0.61"},{"v":0.0647,"d":"0.06"},{"v":0.7558,"d":"0.76"},{"v":0.0628,"d":"0.06"},{"v":0.8429,"d":"0.84"},{"v":0.0458,"d":"0.05"}]

{"sheet":"ST4A","index":4,"n_rows":784,"n_cols":23,"rows_kept":784}
["ensg","symbol","chr","start","end","strand","type","entrezID","HUGO","pLI","ncRVIS","posMapSNPs","posMapMaxCADD","eqtlMapSNPs","eqtlMapminP","eqtlMapminQ","eqtlMapts","eqtlDirection","ciMap","ciMapts","minGwasP","IndSigSNPs","GenomicLocus"]
["ENSG00000143126","CELSR2",1,109792641,109818372,1,"protein_coding",1952,"CELSR2",0.999999199832348,0.807304437,23,18.47,27,{"v":9.42742e-34,"d":"9.43E-34"},{"v":2.20583e-27,"d":"2.21E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen",{"v":7.3e-20,"d":"7.30E-20"},"rs6657811;1:109809343_CT_C;rs4970834;rs11102967;rs629301;rs657420;rs629301:rs629301;rs4970834:rs11102967:rs657420:rs6657811:1:109809343_CT_C:rs4970834",3]
["ENSG00000134222","PSRC1",1,109822178,109825808,-1,"protein_coding",84722,"PSRC1",{"v":1.74717788563073e-06,"d":"1.75E-06"},-0.208880013,24,18.47,27,{"v":1.0541E-37,"d":"1.05E-37"},{"v":1.834e-30,"d":"1.83E-30"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":7.3e-20,"d":"7.30E-20"},"rs4970834;rs11102967;rs629301;rs657420;rs6657811",3]
["ENSG00000134243","SORT1",1,109852192,109940573,-1,"protein_coding",6272,"SORT1",0.999926560036891,-1.346190944,0,0,20,{"v":3.08634e-54,"d":"3.09E-54"},{"v":3.21918e-45,"d":"3.22E-45"},"GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.3e-20,"d":"7.30E-20"},"rs6657811;rs4970834;rs11102967;rs629301;rs6657811:1:109809343_CT_C:rs629301:rs629301;rs4970834:rs11102967:rs657420:rs4970834",3]
["ENSG00000143028","SYPL2",1,110009180,110024759,1,"protein_coding",284612,"SYPL2",0.0167710987562036,0.437866135,0,0,21,{"v":5.67264E-10,"d":"5.67E-10"},{"v":1.41445e-54,"d":"1.41E-54"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver","-","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7.3e-20,"d":"7.30E-20"},"rs6657811;rs4970834;rs629301;rs11102967;rs657420;rs657420:rs6657811:1:109809343_CT_C:rs4970834:rs11102967:rs629301;rs4970834:rs629301",3]
["ENSG00000162650","ATXN7L2",1,110026101,110035426,1,"protein_coding",127002,"ATXN7L2",0.718954812432385,"NA",0,0,14,{"v":5.83014e-07,"d":"5.83E-07"},{"v":6.65426e-17,"d":"6.65E-17"},"GTEx/v8/Liver","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7.3e-20,"d":"7.30E-20"},"rs11102967;rs629301;rs4970834;rs657420;rs657420:rs6657811:1:109809343_CT_C:rs4970834:rs11102967:rs629301;rs4970834:rs629301",3]
["ENSG00000174151","CYB561D1",1,110036674,110045554,1,"protein_coding",284613,"CYB561D1",0.0158304191038284,-0.395994268,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7.3e-20,"d":"7.30E-20"},"rs657420:rs6657811:1:109809343_CT_C:rs4970834:rs11102967:rs629301;rs4970834:rs629301",3]
["ENSG00000031698","SARS",1,109756540,109780791,1,"protein_coding",6301,"SARS",0.999150650957633,-0.332037527,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-19,"d":"1.20E-19"},"rs657420:rs629301:rs629301;rs4970834:rs11102967",3]
["ENSG00000162607","USP1",1,62901968,62917475,1,"protein_coding",7398,"USP1",0.993180568281562,-1.542076225,50,18.26,7,{"v":1.97043E-7,"d":"1.97E-07"},4.32786E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8E-19,"d":"2.80E-19"},"rs638714;rs778356958;rs371562288;rs1183851;rs10889363;rs536629310;rs7512480;rs6688417:rs638714;rs371562288:rs638714:rs10889363;rs536629310:rs638714;rs371562288:rs1183851:rs638714;rs778356958:rs778356958:rs10889363:rs6688417:1:63045366_GA_G",2]
["ENSG00000116641","DOCK7",1,62920399,63153969,-1,"protein_coding",85440,"DOCK7",0.771361085896655,"NA",277,18.64,401,{"v":1.09201E-20,"d":"1.09E-20"},{"v":9.93875E-16,"d":"9.94E-16"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.8E-19,"d":"2.80E-19"},"rs638714;rs778356958;rs371562288;rs10889363;rs536629310;rs1183851;rs55853774;1:63045366_GA_G;1:63134595_CA_C;1:63149883_TA_T;rs6688417;rs7512480;rs10889363:rs778356958:rs638714;rs371562288:rs638714:rs10889363;rs536629310:rs638714;rs371562288:rs1183851:1:63045366_GA_G",2]
["ENSG00000132855","ANGPTL3",1,63063158,63071830,1,"protein_coding",27329,"ANGPTL3",{"v":2.12015609401708e-07,"d":"2.12E-07"},-0.803837249,15,12.12,15,{"v":1.13102e-05,"d":"1.13E-05"},0.0421505,"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8E-19,"d":"2.80E-19"},"rs638714;rs371562288;rs778356958;rs371562288:rs638714:rs10889363;rs536629310:rs638714;rs371562288:rs1183851:rs638714;rs778356958:rs778356958:rs10889363:rs371562288:rs536629310:rs55853774:1:63134595_CA_C:1:63149883_TA_T:rs6688417:rs7512480;rs6688417:rs7512480",2]
["ENSG00000269624","AL138847.1",1,63073437,63075249,1,"protein_coding","NA","NA","NA","NA",11,12.12,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8E-19,"d":"2.80E-19"},"rs638714;rs371562288;rs1183851;rs778356958;rs371562288:rs638714:rs10889363;rs536629310:rs638714;rs371562288:rs1183851:rs638714;rs778356958:rs778356958:rs10889363:rs371562288:rs536629310:rs55853774:1:63134595_CA_C:1:63149883_TA_T:rs6688417:rs7512480;rs6688417:rs7512480",2]
["ENSG00000125703","ATG4C",1,63249806,63331184,1,"protein_coding",84938,"ATG4C",{"v":3.32761781234443e-09,"d":"3.33E-09"},-0.809376853,92,17.7,66,{"v":6.89586e-06,"d":"6.90E-06"},0.00836476,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8E-19,"d":"2.80E-19"},"rs7512480;rs6688417;rs638714:rs638714;rs778356958;rs371562288:rs1183851:rs638714;rs371562288:rs10889363;rs536629310:rs638714;rs778356958:rs371562288:rs536629310:1:63045366_GA_G:rs55853774:rs778356958:rs10889363",2]
["ENSG00000203965","EFCAB7",1,63989043,64038364,1,"protein_coding",84455,"EFCAB7",{"v":1.67071925383672e-12,"d":"1.67E-12"},-0.503488032,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8E-19,"d":"2.80E-19"},"rs638714:rs638714;rs778356958;rs371562288:rs1183851:rs638714;rs371562288:rs638714;rs778356958:rs10889363;rs536629310:rs7512480;rs6688417:rs6688417:rs7512480:1:63045366_GA_G:rs778356958:rs10889363:rs55853774",2]
["ENSG00000134709","HOOK1",1,60280458,60342050,1,"protein_coding",51361,"HOOK1",{"v":4.15670073195207e-05,"d":"4.16E-05"},-0.06279745,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":5.3e-19,"d":"5.30E-19"},"rs638714;rs371562288:rs1183851:rs10889363;rs536629310:rs638714;rs778356958;rs371562288:rs638714",2]
["ENSG00000116652","DLEU2L",1,64014588,64015405,1,"protein_coding",79469,"DLEU2L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.3e-19,"d":"5.30E-19"},"rs638714;rs778356958;rs371562288:rs638714:rs10889363;rs536629310:rs638714;rs371562288:rs1183851:rs7512480;rs6688417:rs6688417:rs7512480:rs371562288:rs536629310:rs638714;rs778356958:rs778356958:rs10889363",2]
["ENSG00000162437","RAVER2",1,65210778,65298915,1,"protein_coding",55225,"RAVER2",{"v":1.85996394365043E-6,"d":"1.86E-06"},-0.746777186,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":5.8E-19,"d":"5.80E-19"},"rs638714;rs371562288:rs638714:rs371562288:rs536629310:rs10889363;rs536629310:rs7512480;rs6688417:rs6688417:rs7512480:1:63045366_GA_G:rs638714;rs778356958:rs1183851:rs778356958:rs10889363",2]
["ENSG00000116209","TMEM59",1,54497347,54519177,-1,"protein_coding",9528,"TMEM59",{"v":2.23025067852854E-7,"d":"2.23E-07"},0.206649282,0,0,1,{"v":2.03947E-5,"d":"2.04E-05"},1.96452E-3,"GTEx/v8/Artery_Aorta","+","No","NA",{"v":2.4e-13,"d":"2.40E-13"},"rs11591147",1]
["ENSG00000169174","PCSK9",1,55505221,55530525,1,"protein_coding",255738,"PCSK9",{"v":1.02507611210468E-10,"d":"1.03E-10"},0.264270736,1,15.41,0,"NA","NA","NA","NA","No","NA",{"v":2.4e-13,"d":"2.40E-13"},"rs11591147",1]
["ENSG00000088035","ALG6",1,63833261,63904233,1,"protein_coding",29929,"ALG6",0.0553676261725129,-0.307102505,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.4e-10,"d":"1.40E-10"},"rs7512480;rs6688417:rs6688417:rs7512480",2]
["ENSG00000181754","AMIGO1",1,110046797,110052360,-1,"protein_coding",57463,"AMIGO1",0.888492588974354,-0.212526248,0,0,7,{"v":1.84657E-16,"d":"1.85E-16"},{"v":3.62238e-97,"d":"3.62E-97"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":2e-10,"d":"2.00E-10"},"rs657420;rs6657811:1:109809343_CT_C",3]
["ENSG00000156097","GPR61",1,110082494,110091028,1,"protein_coding",83873,"GPR61",0.801488898268086,-0.586870154,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2e-10,"d":"2.00E-10"},"rs6657811:1:109809343_CT_C",3]
["ENSG00000121957","GPSM2",1,109417972,109477167,1,"protein_coding",29899,"GPSM2",{"v":2.9412972070079e-10,"d":"2.94E-10"},0.141117521,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway",{"v":1.5e-08,"d":"1.50E-08"},"rs6657811",3]
["ENSG00000085433","WDR47",1,109512836,109584850,-1,"protein_coding",22911,"WDR47",0.90566161819711,-0.351230971,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Fetal_Cortex",{"v":1.5e-08,"d":"1.50E-08"},"rs6657811:rs657420",3]
["ENSG00000179902","C1orf194",1,109648573,109656479,-1,"protein_coding",127003,"C1orf194",{"v":2.50029511352176e-07,"d":"2.50E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway",{"v":1.5e-08,"d":"1.50E-08"},"rs6657811",3]
["ENSG00000116299","KIAA1324",1,109656301,109749401,1,"protein_coding",57535,"KIAA1324",{"v":2.14864520738644E-8,"d":"2.15E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway",{"v":1.5e-08,"d":"1.50E-08"},"rs6657811",3]
["ENSG00000221986","MYBPHL",1,109834987,109849663,-1,"protein_coding",343263,"MYBPHL",0.00461844098878081,0.281706372,8,11.65,0,"NA","NA","NA","NA","Yes","EP_links_oneway",{"v":1.5e-08,"d":"1.50E-08"},"rs657420;rs6657811",3]
["ENSG00000069248","NUP133",1,229577045,229644103,-1,"protein_coding",55746,"NUP133",0.0662324196154904,-0.412790867,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.3e-08,"d":"3.30E-08"},"rs11122450",4]
["ENSG00000135801","TAF5L",1,229728858,229761794,-1,"protein_coding",27097,"TAF5L",0.985849776766725,-0.172748825,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs11122450",4]
["ENSG00000135763","URB2",1,229761981,229795946,1,"protein_coding",9816,"URB2",{"v":3.33649047524477e-11,"d":"3.34E-11"},0.023857228,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs11122450",4]
["ENSG00000143641","GALNT2",1,230193536,230417870,1,"protein_coding",2590,"GALNT2",0.881985612838068,4.223663186,30,11.93,2,{"v":4.23554e-05,"d":"4.24E-05"},{"v":1.659E-7,"d":"1.66E-07"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","IMR90:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs11122450",4]
["ENSG00000154429","CCSAP",1,229456758,229479041,-1,"protein_coding",126731,"CCSAP",0.11178307102521,-1.423602825,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.5e-08,"d":"3.50E-08"},"rs11122450",4]
["ENSG00000135776","ABCB10",1,229652329,229694442,-1,"protein_coding",23456,"ABCB10",{"v":7.9478594059038e-06,"d":"7.95E-06"},-0.017192186,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.5e-08,"d":"3.50E-08"},"rs11122450",4]
["ENSG00000215717","TMEM167B",1,109632425,109639556,1,"protein_coding",56900,"TMEM167B",0.632476718728509,-0.038371693,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.9E-6,"d":"1.90E-06"},"rs657420",3]
["ENSG00000143106","PSMA5",1,109941653,109969062,-1,"protein_coding",5686,"PSMA5",0.974255885097096,-1.084093805,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.9E-6,"d":"1.90E-06"},"rs657420",3]
["ENSG00000168765","GSTM4",1,110198703,110208118,1,"protein_coding",2948,"GSTM4",0.000917344712640999,0.373951732,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.9E-6,"d":"1.90E-06"},"rs657420",3]
["ENSG00000138085","ATRAID",2,27434895,27440046,1,"protein_coding",51374,"ATRAID",0.00791394898030435,"NA",0,0,143,{"v":2.77951e-11,"d":"2.78E-11"},{"v":5.3045e-26,"d":"5.30E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs1260326;rs780110:rs1260326",6]
["ENSG00000115234","SNX17",2,27593389,27599995,1,"protein_coding",9784,"SNX17",0.686180301198043,-0.681943317,23,18.47,177,{"v":1.17643e-13,"d":"1.18E-13"},{"v":2.00912e-09,"d":"2.01E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs1260326;2:27739880_CT_C;rs4665985;rs77200710;2:28003616_TA_T;rs67798437;rs780110:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T:rs1728918:rs67086575:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000115241","PPM1G",2,27604061,27632554,-1,"protein_coding",5496,"PPM1G",0.996010385533881,-0.482626092,49,12.85,181,{"v":1.94157e-13,"d":"1.94E-13"},{"v":1.67809e-09,"d":"1.68E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs1260326;rs1728918;2:27739880_CT_C;rs67798437;rs780110:rs1260326:rs67798437:rs77200710;rs4665985:rs77200710:rs67086575:rs77200710;2:28003616_TA_T",6]
["ENSG00000115216","NRBP1",2,27650657,27665126,1,"protein_coding",29959,"NRBP1",0.999548511025196,-1.389706011,42,14.1,222,{"v":1.48664E-19,"d":"1.49E-19"},{"v":1.00894E-14,"d":"1.01E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs1260326;rs1728918;2:27739880_CT_C;rs67798437;rs77200710;rs4665985;rs67086575;2:28003616_TA_T;rs780110:rs1260326:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T:rs67086575:rs4665985:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000157992","KRTCAP3",2,27665233,27669348,1,"protein_coding",200634,"KRTCAP3",0.0445235342133754,"NA",24,9.832,172,{"v":6.96594E-10,"d":"6.97E-10"},{"v":4.42568e-06,"d":"4.43E-06"},"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs1260326;2:27739880_CT_C;rs67798437;rs780110:rs1728918:rs77200710;rs4665985:rs67798437:rs77200710:rs77200710;2:28003616_TA_T:rs1260326:rs67086575:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000138002","IFT172",2,27667238,27712656,-1,"protein_coding",26160,"IFT172",{"v":2.29011817971014E-18,"d":"2.29E-18"},-0.505254909,67,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs67086575;rs780110:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T:rs1260326:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000115226","FNDC4",2,27714750,27718112,-1,"protein_coding",64838,"FNDC4",0.759219015798597,"NA",22,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs780110:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T:rs1260326:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000084734","GCKR",2,27719709,27746554,1,"protein_coding",2646,"GCKR",{"v":3.58392509874806e-16,"d":"3.58E-16"},-0.155697744,54,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs780110;rs1260326;2:27739880_CT_C;rs4665985;rs67798437;rs77200710;rs780110:rs67798437:rs77200710;rs4665985:rs1260326:rs77200710:rs77200710;2:28003616_TA_T:rs1728918:rs67086575:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000233438","AC109829.1",2,27760253,27790011,1,"protein_coding","NA","NA","NA","NA",40,9.736,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs1260326;2:27739880_CT_C;rs780110;rs4665985;rs67798437;rs77200710;2:27786252_CTTTTTTTTTT_C;rs780110:rs1260326:rs67086575:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T",6]
["ENSG00000221843","C2orf16",2,27799389,27805588,1,"protein_coding",84226,"C2orf16",{"v":3.91661992667067e-17,"d":"3.92E-17"},-0.329746802,15,14.88,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs77200710;rs4665985;rs67798437;rs780110:rs1260326:rs67086575:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T",6]
["ENSG00000243943","ZNF512",2,27805897,27858041,1,"protein_coding",84450,"ZNF512",0.949146986047491,-1.279253328,42,14.88,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs67798437;rs77200710;rs4665985;2:28003616_TA_T;rs780110:rs77200710;rs4665985:rs67798437:rs1260326:rs67086575:rs1728918:rs77200710:rs77200710;2:28003616_TA_T:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000176714","CCDC121",2,27848506,27851879,-1,"protein_coding",79635,"CCDC121",{"v":9.72713578876563e-05,"d":"9.73E-05"},-0.266319334,10,14.13,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs67798437;rs77200710;rs4665985;rs780110:rs67086575:rs1260326:rs67798437:rs77200710;rs4665985:rs77200710:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C:rs77200710;2:28003616_TA_T",6]
["ENSG00000198522","GPN1",2,27851114,27874375,1,"protein_coding",11321,"GPN1",0.0049035919998219,-0.238154635,8,14.13,216,{"v":7.93394e-08,"d":"7.93E-08"},0.000297808,"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs67798437;rs77200710;2:28003616_TA_T;rs4665985;rs780110;rs1260326;2:27739880_CT_C;rs780110:rs67086575:rs1260326:rs67798437:rs77200710;rs4665985:rs77200710:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:2:27786252_CTTTTTTTTTT_C:rs77200710",6]
["ENSG00000119760","SUPT7L",2,27873679,27886676,-1,"protein_coding",9913,"SUPT7L",0.833193338587633,-0.966218532,3,4.564,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":2.5e-30,"d":"2.50E-30"},"rs77200710;2:28003616_TA_T;rs780110:rs1260326:rs1728918:rs67086575:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710",6]
["ENSG00000163798","SLC4A1AP",2,27886338,27917840,1,"protein_coding",22950,"SLC4A1AP",{"v":7.73999085415032e-07,"d":"7.74E-07"},-0.546764453,4,15.03,31,{"v":1.50619E-6,"d":"1.51E-06"},{"v":8.71618E-6,"d":"8.72E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":2.5e-30,"d":"2.50E-30"},"rs77200710;2:28003616_TA_T;rs67798437;rs780110;rs780110:rs1260326:rs1728918:rs67086575:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710",6]
["ENSG00000163803","PLB1",2,28680012,28866654,1,"protein_coding",151056,"PLB1",{"v":1.9931529274349E-56,"d":"1.99E-56"},0.411383907,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-30,"d":"2.50E-30"},"rs67798437:rs77200710;rs4665985:rs77200710;2:28003616_TA_T:2:28003616_TA_T:rs77200710:rs780110:rs67086575:2:27786252_CTTTTTTTTTT_C:rs1260326:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs4665985",6]
["ENSG00000268656","AC110084.1",2,27998851,28009186,-1,"protein_coding","NA","NA","NA","NA",2,8.25,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9E-27,"d":"1.90E-27"},"2:28003616_TA_T;rs780110:rs1260326;2:27739880_CT_C:rs77200710;2:28003616_TA_T:2:28003616_TA_T",6]
["ENSG00000084764","MAPRE3",2,27193480,27250064,1,"protein_coding",22924,"MAPRE3",0.799864407370243,-0.767319281,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000119777","TMEM214",2,27255778,27264563,1,"protein_coding",54867,"TMEM214",0.00116735534958103,-0.517227915,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000084693","AGBL5",2,27265232,27293490,1,"protein_coding",60509,"AGBL5",0.0206948513459665,-0.378650928,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000228474","OST4",2,27293340,27294641,-1,"protein_coding",100128731,"OST4","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000138080","EMILIN1",2,27301435,27309271,1,"protein_coding",11117,"EMILIN1",0.00521656081419512,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000138030","KHK",2,27309615,27323640,1,"protein_coding",3795,"KHK",{"v":5.36079485314004e-05,"d":"5.36E-05"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000138028","CGREF1",2,27321757,27341995,-1,"protein_coding",10669,"CGREF1",{"v":5.50290788195318E-8,"d":"5.50E-08"},0.491986309,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000143994","ABHD1",2,27346682,27353680,1,"protein_coding",84696,"ABHD1",{"v":1.06027288753589e-21,"d":"1.06E-21"},-0.251069432,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000138073","PREB",2,27353624,27357543,-1,"protein_coding",10113,"PREB",0.0018983627682706,-0.154458724,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000138074","SLC5A6",2,27422455,27435826,-1,"protein_coding",8884,"SLC5A6",0.571968337581082,-0.400099261,0,0,149,{"v":3.91291e-09,"d":"3.91E-09"},{"v":1.13875E-17,"d":"1.14E-17"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4e-26,"d":"1.40E-26"},"rs780110;rs1260326;2:27739880_CT_C;rs780110:rs1260326",6]
["ENSG00000084774","CAD",2,27440258,27466811,1,"protein_coding",790,"CAD",0.999999701880854,-0.710759294,0,0,142,{"v":3.06886e-10,"d":"3.07E-10"},{"v":9.08683e-20,"d":"9.09E-20"},"GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs780110;rs1260326;rs780110:rs1260326",6]
["ENSG00000115194","SLC30A3",2,27476552,27498685,-1,"protein_coding",7781,"SLC30A3",0.64608387237045,-0.660463482,0,0,1,{"v":2.22523e-09,"d":"2.23E-09"},{"v":7.40729e-24,"d":"7.41E-24"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-26,"d":"1.40E-26"},"rs67086575;rs780110:rs1260326",6]
["ENSG00000163793","DNAJC5G",2,27498289,27504367,1,"protein_coding",285126,"DNAJC5G",3.97478941010456E-3,-0.706717729,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000138100","TRIM54",2,27505260,27530307,1,"protein_coding",57159,"TRIM54",{"v":8.24707898322991E-7,"d":"8.25E-07"},-1.053267254,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-26,"d":"1.40E-26"},"rs780110:rs1260326",6]
["ENSG00000115204","MPV17",2,27532360,27548547,-1,"protein_coding",4358,"MPV17",{"v":1.10286841801097E-8,"d":"1.10E-08"},-0.205368529,4,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4e-26,"d":"1.40E-26"},"rs780110;rs780110:rs1260326:rs67798437:rs77200710;rs4665985",6]
["ENSG00000115207","GTF3C2",2,27548716,27579868,-1,"protein_coding",2976,"GTF3C2",0.999786435918561,-0.837016421,30,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs780110;rs780110:rs1260326:rs77200710;2:28003616_TA_T:rs67798437:rs77200710;rs4665985:rs77200710:rs1728918:rs67086575:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000115211","EIF2B4",2,27587219,27593353,-1,"protein_coding",8890,"EIF2B4",0.832609528731968,-0.214235303,24,18.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs780110;rs1260326;rs780110:rs67798437:rs77200710;rs4665985:rs77200710:rs77200710;2:28003616_TA_T:rs1728918:rs67086575:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000163795","ZNF513",2,27600098,27603657,-1,"protein_coding",130557,"ZNF513",0.940738428263313,"NA",17,18.47,26,{"v":3.61445e-05,"d":"3.61E-05"},0.0342333,"GTEx/v8/Artery_Aorta","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-26,"d":"1.40E-26"},"rs780110;rs1260326;rs780110:rs1728918:rs1260326:rs67798437:rs77200710;rs4665985:rs77200710:rs67086575:rs77200710;2:28003616_TA_T",6]
["ENSG00000075426","FOSL2",2,28615315,28640179,1,"protein_coding",2355,"FOSL2",0.925334261981773,-2.20415963,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Bladder:Left_Ventricle:Liver:Lung:Pancreas:Psoas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4e-26,"d":"1.40E-26"},"rs77200710;2:28003616_TA_T:2:28003616_TA_T:rs780110:rs1260326:rs67086575:rs77200710;rs4665985:rs67798437:rs77200710",6]
["ENSG00000118960","HS1BP3",2,20760208,20850849,-1,"protein_coding",64342,"HS1BP3",0.000353324886507251,2.114325929,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.4e-24,"d":"7.40E-24"},"rs531819:rs562338;rs531819:rs60403635:rs562338;rs531819;rs7419374:2:21277213_GCT_G:rs562338:rs562338;rs34601365;rs380240:rs375330151:rs71435594:rs12618122:rs562338;rs7419374:rs562338;rs380240:rs34601365:rs368220458",5]
["ENSG00000143869","GDF7",2,20866424,20873418,1,"protein_coding",151449,"GDF7",0.778067351749562,0.171953881,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.4e-24,"d":"7.40E-24"},"rs531819:rs562338;rs531819:rs60403635:rs562338;rs531819;rs7419374:2:21277213_GCT_G:rs562338:rs562338;rs34601365;rs380240:rs375330151:rs71435594:rs12618122:rs562338;rs7419374:rs562338;rs380240:rs34601365:rs368220458",5]
["ENSG00000118961","C2orf43",2,20883788,21022882,-1,"protein_coding",60526,"C2orf43",0.00064748477489379,-0.605069014,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.4e-24,"d":"7.40E-24"},"rs562338;rs531819;rs7419374:rs562338:rs60403635:rs562338;rs34601365;rs380240:rs375330151:rs71435594:rs531819:rs562338;rs531819:2:21277213_GCT_G:rs12618122:rs562338;rs7419374:rs562338;rs380240:rs34601365:rs368220458",5]
["ENSG00000084674","APOB",2,21224301,21266945,-1,"protein_coding",338,"APOB",{"v":5.49085163436995e-16,"d":"5.49E-16"},-0.34689194,13,8.1,273,{"v":1.23445E-15,"d":"1.23E-15"},{"v":1.88901e-24,"d":"1.89E-24"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Liver:Mesendoderm:hESC",{"v":7.4e-24,"d":"7.40E-24"},"rs531819;rs562338;rs60403635;rs7419374;rs34601365;rs380240;rs10177017;rs312045;rs71435594;rs12618122;rs7571647;rs1848922;rs7419374:rs562338:rs60403635:rs562338;rs380240:rs375330151:rs71435594:rs12618122:rs562338;rs7419374:rs562338;rs380240:rs34601365:rs368220458",5]
["ENSG00000218819","TDRD15",2,21346789,21366144,1,"protein_coding",100129278,"TDRD15","NA","NA",16,8.625,1,{"v":3.84105e-05,"d":"3.84E-05"},{"v":4.5811e-10,"d":"4.58E-10"},"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.4e-24,"d":"7.40E-24"},"rs562338;rs7419374;rs34601365;rs380240;rs375330151;rs12618122;rs531819;rs7419374:rs562338:rs60403635:rs562338;rs380240:rs375330151:rs71435594:rs562338;rs7419374:rs34601365:rs12618122:rs368220458:rs531819:rs562338;rs531819:2:21277213_GCT_G",5]
["ENSG00000119771","KLHL29",2,23608088,23931481,1,"protein_coding",114818,"KLHL29","NA",-0.399831988,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":7.4e-24,"d":"7.40E-24"},"rs531819:rs562338;rs531819:rs60403635:rs562338;rs531819;rs7419374:2:21277213_GCT_G:rs562338;rs7419374:rs562338;rs34601365;rs380240:rs34601365:rs12618122:rs368220458:rs375330151:rs562338:rs71435594:rs380240:rs380240;rs10177017:rs7419374:rs380240;rs7571647;rs1848922;rs10177017:rs7571647:rs10177017:rs312045:rs380240;rs312045;rs10177017:rs1848922:rs7571647;rs10177017",5]
["ENSG00000171094","ALK",2,29415640,30144432,-1,"protein_coding",238,"ALK",0.522362516846561,-0.624899803,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.5E-22,"d":"1.50E-22"},"rs77200710;rs4665985:rs67798437:rs77200710:2:27786252_CTTTTTTTTTT_C",6]
["ENSG00000213639","PPP1CB",2,28974506,29025806,1,"protein_coding",5500,"PPP1CB",0.997194974203565,0.001839166,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-21,"d":"1.90E-21"},"rs780110:rs77200710;2:28003616_TA_T:2:28003616_TA_T:rs67086575:rs77200710;rs4665985:rs67798437:rs77200710",6]
["ENSG00000163806","SPDYA",2,29005383,29073477,1,"protein_coding",245711,"SPDYA",0.166884223990281,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-21,"d":"1.90E-21"},"rs77200710;rs4665985:rs67798437:rs77200710:rs77200710;2:28003616_TA_T:2:28003616_TA_T",6]
["ENSG00000171103","TRMT61B",2,29072687,29093167,-1,"protein_coding",55006,"TRMT61B",{"v":4.00751770882134e-06,"d":"4.01E-06"},-0.602142186,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-21,"d":"1.90E-21"},"rs780110:rs77200710;2:28003616_TA_T:rs77200710;rs4665985:rs67798437",6]
["ENSG00000205334","AC074091.13",2,27928653,27938599,-1,"protein_coding",100129995,"LINC01460","NA","NA",4,12.09,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-14,"d":"4.10E-14"},"rs77200710;2:28003616_TA_T",6]
["ENSG00000243147","MRPL33",2,27994584,28210954,1,"protein_coding",9553,"MRPL33",0.749164756585824,-0.22012956,6,14.77,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.1e-14,"d":"4.10E-14"},"2:28003616_TA_T;rs77200710;2:28003616_TA_T:2:28003616_TA_T",6]
["ENSG00000171174","RBKS",2,28004231,28113965,-1,"protein_coding",64080,"RBKS",{"v":1.93197572918752E-5,"d":"1.93E-05"},-0.689745423,5,14.77,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-14,"d":"4.10E-14"},"2:28003616_TA_T;2:28003616_TA_T:rs77200710",6]
["ENSG00000158019","BRE",2,28112808,28561768,1,"protein_coding",9577,"BRE",0.279976282823241,"NA",1,5.473,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-14,"d":"4.10E-14"},"2:28003616_TA_T;2:28003616_TA_T:rs77200710",6]
["ENSG00000163811","WDR43",2,29117509,29171088,1,"protein_coding",23160,"WDR43",0.998942440488972,1.455113129,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.1e-14,"d":"4.10E-14"},"rs77200710;2:28003616_TA_T",6]
["ENSG00000157856","DRC1",2,26624784,26679579,1,"protein_coding",92749,"DRC1",{"v":1.30453003302834e-10,"d":"1.30E-10"},0.353225525,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.1e-11,"d":"1.10E-11"},"rs780110",6]
["ENSG00000213699","SLC35F6",2,26987152,27004099,1,"protein_coding",54978,"SLC35F6",0.0161307579092324,-0.353050684,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.1e-11,"d":"1.10E-11"},"rs780110",6]
["ENSG00000115163","CENPA",2,26987157,27023935,1,"protein_coding",1058,"CENPA",0.139975206060218,-0.80838147,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.1e-11,"d":"1.10E-11"},"rs780110",6]
["ENSG00000076003","MCM6",2,136597196,136633996,-1,"protein_coding",4175,"MCM6",0.998482019514362,0.155094687,40,13.46,199,{"v":2.72387e-21,"d":"2.72E-21"},{"v":7.54241e-16,"d":"7.54E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-11,"d":"2.20E-11"},"rs11681659;rs11399929;rs80261410;rs11399929:rs11681659;rs11399929:rs80261410:rs11681659;rs80261410:rs11681659",7]
["ENSG00000115866","DARS",2,136664247,136743670,-1,"protein_coding",1615,"DARS",6.1199920887983E-4,0.123876255,14,16.38,185,{"v":2.65762E-8,"d":"2.66E-08"},{"v":3.69417e-08,"d":"3.69E-08"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":2.2e-11,"d":"2.20E-11"},"rs11681659;rs11399929;rs80261410;rs11399929:rs11399929:rs11681659;rs80261410:rs80261410:rs11681659",7]
["ENSG00000121966","CXCR4",2,136871919,136875735,-1,"protein_coding",7852,"CXCR4",0.427450979947767,-0.284617205,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.2e-11,"d":"2.20E-11"},"rs11681659;rs11399929:rs11681659;rs80261410:rs80261410:rs11399929:rs11681659",7]
["ENSG00000144224","UBXN4",2,136499189,136542625,1,"protein_coding",23190,"UBXN4",0.974205695161288,-0.658500963,51,20.7,166,{"v":6.82361e-08,"d":"6.82E-08"},{"v":6.12378E-6,"d":"6.12E-06"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs11399929;rs11681659;rs80261410;rs11399929:rs11399929:rs11681659",7]
["ENSG00000144229","THSD7B",2,137523115,138435287,1,"protein_coding",80731,"THSD7B",{"v":5.65285413355626e-06,"d":"5.65E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":2.5e-10,"d":"2.50E-10"},"rs11681659;rs11399929:rs11399929:rs11681659;rs80261410:rs80261410",7]
["ENSG00000150540","HNMT",2,138721590,138773930,1,"protein_coding",3176,"HNMT",0.0967293826850996,0.562236353,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.5e-10,"d":"2.50E-10"},"rs11681659;rs11399929:rs11681659;rs80261410:rs80261410",7]
["ENSG00000144227","NXPH2",2,139428342,139537918,-1,"protein_coding",11249,"NXPH2",0.798014407186903,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.5e-10,"d":"2.50E-10"},"rs11681659;rs11399929:rs11399929:rs11681659;rs80261410:rs80261410",7]
["ENSG00000143970","ASXL2",2,25956622,26101385,-1,"protein_coding",55252,"ASXL2",0.992738818422806,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.7e-09,"d":"2.70E-09"},"rs780110",6]
["ENSG00000268412","AC013449.1",2,26251074,26251481,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.7e-09,"d":"2.70E-09"},"rs780110",6]
["ENSG00000084733","RAB10",2,26256976,26360323,1,"protein_coding",10890,"RAB10",0.944404791408518,-0.583904709,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.7e-09,"d":"2.70E-09"},"rs780110",6]
["ENSG00000173567","GPR113",2,26531041,26569685,-1,"protein_coding",165082,"GPR113",{"v":1.48528745876047E-10,"d":"1.49E-10"},0.291622367,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.7e-09,"d":"2.70E-09"},"rs780110",6]
["ENSG00000186143","C2orf53",2,27359723,27362278,-1,"protein_coding",339779,"C2orf53",{"v":1.54927478958821e-09,"d":"1.55E-09"},0.62491408,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex",{"v":2.7e-09,"d":"2.70E-09"},"rs780110",6]
["ENSG00000163792","TCF23",2,27371872,27376378,1,"protein_coding",150921,"TCF23",0.000503312310069814,-0.683069484,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.7e-09,"d":"2.70E-09"},"rs780110",6]
["ENSG00000152128","TMEM163",2,135213330,135476570,-1,"protein_coding",81615,"TMEM163",0.0672624651374226,0.397258421,0,0,52,{"v":4.73418e-09,"d":"4.73E-09"},{"v":1.60223E-14,"d":"1.60E-14"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","No","NA",{"v":5.8e-09,"d":"5.80E-09"},"rs11681659;rs11399929",7]
["ENSG00000048991","R3HDM1",2,136289025,136482840,1,"protein_coding",23518,"R3HDM1",0.00602513988409452,-0.983617194,40,21,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":5.8e-09,"d":"5.80E-09"},"rs11681659;rs11399929",7]
["ENSG00000082258","CCNT2",2,135675805,135716912,1,"protein_coding",905,"CCNT2",0.49810408150126,-1.291148908,0,0,74,{"v":1.31669E-6,"d":"1.32E-06"},{"v":6.72446e-18,"d":"6.72E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","+","No","NA",{"v":1.7E-8,"d":"1.70E-08"},"rs11399929;rs11681659",7]
["ENSG00000115839","RAB3GAP1",2,135809835,135933964,1,"protein_coding",22930,"RAB3GAP1",{"v":3.66101381631237E-5,"d":"3.66E-05"},-0.439175216,6,17.62,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7E-8,"d":"1.70E-08"},"rs11681659;rs11399929;rs11399929:rs11681659",7]
["ENSG00000121988","ZRANB3",2,135894486,136288806,-1,"protein_coding",84083,"ZRANB3",{"v":7.42639986547535e-15,"d":"7.43E-15"},-0.510649767,16,17.62,99,{"v":8.34853e-06,"d":"8.35E-06"},{"v":4.0053e-06,"d":"4.01E-06"},"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.7E-8,"d":"1.70E-08"},"rs11681659;rs11399929",7]
["ENSG00000115850","LCT",2,136545410,136594750,-1,"protein_coding",3938,"LCT",0.0642550168201587,0.129442028,45,20.7,0,"NA","NA","NA","NA","No","NA",{"v":2.3e-08,"d":"2.30E-08"},"rs11399929;rs11681659",7]
["ENSG00000063660","GPC1",2,241375088,241407493,1,"protein_coding",2817,"GPC1",0.109569938244377,1.271141184,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.5e-08,"d":"2.50E-08"},"rs13424225",8]
["ENSG00000218416","AC110619.2",2,241388732,241396131,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.5e-08,"d":"2.50E-08"},"rs13424225",8]
["ENSG00000176601","MAP3K19",2,135722061,135805038,-1,"protein_coding",80122,"MAP3K19",{"v":3.69884742626308e-14,"d":"3.70E-14"},0.1252064,1,1.436,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.1e-08,"d":"4.10E-08"},"rs11399929;rs11399929:rs11681659",7]
["ENSG00000183840","GPR39",2,133174147,133404132,1,"protein_coding",2863,"GPR39",{"v":1.54608229502499E-12,"d":"1.55E-12"},-0.108893739,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6E-7,"d":"1.60E-07"},"rs11399929",7]
["ENSG00000065802","ASB1",2,239335383,239360891,1,"protein_coding",51665,"ASB1",0.350835778789251,1.495309247,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.7E-7,"d":"3.70E-07"},"rs13424225",8]
["ENSG00000178602","OTOS",2,241078446,241083979,-1,"protein_coding",150677,"OTOS",{"v":2.78890336245965e-07,"d":"2.79E-07"},1.218670238,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm",{"v":3.7E-7,"d":"3.70E-07"},"rs13424225",8]
["ENSG00000144504","ANKMY1",2,241418839,241508626,-1,"protein_coding",51281,"ANKMY1",{"v":7.81266990643975e-14,"d":"7.81E-14"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.7E-7,"d":"3.70E-07"},"rs13424225",8]
["ENSG00000188542","DUSP28",2,241499471,241503431,1,"protein_coding",285193,"DUSP28",0.23221694539441,0.425047153,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.7E-7,"d":"3.70E-07"},"rs13424225",8]
["ENSG00000142327","RNPEPL1",2,241505221,241520789,1,"protein_coding",57140,"RNPEPL1",0.0279016170372594,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.7E-7,"d":"3.70E-07"},"rs13424225",8]
["ENSG00000226894","TMPRSS11BNL",4,69054242,69083798,-1,"protein_coding",401136,"TMPRSS11BNL",0.315776901388964,0.704294788,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.4E-16,"d":"5.40E-16"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342:rs4860987",9]
["ENSG00000185873","TMPRSS11B",4,69092371,69111438,-1,"protein_coding",132724,"TMPRSS11B",{"v":1.68050228934566e-11,"d":"1.68E-11"},0.053188955,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.4E-16,"d":"5.40E-16"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342:rs4860987",9]
["ENSG00000197888","UGT2B17",4,69402902,69434245,-1,"protein_coding",7367,"UGT2B17",0.0102556056990611,0.903832175,57,9.889,104,{"v":2.78097e-19,"d":"2.78E-19"},{"v":5.32642E-14,"d":"5.33E-14"},"GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Liver",{"v":5.4E-16,"d":"5.40E-16"},"rs9884390;rs4860987;rs386675580;rs2603187;rs2123886;rs1349849;rs35307342;rs4860987:rs35307342",9]
["ENSG00000109181","UGT2B10",4,69681711,69696914,1,"protein_coding",7365,"UGT2B10",{"v":5.50615564451229e-15,"d":"5.51E-15"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.4E-16,"d":"5.40E-16"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342:rs4860987",9]
["ENSG00000171234","UGT2B7",4,69917081,69978705,1,"protein_coding",7364,"UGT2B7",{"v":3.49679084556951e-08,"d":"3.50E-08"},0.82500636,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.4E-16,"d":"5.40E-16"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342:rs4860987",9]
["ENSG00000213759","UGT2B11",4,70065669,70080449,-1,"protein_coding",10720,"UGT2B11",{"v":3.14709815271135E-13,"d":"3.15E-13"},0.706560698,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":5.4E-16,"d":"5.40E-16"},"rs2603187:rs9884390;rs2123886:rs1349849:rs386675580:rs2123886:rs9884390:rs35307342:rs4860987",9]
["ENSG00000135220","UGT2A3",4,69794181,69817509,-1,"protein_coding",79799,"UGT2A3",{"v":5.00169122908013e-06,"d":"5.00E-06"},0.402338316,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.7e-15,"d":"7.70E-15"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342",9]
["ENSG00000135226","UGT2B28",4,70146217,70160768,1,"protein_coding",54490,"UGT2B28",{"v":6.44395718165304e-08,"d":"6.44E-08"},-0.023007521,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.7e-15,"d":"7.70E-15"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342",9]
["ENSG00000173610","UGT2A1",4,70454135,70518965,-1,"protein_coding",10941,"UGT2A1",{"v":2.73195454586815E-11,"d":"2.73E-11"},-0.281771314,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":7.7e-15,"d":"7.70E-15"},"rs35307342:rs9884390:rs386675580:rs2603187:rs1349849:rs9884390;rs2123886:rs2123886",9]
["ENSG00000271271","UGT2A2",4,70454135,70505360,-1,"protein_coding",574537,"UGT2A2",{"v":2.32634948326899e-07,"d":"2.33E-07"},-0.31710536,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":7.7e-15,"d":"7.70E-15"},"rs35307342:rs9884390:rs386675580:rs2603187:rs1349849:rs9884390;rs2123886:rs2123886",9]
["ENSG00000270386","UGT2A1",4,70454912,70518967,-1,"protein_coding",10941,"UGT2A1","NA",-0.281771314,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":7.7e-15,"d":"7.70E-15"},"rs35307342:rs9884390:rs386675580:rs2603187:rs1349849:rs9884390;rs2123886:rs2123886",9]
["ENSG00000083896","YTHDC1",4,69176105,69215807,-1,"protein_coding",91746,"YTHDC1",0.999999898691266,-1.324074711,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.2e-13,"d":"1.20E-13"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342",9]
["ENSG00000087128","TMPRSS11E",4,69313167,69363322,1,"protein_coding",28983,"TMPRSS11E",{"v":3.75424420546756E-5,"d":"3.75E-05"},0.26253994,112,22.5,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2e-13,"d":"1.20E-13"},"rs386675580;rs2603187;rs1349849;rs9884390;rs2123886;rs35307342;rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342",9]
["ENSG00000156096","UGT2B4",4,70345883,70391732,-1,"protein_coding",7363,"UGT2B4",{"v":8.44718840140518e-11,"d":"8.45E-11"},0.451804371,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.2e-13,"d":"1.20E-13"},"rs2603187:rs386675580:rs9884390;rs2123886:rs2123886:rs9884390:rs1349849:rs35307342",9]
["ENSG00000196620","UGT2B15",4,69512348,69536346,-1,"protein_coding",7366,"UGT2B15",{"v":1.92098648554063e-10,"d":"1.92E-10"},0.677329965,0,0,0,"NA","NA","NA","NA","Yes","Liver","NA","rs9884390:rs4860987",9]
["ENSG00000164398","ACSL6",5,131142683,131347936,-1,"protein_coding",23305,"ACSL6",0.088562272207543,-1.292579097,0,0,16,1.07859E-4,0.000573997,"GTEx/v8/Pancreas","+","Yes","IMR90:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380",10]
["ENSG00000164400","CSF2",5,131409483,131411859,1,"protein_coding",1437,"CSF2",0.803849286352491,-0.384982343,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs272863;rs200800380:rs200800380:rs272863",10]
["ENSG00000072682","P4HA2",5,131527531,131631008,-1,"protein_coding",8974,"P4HA2",{"v":6.46128411074688e-05,"d":"6.46E-05"},-0.308598295,27,18.28,151,{"v":3.21815e-27,"d":"3.22E-27"},{"v":2.11549e-31,"d":"2.12E-31"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380;5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs200800380:rs200800380:rs272863",10]
["ENSG00000131435","PDLIM4",5,131593364,131609147,1,"protein_coding",8572,"PDLIM4",0.924088701530717,-0.066167667,17,18.28,151,{"v":4.24856e-20,"d":"4.25E-20"},{"v":6.02052e-16,"d":"6.02E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000197208","SLC22A4",5,131630136,131679899,1,"protein_coding",6583,"SLC22A4",{"v":4.64079476855844e-06,"d":"4.64E-06"},-0.51561879,83,13.88,151,{"v":2.7801e-09,"d":"2.78E-09"},{"v":6.7175e-07,"d":"6.72E-07"},"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000197375","SLC22A5",5,131705444,131731306,1,"protein_coding",6584,"SLC22A5",{"v":4.90000271154311e-09,"d":"4.90E-09"},0.858089401,56,21.7,151,{"v":1.27641E-27,"d":"1.28E-27"},{"v":6.23252e-22,"d":"6.23E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380;rs200800380:5:131664516_TTATATA_T:rs200800380",10]
["ENSG00000197536","C5orf56",5,131746328,131811736,1,"protein_coding",441108,"C5orf56",0.107649237505837,"NA",0,0,74,{"v":1.58901E-6,"d":"1.59E-06"},{"v":3.3657e-48,"d":"3.37E-48"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000125347","IRF1",5,131817301,131826490,-1,"protein_coding",3659,"IRF1",0.867788618113854,0.555445443,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Psoas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs272863;rs200800380:rs272863:rs200800380",10]
["ENSG00000113525","IL5",5,131877136,131892530,-1,"protein_coding",3567,"IL5",0.0283744149089649,-0.161789195,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000113522","RAD50",5,131891711,131980313,1,"protein_coding",10111,"RAD50",{"v":3.45027967852237e-15,"d":"3.45E-15"},-1.018272128,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000169194","IL13",5,131991955,131996802,1,"protein_coding",3596,"IL13",0.0257146912157871,0.123554035,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000113520","IL4",5,132009678,132018368,1,"protein_coding",3565,"IL4",0.168021415276942,-0.004195228,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000131437","KIF3A",5,132028320,132073330,-1,"protein_coding",11127,"KIF3A",0.992416127781631,-0.460356314,0,0,5,{"v":7.98784e-05,"d":"7.99E-05"},{"v":1.44548e-23,"d":"1.45E-23"},"GTEx/v8/Artery_Tibial","+","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000205089","CCNI2",5,132083137,132089856,1,"protein_coding",645121,"CCNI2",{"v":4.53255419093452e-05,"d":"4.53E-05"},0.828805181,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000164402","2008-09-01",5,132086509,132142933,-1,"protein_coding",23176,"2008-09-01",0.954285718069544,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000198944","SOWAHA",5,132149033,132152488,1,"protein_coding",134548,"SOWAHA","NA",0.065648167,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000164403","SHROOM1",5,132157833,132166590,-1,"protein_coding",134549,"SHROOM1",0.00959554880204162,-0.760290944,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs272863;rs200800380:rs200800380:rs272863",10]
["ENSG00000164404","GDF9",5,132196873,132202576,-1,"protein_coding",2661,"GDF9",{"v":1.19472233006091e-05,"d":"1.19E-05"},0.352487907,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000164405","UQCRQ",5,132202252,132203723,1,"protein_coding",27089,"UQCRQ",0.0919129783108912,-0.564493203,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000164406","LEAP2",5,132208014,132210738,1,"protein_coding",116842,"LEAP2",0.00789837798993102,1.43844583,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs272863:rs200800380",10]
["ENSG00000072364","AFF4",5,132211071,132299326,-1,"protein_coding",27125,"AFF4",0.999997450786603,-1.861324311,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000213585","VDAC1",5,133307606,133340824,-1,"protein_coding",7416,"VDAC1",0.975595138410154,-0.326089734,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380",10]
["ENSG00000113558","SKP1",5,133484633,133512729,-1,"protein_coding",6500,"SKP1",0.224830619473668,2.132007545,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T:rs200800380:rs272863",10]
["ENSG00000155329","ZCCHC10",5,132332677,132362296,-1,"protein_coding",54819,"ZCCHC10",0.16080191147859,-0.209780051,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878",{"v":6.7e-09,"d":"6.70E-09"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T",10]
["ENSG00000170606","HSPA4",5,132387654,132442141,1,"protein_coding",3308,"HSPA4",0.999958225713848,-0.069630552,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878",{"v":6.7e-09,"d":"6.70E-09"},"5:131664516_TTATATA_T;rs272863;rs200800380:5:131664516_TTATATA_T",10]
["ENSG00000158987","RAPGEF6",5,130759614,130970929,-1,"protein_coding",51735,"RAPGEF6",0.998026273148455,-0.743538794,0,0,10,0.000110428,{"v":5.68575e-08,"d":"5.69E-08"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"5:131664516_TTATATA_T;rs272863",10]
["ENSG00000161904","LEMD2",6,33738979,33756913,-1,"protein_coding",221496,"LEMD2",0.302373361272148,0.392920076,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961:rs114863007",11]
["ENSG00000272325","NUDT3",6,34247456,34360451,-1,"protein_coding",11165,"NUDT3",0.876816622471426,0.134938478,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961:rs114863007",11]
["ENSG00000196821","C6orf106",6,34555065,34664636,-1,"protein_coding",64771,"C6orf106",0.454029671085684,-1.135549043,42,14.17,97,{"v":1.00433e-18,"d":"1.00E-18"},{"v":2.73886e-27,"d":"2.74E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs114863007;rs59136961;rs59136961:rs114863007:rs59136961",11]
["ENSG00000124562","SNRPC",6,34725183,34741571,1,"protein_coding",6631,"SNRPC",0.727261777653869,-0.351120295,17,15.81,97,{"v":4.04616e-11,"d":"4.05E-11"},{"v":1.95691e-18,"d":"1.96E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961;rs114863007;rs59136961:rs114863007",11]
["ENSG00000065060","UHRF1BP1",6,34759857,34850915,1,"protein_coding",54887,"UHRF1BP1",{"v":2.46541297366596e-07,"d":"2.47E-07"},-0.83035352,43,15.05,97,{"v":4.65612E-22,"d":"4.66E-22"},{"v":1.98454e-106,"d":"1.98E-106"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961;rs114863007;rs59136961:rs114863007:rs114863007",11]
["ENSG00000064995","TAF11",6,34845555,34855866,-1,"protein_coding",6882,"TAF11",0.875431936618392,-0.232568972,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961:rs114863007",11]
["ENSG00000064999","ANKS1A",6,34857042,35059179,1,"protein_coding",23294,"ANKS1A",0.84685967793139,0.260682535,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961:rs114863007",11]
["ENSG00000124678","TCP11",6,35085848,35116387,-1,"protein_coding",6954,"TCP11",{"v":4.00945484653237e-05,"d":"4.01E-05"},-0.41353592,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961:rs114863007:rs114863007;rs59136961",11]
["ENSG00000146197","SCUBE3",6,35182190,35220856,1,"protein_coding",222663,"SCUBE3",0.9999837065276,-0.692415276,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs59136961:rs114863007",11]
["ENSG00000112514","CUTA",6,33384219,33386094,-1,"protein_coding",51596,"CUTA",{"v":1.14218167340545E-5,"d":"1.14E-05"},-0.619995669,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs114863007",11]
["ENSG00000197283","SYNGAP1",6,33387847,33421466,1,"protein_coding",8831,"SYNGAP1",0.999998449747972,-1.109120657,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs114863007",11]
["ENSG00000204188","GGNBP1",6,33551515,33556803,1,"protein_coding",449520,"GGNBP1","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs114863007:rs59136961",11]
["ENSG00000137288","UQCC2",6,33662070,33679504,-1,"protein_coding",84300,"UQCC2",0.0595477327271092,0.254207876,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs114863007",11]
["ENSG00000161896","IP6K3",6,33689444,33714762,-1,"protein_coding",117283,"IP6K3",0.0485338526527661,1.72324211,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs59136961:rs114863007",11]
["ENSG00000096395","MLN",6,33762450,33771788,-1,"protein_coding",4295,"MLN",0.00165857384360036,0.983257947,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs59136961:rs114863007",11]
["ENSG00000124493","GRM4",6,33989628,34123399,-1,"protein_coding",2914,"GRM4",0.979350085369263,-0.635218754,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-8,"d":"1.40E-08"},"rs59136961:rs114863007",11]
["ENSG00000186577","C6orf1",6,34214157,34217247,-1,"protein_coding",221491,"C6orf1",0.29871864309512,-0.83430399,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs59136961:rs114863007",11]
["ENSG00000270800","RPS10-NUDT3",6,34256547,34393825,-1,"protein_coding",100529239,"RPS10-NUDT3","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs59136961:rs114863007",11]
["ENSG00000124614","RPS10",6,34385231,34393902,-1,"protein_coding",6204,"RPS10",0.946462997504496,0.20471765,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs59136961:rs114863007",11]
["ENSG00000124507","PACSIN1",6,34433916,34503006,1,"protein_coding",29993,"PACSIN1",0.991339222233708,-1.593899928,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs59136961:rs114863007",11]
["ENSG00000124664","SPDEF",6,34505579,34524110,-1,"protein_coding",25803,"SPDEF",0.711825442176907,-0.407039982,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs59136961:rs114863007",11]
["ENSG00000065029","ZNF76",6,35226686,35263762,1,"protein_coding",7629,"ZNF76",{"v":5.07288621916122e-16,"d":"5.07E-16"},0.397539219,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs59136961:rs114863007:rs114863007;rs59136961",11]
["ENSG00000096060","FKBP5",6,35541362,35696360,-1,"protein_coding",2289,"FKBP5",0.498849476622916,-0.767039177,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs114863007",11]
["ENSG00000112079","STK38",6,36461669,36515247,-1,"protein_coding",11329,"STK38",0.853295086026932,-0.412586124,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs114863007;rs59136961:rs114863007",11]
["ENSG00000137392","CLPS",6,35762759,35765088,-1,"protein_coding",1208,"CLPS",0.0562747598072514,0.768244845,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.7E-7,"d":"3.70E-07"},"rs59136961:rs114863007;rs59136961",11]
["ENSG00000023892","DEF6",6,35265595,35289548,1,"protein_coding",50619,"DEF6",0.976824149100722,0.153810841,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-06,"d":"1.00E-06"},"rs59136961",11]
["ENSG00000112041","TULP1",6,35465651,35480715,-1,"protein_coding",7287,"TULP1",0.80790432015979,-0.139076605,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-06,"d":"1.10E-06"},"rs59136961",11]
["ENSG00000172461","FUT9",6,96463860,96663488,1,"protein_coding",10690,"FUT9",0.0813711620521245,5.37195294,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3e-06,"d":"3.00E-06"},"rs6931604",12]
["ENSG00000184486","POU3F2",6,99282580,99286660,1,"protein_coding",5454,"POU3F2","NA",-0.738809759,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":3e-06,"d":"3.00E-06"},"rs6931604",12]
["ENSG00000196313","POM121",7,72349936,72421979,1,"protein_coding",9883,"POM121","NA",-1.370618997,0,0,57,{"v":8.97114e-08,"d":"8.97E-08"},{"v":1.50688E-66,"d":"1.51E-66"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868;rs62466318;rs33951980;rs62466318:rs33951980:rs62466318",15]
["ENSG00000130305","NSUN5",7,72716514,72722864,-1,"protein_coding",55695,"NSUN5",{"v":1.45415268581091e-06,"d":"1.45E-06"},-0.276519006,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.1e-11,"d":"3.10E-11"},"rs33951980:rs138574868;rs62466318:rs138574868:rs62466318",15]
["ENSG00000009954","BAZ1B",7,72854728,72936608,-1,"protein_coding",9031,"BAZ1B",0.999999562861573,-1.106984422,35,8.812,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-11,"d":"3.10E-11"},"rs33951980;rs138574868;rs62466318;rs138574868:rs33951980:rs138574868;rs62466318:rs62466318",15]
["ENSG00000106635","BCL7B",7,72950686,72972332,-1,"protein_coding",9275,"BCL7B",0.706637383924404,-0.386261382,15,14.54,67,{"v":2.54871e-06,"d":"2.55E-06"},{"v":3.40292E-13,"d":"3.40E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868;rs33951980;rs62466318;rs62466318:rs33951980",15]
["ENSG00000106638","TBL2",7,72983262,72993121,-1,"protein_coding",26608,"TBL2",0.00437650656905421,8.921304858,30,10.3,45,{"v":1.29213e-05,"d":"1.29E-05"},{"v":4.93874e-46,"d":"4.94E-46"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","No","NA",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868;rs33951980;rs62466318",15]
["ENSG00000009950","MLXIPL",7,73007524,73038873,-1,"protein_coding",51085,"MLXIPL",0.676823094036297,0.477223974,61,19.09,109,{"v":5.28937e-28,"d":"5.29E-28"},{"v":1.10979e-22,"d":"1.11E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868;rs62466318;rs33951980;rs33951980:rs138574868",15]
["ENSG00000176428","VPS37D",7,73082155,73086442,1,"protein_coding",155382,"VPS37D",0.656347210550458,"NA",0,0,35,{"v":3.82464E-7,"d":"3.82E-07"},{"v":1.34286e-08,"d":"1.34E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868;rs62466318;rs33951980;rs138574868:rs33951980:rs138574868;rs62466318:rs138574868;rs33951980:rs62466318",15]
["ENSG00000106089","STX1A",7,73113536,73134002,-1,"protein_coding",6804,"STX1A",0.910475757164848,-0.07051921,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868;rs62466318:rs33951980",15]
["ENSG00000165171","WBSCR27",7,73248920,73256865,-1,"protein_coding",155368,"WBSCR27",0.0679116625114122,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.1e-11,"d":"3.10E-11"},"rs138574868:rs33951980:rs138574868;rs62466318",15]
["ENSG00000106683","LIMK1",7,73497263,73536855,1,"protein_coding",3984,"LIMK1",0.990896287164463,-0.781218183,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.1e-11,"d":"3.10E-11"},"rs33951980:rs138574868;rs62466318",15]
["ENSG00000106665","CLIP2",7,73703805,73820273,1,"protein_coding",7461,"CLIP2",0.999881647285659,0.2522342,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.1e-11,"d":"3.10E-11"},"rs33951980:rs138574868;rs62466318",15]
["ENSG00000106077","ABHD11",7,73150424,73153197,-1,"protein_coding",83451,"ABHD11",{"v":9.03291221619057e-06,"d":"9.03E-06"},0.148517676,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4e-11,"d":"4.00E-11"},"rs33951980:rs138574868;rs62466318:rs138574868;rs62466318;rs33951980:rs62466318;rs33951980",15]
["ENSG00000165215","CLDN3",7,73183328,73184600,-1,"protein_coding",1365,"CLDN3",0.678537320145956,-0.798792708,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":4e-11,"d":"4.00E-11"},"rs138574868;rs62466318",15]
["ENSG00000106682","EIF4H",7,73588575,73611431,1,"protein_coding",7458,"EIF4H",0.922544880243499,-1.500430355,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":5.2e-11,"d":"5.20E-11"},"rs33951980:rs138574868;rs62466318",15]
["ENSG00000146755","TRIM50",7,72726535,72742085,-1,"protein_coding",135892,"TRIM50",{"v":2.72561665019464E-6,"d":"2.73E-06"},-0.790238603,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8E-10,"d":"1.80E-10"},"rs33951980:rs138574868;rs62466318:rs138574868:rs62466318",15]
["ENSG00000077800","FKBP6",7,72742167,72772634,1,"protein_coding",8468,"FKBP6",0.13060063873413,-0.33452228,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8E-10,"d":"1.80E-10"},"rs33951980:rs138574868;rs62466318:rs138574868:rs62466318",15]
["ENSG00000188763","FZD9",7,72848109,72850450,1,"protein_coding",8326,"FZD9","NA","NA",4,3.057,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-10,"d":"1.80E-10"},"rs33951980;rs138574868;rs62466318;rs33951980:rs138574868;rs62466318:rs138574868:rs62466318",15]
["ENSG00000049541","RFC2",7,73645829,73668774,-1,"protein_coding",5982,"RFC2",{"v":4.04212746398499e-05,"d":"4.04E-05"},-0.396975582,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8E-10,"d":"1.80E-10"},"rs33951980:rs138574868;rs62466318",15]
["ENSG00000175877","WBSCR28",7,73275489,73280223,1,"protein_coding",135886,"WBSCR28",{"v":1.58800503099146E-6,"d":"1.59E-06"},0.424364093,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.2e-10,"d":"2.20E-10"},"rs138574868;rs62466318:rs33951980",15]
["ENSG00000086730","LAT2",7,73613982,73644161,1,"protein_coding",7462,"LAT2",0.000691063098880473,-0.479096813,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-10,"d":"2.30E-10"},"rs33951980:rs62466318",15]
["ENSG00000105953","OGDH",7,44646171,44748665,1,"protein_coding",4967,"OGDH",0.993695121200126,-0.070196077,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-09,"d":"1.60E-09"},"rs73109460",14]
["ENSG00000122515","ZMIZ2",7,44788180,44809477,1,"protein_coding",83637,"ZMIZ2",0.999620382312933,0.41682603,17,8.079,19,{"v":3.30135e-13,"d":"3.30E-13"},{"v":8.21167E-9,"d":"8.21E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","+","No","NA",{"v":1.6e-09,"d":"1.60E-09"},"rs73109460",14]
["ENSG00000196262","PPIA",7,44836279,44864163,1,"protein_coding",5478,"PPIA",0.808049495342876,0.430904546,0,0,12,{"v":1.56786e-05,"d":"1.57E-05"},{"v":2.29167E-5,"d":"2.29E-05"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.6e-09,"d":"1.60E-09"},"rs73109460",14]
["ENSG00000146676","PURB",7,44915896,44924960,-1,"protein_coding",5814,"PURB",0.605935032790202,-2.57194086,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-09,"d":"1.60E-09"},"rs73109460",14]
["ENSG00000136270","TBRG4",7,45139699,45151646,-1,"protein_coding",9238,"TBRG4",0.780939582899283,-0.259398376,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.6e-09,"d":"1.60E-09"},"rs73109460",14]
["ENSG00000155428","TRIM74",7,72430016,72439997,-1,"protein_coding",378108,"TRIM74",0.780333820359187,-0.947438302,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-09,"d":"8.80E-09"},"rs33951980:rs138574868;rs62466318",15]
["ENSG00000240230","COX19",7,938415,1015235,-1,"protein_coding",90639,"COX19",0.000108651204575146,1.398679492,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000073067","CYP2W1",7,1022835,1029276,1,"protein_coding",54905,"CYP2W1",9.809162819603371E-4,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000146540","C7orf50",7,1036622,1177896,-1,"protein_coding",84310,"C7orf50",1.39620778717545E-3,1.072402049,0,0,18,{"v":1.22195E-6,"d":"1.22E-06"},0.000318302,"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000164849","GPR146",7,1084212,1098897,1,"protein_coding",115330,"GPR146",0.00279412642316597,0.355400189,0,0,12,{"v":5.26182e-06,"d":"5.26E-06"},0.00544126,"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000164850","GPER1",7,1121844,1133451,1,"protein_coding",2852,"GPER1",0.725420978638944,0.809124212,0,0,19,{"v":3.10333E-14,"d":"3.10E-14"},{"v":2.1766e-19,"d":"2.18E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta","+","Yes","Promoter_anchored_loops:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000178381","ZFAND2A",7,1191707,1200395,-1,"protein_coding",90637,"ZFAND2A",0.000389857167343114,"NA",6,4.984,19,{"v":2.92911e-29,"d":"2.93E-29"},{"v":2.41505e-56,"d":"2.42E-56"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000164853","UNCX",7,1272543,1276954,1,"protein_coding",340260,"UNCX","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.4E-8,"d":"3.40E-08"},"rs35177659",13]
["ENSG00000136271","DDX56",7,44605016,44614650,-1,"protein_coding",54606,"DDX56",{"v":3.51574131414912e-06,"d":"3.52E-06"},-0.604939687,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.8E-8,"d":"6.80E-08"},"rs73109460",14]
["ENSG00000158604","TMED4",7,44617493,44621886,-1,"protein_coding",222068,"TMED4",0.292927703052725,0.480384772,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.8E-8,"d":"6.80E-08"},"rs73109460",14]
["ENSG00000164877","MICALL2",7,1468101,1499138,-1,"protein_coding",79778,"MICALL2",{"v":7.76189169980639e-17,"d":"7.76E-17"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.3e-07,"d":"4.30E-07"},"rs35177659",13]
["ENSG00000164880","INTS1",7,1509913,1545489,-1,"protein_coding",26173,"INTS1",0.22412137484881,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.3e-07,"d":"4.30E-07"},"rs35177659",13]
["ENSG00000147687","TATDN1",8,125500726,125551699,-1,"protein_coding",83940,"TATDN1",{"v":1.72640600686597e-08,"d":"1.73E-08"},0.357863168,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-32,"d":"2.30E-32"},"rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309",18]
["ENSG00000147684","NDUFB9",8,125551344,125580751,1,"protein_coding",4715,"NDUFB9",0.0428894468164687,-0.016587227,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-32,"d":"2.30E-32"},"rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309",18]
["ENSG00000180938","ZNF572",8,125985540,125991631,1,"protein_coding",137209,"ZNF572",0.000651450621070101,-0.137914163,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":2.3e-32,"d":"2.30E-32"},"rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G",18]
["ENSG00000104549","SQLE",8,126010739,126034525,1,"protein_coding",6713,"SQLE",0.91297067975512,1.171693492,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-32,"d":"2.30E-32"},"rs4360309:rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G",18]
["ENSG00000164961","KIAA0196",8,126036502,126104082,-1,"protein_coding",9897,"KIAA0196",{"v":4.81024990398197e-13,"d":"4.81E-13"},-0.762157486,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-32,"d":"2.30E-32"},"rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309",18]
["ENSG00000156831","NSMCE2",8,126103921,126379362,1,"protein_coding",286053,"NSMCE2",0.0724507212755206,-0.471934498,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-32,"d":"2.30E-32"},"rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309",18]
["ENSG00000136997","MYC",8,128747680,128753674,1,"protein_coding",4609,"MYC","NA",-0.253124713,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.3e-32,"d":"2.30E-32"},"rs112875651;rs2954021:rs33924196:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G",18]
["ENSG00000147324","MFHAS1",8,8640864,8751155,-1,"protein_coding",9258,"MFHAS1",{"v":2.22820045783843E-5,"d":"2.23E-05"},0.9551839,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesendoderm:Trophoblast-like_Cell",{"v":4.9e-17,"d":"4.90E-17"},"rs9987289;rs7357361:rs10102352:rs7357361:rs7012637:rs9987289:rs34290760:rs9987289;rs7357361;rs7008413",16]
["ENSG00000104626","ERI1",8,8859657,8974256,1,"protein_coding",90459,"ERI1",0.000454685197816091,0.949360106,0,0,25,{"v":1.7192E-6,"d":"1.72E-06"},{"v":1.58151e-06,"d":"1.58E-06"},"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-17,"d":"4.90E-17"},"rs9987289;rs7357361;rs7008413;rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7008413:rs10102352:rs7357361:rs7357361;rs7008413:rs7008413:rs7012637",16]
["ENSG00000173281","PPP1R3B",8,8993765,9009084,-1,"protein_coding",79660,"PPP1R3B",0.0229191412335762,3.70852971,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":4.9e-17,"d":"4.90E-17"},"rs7012637:rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7357361;rs7008413",16]
["ENSG00000253426","RP11-10A14.4",8,9009252,9025646,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":4.9e-17,"d":"4.90E-17"},"rs7012637:rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7357361;rs7008413",16]
["ENSG00000173273","TNKS",8,9413424,9639856,1,"protein_coding",8658,"TNKS",0.777115954184058,1.637267498,0,0,15,{"v":7.43105e-08,"d":"7.43E-08"},0.00127623,"GTEx/v8/Liver","+","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.9e-17,"d":"4.90E-17"},"rs7012637;rs9987289;rs7357361;rs7012637:rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7008413:rs7357361:rs10102352:rs7357361;rs7008413:rs7008413",16]
["ENSG00000171044","XKR6",8,10753555,11058875,-1,"protein_coding",286046,"XKR6",0.956776701241562,0.199430911,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.9e-17,"d":"4.90E-17"},"rs7012637:rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7357361;rs7008413",16]
["ENSG00000189376","C8orf76",8,124232196,124253638,-1,"protein_coding",84933,"C8orf76",{"v":1.71944218858493e-05,"d":"1.72E-05"},-0.020072916,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.6e-13,"d":"4.60E-13"},"rs4360309",18]
["ENSG00000259305","ZHX1-C8ORF76",8,124238431,124279627,-1,"protein_coding",100533106,"ZHX1-C8ORF76",0.00105203127523669,-0.36802306,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.6e-13,"d":"4.60E-13"},"rs4360309",18]
["ENSG00000170881","RNF139",8,125486979,125500155,1,"protein_coding",11236,"RNF139",0.0608738334958745,-0.469220523,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.6e-13,"d":"4.60E-13"},"rs4360309",18]
["ENSG00000173334","TRIB1",8,126442563,126450647,1,"protein_coding",10221,"TRIB1",0.606587656595858,-0.456914247,11,6.894,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.6e-13,"d":"4.60E-13"},"rs4871598;rs12674939;rs4360309",18]
["ENSG00000175445","LPL",8,19759228,19824769,1,"protein_coding",4023,"LPL",{"v":3.33727737763241e-06,"d":"3.34E-06"},1.047176611,23,50,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5e-09,"d":"5.00E-09"},"rs117026536",17]
["ENSG00000104611","SH2D4A",8,19171128,19253729,1,"protein_coding",63898,"SH2D4A",{"v":1.53114480649588e-18,"d":"1.53E-18"},-0.083318155,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":9.9e-09,"d":"9.90E-09"},"rs117026536",17]
["ENSG00000147408","CSGALNACT1",8,19261672,19615540,-1,"protein_coding",55790,"CSGALNACT1",{"v":6.87751081149391e-05,"d":"6.88E-05"},0.406270981,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":9.9e-09,"d":"9.90E-09"},"rs117026536",17]
["ENSG00000104613","INTS10",8,19674651,19709594,1,"protein_coding",55174,"INTS10",0.984216594645776,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":9.9e-09,"d":"9.90E-09"},"rs117026536",17]
["ENSG00000036565","SLC18A1",8,20002366,20040717,-1,"protein_coding",6570,"SLC18A1",{"v":1.8888318573672e-14,"d":"1.89E-14"},0.247527783,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Mesenchymal_Stem_Cell",{"v":9.9e-09,"d":"9.90E-09"},"rs117026536",17]
["ENSG00000147416","ATP6V1B2",8,20054878,20084330,1,"protein_coding",526,"ATP6V1B2",0.991448562707497,-0.741850309,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":9.9e-09,"d":"9.90E-09"},"rs117026536",17]
["ENSG00000156011","PSD3",8,18384811,18942240,-1,"protein_coding",23362,"PSD3",0.851705649436322,1.354305318,0,0,0,"NA","NA","NA","NA","Yes","Aorta",{"v":2.3e-08,"d":"2.30E-08"},"rs117026536",17]
["ENSG00000156006","NAT2",8,18248755,18258728,1,"protein_coding",10,"NAT2",0.0226078662097717,0.267314509,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.7E-7,"d":"4.70E-07"},"rs117026536",17]
["ENSG00000165029","ABCA1",9,107543283,107690518,-1,"protein_coding",19,"ABCA1",0.00165880319635912,0.082774215,6,15.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.3e-08,"d":"3.30E-08"},"rs1800978",19]
["ENSG00000070214","SLC44A1",9,108006903,108201452,1,"protein_coding",23446,"SLC44A1",0.999253571367297,-0.569151,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs1800978",19]
["ENSG00000106701","FSD1L",9,108210077,108314714,1,"protein_coding",83856,"FSD1L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs1800978",19]
["ENSG00000186051","TAL2",9,108424738,108425367,1,"protein_coding",6887,"TAL2",0.488535069507167,0.093363904,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":3.3e-08,"d":"3.30E-08"},"rs1800978",19]
["ENSG00000171988","JMJD1C",10,64926981,65225722,-1,"protein_coding",221037,"JMJD1C",0.999999999962643,-0.552974329,181,20.3,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.1e-19,"d":"4.10E-19"},"rs149727843;rs141929745;rs7924036;rs34124994;rs557044785;10:64982989_GT_G;rs764351876;rs201220977;10:65036225_CA_C;rs141929745:rs7924036;rs557044785:rs7924036:rs7924036;rs34124994:rs7924036;rs557044785:rs141929745:rs34030237;rs746973976:rs746973976:10:65036225_CA_C:rs7924036;rs201220977:rs201220977:rs149727843:10:65262396_CA_C:rs34030237:10:64982989_GT_G:rs764351876:rs34124994:rs557044785",21]
["ENSG00000165476","REEP3",10,65281123,65384883,1,"protein_coding",221035,"REEP3",0.0129812993547476,1.398422055,132,15.42,307,{"v":1.20408E-15,"d":"1.20E-15"},{"v":1.80417e-13,"d":"1.80E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-19,"d":"4.10E-19"},"rs7924036;rs34124994;rs557044785;rs149727843;rs141929745;rs34030237;rs746973976;rs201220977;rs34124994:rs7924036:rs7924036;rs557044785:rs149727843;rs141929745:rs7924036;rs557044785:rs34124994:rs141929745:10:65262396_CA_C:10:64982989_GT_G:rs7924036;rs201220977:rs34030237:rs34030237;rs746973976:rs746973976:rs764351876:10:65036225_CA_C:rs149727843",21]
["ENSG00000182010","RTKN2",10,63942794,64028466,-1,"protein_coding",219790,"RTKN2",{"v":1.30976541627025E-14,"d":"1.31E-14"},2.546277933,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":8.5E-19,"d":"8.50E-19"},"rs149727843;rs141929745:rs7924036;rs34124994;rs557044785:rs141929745:rs7924036:10:65262396_CA_C:rs7924036;rs34124994:10:64982989_GT_G:rs7924036;rs557044785:rs34030237:rs34030237;rs746973976:rs746973976",21]
["ENSG00000150347","ARID5B",10,63661059,63856703,1,"protein_coding",84159,"ARID5B",0.999889943413299,-1.139359989,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.7e-18,"d":"4.70E-18"},"rs149727843;rs141929745:rs7924036;rs34124994;rs557044785:rs34030237;rs746973976:rs141929745:rs7924036:rs7924036;rs34124994:rs746973976:10:65262396_CA_C:rs7924036",21]
["ENSG00000170312","CDK1",10,62538089,62554610,1,"protein_coding",983,"CDK1",0.970572339309587,-0.363031251,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.5E-17,"d":"1.50E-17"},"rs141929745:rs7924036;rs34124994;rs557044785:rs149727843;rs141929745:rs7924036:10:65262396_CA_C:rs7924036;rs34124994:rs7924036;rs557044785:rs34030237:rs34030237;rs746973976:rs746973976",21]
["ENSG00000072422","RHOBTB1",10,62629196,62761198,-1,"protein_coding",9886,"RHOBTB1",0.00183822701018375,-0.452042487,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5E-17,"d":"1.50E-17"},"rs149727843;rs141929745:rs7924036:rs7924036;rs34124994;rs557044785:rs7924036;rs34124994:rs141929745:10:65262396_CA_C",21]
["ENSG00000183346","C10orf107",10,63422719,63526524,1,"protein_coding",219621,"C10orf107",0.000790930288586529,-0.769889568,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.5E-17,"d":"1.50E-17"},"rs149727843;rs141929745:rs7924036;rs34124994;rs557044785:rs141929745:rs7924036:10:65262396_CA_C:rs7924036",21]
["ENSG00000138311","ZNF365",10,64133951,64431771,1,"protein_coding",22891,"ZNF365",{"v":3.62115394483978e-05,"d":"3.62E-05"},-0.151965448,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.5E-17,"d":"1.50E-17"},"rs149727843;rs141929745:rs7924036:rs7924036;rs34124994;rs557044785:rs7924036;rs34124994:rs141929745:10:65262396_CA_C:rs7924036;rs557044785:rs34030237:rs34030237;rs746973976:rs746973976",21]
["ENSG00000181915","ADO",10,64564516,64568238,1,"protein_coding",84890,"ADO",0.745072785344825,-0.496919278,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90",{"v":1.5E-17,"d":"1.50E-17"},"rs149727843;rs141929745:rs7924036;rs34124994;rs557044785:rs141929745:rs7924036:10:65262396_CA_C:rs7924036",21]
["ENSG00000122877","EGR2",10,64571756,64679660,-1,"protein_coding",1959,"EGR2",0.619543204134511,-0.491267292,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-17,"d":"1.50E-17"},"rs141929745:rs7924036;rs34124994;rs557044785:rs149727843;rs141929745:rs7924036:10:65262396_CA_C:rs7924036;rs34124994:rs746973976",21]
["ENSG00000148572","NRBF2",10,64893050,64914783,1,"protein_coding",29982,"NRBF2",0.0821062414135336,-0.409712515,21,13.93,12,{"v":1.94734e-05,"d":"1.95E-05"},0.0157243,"GTEx/v8/Artery_Tibial","+","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-17,"d":"1.50E-17"},"rs149727843;rs141929745;rs7924036;rs34124994;rs557044785;rs34030237;rs141929745:rs7924036;rs557044785:rs149727843;rs141929745:rs7924036:10:65262396_CA_C:rs7924036;rs34124994:rs7924036;rs557044785:rs34030237:rs34030237;rs746973976:rs746973976",21]
["ENSG00000138109","CYP2C9",10,96698415,96749147,1,"protein_coding",1559,"CYP2C9",{"v":2.53599347417585E-8,"d":"2.54E-08"},0.077353466,38,8.103,18,{"v":1.67662e-05,"d":"1.68E-05"},{"v":1.43644e-09,"d":"1.44E-09"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Liver",{"v":9.5e-11,"d":"9.50E-11"},"rs55891451;rs11596236;rs11596236:rs55891451",22]
["ENSG00000138115","CYP2C8",10,96796530,96829254,-1,"protein_coding",1558,"CYP2C8",{"v":5.35039546572966e-12,"d":"5.35E-12"},0.073211053,0,0,21,1.12151E-4,{"v":1.88917e-11,"d":"1.89E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","+","No","NA",{"v":9.5e-11,"d":"9.50E-11"},"rs55891451",22]
["ENSG00000173124","C10orf129",10,96953957,96988685,1,"protein_coding",142827,"C10orf129",0.0112101925841759,-0.050977718,0,0,47,{"v":3.91712E-20,"d":"3.92E-20"},{"v":5.72937e-59,"d":"5.73E-59"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary","+","No","NA",{"v":9.5e-11,"d":"9.50E-11"},"rs55891451;rs11596236",22]
["ENSG00000107438","PDLIM1",10,96997329,97050781,-1,"protein_coding",9124,"PDLIM1",{"v":1.38008290255861E-5,"d":"1.38E-05"},"NA",0,0,31,{"v":3.74346e-05,"d":"3.74E-05"},1.75862E-3,"GTEx/v8/Adipose_Subcutaneous","+","Yes","hESC",{"v":9.5e-11,"d":"9.50E-11"},"rs55891451;rs11596236:rs55891451",22]
["ENSG00000269948","RP11-248J23.6",10,97709725,97744785,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":9.5e-11,"d":"9.50E-11"},"rs55891451:rs11596236",22]
["ENSG00000108242","CYP2C18",10,96443251,96495947,1,"protein_coding",1562,"CYP2C18",{"v":5.267291853526e-08,"d":"5.27E-08"},0.613728973,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":1.3e-10,"d":"1.30E-10"},"rs55891451:rs11596236",22]
["ENSG00000165841","CYP2C19",10,96447911,96613017,1,"protein_coding",1557,"CYP2C19",{"v":2.53768601148421e-10,"d":"2.54E-10"},-0.174574379,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":1.3e-10,"d":"1.30E-10"},"rs55891451:rs11596236",22]
["ENSG00000173088","C10orf131",10,97667360,97698480,1,"protein_coding",387707,"C10orf131","NA",1.318571629,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":5.5e-10,"d":"5.50E-10"},"rs11596236:rs55891451",22]
["ENSG00000078114","NEBL",10,21068902,21463116,-1,"protein_coding",10529,"NEBL",{"v":5.76983793061894e-24,"d":"5.77E-24"},-0.148103405,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000204683","C10orf113",10,21414692,21435488,-1,"protein_coding",387638,"C10orf113",0.00753778234040987,-0.171514,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000204682","CASC10",10,21781587,21786191,-1,"protein_coding",399726,"CASC10",0.02005486166772,-1.904040172,0,0,114,{"v":1.31051E-7,"d":"1.31E-07"},0.000145226,"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000180592","SKIDA1",10,21802407,21814611,-1,"protein_coding",387640,"SKIDA1","NA",-1.174748692,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000078403","MLLT10",10,21823094,22032559,1,"protein_coding",8028,"MLLT10",0.999583699307582,-0.518307189,33,9.043,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000136770","DNAJC1",10,22045466,22292698,-1,"protein_coding",64215,"DNAJC1",{"v":1.42208526512983E-8,"d":"1.42E-08"},"NA",106,15.8,0,"NA","NA","NA","NA","No","NA",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000223601","EBLN1",10,22497743,22498950,-1,"protein_coding",340900,"EBLN1",{"v":6.91019370514168e-05,"d":"6.91E-05"},-0.172630201,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000148444","COMMD3",10,22604903,22609235,1,"protein_coding",23412,"COMMD3",0.00742011460272826,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000269897","COMMD3-BMI1",10,22605317,22618471,1,"protein_coding",100532731,"COMMD3-BMI1",0.0225993476495416,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000168283","BMI1",10,22610140,22620413,1,"protein_coding",648,"BMI1",0.515144747396546,-0.143840631,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000077327","SPAG6",10,22634399,22743153,1,"protein_coding",9576,"SPAG6",{"v":7.41292381390175e-06,"d":"7.41E-06"},-0.814068431,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000150867","PIP4K2A",10,22823778,23003484,-1,"protein_coding",5305,"PIP4K2A",0.788196366835575,1.15026899,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000165309","ARMC3",10,23216953,23326518,1,"protein_coding",219681,"ARMC3",{"v":4.53373054750587e-08,"d":"4.53E-08"},-0.253773206,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000148450","MSRB2",10,23384435,23410942,1,"protein_coding",22921,"MSRB2",4.24761100040581E-3,-0.322431289,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000165312","OTUD1",10,23728198,23731308,1,"protein_coding",220213,"OTUD1","NA",-0.182613088,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.6e-09,"d":"6.60E-09"},"10:22255616_CT_C",20]
["ENSG00000119969","HELLS",10,96305547,96373662,1,"protein_coding",3070,"HELLS",0.999418431126719,0.065854322,0,0,13,{"v":6.22444e-06,"d":"6.22E-06"},{"v":1.74635E-17,"d":"1.75E-17"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":2.3e-08,"d":"2.30E-08"},"rs11596236",22]
["ENSG00000269879","AL353583.1",10,24770273,24770632,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.1e-07,"d":"1.10E-07"},"10:22255616_CT_C",20]
["ENSG00000241058","NSUN6",10,18834490,18940551,-1,"protein_coding",221078,"NSUN6",{"v":1.72775122895768E-14,"d":"1.73E-14"},-0.298655594,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":5.6e-06,"d":"5.60E-06"},"10:22255616_CT_C",20]
["ENSG00000271786","RP11-139J15.7",10,18931405,18944123,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":5.6e-06,"d":"5.60E-06"},"10:22255616_CT_C",20]
["ENSG00000165997","ARL5B",10,18948334,18970568,1,"protein_coding",221079,"ARL5B",0.463976138130045,0.319437506,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":5.6e-06,"d":"5.60E-06"},"10:22255616_CT_C",20]
["ENSG00000089597","GANAB",11,62392298,62414104,-1,"protein_coding",23193,"GANAB",0.99994841038629,-1.005335984,0,0,7,{"v":4.0164e-06,"d":"4.02E-06"},0.0180353,"GTEx/v8/Liver","-","Yes","GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":7.7e-285,"d":"7.70E-285"},"rs174597;rs117198764:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000167994","RAB3IL1",11,61664773,61687741,-1,"protein_coding",5866,"RAB3IL1",0.000894540821499919,-0.364568465,83,15.59,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.2E-283,"d":"1.20E-283"},"rs36047269;11:61648649_AAATG_A;rs174453;rs528285;rs116962591;rs529349261;rs412334;rs174468;rs174472;rs174473;rs174477;rs7115739;11:61670459_AC_A;rs117828446;rs11230813;rs1076180;rs148623923;rs61898562;rs117664091;rs540613;rs35371411;rs2524287;rs2727258;rs174480;rs2736598;rs76133863;rs11230827;rs149037697;rs182407676;rs17156580;rs747321234;rs11825591;rs2524292;rs17156254:rs769908354;rs3018327:rs769908354:rs198441:rs117494202:rs198435;rs2238001;rs199969886:rs198422:rs198459:rs9326418:rs77053629:rs387137:rs61895466:rs259889:rs116262432:rs259869;rs11230885:rs11230896:rs12226389;rs71053010:rs750567872;rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs259869:rs72926147:rs71053010:rs10909647;rs61893681;rs61895504:rs199789685:rs61895504:rs61895504;rs61893661:rs72928167:rs2736595:rs74556176;rs60517521:rs195161;rs2736595:rs183176:rs112657532:rs195161:rs74754540:rs17156580:rs149698:rs56215258;rs4963440:11:61742244_CAA_C;rs56215258:rs56215258:rs111605165:rs60517521:11:61742244_CAA_C;rs56215258;rs35686945:rs71490346:11:61742244_CAA_C:rs117832375:rs4343027;rs117832375:rs76978219:rs4343027:rs56215258;rs778782193;rs35686945:11:61742244_CAA_C;rs35686945:rs73493300:rs35686945:rs778782193:rs56215258;rs33972521;rs4963440:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:11:61637710_CA_C:rs113003506:rs11407273:rs75306442:rs7115739:rs36047269:rs174453:rs7942717:11:61648649_AAATG_A:rs528285:rs116962591:rs529349261:rs174468:rs174472:rs174453;rs174477:11:61670459_AC_A:rs117828446:rs11230813:rs174473:rs1076180:rs148623923:rs174477:rs61898562:rs174453;rs174477:rs117664091:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908:rs61893681:rs10909647;rs61893681:rs1792909;rs11230920;rs386754192:rs140534658:rs10897232;rs7943493;rs386754192:rs571932724",23]
["ENSG00000167995","BEST1",11,61717293,61732987,1,"protein_coding",7439,"BEST1",{"v":4.88561552823397e-08,"d":"4.89E-08"},0.261397399,85,19.26,11,{"v":4.08457e-07,"d":"4.08E-07"},0.000730003,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.2E-283,"d":"1.20E-283"},"rs2524292;rs74556176;rs182407676;rs2736598;rs2524293;rs60517521;rs2521572;rs74754540;rs2727260;rs2009875;rs195161;rs2736595;rs174481;rs112657532;rs183176;rs17156580;rs149698;rs56215258;rs4963440;11:61742244_CAA_C;rs111605165;rs35686945;rs71490346;rs117832375;rs76978219;rs778782193;rs528285:rs116962591:rs529349261:rs412334:rs174468:11:61648649_AAATG_A:rs174472:rs174453;rs174473;rs174477:rs7115739:rs149698:rs56215258;rs4963440:11:61742244_CAA_C;rs56215258:rs56215258:rs111605165:rs60517521:rs74556176;rs60517521:11:61742244_CAA_C;rs35686945:rs71490346:rs149698;rs7935835:rs56215258;rs35686945:11:61742244_CAA_C;rs12576538;rs35686945:rs56215258;rs4963440:rs4343027:rs145379784:rs4963440:rs56215258;rs33972521;rs4963440:rs73493300:rs12576538;rs35686945:rs7935835:rs6591688:rs33972521;rs6591688:rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs11230896:rs12226389;rs71053010:rs750567872;rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs72926147:rs71053010:rs10909647;rs61893681;rs61895504:rs199789685:rs61895504:rs61895504;rs61893661:rs72928167:rs2736595:rs195161;rs2736595:rs183176:rs112657532:rs195161:rs74754540:rs17156580:11:61742244_CAA_C:rs117832375:rs4343027;rs117832375:rs76978219:11:61742244_CAA_C;rs35686945:rs35686945:rs778782193:rs7102974:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:11:61637710_CA_C:rs113003506:rs11407273:rs75306442:rs36047269:rs174453:rs7942717:11:61670459_AC_A:rs117828446:rs11230813:rs174473:rs1076180:rs148623923:rs174477:rs61898562:rs174453;rs174477:rs117664091:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908:rs61893681:rs10909647;rs61893681:rs1792909;rs11230920;rs386754192:rs140534658:rs10897232;rs7943493;rs386754192:rs571932724",23]
["ENSG00000124939","SCGB2A1",11,61976140,61981408,1,"protein_coding",4246,"SCGB2A1",0.0564012954624431,-0.285394902,41,6.046,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.2E-283,"d":"1.20E-283"},"rs386754192;rs10897232;rs12806663;rs7943493;rs536206626;rs1627693;rs117198764;rs11230985;rs7936908;rs113003506:rs174453:rs36047269:rs12806663:rs7936908:rs117198764:rs571932724:rs61893681:rs536206626;rs1627693:rs10897232;rs7943493:rs10897232:rs10909647;rs61893681:rs1792909;rs11230920;rs386754192:rs1792909:rs386754192:rs140534658:rs11230920;rs386754192:rs10897232;rs7943493:rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs11230896:rs12226389;rs71053010:rs750567872;rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs72926147:rs71053010:rs10909647;rs61893681;rs61895504:rs199789685:rs61895504:rs61895504;rs61893661:rs72928167:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:11:61637710_CA_C:rs11407273:rs75306442:rs7115739:rs7942717:11:61648649_AAATG_A:rs528285:rs116962591:rs529349261:rs174468:rs174472:rs174453;rs174473;rs174477:11:61670459_AC_A:rs117828446:rs11230813:rs174473:rs1076180:rs148623923:rs174477:rs61898562:rs174453;rs174477:rs117664091:rs540613:rs35371411:rs2524287:rs2727258:rs174480:rs2736598;rs2727258:rs76133863:rs11230827:rs149037697:rs11230827;rs182407676:rs2736598:rs17156580:rs747321234:rs11825591:rs2524292:rs182407676:rs74556176;rs182407676:rs2727274:rs2524293:rs74556176:rs74556176;rs60517521:rs2521572:rs74754540:rs2727260:rs2009875:rs195161;rs2736595:rs174481:rs2736595:rs2727260;rs112657532:rs183176:rs112657532:rs195161:rs149698:rs56215258;rs4963440:11:61742244_CAA_C;rs56215258:rs56215258:rs111605165:rs60517521:11:61742244_CAA_C;rs56215258;rs35686945:rs71490346:11:61742244_CAA_C:rs117832375:rs4343027;rs117832375:rs76978219:rs4343027:rs56215258;rs778782193;rs35686945:11:61742244_CAA_C;rs35686945:rs73493300:rs35686945:rs778782193:rs56215258;rs33972521;rs4963440:rs11230741:rs12362237:rs11604913:rs11230749:rs1624931:rs374377:rs72914272:rs138110361:rs2429862:rs72914277:rs12786457:rs78763563:rs1495941:rs77990365:11:61392884_CA_C:rs72914300:rs762923346;rs72914277:rs1791786:11:61409901_GT_G:rs546240759:rs145786300:rs198435:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs574003650;rs3018326:rs12271414:rs574003650:rs574003650;rs3018327:rs35703574:rs17156254;rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435;rs199969886:11:61445143_AT_A:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs75618234:rs543711028:rs117186302:rs199969886:rs17156254:rs140007352:rs112687416:rs150156331:rs72918076:rs17827918:rs198459:rs149698;rs7935835:11:61742244_CAA_C;rs12576538;rs35686945:rs56215258;rs35686945;rs4963440:rs145379784:rs4963440:rs12576538;rs35686945:rs7935835:rs4963279:rs33972521:rs574832129:rs12576538:rs6591688:rs33972521;rs6591688:11:61800626_CA_C:rs7108589:rs72924290:rs116920297:rs427354:rs199540897:rs759511745:rs259874:rs259873:rs259872:rs77407800:rs11230885:rs4963452:rs259889:rs376224:rs34848597:rs750567872;rs12226389:rs750567872:rs10897211:rs12226389:rs147981159:rs72926113:rs387137",23]
["ENSG00000167992","VWCE",11,61025762,61062896,-1,"protein_coding",220001,"VWCE",{"v":5.90266495568438E-13,"d":"5.90E-13"},-0.457823467,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.7E-281,"d":"5.70E-281"},"rs17762402:rs61896141:rs117110139:rs740006",23]
["ENSG00000124920","MYRF",11,61520114,61555990,1,"protein_coding",745,"MYRF",0.999847803435962,-1.659589693,75,19.93,139,{"v":1.09303E-44,"d":"1.09E-44"},{"v":4.14272e-37,"d":"4.14E-37"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Left_Ventricle:Spleen:IMR90",{"v":5.7E-281,"d":"5.70E-281"},"rs17156254;rs769908354;rs3018327;rs198441;rs117494202;rs198435;rs2238001;rs199969886;rs198422;rs198459;rs9326418;rs77053629;rs198476;rs695186;rs543711028;rs181935125;rs61896137;rs2269928;rs79519287;11:61537648_TG_T;rs174532;rs628993;rs139424418;rs78596000;rs61896141;rs695867;rs509360;rs61747222;rs17762402;rs117110139;rs740006;rs7102974;rs412334;rs174597;rs1495941;rs762923346;rs72914277;rs546240759;rs3018326;rs574003650;rs12271414;rs7116318:rs78596000:rs61896141:rs695867:rs509360:rs61747222:rs174532:rs17762402:rs117110139:rs740006:rs1076180:rs540613:rs35371411:rs2524287:rs2727258:rs174480:rs2736598;rs2727258:rs76133863:rs11230827:rs149037697:rs61895504;rs61893661:rs7943493:rs1627693:rs61893681;rs61895504;rs61893661:rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs11230896:rs12226389;rs71053010:rs750567872;rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs72926147:rs71053010:rs10909647;rs61893681;rs61895504:rs199789685:rs61895504:rs72928167:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs199969886:rs198441:rs769908354;rs3018327:rs75618234:rs543711028:rs117186302:rs199969886:rs17156254:rs140007352:rs112687416:rs150156331:rs72918076:rs574003650;rs3018326:rs17827918:rs198459:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs35703574",23]
["ENSG00000167996","FTH1",11,61727190,61735132,-1,"protein_coding",2495,"FTH1",0.918437494529701,"NA",70,19.26,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-278,"d":"1.40E-278"},"rs2736595;rs2727260;rs112657532;rs2521572;rs183176;rs74556176;rs60517521;rs195161;rs74754540;rs17156580;rs149698;rs56215258;rs4963440;11:61742244_CAA_C;rs111605165;rs35686945;rs71490346;rs117832375;rs2524293:rs74556176:rs74556176;rs60517521:rs2521572:rs74754540:rs2727260:rs2009875:rs195161;rs2736595:rs174481:rs2736595:rs2727260;rs112657532:rs183176:rs111605165:rs149698;rs7935835:rs56215258;rs778782193;rs35686945:rs71490346:11:61742244_CAA_C;rs12576538;rs35686945:rs56215258;rs4963440:rs4343027:rs145379784:rs4963440:rs56215258;rs33972521;rs4963440:rs73493300:rs12576538;rs35686945:rs259889:rs750567872;rs12226389:rs34848597:rs11230885:rs140534658:rs750567872:rs750567872;rs12226389;rs71053010:rs10897211:rs12226389:rs147981159:rs72926113:rs61895466:rs387137:rs116262432:rs259869;rs11230885:rs259869:rs11230896:rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs10909647;rs61893681;rs61895504:rs61895504:rs61895504;rs61893661:rs72928167:rs198435;rs2238001;rs199969886:rs7935835:rs6591688:rs33972521;rs6591688:rs72926147:rs71053010:rs199789685:rs1076180:rs540613:rs35371411:rs2524287:rs2727258:rs174480:rs2736598;rs2727258:rs76133863:rs11230827:rs149037697:rs11230827;rs182407676:rs2736598:rs17156580:rs747321234:rs11825591:rs2524292:rs182407676:rs74556176;rs182407676:rs2727274:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:rs4963279:rs33972521:rs574832129:rs12576538:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908:rs61893681:rs10909647;rs61893681:rs1792909;rs11230920;rs386754192:rs10897232;rs7943493;rs386754192:rs571932724",23]
["ENSG00000269089","AP003733.1",11,61735453,61736755,1,"protein_coding","NA","NA","NA","NA",42,13.73,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-278,"d":"1.40E-278"},"rs195161;rs2736595;rs183176;rs74754540;rs17156580;rs149698;rs56215258;rs4963440;11:61742244_CAA_C;rs111605165;rs60517521;rs74556176;rs35686945;rs71490346;rs117832375;rs4343027;rs76978219;rs2524293:rs74556176:rs74556176;rs60517521:rs2521572:rs74754540:rs2727260:rs2009875:rs195161;rs2736595:rs174481:rs2736595:rs2727260;rs112657532:rs183176:rs111605165:rs149698;rs7935835:rs56215258;rs778782193;rs35686945:rs71490346:11:61742244_CAA_C;rs12576538;rs35686945:rs56215258;rs4963440:rs4343027:rs145379784:rs4963440:rs56215258;rs33972521;rs4963440:rs73493300:rs12576538;rs35686945:rs259889:rs750567872;rs12226389:rs34848597:rs11230885:rs140534658:rs750567872:rs750567872;rs12226389;rs71053010:rs10897211:rs12226389:rs147981159:rs72926113:rs61895466:rs387137:rs116262432:rs259869;rs11230885:rs259869:rs11230896:rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs10909647;rs61893681;rs61895504:rs61895504:rs61895504;rs61893661:rs72928167:rs117186302:rs198435;rs2238001;rs199969886:rs7935835:rs6591688:rs33972521;rs6591688:rs72926147:rs71053010:rs199789685:rs1076180:rs540613:rs35371411:rs2524287:rs2727258:rs174480:rs2736598;rs2727258:rs76133863:rs11230827:rs149037697:rs11230827;rs182407676:rs2736598:rs17156580:rs747321234:rs11825591:rs2524292:rs182407676:rs74556176;rs182407676:rs2727274:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:rs4963279:rs33972521:rs574832129:rs12576538:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908:rs61893681:rs10909647;rs61893681:rs1792909;rs11230920;rs386754192:rs10897232;rs7943493;rs386754192:rs571932724",23]
["ENSG00000124942","AHNAK",11,62201016,62323707,-1,"protein_coding",79026,"AHNAK",0.344567387106657,-0.479742138,1,3.833,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-278,"d":"1.40E-278"},"rs145908530;rs117198764:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000254772","EEF1G",11,62327073,62342401,-1,"protein_coding",1937,"EEF1G",0.998058440819428,-0.553159942,0,0,2,{"v":3.2188e-05,"d":"3.22E-05"},{"v":7.10406E-6,"d":"7.10E-06"},"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-278,"d":"1.40E-278"},"rs73493300;rs61893681;rs61895504;rs61893661:rs1627693:rs7943493:rs72928167:rs11230920:rs61895504;rs61893661:rs116262432:rs7943493;rs1627693:rs61893661:rs117198764:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs145908530:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs174569:rs61896141:rs78596000:rs174597:rs11230803:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000255508","MIR3654",11,62327075,62359003,-1,"protein_coding",100500804,"MIR3654","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-278,"d":"1.40E-278"},"rs145908530:rs117198764:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000149016","TUT1",11,62342517,62359649,-1,"protein_coding",64852,"TUT1",{"v":9.985102139972e-06,"d":"9.99E-06"},-0.411888741,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-278,"d":"1.40E-278"},"rs145908530:rs117198764:rs7102974:rs412334:rs695867:rs117110139:rs75938339:rs2727263:rs138012803:rs75992720;rs78596000:rs695867;rs11230803:rs61897792:rs174569:rs61896141:rs78596000:rs174597:rs11230803:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000204950","LRRC10B",11,61276272,61278482,1,"protein_coding",390205,"LRRC10B","NA",0.211958244,13,10.58,10,{"v":1.04456e-06,"d":"1.04E-06"},0.000864642,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:IMR90",{"v":2.8e-265,"d":"2.80E-265"},"rs7943992;rs71490328;rs2924438;rs3018731:rs198435;rs2238001;rs199969886:rs17156254;rs12271414:rs75618234:rs769908354;rs3018327:rs543711028:rs117186302:rs199969886:rs17156254:rs78596000:rs61896141:rs695867:rs509360:rs61747222:rs174532:rs75992720;rs78596000:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs198435:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs574003650;rs3018326:rs12271414:rs574003650:rs574003650;rs3018327:rs35703574",23]
["ENSG00000149489","ROM1",11,62379194,62382592,1,"protein_coding",6094,"ROM1",0.00326883045590689,"NA",0,0,3,{"v":2.92069E-5,"d":"2.92E-05"},{"v":1.99871e-39,"d":"2.00E-39"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","-","No","NA",{"v":8.8e-170,"d":"8.80E-170"},"rs174468;rs61895466",23]
["ENSG00000006118","TMEM132A",11,60691935,60704631,1,"protein_coding",54972,"TMEM132A",{"v":2.88925822598835e-06,"d":"2.89E-06"},"NA",0,0,3,{"v":1.86449e-05,"d":"1.86E-05"},0.0353944,"GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.3e-105,"d":"1.30E-105"},"rs75992720;rs886264:rs12805902:rs79387516:rs146156958:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs56672345:rs2232143",23]
["ENSG00000149480","MTA2",11,62360686,62369312,-1,"protein_coding",9219,"MTA2",0.978013018375655,0.105631729,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":1.3e-101,"d":"1.30E-101"},"rs17156254:rs769908354;rs3018327:rs769908354:rs198441:rs117494202:rs198435;rs2238001;rs199969886:rs198422:rs198459:rs9326418:rs77053629:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs117198764:rs145908530",23]
["ENSG00000197745","SCGB1D4",11,62063754,62066536,-1,"protein_coding",404552,"SCGB1D4",0.00290219205998929,-0.07411136,1,1.011,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.5e-83,"d":"3.50E-83"},"rs117198764;rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs386754192:rs1792909:rs10897232;rs7943493:rs11230920;rs386754192:rs117198764:rs12806663:rs7936908:rs10897232:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs61893681:rs10909647;rs61893681:rs1792909;rs11230920;rs386754192:rs140534658:rs10897232;rs7943493;rs386754192:rs1076180:rs540613:rs35371411:rs2524287:rs2727258:rs174480:rs2736598;rs2727258:rs76133863:rs11230827:rs149037697:rs11230827;rs182407676:rs2736598:rs17156580:rs747321234:rs11825591:rs2524292:rs182407676:rs74556176;rs182407676:rs2727274:rs2524293:rs74556176:rs74556176;rs60517521:rs2521572:rs74754540:rs2727260:rs2009875:rs195161;rs2736595:rs174481:rs2736595:rs2727260;rs112657532:rs183176:rs112657532:rs195161:rs149698:rs56215258;rs4963440:11:61742244_CAA_C;rs56215258:rs56215258:rs111605165:rs60517521:11:61742244_CAA_C;rs56215258;rs35686945:rs71490346:11:61742244_CAA_C:rs117832375:rs4343027;rs117832375:rs76978219:rs4343027:rs56215258;rs778782193;rs35686945:11:61742244_CAA_C;rs35686945:rs73493300:rs35686945:rs778782193:rs56215258;rs33972521;rs4963440:rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs11230896:rs12226389;rs71053010:rs750567872;rs12226389;rs71053010:11:61854117_GA_G:rs10792328:rs10909647:rs72926147:rs71053010:rs10909647;rs61893681;rs61895504:rs199789685:rs61895504:rs61895504;rs61893661:rs72928167",23]
["ENSG00000255432","RP11-831H9.11",11,62417166,62432650,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.5e-83,"d":"3.50E-83"},"rs117198764:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs145908530:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000162194","C11orf48",11,62430287,62439727,-1,"protein_coding",79081,"C11orf48",{"v":1.53758667829402E-5,"d":"1.54E-05"},0.062299998,0,0,4,{"v":9.9952e-06,"d":"1.00E-05"},{"v":2.14059e-08,"d":"2.14E-08"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.5e-83,"d":"3.50E-83"},"rs259869;rs11230885;rs117198764:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs145908530:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000214756","METTL12",11,62432781,62435968,1,"protein_coding",751071,"METTL12",0.00946026365697049,-0.808107635,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.5e-83,"d":"3.50E-83"},"rs117198764:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs145908530:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000204922","C11orf83",11,62437745,62441159,1,"protein_coding",790955,"C11orf83",0.000546458147219791,-1.075616247,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.5e-83,"d":"3.50E-83"},"rs117198764:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs145908530:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000162191","UBXN1",11,62443970,62446567,-1,"protein_coding",51035,"UBXN1",0.768417510378765,-0.657821788,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.5e-83,"d":"3.50E-83"},"rs695867;rs11230803:rs75992720;rs78596000:rs61897792:rs386754192:rs1792909:rs10897232;rs7943493:rs11230920;rs386754192:rs117198764:rs145908530",23]
["ENSG00000162148","PPP1R32",11,61248592,61258403,1,"protein_coding",220004,"PPP1R32",{"v":2.68242098295629e-07,"d":"2.68E-07"},-0.32639483,21,10.67,2,{"v":7.70395E-5,"d":"7.70E-05"},{"v":6.57508e-14,"d":"6.58E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:IMR90",{"v":2.5e-81,"d":"2.50E-81"},"rs3018731;rs71490328;rs7943992;rs17156254;rs79387516:rs7943992:rs71490328;rs7943992:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs75992720;rs78596000:rs198435:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs574003650;rs3018326:rs12271414:rs574003650:rs574003650;rs3018327:rs35703574",23]
["ENSG00000167986","DDB1",11,61066923,61110068,-1,"protein_coding",1642,"DDB1",0.999992284151209,-1.125296942,2,6.886,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.8e-78,"d":"5.80E-78"},"rs79387516;rs7116318;rs79387516:rs146156958:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908:rs80264062:rs7116318:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs198435:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs574003650;rs3018326:rs12271414:rs574003650:rs574003650;rs3018327:rs35703574:rs78763563:rs17156254;rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435;rs199969886:11:61445143_AT_A:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs75618234:rs543711028:rs117186302:rs199969886:rs17156254:rs140007352:rs112687416:rs150156331:rs72918076:rs17827918:rs198459:rs12805902:rs56672345:rs2232143:rs11230741:rs12362237:rs11604913:rs11230749:rs1624931:rs374377:rs72914272:rs138110361:rs2429862:rs72914277:rs12786457:rs1495941:rs77990365:11:61392884_CA_C:rs72914300:rs1791786",23]
["ENSG00000149476","DAK",11,61100682,61120767,1,"protein_coding",26007,"DAK",{"v":2.79479210875633e-07,"d":"2.79E-07"},-1.078555475,1,8.696,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.8e-78,"d":"5.80E-78"},"rs146156958;rs79387516:rs146156958:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908:rs80264062:rs7116318:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs198435:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs574003650;rs3018326:rs12271414:rs574003650:rs574003650;rs3018327:rs35703574:rs78763563:rs17156254;rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435;rs199969886:11:61445143_AT_A:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs75618234:rs543711028:rs117186302:rs199969886:rs17156254:rs140007352:rs112687416:rs150156331:rs72918076:rs17827918:rs198459:rs12805902:rs56672345:rs2232143:rs11230741:rs12362237:rs11604913:rs11230749:rs1624931:rs374377:rs72914272:rs138110361:rs2429862:rs72914277:rs12786457:rs1495941:rs77990365:11:61392884_CA_C:rs72914300:rs1791786",23]
["ENSG00000011347","SYT7",11,61282785,61348620,-1,"protein_coding",9066,"SYT7",0.904578639335977,"NA",38,19.66,5,{"v":5.73937e-10,"d":"5.74E-10"},{"v":4.42196e-06,"d":"4.42E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":5.8e-78,"d":"5.80E-78"},"rs71490328;rs7943992;rs2924438;rs73496248;rs11230741;rs1794072;rs11604913;rs441938;rs12362237;rs11230749;rs259889;rs79387516:rs71490328;rs7943992:rs71490328:rs7943992:rs11230749:rs1624931:rs12362237:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs17156254:rs198422:rs769908354:rs7116318:rs143699220:rs2924438:rs73496248:rs11230741:rs1794072:rs2924438;rs11604913:rs441938:rs374377:rs72914272:rs138110361:rs2429862:rs72914277:rs12786457:rs1495941:rs77990365:11:61392884_CA_C:rs72914300:rs1791786:rs3018326:rs137915577:rs546240759;rs762923346:rs762923346:rs76376981:rs34915636:rs574003650;rs3018326:rs35703574:rs75618234:rs543711028:rs117186302:rs199969886:rs140007352:rs112687416:rs150156331:rs72918076:rs17827918:rs198459:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908",23]
["ENSG00000214753","HNRNPUL2",11,62480102,62494821,-1,"protein_coding",221092,"HNRNPUL2",0.999925394683505,-1.252192579,0,0,3,{"v":2.79476E-5,"d":"2.79E-05"},0.0249188,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:GM12878",{"v":9e-73,"d":"9.00E-73"},"rs174481;rs149698;rs7935835;rs1792909;rs11230920;rs386754192:rs61893681:rs536206626;rs1627693:rs10897232;rs7943493:rs10909647;rs61893681:rs117198764",23]
["ENSG00000256591","RP11-286N22.8",11,61196692,61253294,1,"protein_coding","NA","NA","NA","NA",21,13.6,5,{"v":7.87139e-06,"d":"7.87E-06"},{"v":1.44416e-05,"d":"1.44E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8e-68,"d":"4.80E-68"},"rs79387516;rs7116318;rs143699220;rs3018731;rs71490328;rs7943992;rs441938;rs2727260;rs75938339;rs146156958:rs79387516:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs71490328;rs7943992:rs71490328:rs7943992",23]
["ENSG00000187049","TMEM216",11,61159159,61166335,1,"protein_coding",51259,"TMEM216",0.00201929498374557,-0.381411902,1,7.051,2,{"v":3.95932e-09,"d":"3.96E-09"},{"v":2.01962E-19,"d":"2.02E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.7e-64,"d":"6.70E-64"},"rs79387516;rs3018731;rs73496248;rs146156958:rs79387516:rs71490328;rs7943992:rs71490328:rs7943992:rs11230741:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs17156254:rs198422:rs769908354:rs12362237:rs11604913:rs12805902:rs56672345:rs2232143:rs80264062:rs7116318:rs143699220",23]
["ENSG00000069482","GAL",11,68451247,68458643,1,"protein_coding",51083,"GAL",2.89003407059731E-4,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8e-57,"d":"4.80E-57"},"rs17601808:rs149402055:rs2229738:rs648336:rs653264:rs648336;rs653264:rs79051613;rs143387014:rs145847523;rs79808713:rs4930630:rs79808713:rs117476044:rs11603763;rs653264:rs11603763",24]
["ENSG00000110090","CPT1A",11,68522088,68611878,-1,"protein_coding",1374,"CPT1A",0.9391397334386,-0.984476778,55,11.71,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8e-57,"d":"4.80E-57"},"rs149402055;rs2229738;rs648336;rs653264;rs79051613;rs143387014;rs648336:rs4930630:rs79051613:rs79808713:rs117476044:rs11603763;rs653264:rs11603763:rs17601808",24]
["ENSG00000197345","MRPL21",11,68658744,68671303,-1,"protein_coding",219927,"MRPL21",{"v":5.45959674014109E-8,"d":"5.46E-08"},-0.421124783,38,17.67,256,{"v":3.45948e-182,"d":"3.46E-182"},{"v":1.1669e-162,"d":"1.17E-162"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.8e-57,"d":"4.80E-57"},"rs648336;rs4930630;rs145847523;rs143387014;rs79051613;rs653264;rs79808713;rs11603763;rs2229738;rs653264:rs648336:rs79051613;rs143387014:rs79808713:rs11603763:rs4930630:rs117476044:rs11603763;rs653264:rs17601808",24]
["ENSG00000132740","IGHMBP2",11,68671310,68708070,1,"protein_coding",3508,"IGHMBP2",{"v":1.5094399423583E-8,"d":"1.51E-08"},-0.168254746,85,19.16,255,{"v":3.83957e-87,"d":"3.84E-87"},{"v":1.10403e-76,"d":"1.10E-76"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.8e-57,"d":"4.80E-57"},"rs648336;rs145847523;rs143387014;rs4930630;rs79051613;rs79808713;rs653264;rs2229738;rs11603763;rs17601808;rs653264:rs648336:rs79051613;rs143387014:rs79808713:rs11603763:rs4930630:rs117476044:rs11603763;rs653264:rs17601808",24]
["ENSG00000172935","MRGPRF",11,68771863,68780877,-1,"protein_coding",116535,"MRGPRF",0.370675550581141,-0.628537393,11,9.077,240,{"v":8.87267e-14,"d":"8.87E-14"},{"v":7.98194e-11,"d":"7.98E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":4.8e-57,"d":"4.80E-57"},"rs4930630;rs11603763;rs653264;rs79808713;rs648336;rs145847523:rs648336:rs143387014:rs17601808:rs149402055:rs2229738:rs653264:rs4930630:rs79051613:rs79808713",24]
["ENSG00000162144","CYB561A3",11,61116217,61129771,-1,"protein_coding",220002,"CYB561A3",0.0587317231678231,-0.713240962,1,8.696,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-45,"d":"1.80E-45"},"rs146156958;rs79387516:rs71490328;rs7943992:rs71490328:rs7943992:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs12362237:rs11604913:rs12805902:rs56672345:rs2232143:rs80264062:rs7116318:rs143699220",23]
["ENSG00000149483","TMEM138",11,61129473,61136981,1,"protein_coding",51524,"TMEM138",0.53112115683539,-0.907267507,1,8.696,1,{"v":4.88517e-06,"d":"4.89E-06"},{"v":2.58071E-6,"d":"2.58E-06"},"GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-45,"d":"1.80E-45"},"rs146156958;rs3018731;rs79387516:rs71490328;rs7943992:rs71490328:rs7943992:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs12805902:rs56672345:rs2232143:rs80264062:rs7116318:rs143699220",23]
["ENSG00000149532","CPSF7",11,61170121,61197503,-1,"protein_coding",79869,"CPSF7",0.991330175057795,-1.553287776,4,7.702,11,{"v":4.56372e-18,"d":"4.56E-18"},{"v":3.52258e-13,"d":"3.52E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-45,"d":"1.80E-45"},"rs80264062;rs7116318;rs79387516;rs146156958;rs3018731;rs259872;rs886264;rs56672345;rs2232143;rs146156958:rs79387516:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs71490328;rs7943992:rs71490328:rs7943992",23]
["ENSG00000167985","SDHAF2",11,61197514,61215001,1,"protein_coding",54949,"SDHAF2",{"v":6.97874038276147E-5,"d":"6.98E-05"},0.630341517,3,13.6,24,{"v":1.79527e-07,"d":"1.80E-07"},{"v":7.13667e-09,"d":"7.14E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-45,"d":"1.80E-45"},"rs79387516;rs7116318;rs1627693;rs536206626;rs10897232;rs7943493;rs1624931;rs146156958:rs79387516:rs762923346;rs72914277:11:61409901_GT_G:rs546240759:rs145786300:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs71490328;rs7943992:rs71490328:rs7943992",23]
["ENSG00000185085","INTS5",11,62414320,62420774,-1,"protein_coding",80789,"INTS5",0.999284368233793,-0.518034449,0,0,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":8.3e-43,"d":"8.30E-43"},"rs198435;rs2238001;rs199969886:rs198476:rs769908354;rs3018327:rs198441:rs198435:rs181935125:rs17156254;rs12271414:rs75618234:rs543711028:rs117186302:rs199969886:rs17156254:rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs117198764:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000177363","LRRN4CL",11,62453874,62457371,-1,"protein_coding",221091,"LRRN4CL",{"v":5.4372145884e-05,"d":"5.44E-05"},-0.63353177,0,0,1,{"v":7.9937e-05,"d":"7.99E-05"},0.0379404,"GTEx/v8/Heart_Atrial_Appendage","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-36,"d":"1.90E-36"},"rs7115739;rs74771917;rs117198764",23]
["ENSG00000110108","TMEM109",11,60681346,60690915,1,"protein_coding",79073,"TMEM109",0.0518905468899636,-0.925977774,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.3E-27,"d":"3.30E-27"},"rs886264:rs12805902:rs146156958:rs79387516:rs78763563:rs17156254;rs12271414:rs12271414:11:61441790_GTGGA_G:rs3018327:rs198435:rs198435;rs199969886:rs574003650;rs3018327:11:61445143_AT_A:rs574003650:rs198435;rs2238001;rs199969886:rs198441:rs769908354;rs3018327:rs56672345:rs2232143",23]
["ENSG00000171533","MAP6",11,75297963,75380165,-1,"protein_coding",4135,"MAP6",0.0131669155399533,-1.145656715,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-24,"d":"2.50E-24"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs72997616;rs10899105;11:75537738_CT_C:rs72997616;rs10899105:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672:11:75553487_CT_C:rs10899105:rs673335:rs72997616;rs28811614:rs117249464:rs72997616;rs28811614:rs190387940:rs12221567:rs28811614:rs72997616:rs72997616;rs12279310:rs7119809:rs12279310",25]
["ENSG00000166391","MOGAT2",11,75428864,75444003,1,"protein_coding",80168,"MOGAT2",0.218649112879292,0.716784085,30,11.19,7,{"v":6.32497E-6,"d":"6.32E-06"},{"v":1.3234e-06,"d":"1.32E-06"},"GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-24,"d":"2.50E-24"},"rs10899105;rs673335;rs72997616;rs28811614;rs117249464;rs673335:rs72997616;rs28811614:rs117249464:rs72997616;rs28811614:rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs72997616;11:75537738_CT_C:rs72997616;rs10899105:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672:11:75553487_CT_C:rs72997616;rs12279310:rs7119809:rs12279310",25]
["ENSG00000162174","ASRGL1",11,62104920,62160882,1,"protein_coding",80150,"ASRGL1",3.86788119196688E-4,0.900304011,2,5.345,4,{"v":3.8989e-06,"d":"3.90E-06"},0.0105131,"GTEx/v8/Heart_Left_Ventricle","-","Yes","Mesendoderm:hESC",{"v":4.6e-24,"d":"4.60E-24"},"rs117198764;rs12806663;rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908",23]
["ENSG00000133316","WDR74",11,62599814,62609281,-1,"protein_coding",54663,"WDR74",{"v":2.46017425068892E-8,"d":"2.46E-08"},1.178952855,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:Trophoblast-like_Cell",{"v":4.6e-24,"d":"4.60E-24"},"rs117198764:rs145908530:rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs11230985:rs7936908",23]
["ENSG00000168003","SLC3A2",11,62623518,62656352,1,"protein_coding",6520,"SLC3A2",0.923234161379885,-0.438386606,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:Trophoblast-like_Cell",{"v":4.6e-24,"d":"4.60E-24"},"rs10897232:rs11230920;rs386754192:rs1792909:rs10897232;rs7943493:rs386754192:rs12806663:rs12806663;rs10897232;rs7943493:rs10897232;rs536206626;rs1627693:rs536206626:rs536206626;rs1627693:rs117198764:rs11230985:rs7936908",23]
["ENSG00000110721","CHKA",11,67820326,67888911,-1,"protein_coding",1119,"CHKA",0.787088146901824,0.439173054,0,0,13,{"v":7.36957e-06,"d":"7.37E-06"},0.0166566,"GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":5e-24,"d":"5.00E-24"},"rs653264;rs648336:rs4930630:rs145847523:rs79808713:rs79051613:rs653264",24]
["ENSG00000132749","MTL5",11,68474908,68519032,-1,"protein_coding",9633,"MTL5",0.0332214023664625,-0.688236883,1,3.036,135,{"v":7.50262e-11,"d":"7.50E-11"},{"v":2.96408e-07,"d":"2.96E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5e-24,"d":"5.00E-24"},"rs149402055;rs648336;rs653264;rs4930630:rs79808713:rs648336:rs79051613:rs653264:rs149402055:rs17601808",24]
["ENSG00000172938","MRGPRD",11,68747490,68748455,-1,"protein_coding",116512,"MRGPRD",4.04522656857286E-4,-0.147839758,34,8.191,186,{"v":5.52149e-15,"d":"5.52E-15"},{"v":2.19138E-29,"d":"2.19E-29"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops",{"v":5e-24,"d":"5.00E-24"},"rs79808713;rs4930630;rs11603763;rs653264;rs648336;rs79051613;rs143387014;rs648336:rs4930630:rs653264:rs117151155:rs145847523",24]
["ENSG00000110092","CCND1",11,69455855,69469242,1,"protein_coding",595,"CCND1",0.238186361767522,-0.876019048,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5e-24,"d":"5.00E-24"},"rs648336:rs4930630:rs145847523:rs79808713:rs79051613:rs653264:rs143387014:rs117476044:rs11603763;rs653264:rs11603763:rs17601808:rs149402055",24]
["ENSG00000168000","BSCL2",11,62457747,62477317,-1,"protein_coding",26580,"BSCL2",0.00852541052442389,-0.902567741,0,0,3,{"v":3.59281e-08,"d":"3.59E-08"},{"v":2.91548e-40,"d":"2.92E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Liver","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-23,"d":"1.40E-23"},"rs7936908;rs145908530;rs35827276;rs117198764",23]
["ENSG00000162337","LRP5",11,68080077,68216743,1,"protein_coding",4041,"LRP5",0.998355570314237,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.5E-23,"d":"1.50E-23"},"rs648336:rs4930630:rs79051613:rs17601808",24]
["ENSG00000110075","PPP6R3",11,68228186,68382802,1,"protein_coding",55291,"PPP6R3",0.995714713640604,0.442037795,4,2.829,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-23,"d":"1.50E-23"},"rs17601808;rs648336:rs4930630:rs79051613:rs17601808:rs149402055",24]
["ENSG00000162341","TPCN2",11,68816365,68858072,1,"protein_coding",219931,"TPCN2",{"v":2.06493806936103e-06,"d":"2.06E-06"},0.177152579,0,0,192,{"v":2.59566e-09,"d":"2.60E-09"},{"v":1.12415e-13,"d":"1.12E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.5E-23,"d":"1.50E-23"},"rs648336;rs4930630;rs11603763;rs79808713;rs653264;rs145847523:rs648336:rs143387014:rs4930630:rs79051613:rs79808713:rs11603763",24]
["ENSG00000149716","ORAOV1",11,69467844,69490184,-1,"protein_coding",220064,"ORAOV1",0.0329902568453812,1.960339439,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":1.5E-23,"d":"1.50E-23"},"rs653264:rs648336:rs79051613;rs143387014:rs4930630:rs79051613:rs79808713:rs11603763:rs117476044:rs11603763;rs653264",24]
["ENSG00000062282","DGAT2",11,75470557,75512579,1,"protein_coding",84649,"DGAT2",{"v":7.51042690362332e-08,"d":"7.51E-08"},-0.634945675,58,13.56,0,"NA","NA","NA","NA","No","NA",{"v":2.7e-22,"d":"2.70E-22"},"rs190387940;rs12221567;rs72997616;rs10899105;rs28811614;rs117249464;rs10899133;11:75539742_GTA_G;11:75537738_CT_C",25]
["ENSG00000110066","SUV420H1",11,67922330,67981295,-1,"protein_coding",51111,"SUV420H1",0.999930189531327,-1.021037424,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-21,"d":"2.10E-21"},"rs17601808:rs149402055",24]
["ENSG00000149243","KLHL35",11,75133438,75141674,-1,"protein_coding",283212,"KLHL35",{"v":1.35038973626761e-12,"d":"1.35E-12"},-0.180877162,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.4e-21,"d":"4.40E-21"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs72997616;rs10899105;11:75537738_CT_C:rs72997616",25]
["ENSG00000198382","UVRAG",11,75526212,75854239,1,"protein_coding",7405,"UVRAG",0.858602500357733,-0.177213177,105,16.46,140,{"v":6.1014e-10,"d":"6.10E-10"},{"v":4.39681e-06,"d":"4.40E-06"},"GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-21,"d":"4.40E-21"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105;11:75537738_CT_C;rs141370279;rs72997672;11:75553487_CT_C;rs12279310;rs7119809;rs28811614;rs190387940;rs7119809:rs12279310:11:75537738_CT_C:rs72997616;rs10899105:rs72997616;11:75537738_CT_C:rs72997616",25]
["ENSG00000085741","WNT11",11,75897369,75921780,-1,"protein_coding",7481,"WNT11",0.118580135382174,-0.390232041,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-21,"d":"4.40E-21"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs72997616;rs10899105;11:75537738_CT_C:rs72997616;rs10899105:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672:11:75553487_CT_C",25]
["ENSG00000137492","PRKRIR",11,76061000,76092015,-1,"protein_coding",5612,"PRKRIR",0.968969189254267,-0.304434935,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.4e-21,"d":"4.40E-21"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs7119809:rs12279310:rs72997616;rs10899105;11:75537738_CT_C:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997616;rs10899105:rs72997672:11:75553487_CT_C",25]
["ENSG00000179240","RP11-111M22.2",11,76092357,76125663,1,"protein_coding",100506127,"GVQW3","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.4e-21,"d":"4.40E-21"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs7119809:rs12279310:rs72997616;rs10899105;11:75537738_CT_C:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997616;rs10899105:rs72997672:11:75553487_CT_C",25]
["ENSG00000137507","LRRC32",11,76368568,76381791,-1,"protein_coding",2615,"LRRC32",0.0215755256662984,1.347358259,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-21,"d":"4.40E-21"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105:rs72997616;rs10899105;11:75537738_CT_C:rs72997616;rs10899105:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672:11:75553487_CT_C",25]
["ENSG00000234857","HNRNPUL2-BSCL2",11,62457747,62494856,-1,"protein_coding",100534595,"HNRNPUL2-BSCL2","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878",{"v":2.3e-20,"d":"2.30E-20"},"rs1792909;rs11230920;rs386754192:rs61893681:rs536206626;rs1627693:rs10897232;rs7943493:rs10909647;rs61893681:rs117198764",23]
["ENSG00000162222","TTC9C",11,62495541,62507765,1,"protein_coding",283237,"TTC9C",0.000139734935043785,-0.148556654,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878",{"v":2.3e-20,"d":"2.30E-20"},"rs1792909;rs11230920;rs386754192:rs61893681:rs536206626;rs1627693:rs10897232;rs7943493:rs10909647;rs61893681:rs117198764",23]
["ENSG00000137486","ARRB1",11,74975226,75062873,-1,"protein_coding",408,"ARRB1",0.986801821116486,-0.49885402,0,0,8,{"v":5.38751e-05,"d":"5.39E-05"},0.0390548,"GTEx/v8/Artery_Aorta","-","Yes","EP_correlation_cell_type_oneway",{"v":2.7E-20,"d":"2.70E-20"},"rs72997616;rs10899133;11:75539742_GTA_G;rs10899105;11:75537738_CT_C",25]
["ENSG00000168569","TMEM223",11,62539101,62559493,-1,"protein_coding",79064,"TMEM223",0.0124355311633348,-0.202932198,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878",{"v":2.6e-19,"d":"2.60E-19"},"rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs386754192:rs1792909:rs10897232;rs7943493:rs11230920;rs386754192:rs117198764",23]
["ENSG00000185475","TMEM179B",11,62554887,62557877,1,"protein_coding",374395,"TMEM179B",0.0107811505009859,0.044347368,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878",{"v":2.6e-19,"d":"2.60E-19"},"rs61895466:rs259869;rs11230885:rs116262432:rs259869:rs386754192:rs1792909:rs10897232;rs7943493:rs11230920;rs386754192:rs117198764",23]
["ENSG00000162344","FGF19",11,69513000,69519410,-1,"protein_coding",9965,"FGF19",0.294076907366963,-0.727218211,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":2.3e-17,"d":"2.30E-17"},"rs648336:rs4930630:rs145847523:rs143387014:rs11603763;rs653264:rs653264:rs79808713:rs11603763:rs117476044",24]
["ENSG00000229859","PGA3",11,60970779,60980570,1,"protein_coding",643834,"PGA3",0.645340633938956,1.444483533,2,2.087,2,{"v":2.71403e-05,"d":"2.71E-05"},0.00268248,"GTEx/v8/Adipose_Visceral_Omentum","-","No","NA",{"v":1.7E-16,"d":"1.70E-16"},"rs56672345;rs9326418",23]
["ENSG00000166889","PATL1",11,59404189,59436453,-1,"protein_coding",219988,"PATL1",0.991973625774226,-0.367218338,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":3.1e-16,"d":"3.10E-16"},"rs146156958:rs79387516:rs71490328;rs7943992:rs71490328:rs7943992:rs80264062:rs7116318",23]
["ENSG00000186895","FGF3",11,69624992,69633792,-1,"protein_coding",2248,"FGF3",0.0330372169885067,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.6e-14,"d":"1.60E-14"},"rs648336:rs4930630:rs653264:rs117151155:rs145847523:rs79808713:rs11603763",24]
["ENSG00000171067","C11orf24",11,68028803,68039469,-1,"protein_coding",53838,"C11orf24",0.0307663209865782,"NA",0,0,2,0.000187489,{"v":7.21112e-47,"d":"7.21E-47"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.3E-14,"d":"2.30E-14"},"rs17601808;rs648336:rs653264:rs17601808",24]
["ENSG00000110107","PRPF19",11,60658202,60674060,-1,"protein_coding",27339,"PRPF19",0.998566695864226,-0.241203742,0,0,1,{"v":1.6336e-05,"d":"1.63E-05"},0.0497184,"GTEx/v8/Artery_Coronary","-","Yes","Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.5e-14,"d":"4.50E-14"},"rs543711028;rs12805902:rs56672345:rs2232143:rs146156958:rs79387516",23]
["ENSG00000256713","PGA5",11,61008514,61018920,1,"protein_coding",5222,"PGA5",1.27358049246854E-3,0.051385651,0,0,2,{"v":2.20291E-6,"d":"2.20E-06"},{"v":7.47517e-12,"d":"7.48E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","No","NA",{"v":2.5e-13,"d":"2.50E-13"},"rs79387516",23]
["ENSG00000166961","MS4A15",11,60524426,60544205,1,"protein_coding",219995,"MS4A15",0.0384681974305748,-0.122458032,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.8E-12,"d":"1.80E-12"},"rs886264:rs12805902:rs56672345:rs2232143:rs146156958:rs79387516",23]
["ENSG00000172689","MS4A10",11,60552821,60568778,1,"protein_coding",341116,"MS4A10",{"v":1.79435429349408e-08,"d":"1.79E-08"},3.123668877,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.8E-12,"d":"1.80E-12"},"rs886264:rs12805902:rs56672345:rs2232143:rs146156958:rs79387516",23]
["ENSG00000110104","CCDC86",11,60609544,60618554,1,"protein_coding",79080,"CCDC86",0.00147735697356089,1.059912771,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":1.8E-12,"d":"1.80E-12"},"rs79387516:rs12805902:rs146156958",23]
["ENSG00000183134","PTGDR2",11,60618413,60623444,-1,"protein_coding",11251,"PTGDR2",0.184110369283718,-0.097335698,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90",{"v":1.8E-12,"d":"1.80E-12"},"rs56672345:rs12805902:rs146156958:rs79387516",23]
["ENSG00000149506","ZP1",11,60635035,60643166,1,"protein_coding",22917,"ZP1",{"v":4.95779407104949E-10,"d":"4.96E-10"},-0.172753153,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90",{"v":1.8E-12,"d":"1.80E-12"},"rs886264:rs12805902:rs146156958:rs79387516",23]
["ENSG00000110448","CD5",11,60869867,60895324,1,"protein_coding",921,"CD5",{"v":2.72798403763384e-05,"d":"2.73E-05"},-1.165038407,3,17.88,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-12,"d":"1.80E-12"},"rs12805902;rs56672345;rs2232143;rs79387516:rs886264:rs12805902:rs56672345:rs2232143:rs146156958",23]
["ENSG00000167987","VPS37C",11,60897728,60929089,-1,"protein_coding",55048,"VPS37C",0.197171487861635,-0.999411993,4,17.88,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.8E-12,"d":"1.80E-12"},"rs12805902;rs56672345;rs2232143;rs12805902:rs79387516:rs146156958:rs56672345:rs2232143",23]
["ENSG00000110243","APOA5",11,116660083,116663136,-1,"protein_coding",116519,"APOA5",{"v":1.37735073361006e-06,"d":"1.38E-06"},0.423730278,2,11.92,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-11,"d":"1.90E-11"},"rs11604424;rs525028:rs11604424",26]
["ENSG00000110245","APOC3",11,116700422,116703788,1,"protein_coding",345,"APOC3",0.00067802640410586,0.121255473,9,8.191,0,"NA","NA","NA","NA","Yes","Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-11,"d":"1.90E-11"},"rs525028",26]
["ENSG00000118137","APOA1",11,116706467,116708666,-1,"protein_coding",335,"APOA1",0.0487383759438174,0.161101272,9,8.191,13,{"v":1.50115e-13,"d":"1.50E-13"},{"v":9.81014e-29,"d":"9.81E-29"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-11,"d":"1.90E-11"},"rs525028",26]
["ENSG00000160584","SIK3",11,116714118,116969153,-1,"protein_coding",23387,"SIK3",0.999882540750175,0.278236341,12,7.526,11,{"v":2.63569e-10,"d":"2.64E-10"},{"v":1.08311e-06,"d":"1.08E-06"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-11,"d":"1.90E-11"},"rs525028;rs525028:rs11604424",26]
["ENSG00000168092","PAFAH1B2",11,117014983,117047610,1,"protein_coding",5049,"PAFAH1B2",0.962029472445706,3.356774148,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-11,"d":"1.90E-11"},"rs11604424:rs525028",26]
["ENSG00000149577","SIDT2",11,117049449,117068160,1,"protein_coding",51092,"SIDT2",0.00257240105871232,-0.315317931,0,0,12,{"v":6.56458e-09,"d":"6.56E-09"},{"v":1.17121e-22,"d":"1.17E-22"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-11,"d":"1.90E-11"},"rs525028;rs11604424:rs525028",26]
["ENSG00000110060","PUS3",11,125763381,125773116,-1,"protein_coding",83480,"PUS3",{"v":1.0865601617407E-5,"d":"1.09E-05"},0.575634337,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-10,"d":"1.10E-10"},"rs78689694",27]
["ENSG00000109832","DDX25",11,125773271,125793158,1,"protein_coding",29118,"DDX25",{"v":4.23433637836541e-09,"d":"4.23E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-10,"d":"1.10E-10"},"rs78689694",27]
["ENSG00000110080","ST3GAL4",11,126225535,126310239,1,"protein_coding",6484,"ST3GAL4",0.439048570873843,-0.027458723,28,12.76,26,{"v":7.88211e-34,"d":"7.88E-34"},{"v":2.54943e-27,"d":"2.55E-27"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","No","NA",{"v":1.1e-10,"d":"1.10E-10"},"rs78689694",27]
["ENSG00000149571","KIRREL3",11,126293254,126873355,-1,"protein_coding",84623,"KIRREL3",0.977505780991965,1.273033827,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-10,"d":"1.10E-10"},"rs78689694",27]
["ENSG00000151702","FLI1",11,128556430,128683162,1,"protein_coding",2313,"FLI1",0.819814084378667,-0.992408347,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.1e-10,"d":"1.10E-10"},"rs78689694",27]
["ENSG00000137656","BUD13",11,116618886,116643704,-1,"protein_coding",84811,"BUD13",2.29542848916745E-3,"NA",2,11.92,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs11604424;rs525028:rs11604424",26]
["ENSG00000109917","ZNF259",11,116648436,116658766,-1,"protein_coding",8882,"ZNF259",0.0193034953229086,0.002394641,2,11.92,1,{"v":5.17357E-5,"d":"5.17E-05"},0.000361971,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs11604424;rs525028:rs11604424",26]
["ENSG00000110244","APOA4",11,116691419,116694022,-1,"protein_coding",337,"APOA4",{"v":3.57595118139907e-05,"d":"3.58E-05"},0.081655096,4,8.191,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"rs525028",26]
["ENSG00000149591","TAGLN",11,117070037,117075498,1,"protein_coding",6876,"TAGLN",0.241537680178233,-0.645790474,0,0,11,{"v":6.90657e-06,"d":"6.91E-06"},{"v":7.71611E-14,"d":"7.72E-14"},"GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs525028;rs525028:rs11604424",26]
["ENSG00000162236","STX5",11,62574369,62599560,-1,"protein_coding",6811,"STX5",0.362948405820287,-0.443811676,0,0,1,{"v":7.59686e-05,"d":"7.60E-05"},0.0297951,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":6.8e-10,"d":"6.80E-10"},"rs116920297",23]
["ENSG00000110446","SLC15A3",11,60704556,60720002,-1,"protein_coding",51296,"SLC15A3",{"v":3.65752302506969e-07,"d":"3.66E-07"},-0.153114642,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.6e-09,"d":"2.60E-09"},"rs56672345:rs7116318:rs79387516:rs12805902:rs2232143",23]
["ENSG00000013725","CD6",11,60739115,60787849,1,"protein_coding",923,"CD6",0.00430465847629855,-0.771889707,0,0,0,"NA","NA","NA","NA","Yes","Spleen:GM12878:IMR90",{"v":2.6e-09,"d":"2.60E-09"},"rs12805902:rs56672345:rs2232143",23]
["ENSG00000268351","AP001888.1",11,69587254,69587718,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.6e-08,"d":"1.60E-08"},"rs648336:rs4930630:rs79808713",24]
["ENSG00000075388","FGF4",11,69587797,69590171,-1,"protein_coding",2249,"FGF4",0.750215677974647,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.6e-08,"d":"1.60E-08"},"rs648336:rs4930630:rs79808713",24]
["ENSG00000166741","NNMT",11,114128509,114184007,1,"protein_coding",4837,"NNMT",0.00427916395502723,-0.273618136,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000180425","C11orf71",11,114262165,114271139,-1,"protein_coding",54494,"C11orf71",0.00842481501256066,-0.124748547,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000076053","RBM7",11,114270752,114284925,1,"protein_coding",10179,"RBM7",0.769935289328386,-0.240422903,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000255663","RP11-212D19.4",11,114271404,114314654,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000076043","REXO2",11,114310108,114321001,1,"protein_coding",25996,"REXO2",0.888428672321779,-0.470637003,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000160613","PCSK7",11,117075053,117103241,-1,"protein_coding",9159,"PCSK7",0.191369613352617,"NA",0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs525028:rs11604424",26]
["ENSG00000167257","RNF214",11,117103341,117157161,1,"protein_coding",257160,"RNF214",0.830018244677536,"NA",0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs525028:rs11604424",26]
["ENSG00000186318","BACE1",11,117156402,117186975,-1,"protein_coding",23621,"BACE1",0.944278809144277,-0.919089932,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000110274","CEP164",11,117185273,117283984,1,"protein_coding",22897,"CEP164",{"v":9.66879225304467e-18,"d":"9.67E-18"},0.753351641,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000254873","RP11-770J1.5",11,118267810,118272610,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000167283","ATP5L",11,118271869,118302211,1,"protein_coding",10632,"ATP5L",0.337891181698725,-0.416063281,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000255384","RP11-770J1.4",11,118303836,118305921,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000118058","KMT2A",11,118307205,118397539,1,"protein_coding",4297,"KMT2A",1,-1.788949198,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8e-08,"d":"1.80E-08"},"rs11604424",26]
["ENSG00000048028","USP28",11,113668596,113746292,-1,"protein_coding",57646,"USP28",0.031657505195455,0.869552466,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.7E-7,"d":"3.70E-07"},"rs11604424",26]
["ENSG00000109906","ZBTB16",11,113930315,114121398,1,"protein_coding",7704,"ZBTB16",0.980087305825708,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.7E-7,"d":"3.70E-07"},"rs11604424",26]
["ENSG00000137491","SLCO2B1",11,74811608,74917594,1,"protein_coding",11309,"SLCO2B1",3.35356336964323E-3,0.050758212,0,0,1,1.11469E-4,0.0450674,"GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":7.5e-07,"d":"7.50E-07"},"rs117249464",25]
["ENSG00000162188","GNG3",11,62475130,62476673,1,"protein_coding",2785,"GNG3",0.5272272299072,-0.216836277,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.9e-06,"d":"4.90E-06"},"rs117198764",23]
["ENSG00000185670","ZBTB3",11,62515791,62521660,-1,"protein_coding",79842,"ZBTB3",0.243280561450218,-0.026467166,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":4.9e-06,"d":"4.90E-06"},"rs117198764",23]
["ENSG00000168002","POLR2G",11,62529016,62534182,1,"protein_coding",5436,"POLR2G",0.00646539515591118,"NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":4.9e-06,"d":"4.90E-06"},"rs117198764",23]
["ENSG00000162227","TAF6L",11,62538775,62554814,1,"protein_coding",10629,"TAF6L",0.819819294441314,6.196699E-3,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":4.9e-06,"d":"4.90E-06"},"rs117198764",23]
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["ENSG00000137871","ZNF280D",15,56922379,57210769,-1,"protein_coding",54816,"ZNF280D",0.820128047448904,-0.120447238,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.2E-37,"d":"1.20E-37"},"rs55760919:rs28690720;rs55760919:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs1560390:rs35717353:rs28690720:rs149299515:rs28690720;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140",29]
["ENSG00000140262","TCF12",15,57210821,57591479,1,"protein_coding",6938,"TCF12",0.973899934245985,-0.962372862,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.2E-37,"d":"1.20E-37"},"rs55760919:rs28690720;rs55760919:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs1560390:rs35717353:rs28690720:rs149299515:rs28690720;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140",29]
["ENSG00000157483","MYO1E",15,59427113,59665099,-1,"protein_coding",4643,"MYO1E",0.0479778930717418,0.925227799,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-37,"d":"1.20E-37"},"rs35924562:rs4774291:rs55760919:rs28690720;rs55760919:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs1560390:rs35717353:rs28690720:rs149299515:rs28690720;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs72739122:rs935213",29]
["ENSG00000157470","FAM81A",15,59664892,59815748,1,"protein_coding",145773,"FAM81A",0.487072320130673,-0.479273207,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-37,"d":"1.20E-37"},"rs35924562:rs4774291:rs55760919:rs28690720;rs55760919:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs1560390:rs35717353:rs28690720:rs149299515:rs28690720;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs72739122:rs935213",29]
["ENSG00000103569","AQP9",15,58430368,58478110,1,"protein_coding",366,"AQP9",0.446614670928057,1.792505109,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Mesendoderm:hESC",{"v":3.6e-13,"d":"3.60E-13"},"rs935213:rs72739189:rs35924562:rs4774291",29]
["ENSG00000137878","GCOM1",15,57884106,58006943,1,"protein_coding",145781,"GCOM1",{"v":3.95491169061382e-09,"d":"3.95E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.2E-8,"d":"1.20E-08"},"rs35924562:rs4774291",29]
["ENSG00000263155","MYZAP",15,57884139,57977562,1,"protein_coding",100820829,"MYZAP",{"v":2.21367341168049e-09,"d":"2.21E-09"},-0.379993748,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.2E-8,"d":"1.20E-08"},"rs35924562:rs4774291",29]
["ENSG00000255529","POLR2M",15,57884231,58074960,1,"protein_coding",81488,"POLR2M",0.169086388609866,-0.26216385,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.2E-8,"d":"1.20E-08"},"rs35924562:rs4774291",29]
["ENSG00000140299","BNIP2",15,59951345,59981733,-1,"protein_coding",663,"BNIP2",{"v":1.6929996956937e-05,"d":"1.69E-05"},3.06677109,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.2E-8,"d":"1.20E-08"},"rs35924562:rs4774291",29]
["ENSG00000168806","LCMT2",15,43619974,43622803,-1,"protein_coding",9836,"LCMT2",{"v":7.26615001081782e-08,"d":"7.27E-08"},-0.138073747,0,0,20,{"v":1.49277E-9,"d":"1.49E-09"},{"v":2.53724e-11,"d":"2.54E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000168803","ADAL",15,43622872,43646096,1,"protein_coding",161823,"ADAL",{"v":8.52495696643507e-09,"d":"8.52E-09"},0.367079509,0,0,20,{"v":3.11018E-12,"d":"3.11E-12"},{"v":1.77353E-83,"d":"1.77E-83"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000067369","TP53BP1",15,43699407,43802926,-1,"protein_coding",7158,"TP53BP1",0.999855964238627,-0.588436209,2,6.298,21,{"v":1.38101E-8,"d":"1.38E-08"},{"v":1.19394E-18,"d":"1.19E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000166963","MAP1A",15,43803156,43823818,1,"protein_coding",4130,"MAP1A",0.999688997602479,-0.820833828,1,19.98,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000242866","STRC",15,43891596,44010458,-1,"protein_coding",161497,"STRC",0.00532184460844672,-0.331251676,2,10.3,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000223572","CKMT1A",15,43985084,43991420,1,"protein_coding",548596,"CKMT1A",0.0141217929367762,-0.865448785,0,0,11,0.00023636,0.0258389,"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000128886","ELL3",15,44064798,44069741,-1,"protein_coding",80237,"ELL3",{"v":3.17480785408243e-06,"d":"3.17E-06"},-0.742052013,0,0,19,{"v":7.11547e-05,"d":"7.12E-05"},{"v":2.53513e-09,"d":"2.54E-09"},"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7E-8,"d":"1.70E-08"},"rs139974673",28]
["ENSG00000159459","UBR1",15,43235095,43398311,-1,"protein_coding",197131,"UBR1",0.319889980799525,-0.76152587,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000166947","EPB42",15,43398423,43513481,-1,"protein_coding",2038,"EPB42",{"v":1.56180488450141e-07,"d":"1.56E-07"},-0.595710426,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000104055","TGM5",15,43524793,43559055,-1,"protein_coding",9333,"TGM5",{"v":5.36528605073887E-16,"d":"5.37E-16"},-0.136771588,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000140265","ZSCAN29",15,43650370,43663223,-1,"protein_coding",146050,"ZSCAN29",{"v":2.29379256843049e-06,"d":"2.29E-06"},-1.044556633,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000137822","TUBGCP4",15,43661419,43699293,1,"protein_coding",27229,"TUBGCP4",0.00528348188155799,-0.843870096,5,14.3,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000168781","PPIP5K1",15,43825660,43882430,-1,"protein_coding",9677,"PPIP5K1",0.102604913232572,-0.983223441,1,19.98,4,0.000208914,0.0478915,"GTEx/v8/Adipose_Visceral_Omentum","+","No","NA",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000167004","PDIA3",15,44038590,44065477,1,"protein_coding",2923,"PDIA3",0.959251419181895,-0.294235316,0,0,4,2.01614E-4,1.55857E-3,"GTEx/v8/Heart_Atrial_Appendage","+","No","NA",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000140264","SERF2",15,44069285,44094787,1,"protein_coding",10169,"SERF2",0.138975962472976,-0.560226742,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000268488","AC018512.1",15,44075041,44075231,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-08,"d":"2.30E-08"},"rs139974673",28]
["ENSG00000140326","CDAN1",15,43015757,43029324,-1,"protein_coding",146059,"CDAN1",0.928144193175439,-0.233969905,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs139974673",28]
["ENSG00000159495","TGM7",15,43568478,43594453,-1,"protein_coding",116179,"TGM7",{"v":6.34381866870598e-10,"d":"6.34E-10"},-0.076725641,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.4E-8,"d":"2.40E-08"},"rs139974673",28]
["ENSG00000166762","CATSPER2",15,43920701,43960316,-1,"protein_coding",117155,"CATSPER2",{"v":3.0443890998245e-05,"d":"3.04E-05"},"NA",2,10.3,0,"NA","NA","NA","NA","No","NA",{"v":1.6E-7,"d":"1.60E-07"},"rs139974673",28]
["ENSG00000171877","FRMD5",15,44162962,44487450,-1,"protein_coding",84978,"FRMD5",0.991843164486017,-1.541636281,8,15.34,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6E-7,"d":"1.60E-07"},"rs139974673",28]
["ENSG00000137877","SPTBN5",15,42140345,42186275,-1,"protein_coding",51332,"SPTBN5",{"v":1.09010380481407e-70,"d":"1.09E-70"},0.338139096,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2e-07,"d":"2.00E-07"},"rs139974673",28]
["ENSG00000242028","HYPK",15,44088340,44095241,1,"protein_coding",25764,"HYPK",0.021030750002461,-0.443035584,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2e-07,"d":"2.00E-07"},"rs139974673",28]
["ENSG00000166734","CASC4",15,44580927,44707956,1,"protein_coding",113201,"CASC4",0.000967729828290193,-1.716637278,2,16.39,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.6e-07,"d":"7.60E-07"},"rs139974673",28]
["ENSG00000104131","EIF3J",15,44829255,44855227,1,"protein_coding",8669,"EIF3J",0.859084260110388,-0.525168639,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.6e-07,"d":"7.60E-07"},"rs139974673",28]
["ENSG00000137770","CTDSPL2",15,44719432,44821236,1,"protein_coding",51496,"CTDSPL2",0.995978213604988,-2.709896183,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1e-06,"d":"1.00E-06"},"rs139974673",28]
["ENSG00000140263","SORD",15,45315302,45369383,1,"protein_coding",6652,"SORD",4.34794621162012E-3,-0.211294181,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.7E-6,"d":"2.70E-06"},"rs139974673",28]
["ENSG00000104133","SPG11",15,44854894,44955876,-1,"protein_coding",80208,"SPG11",{"v":2.91203449273578E-22,"d":"2.91E-22"},-0.610414505,2,5.908,0,"NA","NA","NA","NA","No","NA",{"v":5.2e-06,"d":"5.20E-06"},"rs139974673",28]
["ENSG00000229474","PATL2",15,44957930,45003514,-1,"protein_coding",197135,"PATL2",0.0677100893702347,0.105561141,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-06,"d":"5.20E-06"},"rs139974673",28]
["ENSG00000166710","B2M",15,45003675,45011075,1,"protein_coding",567,"B2M",0.856561948026764,0.154210813,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-06,"d":"5.20E-06"},"rs139974673",28]
["ENSG00000185880","TRIM69",15,45021186,45060027,1,"protein_coding",140691,"TRIM69",{"v":1.96411504084879e-10,"d":"1.96E-10"},0.017868058,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-06,"d":"5.20E-06"},"rs139974673",28]
["ENSG00000103512","NOMO1",16,14927538,14990017,1,"protein_coding",23420,"NOMO1","NA",-0.55803402,13,12.9,80,{"v":3.09949e-10,"d":"3.10E-10"},{"v":2.74226e-15,"d":"2.74E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell",{"v":1.2e-70,"d":"1.20E-70"},"rs370260133;rs572006137;rs141502961;rs538834547;rs71374758;rs11644601;rs3198697;rs62039478;rs374889059;rs2307502;rs153799;rs2519438;rs35512524;rs72789541;rs755903303;rs34955778;rs11075260;rs8054081;16:15640870_CT_C;rs559115405;rs56826720;rs3867518;rs11075261;rs56006013;rs222140;rs35694612;rs2384934;rs377615530;rs222140:rs774936434:rs538834547:rs34376746:rs35694612;rs377615530:rs117876551:rs62039124;rs34376746;rs880071:rs35694612:rs4781684:rs62039124;rs880071:rs880071:rs377615530",30]
["ENSG00000183426","NPIPA1",16,15016659,15045915,1,"protein_coding",9284,"NPIPA1",0.495053838627117,-0.152307969,5,2.895,356,{"v":2.27979e-39,"d":"2.28E-39"},{"v":4.30601e-32,"d":"4.31E-32"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":1.2e-70,"d":"1.20E-70"},"rs3198697;rs4985127;rs35429473;rs528780951;rs34483003;rs559115405;rs56826720;rs71373034;16:14648291_AT_A;rs34936342;rs2519438;rs62039478;rs370260133;rs141502961;rs572006137;rs538834547;rs374889059;rs35512524;rs72789541;rs755903303;rs11644601;rs8048552;rs11075260;rs11861982;rs11075261;rs3867518;rs56006013;rs199782954;rs62037794;rs61084260;rs140014347;rs2307502;rs153799;rs774936434;rs8053048;rs222140;rs1684546;rs766485929;16:15598635_TA_T;rs62039124;16:15640870_CT_C;rs34072053;rs34376746;rs35694612;rs880071;rs377615530;rs4781684;rs2384934;rs148348041;rs148664265;rs111618101;rs188533455;rs117975403;rs58837030;rs147627332",30]
["ENSG00000179889","PDXDC1",16,15068448,15233196,1,"protein_coding",23042,"PDXDC1",{"v":2.30260183441473e-07,"d":"2.30E-07"},-0.437005006,108,22.7,176,{"v":3.10265e-25,"d":"3.10E-25"},{"v":1.00609e-19,"d":"1.01E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs200575134;rs529360800;rs72789541;rs62039478;rs35512524;rs4985127;rs148664265;rs71374758;rs9928601;rs28412131;rs374889059;rs9888789;rs755903303;rs3198697;rs34955778;rs11644601;rs188533455;rs35429473;rs8048552;rs538834547;rs148348041;rs34483003;rs71373034;rs34936342;rs11075260;rs11861982;rs8054081;16:15414730_CTTTTTTTTTT_C;rs139110024;rs75512281;rs140014347;rs153799;rs62039124;rs572006137;rs34376746;rs880071;rs4781684;16:14591093_CT_C;rs111618101;rs55900631;rs2519438;rs199782954;rs141502961;rs11075261;rs3867518;rs56006013;rs1684546;rs35694612;rs377615530;rs8048552:rs62039478:rs35512524:rs538834547:rs528066129:rs34072053:rs72789541;rs755903303:rs72789541:rs3198697:rs34955778:rs755903303:rs11644601:rs188533455:rs1684546;16:15598635_TA_T;rs58837030:rs1684546;16:15598635_TA_T:rs58837030:16:15598635_TA_T:rs1684546:rs148991560:rs62039124:rs117975403:rs222140:16:15640870_CT_C:16:15635759_TA_T:rs4985127:rs148664265:rs71374758:rs9928601:rs28412131:rs374889059:rs9888789:rs34376746:rs35694612;rs377615530:rs377615530:rs35694612:rs61084260:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs774936434;rs8053048:rs774936434:rs153799:rs1684546;rs774936434:rs766485929:rs36058330:rs555987464:rs117876551:rs62039124;rs880071:rs62039124;rs880071:rs4781684:rs2384934;rs35694612:rs880071:rs2384934",30]
["ENSG00000157045","NTAN1",16,15131710,15149921,-1,"protein_coding",123803,"NTAN1",0.0158736622184606,"NA",52,22.7,67,{"v":2.21296e-14,"d":"2.21E-14"},{"v":7.68744e-10,"d":"7.69E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs72789541;rs755903303;rs35512524;rs62039478;rs3198697;rs34955778;rs11644601;rs188533455;rs199782954;rs35429473;rs11075260;rs11075261;rs3867518;rs56006013;rs2519438;rs2384934;rs111618101;rs8048552;rs528780951;rs148664265;rs117876551;rs572006137;rs141502961;rs538834547;rs222140;rs35694612;rs377615530;rs62039478:rs374889059:rs148664265:rs538834547:rs35512524:rs72789541;rs755903303:rs72789541:rs34955778:rs3198697:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:16:15640870_CT_C:rs62039124:rs34072053:rs34376746:rs117876551:rs35694612;rs377615530:rs377615530:rs35694612:rs62039124;rs34376746;rs880071:rs62039124;rs880071:rs71374758:rs9928601:rs28412131:rs9888789:rs61084260:rs188533455:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs1684546;16:15598635_TA_T;rs58837030:rs1684546;16:15598635_TA_T:rs58837030:16:15598635_TA_T:rs1684546:rs148991560:rs117975403:rs222140:16:15635759_TA_T:rs880071",30]
["ENSG00000085721","RRN3",16,15153879,15188174,-1,"protein_coding",54700,"RRN3",0.000474580439094432,-0.668988091,24,6.506,83,{"v":9.54152e-09,"d":"9.54E-09"},{"v":8.06072e-24,"d":"8.06E-24"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops",{"v":1.2e-70,"d":"1.20E-70"},"rs72789541;rs755903303;rs11644601;rs62039478;rs188533455;rs35429473;rs8048552;rs35512524;rs148664265;rs538834547;rs4781684;rs3198697;rs11075260;rs117876551;rs62036306;rs111618101;rs3867518;rs11075261;rs56006013;rs2519438;rs199782954;rs2384934;rs8053048;rs111618101:rs34936342:rs56826720:rs62039478:rs374889059:rs529360800:rs188533455:rs35512524:rs538834547",30]
["ENSG00000183793","NPIPA5",16,15457516,15474904,-1,"protein_coding",100288332,"NPIPA5",0.544994923114436,-0.083296396,6,2.546,397,{"v":2.49656E-61,"d":"2.50E-61"},{"v":1.0127E-51,"d":"1.01E-51"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":1.2e-70,"d":"1.20E-70"},"rs61084260;rs141502961;rs572006137;rs75512281;rs140014347;rs9941229;rs34483003;rs559115405;rs56826720;rs71373034;16:14648291_AT_A;rs34936342;rs111618101;rs146651998;rs62039478;rs370260133;rs538834547;rs3198697;rs374889059;rs35429473;rs35512524;rs148664265;rs72789541;rs755903303;rs11644601;rs8048552;rs188533455;rs11075260;rs11861982;rs3867518;rs11075261;rs56006013;rs2519438;rs199782954;rs62037794;rs2307502;rs153799;rs774936434;rs222140;rs1684546;rs62039124;16:15598635_TA_T;rs117975403;rs34072053;rs34376746;rs35694612;rs377615530;rs880071;rs4781684;rs2384934;rs148348041;16:14591093_CT_C;rs139110024;rs62036306;rs117876551;rs147627332;rs1684546:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs117975403:rs222140:16:15640870_CT_C:16:15635759_TA_T:rs148991560:rs62039124:rs35694612;rs377615530:rs34376746:rs377615530",30]
["ENSG00000261130","RP11-1021N1.1",16,15489611,15609205,1,"protein_coding","NA","NA","NA","NA",114,12.74,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs61084260;rs188533455;rs2307502;rs141502961;rs153799;rs8053048;rs774936434;rs222140;rs538834547;rs1684546;rs766485929;rs36058330;16:15598635_TA_T;rs555987464;rs62039124;rs58837030;rs148991560;rs62039478:rs374889059:rs4781684:rs62039124;rs880071:rs1684546;rs58837030:rs1684546;16:15598635_TA_T:rs58837030:16:15598635_TA_T:rs1684546:rs148991560:rs62039124:rs117975403:rs222140:16:15640870_CT_C:16:15635759_TA_T:rs35694612:rs62039124;rs34376746;rs880071:rs35694612;rs377615530:rs377615530:rs880071:rs34072053:rs34376746:rs117876551:rs199782954:rs3198697:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs72789541:rs72789541;rs755903303:rs35512524:rs34955778:rs755903303:rs11644601:rs188533455:rs774936434;rs8053048:rs8053048:rs774936434:rs141502961:rs153799:rs538834547:rs1684546;rs774936434:rs766485929:rs36058330:rs555987464:rs2384934;rs35694612:rs2384934",30]
["ENSG00000156968","MPV17L",16,15489611,15507125,1,"protein_coding",255027,"MPV17L",0.000500982038571006,-0.394011201,11,4.787,126,{"v":2.22013e-28,"d":"2.22E-28"},{"v":3.01833e-39,"d":"3.02E-39"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs61084260;rs188533455;rs2307502;rs141502961;rs153799;rs8053048;16:14591093_CT_C;rs528780951;rs148664265;rs139110024;rs774936434;rs222140;rs1684546;rs766485929;rs62039124;16:15598635_TA_T;rs34376746;rs117876551;rs880071;rs35429473;rs8048552;rs62039478:rs374889059:rs4781684:rs62039124;rs880071:rs1684546;rs58837030:rs1684546;16:15598635_TA_T:rs58837030:16:15598635_TA_T:rs1684546:rs148991560:rs62039124:rs117975403:rs222140:16:15640870_CT_C:16:15635759_TA_T:rs35694612:rs62039124;rs880071:rs35694612;rs377615530:rs377615530:rs880071:rs34072053:rs34376746:rs117876551:rs199782954:rs3198697:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs72789541:rs72789541;rs755903303:rs35512524:rs34955778:rs755903303:rs11644601:rs188533455:rs774936434;rs8053048:rs8053048:rs774936434:rs141502961:rs153799:rs538834547:rs1684546;rs774936434:rs766485929:rs36058330:rs555987464:rs2384934;rs35694612:rs2384934",30]
["ENSG00000166783","KIAA0430",16,15688243,15737023,-1,"protein_coding",9665,"KIAA0430",0.999999565958546,-1.509457287,42,19.19,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs34376746;rs35694612;rs377615530;rs117876551;rs62039124;rs880071;16:15640870_CT_C:rs62039124:rs34072053:rs34376746:rs117876551:rs35694612;rs377615530:rs377615530:rs35694612:rs72789541;rs755903303:rs35512524:rs62039478:rs72789541:rs3198697:rs34955778:rs755903303:rs11644601:rs188533455:rs61084260:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs1684546:rs766485929:rs36058330:rs222140:rs1684546;16:15598635_TA_T:rs555987464:rs1684546;16:15598635_TA_T;rs58837030:16:15598635_TA_T:rs58837030:rs148991560:rs117975403:16:15635759_TA_T:rs62039124;rs880071:rs62039124;rs880071:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs148664265:rs71374758:rs9928601:rs28412131:rs374889059:rs9888789",30]
["ENSG00000072864","NDE1",16,15737124,15820210,1,"protein_coding",54820,"NDE1",0.0471095482859516,0.252883746,45,22.5,38,{"v":7.57097e-25,"d":"7.57E-25"},{"v":2.09062e-21,"d":"2.09E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs34376746;rs35694612;rs377615530;rs117876551;rs62039124;rs880071;rs4781684;rs62039478;rs71374758;rs11644601;rs11075260;rs2384934;rs55900631;rs35512524;rs11861982;16:15640870_CT_C:rs62039124:rs34072053:rs34376746:rs117876551:rs35694612;rs377615530:rs377615530:rs35694612:rs72789541;rs755903303:rs35512524:rs62039478:rs72789541:rs3198697:rs34955778:rs755903303:rs11644601:rs188533455:rs61084260:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs1684546:rs766485929:rs36058330:rs222140:rs1684546;16:15598635_TA_T:rs555987464:rs1684546;16:15598635_TA_T;rs58837030:16:15598635_TA_T:rs58837030:rs148991560:rs117975403:16:15635759_TA_T:rs62039124;rs880071:rs62039124;rs880071:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs148664265:rs71374758:rs9928601:rs28412131:rs374889059:rs9888789",30]
["ENSG00000133392","MYH11",16,15797029,15950890,-1,"protein_coding",4629,"MYH11",0.998956488496709,-1.803748E-3,59,22.5,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs62039124;rs34376746;rs880071;rs35694612;rs4781684;rs377615530;rs2384934;rs117876551;rs880071:rs117876551:rs377615530:rs4781684:rs3198697:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs72789541:rs62039478:rs72789541;rs755903303:rs35512524:rs34955778:rs755903303:rs11644601:rs188533455:16:15640870_CT_C:rs62039124:rs34072053:rs34376746:rs35694612;rs377615530:rs35694612:rs62039124;rs880071:rs62039124;rs880071:rs2384934;rs35694612:rs2384934:rs61084260:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs1684546;16:15598635_TA_T;rs58837030:rs1684546;16:15598635_TA_T:rs58837030:16:15598635_TA_T:rs1684546:rs148991560:rs117975403:rs222140:16:15635759_TA_T",30]
["ENSG00000133393","FOPNL",16,15959577,15982482,-1,"protein_coding",123811,"FOPNL",{"v":9.46709362306996e-06,"d":"9.47E-06"},1.986607342,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2e-70,"d":"1.20E-70"},"rs35512524:rs538834547:rs528066129:rs72789541;rs755903303:rs62039478:rs72789541:rs3198697:rs34955778:rs755903303:rs11644601:rs188533455:rs880071:rs117876551:rs377615530:rs4781684:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs61084260:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs35694612:rs62039124;rs880071:rs2384934;rs35694612:rs2384934",30]
["ENSG00000254852","NPIPA2",16,14841923,14859270,1,"protein_coding",642799,"NPIPA2","NA",-0.137549156,5,2.922,57,{"v":4.75708e-10,"d":"4.76E-10"},{"v":2.41318e-09,"d":"2.41E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","No","NA",{"v":6.6e-59,"d":"6.60E-59"},"rs4003231;rs146651998;rs200324553;rs55900631;rs370260133;rs3198697;rs374889059;rs11644601;rs11075260;rs62039124;rs35694612;rs34376746;rs880071;rs4781684;rs2384934;rs35429473;rs8048552;rs141502961;rs572006137;rs222140",30]
["ENSG00000069764","PLA2G10",16,14766405,14788526,-1,"protein_coding",8399,"PLA2G10",0.0217477326167779,-0.612986857,6,3.887,1,{"v":5.06613e-05,"d":"5.07E-05"},0.00873002,"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":7.6e-58,"d":"7.60E-58"},"rs111618101;rs34936342;rs56826720;rs188533455;16:14591093_CT_C;rs55900631;rs35512524;rs111618101:rs34936342:rs56826720:rs11644601",30]
["ENSG00000166780","C16orf45",16,15528152,15718885,1,"protein_coding",89927,"C16orf45",0.214680178058486,-0.633435445,171,19.19,90,{"v":1.57234e-10,"d":"1.57E-10"},{"v":1.56637E-6,"d":"1.57E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.9E-50,"d":"1.90E-50"},"rs774936434;rs8053048;rs222140;rs141502961;rs153799;rs538834547;rs1684546;rs766485929;rs36058330;16:15598635_TA_T;rs555987464;rs62039124;rs58837030;rs148991560;rs117975403;16:15640870_CT_C;16:15635759_TA_T;rs34072053;rs34376746;rs117876551;rs35694612;rs377615530;rs2307502;rs34376746:rs35694612:rs35694612;rs377615530:rs377615530:rs3198697:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs72789541:rs62039478:rs61084260:rs188533455:rs2307502:rs141502961:rs153799;rs2307502:rs8053048:rs1684546;rs58837030:rs1684546;16:15598635_TA_T:rs58837030:16:15598635_TA_T:rs1684546:rs148991560:rs62039124:rs117975403:rs222140:16:15640870_CT_C:16:15635759_TA_T:rs34072053:rs117876551",30]
["ENSG00000091262","ABCC6",16,16242785,16317379,-1,"protein_coding",368,"ABCC6",{"v":1.4545670403957E-6,"d":"1.45E-06"},1.25585067,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9E-50,"d":"1.90E-50"},"rs774936434;rs8053048:rs8053048:rs222140:rs774936434:rs141502961:16:15598635_TA_T:rs117975403:16:15640870_CT_C:16:15635759_TA_T:rs148991560:rs62039124:rs35694612:rs4781684:rs62039124;rs880071:rs62039124;rs34376746;rs880071:rs35694612;rs377615530:rs880071:rs117876551:rs377615530:rs3198697:rs4985127:rs35429473:rs528780951:rs200575134:rs529360800:rs72789541:rs62039478:rs34376746",30]
["ENSG00000103226","NOMO3",16,16326352,16388668,1,"protein_coding",408050,"NOMO3","NA",-0.391240572,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.7e-27,"d":"5.70E-27"},"rs188533455:rs61084260:rs2307502:rs141502961",30]
["ENSG00000140694","PARN",16,14529558,14726585,-1,"protein_coding",5073,"PARN",0.387183623172132,-0.956619677,125,14.45,6,{"v":1.31831E-6,"d":"1.32E-06"},{"v":8.00184e-05,"d":"8.00E-05"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops",{"v":2.7e-25,"d":"2.70E-25"},"rs62036306;rs559115405;rs56826720;rs147627332;16:14648291_AT_A;rs148348041;rs34483003;16:14591093_CT_C;rs71373034;16:14647113_TAA_T;rs34936342;rs111618101;rs55900631;rs538834547:rs71374758:rs11075261:rs11075261;rs56006013:rs11861982:rs56006013",30]
["ENSG00000103429","BFAR",16,14726672,14763093,1,"protein_coding",51283,"BFAR",0.00230974824450457,-0.464762609,12,19.04,27,{"v":5.05297E-8,"d":"5.05E-08"},{"v":6.4824e-05,"d":"6.48E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":2.7e-25,"d":"2.70E-25"},"rs559115405;16:14648291_AT_A;rs56826720;rs34936342;rs62036306;rs111618101;rs11075260;rs538834547:rs71374758:rs11075261:rs11075261;rs56006013:rs11861982:rs56006013",30]
["ENSG00000153066","TXNDC11",16,11772936,11836734,-1,"protein_coding",51061,"TXNDC11",0.00317800786829343,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.7e-24,"d":"4.70E-24"},"rs559115405;16:14648291_AT_A;rs56826720:rs559115405;rs147627332;rs56826720:rs559115405:rs71373034:rs148348041:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342",30]
["ENSG00000171490","RSL1D1",16,11929056,11945442,-1,"protein_coding",26156,"RSL1D1",0.000364294182041933,-0.233303564,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.7e-24,"d":"4.70E-24"},"rs559115405;16:14648291_AT_A;rs56826720:rs34483003:rs559115405;rs56826720:16:14647113_TAA_T:16:14648291_AT_A:rs71373034:rs559115405:rs34936342",30]
["ENSG00000237515","SHISA9",16,12995477,13334272,1,"protein_coding",729993,"SHISA9","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.7e-24,"d":"4.70E-24"},"rs62036306:rs559115405;rs56826720:rs559115405;rs147627332;16:14648291_AT_A;rs56826720:rs559115405:rs148348041:rs559115405;16:14648291_AT_A:rs559115405;rs56826720:rs71373034:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342",30]
["ENSG00000175595","ERCC4",16,14014014,14046202,1,"protein_coding",2072,"ERCC4",{"v":3.33157717442271e-10,"d":"3.33E-10"},1.194015475,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.7e-24,"d":"4.70E-24"},"rs559115405;16:14648291_AT_A;rs56826720:rs559115405;rs56826720:rs71373034:rs148348041:rs62036306:rs559115405;rs147627332;rs56826720:rs559115405:rs559115405;16:14648291_AT_A:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342:rs147627332:rs10048117:rs9941229:rs111618101:rs559115405;16:14648291_AT_A:16:14591093_CT_C:rs56826720:rs62036306;rs111618101",30]
["ENSG00000186260","MKL2",16,14165178,14360630,1,"protein_coding",57496,"MKL2",0.999938115504898,0.374779713,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.7e-24,"d":"4.70E-24"},"rs559115405;16:14648291_AT_A;rs56826720:rs559115405;rs147627332;rs56826720:rs559115405:rs71373034:rs148348041:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342:rs62036306:rs559115405;16:14648291_AT_A:rs559115405;16:14648291_AT_A:16:14591093_CT_C:rs147627332:rs10048117:rs9941229:rs111618101",30]
["ENSG00000269049","AC092291.2",16,14564842,14565054,1,"protein_coding","NA","NA","NA","NA",7,10.02,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.7e-24,"d":"4.70E-24"},"rs559115405;16:14648291_AT_A;rs56826720;rs147627332;rs62036306:rs559115405;rs56826720:rs559115405;rs56826720:rs559115405:rs148348041:rs559115405;16:14648291_AT_A:rs559115405;rs56826720:rs71373034:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342:rs147627332:rs10048117:rs9941229:rs111618101",30]
["ENSG00000184602","SNN",16,11762270,11773015,1,"protein_coding",8303,"SNN",0.0202490590604754,0.972465844,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.8e-23,"d":"4.80E-23"},"rs62036306:rs559115405;rs56826720:rs559115405;rs147627332;16:14648291_AT_A;rs56826720:rs559115405:rs148348041:rs559115405;16:14648291_AT_A:rs559115405;rs56826720:rs71373034",30]
["ENSG00000103489","XYLT1",16,17195626,17564738,-1,"protein_coding",64131,"XYLT1",0.985159711217428,2.939790489,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.8e-23,"d":"4.80E-23"},"rs559115405;16:14648291_AT_A;rs56826720:rs559115405;rs147627332;rs56826720:rs559115405:rs71373034:rs148348041",30]
["ENSG00000087253","LPCAT2",16,55542910,55620582,1,"protein_coding",54947,"LPCAT2",{"v":1.12519142457894e-06,"d":"1.13E-06"},1.042935368,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000159461","AMFR",16,56395364,56459450,-1,"protein_coding",267,"AMFR",0.00142575921262617,-0.148588909,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000167005","NUDT21",16,56463045,56486111,-1,"protein_coding",11051,"NUDT21",0.947296445770822,-0.951045808,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000087263","OGFOD1",16,56485402,56513012,1,"protein_coding",55239,"OGFOD1",{"v":1.29448940600909E-8,"d":"1.29E-08"},1.038879494,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000102891","MT4",16,56598961,56602869,1,"protein_coding",84560,"MT4",0.0079945846958122,0.168441799,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000087250","MT3",16,56622986,56625000,1,"protein_coding",4504,"MT3",0.254133469605707,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000125148","MT2A",16,56642111,56643409,1,"protein_coding",4502,"MT2A",0.0538691874978182,-0.424007583,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000169715","MT1E",16,56659387,56661024,1,"protein_coding",4493,"MT1E",0.659212996447356,-0.089953071,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000268317","AC026461.1",16,56662971,56666150,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000205364","MT1M",16,56666145,56667898,1,"protein_coding",4499,"MT1M",{"v":9.83543934507332e-05,"d":"9.84E-05"},-0.29422965,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000205362","MT1A",16,56672578,56673999,1,"protein_coding",4489,"MT1A",0.0077761859390121,0.386134236,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000169688","MT1B",16,56685811,56687116,1,"protein_coding",4490,"MT1B",0.248269442186515,0.35296703,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000198417","MT1F",16,56691606,56694610,1,"protein_coding",4494,"MT1F",0.0538496988016702,-0.344970169,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000125144","MT1G",16,56700643,56701977,-1,"protein_coding",4495,"MT1G",0.00811948407601034,0.102812001,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000205358","MT1H",16,56703726,56705041,1,"protein_coding",4496,"MT1H",0.0548412149416522,-0.294410812,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000187193","MT1X",16,56716336,56718108,1,"protein_coding",4501,"MT1X",0.0496111915968201,0.296377401,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000102900","NUP93",16,56764017,56878797,1,"protein_coding",9688,"NUP93",4.86804388235231E-3,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000070915","SLC12A3",16,56899119,56949762,1,"protein_coding",6559,"SLC12A3",{"v":5.54410952233344e-18,"d":"5.54E-18"},1.058293826,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224:rs118146573:rs9939224:rs11076176",31]
["ENSG00000051108","HERPUD1",16,56965960,56977798,1,"protein_coding",9709,"HERPUD1",0.82104286595303,-0.272869343,8,6.618,8,{"v":7.44854e-07,"d":"7.45E-07"},{"v":9.20685e-07,"d":"9.21E-07"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419;rs3764261;rs12448528;rs12923459;rs9989419:rs3764261:rs12448528:rs12923459:rs1864163;rs9939224:rs118146573:rs3816117:rs9939224:rs11076176",31]
["ENSG00000087237","CETP",16,56995762,57017757,1,"protein_coding",1071,"CETP",{"v":5.18056762742226e-12,"d":"5.18E-12"},0.043908821,50,14.68,28,{"v":2.31346E-8,"d":"2.31E-08"},{"v":7.55584e-05,"d":"7.56E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.6e-20,"d":"3.60E-20"},"rs12923459;rs3764261;rs12708967;rs12720918;rs3816117;rs1864163;rs9939224;rs118146573;rs11076176;rs9939224:rs118146573:rs3816117:rs3764261:rs9939224:rs11076176",31]
["ENSG00000140853","NLRC5",16,57023397,57117443,1,"protein_coding",84166,"NLRC5",{"v":6.71793792873124e-05,"d":"6.72E-05"},0.253521756,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000172775","FAM192A",16,57186378,57220028,-1,"protein_coding",80011,"FAM192A",0.944099351189242,-0.529181943,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs1864163;rs9939224:rs118146573:rs3816117:rs9939224:rs11076176:rs12708967:rs12720918:rs1864163",31]
["ENSG00000159579","RSPRY1",16,57220049,57274387,1,"protein_coding",89970,"RSPRY1",0.999778005187676,-0.337763107,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs1864163;rs9939224:rs118146573:rs3816117:rs9939224:rs11076176:rs12708967:rs12720918:rs1864163",31]
["ENSG00000102931","ARL2BP",16,57279010,57287516,1,"protein_coding",23568,"ARL2BP",0.000774155836962192,-0.164113324,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000102962","CCL22",16,57392684,57400102,1,"protein_coding",6367,"CCL22",0.279053454796883,1.694728431,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":3.6e-20,"d":"3.60E-20"},"rs9989419:rs3764261:rs12448528:rs12923459:rs12708967:rs12720918:rs3816117:rs1864163:rs1864163;rs9939224",31]
["ENSG00000140848","CPNE2",16,57126449,57181878,1,"protein_coding",221184,"CPNE2",0.544003069972159,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.3e-19,"d":"1.30E-19"},"rs9989419:rs3764261:rs12448528:rs12923459:rs1864163;rs9939224:rs118146573:rs3816117:rs9939224:rs11076176",31]
["ENSG00000134419","RPS15A",16,18792617,18801705,-1,"protein_coding",6210,"RPS15A",0.833355704516176,-0.376607162,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.3e-11,"d":"7.30E-11"},"rs880071:rs117876551:rs377615530:rs4781684",30]
["ENSG00000260342","RP11-1035H13.3",16,18799385,18812841,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.3e-11,"d":"7.30E-11"},"rs880071:rs117876551:rs377615530:rs4781684",30]
["ENSG00000170540","ARL6IP1",16,18802991,18813000,-1,"protein_coding",23204,"ARL6IP1",0.00667568860937067,-0.374658071,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.3e-11,"d":"7.30E-11"},"rs880071:rs117876551:rs377615530:rs4781684",30]
["ENSG00000224712","NPIPA3",16,14802801,14820195,1,"protein_coding",642778,"NPIPA3","NA",-0.137549156,1,1.867,0,"NA","NA","NA","NA","No","NA",{"v":1.9e-10,"d":"1.90E-10"},"rs188533455;16:14591093_CT_C",30]
["ENSG00000159720","ATP6V0D1",16,67471917,67515140,-1,"protein_coding",9114,"ATP6V0D1",0.988131750847399,-0.042507237,2,6.79,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000159723","AGRP",16,67516474,67517716,-1,"protein_coding",181,"AGRP",0.0903872520171276,-0.228652236,1,6.79,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000141098","GFOD2",16,67708434,67753324,-1,"protein_coding",81577,"GFOD2",0.0605374338437669,-0.955753302,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000141084","RANBP10",16,67757005,67840555,-1,"protein_coding",57610,"RANBP10",0.951824229348564,-2.159196803,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000102904","TSNAXIP1",16,67840668,67866051,1,"protein_coding",55815,"TSNAXIP1",{"v":9.27238409136455e-18,"d":"9.27E-18"},-0.329502309,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000102901","CENPT",16,67862060,67881714,-1,"protein_coding",80152,"CENPT",0.0553623518797919,-0.678945996,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000102898","NUTF2",16,67880635,67906470,1,"protein_coding",10204,"NUTF2",0.885150385053397,-0.697364064,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000038358","EDC4",16,67906926,67918406,1,"protein_coding",23644,"EDC4",0.995195899401119,-0.559324502,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000188038","NRN1L",16,67918708,67922758,1,"protein_coding",123904,"NRN1L",3.86710849157266E-4,-0.414516035,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000159792","PSKH1",16,67927175,67963581,1,"protein_coding",5681,"PSKH1",0.0178742052133664,-1.242927374,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000261884","CTC-479C5.12",16,67963517,67969920,-1,"protein_coding","NA","NA","NA","NA",1,23.4,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000205220","PSMB10",16,67968405,67970990,-1,"protein_coding",5699,"PSMB10",{"v":2.33997900720924e-05,"d":"2.34E-05"},-0.218920453,1,23.4,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000213398","LCAT",16,67973653,67978034,-1,"protein_coding",3931,"LCAT",0.496435716280553,-0.294092703,1,23.4,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000124067","SLC12A4",16,67977377,68003504,-1,"protein_coding",6560,"SLC12A4",{"v":1.82559229552341E-7,"d":"1.83E-07"},-0.363903797,1,23.4,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000167261","DPEP2",16,68021297,68034489,-1,"protein_coding",64174,"DPEP2",{"v":4.01062336318903e-05,"d":"4.01E-05"},-0.461548869,1,5.687,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000167264","DUS2",16,68021649,68113223,1,"protein_coding",54920,"DUS2",2.72032398658379E-4,"NA",1,5.687,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000182810","DDX28",16,68055179,68057770,-1,"protein_coding",55794,"DDX28",0.0348937305744781,-0.695272955,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000072736","NFATC3",16,68118654,68263162,1,"protein_coding",4775,"NFATC3",0.998062457612728,0.527373753,1,0.65,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4e-10,"d":"4.40E-10"},"rs4986970",32]
["ENSG00000141096","DPEP3",16,68009566,68014732,-1,"protein_coding",64180,"DPEP3",{"v":9.13571963954139e-07,"d":"9.14E-07"},-0.50898965,1,5.687,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000103067","ESRP2",16,68263014,68272005,-1,"protein_coding",80004,"ESRP2",0.731424518577173,-1.022746055,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000103066","PLA2G15",16,68279207,68294961,1,"protein_coding",23659,"PLA2G15",0.658429999883026,-0.279350899,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000103061","SLC7A6OS",16,68318406,68344849,-1,"protein_coding",84138,"SLC7A6OS",0.807327025070433,-1.885761498,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000132600","PRMT7",16,68344877,68392466,1,"protein_coding",54496,"PRMT7",{"v":8.30563679212495e-09,"d":"8.31E-09"},-0.873098608,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000103044","HAS3",16,69139467,69152622,1,"protein_coding",3038,"HAS3",0.26938711218293,-0.838005778,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000263203","CHTF8",16,69152757,69154331,-1,"protein_coding",54921,"CHTF8","NA",-0.491897054,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.8e-08,"d":"5.80E-08"},"rs4986970",32]
["ENSG00000135723","FHOD1",16,67263290,67281561,-1,"protein_coding",29109,"FHOD1",{"v":9.46042582987411e-11,"d":"9.46E-11"},0.241354779,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000196155","PLEKHG4",16,67311413,67323402,1,"protein_coding",25894,"PLEKHG4",{"v":1.46441415776125E-9,"d":"1.46E-09"},-1.216852795,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000168676","KCTD19",16,67323331,67360666,-1,"protein_coding",146212,"KCTD19",{"v":3.3389213065673e-08,"d":"3.34E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000159708","LRRC36",16,67360701,67419106,1,"protein_coding",55282,"LRRC36",{"v":3.63105528140864E-10,"d":"3.63E-10"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000159713","TPPP3",16,67423712,67427438,-1,"protein_coding",51673,"TPPP3",0.311517277242007,0.021675506,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000159714","ZDHHC1",16,67428322,67450736,-1,"protein_coding",29800,"ZDHHC1",{"v":5.10929019814853e-06,"d":"5.11E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000176387","HSD11B2",16,67464555,67471456,1,"protein_coding",3291,"HSD11B2",0.244955464937436,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000102977","ACD",16,67691415,67694713,-1,"protein_coding",65057,"ACD",{"v":5.77980161685066E-7,"d":"5.78E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000102981","PARD6A",16,67694849,67696681,1,"protein_coding",50855,"PARD6A",0.854734700838115,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000124074","ENKD1",16,67696848,67701168,-1,"protein_coding",84080,"ENKD1",{"v":2.15383278184853e-05,"d":"2.15E-05"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000159761","C16orf86",16,67700719,67702661,1,"protein_coding",388284,"C16orf86",0.652428951452165,"NA",0,0,1,0.000160554,0.0161727,"GTEx/v8/Pancreas","-","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-07,"d":"2.20E-07"},"rs4986970",32]
["ENSG00000039523","FAM65A",16,67552321,67580691,1,"protein_coding",79567,"FAM65A",0.895578365834564,-0.435666974,1,7.012,0,"NA","NA","NA","NA","Yes","GM12878",{"v":2.1e-06,"d":"2.10E-06"},"rs4986970",32]
["ENSG00000159753","RLTPR",16,67678822,67691472,1,"protein_coding",146206,"RLTPR",0.0223533069911047,"NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-06,"d":"2.10E-06"},"rs4986970",32]
["ENSG00000168286","THAP11",16,67876213,67878097,1,"protein_coding",57215,"THAP11",0.465632985581296,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.1e-06,"d":"2.10E-06"},"rs4986970",32]
["ENSG00000141086","CTRL",16,67961543,67966317,-1,"protein_coding",1506,"CTRL",{"v":7.86917801865378e-06,"d":"7.87E-06"},-0.428819695,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.1e-06,"d":"2.10E-06"},"rs4986970",32]
["ENSG00000102974","CTCF",16,67596310,67673086,1,"protein_coding",10664,"CTCF",0.997924957852537,-0.536092574,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":2.4e-06,"d":"2.40E-06"},"rs4986970",32]
["ENSG00000225190","PLEKHM1",17,43513266,43568115,-1,"protein_coding",9842,"PLEKHM1",0.840543209831517,-0.663068032,140,18.95,2815,{"v":2.76383e-14,"d":"2.76E-14"},{"v":3.72801E-10,"d":"3.73E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250;rs2732699;17:44286218_CA_C;rs112557952;rs9913081;rs549080390;rs71279459;rs55938136;rs35076622;rs2074404;rs7225002;17:44858598_CA_C;rs6503451;rs142925250:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs9303521:rs565716222:rs55938136:rs16940904:rs16940904;rs2074404:rs16940904;rs2732699:rs16940904",34]
["ENSG00000120088","CRHR1",17,43699267,43913194,1,"protein_coding",1394,"CRHR1",0.792134286397601,2.038085631,941,19.39,2909,{"v":1.86977E-23,"d":"1.87E-23"},{"v":2.70499e-18,"d":"2.70E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;17:44286218_CA_C;rs112557952;rs9913081;rs549080390;rs71279459;rs9303521;rs565716222;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;rs35111772;rs2074404;rs142925250;rs7221167;rs6503451;rs2435200;rs7225002;17:44858598_CA_C;rs56755526;rs142925250:rs16940904;rs2074404:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs549080390:rs16940904;rs2732699:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs6503451:rs16940904;rs9913081:rs16940904;rs112557952:rs7225002:rs16940904;rs2732699:rs2732699:rs2696531:rs16940904;rs56755526:rs16940904",34]
["ENSG00000185294","SPPL2C",17,43922256,43924438,1,"protein_coding",162540,"SPPL2C",{"v":2.29524703916312e-05,"d":"2.30E-05"},0.187394842,121,23.5,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952;rs2074404;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs7221167;rs546735951;rs142925250:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs2074404:rs16940904;rs2732699:rs16940904;rs9913081:rs7225002:rs16940904;rs56755526;rs56755526:rs16940904;17:44858598_CA_C;rs549080390;rs549080390:rs16940904;rs112557952:rs71279459:rs16940904;rs112557952:rs9303521:rs565716222:rs55938136:rs16940904;rs2074404:rs2435200:rs16940904;rs9913081:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs35076622:rs6503451:rs16940904;rs112557952:rs369541018:rs16940904;rs2074404:rs112557952:rs16940904;rs2732699:rs2732699:rs2696531:rs71363586:rs16940904",34]
["ENSG00000186868","MAPT",17,43971748,44105700,1,"protein_coding",4137,"MAPT",{"v":4.68264962282433e-05,"d":"4.68E-05"},2.01024275,798,26.8,2912,{"v":1.31245E-17,"d":"1.31E-17"},{"v":4.84413e-68,"d":"4.84E-68"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952;rs2074404;rs6503451;rs549080390;rs2435200;rs7225002;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250;rs55938136;rs7221167;17:44858598_CA_C;rs35076622;rs56755526;rs71279459;rs9303521;rs2074404:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs112557952:rs16940904;rs2732699:rs16940904;rs9913081:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs6503451:rs16940904;rs2074404:rs2435200:rs16940904;rs112557952:17:44286218_CA_C:rs7225002:rs16940904;rs112557952:rs71279459:rs9303521:rs565716222:rs55938136:rs16940904;rs56755526:rs16940904;rs549080390:rs16940904",34]
["ENSG00000256762","STH",17,44076616,44077060,1,"protein_coding",246744,"STH",0.00444466614164462,0.274193181,98,19.15,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404;rs2435200;rs2074404:rs16940904;17:44286218_CA_C:rs16940904;rs549080390;rs112557952:rs16940904;rs112557952:rs16940904:rs16940904;rs2074404:rs7225002:rs16940904;17:44858598_CA_C;rs112557952;rs2074404:rs6503451:rs16940904;rs2732699:rs16940904;rs9913081:rs16940904;rs112557952:17:44286218_CA_C:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs16940904;rs56755526;rs56755526:rs16940904;rs549080390:rs16940904;rs9913081:rs369541018:rs112557952:rs16940904;rs112557952:rs71279459:rs9303521:rs565716222:rs55938136:rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs35076622:rs16940904;rs2732699:rs2732699:rs2696531:rs16940904;rs2074404:17:44858598_CA_C:rs16940904;rs2074404:rs2074404:rs71363586:rs16940904",34]
["ENSG00000120071","KANSL1",17,44107282,44302733,-1,"protein_coding",284058,"KANSL1",0.999733505943003,0.058945245,1075,26.4,2885,{"v":6.14241e-12,"d":"6.14E-12"},{"v":6.72547e-40,"d":"6.73E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:GM12878:Mesenchymal_Stem_Cell",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404;rs112557952;rs7225002;rs549080390;17:44858598_CA_C;rs369541018;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250;rs55938136;rs35076622;rs56755526;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs9913081:rs16940904;rs2732699:rs16940904;rs112557952:rs16940904;rs2074404:rs2435200:rs16940904;rs2074404:rs16940904;rs112557952:17:44286218_CA_C:rs7225002:rs16940904;rs2074404:rs2074404:rs16940904",34]
["ENSG00000176681","LRRC37A",17,44370099,44415160,1,"protein_coding",9884,"LRRC37A",0.890487355591061,"NA",68,15.22,2914,{"v":1.94262E-79,"d":"1.94E-79"},{"v":1.19942E-67,"d":"1.20E-67"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","EP_links_oneway:Promoter_anchored_loops:GM12878:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;rs549080390;rs112557952;17:44858598_CA_C;17:44286218_CA_C;rs71363586;rs9913081;rs7225002;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250;rs71279459;rs55938136;rs35076622;rs2074404;rs7221167;rs6503451;rs2435200;rs56755526;rs2074404:rs16940904;rs9913081:rs16940904;rs112557952:rs16940904:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs2732699:rs7225002:rs16940904;rs112557952:rs369541018:rs16940904;rs2074404:rs112557952:rs16940904;rs2074404:rs2435200:rs16940904;rs56755526:rs16940904;rs549080390:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs6503451",34]
["ENSG00000238083","LRRC37A2",17,44588877,44633016,1,"protein_coding",474170,"LRRC37A2","NA","NA",11,19.03,2771,{"v":8.05734e-120,"d":"8.06E-120"},{"v":1.51829e-103,"d":"1.52E-103"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Mesenchymal_Stem_Cell",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs2732699;rs7225002;rs112557952;17:44858598_CA_C;rs549080390;17:44286218_CA_C;rs9913081;rs71279459;rs9303521;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;rs2074404;rs7221167;rs6503451;rs2435200;rs56755526;rs2074404:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904",34]
["ENSG00000185829","ARL17A",17,44594068,44657088,-1,"protein_coding",51326,"ARL17A","NA",-2.38258287,10,19.03,2765,{"v":3.41734e-19,"d":"3.42E-19"},{"v":6.22486e-21,"d":"6.22E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":1.5E-16,"d":"1.50E-16"},"rs7225002;rs16940904;rs2732699;rs112557952;17:44858598_CA_C;rs549080390;17:44286218_CA_C;rs9913081;rs71279459;rs9303521;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;rs2074404;rs6503451;rs56755526;rs7221167;rs2435200",34]
["ENSG00000073969","NSF",17,44668035,44834830,1,"protein_coding",4905,"NSF",0.713682130183303,-0.566246769,62,17.18,2731,{"v":4.17256e-08,"d":"4.17E-08"},{"v":5.07065e-12,"d":"5.07E-12"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952;rs56755526;rs199470;rs2074404;rs9913081;17:44286218_CA_C;rs9303521;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;rs6503451;rs2435200",34]
["ENSG00000108379","WNT3",17,44839872,44910520,-1,"protein_coding",7473,"WNT3",0.946108101336536,-0.191110949,42,16.08,1926,{"v":4.83642e-27,"d":"4.84E-27"},{"v":1.5414e-26,"d":"1.54E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Mesenchymal_Stem_Cell:hESC",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs56755526;17:44858598_CA_C;rs2732699;rs549080390;rs112557952;rs2074404;rs9913081;17:44286218_CA_C;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs6503451;rs2435200;rs7225002;rs7221167;rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs2074404:rs16940904;rs112557952:rs16940904;rs2732699:rs16940904;rs112557952:rs7225002:rs16940904;rs2074404:rs199470:rs16940904;rs56755526:rs16940904",34]
["ENSG00000179673","RPRML",17,45055523,45056614,-1,"protein_coding",388394,"RPRML",0.421294822682809,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-16,"d":"1.50E-16"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904;rs549080390:rs16940904;rs9913081;17:44286218_CA_C;rs112557952:rs16940904:rs16940904;rs112557952;17:44286218_CA_C:rs7225002:rs16940904;rs9913081:rs16940904;17:44286218_CA_C:rs16940904;rs2732699:rs16940904;rs2732699:rs2732699:rs16940904;rs112557952:rs2696531:rs16940904;rs112557952:rs71279459:rs16940904;rs112557952:rs9303521:rs565716222:rs55938136:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs6503451:rs16940904;rs2074404:rs2435200:rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs35076622:rs16940904;rs2074404:17:44858598_CA_C:rs16940904;rs2074404:rs2074404",34]
["ENSG00000172992","DCAKD",17,43100708,43138473,-1,"protein_coding",79877,"DCAKD",0.0293860851896359,0.848595011,0,0,2032,{"v":1.83107e-06,"d":"1.83E-06"},{"v":2.68979e-32,"d":"2.69E-32"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","No","NA",{"v":3.2e-16,"d":"3.20E-16"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250;rs2732699;17:44286218_CA_C;rs112557952;rs9913081;rs549080390;rs55938136;rs2074404;rs71279459;rs35076622",34]
["ENSG00000004897","CDC27",17,45195069,45266788,-1,"protein_coding",996,"CDC27",0.486673202422918,-0.787143256,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-16,"d":"3.20E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404:rs16940904;rs2074404:rs16940904:rs16940904;rs112557952:rs16940904;rs549080390;17:44286218_CA_C:rs16940904;rs112557952;17:44858598_CA_C;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs56755526;rs56755526:rs16940904",34]
["ENSG00000198336","MYL4",17,45277812,45301045,1,"protein_coding",4635,"MYL4",0.000175624794353708,-0.333740158,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-16,"d":"3.20E-16"},"rs16940904;rs2732699;rs549080390;17:44286218_CA_C;rs112557952:rs16940904;rs2732699:rs16940904;rs9913081;rs2074404:rs16940904:rs16940904;rs112557952;rs2074404:rs16940904;17:44858598_CA_C;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs56755526;rs56755526:rs16940904",34]
["ENSG00000108424","KPNB1",17,45726842,45762871,1,"protein_coding",3837,"KPNB1",0.999994327501246,-0.517927071,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.2e-16,"d":"3.20E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404:rs16940904;rs2074404:rs16940904:rs16940904;rs112557952:rs16940904;rs549080390;17:44286218_CA_C:rs16940904;rs112557952;rs56755526;rs56755526:rs16940904;17:44858598_CA_C;rs549080390:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904",34]
["ENSG00000108433","GOSR2",17,45000483,45105003,1,"protein_coding",9570,"GOSR2",2.8919421780916003E-4,0.147390712,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.5e-16,"d":"3.50E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs549080390;rs2074404:rs16940904;rs2732699:rs16940904;rs112557952;rs2074404:rs7225002:rs16940904;rs9913081:rs16940904;17:44858598_CA_C;rs56755526;rs56755526:rs16940904;rs549080390:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs6503451",34]
["ENSG00000262633","RP11-156P1.2",17,45000499,45124520,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.5e-16,"d":"3.50E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs549080390;rs2074404:rs16940904;rs2732699:rs16940904;rs112557952;rs2074404:rs7225002:rs16940904;rs9913081:rs16940904;17:44858598_CA_C;rs56755526;rs56755526:rs16940904;rs549080390:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs6503451",34]
["ENSG00000159314","ARHGAP27",17,43471275,43511787,-1,"protein_coding",201176,"ARHGAP27",1.25584382196987E-3,-0.761627793,87,18.95,2604,{"v":1.38418e-06,"d":"1.38E-06"},{"v":5.78187E-11,"d":"5.78E-11"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops",{"v":4.1e-16,"d":"4.10E-16"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250;rs2732699;rs112557952;rs9913081;17:44286218_CA_C;rs2074404;rs549080390;17:44858598_CA_C;rs55938136;rs6503451;rs7225002;rs142925250:rs16940904;rs2074404:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs6503451",34]
["ENSG00000184361","SPATA32",17,43331760,43339479,-1,"protein_coding",124783,"SPATA32",{"v":2.95265117999751E-5,"d":"2.95E-05"},-0.414755704,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.4E-16,"d":"4.40E-16"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952;rs2074404:rs16940904;17:44286218_CA_C:rs16940904;rs2074404:rs16940904:rs16940904;rs112557952:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs7221167:rs16940904;rs2074404:rs9913081:rs16940904;rs2732699:rs16940904;rs2074404:rs6503451:rs16940904;rs549080390;17:44858598_CA_C;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904",34]
["ENSG00000259207","ITGB3",17,45331212,45421658,1,"protein_coding",3690,"ITGB3",0.141699544644917,-0.21470934,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4E-16,"d":"4.40E-16"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904;rs549080390:rs16940904;rs9913081;17:44286218_CA_C;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs112557952;rs2074404",34]
["ENSG00000259753","ITGB3",17,45331263,45421658,1,"protein_coding",3690,"ITGB3","NA",-0.21470934,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.4E-16,"d":"4.40E-16"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904;rs549080390:rs16940904;rs9913081;17:44286218_CA_C;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs112557952;rs2074404",34]
["ENSG00000189120","SP6",17,45922279,45933240,-1,"protein_coding",80320,"SP6",0.0229475656346052,-1.129577219,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.4E-16,"d":"4.40E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404:rs16940904;rs549080390;rs112557952:rs16940904;17:44858598_CA_C;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs112557952;rs56755526;rs56755526:rs16940904",34]
["ENSG00000120094","HOXB1",17,46605888,46608359,-1,"protein_coding",3211,"HOXB1",0.115199709546097,-0.795581734,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":4.4E-16,"d":"4.40E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404:rs16940904;rs549080390;rs112557952:rs16940904;17:44858598_CA_C;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs112557952;rs2074404",34]
["ENSG00000173917","HOXB2",17,46618256,46623441,-1,"protein_coding",3212,"HOXB2",1.83830846418713E-3,0.974079452,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":4.4E-16,"d":"4.40E-16"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs2074404:rs16940904;rs549080390;rs112557952:rs16940904;17:44858598_CA_C;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs9913081:rs16940904;rs2074404:rs7225002:rs16940904;rs112557952;rs2074404",34]
["ENSG00000126581","BECN1",17,40962152,40985367,-1,"protein_coding",8678,"BECN1",0.998697775912791,-0.469387595,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.3E-15,"d":"1.30E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs142925250:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",34]
["ENSG00000131467","PSME3",17,40976402,40995774,1,"protein_coding",10197,"PSME3",0.988103823358922,-1.745302754,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.3E-15,"d":"1.30E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs142925250:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",34]
["ENSG00000131480","AOC2",17,40996617,41002724,1,"protein_coding",314,"AOC2",{"v":5.13940212237188e-10,"d":"5.14E-10"},0.041350631,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.3E-15,"d":"1.30E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs142925250:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",34]
["ENSG00000184922","FMNL1",17,43298811,43324687,1,"protein_coding",752,"FMNL1",0.999687036181592,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-15,"d":"1.30E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",34]
["ENSG00000182963","GJC1",17,42875816,42908184,-1,"protein_coding",10052,"GJC1",0.944105282209013,-2.782988352,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.6E-15,"d":"1.60E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs9913081;17:44286218_CA_C:rs16940904;17:44286218_CA_C;rs112557952:rs16940904:rs16940904;rs112557952:rs16940904;rs9913081:rs16940904;rs112557952",34]
["ENSG00000131095","GFAP",17,42982376,42994305,-1,"protein_coding",2670,"GFAP",{"v":2.22936756487388e-05,"d":"2.23E-05"},-0.265503436,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-15,"d":"2.20E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:17:43511281_TGGCTAACACGGTGAAACCCC_T:rs142925250:rs16940904;rs2732699;rs112557952:rs16940904;17:44286218_CA_C;rs2732699:rs16940904;rs9913081;17:44286218_CA_C:rs16940904;rs9913081:rs16940904:rs16940904",34]
["ENSG00000131097","HIGD1B",17,42923721,42927848,1,"protein_coding",51751,"HIGD1B",2.34558353981055E-3,-0.344882798,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3.6e-15,"d":"3.60E-15"},"rs72836561:rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952;rs2074404:rs6503451:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;rs2074404:rs16940904;rs2732699:rs16940904",1.3986111111111112]
["ENSG00000168517","HEXIM2",17,43238067,43247407,1,"protein_coding",124790,"HEXIM2",0.368236513275247,-0.798107113,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.6e-15,"d":"3.60E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs71279459:rs16940904;rs9913081:rs9303521:rs16940904;rs112557952;rs2074404:rs6503451:rs16940904;rs549080390;rs2732699:rs16940904;rs2074404:rs16940904;17:44858598_CA_C;rs2074404",34]
["ENSG00000158955","WNT9B",17,44910567,44964096,1,"protein_coding",7484,"WNT9B",0.0516168107144711,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Mesenchymal_Stem_Cell:hESC",{"v":6.5e-15,"d":"6.50E-15"},"rs16940904:rs16940904;rs2732699;17:44286218_CA_C:rs16940904;17:44286218_CA_C;rs112557952;rs2074404:rs16940904;rs549080390;rs112557952:rs16940904;rs9913081;rs2732699:rs16940904;rs112557952:rs7225002:rs16940904;rs2074404:rs199470:rs16940904;17:44858598_CA_C;rs56755526;rs56755526:rs16940904",34]
["ENSG00000180329","CCDC43",17,42750437,42767147,-1,"protein_coding",124808,"CCDC43",0.000257178261367413,-0.924707928,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver",{"v":7.2e-15,"d":"7.20E-15"},"rs16940904;rs2732699;rs549080390;17:44286218_CA_C;rs112557952:rs16940904;rs2732699:rs16940904;rs9913081;rs2074404:rs16940904:rs16940904;rs112557952;rs2074404:rs16940904;17:44858598_CA_C;rs112557952:rs72836561",1.3986111111111112]
["ENSG00000108883","EFTUD2",17,42927311,42977030,-1,"protein_coding",9343,"EFTUD2",0.999991435314757,0.211209263,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-15,"d":"7.20E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs549080390;17:44286218_CA_C;rs112557952:rs16940904;rs2732699:rs16940904;rs9913081;rs2074404:rs16940904:rs16940904;rs112557952;rs2074404:rs16940904;17:44858598_CA_C",34]
["ENSG00000167131","CCDC103",17,42976510,42982758,1,"protein_coding",388389,"CCDC103",0.00218552270508304,{"v":3.73457e-05,"d":"3.73E-05"},0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-15,"d":"7.20E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs549080390;17:44286218_CA_C;rs112557952:rs16940904;rs2732699:rs16940904;rs9913081;rs2074404:rs16940904:rs16940904;rs112557952;rs2074404:rs16940904;17:44858598_CA_C",34]
["ENSG00000214447","FAM187A",17,42977135,42982758,1,"protein_coding",100528020,"FAM187A","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-15,"d":"7.20E-15"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs16940904;rs2732699;rs549080390;17:44286218_CA_C;rs112557952:rs16940904;rs2732699:rs16940904;rs9913081;rs2074404:rs16940904:rs16940904;rs112557952;rs2074404:rs16940904;17:44858598_CA_C",34]
["ENSG00000228696","ARL17B",17,44352150,44439130,-1,"protein_coding",100506084,"ARL17B","NA",-0.428243465,292,15.22,24,{"v":6.71269e-14,"d":"6.71E-14"},{"v":7.67102e-25,"d":"7.67E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":8.2e-15,"d":"8.20E-15"},"rs16940904;rs2732699;rs549080390;17:44286218_CA_C;rs112557952;rs2074404;17:44858598_CA_C;rs9913081;rs2696531;rs71363586;rs7225002;rs2435200;rs9303521;rs6503451;rs112557952:rs16940904;rs2732699:rs16940904;rs2732699:rs2732699:rs16940904;rs112557952:rs2696531:rs16940904",34]
["ENSG00000181513","ACBD4",17,43209967,43221548,1,"protein_coding",79777,"ACBD4",{"v":1.82643064951694E-5,"d":"1.83E-05"},-0.326407022,0,0,1,{"v":9.3544e-06,"d":"9.35E-06"},{"v":2.53243e-07,"d":"2.53E-07"},"GTEx/v8/Artery_Tibial","+","No","NA",{"v":3.8E-13,"d":"3.80E-13"},"rs16940904;rs35076622",34]
["ENSG00000161647","MPP3",17,41878167,41910538,-1,"protein_coding",4356,"MPP3",{"v":1.99785500256477e-05,"d":"2.00E-05"},"NA",1,3.26,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Lung:Pancreas:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-12,"d":"2.60E-12"},"rs72836561;rs72836561:rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904",1.3986111111111112]
["ENSG00000178852","EFCAB13",17,45400656,45518678,1,"protein_coding",124989,"EFCAB13",{"v":8.2199210022743e-19,"d":"8.22E-19"},-0.190444586,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.6e-12,"d":"2.60E-12"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904",34]
["ENSG00000073861","TBX21",17,45810610,45823485,1,"protein_coding",30009,"TBX21",0.963242650804377,0.083150474,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.6e-12,"d":"2.60E-12"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904",34]
["ENSG00000108439","PNPO",17,46018872,46025654,1,"protein_coding",55163,"PNPO",{"v":3.71896087830709e-05,"d":"3.72E-05"},0.179349996,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":2.6e-12,"d":"2.60E-12"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904",34]
["ENSG00000167183","PRR15L",17,46029333,46035244,-1,"protein_coding",79170,"PRR15L",0.481246950810061,0.303263346,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":2.6e-12,"d":"2.60E-12"},"rs16940904;rs56755526;rs2074404:rs16940904;rs56755526:rs16940904;17:44858598_CA_C;rs2732699;rs549080390;rs112557952:rs16940904",34]
["ENSG00000186834","HEXIM1",17,43224684,43229468,1,"protein_coding",10614,"HEXIM1",0.944400234927573,-1.495314951,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-12,"d":"5.50E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250",34]
["ENSG00000161692","DBF4B",17,42785976,42829632,1,"protein_coding",80174,"DBF4B",{"v":4.43213751313207E-8,"d":"4.43E-08"},-0.507761261,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver",{"v":8e-12,"d":"8.00E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs72836561",1.3986111111111112]
["ENSG00000136448","NMT1",17,43128978,43186384,1,"protein_coding",4836,"NMT1",0.998500520689071,0.032447683,0,0,3,0.000115199,{"v":2.03105e-24,"d":"2.03E-24"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":2.6e-11,"d":"2.60E-11"},"rs9303521;rs71279459;rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs142925250:rs546735951",34]
["ENSG00000108861","DUSP3",17,41843489,41856356,-1,"protein_coding",1845,"DUSP3",0.736744916251957,0.986547234,1,1.893,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000231256","C17orf105",17,41857803,41864980,1,"protein_coding",284067,"C17orf105","NA",-0.266736429,1,3.26,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000161649","CD300LG",17,41924516,41940997,1,"protein_coding",146894,"CD300LG",0.0299351091325868,-0.286688769,1,17.23,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000131096","PYY",17,42030106,42081837,-1,"protein_coding",5697,"PYY",0.0544166347481236,-0.075103266,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000161653","NAGS",17,42081914,42086431,1,"protein_coding",162417,"NAGS",{"v":4.88883525644423e-05,"d":"4.89E-05"},-0.021619152,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000091947","TMEM101",17,42088556,42101314,-1,"protein_coding",84336,"TMEM101",0.161635623953233,-0.333976629,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000161654","LSM12",17,42112003,42144987,-1,"protein_coding",124801,"LSM12",0.931681763448656,-1.278175902,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000141349","G6PC3",17,42148103,42153709,1,"protein_coding",92579,"G6PC3",{"v":1.07483483664146e-05,"d":"1.07E-05"},-0.032947633,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.3e-08,"d":"3.30E-08"},"rs72836561",33]
["ENSG00000089558","KCNH4",17,40308909,40333296,-1,"protein_coding",23415,"KCNH4",0.999978751386027,-0.452983046,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000161610","HCRT",17,40336078,40337470,-1,"protein_coding",3060,"HCRT",0.502440434384708,-0.292071092,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000167925","GHDC",17,40340817,40346531,-1,"protein_coding",84514,"GHDC",{"v":2.1212473947494e-05,"d":"2.12E-05"},-0.790742885,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000131475","VPS25",17,40925454,40931617,1,"protein_coding",84313,"VPS25",0.735077728420435,-0.403388278,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000126562","WNK4",17,40932696,40948954,1,"protein_coding",65266,"WNK4",{"v":1.82873562565171e-13,"d":"1.83E-13"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000183978","COA3",17,40947165,40950722,-1,"protein_coding",28958,"COA3",0.00470837762889433,-0.471662534,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000176563","CNTD1",17,40950810,40963605,1,"protein_coding",124817,"CNTD1",0.0218345110656651,-0.681430812,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000175906","ARL4D",17,41476327,41478505,1,"protein_coding",379,"ARL4D",0.132429775556647,0.197622674,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000067596","DHX8",17,41561233,41621831,1,"protein_coding",1659,"DHX8",0.934509015310341,-0.600362296,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000175832","ETV4",17,41605212,41656988,-1,"protein_coding",2118,"ETV4",2.70290986689264E-3,-0.540761313,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000167941","SOST",17,41831099,41836156,-1,"protein_coding",50964,"SOST",0.379603154764271,-0.581486947,1,1.893,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000108309","RUNDC3A",17,42385781,42396039,1,"protein_coding",10900,"RUNDC3A",0.960334019427912,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7e-07,"d":"1.70E-07"},"rs72836561",33]
["ENSG00000266997","RP11-886H22.1",18,47322163,47363993,-1,"protein_coding","NA","NA","NA","NA",9,5.664,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-22,"d":"2.30E-22"},"rs6417108;rs10639158;rs80175721;rs80204526:rs6417108:rs10639158:rs9964067;rs9947678:rs9964067:rs9947678:rs7505997:rs80175721:rs2000827:rs11662596:rs77960347;rs80204526:rs77960347:rs4121823:rs1105654:rs28666039:rs7229377:rs34802337:rs11663245:rs73959582:rs7235080:rs11662059:rs7230869:rs9304381:rs7229658:rs35739561:rs7228085:rs9947684:rs374401823:rs9304381;rs1540037:rs118043171:rs4939888:rs1540037:rs763363223:rs62101765:rs7505352:rs12456227:rs62101765;rs12456227:rs763363223;rs12456227:rs11875988;rs62101773:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs6507945:rs12965067:rs6507945;rs12965067",35]
["ENSG00000184828","ZBTB7C",18,45553044,45937123,-1,"protein_coding",201501,"ZBTB7C",0.907221460237709,-0.062747095,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-22,"d":"4.40E-22"},"rs35739561:rs7228085:rs9304381:rs9947684:rs374401823:rs9304381;rs1540037:rs118043171:rs7230869:rs4939888:rs1540037:rs763363223:rs62101765:rs7505352:rs12456227:rs62101765;rs12456227:rs763363223;rs12456227:rs11875988;rs62101773:rs80175721:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs2000827:rs6507945:rs12965067:rs6507945;rs12965067:rs6417108:rs7505997:rs9964067;rs9947678:rs9964067:rs9947678:rs10639158:rs1974410",35]
["ENSG00000177576","C18orf32",18,47008028,47013622,-1,"protein_coding",497661,"C18orf32",0.18275268888643,-0.238183839,0,0,1,{"v":4.56943e-05,"d":"4.57E-05"},{"v":7.11808e-09,"d":"7.12E-09"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.4e-22,"d":"4.40E-22"},"rs73959582;rs6417108:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223;rs12456227:rs763363223:rs11875988;rs62101773:rs80175721:rs2000827:rs6507945:rs12965067:rs7505997:rs9947678:rs6507945;rs12965067:rs9964067;rs9947678:rs9964067:rs10639158:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs1974410:rs80204526:rs7228085:rs9947684:rs374401823:rs118043171:rs1540037:rs7505352:rs12456227:rs62101765;rs12456227:rs11662596:rs77960347;rs80204526:rs77960347:rs4121823",35]
["ENSG00000215472","RPL17-C18orf32",18,47008051,47017956,-1,"protein_coding",100526842,"RPL17-C18orf32",0.605942171595584,-0.340213428,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.4e-22,"d":"4.40E-22"},"rs6417108:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223;rs12456227:rs763363223:rs11875988;rs62101773:rs80175721:rs2000827:rs6507945:rs12965067:rs7505997:rs9947678:rs6507945;rs12965067:rs9964067;rs9947678:rs9964067:rs10639158:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs1974410:rs80204526:rs7228085:rs9947684:rs374401823:rs118043171:rs1540037:rs7505352:rs12456227:rs62101765;rs12456227:rs11662596:rs77960347;rs80204526:rs77960347:rs4121823",35]
["ENSG00000265681","RPL17",18,47014851,47018906,-1,"protein_coding",6139,"RPL17",0.494059426420399,0.186983574,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.4e-22,"d":"4.40E-22"},"rs6417108:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223;rs12456227:rs763363223:rs11875988;rs62101773:rs80175721:rs2000827:rs6507945:rs12965067:rs7505997:rs9947678:rs6507945;rs12965067:rs9964067;rs9947678:rs9964067:rs10639158:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs1974410:rs80204526:rs7228085:rs9947684:rs374401823:rs118043171:rs1540037:rs7505352:rs12456227:rs62101765;rs12456227:rs11662596:rs77960347;rs80204526:rs77960347:rs4121823",35]
["ENSG00000167315","ACAA2",18,47309869,47340330,-1,"protein_coding",10449,"ACAA2","NA","NA",8,5.664,15,{"v":3.2722e-05,"d":"3.27E-05"},{"v":6.07479e-14,"d":"6.07E-14"},"GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.4e-22,"d":"4.40E-22"},"rs2000827;rs6417108;rs10639158;rs11662596:rs6417108:rs62101765:rs763363223;rs12456227:rs763363223:rs11875988;rs62101773:rs80175721:rs2000827:rs9947678:rs80204526:rs77960347;rs80204526:rs77960347:rs4121823:rs35739561:rs7228085:rs9304381:rs9947684:rs374401823:rs9304381;rs1540037:rs118043171:rs7230869:rs4939888:rs1540037:rs7505352:rs12456227:rs62101765;rs12456227:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs6507945:rs12965067:rs9964067;rs9947678:rs9964067:rs7505997",35]
["ENSG00000101670","LIPG",18,47087069,47119272,1,"protein_coding",9388,"LIPG",{"v":8.35570265503166e-05,"d":"8.36E-05"},-0.057562727,16,24.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.2e-22,"d":"8.20E-22"},"rs11662596;rs77960347;rs80204526;rs4121823;rs1105654;rs6417108:rs2000827:rs62101765:rs763363223;rs12456227:rs763363223:rs11875988;rs62101773:rs80175721:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs6507945:rs12965067:rs7505997:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs10639158:rs6507945;rs12965067:rs9964067;rs9947678:rs9964067:rs9947678",35]
["ENSG00000172361","CCDC11",18,47753563,47792892,-1,"protein_coding",220136,"CCDC11",{"v":1.5987996365213e-13,"d":"1.60E-13"},-0.596742517,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.2e-22,"d":"8.20E-22"},"rs6417108:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223;rs12456227:rs763363223:rs11875988;rs62101773:rs80175721:rs2000827:rs80204526:rs9947678:rs1974410",35]
["ENSG00000167306","MYO5B",18,47349183,47721463,-1,"protein_coding",4645,"MYO5B",{"v":5.4231747689238e-10,"d":"5.42E-10"},0.470845589,126,18.42,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-16,"d":"4.10E-16"},"rs6417108;rs80175721;rs2000827;rs9947678;rs1974410;rs80204526:rs9947678:rs6417108:rs2000827:rs11662596:rs77960347;rs80204526:rs77960347:rs4121823:rs1974410:rs80175721:rs10639158:rs9964067;rs9947678:rs9964067:rs7505997",35]
["ENSG00000154839","SKA1",18,47901365,47920543,1,"protein_coding",220134,"SKA1",{"v":1.32265949651803E-6,"d":"1.32E-06"},0.423231094,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.1e-13,"d":"2.10E-13"},"rs80204526:rs80175721:rs2000827:rs6417108:rs1974410:rs9947678",35]
["ENSG00000141627","DYM",18,46570039,46987717,-1,"protein_coding",54808,"DYM",{"v":5.18111501130597e-09,"d":"5.18E-09"},-0.135200517,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":9.1e-12,"d":"9.10E-12"},"rs6417108:rs10639158:rs80175721:rs2000827:rs9947678:rs9964067;rs9947678:rs9964067:rs7505997",35]
["ENSG00000267228","IER3IP1",18,44661027,44702652,-1,"protein_coding",51124,"IER3IP1","NA",-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.8e-11,"d":"3.80E-11"},"rs9947678:rs6417108:rs2000827",35]
["ENSG00000134049","IER3IP1",18,44681413,44702745,-1,"protein_coding",51124,"IER3IP1",0.0184346889412637,-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.8e-11,"d":"3.80E-11"},"rs9947678:rs6417108:rs2000827",35]
["ENSG00000215474","SKOR2",18,44746293,44775554,-1,"protein_coding",652991,"SKOR2",0.611171343025554,-0.166850887,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.8e-11,"d":"3.80E-11"},"rs9947678:rs6417108:rs2000827:rs1974410",35]
["ENSG00000206181","TCEB3B",18,44558943,44561988,-1,"protein_coding",51224,"TCEB3B",{"v":1.80367559188731E-8,"d":"1.80E-08"},-0.015254462,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1e-09,"d":"1.00E-09"},"rs2000827:rs6417108:rs1974410",35]
["ENSG00000154832","CXXC1",18,47808713,47814674,-1,"protein_coding",30827,"CXXC1",0.99786210530366,-0.476982834,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.4e-07,"d":"1.40E-07"},"rs6417108",35]
["ENSG00000187664","HAPLN4",19,19366450,19373605,-1,"protein_coding",404037,"HAPLN4",0.0326847848265823,0.204997517,19,26.2,183,{"v":6.79586E-20,"d":"6.80E-20"},{"v":6.88492e-19,"d":"6.88E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","EP_correlation_cell_type_oneway",{"v":5.9e-55,"d":"5.90E-55"},"rs11882123;rs58542926;rs2285626;19:19510831_AT_A;rs182611493;rs17216693;rs8100204",37]
["ENSG00000213996","TM6SF2",19,19375173,19384200,-1,"protein_coding",53345,"TM6SF2",{"v":1.93541173325793e-05,"d":"1.94E-05"},"NA",35,26.2,251,{"v":1.17275e-20,"d":"1.17E-20"},{"v":8.90299e-16,"d":"8.90E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.9e-55,"d":"5.90E-55"},"rs58542926;rs11882123;rs2285626;19:19510831_AT_A;rs182611493;rs35431065;rs8100204;rs17216693;19:19756073_AGCC_A;rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs182611493:rs3761077:rs58542926;rs3761077:rs144787624",37]
["ENSG00000105705","SUGP1",19,19386827,19431653,-1,"protein_coding",57794,"SUGP1",0.9996355600486,"NA",84,26.2,4,{"v":3.15025e-05,"d":"3.15E-05"},{"v":5.87709e-05,"d":"5.88E-05"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":5.9e-55,"d":"5.90E-55"},"rs11882123;rs58542926;rs182611493;rs2285626;19:19510831_AT_A;rs35431065;rs8100204;rs73001020;rs17216693;19:19438110_GTATT_G;rs11882123:rs2285626:rs2285626",37]
["ENSG00000105726","ATP13A1",19,19756007,19774502,-1,"protein_coding",57130,"ATP13A1",0.994473888962369,"NA",2,8.763,94,{"v":3.16696e-16,"d":"3.17E-16"},{"v":9.80314e-12,"d":"9.80E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.9e-55,"d":"5.90E-55"},"rs58542926;19:19756073_AGCC_A;rs143729015;rs61061000;rs3761077;rs35431065;rs8100204;rs73001020;rs17216693;rs2285626;19:19510831_AT_A;rs11882123;19:19756073_AGCC_A:19:19756073_AGCC_A:rs11882123:rs58542926:rs2285626:rs144787624:rs117414940",37]
["ENSG00000064607","SUGP2",19,19101697,19144832,-1,"protein_coding",10147,"SUGP2",0.999366871236062,0.523631183,5,6.776,31,{"v":6.38872E-7,"d":"6.39E-07"},{"v":4.0018e-05,"d":"4.00E-05"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7e-54,"d":"1.70E-54"},"rs143729015;rs73001020;rs11085253;rs61061000;rs143729015:rs11085253:rs61061000:rs11882123:rs58542926:rs2285626:rs144787624:rs182611493:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs61061000;rs28672836:rs28672836",37]
["ENSG00000105676","ARMC6",19,19144384,19170563,1,"protein_coding",93436,"ARMC6",{"v":7.24407726209859e-07,"d":"7.24E-07"},"NA",1,0.21,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7e-54,"d":"1.70E-54"},"rs143729015;rs143729015:rs11085253:rs61061000:rs11882123:rs58542926:rs2285626:rs144787624:rs182611493:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs61061000;rs28672836:rs28672836",37]
["ENSG00000130287","NCAN",19,19322782,19363042,1,"protein_coding",1463,"NCAN",0.154546738217425,-1.280770396,8,23,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":1.7e-54,"d":"1.70E-54"},"rs182611493;rs3761077;rs58542926;rs11882123;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs182611493:19:19510831_AT_A:rs144787624",37]
["ENSG00000250067","YJEFN3",19,19627036,19648390,1,"protein_coding",374887,"YJEFN3",{"v":2.63542608769062e-06,"d":"2.64E-06"},"NA",23,19.09,209,{"v":2.19112E-15,"d":"2.19E-15"},{"v":3.19891e-16,"d":"3.20E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex",{"v":1.7e-54,"d":"1.70E-54"},"rs11882123;rs144787624;rs2285626;rs17216693;19:19510831_AT_A;rs58542926;rs73001020;19:19756073_AGCC_A;rs143729015;rs12985293;rs11882123:rs2285626",37]
["ENSG00000197124","ZNF682",19,20107867,20150315,-1,"protein_coding",91120,"ZNF682",{"v":3.67329437341058e-09,"d":"3.67E-09"},1.212036464,0,0,1,{"v":9.3218e-05,"d":"9.32E-05"},0.00051934,"GTEx/v8/Artery_Tibial","-","No","NA",{"v":1.7e-54,"d":"1.70E-54"},"rs58542926",37]
["ENSG00000064545","TMEM161A",19,19229978,19249322,-1,"protein_coding",54929,"TMEM161A",{"v":2.04658505555468e-06,"d":"2.05E-06"},-0.270254201,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-46,"d":"1.40E-46"},"rs143729015:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs2285626:rs182611493:rs58542926:rs144787624",37]
["ENSG00000129933","MAU2",19,19431490,19469563,1,"protein_coding",23383,"MAU2",0.999717755369344,0.014423646,86,15.92,20,{"v":2.45442e-05,"d":"2.45E-05"},0.0377692,"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":1.4e-46,"d":"1.40E-46"},"rs2285626;19:19510831_AT_A;rs11882123;rs58542926;19:19438110_GTATT_G;rs73001020;rs182611493;rs144787624;rs11882123:rs2285626:rs2285626",37]
["ENSG00000167491","GATAD2A",19,19496635,19619740,1,"protein_coding",54815,"GATAD2A",0.995362828250654,-0.496926306,122,19.09,29,{"v":9.95736e-06,"d":"9.96E-06"},0.0106309,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":1.4e-46,"d":"1.40E-46"},"rs11882123;rs2285626;19:19510831_AT_A;rs58542926;19:19756073_AGCC_A;rs17216693;19:19503203_GT_G;rs73001020;rs77653002;rs144787624;rs143729015:rs11882123:rs58542926:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs2285626:rs144787624",37]
["ENSG00000268193","AC002985.3",19,19017822,19045206,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.5e-45,"d":"1.50E-45"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs144787624",37]
["ENSG00000064489","MEF2BNB-MEF2B",19,19256376,19302967,-1,"protein_coding",4207,"MEF2BNB-MEF2B",0.247287511423171,-0.149548186,108,12.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.5e-45,"d":"1.50E-45"},"rs61061000;rs28672836;rs11085253;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",37]
["ENSG00000213999","MEF2B",19,19256377,19303400,-1,"protein_coding",100271849,"MEF2B",0.590447262915793,"NA",108,12.47,45,{"v":3.23375e-08,"d":"3.23E-08"},0.000173774,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.5e-45,"d":"1.50E-45"},"rs61061000;rs28672836;rs11085253;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",37]
["ENSG00000254901","MEF2BNB",19,19287712,19303400,-1,"protein_coding",729991,"MEF2BNB","NA",0.579437175,60,12.34,58,{"v":7.7977e-15,"d":"7.80E-15"},{"v":3.62201e-19,"d":"3.62E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.5e-45,"d":"1.50E-45"},"rs61061000;rs11085253;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",37]
["ENSG00000064490","RFXANK",19,19303008,19312678,1,"protein_coding",8625,"RFXANK",0.000671163624692492,0.789997306,20,9.408,3,0.000100607,0.0177117,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.5e-45,"d":"1.50E-45"},"rs11085253;rs61061000;rs182611493;rs73001020;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",37]
["ENSG00000160161","CILP2",19,19649057,19657468,1,"protein_coding",148113,"CILP2",0.000278936233123941,-0.132917182,16,11.63,154,{"v":2.34002e-13,"d":"2.34E-13"},{"v":7.52088e-21,"d":"7.52E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.5e-45,"d":"1.50E-45"},"rs11882123;rs2285626;rs17216693;19:19510831_AT_A;rs58542926;rs12985293;rs182611493:rs3761077:rs58542926;rs3761077:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs144787624:rs2285626;19:19510831_AT_A:rs12985293:rs58542926;19:19756073_AGCC_A",37]
["ENSG00000181896","ZNF101",19,19779605,19794318,1,"protein_coding",94039,"ZNF101",{"v":5.76614320550034e-07,"d":"5.77E-07"},-0.001974248,3,11.91,38,{"v":2.56484E-5,"d":"2.56E-05"},0.0223002,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":1.5e-45,"d":"1.50E-45"},"19:19756073_AGCC_A;rs61061000;rs58542926;rs3761077;rs11882123:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs58542926:rs2285626:rs144787624:rs117414940",37]
["ENSG00000081665","ZNF506",19,19896648,19932560,-1,"protein_coding",440515,"ZNF506",{"v":1.99612668014446E-8,"d":"2.00E-08"},-0.298399589,0,0,15,{"v":4.66246e-05,"d":"4.66E-05"},{"v":1.69948E-26,"d":"1.70E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Left_Ventricle","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-45,"d":"1.50E-45"},"rs58542926;rs17216693;19:19756073_AGCC_A;rs73001020;rs2285626;rs12985293;rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A",37]
["ENSG00000105642","KCNN1",19,18062102,18110889,1,"protein_coding",3780,"KCNN1",0.931699633359926,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.1E-45,"d":"2.10E-45"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626",37]
["ENSG00000184162","NR2C2AP",19,19312225,19314233,-1,"protein_coding",126382,"NR2C2AP",0.527167735331819,-0.417894074,1,0.149,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.1E-45,"d":"2.10E-45"},"rs182611493;rs11085253:rs61061000:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs58542926:rs2285626",37]
["ENSG00000105708","ZNF14",19,19821280,19843906,-1,"protein_coding",7561,"ZNF14",{"v":5.71582699182454e-16,"d":"5.72E-16"},-0.140934352,1,0.401,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Fetal_Cortex",{"v":2.1E-45,"d":"2.10E-45"},"rs117414940;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:19:19756073_AGCC_A",37]
["ENSG00000223802","CERS1",19,18979361,19007536,-1,"protein_coding",10715,"CERS1",0.0454570437212016,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-44,"d":"3.20E-44"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs182611493:rs2285626;rs17216693;19:19510831_AT_A",37]
["ENSG00000130283","GDF1",19,18979361,19006905,-1,"protein_coding",2657,"GDF1",0.544923744446604,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-44,"d":"3.20E-44"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs182611493:rs2285626;rs17216693;19:19510831_AT_A",37]
["ENSG00000105717","PBX4",19,19672522,19729725,-1,"protein_coding",80714,"PBX4",0.006772126187306,-0.679896521,27,8.295,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.6E-42,"d":"2.60E-42"},"rs12985293;rs58542926;rs17216693;19:19756073_AGCC_A",37]
["ENSG00000184635","ZNF93",19,20011722,20046384,1,"protein_coding",81931,"ZNF93",0.00169182185612759,0.174728697,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6E-42,"d":"2.60E-42"},"rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A",37]
["ENSG00000268461","AC007204.1",19,20047769,20048639,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6E-42,"d":"2.60E-42"},"rs11882123:rs2285626:rs2285626;rs17216693;19:19510831_AT_A:rs58542926;rs17216693:rs12985293:rs17216693:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs117414940",37]
["ENSG00000213988","ZNF90",19,20188803,20237885,1,"protein_coding",7643,"ZNF90",{"v":1.22410273221888e-07,"d":"1.22E-07"},1.219480619,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.6E-42,"d":"2.60E-42"},"rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A",37]
["ENSG00000256229","ZNF486",19,20278037,20311299,1,"protein_coding",90649,"ZNF486",{"v":1.88053183954875e-08,"d":"1.88E-08"},1.705728223,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.6E-42,"d":"2.60E-42"},"rs12985293:rs58542926;19:19756073_AGCC_A:rs117414940",37]
["ENSG00000188171","ZNF626",19,20802867,20844402,-1,"protein_coding",199777,"ZNF626",{"v":2.3449662444854E-7,"d":"2.34E-07"},10.77102824,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A",37]
["ENSG00000118620","ZNF430",19,21203426,21242856,1,"protein_coding",80264,"ZNF430",0.000180790697407956,0.502386975,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs12985293:rs58542926;19:19756073_AGCC_A:rs117414940",37]
["ENSG00000160352","ZNF714",19,21264965,21308073,1,"protein_coding",148206,"ZNF714",{"v":7.33708061274363e-06,"d":"7.34E-06"},0.728801136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs12985293:rs58542926;19:19756073_AGCC_A:rs117414940",37]
["ENSG00000182141","ZNF708",19,21473962,21512227,-1,"protein_coding",7562,"ZNF708",{"v":4.17756094613551e-09,"d":"4.18E-09"},1.095220078,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs12985293:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A",37]
["ENSG00000172687","ZNF738",19,21541732,21562104,1,"protein_coding",148203,"ZNF738",0.106373218916856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs12985293:rs58542926;19:19756073_AGCC_A:rs117414940",37]
["ENSG00000196268","ZNF493",19,21579921,21610375,1,"protein_coding",284443,"ZNF493",{"v":3.18649368326509e-08,"d":"3.19E-08"},2.729194243,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A",37]
["ENSG00000269237","CTD-2561J22.3",19,21587961,21674068,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A",37]
["ENSG00000197013","ZNF429",19,21679484,21739072,1,"protein_coding",353088,"ZNF429",{"v":9.7121420957407e-14,"d":"9.71E-14"},-0.124310103,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6E-42,"d":"2.60E-42"},"rs117414940:rs12985293:rs58542926;19:19756073_AGCC_A",37]
["ENSG00000064547","LPAR2",19,19734477,19739739,-1,"protein_coding",9170,"LPAR2",0.337269896843433,-0.426142953,3,7.254,154,{"v":3.80631e-12,"d":"3.81E-12"},{"v":1.22846e-27,"d":"1.23E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":7.6e-42,"d":"7.60E-42"},"rs58542926;19:19756073_AGCC_A;rs11882123",37]
["ENSG00000089639","GMIP",19,19740285,19754476,-1,"protein_coding",51291,"GMIP",{"v":7.29298933296636e-05,"d":"7.29E-05"},-0.277164354,2,8.763,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":9.1e-37,"d":"9.10E-37"},"rs58542926;19:19756073_AGCC_A;rs11882123",37]
["ENSG00000178093","TSSK6",19,19623227,19626838,-1,"protein_coding",83983,"TSSK6",0.587550746537451,-1.568432771,20,19.09,15,{"v":2.83493E-5,"d":"2.83E-05"},{"v":3.58402e-05,"d":"3.58E-05"},"GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex",{"v":3.8e-35,"d":"3.80E-35"},"rs11882123;rs2285626;rs144787624;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",37]
["ENSG00000186010","NDUFA13",19,19626545,19644285,1,"protein_coding",51079,"NDUFA13",1.21026586319051E-4,-0.285091511,23,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.8e-35,"d":"3.80E-35"},"rs11882123;rs144787624;rs2285626;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",37]
["ENSG00000258674","CTC-260F20.3",19,19627036,19646885,1,"protein_coding","NA","NA","NA","NA",21,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.8e-35,"d":"3.80E-35"},"rs11882123;rs144787624;rs2285626;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",37]
["ENSG00000256294","ZNF225",19,44616334,44637027,1,"protein_coding",7768,"ZNF225",{"v":3.36669333303033e-08,"d":"3.37E-08"},0.547354183,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8E-25,"d":"1.80E-25"},"rs111784051:rs41290120:rs7412",38]
["ENSG00000073008","PVR",19,45147098,45166850,1,"protein_coding",5817,"PVR",{"v":5.51101308161619e-07,"d":"5.51E-07"},-0.732916848,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-25,"d":"1.80E-25"},"rs190921611:rs12721109:rs57465754:rs111784051:rs7412",38]
["ENSG00000130204","TOMM40",19,45393826,45406946,1,"protein_coding",10452,"TOMM40",0.963682323765023,"NA",11,25.1,2,{"v":4.48241e-05,"d":"4.48E-05"},4.8747E-3,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-25,"d":"1.80E-25"},"rs111784051;rs7412;rs7412:rs190921611:rs57465754:rs34827707:rs12721109",38]
["ENSG00000130203","APOE",19,45409011,45412650,1,"protein_coding",348,"APOE",0.0345335830833016,-0.237445173,7,25.1,1,{"v":4.00707e-05,"d":"4.01E-05"},0.0461303,"GTEx/v8/Pancreas","+","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs111784051;rs7412;rs190921611;rs190921611:rs12721109:rs57465754",38]
["ENSG00000130208","APOC1",19,45417504,45422606,1,"protein_coding",341,"APOC1",0.0507382728810443,-0.105569458,7,25.1,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs7412;rs190921611:rs34827707:rs12721109:rs57465754",38]
["ENSG00000224916","APOC4-APOC2",19,45445495,45452822,1,"protein_coding",100533990,"APOC4-APOC2","NA","NA",24,17.4,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs190921611;rs12721109;rs111784051:rs7412:rs34827707:rs41290120",38]
["ENSG00000267467","APOC4",19,45445495,45452820,1,"protein_coding",346,"APOC4",0.000150692347626422,0.337274035,24,17.4,44,{"v":4.4607e-14,"d":"4.46E-14"},{"v":3.56734e-09,"d":"3.57E-09"},"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs190921611;rs12721109;rs57465754;rs111784051:rs7412:rs34827707:rs41290120",38]
["ENSG00000234906","APOC2",19,45449243,45452822,1,"protein_coding",344,"APOC2",0.0227961322934307,0.388732718,24,17.4,50,{"v":5.34361e-12,"d":"5.34E-12"},{"v":1.21381e-15,"d":"1.21E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs190921611;rs12721109;rs111784051:rs7412:rs34827707:rs41290120",38]
["ENSG00000267114","CTB-129P6.11",19,45453301,45457264,-1,"protein_coding","NA","NA","NA","NA",19,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs190921611;rs12721109;rs57465754;rs111784051:rs7412:rs34827707:rs190921611:rs57465754:rs41290120",38]
["ENSG00000104853","CLPTM1",19,45457842,45496599,1,"protein_coding",1209,"CLPTM1",0.98048307691788,"NA",47,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs190921611;rs57465754;rs111784051:rs7412:rs34827707:rs190921611:rs57465754:rs41290120",38]
["ENSG00000104859","CLASRP",19,45542298,45574214,1,"protein_coding",11129,"CLASRP",0.964966482147783,-0.085202503,1,1.868,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-25,"d":"1.80E-25"},"rs34827707;rs111784051:rs7412:rs190921611:rs57465754:rs12721109",38]
["ENSG00000007255","TRAPPC6A",19,45666186,45681495,-1,"protein_coding",79090,"TRAPPC6A",0.000705277787371492,-0.133842318,1,0.065,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8E-25,"d":"1.80E-25"},"rs34827707;rs7412:rs190921611:rs57465754:rs34827707",38]
["ENSG00000189114","BLOC1S3",19,45682003,45685059,1,"protein_coding",388552,"BLOC1S3",0.0184297702580611,-0.115773028,1,0.065,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8E-25,"d":"1.80E-25"},"rs34827707;rs7412:rs190921611:rs57465754:rs34827707",38]
["ENSG00000267545","AC005779.2",19,45683080,45705702,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8E-25,"d":"1.80E-25"},"rs7412:rs190921611:rs57465754:rs34827707",38]
["ENSG00000181035","SLC25A42",19,19174808,19223697,1,"protein_coding",284439,"SLC25A42",0.208308450498004,-0.880389707,1,0.194,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1E-14,"d":"1.00E-14"},"rs143729015;rs143729015:rs61061000;rs28672836:rs28672836:rs11085253:rs61061000",37]
["ENSG00000141979","CTD-3222D19.2",19,16589878,16739015,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015",37]
["ENSG00000105085","MED26",19,16685718,16739873,-1,"protein_coding",9441,"MED26",0.948549941884627,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015",37]
["ENSG00000105656","ELL",19,18553473,18632937,-1,"protein_coding",8178,"ELL",0.940941238331597,-0.635599911,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015",37]
["ENSG00000221983","UBA52",19,18682540,18688360,1,"protein_coding",7311,"UBA52",0.4468000697986,1.709183735,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015:rs73001020;rs143729015",37]
["ENSG00000006016","CRLF1",19,18683030,18718551,-1,"protein_coding",9244,"CRLF1",0.026855594173361,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015:rs73001020;rs143729015",37]
["ENSG00000006015","C19orf60",19,18699495,18703146,1,"protein_coding",55049,"C19orf60",0.249879077699029,0.549025716,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015:rs73001020;rs143729015",37]
["ENSG00000105696","TMEM59L",19,18718240,18731849,1,"protein_coding",25789,"TMEM59L",0.0151007864967939,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.2e-13,"d":"4.20E-13"},"rs143729015:rs73001020;rs143729015",37]
["ENSG00000130202","PVRL2",19,45349432,45392485,1,"protein_coding",5819,"PVRL2",0.531937435077773,-0.314456223,8,15.03,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.2e-12,"d":"1.20E-12"},"rs111784051;rs41290120;rs111784051:rs41290120",38]
["ENSG00000254858","MPV17L2",19,18303992,18307758,1,"protein_coding",84769,"MPV17L2",{"v":1.67296107198305e-07,"d":"1.67E-07"},0.464900432,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6e-12,"d":"6.00E-12"},"rs143729015",37]
["ENSG00000105701","FKBP8",19,18642561,18654887,-1,"protein_coding",23770,"FKBP8",0.9787380986207,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6e-12,"d":"6.00E-12"},"rs143729015",37]
["ENSG00000105662","CRTC1",19,18794487,18893004,1,"protein_coding",23373,"CRTC1",0.980548236291021,-2.587605964,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6e-12,"d":"6.00E-12"},"rs143729015",37]
["ENSG00000142453","CARM1",19,10982189,11033453,1,"protein_coding",10498,"CARM1",0.999357708272541,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-11,"d":"1.30E-11"},"rs151113958",36]
["ENSG00000130733","YIPF2",19,11033444,11039357,-1,"protein_coding",78992,"YIPF2",1.09917458451604E-3,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.3E-11,"d":"1.30E-11"},"rs151113958",36]
["ENSG00000142444","C19orf52",19,11039409,11044211,1,"protein_coding",90580,"C19orf52",0.00198991933916563,-0.096033732,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.3E-11,"d":"1.30E-11"},"rs151113958",36]
["ENSG00000130164","LDLR",19,11200038,11244492,1,"protein_coding",3949,"LDLR",{"v":2.59266073718312e-16,"d":"2.59E-16"},0.415051182,45,13.85,0,"NA","NA","NA","NA","No","NA",{"v":1.3E-11,"d":"1.30E-11"},"rs151113958",36]
["ENSG00000173928","SWSAP1",19,11485361,11487627,1,"protein_coding",126074,"SWSAP1",0.000134670403718243,-0.594213988,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.3E-11,"d":"1.30E-11"},"rs151113958",36]
["ENSG00000102575","ACP5",19,11685475,11689823,-1,"protein_coding",54,"ACP5",0.123568347500175,-0.16646465,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.3E-11,"d":"1.30E-11"},"rs151113958",36]
["ENSG00000131116","ZNF428",19,44111371,44124026,-1,"protein_coding",126299,"ZNF428",0.720275479182866,-0.650154352,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754",38]
["ENSG00000105767","CADM4",19,44126520,44143991,-1,"protein_coding",199731,"CADM4",0.979491544538579,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754",38]
["ENSG00000216588","IGSF23",19,45116940,45140081,1,"protein_coding",147710,"IGSF23","NA",0.573724812,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754",38]
["ENSG00000186567","CEACAM19",19,45165545,45187631,1,"protein_coding",56971,"CEACAM19",{"v":5.7765093789489e-07,"d":"5.78E-07"},0.414157593,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754",38]
["ENSG00000213892","CEACAM16",19,45202421,45213986,1,"protein_coding",388551,"CEACAM16",0.0295802581415047,-0.586640098,0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs41290120:rs190921611:rs12721109:rs57465754",38]
["ENSG00000130201","EXOC3L2",19,45715879,45737469,-1,"protein_coding",90332,"EXOC3L2",0.925564031557031,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754:rs34827707",38]
["ENSG00000104879","CKM",19,45809672,45826235,-1,"protein_coding",1158,"CKM",0.00505058616928749,0.03849229,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754:rs34827707",38]
["ENSG00000104892","KLC3",19,45836692,45854778,1,"protein_coding",147700,"KLC3",{"v":3.15849310261577e-06,"d":"3.16E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754:rs34827707",38]
["ENSG00000268341","L47234.1",19,45842445,45842639,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754",38]
["ENSG00000104884","ERCC2",19,45853095,45874176,-1,"protein_coding",2068,"ERCC2",{"v":3.14163491830693e-13,"d":"3.14E-13"},-0.123245341,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6E-11,"d":"1.60E-11"},"rs190921611:rs12721109:rs57465754",38]
["ENSG00000105518","TMEM205",19,11453452,11457194,-1,"protein_coding",374882,"TMEM205",0.394574027164483,-0.471673866,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":6E-11,"d":"6.00E-11"},"rs151113958",36]
["ENSG00000104856","RELB",19,45504688,45541452,1,"protein_coding",5971,"RELB",0.973562746007932,"NA",14,16.15,0,"NA","NA","NA","NA","No","NA",{"v":1.6e-10,"d":"1.60E-10"},"rs190921611;rs57465754;rs34827707",38]
["ENSG00000125746","EML2",19,46110252,46148887,-1,"protein_coding",24139,"EML2",{"v":7.57699496433696e-10,"d":"7.58E-10"},0.190257397,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.6e-10,"d":"1.60E-10"},"rs190921611:rs57465754:rs34827707",38]
["ENSG00000267757","C19orf83",19,46144752,46146098,1,"protein_coding",100287177,"C19orf83","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.6e-10,"d":"1.60E-10"},"rs190921611:rs57465754:rs34827707",38]
["ENSG00000130511","SSBP4",19,18529674,18545372,1,"protein_coding",170463,"SSBP4",0.96165888216155,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.4E-10,"d":"5.40E-10"},"rs143729015",37]
["ENSG00000105650","PDE4C",19,18318771,18366229,-1,"protein_coding",5143,"PDE4C",{"v":4.88574724786651e-05,"d":"4.89E-05"},0.288881628,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8e-10,"d":"8.00E-10"},"rs143729015",37]
["ENSG00000187244","BCAM",19,45312328,45324673,1,"protein_coding",4059,"BCAM",0.0368511835228543,"NA",1,9.825,0,"NA","NA","NA","NA","No","NA",{"v":1.8E-9,"d":"1.80E-09"},"rs41290120",38]
["ENSG00000256771","ZNF253",19,19976695,20005483,1,"protein_coding",56242,"ZNF253",{"v":1.33295852799606e-06,"d":"1.33E-06"},0.279040894,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.5e-09,"d":"5.50E-09"},"rs117414940",37]
["ENSG00000237440","ZNF737",19,20718631,20748615,-1,"protein_coding",100129842,"ZNF737",{"v":1.10579189398794E-7,"d":"1.11E-07"},1.355633218,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.5e-09,"d":"5.50E-09"},"rs117414940",37]
["ENSG00000160229","ZNF66",19,20959110,20991922,1,"protein_coding",7617,"ZNF66",{"v":5.45295491875167e-17,"d":"5.45E-17"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.5e-09,"d":"5.50E-09"},"rs117414940",37]
["ENSG00000197020","ZNF100",19,21905568,21950430,-1,"protein_coding",163227,"ZNF100",{"v":7.10189425692909e-13,"d":"7.10E-13"},1.454526972,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.5e-09,"d":"5.50E-09"},"rs117414940",37]
["ENSG00000160321","ZNF208",19,22115760,22193751,-1,"protein_coding",7757,"ZNF208",{"v":5.00161251193924e-20,"d":"5.00E-20"},-0.087489856,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.5e-09,"d":"5.50E-09"},"rs117414940",37]
["ENSG00000196109","ZNF676",19,22361893,22379753,-1,"protein_coding",163223,"ZNF676",{"v":1.6869849435551e-06,"d":"1.69E-06"},0.244027382,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":5.5e-09,"d":"5.50E-09"},"rs117414940",37]
["ENSG00000167378","IRGQ",19,44088521,44100287,-1,"protein_coding",126298,"IRGQ",1.19722791198288E-3,-1.836457701,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707:rs190921611",38]
["ENSG00000124444","ZNF576",19,44100544,44105309,1,"protein_coding",79177,"ZNF576",0.007545747912442,-1.085568404,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707:rs190921611",38]
["ENSG00000226763","SRRM5",19,44100769,44118649,1,"protein_coding",100170229,"SRRM5",{"v":7.19141934794887e-06,"d":"7.19E-06"},-0.661940966,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707:rs190921611",38]
["ENSG00000159882","ZNF230",19,44507100,44518078,1,"protein_coding",7773,"ZNF230",0.00834108463646319,1.880496895,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000142273","CBLC",19,45281126,45303891,1,"protein_coding",23624,"CBLC",1.82989540193376E-4,-0.348046092,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000170684","ZNF296",19,45574758,45579846,-1,"protein_coding",162979,"ZNF296",0.97328866403764,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000104866","PPP1R37",19,45594654,45651335,1,"protein_coding",284352,"PPP1R37","NA",0.143949947,1,7.261,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs12721109;rs34827707",38]
["ENSG00000125740","FOSB",19,45971253,45978437,1,"protein_coding",2354,"FOSB",0.852916176747718,-1.205388313,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000125743","SNRPD2",19,46190712,46195827,-1,"protein_coding",6633,"SNRPD2",0.747515256284436,-0.475801412,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000011478","QPCTL",19,46195741,46207247,1,"protein_coding",54814,"QPCTL",0.000261539862441849,-0.638078993,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000177051","FBXO46",19,46213887,46234162,-1,"protein_coding",23403,"FBXO46",0.876437042044124,0.090543664,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000237452","AC074212.3",19,46236509,46267792,1,"protein_coding",388553,"BHMG1",0.376320934323438,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000125755","SYMPK",19,46318668,46366548,-1,"protein_coding",8189,"SYMPK",0.997278492187137,-0.384639791,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000170608","FOXA3",19,46367247,46377055,1,"protein_coding",3171,"FOXA3",0.395510308295114,-0.452953673,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000230510","PPP5D1",19,46984053,47104457,-1,"protein_coding",100506012,"PPP5D1",0.0393450229909042,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000268423","AC011551.3",19,47050313,47104118,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000160014","CALM3",19,47104331,47114050,1,"protein_coding",808,"CALM3",0.580172431977243,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000090372","STRN4",19,47222764,47250251,-1,"protein_coding",29888,"STRN4",0.999575131657329,-0.5987751,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.6e-08,"d":"1.60E-08"},"rs34827707",38]
["ENSG00000130158","DOCK6",19,11309971,11373157,-1,"protein_coding",57572,"DOCK6",{"v":2.83089712599404e-19,"d":"2.83E-19"},"NA",11,23.1,1,1.59023E-4,0.0160196,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs2278426",36]
["ENSG00000130173","C19orf80",19,11348178,11352619,1,"protein_coding",55908,"C19orf80",{"v":2.61107498638975e-06,"d":"2.61E-06"},-0.019228124,5,23.1,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs2278426",36]
["ENSG00000266958","AC006126.3",19,45690646,45720191,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.5e-07,"d":"1.50E-07"},"rs190921611",38]
["ENSG00000129353","SLC44A2",19,10713133,10755235,1,"protein_coding",57153,"SLC44A2",0.0414645881648824,-0.378860929,0,0,2,{"v":2.77111E-5,"d":"2.77E-05"},0.000289454,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":1.4E-5,"d":"1.40E-05"},"rs151113958",36]
["ENSG00000196757","ZNF700",19,12035883,12061588,1,"protein_coding",90592,"ZNF700",{"v":4.39166088843519E-11,"d":"4.39E-11"},0.364854347,0,0,3,{"v":4.47579e-05,"d":"4.48E-05"},3.03929E-3,"GTEx/v8/Artery_Tibial","-","No","NA",{"v":3.4E-5,"d":"3.40E-05"},"rs2278426",36]
["ENSG00000007047","MARK4",19,45582546,45808541,1,"protein_coding",57787,"MARK4",0.999932135718548,"NA",2,7.261,0,"NA","NA","NA","NA","No","NA",0.00061,"rs12721109;rs34827707",38]
["ENSG00000179846","NKPD1",19,45653008,45663408,-1,"protein_coding",284353,"NKPD1",{"v":1.88741865526868e-09,"d":"1.89E-09"},"NA",2,7.261,0,"NA","NA","NA","NA","No","NA",0.00061,"rs12721109;rs34827707",38]

{"sheet":"ST4B","index":5,"n_rows":851,"n_cols":23,"rows_kept":851}
["ensg","symbol","chr","start","end","strand","type","entrezID","HUGO","pLI","ncRVIS","posMapSNPs","posMapMaxCADD","eqtlMapSNPs","eqtlMapminP","eqtlMapminQ","eqtlMapts","eqtlDirection","ciMap","ciMapts","minGwasP","IndSigSNPs","GenomicLocus"]
["ENSG00000162585","C1orf86",1,2115903,2144159,-1,"protein_coding",199990,"C1orf86",0.785170903024389,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000269554","AL590822.2",1,2121237,2123179,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000203301","AL590822.1",1,2143360,2145620,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000157933","SKI",1,2160134,2241558,1,"protein_coding",6497,"SKI",0.981402099833324,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000116151","MORN1",1,2252692,2323146,-1,"protein_coding",79906,"MORN1",{"v":7.87931445985798e-07,"d":"7.88E-07"},"NA",7,5.012,0,"NA","NA","NA","NA","No","NA",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000269753","AL589739.1",1,2258581,2259042,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs6693447",1]
["ENSG00000157916","RER1",1,2323267,2336883,1,"protein_coding",11079,"RER1",0.969239732851388,-0.558230626,10,5.341,0,"NA","NA","NA","NA","No","NA",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000157911","PEX10",1,2336236,2345236,-1,"protein_coding",5192,"PEX10",0.010463632475946,-0.228251586,9,5.341,1,{"v":6.97114e-05,"d":"6.97E-05"},{"v":1.74245e-13,"d":"1.74E-13"},"GTEx/v8/Adipose_Subcutaneous","-","No","NA",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000149527","PLCH2",1,2357419,2436969,1,"protein_coding",9651,"PLCH2",{"v":1.70518647543863e-08,"d":"1.71E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000157881","PANK4",1,2439972,2458039,-1,"protein_coding",55229,"PANK4",0.945333401831958,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000157873","TNFRSF14",1,2487078,2496821,1,"protein_coding",8764,"TNFRSF14",0.819999054408814,-0.131268421,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000215912","TTC34",1,2567415,2718286,-1,"protein_coding",100287898,"TTC34","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000142611","PRDM16",1,2985732,3355185,1,"protein_coding",63976,"PRDM16",0.999843194473124,1.535659419,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs6693447",1]
["ENSG00000130762","ARHGEF16",1,3370990,3397677,1,"protein_coding",27237,"ARHGEF16",{"v":9.36505312388017e-08,"d":"9.37E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000162591","MEGF6",1,3406484,3528059,-1,"protein_coding",1953,"MEGF6",{"v":4.42421031130217e-15,"d":"4.42E-15"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000158109","TPRG1L",1,3541566,3546691,1,"protein_coding",127262,"TPRG1L",0.00284528475212618,0.358352134,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000116213","WRAP73",1,3547331,3569325,-1,"protein_coding",49856,"WRAP73",0.0269219902261615,-0.367755392,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000078900","TP73",1,3569084,3652765,1,"protein_coding",7161,"TP73",0.975977778366269,1.361617859,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8e-08,"d":"1.80E-08"},"rs6693447",1]
["ENSG00000116209","TMEM59",1,54497347,54519177,-1,"protein_coding",9528,"TMEM59",{"v":2.23025067852854E-7,"d":"2.23E-07"},0.206649282,0,0,1,{"v":2.03947E-5,"d":"2.04E-05"},1.96452E-3,"GTEx/v8/Artery_Aorta","+","No","NA",{"v":2.6e-09,"d":"2.60E-09"},"rs11591147",2]
["ENSG00000169174","PCSK9",1,55505221,55530525,1,"protein_coding",255738,"PCSK9",{"v":1.02507611210468E-10,"d":"1.03E-10"},0.264270736,1,15.41,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-09,"d":"2.60E-09"},"rs11591147",2]
["ENSG00000134709","HOOK1",1,60280458,60342050,1,"protein_coding",51361,"HOOK1",{"v":4.15670073195207e-05,"d":"4.16E-05"},-0.06279745,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":3e-63,"d":"3.00E-63"},"rs1167998;rs371562288:rs1183851;rs1168100:rs912540;rs536629310:rs1167998;rs11208009;rs371562288:rs11207998:rs76272805:rs746077597:rs1167998:rs116665700:rs373836691:rs1183851",3]
["ENSG00000134716","CYP2J2",1,60358980,60392462,-1,"protein_coding",1573,"CYP2J2",{"v":4.51201698997771e-12,"d":"4.51E-12"},0.320327764,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1E-10,"d":"1.00E-10"},"rs6587970:rs35837000:rs76272805:rs6587973",3]
["ENSG00000162599","NFIA",1,61330931,61928465,1,"protein_coding",4774,"NFIA",0.999555166212873,-0.180372327,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.3e-12,"d":"9.30E-12"},"rs6587973:rs371337535:rs72929768:rs2780874:rs116665700",3]
["ENSG00000132854","KANK4",1,62702651,62785085,-1,"protein_coding",163782,"KANK4",{"v":5.3984986278488e-08,"d":"5.40E-08"},-0.458433659,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.3e-12,"d":"9.30E-12"},"rs6587970:rs35837000:rs76272805:rs6587973:rs371337535:rs72929768",3]
["ENSG00000162607","USP1",1,62901968,62917475,1,"protein_coding",7398,"USP1",0.993180568281562,-1.542076225,54,18.26,8,{"v":1.97043E-7,"d":"1.97E-07"},4.32786E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-63,"d":"3.00E-63"},"rs11207998;rs1167998;rs11208009;rs371562288;rs1183851;rs746077597;rs912540;rs536629310;rs1168100;rs2149116;rs11208014:rs6688417;rs7512480;rs12564421:rs1167998;rs371562288:rs1167998:rs912540;rs536629310:rs11207998:rs1167998;rs371562288:rs116665700:rs746077597:rs373836691:rs1183851:rs1183851;rs1168100:rs76272805:rs1167998;rs11208009:rs374131620:rs1183851;rs2149116:1:63185902_CT_C:rs11208009:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:1:63268136_TA_T:rs6688417:1:63045366_GA_G:rs2780874",3]
["ENSG00000116641","DOCK7",1,62920399,63153969,-1,"protein_coding",85440,"DOCK7",0.771361085896655,"NA",315,18.64,542,{"v":1.09201E-20,"d":"1.09E-20"},{"v":9.93875E-16,"d":"9.94E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3e-63,"d":"3.00E-63"},"rs1167998;rs11208009;rs371562288;rs746077597;rs912540;rs536629310;rs11207998;rs116665700;rs373836691;rs1183851;rs55853774;rs17381383;rs370129568;rs1168100;rs76272805;1:63045366_GA_G;1:63130453_TA_T;1:63131385_CAA_C;1:63134595_CA_C;1:63149883_TA_T;rs72929768;rs2149116;rs11208014;rs11809792;rs12129277;rs6688417;rs12564421;rs7512480;1:63190449_GTTTTTTTT_G:rs912540:rs11208009:rs2149116:rs1167998;rs371562288:rs1167998:rs912540;rs536629310:rs11207998:rs1167998;rs371562288:rs116665700:rs746077597:rs373836691:rs1183851:rs76272805:1:63045366_GA_G:rs1183851",3]
["ENSG00000132855","ANGPTL3",1,63063158,63071830,1,"protein_coding",27329,"ANGPTL3",{"v":2.12015609401708e-07,"d":"2.12E-07"},-0.803837249,16,12.12,15,{"v":1.13102e-05,"d":"1.13E-05"},0.0421505,"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-63,"d":"3.00E-63"},"rs11207998;rs1167998;rs371562288;rs11208009;rs371562288:rs1167998:rs912540;rs536629310:rs11207998:rs1167998;rs371562288:rs116665700:rs746077597:rs373836691:rs1183851:rs1183851;rs1168100:rs76272805:rs1167998;rs11208009:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs11208009:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs370129568:rs371562288:rs536629310:rs17381383:rs1168100:rs55853774:1:63130453_TA_T:1:63131385_CAA_C:1:63134595_CA_C:1:63149883_TA_T:rs72929768:rs11208014:rs6688417;rs12564421:rs11809792:rs12129277:rs6688417:rs6688417;rs7512480:rs6688417;rs7512480;rs12564421:1:63268136_TA_T:rs6688417;rs11208014;rs12564421:rs12564421:rs7512480:rs2780874",3]
["ENSG00000269624","AL138847.1",1,63073437,63075249,1,"protein_coding","NA","NA","NA","NA",11,12.12,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-63,"d":"3.00E-63"},"rs1167998;rs371562288;rs1183851;rs1168100;rs11208009;rs371562288:rs1167998:rs912540;rs536629310:rs11207998:rs1167998;rs371562288:rs116665700:rs746077597:rs373836691:rs1183851:rs1183851;rs1168100:rs76272805:rs1167998;rs11208009:rs374131620:rs1183851;rs2149116:1:63185902_CT_C:rs11208009:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs370129568:rs371562288:rs536629310:rs17381383:rs1168100:rs55853774:1:63130453_TA_T:1:63131385_CAA_C:1:63134595_CA_C:1:63149883_TA_T:rs72929768:rs11208014:rs6688417;rs12564421:rs11809792:rs12129277:rs6688417:rs6688417;rs7512480:rs6688417;rs7512480;rs12564421:1:63268136_TA_T:rs6688417;rs11208014;rs12564421:rs12564421:rs7512480:rs2780874",3]
["ENSG00000125703","ATG4C",1,63249806,63331184,1,"protein_coding",84938,"ATG4C",{"v":3.32761781234443e-09,"d":"3.33E-09"},-0.809376853,165,17.7,150,{"v":6.89586e-06,"d":"6.90E-06"},0.00836476,"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3e-63,"d":"3.00E-63"},"rs11208014;rs6688417;rs7512480;rs12564421;1:63268136_TA_T;rs11809792;rs12129277;rs116665700;rs1167998:rs1167998;rs11208009;rs371562288:rs1183851:rs1167998;rs371562288:rs746077597:rs912540;rs536629310:rs11207998:rs116665700:rs373836691:rs72929768:rs1167998;rs11208009:rs370129568:rs371562288:rs536629310:rs17381383:rs1168100:rs76272805:1:63045366_GA_G:rs1183851;rs1168100:rs2780874:rs55853774:rs912540",3]
["ENSG00000187140","FOXD3",1,63788730,63790797,1,"protein_coding",27022,"FOXD3","NA",-0.433105976,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.4E-8,"d":"3.40E-08"},"rs2780874:rs116665700",3]
["ENSG00000088035","ALG6",1,63833261,63904233,1,"protein_coding",29929,"ALG6",0.0553676261725129,-0.307102505,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.4e-18,"d":"4.40E-18"},"rs2780874:rs116665700:rs6688417;rs7512480;rs12564421:rs11809792:rs11208014:rs6688417:rs12564421:rs7512480",3]
["ENSG00000142856","ITGB3BP",1,63906441,64059392,-1,"protein_coding",23421,"ITGB3BP",{"v":1.47054021720334E-5,"d":"1.47E-05"},-0.391812829,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":3.4E-8,"d":"3.40E-08"},"rs2780874:rs116665700",3]
["ENSG00000203965","EFCAB7",1,63989043,64038364,1,"protein_coding",84455,"EFCAB7",{"v":1.67071925383672e-12,"d":"1.67E-12"},-0.503488032,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3e-63,"d":"3.00E-63"},"rs2780874:rs116665700:rs6587973:rs371337535:rs72929768:rs11207998:rs1167998:rs1167998;rs11208009;rs371562288:rs1183851:rs1167998;rs371562288:rs746077597:rs1167998;rs11208009:rs912540;rs536629310:rs373836691:rs6688417;rs7512480;rs12564421:rs11809792:rs11208014:rs12129277:rs6688417;rs12564421:rs6688417;rs11208014;rs12564421:rs6688417:rs12564421:rs7512480:rs76272805:1:63045366_GA_G:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs11208009:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:1:63268136_TA_T:rs55853774:rs17381383:rs1183851",3]
["ENSG00000116652","DLEU2L",1,64014588,64015405,1,"protein_coding",79469,"DLEU2L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-63,"d":"3.00E-63"},"rs1167998;rs11208009;rs371562288:rs1167998:rs912540;rs536629310:rs11207998:rs1167998;rs371562288:rs116665700:rs746077597:rs373836691:rs1183851:rs6688417;rs7512480;rs12564421:rs11809792:rs11208014:rs6688417:rs12564421:rs7512480:rs2780874:rs12129277:rs6688417;rs12564421:rs6688417;rs11208014;rs12564421:1:63268136_TA_T:rs370129568:rs371562288:rs536629310:rs17381383:rs1168100:rs1183851;rs1168100:rs76272805:rs1167998;rs11208009:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs11208009:1:63190449_GTTTTTTTT_G:rs912540:rs2149116",3]
["ENSG00000079739","PGM1",1,64058947,64125916,1,"protein_coding",5236,"PGM1",{"v":9.96139807231456e-06,"d":"9.96E-06"},1.203178507,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":3.4E-8,"d":"3.40E-08"},"rs2780874:rs116665700",3]
["ENSG00000158966","CACHD1",1,64936428,65158741,1,"protein_coding",57685,"CACHD1",0.838036969203847,0.056390161,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.4E-8,"d":"3.40E-08"},"rs2780874:rs116665700",3]
["ENSG00000162437","RAVER2",1,65210778,65298915,1,"protein_coding",55225,"RAVER2",{"v":1.85996394365043E-6,"d":"1.86E-06"},-0.746777186,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-63,"d":"3.20E-63"},"rs1167998;rs371562288:rs11207998:rs116665700:rs370129568:rs1167998:rs371562288:rs536629310:rs17381383:rs746077597:rs1168100:rs912540;rs536629310:rs6587973:rs371337535:rs72929768:rs6688417;rs7512480;rs12564421:rs11809792:rs11208014:rs6688417:rs12564421:rs7512480:rs2780874:rs76272805:1:63045366_GA_G:rs1167998;rs11208009:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs11208009:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs12129277:rs6688417;rs12564421:rs6688417;rs11208014;rs12564421",3]
["ENSG00000116675","DNAJC6",1,65713902,65881552,1,"protein_coding",9829,"DNAJC6",0.99918835079312,-0.584518275,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs2780874:rs116665700",3]
["ENSG00000121957","GPSM2",1,109417972,109477167,1,"protein_coding",29899,"GPSM2",{"v":2.9412972070079e-10,"d":"2.94E-10"},0.141117521,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway",{"v":2.2e-07,"d":"2.20E-07"},"rs6657811",4]
["ENSG00000085433","WDR47",1,109512836,109584850,-1,"protein_coding",22911,"WDR47",0.90566161819711,-0.351230971,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway",{"v":2.2e-07,"d":"2.20E-07"},"rs6657811",4]
["ENSG00000179902","C1orf194",1,109648573,109656479,-1,"protein_coding",127003,"C1orf194",{"v":2.50029511352176e-07,"d":"2.50E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway",{"v":2.2e-07,"d":"2.20E-07"},"rs6657811",4]
["ENSG00000116299","KIAA1324",1,109656301,109749401,1,"protein_coding",57535,"KIAA1324",{"v":2.14864520738644E-8,"d":"2.15E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway",{"v":2.2e-07,"d":"2.20E-07"},"rs6657811",4]
["ENSG00000031698","SARS",1,109756540,109780791,1,"protein_coding",6301,"SARS",0.999150650957633,-0.332037527,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.4E-14,"d":"1.40E-14"},"rs629301:rs629301;rs4970834",4]
["ENSG00000143126","CELSR2",1,109792641,109818372,1,"protein_coding",1952,"CELSR2",0.999999199832348,0.807304437,17,18.47,16,{"v":9.42742e-34,"d":"9.43E-34"},{"v":2.20583e-27,"d":"2.21E-27"},"GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Spleen",{"v":4.5e-15,"d":"4.50E-15"},"rs6657811;rs4970834;rs629301;rs629301:rs629301;rs4970834:rs6657811:rs4970834",4]
["ENSG00000134222","PSRC1",1,109822178,109825808,-1,"protein_coding",84722,"PSRC1",{"v":1.74717788563073e-06,"d":"1.75E-06"},-0.208880013,13,18.47,16,{"v":1.0541E-37,"d":"1.05E-37"},{"v":1.834e-30,"d":"1.83E-30"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":4.5e-15,"d":"4.50E-15"},"rs4970834;rs629301;rs6657811",4]
["ENSG00000221986","MYBPHL",1,109834987,109849663,-1,"protein_coding",343263,"MYBPHL",0.00461844098878081,0.281706372,0,0,0,"NA","NA","NA","NA","Yes","EP_links_oneway",{"v":2.2e-07,"d":"2.20E-07"},"rs6657811",4]
["ENSG00000134243","SORT1",1,109852192,109940573,-1,"protein_coding",6272,"SORT1",0.999926560036891,-1.346190944,0,0,16,{"v":3.08634e-54,"d":"3.09E-54"},{"v":3.21918e-45,"d":"3.22E-45"},"GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.5e-15,"d":"4.50E-15"},"rs6657811;rs4970834;rs629301;rs6657811:rs629301:rs629301;rs4970834:rs4970834",4]
["ENSG00000143028","SYPL2",1,110009180,110024759,1,"protein_coding",284612,"SYPL2",0.0167710987562036,0.437866135,0,0,14,{"v":5.67264E-10,"d":"5.67E-10"},{"v":1.41445e-54,"d":"1.41E-54"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.5e-15,"d":"4.50E-15"},"rs6657811;rs4970834;rs629301;rs6657811:rs4970834:rs629301;rs4970834:rs629301",4]
["ENSG00000162650","ATXN7L2",1,110026101,110035426,1,"protein_coding",127002,"ATXN7L2",0.718954812432385,"NA",0,0,10,{"v":5.83014e-07,"d":"5.83E-07"},{"v":6.65426e-17,"d":"6.65E-17"},"GTEx/v8/Liver","-","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.5e-15,"d":"4.50E-15"},"rs629301;rs4970834;rs6657811:rs4970834:rs629301;rs4970834:rs629301",4]
["ENSG00000174151","CYB561D1",1,110036674,110045554,1,"protein_coding",284613,"CYB561D1",0.0158304191038284,-0.395994268,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.5e-15,"d":"4.50E-15"},"rs6657811:rs4970834:rs629301;rs4970834:rs629301",4]
["ENSG00000181754","AMIGO1",1,110046797,110052360,-1,"protein_coding",57463,"AMIGO1",0.888492588974354,-0.212526248,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":4e-10,"d":"4.00E-10"},"rs6657811",4]
["ENSG00000156097","GPR61",1,110082494,110091028,1,"protein_coding",83873,"GPR61",0.801488898268086,-0.586870154,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4e-10,"d":"4.00E-10"},"rs6657811",4]
["ENSG00000240857","RDH14",2,18735989,18741946,-1,"protein_coding",57665,"RDH14",0.232943493348579,-0.65948759,0,0,0,"NA","NA","NA","NA","Yes","IMR90:hESC",{"v":4.7E-17,"d":"4.70E-17"},"rs10184054:rs62122481:rs952275:rs533617",5]
["ENSG00000068697","LAPTM4A",2,20232411,20251789,-1,"protein_coding",9741,"LAPTM4A",0.503802410255576,0.09428312,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-12,"d":"8.40E-12"},"rs4075673:rs10184054;rs4296389:rs533617",5]
["ENSG00000055917","PUM2",2,20448452,20551995,-1,"protein_coding",23369,"PUM2",0.999922863782349,-1.032631297,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":4.7E-17,"d":"4.70E-17"},"rs10184054:rs62122481:rs952275:rs533617",5]
["ENSG00000143878","RHOB",2,20646835,20649200,1,"protein_coding",388,"RHOB",0.245030976539202,-0.338452643,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":4.7E-17,"d":"4.70E-17"},"rs10184054:rs62122481:rs952275:rs533617",5]
["ENSG00000118960","HS1BP3",2,20760208,20850849,-1,"protein_coding",64342,"HS1BP3",0.000353324886507251,2.114325929,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-18,"d":"4.00E-18"},"rs10184054:rs62122481:rs952275:rs533617:rs10184054;rs4296389:rs4075673:rs4296389:rs1800481:rs668948;rs1800481:rs60403635:rs668948:rs34468875:rs668948;rs34601365;rs432483:rs12618122:rs668948;rs432483:rs34601365:rs368220458:rs4635554",5]
["ENSG00000143869","GDF7",2,20866424,20873418,1,"protein_coding",151449,"GDF7",0.778067351749562,0.171953881,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-18,"d":"4.00E-18"},"rs10184054:rs62122481:rs952275:rs533617:rs10184054;rs4296389:rs4075673:rs4296389:rs1800481:rs668948;rs1800481:rs60403635:rs668948:rs34468875:rs668948;rs34601365;rs432483:rs12618122:rs668948;rs432483:rs34601365:rs368220458:rs4635554",5]
["ENSG00000118961","C2orf43",2,20883788,21022882,-1,"protein_coding",60526,"C2orf43",0.00064748477489379,-0.605069014,0,0,27,{"v":8.16419e-06,"d":"8.16E-06"},{"v":1.70489e-23,"d":"1.70E-23"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-18,"d":"4.00E-18"},"rs952275;rs34468875;rs10184054:rs62122481:rs952275:rs533617:rs10184054;rs4296389:rs4075673:rs4296389:rs668948;rs1800481:rs668948:rs60403635:rs34468875:rs668948;rs34601365;rs432483:rs1800481:rs12618122:rs668948;rs432483:rs34601365:rs368220458:rs4635554",5]
["ENSG00000084674","APOB",2,21224301,21266945,-1,"protein_coding",338,"APOB",{"v":5.49085163436995e-16,"d":"5.49E-16"},-0.34689194,30,24.9,320,{"v":3.56067e-26,"d":"3.56E-26"},{"v":1.88901e-24,"d":"1.89E-24"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-18,"d":"4.00E-18"},"rs62122481;rs952275;rs10184054;rs533617;rs1800481;rs668948;rs60403635;rs4296389;rs4075673;rs34468875;rs4635554;rs34601365;rs432483;rs12618122;rs1848922;rs10184054:rs62122481:rs952275:rs533617:rs668948;rs1800481:rs668948:rs60403635:rs34468875:rs668948;rs432483:rs12618122:rs668948;rs432483:rs34601365:rs368220458:rs4635554",5]
["ENSG00000218819","TDRD15",2,21346789,21366144,1,"protein_coding",100129278,"TDRD15","NA","NA",25,10.66,13,{"v":1.23348E-7,"d":"1.23E-07"},{"v":4.5811e-10,"d":"4.58E-10"},"GTEx/v8/Liver","-","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-18,"d":"4.00E-18"},"rs668948;rs34601365;rs432483;rs34468875;rs12618122;rs1800481:rs668948:rs60403635:rs34468875:rs668948;rs432483:rs34601365:rs12618122:rs368220458:rs4635554:rs10184054:rs62122481:rs952275:rs533617:rs1800481",5]
["ENSG00000119771","KLHL29",2,23608088,23931481,1,"protein_coding",114818,"KLHL29","NA",-0.399831988,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4e-18,"d":"4.00E-18"},"rs10184054:rs62122481:rs952275:rs533617:rs1800481:rs668948;rs1800481:rs60403635:rs668948:rs668948;rs34601365;rs432483:rs34468875:rs34601365:rs12618122:rs368220458:rs4635554:rs432483:rs432483;rs1848922:rs1848922",5]
["ENSG00000224361","AC011239.1",2,23729913,23747214,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.7E-17,"d":"4.70E-17"},"rs10184054:rs62122481:rs952275:rs533617",5]
["ENSG00000143970","ASXL2",2,25956622,26101385,-1,"protein_coding",55252,"ASXL2",0.992738818422806,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2E-22,"d":"1.20E-22"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104",6]
["ENSG00000268412","AC013449.1",2,26251074,26251481,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.2E-22,"d":"1.20E-22"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104",6]
["ENSG00000084733","RAB10",2,26256976,26360323,1,"protein_coding",10890,"RAB10",0.944404791408518,-0.583904709,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.2E-22,"d":"1.20E-22"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104",6]
["ENSG00000173567","GPR113",2,26531041,26569685,-1,"protein_coding",165082,"GPR113",{"v":1.48528745876047E-10,"d":"1.49E-10"},0.291622367,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2E-22,"d":"1.20E-22"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104",6]
["ENSG00000157856","DRC1",2,26624784,26679579,1,"protein_coding",92749,"DRC1",{"v":1.30453003302834e-10,"d":"1.30E-10"},0.353225525,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":6.3e-32,"d":"6.30E-32"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs74340299:rs780110;rs556013357:rs780110:rs35686293:rs76476582:rs74630263",6]
["ENSG00000213699","SLC35F6",2,26987152,27004099,1,"protein_coding",54978,"SLC35F6",0.0161307579092324,-0.353050684,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.3e-32,"d":"6.30E-32"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs74340299:rs780110;rs556013357:rs780110",6]
["ENSG00000115163","CENPA",2,26987157,27023935,1,"protein_coding",1058,"CENPA",0.139975206060218,-0.80838147,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.3e-32,"d":"6.30E-32"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs74340299:rs780110;rs556013357:rs780110",6]
["ENSG00000084764","MAPRE3",2,27193480,27250064,1,"protein_coding",22924,"MAPRE3",0.799864407370243,-0.767319281,0,0,6,0.000127027,{"v":6.08981e-07,"d":"6.09E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Adult_Cortex:Fetal_Cortex:Spleen:GM12878:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":9e-77,"d":"9.00E-77"},"rs4665386;rs1870325;rs74630263:rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs77535061;rs76476582:rs34796799:rs74340299:rs1395;rs12053390:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs4665377;rs12053390:rs149996558:rs80051818:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs780110;rs556013357:rs780110:rs142398019:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs35686293",6]
["ENSG00000119777","TMEM214",2,27255778,27264563,1,"protein_coding",54867,"TMEM214",0.00116735534958103,-0.517227915,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":9e-77,"d":"9.00E-77"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs80051818:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs1395;rs12053390:rs4665377;rs1395:rs74630263:2:27498734_ACCCCCG_A:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs780110;rs556013357:rs780110:rs142398019",6]
["ENSG00000084693","AGBL5",2,27265232,27293490,1,"protein_coding",60509,"AGBL5",0.0206948513459665,-0.378650928,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":9e-77,"d":"9.00E-77"},"rs1395;rs12053390:rs4665377;rs1395:rs4665377;rs12053390:rs74630263:rs12053390:2:27498734_ACCCCCG_A:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs8179219:rs80051818:rs556013357:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs780110;rs556013357:rs780110:rs142398019:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326",6]
["ENSG00000228474","OST4",2,27293340,27294641,-1,"protein_coding",100128731,"OST4","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs12053390:rs77535061;rs76476582:rs34796799:rs8179219:rs4665377;rs1395;rs12053390:rs74340299:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs80051818:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs780110;rs556013357:rs780110:rs74630263:rs35686293:rs1395;rs12053390:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs4665377;rs12053390:rs149996558:rs2580757:rs1395:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs142398019",6]
["ENSG00000138080","EMILIN1",2,27301435,27309271,1,"protein_coding",11117,"EMILIN1",0.00521656081419512,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs12053390:rs4665377;rs1395;rs12053390:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs74630263:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs80051818:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs780110;rs556013357:rs780110:rs780110;2:27498734_ACCCCCG_A:rs4665377;rs1395:rs1395;rs12053390:2:27498734_ACCCCCG_A:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs35686293:rs2580757:rs1395:rs556013357:rs142398019",6]
["ENSG00000138030","KHK",2,27309615,27323640,1,"protein_coding",3795,"KHK",{"v":5.36079485314004e-05,"d":"5.36E-05"},"NA",2,4.743,129,{"v":7.23788e-13,"d":"7.24E-13"},{"v":2.2178e-62,"d":"2.22E-62"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs35686293;rs76476582;rs74630263;rs2580757;rs1395;rs4665377;rs12053390;rs34796799;rs3817588;rs11682583;rs58199976;rs202049562;2:27832736_CA_C;rs4665386;rs113160276;rs1870325;rs13013484;rs6714106;rs12053390:rs4665377;rs12053390:rs74630263:rs12053390:rs1395:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs77535061;rs76476582:rs34796799:rs8179219:rs74340299:rs4665377;rs12053390:rs149996558:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs80051818:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs780110;rs556013357:rs780110:rs780110;2:27498734_ACCCCCG_A:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs35686293:rs2580757:rs556013357:rs142398019",6]
["ENSG00000138028","CGREF1",2,27321757,27341995,-1,"protein_coding",10669,"CGREF1",{"v":5.50290788195318E-8,"d":"5.50E-08"},0.491986309,2,4.743,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs35686293;rs76476582;rs4665377;rs1395;rs12053390:rs1395:rs1395;rs12053390:rs4665377;rs1395:rs12053390:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs35686293:rs76476582:rs74630263:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs80051818:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs780110;rs556013357:rs780110:rs780110;2:27498734_ACCCCCG_A:rs3817588:rs74630263;rs11682583:2:27498734_ACCCCCG_A:rs556013357:rs142398019:rs2580757",6]
["ENSG00000143994","ABHD1",2,27346682,27353680,1,"protein_coding",84696,"ABHD1",{"v":1.06027288753589e-21,"d":"1.06E-21"},-0.251069432,1,1.885,4,{"v":3.3649e-05,"d":"3.36E-05"},0.00344467,"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs74630263;rs2580757;rs4665377;rs1395;rs12053390:rs1395:rs1395;rs12053390:rs4665377;rs1395:rs12053390:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs35686293:rs76476582:rs74630263:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs80051818:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs780110;rs556013357:rs780110:rs780110;2:27498734_ACCCCCG_A:rs3817588:rs74630263;rs11682583:2:27498734_ACCCCCG_A:rs556013357:rs142398019:rs2580757",6]
["ENSG00000138073","PREB",2,27353624,27357543,-1,"protein_coding",10113,"PREB",0.0018983627682706,-0.154458724,1,1.885,1,0.000203631,0.000891037,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs74630263;rs2580757;rs8179219:rs80051818:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs4665377;rs1395:rs1395;rs12053390:rs4665377;rs1395;rs12053390:rs74630263:rs12053390:rs77535061;rs76476582:rs34796799:rs74340299:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs780110;rs556013357:rs780110:rs35686293:2:27498734_ACCCCCG_A:rs4665377;rs12053390:rs149996558:rs556013357:rs142398019:rs2580757:rs1395",6]
["ENSG00000186143","C2orf53",2,27359723,27362278,-1,"protein_coding",339779,"C2orf53",{"v":1.54927478958821e-09,"d":"1.55E-09"},0.62491408,1,1.885,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.2E-22,"d":"1.20E-22"},"rs74630263;rs1395;rs12053390:rs4665377;rs12053390:rs74630263:rs35686293:rs12053390:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs76476582:rs1395:rs4665377;rs1395:2:27498734_ACCCCCG_A",6]
["ENSG00000163792","TCF23",2,27371872,27376378,1,"protein_coding",150921,"TCF23",0.000503312310069814,-0.683069484,12,15.48,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.2E-22,"d":"1.20E-22"},"rs2580757;rs4665377;rs1395;rs12053390:rs1395;rs12053390:rs35686293:rs12053390:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs74630263:rs76476582:rs1395:rs4665377;rs1395:2:27498734_ACCCCCG_A",6]
["ENSG00000138074","SLC5A6",2,27422455,27435826,-1,"protein_coding",8884,"SLC5A6",0.571968337581082,-0.400099261,34,22.3,272,{"v":4.48883e-22,"d":"4.49E-22"},{"v":1.13875E-17,"d":"1.14E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":9e-77,"d":"9.00E-77"},"rs1395;rs12053390;rs4665377;rs35686293;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs8179219;2:27694905_CA_C;rs62138973;rs2580757;rs1260326;2:27739880_CT_C;rs35686293:rs76476582:rs4665377;rs12053390:rs12053390:rs8179219:rs780110;rs7423104:rs80051818:rs780110;rs7423104:rs1260326:rs74630263:rs2580757:rs1395:rs1395;rs12053390:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558",6]
["ENSG00000138085","ATRAID",2,27434895,27440046,1,"protein_coding",51374,"ATRAID",0.00791394898030435,"NA",23,15.27,279,{"v":2.34859e-32,"d":"2.35E-32"},{"v":5.3045e-26,"d":"5.30E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7e-87,"d":"7.00E-87"},"rs1395;rs12053390;rs4665377;rs35686293;rs2580757;rs74630263;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;2:27694905_CA_C;rs1260326;rs3817588;rs74340299;rs201353310;rs78653657;rs74974644;rs13016086;rs11682583;rs35686293:rs76476582:rs4665377;rs12053390:rs12053390:rs8179219:rs780110;rs7423104:rs80051818:rs780110;rs7423104:rs1260326:rs74630263:rs2580757:rs1395:rs1395;rs12053390:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs74340299:rs34796799:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558",6]
["ENSG00000084774","CAD",2,27440258,27466811,1,"protein_coding",790,"CAD",0.999999701880854,-0.710759294,47,15.27,257,{"v":1.82619e-25,"d":"1.83E-25"},{"v":9.08683e-20,"d":"9.09E-20"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs4665377;rs1395;rs12053390;rs35686293;rs8179219;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;2:27694905_CA_C;rs1260326;rs35686293:rs76476582:rs2580757:rs780110;rs7423104:rs80051818:rs8179219:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs34796799:rs4665377;rs12053390:rs12053390:rs780110;rs7423104:rs1260326:rs74630263:rs1395;rs12053390:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs74340299:rs77535061;rs76476582:rs4665377;rs12053390:rs149996558:rs1395:rs556013357:rs780110;rs556013357:rs780110:rs142398019",6]
["ENSG00000115194","SLC30A3",2,27476552,27498685,-1,"protein_coding",7781,"SLC30A3",0.64608387237045,-0.660463482,48,15.72,1,{"v":2.22523e-09,"d":"2.23E-09"},{"v":7.40729e-24,"d":"7.41E-24"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs1395;rs12053390;rs4665377;rs76476582;rs74630263;2:27498734_ACCCCCG_A;rs74340299;rs34796799;rs77535061;rs149996558;rs67086575;rs35686293:rs76476582:rs1395;rs12053390:rs1395:rs4665377;rs1395:rs12053390:rs77535061;rs76476582:rs34796799:rs8179219:rs4665377;rs12053390:rs74340299:rs780110;rs556013357;rs7423104:rs780110;rs556013357:rs780110:rs74630263:rs80051818:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs142398019:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs2580757",6]
["ENSG00000163793","DNAJC5G",2,27498289,27504367,1,"protein_coding",285126,"DNAJC5G",3.97478941010456E-3,-0.706717729,28,15.72,9,{"v":3.7699e-05,"d":"3.77E-05"},0.0236178,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs4665377;rs1395;rs12053390;rs74630263;2:27498734_ACCCCCG_A;rs74340299;rs34796799;rs77535061;rs76476582;rs149996558;rs201353310;rs7423104;rs35686293:rs76476582:rs1395;rs12053390:rs1395:rs4665377;rs1395:rs12053390:rs77535061;rs76476582:rs34796799:rs8179219:rs4665377;rs12053390:rs74340299:rs780110;rs556013357;rs7423104:rs780110;rs556013357:rs780110:rs74630263:rs80051818:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs142398019:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs2580757",6]
["ENSG00000138100","TRIM54",2,27505260,27530307,1,"protein_coding",57159,"TRIM54",{"v":8.24707898322991E-7,"d":"8.25E-07"},-1.053267254,46,15.72,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs12053390;2:27498734_ACCCCCG_A;rs4665377;rs1395;rs74340299;rs34796799;rs77535061;rs76476582;rs149996558;rs8179219;rs35686293;rs78653657;rs35686293:rs76476582:rs2580757:rs4665377;rs12053390:rs1395;rs12053390:rs4665377;rs1395:rs12053390:rs8179219:rs780110;rs556013357;rs7423104:rs74630263:rs80051818:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs34796799:rs780110;rs556013357:rs780110:rs142398019:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs1395",6]
["ENSG00000163794","UCN",2,27530268,27531313,-1,"protein_coding",7349,"UCN",0.517240162953561,-0.107138113,18,9.058,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.7e-13,"d":"3.70E-13"},"rs4665377;rs8179219;rs1395;rs12053390;rs35686293;rs74340299;rs78653657;rs35686293:rs76476582:rs2580757:rs1395:rs1395;rs12053390:rs4665377",6]
["ENSG00000115204","MPV17",2,27532360,27548547,-1,"protein_coding",4358,"MPV17",{"v":1.10286841801097E-8,"d":"1.10E-08"},-0.205368529,26,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":9e-77,"d":"9.00E-77"},"rs4665377;rs8179219;rs1395;rs12053390;rs35686293;rs74340299;rs78653657;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs76476582;rs12053390:rs1395:rs4665377;rs1395:rs4665377;rs12053390:rs74630263:rs12053390:rs77535061;rs76476582:rs34796799:rs8179219:rs74340299:rs4665377:rs35686293:rs74340299;rs78653657:rs780110;2:27498734_ACCCCCG_A:rs780110;rs7423104:rs780110;rs556013357:rs780110:rs142398019:rs2580757:rs76476582:rs4665377;rs12053390:rs149996558:rs80051818:rs35686293;rs115640879:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs7423104:rs780110;2:27498734_ACCCCCG_A:rs3817588:rs74630263;rs11682583:rs780110;2:27498734_ACCCCCG_A:rs62138973:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs201353310:rs201353310;rs7423104:2:27498734_ACCCCCG_A",6]
["ENSG00000115207","GTF3C2",2,27548716,27579868,-1,"protein_coding",2976,"GTF3C2",0.999786435918561,-0.837016421,47,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs4665377;rs1395;rs12053390;rs8179219;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs76476582;rs80051818;rs35686293;rs115640879;rs34796799;rs142398019;rs12053390:rs1395;rs12053390:rs35686293:rs8179219:rs80051818:rs780110;rs7423104:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs113160276:rs58199976;rs13013484;rs202049562;2:27832736_CA_C;rs4665386:rs77200710;2:28003616_TA_T:rs201353310:rs12053390:rs74630263:rs780110;rs556013357:rs780110:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs74340299:rs780110;2:27498734_ACCCCCG_A:rs7423104:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs34796799:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs62138973:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs4665377;rs1395:2:27498734_ACCCCCG_A:rs4665377;rs12053390:rs149996558:rs780110;2:27498734_ACCCCCG_A:rs535914125:rs1728918:rs67086575:rs780110;2:27498734_ACCCCCG_A:2:27694905_CA_C:rs35686293;rs115640879:rs2178198:rs1870325;rs4665386:rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061",6]
["ENSG00000115211","EIF2B4",2,27587219,27593353,-1,"protein_coding",8890,"EIF2B4",0.832609528731968,-0.214235303,34,18.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs8179219;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs142398019;rs80051818;rs76476582;2:27694905_CA_C;rs1260326;rs74630263:rs780110;rs7423104:rs80051818:rs8179219:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs34796799:rs780110;rs7423104:rs780110;rs556013357:rs780110;2:27498734_ACCCCCG_A:rs780110:rs4665377;rs1395;rs12053390:rs1395;rs12053390:rs4665377;rs1395:rs35686293:rs76476582:rs12053390:rs77535061;rs76476582:rs74340299:rs3817588:rs74630263;rs11682583:rs780110;2:27498734_ACCCCCG_A:rs201353310:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs62138973:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:2:27498734_ACCCCCG_A:rs4665377;rs12053390:rs149996558:rs7423104:rs535914125:rs1728918:rs67086575:2:27694905_CA_C:rs2178198:rs1870325;rs4665386:rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061",6]
["ENSG00000115234","SNX17",2,27593389,27599995,1,"protein_coding",9784,"SNX17",0.686180301198043,-0.681943317,33,18.47,258,{"v":1.17643e-13,"d":"1.18E-13"},{"v":2.00912e-09,"d":"2.01E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs8179219;rs142398019;rs80051818;rs76476582;2:27694905_CA_C;rs1260326;rs74630263;rs201353310;rs1395;rs12053390;rs4665377;2:27739880_CT_C;rs113160276;rs11682583;rs4665985;rs77200710;2:28003616_TA_T;rs67798437;rs74630263:rs780110;rs7423104:rs80051818:rs8179219:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs34796799:rs780110;rs7423104:rs780110;rs556013357:rs780110;2:27498734_ACCCCCG_A:rs780110:rs4665377;rs12053390:rs1395;rs12053390:rs4665377;rs1395:rs35686293:rs76476582:rs12053390:rs77535061;rs76476582:rs74340299:rs3817588:rs74630263;rs11682583:rs780110;2:27498734_ACCCCCG_A:rs201353310:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs62138973:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:2:27498734_ACCCCCG_A:rs4665377;rs12053390:rs149996558:rs7423104:rs535914125:rs1728918:rs67086575:2:27694905_CA_C:rs2178198:rs1870325;rs4665386:rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061",6]
["ENSG00000163795","ZNF513",2,27600098,27603657,-1,"protein_coding",130557,"ZNF513",0.940738428263313,"NA",29,18.47,67,{"v":3.61445e-05,"d":"3.61E-05"},0.0342333,"GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":9e-77,"d":"9.00E-77"},"rs8179219;rs80051818;rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs76476582;2:27694905_CA_C;rs1260326;rs74630263;rs74340299;rs3817588;rs58199976;rs202049562;2:27832736_CA_C;rs13013484;rs4665386;rs7423104:rs8179219:rs780110;2:27498734_ACCCCCG_A:rs1728918:rs780110;2:27498734_ACCCCCG_A:rs77535061;rs76476582:rs74630263:rs780110;rs7423104:rs780110;rs556013357:rs780110:rs201353310:rs4665377;rs1395;rs12053390:rs12053390:rs74340299:rs80051818:rs35686293;rs115640879:rs34796799:rs556013357:rs142398019:rs76476582:rs1260326:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs2178198:rs1870325;rs4665386:rs78653657",6]
["ENSG00000115241","PPM1G",2,27604061,27632554,-1,"protein_coding",5496,"PPM1G",0.996010385533881,-0.482626092,65,12.85,305,{"v":1.94157e-13,"d":"1.94E-13"},{"v":1.67809e-09,"d":"1.68E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":7e-87,"d":"7.00E-87"},"rs76476582;rs780110;rs556013357;2:27694905_CA_C;2:27498734_ACCCCCG_A;rs7423104;rs8179219;rs1260326;rs74630263;rs74340299;rs535914125;rs1728918;rs77535061;rs1395;rs12053390;rs4665377;rs80051818;2:27739880_CT_C;rs67798437;rs201353310;rs2178198;rs7423104:rs780110:rs7423104:rs74630263:rs8179219:rs76476582:rs74340299:rs780110;2:27498734_ACCCCCG_A:rs780110;rs556013357:rs535914125:rs780110;rs7423104:rs80051818:rs556013357:rs35686293;rs115640879:rs34796799:rs142398019:rs1260326:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs201353310:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs780110;2:27498734_ACCCCCG_A:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs2178198:rs1870325;rs4665386:rs78653657",6]
["ENSG00000115216","NRBP1",2,27650657,27665126,1,"protein_coding",29959,"NRBP1",0.999548511025196,-1.389706011,47,14.1,392,{"v":1.48664E-19,"d":"1.49E-19"},{"v":1.00894E-14,"d":"1.01E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104;rs74630263;2:27694905_CA_C;rs8179219;rs77535061;rs76476582;rs3817588;rs1395;rs12053390;rs4665377;rs80051818;rs1260326;rs1728918;rs11682583;2:27739880_CT_C;rs67798437;rs201353310;rs77200710;rs4665985;rs113160276;rs67086575;2:28003616_TA_T;rs8179219:rs80051818:rs780110;rs7423104:rs76476582:rs780110;rs7423104:rs1260326:rs780110:rs7423104:rs74630263:rs74340299:rs780110;2:27498734_ACCCCCG_A:rs780110;rs556013357:rs535914125:rs35686293;rs115640879:rs780110;2:27498734_ACCCCCG_A:rs62138973:rs780110;2:27498734_ACCCCCG_A:rs3817588:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs58199976;rs202049562;2:27832736_CA_C:rs67798437;rs201353310:rs77200710;rs4665985:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs201353310:rs34796799:rs77200710:rs201353310;rs7423104:rs4665377;rs12053390:rs12053390:rs77535061;rs76476582:rs74630263;rs11682583:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs556013357:rs142398019:rs202049562:rs67086575:2:27694905_CA_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs2178198:rs1870325;rs4665386:rs78653657",6]
["ENSG00000157992","KRTCAP3",2,27665233,27669348,1,"protein_coding",200634,"KRTCAP3",0.0445235342133754,"NA",29,10.57,245,{"v":7.8778e-12,"d":"7.88E-12"},{"v":1.02369E-7,"d":"1.02E-07"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs780110;rs556013357;2:27694905_CA_C;2:27498734_ACCCCCG_A;rs7423104;rs8179219;rs77535061;rs76476582;rs3817588;rs74630263;rs11682583;rs1395;rs12053390;rs80051818;rs1260326;2:27739880_CT_C;rs67798437;rs201353310;rs8179219:rs780110;2:27498734_ACCCCCG_A:rs780110;rs7423104:rs780110;rs556013357:rs780110:rs142398019:rs7423104:rs74630263:rs76476582:rs74340299:rs535914125:rs780110;2:27498734_ACCCCCG_A:rs1728918:rs77535061;rs76476582:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs67798437;rs201353310:rs201353310:rs201353310;rs7423104:rs62138973:rs77200710:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs80051818:rs556013357:rs35686293;rs115640879:rs34796799:rs780110;rs7423104:rs1260326:rs202049562:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs67086575:rs780110;2:27498734_ACCCCCG_A:2:27694905_CA_C:rs3817588:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs2178198:rs1870325;rs4665386:rs78653657",6]
["ENSG00000138002","IFT172",2,27667238,27712656,-1,"protein_coding",26160,"IFT172",{"v":2.29011817971014E-18,"d":"2.29E-18"},-0.505254909,82,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs780110;rs556013357;2:27694905_CA_C;2:27498734_ACCCCCG_A;rs7423104;rs8179219;rs77535061;rs76476582;rs3817588;rs74630263;rs11682583;rs67086575;rs62138973;rs35686293;rs115640879;rs7423104:rs780110;rs556013357:rs780110;2:27498734_ACCCCCG_A:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs201353310:rs34796799:rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs7423104:rs74340299:rs780110:rs201353310;rs7423104:rs62138973:rs77200710:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs76476582:rs202049562:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs80051818:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs142398019:rs1260326:rs7423104:rs74630263:rs535914125:rs1728918:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs780110;2:27498734_ACCCCCG_A:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs2178198:rs1870325;rs4665386:rs78653657:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640;rs6722113:rs11889865:rs6722113:rs7349418:rs35937640:rs4666052",6]
["ENSG00000115226","FNDC4",2,27714750,27718112,-1,"protein_coding",64838,"FNDC4",0.759219015798597,"NA",28,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs780110;rs556013357;2:27498734_ACCCCCG_A;rs35686293;rs115640879;rs8179219;2:27694905_CA_C;rs7423104;rs62138973;rs7423104:rs780110;rs556013357:rs780110;2:27498734_ACCCCCG_A:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs201353310:rs34796799:rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs7423104:rs74340299:rs780110:rs201353310;rs7423104:rs62138973:rs77200710:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs76476582:rs202049562:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs80051818:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs142398019:rs1260326:rs7423104:rs74630263:rs535914125:rs1728918:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs780110;2:27498734_ACCCCCG_A:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs2178198:rs1870325;rs4665386:rs78653657:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640;rs6722113:rs11889865:rs6722113:rs7349418:rs35937640:rs4666052",6]
["ENSG00000084734","GCKR",2,27719709,27746554,1,"protein_coding",2646,"GCKR",{"v":3.58392509874806e-16,"d":"3.58E-16"},-0.155697744,79,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs780110;rs556013357;2:27498734_ACCCCCG_A;rs35686293;rs115640879;rs8179219;2:27694905_CA_C;rs7423104;rs62138973;rs1260326;rs3817588;2:27739880_CT_C;2:27738632_ATTTT_A;rs34796799;rs80051818;rs74340299;rs4665985;rs58199976;rs202049562;2:27832736_CA_C;rs67798437;rs201353310;rs77200710;rs7423104:rs780110;rs556013357:rs780110;2:27498734_ACCCCCG_A:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs201353310:rs34796799:rs2178198:rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs7423104:rs74340299:rs780110:rs80051818:rs76476582:rs1260326:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs201353310;rs7423104:rs62138973:rs77200710:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs202049562:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs556013357:rs780110;2:27498734_ACCCCCG_A:rs35686293;rs115640879:rs142398019:rs7423104:rs74630263:rs535914125:rs1728918:rs67086575:rs780110;2:27498734_ACCCCCG_A:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs1870325;rs4665386:rs78653657:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640;rs6722113:rs11889865:rs6722113:rs7349418:rs35937640:rs4666052",6]
["ENSG00000233438","AC109829.1",2,27760253,27790011,1,"protein_coding","NA","NA","NA","NA",92,12.33,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs1260326;2:27739880_CT_C;rs3817588;rs780110;rs74340299;rs4665985;rs58199976;rs202049562;2:27832736_CA_C;rs67798437;rs201353310;rs77200710;rs78653657;rs13013484;rs4665386;2:27766414_CA_C;rs7423104;rs11682583;2:27786252_CTTTTTTTTTT_C;rs77535061;rs80051818:rs556013357:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs780110;2:27498734_ACCCCCG_A:rs8179219:rs35686293;rs115640879:rs34796799:rs780110;rs556013357:rs780110:rs142398019:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs74630263:rs780110;2:27498734_ACCCCCG_A:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs74340299:rs4665985:rs58199976;2:27832736_CA_C:rs67798437;rs201353310:rs77200710;rs4665985:rs201353310:rs74340299;rs78653657:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs4666052",6]
["ENSG00000221843","C2orf16",2,27799389,27805588,1,"protein_coding",84226,"C2orf16",{"v":3.91661992667067e-17,"d":"3.92E-17"},-0.329746802,28,17.52,3,{"v":4.21915e-06,"d":"4.22E-06"},0.0141403,"GTEx/v8/Liver","-","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs58199976;rs202049562;2:27832736_CA_C;rs77200710;rs4665985;rs201353310;rs7423104;rs67798437;rs77535061;rs34796799;rs3817588;rs80051818:rs556013357:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs780110;2:27498734_ACCCCCG_A:rs8179219:rs35686293;rs115640879:rs34796799:rs780110;rs556013357:rs780110:rs142398019:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs74630263:rs780110;2:27498734_ACCCCCG_A:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs74340299:rs4665985:rs58199976;2:27832736_CA_C:rs67798437;rs201353310:rs77200710;rs4665985:rs201353310:rs74340299;rs78653657:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs4666052",6]
["ENSG00000243943","ZNF512",2,27805897,27858041,1,"protein_coding",84450,"ZNF512",0.949146986047491,-1.279253328,110,18.65,6,{"v":8.67923e-05,"d":"8.68E-05"},0.0461625,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs77535061;rs67798437;rs201353310;rs58199976;rs202049562;2:27832736_CA_C;rs77200710;rs4665985;rs34796799;rs7423104;rs62138973;rs4665386;rs549596761;rs2141371;rs13013484;2:28003616_TA_T;rs780110;rs556013357;2:27498734_ACCCCCG_A:rs780110:rs35686293;rs115640879:rs8179219:rs780110;2:27694905_CA_C;2:27498734_ACCCCCG_A:rs780110;2:27498734_ACCCCCG_A;rs7423104:rs62138973:rs780110;2:27498734_ACCCCCG_A:rs4665377;rs1395;rs12053390:rs12053390:rs780110;rs7423104:rs74340299:rs780110;rs556013357:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs67798437;rs201353310:rs201353310:rs201353310;rs7423104:rs80051818:rs556013357:rs34796799:rs142398019:rs76476582:rs1260326:rs67086575:2:27694905_CA_C:rs7423104:rs74630263:rs535914125:rs1728918:rs77200710:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs202049562:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs7349418:rs35937640:rs11889865:rs4666052",6]
["ENSG00000176714","CCDC121",2,27848506,27851879,-1,"protein_coding",79635,"CCDC121",{"v":9.72713578876563e-05,"d":"9.73E-05"},-0.266319334,42,18.65,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs58199976;rs202049562;2:27832736_CA_C;rs67798437;rs201353310;rs77200710;rs4665985;rs7423104;rs62138973;rs4665386;rs549596761;rs2141371;rs780110;rs556013357;2:27694905_CA_C;2:27498734_ACCCCCG_A;rs7423104:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs8179219:rs780110:rs780110;2:27498734_ACCCCCG_A:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs35686293;rs115640879:rs780110;2:27498734_ACCCCCG_A:rs80051818:rs556013357:rs780110;rs7423104:rs34796799:rs780110;rs556013357:rs142398019:rs76476582:rs1260326:rs74630263:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs201353310:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs7423104:rs74340299:rs535914125:rs1728918:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:rs4665386:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs77200710;2:28003616_TA_T:rs2178198:rs1870325;rs4665386:rs78653657:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs7349418:rs35937640:rs11889865:rs4666052",6]
["ENSG00000198522","GPN1",2,27851114,27874375,1,"protein_coding",11321,"GPN1",0.0049035919998219,-0.238154635,54,14.13,246,{"v":7.93394e-08,"d":"7.93E-08"},0.000297808,"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs67798437;rs201353310;rs58199976;rs202049562;2:27832736_CA_C;rs7423104;rs62138973;rs77200710;rs4665386;rs549596761;rs2141371;rs13013484;2:28003616_TA_T;rs113160276;rs76476582;rs4665985;rs780110;rs556013357;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27739880_CT_C;rs7423104:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs8179219:rs780110:rs780110;2:27498734_ACCCCCG_A:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs35686293;rs115640879:rs780110;2:27498734_ACCCCCG_A:rs80051818:rs556013357:rs780110;rs7423104:rs34796799:rs780110;rs556013357:rs142398019:rs76476582:rs1260326:rs74630263:rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs201353310:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs7423104:rs74340299:rs535914125:rs1728918:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs74340299;rs78653657:rs13013484;2:27832736_CA_C:rs4665386:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs77200710;2:28003616_TA_T:rs2178198:rs1870325;rs4665386:rs78653657:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs7349418:rs35937640:rs11889865:rs4666052",6]
["ENSG00000119760","SUPT7L",2,27873679,27886676,-1,"protein_coding",9913,"SUPT7L",0.833193338587633,-0.966218532,23,12.86,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":7e-87,"d":"7.00E-87"},"rs58199976;rs13013484;rs202049562;2:27832736_CA_C;rs4665386;rs77200710;2:28003616_TA_T;rs113160276;rs201353310;rs76476582;rs2178198;rs4665377;rs1395;rs12053390:rs1395:rs1395;rs12053390:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs780110:rs7423104:rs74630263:rs8179219:rs780110;2:27694905_CA_C;rs7423104:rs780110;rs556013357:rs12053390:rs80051818:rs76476582:rs1260326:rs74340299:rs35686293;rs115640879:rs780110;2:27498734_ACCCCCG_A:rs780110;2:27498734_ACCCCCG_A:rs62138973:rs780110;2:27498734_ACCCCCG_A:rs4666052:rs556013357:rs34796799:rs142398019:rs535914125:rs1728918:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs67086575:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs58199976;2:27832736_CA_C:rs67798437;rs201353310:rs77200710;rs4665985:rs201353310:rs74340299;rs78653657:rs201353310;rs7423104:rs77200710:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640:rs11889865",6]
["ENSG00000163798","SLC4A1AP",2,27886338,27917840,1,"protein_coding",22950,"SLC4A1AP",{"v":7.73999085415032e-07,"d":"7.74E-07"},-0.546764453,20,15.03,179,{"v":2.84507E-9,"d":"2.85E-09"},{"v":8.71618E-6,"d":"8.72E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":7e-87,"d":"7.00E-87"},"rs76476582;rs201353310;rs58199976;rs13013484;rs202049562;2:27832736_CA_C;rs4665386;rs77200710;2:28003616_TA_T;rs2178198;rs1870325;rs78653657;rs150818831;rs67798437;rs7423104;rs2141371;rs6714106;rs199780998;rs780110;rs113160276;rs4665377;rs1395;rs12053390:rs1395:rs1395;rs12053390:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs780110:rs7423104:rs74630263:rs8179219:rs780110;2:27694905_CA_C;rs7423104:rs780110;rs556013357:rs12053390:rs80051818:rs76476582:rs1260326:rs74340299:rs35686293;rs115640879:rs780110;2:27498734_ACCCCCG_A:rs780110;2:27498734_ACCCCCG_A:rs62138973:rs780110;2:27498734_ACCCCCG_A:rs4666052:rs556013357:rs34796799:rs142398019:rs535914125:rs1728918:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs67086575:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs4665985:rs58199976;2:27832736_CA_C:rs67798437;rs201353310:rs77200710;rs4665985:rs201353310:rs74340299;rs78653657:rs201353310;rs7423104:rs77200710:rs4665386:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640:rs11889865",6]
["ENSG00000205334","AC074091.13",2,27928653,27938599,-1,"protein_coding",100129995,"LINC01460","NA","NA",17,18.44,40,{"v":1.69114e-05,"d":"1.69E-05"},0.0188373,"GTEx/v8/Artery_Aorta","+","Yes","Promoter_anchored_loops:Adult_Cortex:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-33,"d":"3.90E-33"},"rs201353310;rs150818831;rs35686293;rs115640879;rs77200710;2:28003616_TA_T;rs1870325;rs4665386;rs58199976;rs13013484;rs202049562;2:27832736_CA_C;rs6722113:rs11889865:rs35937640;rs6722113:rs74974644:rs34796799:rs13013484;rs4665386:rs13013484;rs1870325:rs58199976;rs1870325:rs7349418:rs35937640:rs764054216:2:28003616_TA_T:rs1870325:rs1870325;rs11691385:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs4666052:rs2178198:rs1317580:rs1870325;rs4665386:rs58199976;rs13013484:2:28003616_TA_T;rs1317580:rs201353310:rs13013484:rs13013484;rs6714106:rs13013484;rs199780998;rs6714106:rs6714106:rs1870325;rs57333567:rs57333567:2:28206809_CT_C:rs115640879:rs111882076:rs4666042:rs55807911",6]
["ENSG00000243147","MRPL33",2,27994584,28210954,1,"protein_coding",9553,"MRPL33",0.749164756585824,-0.22012956,207,19.66,296,{"v":3.59543e-09,"d":"3.60E-09"},{"v":2.0615e-05,"d":"2.06E-05"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex:Bladder:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.9e-33,"d":"3.90E-33"},"rs13013484;rs1870325;2:28003616_TA_T;rs58199976;rs74974644;rs34796799;rs4665386;rs764054216;rs11691385;rs6714106;rs13016086;rs199780998;rs57333567;2:28206809_CT_C;rs202049562;2:27832736_CA_C;rs201353310;rs7423104;rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs202049562:rs58199976;rs13013484:rs13013484;rs1870325:rs13013484;rs4665386:rs1870325:rs1870325;rs11691385:rs1870325;rs11691385:rs13013484;rs6714106:rs7349418:rs35937640:rs4666052:rs11889865:rs1870325;rs6714106:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs58199976;rs4665386:rs78653657:rs764054216:2:28003616_TA_T:rs13013484;rs6714106:rs6714106:rs1870325;rs57333567:rs57333567:2:28206809_CT_C:rs2178198:rs34796799:rs115640879:rs35937640;rs6722113:rs6722113:rs4666042:rs55807911",6]
["ENSG00000268656","AC110084.1",2,27998851,28009186,-1,"protein_coding","NA","NA","NA","NA",24,19.66,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.7e-78,"d":"2.70E-78"},"rs58199976;rs13013484;rs1870325;rs74974644;rs34796799;rs4665386;rs764054216;2:28003616_TA_T;rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A:rs1260326;2:27739880_CT_C:rs3817588:rs780110:rs34796799:rs80051818:rs13013484;rs199780998;rs6714106:rs1870325;rs57333567;rs11691385:rs2178198:rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs202049562;2:27832736_CA_C;rs4665386:rs58199976;rs13013484:rs78653657:rs58199976;rs202049562:rs1870325;rs6714106:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640;rs6722113:rs11889865:rs6722113:rs7349418:rs35937640:rs4666052:rs1317580:2:28003616_TA_T;rs1317580:rs13013484;rs1870325:2:28003616_TA_T:rs13013484:rs58199976;rs1870325:rs74974644:rs13013484;rs4665386:rs1870325:rs1870325;rs11691385:rs13013484;rs6714106:rs6714106:rs1870325;rs57333567:rs57333567:2:28206809_CT_C:rs115640879:rs111882076:rs4666042:rs55807911",6]
["ENSG00000171174","RBKS",2,28004231,28113965,-1,"protein_coding",64080,"RBKS",{"v":1.93197572918752E-5,"d":"1.93E-05"},-0.689745423,139,19.66,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-33,"d":"3.90E-33"},"rs34796799;rs13013484;rs1870325;rs58199976;rs74974644;rs764054216;rs4665386;2:28003616_TA_T;rs11691385;rs6714106;rs13016086;rs199780998;rs57333567;rs6714106:rs1870325:rs1870325;rs11691385:rs13013484;rs1870325:rs13013484;rs6714106:rs13016086;rs74974644:2:28003616_TA_T:rs1870325;rs11691385:rs1870325;rs6714106:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640;rs6722113:rs11889865:rs6722113:rs34796799:rs7349418:rs35937640:rs4666052:rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs202049562;2:27832736_CA_C;rs4665386:rs58199976;rs13013484:rs78653657:rs58199976;rs202049562:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs58199976;rs1870325:rs74974644:rs13013484;rs4665386:rs764054216:rs57333567:2:28206809_CT_C:rs115640879:rs111882076:rs4666042:rs55807911",6]
["ENSG00000158019","BRE",2,28112808,28561768,1,"protein_coding",9577,"BRE",0.279976282823241,"NA",224,16.05,2,{"v":5.80945e-05,"d":"5.81E-05"},0.00582956,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-33,"d":"3.90E-33"},"rs13013484;rs1870325;rs199780998;rs6714106;rs57333567;rs11691385;2:28003616_TA_T;2:28206809_CT_C;rs2178198;rs34796799;rs115640879;rs13016086;rs74974644;rs937813;rs11889865;rs111882076;rs6722113;rs35937640;rs4666042;rs55807911;rs7349418;rs4666052;rs1870325:rs1870325;rs11691385:rs13013484;rs1870325:rs13013484;rs6714106:rs13016086;rs74974644:2:28003616_TA_T:rs13013484;rs6714106:rs1870325;rs11691385:rs1870325;rs6714106:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs35937640;rs6722113:rs11889865:rs6722113:rs34796799:rs7349418:rs35937640:rs4666052:rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs202049562;2:27832736_CA_C;rs4665386:rs58199976;rs13013484:rs78653657:rs58199976;rs202049562:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs58199976;rs1870325:rs74974644:rs13013484;rs4665386:rs764054216:rs57333567:2:28206809_CT_C:rs115640879:rs111882076:rs4666042:rs55807911",6]
["ENSG00000075426","FOSL2",2,28615315,28640179,1,"protein_coding",2355,"FOSL2",0.925334261981773,-2.20415963,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Aorta:Bladder:Left_Ventricle:Liver:Lung:Pancreas:Psoas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":9e-77,"d":"9.00E-77"},"rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs13013484;rs202049562:rs58199976;rs13013484:rs34796799:rs13013484;rs1870325:2:28003616_TA_T:rs13013484:rs58199976;rs1870325:rs764054216:rs13013484;rs1870325;rs4665386:rs1870325;rs57333567;rs11691385:rs1870325:rs13013484;rs199780998;rs6714106:rs58199976;rs202049562;2:27832736_CA_C;rs4665386:rs78653657:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs74974644:rs1870325;rs11691385:rs13013484;rs6714106:rs13016086;rs74974644:rs80051818:rs556013357:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs780110;2:27498734_ACCCCCG_A:rs8179219:rs780110;rs556013357:rs780110:rs142398019:rs76476582:rs780110;2:27694905_CA_C;rs7423104:rs1260326:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs780110;2:27498734_ACCCCCG_A:rs77200710;rs4665985:rs58199976;2:27832736_CA_C:rs67798437;rs201353310:rs201353310;rs7423104:rs77200710:rs58199976;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs113160276:rs6714106:rs1870325;rs57333567:rs1870325;rs6714106:rs57333567:2:28206809_CT_C:rs115640879:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs11889865:rs111882076:rs6722113:rs35937640;rs6722113:rs7349418:rs35937640:rs4666052:rs74630263:rs77535061;rs76476582:rs3817588:rs74630263;rs11682583:rs202049562:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs4666042:rs55807911",6]
["ENSG00000163803","PLB1",2,28680012,28866654,1,"protein_coding",151056,"PLB1",{"v":1.9931529274349E-56,"d":"1.99E-56"},0.411383907,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7e-87,"d":"7.00E-87"},"rs67798437;rs201353310:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs201353310:rs34796799:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325:rs1870325;rs11691385:rs13013484;rs1870325:rs13013484;rs1870325;rs6714106:rs13016086;rs74974644:2:28003616_TA_T:rs13013484;rs199780998;rs6714106:rs1870325;rs57333567;rs11691385:rs202049562:rs201353310;rs7423104:rs202049562;2:27832736_CA_C:2:27832736_CA_C:rs67798437:rs77200710:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs13013484;2:27832736_CA_C;rs4665386:rs58199976;rs13013484:rs78653657:rs58199976;rs202049562:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs58199976;rs1870325:rs74974644:rs13013484;rs4665386:rs764054216:rs6714106:rs1870325;rs57333567:rs1870325;rs6714106:rs115640879:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs780110;rs556013357;2:27694905_CA_C;2:27498734_ACCCCCG_A;rs7423104:rs8179219:rs780110:rs780110;2:27498734_ACCCCCG_A:rs67086575:rs780110;2:27498734_ACCCCCG_A:rs62138973:2:27694905_CA_C:rs780110;2:27498734_ACCCCCG_A:rs13013484;2:27832736_CA_C:2:27766414_CA_C:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs113160276:rs76476582:rs57333567:2:28206809_CT_C:rs35937640;rs6722113:rs11889865:rs6722113:rs35937640:rs4666052:rs1260326:rs3817588:rs1260326;2:27739880_CT_C:2:27738632_ATTTT_A:2:27739880_CT_C:rs80051818:rs74340299:rs4665985:rs74340299;rs78653657:rs7349418",6]
["ENSG00000213639","PPP1CB",2,28974506,29025806,1,"protein_coding",5500,"PPP1CB",0.997194974203565,0.001839166,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.7e-47,"d":"4.70E-47"},"rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs74340299:rs780110;rs556013357:rs780110:rs8179219:rs35686293;rs115640879:rs780110;2:27498734_ACCCCCG_A:rs780110;2:27694905_CA_C;rs7423104:rs62138973:rs780110;2:27498734_ACCCCCG_A:rs201353310:rs150818831:rs77200710;2:28003616_TA_T:rs74974644:rs34796799:rs13013484;rs1870325;rs4665386:rs13013484;rs1870325:rs58199976;rs13013484;rs1870325:rs764054216:2:28003616_TA_T:rs4666052:rs1870325;rs6714106:rs1870325;rs57333567;rs11691385:rs13016086;rs74974644:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs67086575:2:27694905_CA_C:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs67798437;rs201353310:rs201353310;rs7423104:rs77200710:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs4665386:rs113160276:rs76476582:rs2178198:rs1870325;rs4665386:rs78653657:rs58199976:rs58199976;rs13013484:rs58199976;rs202049562:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs1870325:rs1870325;rs11691385:rs13013484;rs6714106:rs13013484;rs199780998;rs6714106:rs6714106:rs1870325;rs57333567:rs57333567:2:28206809_CT_C:rs35937640;rs6722113:rs11889865:rs6722113:rs7349418:rs35937640",6]
["ENSG00000163806","SPDYA",2,29005383,29073477,1,"protein_coding",245711,"SPDYA",0.166884223990281,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.7e-47,"d":"4.70E-47"},"rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs67798437;rs201353310:rs201353310:rs201353310;rs7423104:rs62138973:rs77200710:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;2:27832736_CA_C:rs549596761:rs2141371:rs58199976;rs13013484;rs4665386:rs77200710;2:28003616_TA_T:rs113160276:rs76476582:rs150818831:rs35686293;rs115640879:rs1870325;rs4665386:rs58199976:rs58199976;rs13013484:rs78653657:rs58199976;rs202049562:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs34796799:rs13013484;rs1870325:2:28003616_TA_T:rs13013484:rs58199976;rs1870325:rs74974644:rs13013484;rs1870325;rs4665386:rs764054216:rs1870325:rs1870325;rs11691385:rs13013484;rs6714106:rs13016086;rs74974644:rs13013484;rs199780998;rs6714106:rs1870325;rs57333567;rs11691385:rs1870325;rs6714106:rs199780998:rs11691385:rs937813:rs937813;rs11889865:rs13016086:rs6714106:rs1870325;rs57333567:rs57333567:2:28206809_CT_C",6]
["ENSG00000171103","TRMT61B",2,29072687,29093167,-1,"protein_coding",55006,"TRMT61B",{"v":4.00751770882134e-06,"d":"4.01E-06"},-0.602142186,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.7e-47,"d":"4.70E-47"},"rs4665377;rs1395;rs12053390:rs12053390:rs8179219:rs780110;rs556013357;2:27498734_ACCCCCG_A;rs7423104:rs74340299:rs780110;rs556013357:rs780110:rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs74974644:rs34796799:rs13013484;rs1870325;rs4665386:rs13013484;rs1870325:rs58199976;rs13013484;rs1870325:rs77200710;rs4665985:rs58199976;rs202049562;2:27832736_CA_C:rs67798437;rs201353310:rs201353310;rs7423104:rs62138973:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;2:27832736_CA_C;rs4665386:rs58199976;rs13013484:rs78653657:rs58199976",6]
["ENSG00000163811","WDR43",2,29117509,29171088,1,"protein_coding",23160,"WDR43",0.998942440488972,1.455113129,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-33,"d":"3.90E-33"},"rs74974644:rs34796799:rs13013484;rs1870325;rs4665386:rs13013484;rs1870325:rs58199976;rs13013484;rs1870325:rs201353310:rs150818831:rs35686293;rs115640879:rs77200710;2:28003616_TA_T:rs1870325;rs4665386:rs58199976:rs4665386:rs58199976;rs202049562;2:27832736_CA_C;rs4665386:rs58199976;rs13013484:rs78653657:rs58199976",6]
["ENSG00000171094","ALK",2,29415640,30144432,-1,"protein_coding",238,"ALK",0.522362516846561,-0.624899803,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":9.5e-49,"d":"9.50E-49"},"rs77200710;rs4665985:rs13013484;rs202049562;2:27832736_CA_C:rs67798437;rs201353310:rs58199976;2:27832736_CA_C:rs201353310:rs4665386:rs77200710:2:27766414_CA_C:rs201353310;rs7423104:rs202049562:rs11682583:2:27786252_CTTTTTTTTTT_C:rs77535061",6]
["ENSG00000152128","TMEM163",2,135213330,135476570,-1,"protein_coding",81615,"TMEM163",0.0672624651374226,0.397258421,0,0,14,{"v":3.24677E-8,"d":"3.25E-08"},{"v":1.60223E-14,"d":"1.60E-14"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","No","NA",{"v":4.5e-06,"d":"4.50E-06"},"rs11681659",7]
["ENSG00000082258","CCNT2",2,135675805,135716912,1,"protein_coding",905,"CCNT2",0.49810408150126,-1.291148908,0,0,13,{"v":3.95125e-06,"d":"3.95E-06"},{"v":6.72446e-18,"d":"6.72E-18"},"GTEx/v8/Artery_Aorta","+","No","NA",{"v":8.3e-06,"d":"8.30E-06"},"rs11681659",7]
["ENSG00000176601","MAP3K19",2,135722061,135805038,-1,"protein_coding",80122,"MAP3K19",{"v":3.69884742626308e-14,"d":"3.70E-14"},0.1252064,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-05,"d":"2.20E-05"},"rs11681659",7]
["ENSG00000115839","RAB3GAP1",2,135809835,135933964,1,"protein_coding",22930,"RAB3GAP1",{"v":3.66101381631237E-5,"d":"3.66E-05"},-0.439175216,2,0.534,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.3e-06,"d":"8.30E-06"},"rs11681659",7]
["ENSG00000121988","ZRANB3",2,135894486,136288806,-1,"protein_coding",84083,"ZRANB3",{"v":7.42639986547535e-15,"d":"7.43E-15"},-0.510649767,8,8.287,39,{"v":6.30127e-05,"d":"6.30E-05"},{"v":4.0053e-06,"d":"4.01E-06"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":1.5E-5,"d":"1.50E-05"},"rs11681659",7]
["ENSG00000048991","R3HDM1",2,136289025,136482840,1,"protein_coding",23518,"R3HDM1",0.00602513988409452,-0.983617194,6,21,0,"NA","NA","NA","NA","No","NA",{"v":4.5e-06,"d":"4.50E-06"},"rs11681659",7]
["ENSG00000144224","UBXN4",2,136499189,136542625,1,"protein_coding",23190,"UBXN4",0.974205695161288,-0.658500963,0,0,72,{"v":3.07575e-07,"d":"3.08E-07"},{"v":6.12378E-6,"d":"6.12E-06"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.2e-08,"d":"6.20E-08"},"rs11681659",7]
["ENSG00000115850","LCT",2,136545410,136594750,-1,"protein_coding",3938,"LCT",0.0642550168201587,0.129442028,20,12.93,0,"NA","NA","NA","NA","No","NA",{"v":2.4e-05,"d":"2.40E-05"},"rs11681659",7]
["ENSG00000076003","MCM6",2,136597196,136633996,-1,"protein_coding",4175,"MCM6",0.998482019514362,0.155094687,37,13.46,96,{"v":2.72387e-21,"d":"2.72E-21"},{"v":7.54241e-16,"d":"7.54E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","GM12878:Mesendoderm:hESC",{"v":2.1e-08,"d":"2.10E-08"},"rs11681659",7]
["ENSG00000115866","DARS",2,136664247,136743670,-1,"protein_coding",1615,"DARS",6.1199920887983E-4,0.123876255,11,13.65,92,{"v":4.34153e-06,"d":"4.34E-06"},{"v":3.69417e-08,"d":"3.69E-08"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":2.1e-08,"d":"2.10E-08"},"rs11681659",7]
["ENSG00000121966","CXCR4",2,136871919,136875735,-1,"protein_coding",7852,"CXCR4",0.427450979947767,-0.284617205,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-08,"d":"2.10E-08"},"rs11681659",7]
["ENSG00000144229","THSD7B",2,137523115,138435287,1,"protein_coding",80731,"THSD7B",{"v":5.65285413355626e-06,"d":"5.65E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":6.4e-08,"d":"6.40E-08"},"rs11681659",7]
["ENSG00000150540","HNMT",2,138721590,138773930,1,"protein_coding",3176,"HNMT",0.0967293826850996,0.562236353,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.4e-08,"d":"6.40E-08"},"rs11681659",7]
["ENSG00000144227","NXPH2",2,139428342,139537918,-1,"protein_coding",11249,"NXPH2",0.798014407186903,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.4e-08,"d":"6.40E-08"},"rs11681659",7]
["ENSG00000226894","TMPRSS11BNL",4,69054242,69083798,-1,"protein_coding",401136,"TMPRSS11BNL",0.315776901388964,0.704294788,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.8e-21,"d":"3.80E-21"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191:rs4860987:rs4860987;4:69447407_GT_G:rs368166328:rs748167110:rs4443356:rs2331416",8]
["ENSG00000185873","TMPRSS11B",4,69092371,69111438,-1,"protein_coding",132724,"TMPRSS11B",{"v":1.68050228934566e-11,"d":"1.68E-11"},0.053188955,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.8e-21,"d":"3.80E-21"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191:rs4860987:rs4860987;4:69447407_GT_G:rs368166328:rs748167110:rs4443356:rs2331416",8]
["ENSG00000083896","YTHDC1",4,69176105,69215807,-1,"protein_coding",91746,"YTHDC1",0.999999898691266,-1.324074711,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.9e-16,"d":"1.90E-16"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191",8]
["ENSG00000087128","TMPRSS11E",4,69313167,69363322,1,"protein_coding",28983,"TMPRSS11E",{"v":3.75424420546756E-5,"d":"3.75E-05"},0.26253994,118,22.5,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.9e-16,"d":"1.90E-16"},"rs34327193;rs2603187;rs1377869;rs4860309;rs9884390;rs2123886;rs34103191;rs2603152;rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191",8]
["ENSG00000197888","UGT2B17",4,69402902,69434245,-1,"protein_coding",7367,"UGT2B17",0.0102556056990611,0.903832175,94,9.889,118,{"v":2.78097e-19,"d":"2.78E-19"},{"v":5.32642E-14,"d":"5.33E-14"},"GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Liver",{"v":3.8e-21,"d":"3.80E-21"},"rs9884390;rs4860951;rs13138417;rs113786911;rs9312195;rs531187399;rs4860309;rs4860987;4:69447407_GT_G;rs62317004;rs13101504;rs34327193;rs2603187;rs2123886;rs1377869;rs34103191;rs4443356;rs2331416;rs4860987:rs4860309:rs4860987;4:69447407_GT_G:rs368166328:rs748167110:rs34103191:rs4443356:rs2331416",8]
["ENSG00000196620","UGT2B15",4,69512348,69536346,-1,"protein_coding",7366,"UGT2B15",{"v":1.92098648554063e-10,"d":"1.92E-10"},0.677329965,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":1.2E-16,"d":"1.20E-16"},"rs9884390;rs13138417;rs113786911:rs531187399:rs9884390;rs113786911:rs113786911:rs4860309:rs9884390;rs113786911;rs9312195:rs4860987;4:69447407_GT_G;rs4860951;rs62317004;rs13101504:4:69447407_GT_G;rs62317004:rs62317004:4:69447407_GT_G;rs13101504:rs4860987;rs13101504",8]
["ENSG00000109181","UGT2B10",4,69681711,69696914,1,"protein_coding",7365,"UGT2B10",{"v":5.50615564451229e-15,"d":"5.51E-15"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.8e-21,"d":"3.80E-21"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191:rs9884390;rs13138417;rs113786911:rs531187399:rs9884390;rs113786911:rs113786911:rs9884390;rs113786911;rs9312195:rs4860987;4:69447407_GT_G;rs4860951;rs62317004;rs13101504:4:69447407_GT_G;rs62317004:rs62317004:4:69447407_GT_G;rs13101504:rs4860987;rs13101504:rs4860987:rs4860987;4:69447407_GT_G:rs368166328:rs748167110:rs4443356:rs2331416:rs2603152:rs370878539:rs9884390;rs9312195:rs4860951:rs9884390;rs113786911:rs9884390;rs9312195:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195",8]
["ENSG00000135220","UGT2A3",4,69794181,69817509,-1,"protein_coding",79799,"UGT2A3",{"v":5.00169122908013e-06,"d":"5.00E-06"},0.402338316,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-18,"d":"4.90E-18"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191:rs35673206:rs2603152:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195",8]
["ENSG00000171234","UGT2B7",4,69917081,69978705,1,"protein_coding",7364,"UGT2B7",{"v":3.49679084556951e-08,"d":"3.50E-08"},0.82500636,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.8e-21,"d":"3.80E-21"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191:rs2603152:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195:rs35673206:rs4860987:rs4860987;4:69447407_GT_G:rs368166328:rs748167110:rs4443356:rs2331416",8]
["ENSG00000213759","UGT2B11",4,70065669,70080449,-1,"protein_coding",10720,"UGT2B11",{"v":3.14709815271135E-13,"d":"3.15E-13"},0.706560698,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.8e-21,"d":"3.80E-21"},"rs2603187:rs9884390;rs2123886:rs1377869:rs34327193:rs2123886:rs9884390:rs4860309:rs34103191:rs4860987:rs4860987;4:69447407_GT_G:rs368166328:rs748167110:rs4443356:rs2331416:rs35673206:rs2603152:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195",8]
["ENSG00000135226","UGT2B28",4,70146217,70160768,1,"protein_coding",54490,"UGT2B28",{"v":6.44395718165304e-08,"d":"6.44E-08"},-0.023007521,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.9e-18,"d":"4.90E-18"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs35673206:rs4860309:rs34103191:rs2603152:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195",8]
["ENSG00000156096","UGT2B4",4,70345883,70391732,-1,"protein_coding",7363,"UGT2B4",{"v":8.44718840140518e-11,"d":"8.45E-11"},0.451804371,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.9e-16,"d":"1.90E-16"},"rs2603187:rs34327193:rs9884390;rs2123886:rs2123886:rs9884390:rs1377869:rs4860309:rs34103191",8]
["ENSG00000173610","UGT2A1",4,70454135,70518965,-1,"protein_coding",10941,"UGT2A1",{"v":2.73195454586815E-11,"d":"2.73E-11"},-0.281771314,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":4.9e-18,"d":"4.90E-18"},"rs34103191:rs2603152:rs9884390:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs4860309:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195:rs35673206:rs34327193:rs2603187:rs1377869:rs9884390;rs2123886:rs2123886",8]
["ENSG00000271271","UGT2A2",4,70454135,70505360,-1,"protein_coding",574537,"UGT2A2",{"v":2.32634948326899e-07,"d":"2.33E-07"},-0.31710536,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":4.9e-18,"d":"4.90E-18"},"rs34103191:rs2603152:rs9884390:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs4860309:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195:rs35673206:rs34327193:rs2603187:rs1377869:rs9884390;rs2123886:rs2123886",8]
["ENSG00000270386","UGT2A1",4,70454912,70518967,-1,"protein_coding",10941,"UGT2A1","NA",-0.281771314,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":4.9e-18,"d":"4.90E-18"},"rs34103191:rs2603152:rs9884390:rs370878539:rs9884390;rs113786911:rs9884390;rs4860951;rs13138417;rs113786911;rs9312195:rs4860951:rs9884390;rs9312195:rs113786911:rs9884390;rs9312195:rs4860309:rs9312195:4:69382399_GTT_G:rs113786911;rs9312195:rs9884390;rs9312195:rs35673206:rs34327193:rs2603187:rs1377869:rs9884390;rs2123886:rs2123886",8]
["ENSG00000145808","ADAMTS19",5,128795958,129074376,1,"protein_coding",171019,"ADAMTS19",0.951958940870202,0.787855457,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",0.00019,"rs10075801",9]
["ENSG00000198108","CHSY3",5,129240165,129522327,1,"protein_coding",337876,"CHSY3",0.011861287143968,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",0.00019,"rs10075801",9]
["ENSG00000169567","HINT1",5,130494720,130507428,-1,"protein_coding",3094,"HINT1",0.0842644971048886,-0.379107133,0,0,11,{"v":5.47708e-05,"d":"5.48E-05"},{"v":4.93674e-09,"d":"4.94E-09"},"GTEx/v8/Heart_Left_Ventricle","-","No","NA",0.00019,"rs10075801",9]
["ENSG00000158985","CDC42SE2",5,130581186,130734140,1,"protein_coding",56990,"CDC42SE2",0.753728627374484,-0.225977482,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",0.00019,"rs10075801",9]
["ENSG00000158987","RAPGEF6",5,130759614,130970929,-1,"protein_coding",51735,"RAPGEF6",0.998026273148455,-0.743538794,0,0,16,0.000110428,{"v":5.68575e-08,"d":"5.69E-08"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-7,"d":"1.80E-07"},"5:131664516_TTATATA_T;rs10075801",9]
["ENSG00000273217","CTC-432M15.3",5,130761584,131132676,-1,"protein_coding","NA","NA",0.996763358307615,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",0.00019,"rs10075801",9]
["ENSG00000217128","FNIP1",5,130977407,131132710,-1,"protein_coding",96459,"FNIP1",0.99981944509088,-0.514581055,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",0.00019,"rs10075801",9]
["ENSG00000164398","ACSL6",5,131142683,131347936,-1,"protein_coding",23305,"ACSL6",0.088562272207543,-1.292579097,5,10.21,41,{"v":1.01404E-5,"d":"1.01E-05"},0.000573997,"GTEx/v8/Pancreas","+","Yes","EP_correlation_cell_type_oneway:IMR90:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T;rs10075801:5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs200800380",9]
["ENSG00000164399","IL3",5,131396222,131398897,1,"protein_coding",3562,"IL3",{"v":3.72135953228091e-09,"d":"3.72E-09"},-0.398764897,7,14.89,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Spleen:IMR90:Mesendoderm",0.00019,"rs10075801",9]
["ENSG00000164400","CSF2",5,131409483,131411859,1,"protein_coding",1437,"CSF2",0.803849286352491,-0.384982343,10,14.89,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:GM12878:IMR90:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;rs10075801:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T;rs10075801:rs200800380",9]
["ENSG00000072682","P4HA2",5,131527531,131631008,-1,"protein_coding",8974,"P4HA2",{"v":6.46128411074688e-05,"d":"6.46E-05"},-0.308598295,58,18.28,223,{"v":2.48276e-38,"d":"2.48E-38"},{"v":2.11549e-31,"d":"2.12E-31"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T;rs200800380;rs10075801:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T;rs10075801:rs200800380",9]
["ENSG00000131435","PDLIM4",5,131593364,131609147,1,"protein_coding",8572,"PDLIM4",0.924088701530717,-0.066167667,27,18.28,223,{"v":2.42795E-21,"d":"2.43E-21"},{"v":6.02052e-16,"d":"6.02E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T;rs200800380;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000197208","SLC22A4",5,131630136,131679899,1,"protein_coding",6583,"SLC22A4",{"v":4.64079476855844e-06,"d":"4.64E-06"},-0.51561879,90,13.88,223,{"v":2.7801e-09,"d":"2.78E-09"},{"v":6.7175e-07,"d":"6.72E-07"},"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T;rs200800380;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000197375","SLC22A5",5,131705444,131731306,1,"protein_coding",6584,"SLC22A5",{"v":4.90000271154311e-09,"d":"4.90E-09"},0.858089401,63,21.7,223,{"v":1.27641E-27,"d":"1.28E-27"},{"v":6.23252e-22,"d":"6.23E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380;rs10075801;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000197536","C5orf56",5,131746328,131811736,1,"protein_coding",441108,"C5orf56",0.107649237505837,"NA",18,9.904,131,{"v":9.70217e-11,"d":"9.70E-11"},{"v":3.3657e-48,"d":"3.37E-48"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex:Left_Ventricle:Liver:Psoas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T;rs200800380;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000125347","IRF1",5,131817301,131826490,-1,"protein_coding",3659,"IRF1",0.867788618113854,0.555445443,1,4.69,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Psoas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:5:131664516_TTATATA_T;rs200800380:rs10075801:rs200800380",9]
["ENSG00000113525","IL5",5,131877136,131892530,-1,"protein_coding",3567,"IL5",0.0283744149089649,-0.161789195,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000113522","RAD50",5,131891711,131980313,1,"protein_coding",10111,"RAD50",{"v":3.45027967852237e-15,"d":"3.45E-15"},-1.018272128,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000169194","IL13",5,131991955,131996802,1,"protein_coding",3596,"IL13",0.0257146912157871,0.123554035,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000113520","IL4",5,132009678,132018368,1,"protein_coding",3565,"IL4",0.168021415276942,-0.004195228,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000131437","KIF3A",5,132028320,132073330,-1,"protein_coding",11127,"KIF3A",0.992416127781631,-0.460356314,0,0,36,{"v":8.42388e-06,"d":"8.42E-06"},{"v":1.44548e-23,"d":"1.45E-23"},"GTEx/v8/Artery_Tibial","+","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801;5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000205089","CCNI2",5,132083137,132089856,1,"protein_coding",645121,"CCNI2",{"v":4.53255419093452e-05,"d":"4.53E-05"},0.828805181,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000164402","2008-09-01",5,132086509,132142933,-1,"protein_coding",23176,"2008-09-01",0.954285718069544,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000198944","SOWAHA",5,132149033,132152488,1,"protein_coding",134548,"SOWAHA","NA",0.065648167,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000164403","SHROOM1",5,132157833,132166590,-1,"protein_coding",134549,"SHROOM1",0.00959554880204162,-0.760290944,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs200800380:rs200800380:5:131664516_TTATATA_T;rs10075801:rs10075801",9]
["ENSG00000164404","GDF9",5,132196873,132202576,-1,"protein_coding",2661,"GDF9",{"v":1.19472233006091e-05,"d":"1.19E-05"},0.352487907,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000164405","UQCRQ",5,132202252,132203723,1,"protein_coding",27089,"UQCRQ",0.0919129783108912,-0.564493203,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000164406","LEAP2",5,132208014,132210738,1,"protein_coding",116842,"LEAP2",0.00789837798993102,1.43844583,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000072364","AFF4",5,132211071,132299326,-1,"protein_coding",27125,"AFF4",0.999997450786603,-1.861324311,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801:rs200800380",9]
["ENSG00000155329","ZCCHC10",5,132332677,132362296,-1,"protein_coding",54819,"ZCCHC10",0.16080191147859,-0.209780051,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878",{"v":1.3e-08,"d":"1.30E-08"},"rs10075801:5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801",9]
["ENSG00000170606","HSPA4",5,132387654,132442141,1,"protein_coding",3308,"HSPA4",0.999958225713848,-0.069630552,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878",{"v":1.3e-08,"d":"1.30E-08"},"5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs10075801",9]
["ENSG00000213585","VDAC1",5,133307606,133340824,-1,"protein_coding",7416,"VDAC1",0.975595138410154,-0.326089734,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801:5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs200800380",9]
["ENSG00000113558","SKP1",5,133484633,133512729,-1,"protein_coding",6500,"SKP1",0.224830619473668,2.132007545,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.7e-10,"d":"1.70E-10"},"rs10075801:5:131664516_TTATATA_T;rs200800380:5:131664516_TTATATA_T:5:131664516_TTATATA_T;rs10075801:rs200800380",9]
["ENSG00000082516","GEMIN5",5,154266976,154317769,-1,"protein_coding",25929,"GEMIN5",{"v":3.13420201203131E-14,"d":"3.13E-14"},-0.693060045,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7e-12,"d":"7.00E-12"},"rs4704728:rs6882345:rs4704835:5:156392653_CA_C",10]
["ENSG00000082515","MRPL22",5,154320630,154348971,1,"protein_coding",29093,"MRPL22",{"v":3.44167883429456e-07,"d":"3.44E-07"},0.276799402,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7e-12,"d":"7.00E-12"},"rs4704728:rs6882345:rs4704835:5:156392653_CA_C",10]
["ENSG00000170624","SGCD",5,155297354,156194799,1,"protein_coding",6444,"SGCD",0.00233910042363156,0.319696283,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7e-12,"d":"7.00E-12"},"rs4704728:rs6882345:rs4704835:5:156392653_CA_C:rs760614621",10]
["ENSG00000145850","TIMD4",5,156346293,156390266,-1,"protein_coding",91937,"TIMD4",{"v":4.33746964441321e-08,"d":"4.34E-08"},0.360934801,29,10.22,39,{"v":6.1249e-06,"d":"6.12E-06"},0.0123016,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops",{"v":7e-12,"d":"7.00E-12"},"rs4704728;rs6882345;rs4704835;5:156392653_CA_C;rs4704835:rs4704728",10]
["ENSG00000113249","HAVCR1",5,156456424,156486130,-1,"protein_coding",26762,"HAVCR1",0.00305433633416917,-0.160669209,55,9.969,131,{"v":2.75285E-18,"d":"2.75E-18"},{"v":5.93632e-22,"d":"5.94E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Coronary","+","Yes","Promoter_anchored_loops",{"v":7e-12,"d":"7.00E-12"},"rs4704835;rs4704728;rs6882345;rs4704728:rs4704835",10]
["ENSG00000135077","HAVCR2",5,156512843,156569880,-1,"protein_coding",84868,"HAVCR2",0.111384118892431,0.940999528,0,0,23,{"v":5.31832e-05,"d":"5.32E-05"},0.000319789,"GTEx/v8/Artery_Aorta","-","No","NA",{"v":7.5e-09,"d":"7.50E-09"},"rs4704835",10]
["ENSG00000113272","THG1L",5,157158205,157168456,1,"protein_coding",54974,"THG1L",{"v":3.48304059537209e-05,"d":"3.48E-05"},1.451409669,0,0,1,0.000192414,{"v":3.05013e-08,"d":"3.05E-08"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":1.2e-06,"d":"1.20E-06"},"rs4704835",10]
["ENSG00000079689","SCGN",6,25652464,25702011,1,"protein_coding",10590,"SCGN",0.0359460022848758,0.102935794,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-06,"d":"3.30E-06"},"rs147662640",11]
["ENSG00000124568","SLC17A1",6,25783125,25832287,-1,"protein_coding",6568,"SLC17A1",{"v":2.59261497697838e-10,"d":"2.59E-10"},-0.181263012,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":6e-08,"d":"6.00E-08"},"rs147662640:rs9257779",11]
["ENSG00000124564","SLC17A3",6,25833294,25882514,-1,"protein_coding",10786,"SLC17A3",{"v":9.88205561287661e-14,"d":"9.88E-14"},-0.246502705,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":6e-08,"d":"6.00E-08"},"rs9257779;rs147662640:rs147662640:rs9257779",11]
["ENSG00000112337","SLC17A2",6,25912982,25930946,-1,"protein_coding",10246,"SLC17A2",0.00466985446742192,-0.129201002,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640:rs9257779;rs147662640:rs9257779:rs567880264",11]
["ENSG00000112343","TRIM38",6,25963030,25987384,1,"protein_coding",10475,"TRIM38",{"v":4.75130205096512e-06,"d":"4.75E-06"},-0.220583262,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.2E-7,"d":"4.20E-07"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000124610","HIST1H1A",6,26017260,26018040,-1,"protein_coding",3024,"HIST1H1A",0.00353079926543669,-0.372206788,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000198366","HIST1H3A",6,26020718,26021186,1,"protein_coding",8350,"HIST1H3A",{"v":3.98008178767139e-05,"d":"3.98E-05"},-0.225706842,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000196176","HIST1H4A",6,26021907,26022278,1,"protein_coding",8359,"HIST1H4A",0.00228540295756206,0.434170117,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000124529","HIST1H4B",6,26027124,26027480,-1,"protein_coding",8366,"HIST1H4B",8.54182671998013E-3,0.166119276,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000124693","HIST1H3B",6,26031817,26032288,-1,"protein_coding",8358,"HIST1H3B",0.307282993148648,0.251696243,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000137259","HIST1H2AB",6,26033320,26033796,-1,"protein_coding",8335,"HIST1H2AB",0.00531944331445787,0.228134732,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000196226","HIST1H2BB",6,26043455,26043885,-1,"protein_coding",3018,"HIST1H2BB",0.130327871216174,0.288116693,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000196532","HIST1H3C",6,26045639,26046097,1,"protein_coding",8352,"HIST1H3C",0.215540519058334,-0.193878787,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000187837","HIST1H1C",6,26055968,26056699,-1,"protein_coding",3006,"HIST1H1C","NA",0.137228042,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000010704","HFE",6,26087509,26098571,1,"protein_coding",3077,"HFE",{"v":8.4969700310781e-07,"d":"8.50E-07"},0.210171656,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000197061","HIST1H4C",6,26104104,26104518,1,"protein_coding",8364,"HIST1H4C",{"v":8.85616839210981e-05,"d":"8.86E-05"},0.852191535,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000187475","HIST1H1T",6,26107640,26108364,-1,"protein_coding",3010,"HIST1H1T","NA",-0.068039131,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000197697","HIST1H2BE",6,26183958,26184454,1,"protein_coding",8344,"HIST1H2BE",0.000307871828087192,0.445738376,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000188987","HIST1H4D",6,26188938,26189304,-1,"protein_coding",8360,"HIST1H4D",0.00226430020608533,0.870145303,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000197409","HIST1H3D",6,26197068,26199521,-1,"protein_coding",8351,"HIST1H3D",0.011195071454157,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000196866","HIST1H2AD",6,26199079,26199471,-1,"protein_coding",3013,"HIST1H2AD",{"v":3.99677268819075e-05,"d":"4.00E-05"},0.28775859,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000197846","HIST1H2BF",6,26199748,26200942,1,"protein_coding",8343,"HIST1H2BF",0.000300020472922898,0.851062902,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000198518","HIST1H4E",6,26204858,26206266,1,"protein_coding",8367,"HIST1H4E",0.000642250549090646,1.835781936,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000187990","HIST1H2BG",6,26216428,26216872,-1,"protein_coding",8339,"HIST1H2BG",{"v":2.94452400546665E-6,"d":"2.94E-06"},0.025345178,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000168274","HIST1H2AE",6,26217165,26217711,1,"protein_coding",3012,"HIST1H2AE",0.62412365369502,-0.273878285,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000196966","HIST1H3E",6,26225383,26225844,1,"protein_coding",8353,"HIST1H3E",0.000813428842528686,-0.20979509,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000124575","HIST1H1D",6,26234440,26235216,-1,"protein_coding",3007,"HIST1H1D","NA",0.136123163,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000198327","HIST1H4F",6,26240561,26240976,1,"protein_coding",8361,"HIST1H4F",0.181985150966619,1.063119385,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-5,"d":"1.40E-05"},"rs147662640",11]
["ENSG00000124578","HIST1H4G",6,26246886,26247259,-1,"protein_coding",8369,"HIST1H4G",0.00262999657981332,-0.050940889,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-5,"d":"1.40E-05"},"rs147662640",11]
["ENSG00000256316","HIST1H3F",6,26250370,26250835,-1,"protein_coding",8968,"HIST1H3F",0.042215361750485,-0.181854433,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-5,"d":"1.40E-05"},"rs147662640",11]
["ENSG00000197459","HIST1H2BH",6,26251879,26252303,1,"protein_coding",8345,"HIST1H2BH",0.000295729876724394,-0.173874453,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-5,"d":"1.40E-05"},"rs147662640",11]
["ENSG00000256018","HIST1H3G",6,26271146,26271612,-1,"protein_coding",8355,"HIST1H3G",{"v":1.71005632806188e-05,"d":"1.71E-05"},0.234420172,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-5,"d":"1.40E-05"},"rs147662640",11]
["ENSG00000168242","HIST1H2BI",6,26273144,26273622,1,"protein_coding",8346,"HIST1H2BI",0.138012141980387,-0.249747536,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.4E-5,"d":"1.40E-05"},"rs147662640",11]
["ENSG00000158406","HIST1H4H",6,26281283,26285762,-1,"protein_coding",8365,"HIST1H4H",0.00879032933359599,1.05906941,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.1e-07,"d":"6.10E-07"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000186470","BTN3A2",6,26365387,26378546,1,"protein_coding",11118,"BTN3A2",0.000124518814289725,2.207914013,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000124508","BTN2A2",6,26383324,26395102,1,"protein_coding",10385,"BTN2A2",0.000150288420483044,1.015715449,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000026950","BTN3A1",6,26402465,26415444,1,"protein_coding",11119,"BTN3A1",{"v":8.65113669435817E-7,"d":"8.65E-07"},1.627912919,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000111801","BTN3A3",6,26440700,26453643,1,"protein_coding",10384,"BTN3A3",{"v":7.19024879190517e-10,"d":"7.19E-10"},1.090110123,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000112763","BTN2A1",6,26458150,26476849,1,"protein_coding",11120,"BTN2A1",{"v":1.07467588553941e-18,"d":"1.07E-18"},0.260570683,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000124557","BTN1A1",6,26501449,26510650,1,"protein_coding",696,"BTN1A1",{"v":1.14088369109076e-09,"d":"1.14E-09"},-0.32970456,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7E-5,"d":"1.70E-05"},"rs147662640",11]
["ENSG00000182952","HMGN4",6,26538633,26546482,1,"protein_coding",10473,"HMGN4",0.557082341510099,-0.351002587,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000146109","ABT1",6,26597180,26600278,1,"protein_coding",29777,"ABT1",0.0271055673799205,0.104221009,0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000181315","ZNF322",6,26636518,26659980,-1,"protein_coding",79692,"ZNF322","NA",-1.140467931,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":4.2E-7,"d":"4.20E-07"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000124635","HIST1H2BJ",6,27093676,27100541,-1,"protein_coding",8970,"HIST1H2BJ",0.47884211441258,0.308582046,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Bladder:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779",11]
["ENSG00000196787","HIST1H2AG",6,27100832,27103070,1,"protein_coding",8969,"HIST1H2AG",0.000610464103704842,-0.741637225,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Bladder:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779",11]
["ENSG00000197903","HIST1H2BK",6,27106073,27114619,-1,"protein_coding",85236,"HIST1H2BK",0.490754148427297,-0.043052263,0,0,32,{"v":9.90696e-05,"d":"9.91E-05"},0.000333743,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Bladder:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000198339","HIST1H4I",6,27107076,27108418,1,"protein_coding",8294,"HIST1H4I",0.446296012965993,-0.468005112,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Bladder:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779",11]
["ENSG00000184825","HIST1H2AH",6,27114861,27115317,1,"protein_coding",85235,"HIST1H2AH",{"v":6.2950794420684e-05,"d":"6.30E-05"},0.194919981,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Bladder:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779",11]
["ENSG00000112812","PRSS16",6,27215480,27224403,1,"protein_coding",10279,"PRSS16",{"v":2.23791834002529e-06,"d":"2.24E-06"},0.008848123,0,0,52,{"v":3.81686e-07,"d":"3.82E-07"},{"v":6.32593e-10,"d":"6.33E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000158553","POM121L2",6,27253682,27279949,-1,"protein_coding",94026,"POM121L2","NA",0.313408259,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779",11]
["ENSG00000124613","ZNF391",6,27342394,27371683,1,"protein_coding",346157,"ZNF391",{"v":9.25869403182407e-07,"d":"9.26E-07"},1.231716533,0,0,80,{"v":6.77474E-7,"d":"6.77E-07"},{"v":2.75877e-96,"d":"2.76E-96"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.5e-08,"d":"1.50E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs9257779:rs9257794",11]
["ENSG00000096654","ZNF184",6,27418522,27440897,-1,"protein_coding",7738,"ZNF184",0.133748635714874,-0.545662357,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640:rs9257779;rs147662640:rs9257779:rs567880264",11]
["ENSG00000185130","HIST1H2BL",6,27775257,27775709,-1,"protein_coding",8340,"HIST1H2BL",0.00286755404850941,-0.03011099,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000196747","HIST1H2AI",6,27775899,27776429,1,"protein_coding",8329,"HIST1H2AI",0.581587114173739,-0.058326504,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000203813","HIST1H3H",6,27777842,27778314,1,"protein_coding",8357,"HIST1H3H",0.02493915563981,-0.177817416,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000182611","HIST1H2AJ",6,27782112,27782607,-1,"protein_coding",8331,"HIST1H2AJ",0.19119768143705,0.615053632,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000196374","HIST1H2BM",6,27782822,27783267,1,"protein_coding",8342,"HIST1H2BM",0.00275346435077864,-0.27562,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000197238","HIST1H4J",6,27791884,27792257,1,"protein_coding",8363,"HIST1H4J",0.423753830207411,0.598449973,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000197914","HIST1H4K",6,27798952,27799305,-1,"protein_coding",8362,"HIST1H4K",0.429118935200097,0.387416315,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000184348","HIST1H2AK",6,27805658,27806117,-1,"protein_coding",8330,"HIST1H2AK",0.0684285015781424,-0.04124411,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000233822","HIST1H2BN",6,27806323,27823487,1,"protein_coding",8341,"HIST1H2BN",0.139774615254902,0.145508408,0,0,179,{"v":3.08881e-06,"d":"3.09E-06"},0.00215173,"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs9257779;rs147662640:rs9257779",11]
["ENSG00000198374","HIST1H2AL",6,27833034,27833606,1,"protein_coding",8332,"HIST1H2AL",0.0624869158210738,-0.360341181,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000184357","HIST1H1B",6,27834570,27835359,-1,"protein_coding",3009,"HIST1H1B",0.509138756022723,-0.08989506,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640:rs9257779;rs147662640",11]
["ENSG00000182572","HIST1H3I",6,27839623,27840099,-1,"protein_coding",8354,"HIST1H3I",0.360879945054601,-0.232438013,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000198558","HIST1H4L",6,27840926,27841289,-1,"protein_coding",8368,"HIST1H4L",0.191234624133278,0.426890108,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000197153","HIST1H3J",6,27858093,27860884,-1,"protein_coding",8356,"HIST1H3J",0.695883936820569,-0.189708056,1,4.095,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000233224","HIST1H2AM",6,27860477,27860963,-1,"protein_coding",8336,"HIST1H2AM",0.000856482029037302,-0.225135146,1,4.095,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000196331","HIST1H2BO",6,27861203,27861669,1,"protein_coding",8348,"HIST1H2BO",{"v":3.07277582735277E-5,"d":"3.07E-05"},-0.223062534,1,4.095,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000168131","OR2B2",6,27878963,27880174,-1,"protein_coding",81697,"OR2B2",{"v":6.86720334316105e-05,"d":"6.87E-05"},-0.212076212,5,23.2,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000124657","OR2B6",6,27925019,27925960,1,"protein_coding",26212,"OR2B6",0.0407309275321611,-0.098173144,1,2E-3,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-08,"d":"3.00E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs9257779:rs567880264",11]
["ENSG00000197279","ZNF165",6,28048753,28057341,1,"protein_coding",7718,"ZNF165",0.000563292029886091,0.227981468,5,5.177,306,{"v":1.60443E-6,"d":"1.60E-06"},{"v":1.94586E-12,"d":"1.95E-12"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-08,"d":"5.60E-08"},"rs147662640;rs9257779;rs147662640:rs9257779",11]
["ENSG00000196812","ZSCAN16",6,28092338,28097860,1,"protein_coding",80345,"ZSCAN16",{"v":2.67303498489914e-06,"d":"2.67E-06"},0.184187397,3,4.074,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000198315","ZKSCAN8",6,28109688,28127250,1,"protein_coding",7745,"ZKSCAN8",2.31594506551783E-4,-0.142528224,9,7.616,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.2E-7,"d":"4.20E-07"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000137185","ZSCAN9",6,28192664,28201260,1,"protein_coding",7746,"ZSCAN9",{"v":4.10248860506101e-08,"d":"4.10E-08"},0.461166178,5,7.251,280,0.000108097,{"v":1.5619e-05,"d":"1.56E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","-","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs9257779;rs147662640:rs9257779",11]
["ENSG00000187626","ZKSCAN4",6,28212401,28227011,-1,"protein_coding",387032,"ZKSCAN4",{"v":6.74288454800845e-05,"d":"6.74E-05"},0.661631344,3,5.18,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000189134","NKAPL",6,28227098,28228736,1,"protein_coding",222698,"NKAPL",0.000165621301014734,0.051342603,2,5.18,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000137338","PGBD1",6,28249314,28270326,1,"protein_coding",84547,"PGBD1",{"v":1.46735073363618E-5,"d":"1.47E-05"},-0.0800605,11,14.75,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-05,"d":"1.00E-05"},"rs147662640",11]
["ENSG00000235109","ZSCAN31",6,28292470,28324048,-1,"protein_coding",64288,"ZSCAN31",{"v":3.7712697083703e-09,"d":"3.77E-09"},1.107125092,13,13.57,241,{"v":1.12622E-10,"d":"1.13E-10"},{"v":4.37287e-25,"d":"4.37E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-08,"d":"3.00E-08"},"rs147662640;rs9257779",11]
["ENSG00000189298","ZKSCAN3",6,28317691,28336947,1,"protein_coding",80317,"ZKSCAN3",0.000122608322341288,-0.65244291,7,13.57,234,{"v":5.34891e-07,"d":"5.35E-07"},{"v":4.57962e-07,"d":"4.58E-07"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-08,"d":"3.00E-08"},"rs147662640;rs9257779",11]
["ENSG00000158691","ZSCAN12",6,28346732,28367511,-1,"protein_coding",9753,"ZSCAN12",{"v":1.43991732878074E-5,"d":"1.44E-05"},"NA",11,9.552,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-07,"d":"1.50E-07"},"rs147662640;rs147662640:rs9257779",11]
["ENSG00000187987","ZSCAN23",6,28399707,28411279,-1,"protein_coding",222696,"ZSCAN23",0.00270295085017911,0.070656525,3,2.102,363,{"v":5.88726e-14,"d":"5.89E-14"},{"v":8.30529e-55,"d":"8.31E-55"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs147662640;rs9257779;rs9257794;rs147662640:rs9257779",11]
["ENSG00000198704","GPX6",6,28471073,28495992,-1,"protein_coding",257202,"GPX6",{"v":3.13757952195529e-05,"d":"3.14E-05"},0.718702709,1,0.984,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640;rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000224586","GPX5",6,28493702,28502729,1,"protein_coding",2880,"GPX5",0.00888467745572368,0.354876486,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.2e-08,"d":"3.20E-08"},"rs147662640:rs9257779;rs147662640:rs567880264:rs9257779",11]
["ENSG00000232040","SCAND3",6,28539407,28583989,-1,"protein_coding",114821,"SCAND3",{"v":9.70724396864633e-09,"d":"9.71E-09"},-0.785031462,4,10.48,15,{"v":2.70076e-05,"d":"2.70E-05"},{"v":1.85651E-8,"d":"1.86E-08"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.6e-08,"d":"5.60E-08"},"rs147662640;rs9257779;rs147662640:rs9257779",11]
["ENSG00000204713","TRIM27",6,28870779,28891766,-1,"protein_coding",5987,"TRIM27",0.878751858118275,-0.142067713,15,18.69,4,{"v":9.05276e-05,"d":"9.05E-05"},{"v":9.5578e-15,"d":"9.56E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs9257779;rs147662640;rs147662640:rs147662640:rs9257779",11]
["ENSG00000204709","C6orf100",6,28911654,28912314,1,"protein_coding",729583,"C6orf100","NA","NA",8,3.641,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Trophoblast-like_Cell:hESC",{"v":3.9e-08,"d":"3.90E-08"},"rs9257779;rs147662640;rs147662640:rs147662640:rs9257779",11]
["ENSG00000197935","ZNF311",6,28962562,28973093,-1,"protein_coding",282890,"ZNF311",0.000129446471411909,0.377857886,9,11.6,4,{"v":7.83821e-05,"d":"7.84E-05"},{"v":1.05129e-10,"d":"1.05E-10"},"GTEx/v8/Artery_Tibial","+","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs9257779;rs147662640;rs147662640:rs9257779:rs147662640:rs567880264:rs9257794",11]
["ENSG00000204704","OR2W1",6,29011990,29013017,-1,"protein_coding",26692,"OR2W1",0.0865618905271982,0.531528388,7,6.576,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204703","OR2B3",6,29053985,29055090,-1,"protein_coding",442184,"OR2B3",1.3369321318042E-3,0.458839963,3,9.377,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3e-08,"d":"3.00E-08"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204702","OR2J1",6,29068386,29069658,1,"protein_coding",442185,"OR2J1",0.0174945019459341,"NA",1,0.549,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3e-08,"d":"3.00E-08"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204701","OR2J3",6,29079668,29080603,1,"protein_coding",442186,"OR2J3",0.0281435008681581,0.112859372,2,1.351,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3e-08,"d":"3.00E-08"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204700","OR2J2",6,29141311,29142351,1,"protein_coding",26707,"OR2J2",0.0107267189301636,0.271259236,3,5.147,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204695","OR14J1",6,29274403,29275519,1,"protein_coding",442191,"OR14J1",{"v":8.02406099709927e-08,"d":"8.02E-08"},1.335471591,4,10.49,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-08,"d":"3.00E-08"},"rs9257779;rs147662640;rs147662640:rs9257779:rs147662640",11]
["ENSG00000243729","OR5V1",6,29323007,29399744,-1,"protein_coding",81696,"OR5V1",0.00344261897900665,0.32363506,13,11.39,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs9257779;rs9257794;rs147662640;rs147662640:rs147662640",11]
["ENSG00000112462","OR12D3",6,29341200,29343068,-1,"protein_coding",81797,"OR12D3",{"v":1.34136303903671e-05,"d":"1.34E-05"},0.883548764,5,11.39,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs9257794;rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000168787","OR12D2",6,29364416,29365448,1,"protein_coding",26529,"OR12D2",0.601033125257784,0.457835329,3,6.779,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesendoderm:hESC",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204694","OR11A1",6,29393281,29424848,-1,"protein_coding",26531,"OR11A1",0.0434844025575059,1.230255274,4,3.951,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs147662640",11]
["ENSG00000206474","OR10C1",6,29407083,29408731,1,"protein_coding",442194,"OR10C1",0.227592079399406,0.363897038,3,1.81,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs147662640",11]
["ENSG00000204688","OR2H1",6,29424958,29432105,1,"protein_coding",26716,"OR2H1",0.0449040613109769,-0.358288136,4,3.951,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs147662640",11]
["ENSG00000204687","MAS1L",6,29454474,29455738,-1,"protein_coding",116511,"MAS1L",0.000466205666114264,0.689547747,5,8.385,0,"NA","NA","NA","NA","Yes","Aorta:Liver:Pancreas:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs9257779;rs147662640;rs147662640:rs9257779;rs147662640:rs9257779:rs9257794",11]
["ENSG00000213886","UBD",6,29523292,29527702,-1,"protein_coding",10537,"UBD",0.0798957514124674,0.401530797,4,14.02,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs9257779;rs147662640;rs147662640:rs9257779:rs147662640:rs567880264:rs9257794",11]
["ENSG00000204681","GABBR1",6,29523406,29601753,-1,"protein_coding",2550,"GABBR1",0.999969901472702,0.238892484,7,14.02,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.5e-07,"d":"1.50E-07"},"rs9257779;rs147662640;rs147662640:rs9257779",11]
["ENSG00000204657","OR2H2",6,29555683,29556745,1,"protein_coding",7932,"OR2H2",0.0899459247726437,0.69683603,2,2.181,282,{"v":1.16286e-09,"d":"1.16E-09"},{"v":1.93261E-11,"d":"1.93E-11"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs147662640;rs9257779;rs9257779:rs147662640:rs9257779;rs147662640:rs567880264:rs9257794",11]
["ENSG00000112514","CUTA",6,33384219,33386094,-1,"protein_coding",51596,"CUTA",{"v":1.14218167340545E-5,"d":"1.14E-05"},-0.619995669,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2E-5,"d":"1.20E-05"},"rs570810419",12]
["ENSG00000197283","SYNGAP1",6,33387847,33421466,1,"protein_coding",8831,"SYNGAP1",0.999998449747972,-1.109120657,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2E-5,"d":"1.20E-05"},"rs570810419",12]
["ENSG00000204188","GGNBP1",6,33551515,33556803,1,"protein_coding",449520,"GGNBP1","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":9.9e-06,"d":"9.90E-06"},"rs570810419",12]
["ENSG00000137288","UQCC2",6,33662070,33679504,-1,"protein_coding",84300,"UQCC2",0.0595477327271092,0.254207876,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2E-5,"d":"1.20E-05"},"rs570810419",12]
["ENSG00000269490","SBP1",6,33663196,33663474,-1,"protein_coding","NA","NA",0.00238547209488957,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000161896","IP6K3",6,33689444,33714762,-1,"protein_coding",117283,"IP6K3",0.0485338526527661,1.72324211,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000161904","LEMD2",6,33738979,33756913,-1,"protein_coding",221496,"LEMD2",0.302373361272148,0.392920076,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.9e-06,"d":"3.90E-06"},"rs570810419",12]
["ENSG00000124493","GRM4",6,33989628,34123399,-1,"protein_coding",2914,"GRM4",0.979350085369263,-0.635218754,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000137309","HMGA1",6,34204650,34214008,1,"protein_coding",3159,"HMGA1",0.724299774339856,-0.91011638,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.6e-06,"d":"8.60E-06"},"rs570810419",12]
["ENSG00000186577","C6orf1",6,34214157,34217247,-1,"protein_coding",221491,"C6orf1",0.29871864309512,-0.83430399,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":3.9e-06,"d":"3.90E-06"},"rs570810419",12]
["ENSG00000272325","NUDT3",6,34247456,34360451,-1,"protein_coding",11165,"NUDT3",0.876816622471426,0.134938478,163,15.89,147,{"v":4.46039e-07,"d":"4.46E-07"},1.88858E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000270800","RPS10-NUDT3",6,34256547,34393825,-1,"protein_coding",100529239,"RPS10-NUDT3","NA","NA",164,15.89,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000124614","RPS10",6,34385231,34393902,-1,"protein_coding",6204,"RPS10",0.946462997504496,0.20471765,3,8.962,154,{"v":1.13903e-11,"d":"1.14E-11"},{"v":2.19842e-09,"d":"2.20E-09"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000124507","PACSIN1",6,34433916,34503006,1,"protein_coding",29993,"PACSIN1",0.991339222233708,-1.593899928,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000124664","SPDEF",6,34505579,34524110,-1,"protein_coding",25803,"SPDEF",0.711825442176907,-0.407039982,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000196821","C6orf106",6,34555065,34664636,-1,"protein_coding",64771,"C6orf106",0.454029671085684,-1.135549043,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000124562","SNRPC",6,34725183,34741571,1,"protein_coding",6631,"SNRPC",0.727261777653869,-0.351120295,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.2E-5,"d":"1.20E-05"},"rs570810419",12]
["ENSG00000065060","UHRF1BP1",6,34759857,34850915,1,"protein_coding",54887,"UHRF1BP1",{"v":2.46541297366596e-07,"d":"2.47E-07"},-0.83035352,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000064995","TAF11",6,34845555,34855866,-1,"protein_coding",6882,"TAF11",0.875431936618392,-0.232568972,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000064999","ANKS1A",6,34857042,35059179,1,"protein_coding",23294,"ANKS1A",0.84685967793139,0.260682535,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000124678","TCP11",6,35085848,35116387,-1,"protein_coding",6954,"TCP11",{"v":4.00945484653237e-05,"d":"4.01E-05"},-0.41353592,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000146197","SCUBE3",6,35182190,35220856,1,"protein_coding",222663,"SCUBE3",0.9999837065276,-0.692415276,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000112033","PPARD",6,35310335,35395968,1,"protein_coding",5467,"PPARD",0.966868134632325,0.253948931,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":3.3e-08,"d":"3.30E-08"},"rs570810419",12]
["ENSG00000096060","FKBP5",6,35541362,35696360,-1,"protein_coding",2289,"FKBP5",0.498849476622916,-0.767039177,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.2E-5,"d":"1.20E-05"},"rs570810419",12]
["ENSG00000130363","RSPH3",6,159393903,159421219,-1,"protein_coding",83861,"RSPH3",0.00139623159251261,-0.228791289,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-9,"d":"1.80E-09"},"rs6925867",13]
["ENSG00000164694","FNDC1",6,159590429,159693141,1,"protein_coding",84624,"FNDC1",{"v":3.07460719768204e-07,"d":"3.07E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":5.2e-16,"d":"5.20E-16"},"rs6925867:rs9457827:rs9295128;rs117733303:rs117733303:rs9295128",13]
["ENSG00000112096","SOD2",6,160090089,160183561,-1,"protein_coding",6648,"SOD2",0.237154646295316,1.737932652,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-14,"d":"1.40E-14"},"rs6925867:rs9457827:rs117733303",13]
["ENSG00000146457","WTAP",6,160146617,160177351,1,"protein_coding",9589,"WTAP",0.995576734722068,1.745772008,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.3e-10,"d":"1.30E-10"},"rs6925867:rs9457827",13]
["ENSG00000120437","ACAT2",6,160181360,160200144,1,"protein_coding",39,"ACAT2",{"v":1.26453863126978e-05,"d":"1.26E-05"},0.731905322,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-14,"d":"1.40E-14"},"rs6925867:rs9457827:rs117733303",13]
["ENSG00000120438","TCP1",6,160199530,160210781,-1,"protein_coding",6950,"TCP1",0.989085751892209,0.157899873,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-16,"d":"5.20E-16"},"rs6925867:rs9295128;rs117733303:rs9457827:rs117733303:rs9295128",13]
["ENSG00000112110","MRPL18",6,160210844,160219468,1,"protein_coding",29074,"MRPL18",0.000794102804498299,1.581628342,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-16,"d":"5.20E-16"},"rs6925867:rs9295128;rs117733303:rs9457827:rs117733303:rs9295128",13]
["ENSG00000146453","PNLDC1",6,160221298,160241736,1,"protein_coding",154197,"PNLDC1",{"v":2.5447781123909e-08,"d":"2.54E-08"},0.054243557,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-16,"d":"5.20E-16"},"rs6925867:rs9295128;rs117733303:rs9457827:rs117733303:rs9295128",13]
["ENSG00000130368","MAS1",6,160327974,160329108,1,"protein_coding",4142,"MAS1",0.000870823408355688,-0.186942489,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.2e-17,"d":"7.20E-17"},"rs6925867:rs9457827:rs9295128;rs117733303:rs117733303:rs10455872",13]
["ENSG00000197081","IGF2R",6,160390131,160534539,1,"protein_coding",3482,"IGF2R",0.999999196216303,-0.312060143,27,8.367,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.2e-17,"d":"7.20E-17"},"rs6925867;rs9457827;rs6925867:rs9457827:rs117733303:rs9295128;rs117733303:rs9295128:rs10455872",13]
["ENSG00000175003","SLC22A1",6,160542821,160579750,1,"protein_coding",6580,"SLC22A1",{"v":1.23977716739769e-13,"d":"1.24E-13"},-0.158083671,2,5.481,25,{"v":5.41977e-14,"d":"5.42E-14"},{"v":3.85687e-11,"d":"3.86E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.5e-17,"d":"6.50E-17"},"rs6925867;rs9457827;rs9295128:rs9295128;rs117733303:rs6925867:rs117733303:rs9457827:rs16891156:rs10455872",13]
["ENSG00000112499","SLC22A2",6,160592093,160698670,-1,"protein_coding",6582,"SLC22A2",{"v":1.4191712191388E-9,"d":"1.42E-09"},0.905296138,3,2.542,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-16,"d":"5.20E-16"},"rs16891156;rs9295128;rs6925867:rs9295128;rs117733303:rs9295128:rs16891156",13]
["ENSG00000146477","SLC22A3",6,160769300,160876014,1,"protein_coding",6581,"SLC22A3",{"v":3.31638540911901E-5,"d":"3.32E-05"},0.310629054,2,0.392,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Psoas:Right_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-16,"d":"5.20E-16"},"rs9295128;rs117733303;rs6925867:rs9295128;rs117733303:rs16891156:rs9295128:rs9457827:rs117733303",13]
["ENSG00000198670","LPA",6,160952515,161087407,-1,"protein_coding",4018,"LPA",{"v":2.4422277924849E-32,"d":"2.44E-32"},0.042144435,5,5.891,5,{"v":5.73213e-08,"d":"5.73E-08"},1.04571E-4,"GTEx/v8/Liver","-","No","NA",{"v":6.5e-17,"d":"6.50E-17"},"rs10455872;rs56393506;rs9295128;rs117733303",13]
["ENSG00000122194","PLG",6,161123270,161174347,1,"protein_coding",5340,"PLG",0.00243511733948206,0.479258267,1,0.699,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm",{"v":3.8E-13,"d":"3.80E-13"},"rs10455872;rs9295128;rs117733303:rs76483627",13]
["ENSG00000085511","MAP3K4",6,161412759,161538417,1,"protein_coding",4216,"MAP3K4",0.999991910638856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":9.8e-09,"d":"9.80E-09"},"rs76483627",13]
["ENSG00000026652","AGPAT4",6,161551011,161695093,-1,"protein_coding",56895,"AGPAT4",0.674499951839515,0.748253089,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":9.4e-12,"d":"9.40E-12"},"rs76483627:rs10455872",13]
["ENSG00000185345","PARK2",6,161768452,163148803,-1,"protein_coding",5071,"PARK2",0.0218088318211922,0.549835313,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-17,"d":"6.50E-17"},"rs9295128:rs9295128;rs117733303:rs76483627:rs6925867:rs117733303:rs10455872",13]
["ENSG00000112530","PACRG",6,163148164,163736524,1,"protein_coding",135138,"PACRG",0.000104676937493315,0.454746473,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-17,"d":"6.50E-17"},"rs9295128:rs9295128;rs117733303:rs76483627:rs6925867:rs117733303:rs10455872",13]
["ENSG00000225683","AL078585.1",6,163586446,163612840,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.4e-12,"d":"9.40E-12"},"rs10455872:rs76483627",13]
["ENSG00000112531","QKI",6,163835032,163999628,1,"protein_coding",9444,"QKI",0.963163356453829,-0.183477081,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-17,"d":"6.50E-17"},"rs10455872:rs76483627",13]
["ENSG00000153790","C7orf31",7,25174316,25219975,-1,"protein_coding",136895,"C7orf31",{"v":7.44109236489478e-08,"d":"7.44E-08"},0.0581809,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.9e-07,"d":"2.90E-07"},"7:25942812_ACT_A",14]
["ENSG00000105954","NPVF",7,25264189,25268105,-1,"protein_coding",64111,"NPVF",2.64028304563325E-3,0.806254638,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000050344","NFE2L3",7,26191860,26226745,1,"protein_coding",9603,"NFE2L3",{"v":1.09962052794343E-7,"d":"1.10E-07"},0.033069722,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000122566","HNRNPA2B1",7,26229547,26241149,-1,"protein_coding",3181,"HNRNPA2B1",0.970043353092889,-1.698304487,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":1E-10,"d":"1.00E-10"},"rs4000713;7:25942812_ACT_A:7:25942812_ACT_A:rs4000713",14]
["ENSG00000122565","CBX3",7,26240782,26252976,1,"protein_coding",11335,"CBX3",0.633200403003169,0.096810086,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":1E-10,"d":"1.00E-10"},"rs4000713;7:25942812_ACT_A:7:25942812_ACT_A:rs4000713",14]
["ENSG00000086300","SNX10",7,26331541,26413949,1,"protein_coding",29887,"SNX10",0.00585750531238308,-0.279271767,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000122548","KIAA0087",7,26572740,26578407,-1,"protein_coding",9808,"KIAA0087","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000222004","C7orf71",7,26677490,26686889,1,"protein_coding",285941,"C7orf71","NA",-0.749780562,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000005020","SKAP2",7,26706681,27034858,-1,"protein_coding",8935,"SKAP2",0.909797277702382,-0.604966529,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000105991","HOXA1",7,27132612,27135615,-1,"protein_coding",3198,"HOXA1",0.0849873631655924,-0.680056534,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000105996","HOXA2",7,27139721,27142430,-1,"protein_coding",3199,"HOXA2",0.278337993967382,-0.425114196,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000105997","HOXA3",7,27145803,27192200,-1,"protein_coding",3200,"HOXA3",0.931754220622883,-0.602347946,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000197576","HOXA4",7,27168126,27170418,-1,"protein_coding",3201,"HOXA4",0.00942667003682843,0.361771686,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000106004","HOXA5",7,27180671,27183287,-1,"protein_coding",3202,"HOXA5",0.79621299361995,0.098403071,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000106006","HOXA6",7,27185015,27190222,-1,"protein_coding",3203,"HOXA6",{"v":1.80043020270311E-5,"d":"1.80E-05"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000122592","HOXA7",7,27193335,27197555,-1,"protein_coding",3204,"HOXA7",0.00316907031376716,-0.435656686,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000078399","HOXA9",7,27202054,27210117,-1,"protein_coding",3205,"HOXA9",1.00012594431347E-4,-0.353761021,0,0,0,"NA","NA","NA","NA","Yes","Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000257184","RP1-170O19.20",7,27203154,27219632,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000253293","HOXA10",7,27210210,27219880,-1,"protein_coding",3206,"HOXA10",0.678435260569461,-0.87103063,0,0,0,"NA","NA","NA","NA","Yes","Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000005073","HOXA11",7,27221129,27224842,-1,"protein_coding",3207,"HOXA11",0.863825169181447,0.401702198,0,0,0,"NA","NA","NA","NA","Yes","Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000106031","HOXA13",7,27233122,27239725,-1,"protein_coding",3209,"HOXA13","NA",-0.418411158,0,0,0,"NA","NA","NA","NA","Yes","Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000106038","EVX1",7,27282164,27290112,1,"protein_coding",2128,"EVX1",{"v":2.93029181691565e-05,"d":"2.93E-05"},-0.887444348,0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000106052","TAX1BP1",7,27778950,27884183,1,"protein_coding",8887,"TAX1BP1",{"v":2.99233082871036e-06,"d":"2.99E-06"},0.359414966,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm:Trophoblast-like_Cell",{"v":1E-10,"d":"1.00E-10"},"7:25942812_ACT_A:rs4000713",14]
["ENSG00000153814","JAZF1",7,27870192,28220362,-1,"protein_coding",221895,"JAZF1",0.958302381623798,-0.943258499,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.9e-07,"d":"2.90E-07"},"7:25942812_ACT_A",14]
["ENSG00000136271","DDX56",7,44605016,44614650,-1,"protein_coding",54606,"DDX56",{"v":3.51574131414912e-06,"d":"3.52E-06"},-0.604939687,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.7E-7,"d":"3.70E-07"},"rs73109460",15]
["ENSG00000158604","TMED4",7,44617493,44621886,-1,"protein_coding",222068,"TMED4",0.292927703052725,0.480384772,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.7E-7,"d":"3.70E-07"},"rs73109460",15]
["ENSG00000105953","OGDH",7,44646171,44748665,1,"protein_coding",4967,"OGDH",0.993695121200126,-0.070196077,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs73109460",15]
["ENSG00000122515","ZMIZ2",7,44788180,44809477,1,"protein_coding",83637,"ZMIZ2",0.999620382312933,0.41682603,17,8.079,19,{"v":3.30135e-13,"d":"3.30E-13"},{"v":8.21167E-9,"d":"8.21E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","+","No","NA",{"v":1.9e-08,"d":"1.90E-08"},"rs73109460",15]
["ENSG00000196262","PPIA",7,44836279,44864163,1,"protein_coding",5478,"PPIA",0.808049495342876,0.430904546,0,0,12,{"v":1.56786e-05,"d":"1.57E-05"},{"v":2.29167E-5,"d":"2.29E-05"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs73109460",15]
["ENSG00000146676","PURB",7,44915896,44924960,-1,"protein_coding",5814,"PURB",0.605935032790202,-2.57194086,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs73109460",15]
["ENSG00000136270","TBRG4",7,45139699,45151646,-1,"protein_coding",9238,"TBRG4",0.780939582899283,-0.259398376,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs73109460",15]
["ENSG00000183166","CALN1",7,71244476,71912136,-1,"protein_coding",83698,"CALN1",0.153650290078419,1.041424886,2,3.669,0,"NA","NA","NA","NA","Yes","hESC",{"v":7.3E-7,"d":"7.30E-07"},"rs71553242",16]
["ENSG00000196313","POM121",7,72349936,72421979,1,"protein_coding",9883,"POM121","NA",-1.370618997,1,0.733,167,{"v":8.97114e-08,"d":"8.97E-08"},{"v":1.50688E-66,"d":"1.51E-66"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":4.8e-46,"d":"4.80E-46"},"rs34821369;rs71553242;rs4717763;rs111432585;rs42238;rs138574868;rs62466318;rs42122;7:73042302_GCTTT_G;rs799157;rs111432585:rs62466318;rs42238:7:73042302_GCTTT_G;rs42122:rs7799778:rs62466318:rs42122:rs4717763:rs35489648:rs42238:rs34821369:7:72840443_CT_C:rs62466318;rs138574868:7:73042302_GCTTT_G:rs799157",16]
["ENSG00000155428","TRIM74",7,72430016,72439997,-1,"protein_coding",378108,"TRIM74",0.780333820359187,-0.947438302,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.3e-38,"d":"4.30E-38"},"7:73042302_GCTTT_G;rs42122:rs35489648:rs111432585:rs62466318;rs138574868",16]
["ENSG00000130305","NSUN5",7,72716514,72722864,-1,"protein_coding",55695,"NSUN5",{"v":1.45415268581091e-06,"d":"1.45E-06"},-0.276519006,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4e-44,"d":"4.00E-44"},"rs111432585:7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G;rs42122:rs62466318;rs138574868;rs42238:rs145099458:rs12531884:rs7799778:rs138574868:rs62466318;rs138574868:7:73042302_GCTTT_G:rs799157:7:72840443_CT_C:rs42122:rs35489648:rs62466318",16]
["ENSG00000146755","TRIM50",7,72726535,72742085,-1,"protein_coding",135892,"TRIM50",{"v":2.72561665019464E-6,"d":"2.73E-06"},-0.790238603,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2e-42,"d":"2.00E-42"},"rs34821369;rs71553242:rs42122:rs111432585:rs4717763:rs35489648:rs42238:rs34821369:7:72840443_CT_C:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G;rs35489648:rs62466318;rs138574868;rs42238:rs145099458:rs12531884:rs62466318;rs138574868:rs138574868:rs7799778:rs62466318",16]
["ENSG00000077800","FKBP6",7,72742167,72772634,1,"protein_coding",8468,"FKBP6",0.13060063873413,-0.33452228,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2e-42,"d":"2.00E-42"},"rs34821369;rs71553242:rs42122:rs111432585:rs4717763:rs35489648:rs42238:rs34821369:7:72840443_CT_C:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G;rs35489648:rs62466318;rs138574868;rs42238:rs145099458:rs12531884:rs62466318;rs138574868:rs138574868:rs7799778:rs62466318",16]
["ENSG00000188763","FZD9",7,72848109,72850450,1,"protein_coding",8326,"FZD9","NA","NA",21,12.41,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2e-42,"d":"2.00E-42"},"rs34821369;rs42122;7:72840443_CT_C;rs111432585;7:73042302_GCTTT_G;rs35489648;rs62466318;rs138574868;rs42238;rs145099458;rs71553242:rs42122:rs111432585:rs12531884:7:73042302_GCTTT_G;rs42122:rs62466318;rs42238:rs138574868:rs7799778:rs62466318",16]
["ENSG00000009954","BAZ1B",7,72854728,72936608,-1,"protein_coding",9031,"BAZ1B",0.999999562861573,-1.106984422,109,15.44,109,{"v":5.47336e-06,"d":"5.47E-06"},0.00482055,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-44,"d":"4.00E-44"},"rs111432585;7:73042302_GCTTT_G;rs35489648;rs42122;rs62466318;rs138574868;rs42238;rs145099458;rs12531884;rs7799778;rs138574868:7:73042302_GCTTT_G;rs42122:rs111432585:rs12531884:rs62466318;rs138574868:rs62466318:7:73042302_GCTTT_G;rs35489648:rs62466318;rs42238:rs145099458:rs7799778:7:73042302_GCTTT_G:rs799157:rs34821369;7:73097835_AG_A:rs35459363:7:72840443_CT_C:rs42122:rs35489648",16]
["ENSG00000106635","BCL7B",7,72950686,72972332,-1,"protein_coding",9275,"BCL7B",0.706637383924404,-0.386261382,55,18.49,190,{"v":2.43791E-17,"d":"2.44E-17"},{"v":3.40292E-13,"d":"3.40E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":9.7e-46,"d":"9.70E-46"},"rs111432585;rs12531884;rs138574868;7:73042302_GCTTT_G;rs42122;rs62466318;rs35489648;rs42238;rs34821369;rs71553242;rs111432585:rs62466318;rs42238:7:73042302_GCTTT_G;rs42122:rs35459363:rs34821369",16]
["ENSG00000106638","TBL2",7,72983262,72993121,-1,"protein_coding",26608,"TBL2",0.00437650656905421,8.921304858,41,10.3,57,{"v":1.05731e-06,"d":"1.06E-06"},{"v":4.93874e-46,"d":"4.94E-46"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":3.6e-44,"d":"3.60E-44"},"rs138574868;rs12531884;7:73042302_GCTTT_G;rs42122;rs62466318;rs111432585;rs34821369;7:73097835_AG_A;rs71553242;rs35489648;rs35459363;rs7799778;rs4717763;rs799161:rs144479473:rs10245965:rs799157:rs34821369;7:73097835_AG_A:rs35459363",16]
["ENSG00000009950","MLXIPL",7,73007524,73038873,-1,"protein_coding",51085,"MLXIPL",0.676823094036297,0.477223974,99,19.09,264,{"v":5.28937e-28,"d":"5.29E-28"},{"v":1.10979e-22,"d":"1.11E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex",{"v":4.8e-46,"d":"4.80E-46"},"rs111432585;rs62466318;rs138574868;rs35489648;7:73042302_GCTTT_G;rs42122;rs145099458;rs799157;7:73029139_CT_C;7:73034907_GA_G;rs35340690;7:73045341_CT_C;rs6975732;7:73047677_GT_G;rs34821369;rs71553242;rs4717763;rs42238;rs12531884;7:73097835_AG_A;rs799161;rs7799778;rs42122:7:73042302_GCTTT_G:rs111432585:rs145099458:rs62466318;rs138574868:rs35459363:rs799157:rs34821369",16]
["ENSG00000176428","VPS37D",7,73082155,73086442,1,"protein_coding",155382,"VPS37D",0.656347210550458,"NA",4,13.47,137,{"v":2.29153E-10,"d":"2.29E-10"},{"v":1.34286e-08,"d":"1.34E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":4.8e-46,"d":"4.80E-46"},"rs799157;rs34821369;7:73097835_AG_A;rs35459363;rs111432585;rs62466318;rs138574868;7:73042302_GCTTT_G;rs35340690;rs799161;rs42238;rs6975732;rs111432585:rs138574868:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs62466318;rs138574868:rs35489648:rs145099458:rs62466318;rs42238:rs799157:7:73034907_GA_G:rs62466318;7:73042302_GCTTT_G:rs35459363",16]
["ENSG00000176410","DNAJC30",7,73095299,73097783,-1,"protein_coding",84277,"DNAJC30",0.00479827795416004,0.303307808,10,13.47,9,{"v":1.57262e-08,"d":"1.57E-08"},{"v":1.33893E-9,"d":"1.34E-09"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops",{"v":7.9e-13,"d":"7.90E-13"},"rs34821369;7:73097835_AG_A;rs35459363;rs71553242",16]
["ENSG00000071462","WBSCR22",7,73097355,73119491,1,"protein_coding",114049,"WBSCR22",0.52115193984232,"NA",13,10.38,114,{"v":6.42965e-08,"d":"6.43E-08"},{"v":1.94637E-7,"d":"1.95E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops",{"v":6.2e-14,"d":"6.20E-14"},"rs35459363;7:73097835_AG_A;rs34821369;rs111432585;rs71553242",16]
["ENSG00000106089","STX1A",7,73113536,73134002,-1,"protein_coding",6804,"STX1A",0.910475757164848,-0.07051921,6,10.38,1,0.000203054,{"v":1.22792E-16,"d":"1.23E-16"},"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":4e-44,"d":"4.00E-44"},"rs35459363;rs34821369;7:73097835_AG_A;rs799161;rs62466318;rs138574868:rs111432585:7:73042302_GCTTT_G:rs799157",16]
["ENSG00000106077","ABHD11",7,73150424,73153197,-1,"protein_coding",83451,"ABHD11",{"v":9.03291221619057e-06,"d":"9.03E-06"},0.148517676,0,0,8,{"v":1.17311E-5,"d":"1.17E-05"},{"v":1.50054e-27,"d":"1.50E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":1.1E-45,"d":"1.10E-45"},"rs7799778;rs35459363;7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs111432585:rs145099458:rs62466318;rs138574868:rs35489648:7:73034907_GA_G:rs62466318",16]
["ENSG00000165215","CLDN3",7,73183328,73184600,-1,"protein_coding",1365,"CLDN3",0.678537320145956,-0.798792708,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":1.1E-45,"d":"1.10E-45"},"rs62466318;rs138574868",16]
["ENSG00000165171","WBSCR27",7,73248920,73256865,-1,"protein_coding",155368,"WBSCR27",0.0679116625114122,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.6e-44,"d":"3.60E-44"},"rs111432585:rs138574868:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs62466318;rs138574868:rs35489648",16]
["ENSG00000175877","WBSCR28",7,73275489,73280223,1,"protein_coding",135886,"WBSCR28",{"v":1.58800503099146E-6,"d":"1.59E-06"},0.424364093,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2e-42,"d":"2.00E-42"},"rs111432585:rs62466318;rs138574868;rs42238:7:73042302_GCTTT_G;rs42122:rs799157:rs34821369;7:73097835_AG_A:rs35459363",16]
["ENSG00000106683","LIMK1",7,73497263,73536855,1,"protein_coding",3984,"LIMK1",0.990896287164463,-0.781218183,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4e-44,"d":"4.00E-44"},"rs111432585:7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G;rs42122:rs62466318;rs138574868;rs42238:rs145099458:rs62466318;rs138574868:7:73042302_GCTTT_G:rs799157:rs34821369;7:73097835_AG_A:rs35459363",16]
["ENSG00000106682","EIF4H",7,73588575,73611431,1,"protein_coding",7458,"EIF4H",0.922544880243499,-1.500430355,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":7.6e-44,"d":"7.60E-44"},"7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs111432585:rs145099458:rs62466318;rs138574868:rs62466318;rs138574868;rs42238",16]
["ENSG00000086730","LAT2",7,73613982,73644161,1,"protein_coding",7462,"LAT2",0.000691063098880473,-0.479096813,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-42,"d":"2.20E-42"},"rs111432585:rs35340690:rs35340690;rs6975732:7:73042302_GCTTT_G:rs62466318:rs6975732:rs799161",16]
["ENSG00000049541","RFC2",7,73645829,73668774,-1,"protein_coding",5982,"RFC2",{"v":4.04212746398499e-05,"d":"4.04E-05"},-0.396975582,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2e-42,"d":"2.00E-42"},"rs111432585:7:73042302_GCTTT_G;rs42122:rs62466318;rs138574868;rs42238:rs799157:rs34821369;7:73097835_AG_A:rs35459363",16]
["ENSG00000106665","CLIP2",7,73703805,73820273,1,"protein_coding",7461,"CLIP2",0.999881647285659,0.2522342,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4e-44,"d":"4.00E-44"},"rs111432585:7:73042302_GCTTT_G;rs42122:rs62466318;rs138574868;rs42238:rs62466318;rs138574868:7:73042302_GCTTT_G:rs799157:rs34821369;7:73097835_AG_A:rs35459363",16]
["ENSG00000147324","MFHAS1",8,8640864,8751155,-1,"protein_coding",9258,"MFHAS1",{"v":2.22820045783843E-5,"d":"2.23E-05"},0.9551839,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesendoderm:Trophoblast-like_Cell",{"v":1.1e-15,"d":"1.10E-15"},"rs9987289;rs7357361:rs7357361:rs9987289:rs34290760:rs9987289;rs7357361;rs7008413",17]
["ENSG00000104626","ERI1",8,8859657,8974256,1,"protein_coding",90459,"ERI1",0.000454685197816091,0.949360106,0,0,25,{"v":1.7192E-6,"d":"1.72E-06"},{"v":1.58151e-06,"d":"1.58E-06"},"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-15,"d":"1.10E-15"},"rs9987289;rs7357361;rs7008413;rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7008413:rs7357361:rs7357361;rs7008413:rs7008413",17]
["ENSG00000173281","PPP1R3B",8,8993765,9009084,-1,"protein_coding",79660,"PPP1R3B",0.0229191412335762,3.70852971,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.1e-15,"d":"1.10E-15"},"rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7357361;rs7008413",17]
["ENSG00000253426","RP11-10A14.4",8,9009252,9025646,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.1e-15,"d":"1.10E-15"},"rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7357361;rs7008413",17]
["ENSG00000173273","TNKS",8,9413424,9639856,1,"protein_coding",8658,"TNKS",0.777115954184058,1.637267498,0,0,13,{"v":7.43105e-08,"d":"7.43E-08"},0.00127623,"GTEx/v8/Liver","+","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.1e-15,"d":"1.10E-15"},"rs9987289;rs7357361;rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7008413:rs7357361:rs7357361;rs7008413:rs7008413",17]
["ENSG00000171044","XKR6",8,10753555,11058875,-1,"protein_coding",286046,"XKR6",0.956776701241562,0.199430911,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.1e-15,"d":"1.10E-15"},"rs9987289:rs9987289;rs7357361:rs34290760:rs9987289;rs7357361;rs7008413",17]
["ENSG00000156006","NAT2",8,18248755,18258728,1,"protein_coding",10,"NAT2",0.0226078662097717,0.267314509,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.6E-9,"d":"3.60E-09"},"rs34669405:rs76722925:rs7001307:rs13273454",18]
["ENSG00000156011","PSD3",8,18384811,18942240,-1,"protein_coding",23362,"PSD3",0.851705649436322,1.354305318,0,0,0,"NA","NA","NA","NA","Yes","Aorta",{"v":1.4e-09,"d":"1.40E-09"},"rs7819706;rs76722925:rs34669405:rs76722925",18]
["ENSG00000104611","SH2D4A",8,19171128,19253729,1,"protein_coding",63898,"SH2D4A",{"v":1.53114480649588e-18,"d":"1.53E-18"},-0.083318155,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs7819706;rs76722925:rs7819706:rs15285:rs76722925:rs34669405:rs7001307:rs13273454",18]
["ENSG00000147408","CSGALNACT1",8,19261672,19615540,-1,"protein_coding",55790,"CSGALNACT1",{"v":6.87751081149391e-05,"d":"6.88E-05"},0.406270981,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs7819706;rs76722925:rs7819706:rs15285:rs76722925",18]
["ENSG00000104613","INTS10",8,19674651,19709594,1,"protein_coding",55174,"INTS10",0.984216594645776,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.9e-10,"d":"2.90E-10"},"rs7819706;rs76722925:rs7819706:rs15285:rs76722925:rs34669405:rs7001307:rs13273454",18]
["ENSG00000175445","LPL",8,19759228,19824769,1,"protein_coding",4023,"LPL",{"v":3.33727737763241e-06,"d":"3.34E-06"},1.047176611,43,50,87,{"v":4.28361e-08,"d":"4.28E-08"},1.73182E-4,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-10,"d":"2.90E-10"},"rs76722925;rs15285;rs7819706;rs34669405:rs76722925:rs7819706;rs76722925:rs7819706:rs15285:rs7001307:rs13273454",18]
["ENSG00000036565","SLC18A1",8,20002366,20040717,-1,"protein_coding",6570,"SLC18A1",{"v":1.8888318573672e-14,"d":"1.89E-14"},0.247527783,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Mesenchymal_Stem_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs76722925:rs7819706;rs76722925:rs7819706:rs15285",18]
["ENSG00000147416","ATP6V1B2",8,20054878,20084330,1,"protein_coding",526,"ATP6V1B2",0.991448562707497,-0.741850309,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs7819706;rs76722925:rs7819706:rs15285:rs76722925",18]
["ENSG00000189376","C8orf76",8,124232196,124253638,-1,"protein_coding",84933,"C8orf76",{"v":1.71944218858493e-05,"d":"1.72E-05"},-0.020072916,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.9E-28,"d":"1.90E-28"},"rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T",19]
["ENSG00000259305","ZHX1-C8ORF76",8,124238431,124279627,-1,"protein_coding",100533106,"ZHX1-C8ORF76",0.00105203127523669,-0.36802306,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.9E-28,"d":"1.90E-28"},"rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T",19]
["ENSG00000170881","RNF139",8,125486979,125500155,1,"protein_coding",11236,"RNF139",0.0608738334958745,-0.469220523,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.9E-28,"d":"1.90E-28"},"rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T",19]
["ENSG00000147687","TATDN1",8,125500726,125551699,-1,"protein_coding",83940,"TATDN1",{"v":1.72640600686597e-08,"d":"1.73E-08"},0.357863168,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-95,"d":"3.20E-95"},"rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891:rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T",19]
["ENSG00000147684","NDUFB9",8,125551344,125580751,1,"protein_coding",4715,"NDUFB9",0.0428894468164687,-0.016587227,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-95,"d":"3.20E-95"},"rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891:rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T",19]
["ENSG00000180938","ZNF572",8,125985540,125991631,1,"protein_coding",137209,"ZNF572",0.000651450621070101,-0.137914163,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":3.2e-95,"d":"3.20E-95"},"rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891:rs7012891",19]
["ENSG00000104549","SQLE",8,126010739,126034525,1,"protein_coding",6713,"SQLE",0.91297067975512,1.171693492,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-95,"d":"3.20E-95"},"rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T:rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891",19]
["ENSG00000164961","KIAA0196",8,126036502,126104082,-1,"protein_coding",9897,"KIAA0196",{"v":4.81024990398197e-13,"d":"4.81E-13"},-0.762157486,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-95,"d":"3.20E-95"},"rs2385114:rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891:rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T:rs72647336:rs2980874",19]
["ENSG00000156831","NSMCE2",8,126103921,126379362,1,"protein_coding",286053,"NSMCE2",0.0724507212755206,-0.471934498,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-95,"d":"3.20E-95"},"rs2385114:rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891:rs7012891:rs4360309:rs4419828:rs1809167:8:126531510_TACAC_T:rs72647336:rs2980874",19]
["ENSG00000173334","TRIB1",8,126442563,126450647,1,"protein_coding",10221,"TRIB1",0.606587656595858,-0.456914247,29,17.16,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":1e-28,"d":"1.00E-28"},"rs2980874;rs2385112;rs72647336;rs2385114;rs17405319;rs2980877;rs2980883;rs4871598;rs62521037;rs12674939;rs16900644;rs7012891:rs4360309:rs4419828:rs1809167:rs2385114",19]
["ENSG00000136997","MYC",8,128747680,128753674,1,"protein_coding",4609,"MYC","NA",-0.253124713,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.2e-95,"d":"3.20E-95"},"rs112875651;rs2954021;rs201123548:rs33924196;rs2980884;rs6988140:rs6988140:rs201123548:rs33924196;8:126492843_GT_G;rs6988140:rs33924196;8:126492843_GT_G:rs35309034;rs12674939;rs16900644:rs2954021:rs72655677:rs33924196:rs112875651;rs2954021:rs58253018:rs113334082:rs33924196;rs2980884:rs16900644:8:126492843_GT_G:rs35309034:rs35309034;rs16900644:rs574633917:8:126504383_CCACCAT_C:rs199591805:rs112875651:rs11420988:8:126511216_GA_G:8:126511216_GA_G;rs7012891:rs7012891",19]
["ENSG00000165029","ABCA1",9,107543283,107690518,-1,"protein_coding",19,"ABCA1",0.00165880319635912,0.082774215,6,15.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.7e-09,"d":"1.70E-09"},"rs1800978",20]
["ENSG00000070214","SLC44A1",9,108006903,108201452,1,"protein_coding",23446,"SLC44A1",0.999253571367297,-0.569151,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7e-09,"d":"1.70E-09"},"rs1800978",20]
["ENSG00000106701","FSD1L",9,108210077,108314714,1,"protein_coding",83856,"FSD1L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-09,"d":"1.70E-09"},"rs1800978",20]
["ENSG00000186051","TAL2",9,108424738,108425367,1,"protein_coding",6887,"TAL2",0.488535069507167,0.093363904,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.7e-09,"d":"1.70E-09"},"rs1800978",20]
["ENSG00000067057","PFKP",10,3108525,3179904,1,"protein_coding",5214,"PFKP",{"v":7.08342752970718E-15,"d":"7.08E-15"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.3e-08,"d":"2.30E-08"},"10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A",21]
["ENSG00000165568","AKR1E2",10,4828821,4890254,1,"protein_coding",83592,"AKR1E2",{"v":6.35197354907988e-06,"d":"6.35E-06"},1.491626915,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-08,"d":"2.30E-08"},"10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A",21]
["ENSG00000187134","AKR1C1",10,4934796,5025475,1,"protein_coding",1645,"AKR1C1",{"v":8.39898077933769e-06,"d":"8.40E-06"},5.07378856,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.4e-10,"d":"3.40E-10"},"10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A;rs56068105:rs7084630:rs56068105:10:5262963_AAC_A",21]
["ENSG00000151632","AKR1C2",10,5029967,5060223,-1,"protein_coding",1646,"AKR1C2",4.10317193583082E-3,2.217081159,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-10,"d":"3.40E-10"},"10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A;rs56068105:rs7084630:rs56068105:10:5262963_AAC_A",21]
["ENSG00000196139","AKR1C3",10,5077546,5149878,1,"protein_coding",8644,"AKR1C3",{"v":1.07139398635711e-11,"d":"1.07E-11"},0.642111095,54,6.566,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-10,"d":"3.40E-10"},"rs7084630;10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A;rs56068105:rs7084630:rs56068105:10:5262963_AAC_A",21]
["ENSG00000196326","AKR1CL1",10,5196335,5244449,-1,"protein_coding",340811,"AKR1CL1","NA","NA",69,13.31,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5e-10,"d":"5.00E-10"},"rs7084630;10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A",21]
["ENSG00000198610","AKR1C4",10,5237425,5260912,1,"protein_coding",1109,"AKR1C4",{"v":1.68467759451019e-10,"d":"1.68E-10"},0.954241307,110,13.31,0,"NA","NA","NA","NA","No","NA",{"v":3.4e-10,"d":"3.40E-10"},"rs7084630;10:5262963_AAC_A;rs56068105",21]
["ENSG00000178473","UCN3",10,5406972,5416169,1,"protein_coding",114131,"UCN3",0.508143909845209,-0.445788037,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs7084630:10:5262963_AAC_A;rs56068105",21]
["ENSG00000178462","TUBAL3",10,5435061,5446793,-1,"protein_coding",79861,"TUBAL3",1.70843012375288E-4,0.87987711,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-10,"d":"3.40E-10"},"rs7084630:10:5262963_AAC_A;rs56068105;rs7084630:rs56068105:10:5262963_AAC_A;rs56068105:10:5262963_AAC_A",21]
["ENSG00000173848","NET1",10,5454514,5500426,1,"protein_coding",10276,"NET1",0.0668541946676421,-0.115573761,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-10,"d":"3.40E-10"},"rs7084630:10:5262963_AAC_A;rs56068105;rs7084630:rs56068105:10:5262963_AAC_A;rs56068105:10:5262963_AAC_A",21]
["ENSG00000108021","FAM208B",10,5726801,5805703,1,"protein_coding",54906,"FAM208B",0.96506326510446,-0.778203824,0,0,0,"NA","NA","NA","NA","Yes","IMR90:hESC",{"v":2.3e-08,"d":"2.30E-08"},"10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A",21]
["ENSG00000198879","SFMBT2",10,7200586,7453450,-1,"protein_coding",57713,"SFMBT2",0.996407769866383,-0.14836908,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.3e-08,"d":"2.30E-08"},"10:5262963_AAC_A;rs56068105;rs7084630:10:5262963_AAC_A",21]
["ENSG00000170312","CDK1",10,62538089,62554610,1,"protein_coding",983,"CDK1",0.970572339309587,-0.363031251,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000072422","RHOBTB1",10,62629196,62761198,-1,"protein_coding",9886,"RHOBTB1",0.00183822701018375,-0.452042487,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000183346","C10orf107",10,63422719,63526524,1,"protein_coding",219621,"C10orf107",0.000790930288586529,-0.769889568,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000150347","ARID5B",10,63661059,63856703,1,"protein_coding",84159,"ARID5B",0.999889943413299,-1.139359989,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000182010","RTKN2",10,63942794,64028466,-1,"protein_coding",219790,"RTKN2",{"v":1.30976541627025E-14,"d":"1.31E-14"},2.546277933,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000138311","ZNF365",10,64133951,64431771,1,"protein_coding",22891,"ZNF365",{"v":3.62115394483978e-05,"d":"3.62E-05"},-0.151965448,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000181915","ADO",10,64564516,64568238,1,"protein_coding",84890,"ADO",0.745072785344825,-0.496919278,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000122877","EGR2",10,64571756,64679660,-1,"protein_coding",1959,"EGR2",0.619543204134511,-0.491267292,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesendoderm:hESC",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000148572","NRBF2",10,64893050,64914783,1,"protein_coding",29982,"NRBF2",0.0821062414135336,-0.409712515,9,13.93,3,0.000201484,0.0157243,"GTEx/v8/Artery_Tibial","+","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000171988","JMJD1C",10,64926981,65225722,-1,"protein_coding",221037,"JMJD1C",0.999999999962643,-0.552974329,100,17.64,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000165476","REEP3",10,65281123,65384883,1,"protein_coding",221035,"REEP3",0.0129812993547476,1.398422055,67,15.42,158,{"v":1.33452e-14,"d":"1.33E-14"},{"v":1.80417e-13,"d":"1.80E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.9e-09,"d":"8.90E-09"},"rs538711822",22]
["ENSG00000152804","HHEX",10,94447945,94455403,1,"protein_coding",3087,"HHEX",0.216268139022434,-1.588878356,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":2.1e-09,"d":"2.10E-09"},"rs4418728",23]
["ENSG00000187553","CYP26C1",10,94821021,94828454,1,"protein_coding",340665,"CYP26C1",0.0229549008545053,-0.091096245,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-06,"d":"1.40E-06"},"rs4418728",23]
["ENSG00000095596","CYP26A1",10,94833232,94837647,1,"protein_coding",1592,"CYP26A1",{"v":6.64311184026187e-05,"d":"6.64E-05"},-0.097008268,10,9.498,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.1e-09,"d":"2.10E-09"},"rs4418728",23]
["ENSG00000138119","MYOF",10,95066186,95242074,-1,"protein_coding",26509,"MYOF",{"v":2.08401244116976E-36,"d":"2.08E-36"},-0.140295777,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-09,"d":"2.10E-09"},"rs4418728",23]
["ENSG00000138180","CEP55",10,95256389,95288849,1,"protein_coding",55165,"CEP55",{"v":1.30065957563854E-7,"d":"1.30E-07"},0.140097025,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-09,"d":"2.10E-09"},"rs4418728",23]
["ENSG00000186188","FFAR4",10,95326422,95364237,1,"protein_coding",338557,"FFAR4",0.0055724932654211,2.243003875,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.1e-09,"d":"2.10E-09"},"rs4418728",23]
["ENSG00000138207","RBP4",10,95351444,95361501,-1,"protein_coding",5950,"RBP4",0.57861895575558,-0.611735994,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-06,"d":"1.40E-06"},"rs4418728",23]
["ENSG00000095464","PDE6C",10,95372345,95425767,1,"protein_coding",5146,"PDE6C",{"v":7.4249966167879e-08,"d":"7.42E-08"},0.073360413,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-06,"d":"1.40E-06"},"rs4418728",23]
["ENSG00000148690","FRA10AC1",10,95427640,95462329,-1,"protein_coding",118924,"FRA10AC1",{"v":9.71537508229325e-10,"d":"9.72E-10"},-0.338090023,0,0,2,{"v":1.68685E-5,"d":"1.69E-05"},{"v":3.24095e-11,"d":"3.24E-11"},"GTEx/v8/Pancreas","+","No","NA",{"v":2.1e-09,"d":"2.10E-09"},"rs4418728",23]
["ENSG00000108231","LGI1",10,95517566,95557916,1,"protein_coding",9211,"LGI1",0.997175814162011,-0.476433397,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.4e-06,"d":"1.40E-06"},"rs4418728",23]
["ENSG00000119969","HELLS",10,96305547,96373662,1,"protein_coding",3070,"HELLS",0.999418431126719,0.065854322,0,0,13,{"v":6.22444e-06,"d":"6.22E-06"},{"v":1.74635E-17,"d":"1.75E-17"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":2.2e-09,"d":"2.20E-09"},"rs11596236",24]
["ENSG00000108242","CYP2C18",10,96443251,96495947,1,"protein_coding",1562,"CYP2C18",{"v":5.267291853526e-08,"d":"5.27E-08"},0.613728973,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":2.2e-11,"d":"2.20E-11"},"rs55891451:rs11596236",24]
["ENSG00000165841","CYP2C19",10,96447911,96613017,1,"protein_coding",1557,"CYP2C19",{"v":2.53768601148421e-10,"d":"2.54E-10"},-0.174574379,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":2.2e-11,"d":"2.20E-11"},"rs55891451:rs11596236",24]
["ENSG00000138109","CYP2C9",10,96698415,96749147,1,"protein_coding",1559,"CYP2C9",{"v":2.53599347417585E-8,"d":"2.54E-08"},0.077353466,38,8.103,18,{"v":1.67662e-05,"d":"1.68E-05"},{"v":1.43644e-09,"d":"1.44E-09"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Liver",{"v":1.7e-11,"d":"1.70E-11"},"rs55891451;rs11596236;rs11596236:rs55891451",24]
["ENSG00000138115","CYP2C8",10,96796530,96829254,-1,"protein_coding",1558,"CYP2C8",{"v":5.35039546572966e-12,"d":"5.35E-12"},0.073211053,0,0,21,1.12151E-4,{"v":1.88917e-11,"d":"1.89E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","+","No","NA",{"v":1.7e-11,"d":"1.70E-11"},"rs55891451",24]
["ENSG00000173124","C10orf129",10,96953957,96988685,1,"protein_coding",142827,"C10orf129",0.0112101925841759,-0.050977718,0,0,47,{"v":3.91712E-20,"d":"3.92E-20"},{"v":5.72937e-59,"d":"5.73E-59"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary","+","No","NA",{"v":1.7e-11,"d":"1.70E-11"},"rs55891451;rs11596236",24]
["ENSG00000107438","PDLIM1",10,96997329,97050781,-1,"protein_coding",9124,"PDLIM1",{"v":1.38008290255861E-5,"d":"1.38E-05"},"NA",0,0,31,{"v":3.74346e-05,"d":"3.74E-05"},1.75862E-3,"GTEx/v8/Adipose_Subcutaneous","+","Yes","hESC",{"v":1.7e-11,"d":"1.70E-11"},"rs55891451;rs11596236:rs55891451",24]
["ENSG00000173088","C10orf131",10,97667360,97698480,1,"protein_coding",387707,"C10orf131","NA",1.318571629,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":4.1e-11,"d":"4.10E-11"},"rs11596236:rs55891451",24]
["ENSG00000269948","RP11-248J23.6",10,97709725,97744785,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-11,"d":"1.70E-11"},"rs55891451:rs11596236",24]
["ENSG00000137491","SLCO2B1",11,74811608,74917594,1,"protein_coding",11309,"SLCO2B1",3.35356336964323E-3,0.050758212,0,0,2,{"v":5.2731E-5,"d":"5.27E-05"},0.0450674,"GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":2.3e-11,"d":"2.30E-11"},"rs117249464;rs117008109",25]
["ENSG00000137486","ARRB1",11,74975226,75062873,-1,"protein_coding",408,"ARRB1",0.986801821116486,-0.49885402,0,0,8,{"v":5.38751e-05,"d":"5.39E-05"},0.0390548,"GTEx/v8/Artery_Aorta","-","Yes","EP_correlation_cell_type_oneway",{"v":2.2e-30,"d":"2.20E-30"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678;11:75537738_CT_C",25]
["ENSG00000149243","KLHL35",11,75133438,75141674,-1,"protein_coding",283212,"KLHL35",{"v":1.35038973626761e-12,"d":"1.35E-12"},-0.180877162,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6e-31,"d":"1.60E-31"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs72997616;11:75537738_CT_C;rs72995678:rs72997616;rs72995678:rs150420544",25]
["ENSG00000171533","MAP6",11,75297963,75380165,-1,"protein_coding",4135,"MAP6",0.0131669155399533,-1.145656715,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-33,"d":"1.20E-33"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs72997616;11:75537738_CT_C;rs72995678:rs72997616;rs72995678:rs150420544:11:75664731_AT_A:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs117008109:rs72997672:11:75553487_CT_C:rs72995678:rs673335:rs72997616;rs72995678;rs28811614:rs117249464:rs72997616;rs28811614:rs190387940:rs12221567:rs28811614:rs72997616:rs72997616;rs72997688:rs7119809:rs72997688",25]
["ENSG00000166391","MOGAT2",11,75428864,75444003,1,"protein_coding",80168,"MOGAT2",0.218649112879292,0.716784085,30,11.19,7,{"v":6.32497E-6,"d":"6.32E-06"},{"v":1.3234e-06,"d":"1.32E-06"},"GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-33,"d":"1.20E-33"},"rs72995678;rs673335;rs72997616;rs28811614;rs117249464;rs673335:rs72997616;rs28811614:rs117249464:rs72997616;rs28811614:rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs72997616;11:75537738_CT_C;rs72995678:rs72997616;rs72995678:rs150420544:11:75664731_AT_A:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs117008109:rs72997672:11:75553487_CT_C:rs72997616:rs72997616;rs72997688:rs7119809:rs72997688",25]
["ENSG00000062282","DGAT2",11,75470557,75512579,1,"protein_coding",84649,"DGAT2",{"v":7.51042690362332e-08,"d":"7.51E-08"},-0.634945675,63,13.56,0,"NA","NA","NA","NA","No","NA",{"v":2.9E-32,"d":"2.90E-32"},"rs190387940;rs12221567;rs72997616;rs72995678;rs28811614;rs150420544;rs117249464;rs10899133;11:75539742_GTA_G;rs11236557;11:75537738_CT_C",25]
["ENSG00000198382","UVRAG",11,75526212,75854239,1,"protein_coding",7405,"UVRAG",0.858602500357733,-0.177213177,119,16.46,140,{"v":6.1014e-10,"d":"6.10E-10"},{"v":4.39681e-06,"d":"4.40E-06"},"GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-31,"d":"1.60E-31"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678;11:75537738_CT_C;rs150420544;rs141370279;rs117008109;rs72997672;rs11236557;11:75553487_CT_C;rs72997688;rs7119809;11:75664731_AT_A;rs28811614;rs190387940;rs7119809:rs72997688:11:75537738_CT_C:rs72997616;rs72995678:rs11236557:rs72997616;rs72995678:rs72997616;rs72995678:rs150420544:11:75664731_AT_A:rs72997616:rs72997616",25]
["ENSG00000085741","WNT11",11,75897369,75921780,-1,"protein_coding",7481,"WNT11",0.118580135382174,-0.390232041,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-31,"d":"1.60E-31"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs72997616;11:75537738_CT_C;rs72995678:rs72997616;rs72995678:rs150420544:11:75664731_AT_A:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs117008109:rs72997672:11:75553487_CT_C",25]
["ENSG00000137492","PRKRIR",11,76061000,76092015,-1,"protein_coding",5612,"PRKRIR",0.968969189254267,-0.304434935,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-31,"d":"1.60E-31"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs7119809:rs72997688:rs72997616;11:75537738_CT_C;rs72995678:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:11:75664731_AT_A:rs72997616;rs72995678:rs150420544:rs117008109:rs72997672:11:75553487_CT_C",25]
["ENSG00000179240","RP11-111M22.2",11,76092357,76125663,1,"protein_coding",100506127,"GVQW3","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-31,"d":"1.60E-31"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs7119809:rs72997688:rs72997616;11:75537738_CT_C;rs72995678:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:11:75664731_AT_A:rs72997616;rs72995678:rs150420544:rs117008109:rs72997672:11:75553487_CT_C",25]
["ENSG00000158636","C11orf30",11,76155967,76264069,1,"protein_coding",56946,"C11orf30",0.999997096766169,-0.811740869,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.4E-8,"d":"2.40E-08"},"11:75664731_AT_A",25]
["ENSG00000137507","LRRC32",11,76368568,76381791,-1,"protein_coding",2615,"LRRC32",0.0215755256662984,1.347358259,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-31,"d":"1.60E-31"},"rs72997616;rs10899133;11:75539742_GTA_G;rs72995678:rs11236557:rs72997616;11:75537738_CT_C;rs72995678:rs72997616;rs72995678:rs150420544:11:75664731_AT_A:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs117008109:rs72997672:11:75553487_CT_C",25]
["ENSG00000182704","TSKU",11,76493295,76509198,1,"protein_coding",25987,"TSKU",0.729712730834786,-0.66270525,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.4E-8,"d":"2.40E-08"},"11:75664731_AT_A",25]
["ENSG00000166682","TMPRSS5",11,113558272,113577095,-1,"protein_coding",80975,"TMPRSS5",{"v":2.57785706102948E-8,"d":"2.58E-08"},0.18379421,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.3E-15,"d":"1.30E-15"},"11:116526032_CCT_C",26]
["ENSG00000048028","USP28",11,113668596,113746292,-1,"protein_coding",57646,"USP28",0.031657505195455,0.869552466,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3e-82,"d":"3.00E-82"},"11:116526032_CCT_C:rs56224630;rs6589563:rs1269325:rs11216127:rs142958146:rs12791103;rs11216127:rs2266788:rs56224630:rs59034260:rs180327:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353",26]
["ENSG00000166736","HTR3A",11,113845603,113861035,1,"protein_coding",3359,"HTR3A",{"v":1.02839422335736E-9,"d":"1.03E-09"},-0.005129549,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":4.7e-27,"d":"4.70E-27"},"rs12718462:rs688456:rs10047462;11:116837730_AG_A:rs1374117;rs78442878:rs35477610;rs7117123;rs146811643:rs7117123:rs10047462;rs90192;11:116837730_AG_A:rs5128;rs10047462:rs688456;rs12718462:11:116837730_AG_A;11:117019749_ATTT_A:rs7117123;rs146811643:11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135",26]
["ENSG00000109906","ZBTB16",11,113930315,114121398,1,"protein_coding",7704,"ZBTB16",0.980087305825708,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3e-82,"d":"3.00E-82"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135:rs56224630;rs6589563:rs1269325:rs11216127:rs142958146:rs12791103;rs11216127:rs2266788:rs56224630:rs59034260:rs180327:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353",26]
["ENSG00000166741","NNMT",11,114128509,114184007,1,"protein_coding",4837,"NNMT",0.00427916395502723,-0.273618136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135:rs12718462:rs35477610;rs7117123;rs146811643:rs5128;rs10047462:rs1374117;rs78442878:rs688456:rs10047462;11:116837730_AG_A:rs35477610;rs146811643;rs12718462:rs10047462;rs201496069;11:116837730_AG_A:rs10047462;rs90192;11:116837730_AG_A:rs688456;rs12718462:rs139524394:11:116837730_AG_A:11:116569272_TA_T:rs1269325:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs2266788:rs6589563:11:116593824_GC_G:rs56224630;rs6589563:rs141414463:rs180327:rs11216127:rs142958146:rs12791103;rs11216127:rs56224630:rs59034260:rs964184;rs11604424:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs10047462;rs508487;rs236911:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs236911:rs236913:rs7117123:rs90192;rs236911:rs4018880;rs11419184;rs139857231:rs7118999:rs12791103:rs964184:rs11604424:rs6589567:rs1263164:rs7111242:rs111905938:rs78442878:rs78442878;rs688456",26]
["ENSG00000180425","C11orf71",11,114262165,114271139,-1,"protein_coding",54494,"C11orf71",0.00842481501256066,-0.124748547,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135:11:116569272_TA_T:rs1269325:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs2266788:rs6589563:11:116593824_GC_G:rs56224630;rs6589563:rs141414463:rs180327:rs11216127:rs142958146:rs12791103;rs11216127:rs56224630:rs59034260:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs7118999:rs12791103:rs964184:rs11604424:rs6589567:rs1263164:rs7111242:rs10047462;rs508487;rs90192;rs236911:rs12718462:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs236911:rs236913:rs7117123:rs90192;rs236911:rs4018880;rs11419184;rs201496069;rs139857231",26]
["ENSG00000076053","RBM7",11,114270752,114284925,1,"protein_coding",10179,"RBM7",0.769935289328386,-0.240422903,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135:11:116569272_TA_T:rs1269325:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs2266788:rs6589563:11:116593824_GC_G:rs56224630;rs6589563:rs141414463:rs180327:rs11216127:rs142958146:rs12791103;rs11216127:rs56224630:rs59034260:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs7118999:rs12791103:rs964184:rs11604424:rs6589567:rs1263164:rs7111242:rs10047462;rs508487;rs90192;rs236911:rs12718462:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs236911:rs236913:rs7117123:rs90192;rs236911:rs4018880;rs11419184;rs201496069;rs139857231",26]
["ENSG00000255663","RP11-212D19.4",11,114271404,114314654,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135:11:116569272_TA_T:rs1269325:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs2266788:rs6589563:11:116593824_GC_G:rs56224630;rs6589563:rs141414463:rs180327:rs11216127:rs142958146:rs12791103;rs11216127:rs56224630:rs59034260:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs7118999:rs12791103:rs964184:rs11604424:rs6589567:rs1263164:rs7111242:rs10047462;rs508487;rs90192;rs236911:rs12718462:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs236911:rs236913:rs7117123:rs90192;rs236911:rs4018880;rs11419184;rs201496069;rs139857231",26]
["ENSG00000076043","REXO2",11,114310108,114321001,1,"protein_coding",25996,"REXO2",0.888428672321779,-0.470637003,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116526032_CCT_C:rs56224630;rs6589563:rs1269325:rs11216127:rs142958146:rs12791103;rs11216127:rs2266788:rs56224630:rs59034260:rs180327:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs57984552:rs61905060:rs17092642:11:116569272_TA_T:rs11824135;rs61905060:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs6589563:11:116593824_GC_G:rs141414463:rs7118999:rs12791103:rs964184:rs11604424:rs6589567:rs1263164:rs7111242",26]
["ENSG00000095110","NXPE1",11,114392437,114430617,-1,"protein_coding",120400,"NXPE1",{"v":3.48609216284613e-10,"d":"3.49E-10"},0.560244834,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-15,"d":"1.30E-15"},"11:116526032_CCT_C",26]
["ENSG00000137634","NXPE4",11,114441313,114466484,-1,"protein_coding",54827,"NXPE4",{"v":2.74741341116275e-08,"d":"2.75E-08"},-0.225836593,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":1.3E-15,"d":"1.30E-15"},"11:116526032_CCT_C",26]
["ENSG00000204361","NXPE2",11,114549108,114579362,1,"protein_coding",120406,"NXPE2",0.244911849376349,-0.045975215,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.4e-40,"d":"5.40E-40"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135:11:116569272_TA_T:rs1269325:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs2266788:rs6589563:11:116593824_GC_G:rs56224630;rs6589563:rs141414463:rs180327",26]
["ENSG00000182985","CADM1",11,115039938,115375675,-1,"protein_coding",23705,"CADM1",0.99438640410443,-1.276282249,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.7e-27,"d":"4.70E-27"},"11:116526032_CCT_C:rs61905060:rs486394:rs57984552:rs11824135;rs61905060:rs17092642:rs509728:rs11824135;rs61905060;rs17092642:rs11824135",26]
["ENSG00000137656","BUD13",11,116618886,116643704,-1,"protein_coding",84811,"BUD13",2.29542848916745E-3,"NA",84,20.2,2,{"v":9.98962e-06,"d":"9.99E-06"},0.0476398,"GTEx/v8/Artery_Coronary","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs1269325;rs56224630;rs6589563;rs11216127;rs2266788;rs180327;rs12791103;rs964184;rs11604424;rs139524394;rs143811287;rs17440824;11:116638691_AAAT_A;rs1268353;rs142958146;rs7118999;rs61905060;rs12718462:rs78442878:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;rs201496069;11:116837730_AG_A;rs236911:rs34796476:rs4018880;rs11419184;rs139857231:rs139857231;11:117019749_ATTT_A:rs11449159:rs7117123:rs10047462;rs236911;11:117019749_ATTT_A:rs90192;rs139857231;11:117019749_ATTT_A:rs90192:rs508487:rs74620484:rs1263164:rs7111242:rs7111242;rs4018880:rs4018880:rs525028:rs1374117:rs688456:rs1374117;rs78442878:rs6144523:rs525028;rs35477610;rs7117123;rs6144523:11:116837730_AG_A:rs5128;rs10047462:rs525028;rs7117123:rs35477610;rs7117123:rs10047462;11:116837730_AG_A:rs35477610;rs146811643:rs10047462:11:116837730_AG_A;11:117019749_ATTT_A:rs139524394:rs688456;rs12718462:rs7117123;rs146811643:rs10047462;11:116837730_AG_A:rs508487;rs90192:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:11:116593824_GC_G:rs11419184;rs139857231:rs139857231:11:116837730_AG_A;rs139857231:rs201496069:rs201496069;11:117019749_ATTT_A:11:117019749_ATTT_A:rs508487;rs236911:rs56224630;rs6589563:rs1269325:rs11216127:rs142958146:rs12791103;rs11216127:rs2266788:rs56224630:rs59034260:rs10047462;rs508487;rs236911:rs141594094;rs1374117;rs78442878:rs78442878;rs688456:rs11419184:rs90192;rs139857231:rs180327:rs964184;rs11604424:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs10047462;rs90192:rs35477610:rs141594094:rs35477610;rs146811643;rs12718462:rs10047462;rs236911:rs10047462;rs236911:rs236911:rs236913:rs90192;rs236911:11:116593824_GC_G;rs28917234:rs28917234",26]
["ENSG00000109917","ZNF259",11,116648436,116658766,-1,"protein_coding",8882,"ZNF259",0.0193034953229086,0.002394641,48,23.3,41,{"v":3.77408e-06,"d":"3.77E-06"},0.000361971,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"11:116638691_AAAT_A;rs2266788;rs1268353;rs1269325;rs142958146;rs7118999;rs139524394;rs12791103;rs56224630;rs964184;rs11604424;rs6589567;rs6589563;rs688456:rs12718462:rs78442878:rs10047462;rs90192;rs11449159;rs201496069;11:116837730_AG_A;rs236911:rs139857231;11:117019749_ATTT_A:rs10047462;11:116837730_AG_A:rs34796476:rs10047462;rs236911;11:117019749_ATTT_A:11:116837730_AG_A;rs139857231:rs201496069:rs7117123:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A:rs1263164:rs7111242:rs7111242;rs4018880:rs4018880:rs525028:rs1374117:rs1374117;rs78442878:rs6144523:rs525028;rs35477610;rs7117123;rs6144523:11:116837730_AG_A:rs5128;rs10047462:rs525028;rs7117123:rs35477610;rs7117123:rs10047462;11:116837730_AG_A:rs35477610;rs146811643:rs141594094;rs1374117;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs10047462:rs10047462;rs90192:11:116593824_GC_G:rs35477610:rs139524394:rs688456;rs12718462:rs10047462;11:116837730_AG_A:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs11419184;rs139857231:rs139857231:rs4018880;rs11419184;rs139857231:rs508487;rs236911:11:116593824_GC_G;rs28917234:rs56224630;rs6589563:rs1269325:rs11216127:rs142958146:rs12791103;rs11216127:rs2266788:rs56224630:rs59034260:rs10047462;rs508487;rs236911:rs90192:rs90192;11:117019749_ATTT_A:rs508487:rs74620484:rs78442878;rs688456:rs11419184:rs90192;rs139857231:rs180327:rs964184;rs11604424:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs141594094:rs35477610;rs146811643;11:116837730_AG_A:rs10047462;rs236911:rs10047462;rs236911:rs236911:rs236913:rs90192;rs236911:rs28917234",26]
["ENSG00000110243","APOA5",11,116660083,116663136,-1,"protein_coding",116519,"APOA5",{"v":1.37735073361006e-06,"d":"1.38E-06"},0.423730278,41,23.3,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3e-82,"d":"3.00E-82"},"rs56224630;rs12791103;rs11604424;rs2266788;rs1269325;rs964184;rs142958146;rs7118999;rs6589567;rs2070669:rs5128;rs7111242;rs4018880:rs525028:rs1374117:rs5128;rs7111242:rs5128:rs5128;rs4018880:rs525028;rs7117123:rs688456:rs12718462:rs5128;rs10047462:rs7117123:rs35477610;rs7117123;rs146811643:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;11:116837730_AG_A:rs78442878:rs10047462;rs201496069;11:116837730_AG_A;rs236911:rs34796476:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs139857231;11:117019749_ATTT_A:11:116593824_GC_G:rs11419184;rs139857231:rs10047462;rs236911;11:117019749_ATTT_A:rs139857231:11:116837730_AG_A;rs139857231:rs201496069:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A:rs4018880;rs11419184;rs508487;rs236911:rs10047462;rs236911:rs236911:rs236913:rs90192;rs236911:rs508487;rs236911:rs90192:rs90192;11:117019749_ATTT_A:rs508487:rs74620484:rs525028;rs35477610;rs6144523:11:116837730_AG_A:rs10047462:rs1374117;rs78442878:rs525028;rs7117123:rs35477610;rs7117123:rs10047462;11:116837730_AG_A:rs141594094;rs1374117;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs688456;rs12718462:rs78442878;rs688456:rs11419184:rs90192;rs139857231:rs56224630;rs6589563:rs1269325:rs11216127:rs142958146:rs12791103;rs11216127:rs2266788:rs56224630:rs59034260:rs180327:rs964184;rs11604424:rs139524394:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs10047462;rs90192:rs35477610:rs141594094:rs35477610;rs146811643;rs12718462:rs10047462;11:116837730_AG_A:11:116593824_GC_G;rs28917234:rs28917234",26]
["ENSG00000110244","APOA4",11,116691419,116694022,-1,"protein_coding",337,"APOA4",{"v":3.57595118139907e-05,"d":"3.58E-05"},0.081655096,34,23.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.1e-30,"d":"2.10E-30"},"rs7111242;rs1263164;rs4018880;rs139524394;rs12721041;11:116593824_GC_G;rs2070669;rs5128;rs525028;rs1374117;rs7117123;rs4018880:rs525028:rs1374117:rs688456:rs1374117;rs78442878:rs6144523:rs525028;rs35477610;rs6144523:rs12718462:11:116837730_AG_A:rs35477610;rs146811643:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;11:116837730_AG_A:rs78442878:rs10047462;rs201496069;11:116837730_AG_A;rs236911:rs34796476:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs139857231;11:117019749_ATTT_A:11:116593824_GC_G:rs11419184;rs139857231:rs10047462;rs236911;11:117019749_ATTT_A:rs139857231:rs7117123:rs11419184:11:116837730_AG_A;rs139857231:rs4018880;rs11419184;rs139857231:rs508487:rs90192;rs139857231:rs201496069:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A",26]
["ENSG00000110245","APOC3",11,116700422,116703788,1,"protein_coding",345,"APOC3",0.00067802640410586,0.121255473,49,23.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-50,"d":"1.40E-50"},"rs139524394;rs7111242;rs4018880;rs12721041;11:116593824_GC_G;rs2070669;rs5128;rs525028;rs1374117;rs7117123;rs688456;rs12718462;rs10047462;rs78442878;rs6144523;rs35477610;rs142958146:rs2266788:rs56224630:rs12791103:rs7118999:rs1269325:rs6589567:rs35477610;rs146811643:rs688456:rs12718462:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;11:116837730_AG_A:rs78442878:rs10047462;rs201496069;11:116837730_AG_A;rs236911:rs34796476:rs139857231;11:117019749_ATTT_A:rs4018880;rs11419184;rs139857231:rs10047462;rs508487;rs236911:rs90192:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:11:116593824_GC_G:rs11419184;rs236911;11:117019749_ATTT_A:rs139857231:rs7117123:rs11419184:11:116837730_AG_A;rs139857231:rs508487:rs90192;rs139857231:rs201496069:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A",26]
["ENSG00000118137","APOA1",11,116706467,116708666,-1,"protein_coding",335,"APOA1",0.0487383759438174,0.161101272,48,12.11,546,{"v":2.81438e-35,"d":"2.81E-35"},{"v":9.81014e-29,"d":"9.81E-29"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-50,"d":"1.40E-50"},"rs12721041;11:116593824_GC_G;rs2070669;rs5128;rs7111242;rs4018880;rs525028;rs1374117;rs7117123;rs688456;rs12718462;rs10047462;rs78442878;rs6144523;rs35477610;rs1263164;rs141594094;rs146811643;rs56224630;rs6589563;rs7118999;rs12791103;11:116837730_AG_A;rs139857231;rs236913;rs142958146:rs2266788:rs56224630:rs12791103:rs7118999:rs1269325:rs6589567:rs35477610;rs146811643:rs688456:rs12718462:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;11:116837730_AG_A:rs78442878:rs10047462;rs201496069;rs236911:rs34796476:rs139857231;11:117019749_ATTT_A:rs4018880;rs11419184;rs139857231:rs10047462;rs508487;rs236911:rs90192:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:11:116593824_GC_G:rs11419184;rs236911;11:117019749_ATTT_A:rs139857231:rs7117123:rs11419184:11:116837730_AG_A;rs139857231:rs508487:rs90192;rs139857231:rs201496069:rs201496069;11:117019749_ATTT_A:11:117019749_ATTT_A",26]
["ENSG00000160584","SIK3",11,116714118,116969153,-1,"protein_coding",23387,"SIK3",0.999882540750175,0.278236341,533,22.9,140,{"v":6.70574e-11,"d":"6.71E-11"},{"v":1.08311e-06,"d":"1.08E-06"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs5128;rs1374117;rs688456;rs525028;rs12718462;rs4018880;rs10047462;rs7117123;rs78442878;rs6144523;rs35477610;11:116837730_AG_A;rs90192;rs141594094;11:117019749_ATTT_A;rs146811643;11:116593824_GC_G;rs201496069;rs139524394;rs111905938;rs11449159;rs236911;rs139857231;rs11419184;11:116837730_AG_A:rs35477610;rs7117123:rs12718462:rs35477610;rs146811643:rs142958146:rs2266788:rs56224630:rs12791103:rs7118999:rs1269325:rs6589567:rs143811287:rs1263164:rs7111242:rs139524394:rs7111242;rs4018880:rs12721041:11:116593824_GC_G:rs2070669:rs5128;rs7111242;rs4018880:rs525028:rs1374117:rs5128;rs7111242:rs5128:rs5128;rs4018880:rs525028;rs7117123:rs688456:rs5128;rs10047462:rs7117123:rs525028;rs6144523:11:116837730_AG_A:rs10047462:rs1374117;rs78442878:rs525028;rs7117123:rs10047462;11:116837730_AG_A:rs141594094;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs10047462;rs90192:rs35477610:rs141594094:rs78442878:rs688456;rs12718462:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs964184:rs11604424:rs964184;rs11604424:rs4018880:rs6144523:rs7117123;rs146811643:rs111905938:rs78442878;rs688456:rs146811643:rs525028;rs7117123:rs11449159:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs11419184;rs139857231:rs10047462;11:117019749_ATTT_A:rs139857231:11:116837730_AG_A;rs139857231:rs201496069:rs201496069;11:117019749_ATTT_A:11:117019749_ATTT_A:rs4018880;rs139857231:rs508487;rs236911:11:116593824_GC_G;rs28917234:rs35477610;rs12718462:rs10047462;11:116837730_AG_A:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs10047462;rs508487;rs236911:rs10047462;rs236911:rs236911:rs236913:rs90192;rs236911:rs90192:rs90192;11:117019749_ATTT_A:rs508487:rs74620484",26]
["ENSG00000168092","PAFAH1B2",11,117014983,117047610,1,"protein_coding",5049,"PAFAH1B2",0.962029472445706,3.356774148,111,18.4,20,{"v":2.87039e-06,"d":"2.87E-06"},0.00428504,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs139857231;rs12718462;rs90192;rs11419184;rs201496069;rs7117123;rs10047462;rs11449159;11:116837730_AG_A;rs236911;11:117019749_ATTT_A;rs4018880;rs508487;rs78442878;rs146811643;rs56224630:rs12791103:rs11604424:rs2266788:rs1269325:rs964184;rs11604424:rs142958146:rs7118999:rs6589567:rs7117123:rs525028;rs35477610;rs6144523:11:116837730_AG_A:rs10047462:rs688456:rs1374117;rs78442878:rs525028:rs12718462:rs525028;rs7117123:rs10047462;11:116837730_AG_A:rs139857231;11:117019749_ATTT_A:rs4018880;rs139857231:rs10047462;rs236911:rs90192:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs139524394:rs964184:rs1263164:rs7111242:rs7111242;rs4018880:rs4018880:rs1374117:rs6144523:rs5128;rs10047462:rs35477610;11:116837730_AG_A:rs35477610;rs146811643:rs141594094;rs1374117;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs10047462;rs90192:11:116593824_GC_G:rs35477610:rs688456;rs12718462:rs7117123;rs146811643:rs78442878;rs688456:rs10047462;11:116837730_AG_A:rs78442878:rs10047462;rs236911:rs34796476:rs508487;rs90192:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs11419184;11:117019749_ATTT_A:rs139857231:rs508487;rs236911:11:116593824_GC_G;rs28917234:rs28917234:rs143811287:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs12721041:rs2070669:rs5128;rs7111242;rs4018880:rs5128;rs7111242:rs5128:rs5128;rs4018880:rs525028;rs7117123:rs141594094:rs90192;11:117019749_ATTT_A:rs508487:rs74620484:rs35477610;rs12718462:rs10047462",26]
["ENSG00000149577","SIDT2",11,117049449,117068160,1,"protein_coding",51092,"SIDT2",0.00257240105871232,-0.315317931,73,14.11,558,{"v":9.00793e-29,"d":"9.01E-29"},{"v":1.17121e-22,"d":"1.17E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs12718462;rs4018880;rs90192;rs11419184;rs201496069;rs139857231;rs7117123;rs10047462;rs11449159;11:116837730_AG_A;rs236911;11:117019749_ATTT_A;rs508487;rs78442878;rs688456;rs525028;rs7111242;rs1263164;rs2070669;rs5128;rs35477610;rs6144523;rs146811643;rs12718462:rs139857231;11:117019749_ATTT_A:rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs1263164:rs7111242:rs7111242;rs4018880:rs4018880:rs525028:rs1374117:rs688456:rs1374117;rs78442878:rs6144523:rs525028;rs6144523:11:116837730_AG_A:rs5128;rs10047462:rs525028;rs7117123:rs10047462;11:116837730_AG_A:rs35477610;rs146811643:rs141594094;rs1374117;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs10047462:rs10047462;rs90192:11:116593824_GC_G:rs35477610:rs7117123:rs688456;rs12718462:rs7117123;rs146811643:rs78442878;rs688456:rs10047462;11:116837730_AG_A:rs78442878:rs10047462;rs236911:rs34796476:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs11419184;rs139857231:rs10047462;11:117019749_ATTT_A:rs139857231:11:116837730_AG_A;rs139857231:rs201496069:rs201496069;11:117019749_ATTT_A:11:117019749_ATTT_A:rs90192;11:117019749_ATTT_A:rs90192:rs508487:rs74620484:11:116593824_GC_G;rs28917234:rs28917234:rs6589567:rs143811287:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs141594094:rs11419184:rs4018880;rs139857231:rs90192;rs139857231:rs35477610;rs12718462:rs10047462;11:116837730_AG_A:rs508487",26]
["ENSG00000149591","TAGLN",11,117070037,117075498,1,"protein_coding",6876,"TAGLN",0.241537680178233,-0.645790474,46,16.39,245,{"v":3.70697E-19,"d":"3.71E-19"},{"v":7.71611E-14,"d":"7.72E-14"},"GTEx/v8/Pancreas","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs12718462;rs4018880;rs90192;rs11419184;rs201496069;rs139857231;rs10047462;rs508487;rs11449159;rs236911;11:117019749_ATTT_A;rs74620484;rs1263164;rs7111242;rs5128;rs525028;rs7117123;rs35477610;rs6144523;11:116837730_AG_A;rs146811643;rs236913;rs12718462:rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs6589567:rs143811287:rs1263164:rs7111242:rs7111242;rs4018880:rs688456:rs35477610;rs7117123:rs141594094;rs1374117;rs78442878:rs10047462;11:116837730_AG_A:11:116837730_AG_A;11:117019749_ATTT_A:rs7117123:rs11419184:11:116837730_AG_A;rs139857231:rs139857231;11:117019749_ATTT_A:rs10047462;11:117019749_ATTT_A:rs4018880;rs139857231:rs508487:rs139857231:rs90192;rs139857231:rs5128;rs10047462:rs525028;rs7117123:rs10047462;11:116837730_AG_A:rs1374117;rs78442878:rs508487;rs236911:rs78442878:rs11604424:rs964184;rs11604424:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs525028;rs6144523:11:116837730_AG_A:rs10047462:rs525028:rs35477610;rs146811643:rs10047462;rs90192:11:116593824_GC_G:rs35477610:rs141594094:rs688456;rs12718462:rs7117123;rs146811643:rs201496069:rs201496069;11:117019749_ATTT_A:11:117019749_ATTT_A:rs11449159:rs35477610;rs12718462:rs10047462;11:116837730_AG_A:rs10047462;rs236911:rs34796476:rs508487;rs90192:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11419184",26]
["ENSG00000160613","PCSK7",11,117075053,117103241,-1,"protein_coding",9159,"PCSK7",0.191369613352617,"NA",53,16.39,26,{"v":6.85066e-06,"d":"6.85E-06"},{"v":3.95162E-7,"d":"3.95E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs12718462;rs139857231;11:117019749_ATTT_A;rs4018880;rs90192;rs11419184;rs201496069;rs508487;rs74620484;rs10047462;rs236911;rs236913;rs7117123;11:116837730_AG_A;rs1263164:rs7111242:rs7111242;rs4018880:rs35477610;rs146811643:rs12718462:rs5128;rs10047462:rs688456:rs10047462;11:116837730_AG_A:rs10047462;rs11449159;11:116837730_AG_A:rs78442878:rs10047462;rs236911:rs34796476:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs139857231;11:117019749_ATTT_A:11:116593824_GC_G:rs11419184;rs139857231:rs10047462;11:117019749_ATTT_A:rs139857231:rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:11:116593824_GC_G;rs28917234:rs28917234:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs7117123:rs525028;rs35477610;rs6144523:11:116837730_AG_A:rs10047462:rs1374117;rs78442878:rs525028:rs525028;rs7117123:rs35477610;rs7117123:rs10047462;11:116837730_AG_A:rs141594094;rs1374117;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs10047462;rs90192:rs35477610:rs141594094:rs35477610;rs146811643;rs12718462:rs10047462;11:116837730_AG_A:rs688456",26]
["ENSG00000167257","RNF214",11,117103341,117157161,1,"protein_coding",257160,"RNF214",0.830018244677536,"NA",2,3.119,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.9e-85,"d":"3.90E-85"},"rs7117123;rs236913;rs1263164:rs7111242:rs7111242;rs4018880:rs35477610;rs146811643:rs12718462:rs5128;rs10047462:rs688456:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;11:116837730_AG_A:rs78442878:rs10047462;rs201496069;11:116837730_AG_A;rs236911:rs34796476:rs508487;rs90192:rs7117123;rs146811643:rs146811643:rs111905938:rs525028;rs111905938;rs7117123:rs11449159:rs139857231;11:117019749_ATTT_A:11:116593824_GC_G:rs11419184;rs139857231:rs10047462;rs236911;11:117019749_ATTT_A:rs139857231:rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:11:116593824_GC_G;rs28917234:rs28917234:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs7117123:rs525028;rs35477610;rs6144523:11:116837730_AG_A:rs10047462:rs1374117;rs78442878:rs525028:rs525028;rs7117123:rs35477610;rs7117123:rs10047462;11:116837730_AG_A:rs141594094;rs1374117;rs78442878:11:116837730_AG_A;11:117019749_ATTT_A:rs10047462;rs90192:rs35477610:rs141594094:rs35477610;rs146811643;rs12718462:rs10047462;11:116837730_AG_A:rs688456;rs12718462",26]
["ENSG00000186318","BACE1",11,117156402,117186975,-1,"protein_coding",23621,"BACE1",0.944278809144277,-0.919089932,2,17.44,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116593824_GC_G;rs28917234;rs12718462:rs139857231;11:117019749_ATTT_A:rs10047462;rs90192;rs11449159;rs201496069;11:116837730_AG_A;rs236911;11:117019749_ATTT_A:11:116837730_AG_A;rs139857231:rs201496069:rs7117123:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A:rs4018880;rs11419184;rs139857231:rs508487;rs236911:rs78442878:rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:rs1263164:rs7111242:rs10047462;rs508487;rs236911:rs10047462;rs236911:rs236911:rs236913:rs90192",26]
["ENSG00000110274","CEP164",11,117185273,117283984,1,"protein_coding",22897,"CEP164",{"v":9.66879225304467e-18,"d":"9.67E-18"},0.753351641,2,17.44,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"11:116593824_GC_G;rs28917234;rs12718462:rs10047462;rs90192;rs11449159;rs201496069;11:116837730_AG_A;rs236911;11:117019749_ATTT_A:11:116837730_AG_A;rs139857231:rs139857231;11:117019749_ATTT_A:rs201496069:rs7117123:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A:rs4018880;rs11419184;rs139857231:rs508487;rs236911:rs78442878:rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:rs1263164:rs7111242:rs10047462;rs508487;rs236911:rs10047462;rs236911:rs236911:rs236913:rs90192",26]
["ENSG00000110324","IL10RA",11,117857063,117872196,1,"protein_coding",3587,"IL10RA",0.968345855815418,-0.921352137,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.3E-15,"d":"1.30E-15"},"11:116526032_CCT_C",26]
["ENSG00000137648","TMPRSS4",11,117947753,117992605,1,"protein_coding",56649,"TMPRSS4",{"v":1.19754386539244e-08,"d":"1.20E-08"},0.384951766,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.4e-40,"d":"5.40E-40"},"11:116526032_CCT_C:rs57984552:rs61905060:rs17092642:11:116569272_TA_T:rs11824135;rs61905060:rs1269325:rs12221682:rs61905067:rs11216107:rs56224630;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642:rs6589563;rs61905060:rs2266788:rs6589563:11:116593824_GC_G:rs56224630;rs6589563:rs141414463:rs180327",26]
["ENSG00000110344","UBE4A",11,118230300,118269926,1,"protein_coding",9354,"UBE4A",0.937619432134248,0.396074413,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.3E-14,"d":"1.30E-14"},"rs35477610;rs7117123;rs146811643:rs688456:rs12718462:rs10047462;11:116837730_AG_A:rs10047462;rs90192;rs11449159;11:116837730_AG_A:rs7117123:rs10047462;rs201496069;11:116837730_AG_A;rs236911;11:117019749_ATTT_A:rs4018880;rs11419184;rs139857231:rs508487;rs236911:rs78442878:rs139857231;11:117019749_ATTT_A:11:116837730_AG_A;rs139857231:rs201496069:rs201496069;rs139857231;11:117019749_ATTT_A:11:117019749_ATTT_A",26]
["ENSG00000254873","RP11-770J1.5",11,118267810,118272610,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:rs1263164:rs7111242:rs10047462;rs508487;rs90192;rs236911:rs12718462:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs236911:rs236913:rs7117123:rs90192;rs236911:rs4018880;rs11419184;rs201496069;rs139857231:11:116593824_GC_G;rs28917234:rs28917234:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353",26]
["ENSG00000167283","ATP5L",11,118271869,118302211,1,"protein_coding",10632,"ATP5L",0.337891181698725,-0.416063281,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-85,"d":"3.90E-85"},"rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:rs1263164:rs7111242:rs10047462;rs508487;rs90192;rs236911:rs12718462:rs10047462;rs236911:rs139857231;11:117019749_ATTT_A:rs236911:rs236913:rs7117123:rs90192;rs236911:rs4018880;rs11419184;rs201496069;rs139857231:11:116593824_GC_G;rs28917234:rs28917234:rs56224630;rs6589563:rs11216127:rs12791103;rs11216127:rs59034260:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353",26]
["ENSG00000255384","RP11-770J1.4",11,118303836,118305921,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.9e-85,"d":"3.90E-85"},"rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:rs1263164:rs7111242",26]
["ENSG00000118058","KMT2A",11,118307205,118397539,1,"protein_coding",4297,"KMT2A",1,-1.788949198,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.9e-85,"d":"3.90E-85"},"rs2266788:rs1269325:rs142958146:rs7118999:rs139524394:rs12791103:rs56224630:rs964184:rs11604424:rs964184;rs11604424:rs6589567:rs143811287:rs1263164:rs7111242",26]
["ENSG00000149582","TMEM25",11,118401756,118417995,1,"protein_coding",84866,"TMEM25",0.00042136891544107,1.146697877,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.1E-12,"d":"1.10E-12"},"rs7117123:rs12718462:rs10047462;rs90192;rs11449159;rs201496069;11:116837730_AG_A;rs236911;11:117019749_ATTT_A:rs4018880;rs11419184;rs139857231:rs508487;rs236911:rs78442878:rs139857231;11:117019749_ATTT_A",26]
["ENSG00000089159","PXN",12,120648250,120703574,-1,"protein_coding",5829,"PXN",0.00656841085846847,-0.711885213,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.3e-05,"d":"7.30E-05"},"rs7970695",27]
["ENSG00000089163","SIRT4",12,120740119,120751052,1,"protein_coding",23409,"SIRT4",{"v":1.80676632025049E-7,"d":"1.81E-07"},-0.347424539,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.8E-5,"d":"2.80E-05"},"rs7970695",27]
["ENSG00000111775","COX6A1",12,120875893,120878545,1,"protein_coding",1337,"COX6A1",0.0609575623120839,0.176100304,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.3e-05,"d":"7.30E-05"},"rs7970695",27]
["ENSG00000111780","AL021546.6",12,120876001,120897809,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.3e-05,"d":"7.30E-05"},"rs7970695",27]
["ENSG00000111786","SRSF9",12,120899471,120907596,-1,"protein_coding",8683,"SRSF9",0.819638672376706,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000088986","DYNLL1",12,120907653,120936296,1,"protein_coding",8655,"DYNLL1",0.696580483081237,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000110871","COQ5",12,120941077,120972237,-1,"protein_coding",84274,"COQ5",{"v":7.95018460631921e-05,"d":"7.95E-05"},0.02662786,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.8E-5,"d":"2.80E-05"},"rs7970695",27]
["ENSG00000022840","RNF10",12,120971283,121015397,1,"protein_coding",9921,"RNF10",0.502963048424231,0.037115157,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.8E-5,"d":"2.80E-05"},"rs7970695",27]
["ENSG00000167272","POP5",12,121016567,121019201,-1,"protein_coding",51367,"POP5",{"v":1.28002317887135E-5,"d":"1.28E-05"},-0.243976841,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.1e-08,"d":"8.10E-08"},"rs7970695",27]
["ENSG00000157782","CABP1",12,121078355,121105127,1,"protein_coding",9478,"CABP1",0.994401234059643,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000110917","MLEC",12,121124672,121139667,1,"protein_coding",9761,"MLEC",0.470920638317783,1.033373744,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.6e-09,"d":"1.60E-09"},"rs7970695",27]
["ENSG00000175970","UNC119B",12,121148238,121161443,1,"protein_coding",84747,"UNC119B",0.677325341021738,0.550413245,0,0,3,{"v":2.45816e-05,"d":"2.46E-05"},0.000626415,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.6e-09,"d":"1.60E-09"},"rs7970695",27]
["ENSG00000157837","SPPL3",12,121200313,121342174,-1,"protein_coding",121665,"SPPL3",0.907785634336426,0.151809144,0,0,15,{"v":8.62277e-07,"d":"8.62E-07"},{"v":3.87548e-20,"d":"3.88E-20"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","No","NA",{"v":8.1e-08,"d":"8.10E-08"},"rs7970695",27]
["ENSG00000272214","AC079602.1",12,121407641,121410095,-1,"protein_coding","NA","NA","NA","NA",8,10.21,0,"NA","NA","NA","NA","No","NA",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000135100","HNF1A",12,121416346,121440315,1,"protein_coding",6927,"HNF1A",0.969659467322862,-0.628781489,35,10.21,0,"NA","NA","NA","NA","No","NA",{"v":1.6e-09,"d":"1.60E-09"},"rs7970695",27]
["ENSG00000157895","C12orf43",12,121440225,121454305,-1,"protein_coding",64897,"C12orf43",{"v":2.5600625299979e-07,"d":"2.56E-07"},0.963740862,15,8.653,36,{"v":3.71081e-18,"d":"3.71E-18"},{"v":4.17435e-40,"d":"4.17E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","No","NA",{"v":1.6e-09,"d":"1.60E-09"},"rs7970695",27]
["ENSG00000135114","OASL",12,121458095,121477045,-1,"protein_coding",8638,"OASL",{"v":5.07293522290638e-12,"d":"5.07E-12"},0.332934746,2,1.481,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.8E-5,"d":"2.80E-05"},"rs7970695",27]
["ENSG00000135124","P2RX4",12,121647660,121671909,1,"protein_coding",5025,"P2RX4",{"v":2.36800653754896e-09,"d":"2.37E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":8.1e-08,"d":"8.10E-08"},"rs7970695",27]
["ENSG00000139714","MORN3",12,122089024,122110537,-1,"protein_coding",283385,"MORN3",{"v":1.82555353991208e-06,"d":"1.83E-06"},1.089669662,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000139725","RHOF",12,122215664,122241309,-1,"protein_coding",54509,"RHOF",0.00520736033592633,-0.238094128,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000139718","SETD1B",12,122242086,122270562,1,"protein_coding",23067,"SETD1B",0.0224563158915498,-1.50972803,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.4e-08,"d":"8.40E-08"},"rs7970695",27]
["ENSG00000186009","ATP4B",13,114303119,114312501,-1,"protein_coding",496,"ATP4B",{"v":1.84084732787283e-05,"d":"1.84E-05"},-0.325434206,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-08,"d":"2.30E-08"},"rs6602911",28]
["ENSG00000184497","TMEM255B",13,114462216,114514926,1,"protein_coding",348013,"TMEM255B",{"v":3.85360358148072e-10,"d":"3.85E-10"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-08,"d":"2.30E-08"},"rs6602911",28]
["ENSG00000183087","GAS6",13,114523522,114567046,-1,"protein_coding",2621,"GAS6",0.333438602414211,"NA",21,8.523,19,{"v":2.0962e-12,"d":"2.10E-12"},{"v":8.39817e-08,"d":"8.40E-08"},"GTEx/v8/Liver","-","No","NA",{"v":2.3e-08,"d":"2.30E-08"},"rs6602911",28]
["ENSG00000130177","CDC16",13,115000362,115038198,1,"protein_coding",8881,"CDC16",0.952255349904704,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-08,"d":"2.30E-08"},"rs6602911",28]
["ENSG00000198824","CHAMP1",13,115079988,115092796,1,"protein_coding",283489,"CHAMP1",0.985193951059278,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-08,"d":"2.30E-08"},"rs6602911",28]
["ENSG00000178997","EXD1",15,41474923,41522941,-1,"protein_coding",161829,"EXD1",{"v":2.0333200373386e-13,"d":"2.03E-13"},-0.270387485,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":8.5e-13,"d":"8.50E-13"},"rs28364531:rs143875230",29]
["ENSG00000187446","CHP1",15,41523037,41574043,1,"protein_coding",11261,"CHP1",0.228123191828265,-1.39722731,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":8.5e-13,"d":"8.50E-13"},"rs28364531:rs143875230",29]
["ENSG00000104147","OIP5",15,41601466,41624819,-1,"protein_coding",11339,"OIP5",{"v":1.53697409243863E-8,"d":"1.54E-08"},0.035959624,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5e-08,"d":"1.50E-08"},"rs28364531",29]
["ENSG00000137804","NUSAP1",15,41624892,41673248,1,"protein_coding",51203,"NUSAP1",0.00510251786113418,0.133430873,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5e-08,"d":"1.50E-08"},"rs28364531",29]
["ENSG00000137825","ITPKA",15,41785591,41795747,1,"protein_coding",3706,"ITPKA",0.821022368669755,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.1E-9,"d":"3.10E-09"},"rs28364531",29]
["ENSG00000137802","MAPKBP1",15,42066632,42120053,1,"protein_coding",23005,"MAPKBP1",0.999024889896837,-0.30153116,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5e-08,"d":"1.50E-08"},"rs28364531",29]
["ENSG00000268632","AC073657.1",15,42073346,42076229,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5e-08,"d":"1.50E-08"},"rs28364531",29]
["ENSG00000137877","SPTBN5",15,42140345,42186275,-1,"protein_coding",51332,"SPTBN5",{"v":1.09010380481407e-70,"d":"1.09E-70"},0.338139096,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":8.3e-18,"d":"8.30E-18"},"rs7167976;rs690170:rs690170:rs139974673:rs28364531",29]
["ENSG00000103966","EHD4",15,42190950,42264776,-1,"protein_coding",30844,"EHD4",0.00149680577068074,0.643877563,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs28364531",29]
["ENSG00000188089","PLA2G4E",15,42273780,42343388,-1,"protein_coding",123745,"PLA2G4E",{"v":2.28331485083454e-06,"d":"2.28E-06"},1.164461603,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.8e-11,"d":"1.80E-11"},"rs28364531:rs143875230",29]
["ENSG00000159337","PLA2G4D",15,42359207,42386752,-1,"protein_coding",283748,"PLA2G4D",{"v":6.29227608353161e-10,"d":"6.29E-10"},-0.72281238,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000168907","PLA2G4F",15,42433332,42448839,-1,"protein_coding",255189,"PLA2G4F",{"v":1.39975398074621E-9,"d":"1.40E-09"},-0.131699649,3,14.51,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000166887","VPS39",15,42450899,42500514,-1,"protein_coding",23339,"VPS39",0.000738264521045905,-1.396006778,2,14.51,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000103978","TMEM87A",15,42502730,42565861,-1,"protein_coding",25963,"TMEM87A",0.785702662224374,-0.657842159,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000214013","GANC",15,42565431,42645864,1,"protein_coding",2595,"GANC",{"v":2.37915434464825e-21,"d":"2.38E-21"},0.445176713,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000092529","CAPN3",15,42640301,42704516,1,"protein_coding",825,"CAPN3",{"v":9.73741042585956e-09,"d":"9.74E-09"},0.246318186,5,7.255,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000103994","ZNF106",15,42705021,42783321,-1,"protein_coding",64397,"ZNF106",0.219458519047887,0.94150572,2,7.255,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-9,"d":"2.40E-09"},"rs28364531",29]
["ENSG00000092531","SNAP23",15,42783431,42837547,1,"protein_coding",8773,"SNAP23",0.826507888875192,-0.735183351,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs28364531",29]
["ENSG00000180979","LRRC57",15,42834720,42841000,-1,"protein_coding",255252,"LRRC57",0.000686890124895267,0.184144186,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.5E-15,"d":"2.50E-15"},"rs28364531:rs143875230:rs117578063",29]
["ENSG00000137814","HAUS2",15,42841008,42862192,1,"protein_coding",55142,"HAUS2",0.00140043242000112,1.070615049,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.5E-15,"d":"2.50E-15"},"rs28364531:rs143875230:rs117578063",29]
["ENSG00000159433","STARD9",15,42867857,43013179,1,"protein_coding",57519,"STARD9","NA",0.425546274,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.5E-15,"d":"2.50E-15"},"rs28364531:rs143875230:rs117578063",29]
["ENSG00000140326","CDAN1",15,43015757,43029324,-1,"protein_coding",146059,"CDAN1",0.928144193175439,-0.233969905,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-18,"d":"3.10E-18"},"rs7167976;rs690170:rs690170:rs139974673:rs28364531:rs143875230:rs117578063",29]
["ENSG00000128881","TTBK2",15,43030932,43213007,-1,"protein_coding",146057,"TTBK2",0.996929374509573,-1.411963872,1,0.793,137,{"v":6.03493E-6,"d":"6.03E-06"},0.000554333,"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5E-15,"d":"2.50E-15"},"rs143875230;rs690170;rs7167976;rs690170:rs690170:rs143875230:rs28364531:rs117578063",29]
["ENSG00000159459","UBR1",15,43235095,43398311,-1,"protein_coding",197131,"UBR1",0.319889980799525,-0.76152587,2,7.343,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1e-18,"d":"3.10E-18"},"rs143875230;rs28364531:rs143875230:rs117578063:rs7167976;rs690170:rs690170:rs139974673",29]
["ENSG00000166947","EPB42",15,43398423,43513481,-1,"protein_coding",2038,"EPB42",{"v":1.56180488450141e-07,"d":"1.56E-07"},-0.595710426,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-19,"d":"4.60E-19"},"rs117578063:rs7167976;rs690170:rs1561458:rs7167976;rs566555:rs566555:rs139974673:rs690170:rs28364531:rs143875230:rs45617141",29]
["ENSG00000137842","TMEM62",15,43415477,43477344,1,"protein_coding",80021,"TMEM62",{"v":5.98675580191077e-08,"d":"5.99E-08"},-0.788996062,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.4e-05,"d":"4.40E-05"},"rs7167976;rs690170:rs690170",29]
["ENSG00000166946","CCNDBP1",15,43477316,43487396,1,"protein_coding",23582,"CCNDBP1",0.0372725464260417,-0.664989272,0,0,131,{"v":3.59265e-05,"d":"3.59E-05"},{"v":1.8316E-6,"d":"1.83E-06"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.5e-13,"d":"8.50E-13"},"rs7167976;rs690170;rs566555;rs143875230:rs117578063",29]
["ENSG00000104055","TGM5",15,43524793,43559055,-1,"protein_coding",9333,"TGM5",{"v":5.36528605073887E-16,"d":"5.37E-16"},-0.136771588,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-19,"d":"4.60E-19"},"rs28364531:rs117578063:rs143875230:rs45617141:rs690170:rs7167976;rs690170:rs139974673",29]
["ENSG00000159495","TGM7",15,43568478,43594453,-1,"protein_coding",116179,"TGM7",{"v":6.34381866870598e-10,"d":"6.34E-10"},-0.076725641,1,1.292,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1e-18,"d":"3.10E-18"},"rs117578063;rs143875230:rs7167976;rs690170:rs690170:rs139974673",29]
["ENSG00000168806","LCMT2",15,43619974,43622803,-1,"protein_coding",9836,"LCMT2",{"v":7.26615001081782e-08,"d":"7.27E-08"},-0.138073747,3,8.184,491,{"v":1.25752e-13,"d":"1.26E-13"},{"v":2.53724e-11,"d":"2.54E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.2e-20,"d":"3.20E-20"},"rs45617141;rs690170;rs28364531;rs143875230;rs117578063;rs7167976;rs139974673;rs145326144;rs566555;rs1561458;15:44277180_GA_G;rs690170:rs690170:rs139974673",29]
["ENSG00000168803","ADAL",15,43622872,43646096,1,"protein_coding",161823,"ADAL",{"v":8.52495696643507e-09,"d":"8.52E-09"},0.367079509,22,11.82,491,{"v":9.208e-86,"d":"9.21E-86"},{"v":1.77353E-83,"d":"1.77E-83"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.2e-20,"d":"3.20E-20"},"rs45617141;rs690170;rs7167976;rs28364531;rs143875230;rs117578063;rs139974673;rs145326144;rs566555;rs1561458;15:44277180_GA_G;rs690170:rs690170:rs139974673",29]
["ENSG00000140265","ZSCAN29",15,43650370,43663223,-1,"protein_coding",146050,"ZSCAN29",{"v":2.29379256843049e-06,"d":"2.29E-06"},-1.044556633,25,16.12,154,{"v":2.42113E-6,"d":"2.42E-06"},{"v":3.05805e-18,"d":"3.06E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-19,"d":"4.60E-19"},"rs7167976;rs690170;rs566555;rs690170:rs117578063:rs45617141:rs690170:rs139974673:rs143875230",29]
["ENSG00000137822","TUBGCP4",15,43661419,43699293,1,"protein_coding",27229,"TUBGCP4",0.00528348188155799,-0.843870096,39,16.12,1,0.000487895,0.00733899,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-19,"d":"4.60E-19"},"rs690170;rs7167976;rs139974673;rs690170:rs117578063:rs45617141:rs690170:rs139974673:rs143875230",29]
["ENSG00000067369","TP53BP1",15,43699407,43802926,-1,"protein_coding",7158,"TP53BP1",0.999855964238627,-0.588436209,98,19.14,482,{"v":3.49072e-24,"d":"3.49E-24"},{"v":1.19394E-18,"d":"1.19E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-20,"d":"3.20E-20"},"rs690170;rs7167976;rs139974673;rs117578063;rs145326144;rs566555;rs1561458;15:44277180_GA_G;rs690170:rs690170:rs139974673:rs139974673",29]
["ENSG00000166963","MAP1A",15,43803156,43823818,1,"protein_coding",4130,"MAP1A",0.999688997602479,-0.820833828,17,19.98,389,{"v":4.34252e-07,"d":"4.34E-07"},0.000567018,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-20,"d":"3.20E-20"},"rs690170;rs7167976;rs139974673;rs566555;rs1561458;15:44277180_GA_G;rs690170:rs690170:rs139974673:rs139974673;rs145326144",29]
["ENSG00000168781","PPIP5K1",15,43825660,43882430,-1,"protein_coding",9677,"PPIP5K1",0.102604913232572,-0.983223441,23,19.98,5,1.15723E-4,0.0478915,"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops",{"v":1e-18,"d":"1.00E-18"},"rs7167976;rs690170;rs139974673;rs45617141;rs690170:rs7167976",29]
["ENSG00000237289","CKMT1B",15,43885252,43897099,1,"protein_coding",1159,"CKMT1B",0.0732106469813755,-0.423830879,19,19.4,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.1E-9,"d":"3.10E-09"},"rs690170;rs7167976;rs690170:rs7167976",29]
["ENSG00000242866","STRC",15,43891596,44010458,-1,"protein_coding",161497,"STRC",0.00532184460844672,-0.331251676,82,19.4,2,{"v":8.06122e-05,"d":"8.06E-05"},{"v":4.76889e-05,"d":"4.77E-05"},"GTEx/v8/Liver","+","Yes","Promoter_anchored_loops",{"v":3.2e-20,"d":"3.20E-20"},"rs690170;rs7167976;rs139974673;rs145326144;rs1561458;rs45617141;rs690170:rs7167976;rs690170:rs139974673:rs139974673;rs145326144:rs145326144:rs143875230:rs1561458;15:44277180_GA_G",29]
["ENSG00000166762","CATSPER2",15,43920701,43960316,-1,"protein_coding",117155,"CATSPER2",{"v":3.0443890998245e-05,"d":"3.04E-05"},"NA",44,12.63,316,{"v":4.86177e-15,"d":"4.86E-15"},{"v":8.90303e-11,"d":"8.90E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":4.9e-18,"d":"4.90E-18"},"rs7167976;rs690170;rs139974673;rs145326144;rs566555;rs45617141;rs690170:rs7167976",29]
["ENSG00000223572","CKMT1A",15,43985084,43991420,1,"protein_coding",548596,"CKMT1A",0.0141217929367762,-0.865448785,9,9.716,328,{"v":3.19085e-15,"d":"3.19E-15"},{"v":1.04753E-10,"d":"1.05E-10"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":3.2e-20,"d":"3.20E-20"},"rs7167976;rs690170;rs143875230;rs117578063;rs139974673;rs145326144;rs566555;rs139974673:rs7167976;rs690170:rs690170:rs1561458:rs7167976;rs566555:rs1561458;15:44277180_GA_G",29]
["ENSG00000167004","PDIA3",15,44038590,44065477,1,"protein_coding",2923,"PDIA3",0.959251419181895,-0.294235316,28,18.3,5,{"v":2.88624E-5,"d":"2.89E-05"},1.55857E-3,"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":3.1e-18,"d":"3.10E-18"},"rs7167976;rs690170;rs45617141;rs139974673;rs690170:rs7167976;rs690170:rs145326144",29]
["ENSG00000128886","ELL3",15,44064798,44069741,-1,"protein_coding",80237,"ELL3",{"v":3.17480785408243e-06,"d":"3.17E-06"},-0.742052013,16,18.3,439,{"v":1.85612E-13,"d":"1.86E-13"},{"v":2.53513e-09,"d":"2.54E-09"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-20,"d":"3.20E-20"},"rs7167976;rs690170;rs45617141;rs139974673;rs145326144;rs566555;rs1561458;15:44277180_GA_G;rs690170:rs690170:rs139974673:rs566555:rs7167976;rs566555:rs1561458:rs1561458;15:44277180_GA_G:rs139974673;rs145326144:rs57800679:rs145326144",29]
["ENSG00000262560","RP11-296A16.1",15,44064815,44091331,-1,"protein_coding","NA","NA","NA","NA",29,23.2,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":9.2e-07,"d":"9.20E-07"},"rs7167976;rs690170",29]
["ENSG00000140264","SERF2",15,44069285,44094787,1,"protein_coding",10169,"SERF2",0.138975962472976,-0.560226742,32,23.2,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-19,"d":"4.60E-19"},"rs7167976;rs690170;rs690170:rs690170:rs139974673:rs566555:rs7167976;rs566555:rs1561458:rs1561458;15:44277180_GA_G:rs139974673;rs145326144:rs57800679:rs145326144",29]
["ENSG00000268488","AC018512.1",15,44075041,44075231,-1,"protein_coding","NA","NA","NA","NA",15,10.34,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-19,"d":"4.60E-19"},"rs7167976;rs690170;rs566555:rs1561458:rs1561458;15:44277180_GA_G:rs7167976;rs690170:rs690170:rs139974673:rs139974673;rs145326144:rs145326144",29]
["ENSG00000184716","SERINC4",15,44086360,44092419,-1,"protein_coding",619189,"SERINC4",0.0107594286376223,-0.978460908,17,23.2,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":9.2e-07,"d":"9.20E-07"},"rs7167976;rs690170",29]
["ENSG00000242028","HYPK",15,44088340,44095241,1,"protein_coding",25764,"HYPK",0.021030750002461,-0.443035584,18,23.2,97,{"v":2.42065e-05,"d":"2.42E-05"},0.0100367,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":8.3e-18,"d":"8.30E-18"},"rs7167976;rs690170;rs690170:rs690170:rs139974673",29]
["ENSG00000140259","MFAP1",15,44096690,44117000,-1,"protein_coding",4236,"MFAP1",0.986958816915287,-0.653267663,32,23.2,0,"NA","NA","NA","NA","No","NA",{"v":9.2e-07,"d":"9.20E-07"},"rs7167976;rs690170",29]
["ENSG00000092470","WDR76",15,44119161,44160617,1,"protein_coding",79968,"WDR76",0.00230519074795657,-1.291871788,51,18.68,0,"NA","NA","NA","NA","No","NA",{"v":1.9E-6,"d":"1.90E-06"},"rs7167976;rs690170;rs566555",29]
["ENSG00000171877","FRMD5",15,44162962,44487450,-1,"protein_coding",84978,"FRMD5",0.991843164486017,-1.541636281,209,18.68,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.9e-18,"d":"4.90E-18"},"rs7167976;rs690170;rs544955246;rs566555;rs1561458;15:44277180_GA_G;rs139974673;rs145326144;rs45617141;rs57800679;rs690170:rs139974673;rs145326144:rs690170:rs7167976:rs544955246:rs566555:rs7167976;rs566555:rs1561458:rs1561458;15:44277180_GA_G:rs45617141:15:44277180_GA_G:rs57800679:rs145326144",29]
["ENSG00000166734","CASC4",15,44580927,44707956,1,"protein_coding",113201,"CASC4",0.000967729828290193,-1.716637278,2,16.39,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-15,"d":"1.30E-15"},"rs139974673;rs145326144;rs566555:rs7167976;rs566555:rs145326144:rs7167976;rs690170:rs7167976:rs544955246:rs1561458:rs1561458;15:44277180_GA_G:rs139974673;rs145326144:15:44277180_GA_G:rs57800679:rs45617141",29]
["ENSG00000137770","CTDSPL2",15,44719432,44821236,1,"protein_coding",51496,"CTDSPL2",0.995978213604988,-2.709896183,1,0.026,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-15,"d":"2.90E-15"},"rs145326144;rs566555:rs7167976;rs566555:rs145326144:rs139974673;rs145326144:rs7167976;rs690170:rs7167976:rs544955246:rs1561458:rs1561458;15:44277180_GA_G:rs45617141:15:44277180_GA_G:rs57800679",29]
["ENSG00000104131","EIF3J",15,44829255,44855227,1,"protein_coding",8669,"EIF3J",0.859084260110388,-0.525168639,1,4.009,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-15,"d":"1.30E-15"},"rs145326144;rs7167976:rs7167976;rs690170:rs139974673;rs145326144:rs566555:rs7167976;rs566555:rs1561458:rs1561458;15:44277180_GA_G:rs57800679:rs544955246:rs145326144:rs45617141:15:44277180_GA_G",29]
["ENSG00000104133","SPG11",15,44854894,44955876,-1,"protein_coding",80208,"SPG11",{"v":2.91203449273578E-22,"d":"2.91E-22"},-0.610414505,5,11.07,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":6.9e-13,"d":"6.90E-13"},"rs139974673;rs145326144;rs566555:rs7167976;rs566555",29]
["ENSG00000229474","PATL2",15,44957930,45003514,-1,"protein_coding",197135,"PATL2",0.0677100893702347,0.105561141,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1E-13,"d":"1.10E-13"},"rs139974673;rs145326144:rs145326144:rs7167976;rs690170:rs7167976:rs544955246:rs566555:rs7167976;rs566555",29]
["ENSG00000166710","B2M",15,45003675,45011075,1,"protein_coding",567,"B2M",0.856561948026764,0.154210813,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1E-13,"d":"1.10E-13"},"rs139974673;rs145326144:rs145326144:rs7167976;rs690170:rs7167976:rs544955246:rs566555:rs7167976;rs566555",29]
["ENSG00000185880","TRIM69",15,45021186,45060027,1,"protein_coding",140691,"TRIM69",{"v":1.96411504084879e-10,"d":"1.96E-10"},0.017868058,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1E-13,"d":"1.10E-13"},"rs1561458:rs566555:rs1561458;15:44277180_GA_G:rs139974673;rs145326144:rs145326144:rs7167976;rs690170:rs7167976:rs544955246:rs7167976;rs566555",29]
["ENSG00000140263","SORD",15,45315302,45369383,1,"protein_coding",6652,"SORD",4.34794621162012E-3,-0.211294181,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.5e-14,"d":"3.50E-14"},"rs1561458;15:44277180_GA_G:rs139974673;rs145326144",29]
["ENSG00000171763","SPATA5L1",15,45694529,45713617,1,"protein_coding",79029,"SPATA5L1",{"v":4.79851298392042e-11,"d":"4.80E-11"},0.36512828,0,0,1,{"v":6.07831e-05,"d":"6.08E-05"},{"v":1.38486e-40,"d":"1.38E-40"},"GTEx/v8/Adipose_Subcutaneous","-","No","NA",{"v":2.9e-10,"d":"2.90E-10"},"rs145326144",29]
["ENSG00000137871","ZNF280D",15,56922379,57210769,-1,"protein_coding",54816,"ZNF280D",0.820128047448904,-0.120447238,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.2E-35,"d":"4.20E-35"},"rs28607776;rs55966152:rs55966152:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs28607776:rs1560390:rs35717353:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140",30]
["ENSG00000140262","TCF12",15,57210821,57591479,1,"protein_coding",6938,"TCF12",0.973899934245985,-0.962372862,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.2E-35,"d":"4.20E-35"},"rs28607776;rs55966152:rs55966152:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs28607776:rs1560390:rs35717353:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140",30]
["ENSG00000128918","ALDH1A2",15,58245622,58790065,-1,"protein_coding",8854,"ALDH1A2",0.516630055977224,1.671453522,490,17.78,62,{"v":1.74747E-9,"d":"1.75E-09"},{"v":4.07162e-05,"d":"4.07E-05"},"GTEx/v8/Liver","-","Yes","Adult_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-157,"d":"3.30E-157"},"rs117266250;rs35717353;rs55966152;rs72739122;rs34663616;rs28607776;15:58561679_GAAAAAA_G;rs1560390;rs149299515;rs938509;rs554369334;rs12917140;rs413458;rs1711046;rs52971;rs56195705;rs117459981;rs72739189;rs72740828;rs11853431;rs185221561;rs12907378;rs74018729;rs8037865;rs445093;rs11071373;rs1560389;rs182006;rs77703135;rs59739041;rs479084;rs185481;rs147468898;rs145347194;rs200743386;rs4775039;rs10152355;rs139071476;rs1601933;rs261290;rs1601935;rs8042174;rs723967;rs117901517;rs576650681;15:58682029_TGAA_T;rs11853674;rs34718390;rs17240832;rs12708454;rs12916206;rs12438999;rs75663614;rs11071380;rs118078695;rs78893833;rs60315394;rs74019428;rs13329672;rs62000866;rs11858279;rs35300429;rs402465;rs72740858;rs62000869;rs8026082;rs792902;rs515081;rs396198;rs375372;rs6494005;rs261341;15:58719759_CT_C;rs17190510;15:58722073_CA_C;rs1077835;rs35511894;rs11632618;rs17269250;rs72740877;rs73420594;rs75354047;rs59999923;rs261336;rs567838;rs35138338;rs936960;rs79787170;rs10518976;rs59752567;rs79126702;rs74016195;rs17190510:rs6494005:15:58722073_CA_C:rs1077835:rs35511894:rs11632618:rs1077835;15:58719759_CT_C:rs17269250:rs72740877:rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs72740828:rs11853431:rs185221561:rs12907378:rs74018729:rs8037865:rs445093:rs11071373:rs445093;rs1560389:rs1560389:rs182006:rs77703135;rs59739041:rs59739041:rs479084:rs185481;rs479084:rs185481:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs139071476:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs17240832:rs723967;rs12438999:rs75663614:rs723967;rs11071380:rs118078695:rs17240832:rs78893833:rs723967:rs11853674;rs60315394:rs74019428:rs13329672;rs12708454:rs723967;rs11071380:rs11853674;rs60315394:rs34718390;rs62000866:rs60315394:rs13329672:rs13329672;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs72740858:rs60315394;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs60315394;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs396198:rs375372:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs73420594:rs1077835;rs261341:rs75354047:rs261341:rs59999923:rs1077835;rs261336:rs567838:rs261336:rs35138338:rs936960:rs79787170:rs10518976",30]
["ENSG00000103569","AQP9",15,58430368,58478110,1,"protein_coding",366,"AQP9",0.446614670928057,1.792505109,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway",{"v":5.6e-12,"d":"5.60E-12"},"rs72739189",30]
["ENSG00000166035","LIPC",15,58702768,58861151,1,"protein_coding",3990,"LIPC",1.71127202456162E-4,0.201437992,172,14.94,66,{"v":2.56012e-10,"d":"2.56E-10"},{"v":1.99668E-10,"d":"2.00E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Aorta:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.3E-157,"d":"3.30E-157"},"rs11853674;rs60315394;rs17240832;15:58682029_TGAA_T;rs723967;rs13329672;rs12708454;rs12438999;rs11071380;rs34718390;rs62000866;rs75663614;rs11858279;rs35300429;rs402465;rs72740858;rs62000869;rs12916206;rs77703135;rs8026082;rs792902;rs515081;rs396198;rs375372;rs6494005;rs261341;15:58719759_CT_C;rs17190510;15:58722073_CA_C;rs1077835;rs35511894;rs11632618;rs17269250;rs72740877;rs73420594;rs75354047;rs59999923;rs261336;rs567838;rs35138338;rs936960;rs79787170;rs10518976;rs59752567;rs79126702;rs74016195;rs261290;rs1601935;rs576650681;rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs72740828:rs74018729:rs11853431:rs8037865:rs445093:rs12907378:rs11071373:rs445093;rs1560389:rs1560389:rs182006:rs77703135;rs59739041:rs59739041:rs479084:rs185481;rs479084:rs185481:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs139071476:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs185221561:rs936960:rs79787170:rs59752567:rs79126702:rs74016195:rs10518976:rs17190510:rs6494005:15:58722073_CA_C:rs1077835:rs35511894:rs11632618:rs1077835;15:58719759_CT_C:rs17269250:rs72740877:rs73420594:rs1077835;rs261341:rs75354047:rs261341:rs59999923:rs1077835;rs261336:rs567838:rs261336:rs35138338",30]
["ENSG00000137845","ADAM10",15,58887403,59042177,-1,"protein_coding",102,"ADAM10",0.999844506827148,-1.03229948,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.3E-157,"d":"3.30E-157"},"rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs72740828:rs11853431:rs185221561:rs12907378:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs261290;rs1601935:rs78893833:rs723967:rs11853674;rs60315394:rs74019428:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs60315394:rs34718390;rs62000866:rs60315394:rs13329672:rs13329672;rs60315394;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs72740858:rs60315394;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs60315394;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs396198:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs17190510:15:58722073_CA_C:rs1077835:rs35511894:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs73420594:rs1077835;rs261341:rs75354047:rs261341:rs59999923:rs1077835;rs261336:rs567838:rs261336:rs35138338:rs936960:rs79787170:rs10518976:rs59752567:rs79126702:rs74016195:rs74018729:rs8037865:rs445093:rs11071373:rs445093;rs1560389:rs1560389:rs182006:rs77703135;rs59739041:rs59739041:rs479084:rs185481;rs479084:rs185481:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs139071476:rs1601935:rs117901517",30]
["ENSG00000128923","FAM63B",15,59063391,59154099,1,"protein_coding",54629,"FAM63B",0.189061306036796,-0.793708674,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.3E-157,"d":"3.30E-157"},"rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs72740828:rs11853431:rs185221561:rs12907378:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs261290;rs1601935:rs78893833:rs723967:rs11853674;rs60315394:rs74019428:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs60315394:rs34718390;rs62000866:rs60315394:rs13329672:rs13329672;rs60315394;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs72740858:rs60315394;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs60315394;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs396198:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs17190510:15:58722073_CA_C:rs1077835:rs35511894:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs73420594:rs1077835;rs261341:rs75354047:rs261341:rs59999923:rs1077835;rs261336:rs567838:rs261336:rs35138338:rs936960:rs79787170:rs10518976:rs59752567:rs79126702:rs74016195:rs74018729:rs8037865:rs445093:rs11071373:rs445093;rs1560389:rs1560389:rs182006:rs77703135;rs59739041:rs59739041:rs479084:rs185481;rs479084:rs185481:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs139071476:rs1601935:rs117901517",30]
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["ENSG00000157470","FAM81A",15,59664892,59815748,1,"protein_coding",145773,"FAM81A",0.487072320130673,-0.479273207,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.2E-35,"d":"4.20E-35"},"rs28607776;rs55966152:rs55966152:rs117266250:15:58561679_GAAAAAA_G:rs34663616:rs28607776:rs1560390:rs35717353:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs72739122",30]
["ENSG00000140297","GCNT3",15,59887074,59932438,1,"protein_coding",9245,"GCNT3",{"v":4.04466927083348e-09,"d":"4.04E-09"},0.663107477,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-157,"d":"3.30E-157"},"rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs261290;rs1601935:rs78893833:rs723967:rs11853674;rs60315394:rs74019428:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs60315394:rs34718390;rs62000866:rs60315394:rs13329672:rs13329672;rs60315394;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs72740858:rs60315394;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs60315394;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs396198:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs72740828:rs74018729:rs11853431:rs8037865:rs445093:rs12907378:rs11071373:rs445093;rs1560389:rs1560389:rs182006:rs77703135;rs59739041:rs59739041:rs479084:rs185481;rs479084:rs185481:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs139071476:rs1601935:rs117901517:rs17190510:15:58722073_CA_C:rs1077835:rs35511894:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs73420594:rs1077835;rs261341:rs75354047:rs261341:rs59999923:rs1077835;rs261336:rs567838:rs261336:rs35138338:rs936960:rs79787170:rs10518976:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs185221561:rs59752567:rs79126702:rs74016195",30]
["ENSG00000140307","GTF2A2",15,59930261,59949740,-1,"protein_coding",2958,"GTF2A2",0.386341515138839,0.898900449,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-157,"d":"3.30E-157"},"rs72740828:rs74018729:rs11853431:rs8037865:rs445093:rs12907378:rs11071373:rs445093;rs1560389:rs1560389:rs182006:rs77703135;rs59739041:rs59739041:rs479084:rs185481;rs479084:rs185481:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs139071476:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs75663614:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs78893833:rs723967:rs11853674;rs60315394:rs74019428:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs60315394:rs34718390;rs62000866:rs60315394:rs13329672:rs13329672;rs60315394;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs72740858:rs60315394;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs60315394;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs396198:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs185221561",30]
["ENSG00000182718","ANXA2",15,60639333,60695082,-1,"protein_coding",302,"ANXA2",0.00984346288196249,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-157,"d":"4.30E-157"},"rs117266250:rs35717353:rs55966152:rs72739122:rs34663616:rs28607776;rs55966152:15:58561679_GAAAAAA_G:rs28607776:rs1560390:rs149299515:rs28607776;rs1560390:rs28607776;rs55966152;rs1560390:rs938509:rs1560390;rs554369334:rs554369334:rs12917140:rs413458:rs1711046;rs52971:rs52971:rs1711046:rs56195705:rs117459981:rs72739189:rs72740828:rs11853431:rs185221561:rs12907378:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs261290;rs1601935:rs78893833:rs723967:rs11853674;rs60315394:rs74019428:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs60315394:rs34718390;rs62000866:rs60315394:rs13329672:rs13329672;rs60315394;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs72740858:rs60315394;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs60315394;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs396198:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs17190510:15:58722073_CA_C:rs1077835:rs35511894:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs73420594:rs1077835;rs261341:rs75354047:rs261341:rs59999923:rs1077835;rs261336:rs567838:rs261336:rs35138338:rs936960:rs79787170:rs10518976",30]
["ENSG00000184602","SNN",16,11762270,11773015,1,"protein_coding",8303,"SNN",0.0202490590604754,0.972465844,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1E-24,"d":"1.10E-24"},"rs62036306:rs559115405:rs559115405;rs147627332;16:14648291_AT_A:rs147359464:rs11646874:rs559115405;16:14648291_AT_A:rs12928399",31]
["ENSG00000153066","TXNDC11",16,11772936,11836734,-1,"protein_coding",51061,"TXNDC11",0.00317800786829343,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-25,"d":"1.10E-25"},"rs559115405;16:14648291_AT_A:rs559115405:rs559115405;rs147627332;16:14648291_AT_A:rs11646874:rs12928399:rs147359464:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342",31]
["ENSG00000171490","RSL1D1",16,11929056,11945442,-1,"protein_coding",26156,"RSL1D1",0.000364294182041933,-0.233303564,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.1e-25,"d":"1.10E-25"},"rs559115405;16:14648291_AT_A:rs34483003:rs559115405:16:14647113_TAA_T:16:14648291_AT_A:rs12928399:rs11646874:rs34936342",31]
["ENSG00000237515","SHISA9",16,12995477,13334272,1,"protein_coding",729993,"SHISA9","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-25,"d":"1.10E-25"},"rs62036306:rs559115405:rs559115405;rs147627332;16:14648291_AT_A:rs147359464:rs11646874:rs559115405;16:14648291_AT_A:rs12928399:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342",31]
["ENSG00000175595","ERCC4",16,14014014,14046202,1,"protein_coding",2072,"ERCC4",{"v":3.33157717442271e-10,"d":"3.33E-10"},1.194015475,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-26,"d":"1.50E-26"},"rs559115405;16:14648291_AT_A:rs559115405:rs12928399:rs11646874:rs147359464:rs62036306:rs559115405;rs147627332;16:14648291_AT_A:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342:rs147627332:rs9941229:rs111618101:16:14591093_CT_C:rs148585092:rs62036306;rs111618101",31]
["ENSG00000186260","MKL2",16,14165178,14360630,1,"protein_coding",57496,"MKL2",0.999938115504898,0.374779713,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-25,"d":"1.10E-25"},"rs559115405;16:14648291_AT_A:rs559115405:rs559115405;rs147627332;16:14648291_AT_A:rs11646874:rs12928399:rs147359464:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342:rs62036306:16:14591093_CT_C:rs147627332:rs9941229:rs111618101",31]
["ENSG00000140694","PARN",16,14529558,14726585,-1,"protein_coding",5073,"PARN",0.387183623172132,-0.956619677,135,14.45,6,{"v":1.31831E-6,"d":"1.32E-06"},{"v":8.00184e-05,"d":"8.00E-05"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops",{"v":1.5e-26,"d":"1.50E-26"},"rs62036306;rs559115405;rs147627332;16:14648291_AT_A;rs147359464;rs11646874;rs34483003;16:14591093_CT_C;rs12928399;16:14647113_TAA_T;rs34936342;rs148585092;rs111618101;rs55900631;rs538834547;rs140903773:rs71374758:rs11075261:rs11075261;rs56006013:rs11861982:rs56006013",31]
["ENSG00000269049","AC092291.2",16,14564842,14565054,1,"protein_coding","NA","NA","NA","NA",8,10.02,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-25,"d":"1.10E-25"},"rs559115405;16:14648291_AT_A;rs147627332;rs11646874;rs62036306:rs559115405:rs559115405;16:14648291_AT_A:rs147359464:rs11646874:rs559115405;16:14648291_AT_A:rs12928399:rs34483003:16:14647113_TAA_T:16:14648291_AT_A:rs34936342:rs147627332:rs9941229:rs111618101",31]
["ENSG00000103429","BFAR",16,14726672,14763093,1,"protein_coding",51283,"BFAR",0.00230974824450457,-0.464762609,9,9.255,28,{"v":9.84232e-08,"d":"9.84E-08"},1.14453E-4,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops",{"v":5.1e-24,"d":"5.10E-24"},"rs559115405;16:14648291_AT_A;rs34936342;rs62036306;rs111618101;rs11646874;rs11075260;rs538834547;rs140903773:rs71374758:rs11075261:rs11075261;rs56006013:rs11861982:rs56006013",31]
["ENSG00000069764","PLA2G10",16,14766405,14788526,-1,"protein_coding",8399,"PLA2G10",0.0217477326167779,-0.612986857,5,3.887,1,{"v":5.06613e-05,"d":"5.07E-05"},0.00873002,"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":1.5e-60,"d":"1.50E-60"},"rs111618101;rs34936342;rs188533455;16:14591093_CT_C;rs55900631;rs35512524;rs111618101:rs34936342:rs11644601",31]
["ENSG00000224712","NPIPA3",16,14802801,14820195,1,"protein_coding",642778,"NPIPA3","NA",-0.137549156,1,1.867,0,"NA","NA","NA","NA","No","NA",{"v":6.4e-11,"d":"6.40E-11"},"rs188533455;16:14591093_CT_C",31]
["ENSG00000254852","NPIPA2",16,14841923,14859270,1,"protein_coding",642799,"NPIPA2","NA",-0.137549156,6,2.922,58,{"v":4.75708e-10,"d":"4.76E-10"},{"v":2.41318e-09,"d":"2.41E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","No","NA",{"v":1.2E-61,"d":"1.20E-61"},"rs148585092;rs4003231;rs146651998;rs200324553;rs55900631;rs370260133;rs3198697;rs374889059;rs11644601;rs547988405;rs11075260;rs62039124;rs138689353;rs12443661;rs62036870;rs880071;rs75976347;rs11862588;rs2384934;rs35429473;rs8048552;rs199688311;rs149098976;rs572006137;rs12185145;rs222134;rs222133;16:15631215_AT_A",31]
["ENSG00000103512","NOMO1",16,14927538,14990017,1,"protein_coding",23420,"NOMO1","NA",-0.55803402,13,12.9,84,{"v":3.09949e-10,"d":"3.10E-10"},{"v":2.74226e-15,"d":"2.74E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell",{"v":7.3e-74,"d":"7.30E-74"},"rs370260133;rs572006137;rs149098976;rs538834547;rs140903773;rs71374758;rs11644601;rs3198697;rs59267950;rs374889059;rs11646874;rs2307502;rs153799;rs2519438;rs35512524;rs72789541;rs755903303;rs34955778;rs11075260;rs8054081;16:15640870_CT_C;rs559115405;rs3867518;rs11075261;rs56006013;rs12185145;rs222134;rs222133;16:15631215_AT_A;rs12443661;rs147616502;rs2384934;rs79295535;rs222133:rs774936434:rs222134:rs538834547:rs222133:rs62036870:rs62036870;rs9652608:rs147616502:rs12443661;rs147616502:rs117876551:rs62039124;rs62036870;rs880071;rs138689353;rs75976347:rs138689353:rs11862588:rs12443661:rs62039124;rs138689353:rs880071:rs796590036:rs147616502;rs79295535:rs9652608",31]
["ENSG00000183426","NPIPA1",16,15016659,15045915,1,"protein_coding",9284,"NPIPA1",0.495053838627117,-0.152307969,12,10.34,375,{"v":2.27979e-39,"d":"2.28E-39"},{"v":4.30601e-32,"d":"4.31E-32"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":7.3e-74,"d":"7.30E-74"},"rs536082326;rs562837772;rs527928577;rs6498525;rs4985171;rs8057053;rs3198697;16:15054455_GT_G;rs35429473;rs528780951;rs34483003;rs559115405;rs12928399;16:14648291_AT_A;rs34936342;rs2519438;rs59267950;rs370260133;rs149098976;rs572006137;rs538834547;rs140903773;rs374889059;rs35512524;rs547988405;rs72789541;rs755903303;rs11644601;rs8048552;rs11075260;rs199534502;rs11861982;rs11075261;rs377032889;rs3867518;rs56006013;rs199782954;rs62037794;rs199688311;rs61084260;rs140014347;rs2307502;rs153799;rs774936434;rs8053048;rs12185145;rs222134;rs222133;16:15631215_AT_A;rs1684546;rs766485929;16:15598635_TA_T;rs62039124;rs138689353;16:15640870_CT_C;rs34072053;rs62036870;rs9652608;rs12443661;rs880071;rs75976347;rs147616502;rs79295535;rs11862588;rs2384934;rs147359464;rs148664265;rs111618101;rs62037530;rs188533455;rs147627332",31]
["ENSG00000179889","PDXDC1",16,15068448,15233196,1,"protein_coding",23042,"PDXDC1",{"v":2.30260183441473e-07,"d":"2.30E-07"},-0.437005006,150,22.7,181,{"v":3.10265e-25,"d":"3.10E-25"},{"v":1.00609e-19,"d":"1.01E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs72789530;rs200575134;rs7500839;rs529360800;rs28418438;rs11645956;rs201927328;rs72789541;16:15073154_GT_G;rs7204096;rs59267950;rs35512524;rs11075248;rs148664265;rs71374758;rs371634194;rs9928601;rs111925547;16:15086706_CT_C;rs547988405;16:15090275_ATATTATATG_A;rs13335603;rs6416661;rs112284265;rs6498536;rs11645958;rs7195873;16:15106708_TA_T;16:15108063_CA_C;16:15108787_CTA_C;rs4262938;rs28412131;rs370903249;rs8057053;rs374889059;rs4985126;rs9888789;rs8059755;rs6416662;rs111640095;rs140699316;rs755903303;rs533355407;rs3198697;rs34955778;rs58636152;rs11644601;rs188533455;rs35429473;rs8048552;rs138689353;rs538834547;rs147359464;rs34483003;rs12928399;rs34936342;rs11075260;rs199534502;rs11861982;rs377032889;rs8054081;16:15414730_CTTTTTTTTTT_C;rs139110024;rs75512281;rs140014347;rs153799;rs62039124;rs572006137;rs62036870;rs880071;rs75976347;rs11862588;rs140903773;16:14591093_CT_C;rs111618101;rs55900631;rs2519438;rs199782954;rs62037530;rs149098976;rs11075261;rs3867518;rs56006013;rs1684546;rs12443661;rs147616502;rs79295535;rs8048552:rs59267950:rs35512524:rs538834547:rs528066129:rs34072053:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs72789541:rs3198697:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs1684546:rs62039124;rs138689353:rs62039124:16:15631215_AT_A:16:15640870_CT_C:16:15635759_TA_T:rs11075248:rs148664265:rs71374758:rs371634194:rs9928601:rs111925547:rs72789541;rs72789530:16:15086706_CT_C:rs547988405:16:15090275_ATATTATATG_A:rs201927328:rs13335603:rs6416661:rs112284265:rs6498536:rs11645958:rs7195873:16:15106708_TA_T:16:15108063_CA_C:16:15108787_CTA_C:rs4262938:rs28412131:rs370903249:rs8057053;rs11075248:rs374889059:rs4985126:rs9888789:rs8059755:rs62036870:rs62036870;rs9652608:rs147616502:rs12443661;rs147616502:rs796590036:rs11862588:rs147616502;rs79295535:rs9652608:rs12443661:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs774936434;rs8053048:rs12185145:rs222134;rs222133:rs774936434:rs12185145;rs222134;rs222133:rs153799:rs12185145;16:15631215_AT_A;rs222133:rs222134:rs222133:rs1684546;rs774936434:rs766485929:rs36058330:rs555987464:rs117876551;rs796590036:rs117876551:rs62039124;rs75976347:rs138689353:rs62039124;rs138689353:rs75976347:rs2384934;rs12443661:rs880071:rs2384934:rs79295535",31]
["ENSG00000157045","NTAN1",16,15131710,15149921,-1,"protein_coding",123803,"NTAN1",0.0158736622184606,"NA",55,22.7,74,{"v":2.21296e-14,"d":"2.21E-14"},{"v":7.68744e-10,"d":"7.69E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs140699316;rs72789541;rs755903303;rs533355407;rs35512524;rs59267950;rs3198697;rs34955778;rs58636152;rs11644601;rs188533455;rs199782954;rs62037530;rs35429473;rs11075260;rs11075261;rs3867518;rs56006013;rs2519438;rs199688311;rs2384934;rs111618101;rs8048552;rs528780951;rs148664265;rs117876551;rs572006137;rs149098976;rs538834547;rs140903773;rs12185145;rs147616502;rs12443661;rs79295535;rs59267950:rs374889059:rs547988405:rs148664265:rs538834547:rs35512524:rs201927328:rs72789541;rs755903303:rs72789541:rs34955778:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:rs3198697:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:16:15073154_GT_G:rs7204096:16:15640870_CT_C:rs62039124:rs62039124;rs138689353:rs34072053:rs62036870:rs117876551;rs796590036:rs62036870;rs9652608:rs147616502:rs12443661;rs147616502:rs796590036:rs11862588:rs147616502;rs79295535:rs9652608:rs12443661:rs117876551:rs62039124;rs62036870;rs880071;rs138689353;rs75976347:rs138689353:rs62039124;rs138689353:rs75976347:rs11075248:rs71374758:rs371634194:rs9928601:rs111925547:rs72789541;rs72789530:16:15086706_CT_C:16:15090275_ATATTATATG_A:rs13335603:rs6416661:rs112284265:rs6498536:rs11645958:rs7195873:16:15106708_TA_T:16:15108063_CA_C:16:15108787_CTA_C:rs4262938:rs28412131:rs370903249:rs8057053;rs11075248:rs4985126:rs9888789:rs8059755:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs1684546:16:15631215_AT_A:16:15635759_TA_T:rs880071:rs79295535",31]
["ENSG00000085721","RRN3",16,15153879,15188174,-1,"protein_coding",54700,"RRN3",0.000474580439094432,-0.668988091,26,6.506,84,{"v":9.54152e-09,"d":"9.54E-09"},{"v":8.06072e-24,"d":"8.06E-24"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":7.3e-74,"d":"7.30E-74"},"rs72789541;rs755903303;rs58636152;rs11644601;rs59267950;rs188533455;rs35429473;rs8048552;rs35512524;rs138689353;rs547988405;rs148664265;rs538834547;rs11862588;rs3198697;rs11075260;rs117876551;rs62036306;rs111618101;rs3867518;rs11075261;rs56006013;rs2519438;rs199782954;rs2384934;rs11646874;rs8053048;rs111618101:rs34936342:rs59267950:rs374889059:rs72789530:rs7500839:rs529360800:rs28418438:rs188533455:rs547988405:rs201927328:rs374889059;rs547988405:rs188533455;rs138689353:rs35512524:rs538834547",31]
["ENSG00000183793","NPIPA5",16,15457516,15474904,-1,"protein_coding",100288332,"NPIPA5",0.544994923114436,-0.083296396,10,2.863,436,{"v":2.49656E-61,"d":"2.50E-61"},{"v":1.0127E-51,"d":"1.01E-51"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":7.3e-74,"d":"7.30E-74"},"rs61084260;rs149098976;rs572006137;rs140903773;rs75512281;rs140014347;rs113735279;rs201927328;rs9941229;rs34483003;rs559115405;rs12928399;16:14648291_AT_A;rs34936342;rs111618101;rs146651998;rs59267950;rs370260133;rs538834547;rs3198697;rs374889059;rs35429473;rs35512524;rs148664265;rs547988405;rs140699316;rs72789541;rs755903303;rs11644601;rs8048552;rs188533455;rs138689353;rs11075260;rs199534502;rs11861982;rs3867518;rs11075261;rs56006013;rs377032889;rs2519438;rs199782954;rs62037794;rs199688311;rs2307502;rs153799;rs774936434;rs12185145;rs222134;rs222133;16:15631215_AT_A;rs1684546;rs62039124;16:15598635_TA_T;rs34072053;rs62036870;rs9652608;rs147616502;rs12443661;rs11862588;rs79295535;rs880071;rs75976347;rs2384934;rs147359464;16:14591093_CT_C;rs139110024;rs62037530;rs62036306;rs117876551;rs147627332;rs1684546:rs1684546;16:15598635_TA_T:16:15598635_TA_T:16:15631215_AT_A:16:15640870_CT_C:16:15635759_TA_T:rs62039124:rs12443661;rs147616502:rs62036870;rs9652608:rs796590036:rs11862588:rs147616502",31]
["ENSG00000261130","RP11-1021N1.1",16,15489611,15609205,1,"protein_coding","NA","NA","NA","NA",113,12.74,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs61084260;rs188533455;rs138689353;rs2307502;rs149098976;rs153799;rs8053048;rs774936434;rs12185145;rs222134;rs222133;16:15631215_AT_A;rs538834547;rs1684546;rs766485929;rs36058330;16:15598635_TA_T;rs555987464;rs62039124;rs59267950:rs374889059:rs11862588:rs62039124;rs880071;rs138689353:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs1684546:rs62039124;rs138689353:rs62039124:16:15631215_AT_A:16:15640870_CT_C:16:15635759_TA_T:rs75976347:rs12443661;rs147616502:rs62039124;rs62036870;rs75976347:rs147616502;rs79295535:rs880071:rs79295535:rs34072053:rs62036870:rs117876551;rs796590036:rs62036870;rs9652608:rs147616502:rs796590036:rs9652608:rs12443661:rs117876551:rs138689353:rs199782954:rs62037530:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:rs3198697:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:rs72789541:16:15073154_GT_G:rs7204096:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs35512524:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:rs774936434;rs8053048:rs8053048:rs12185145:rs222134;rs222133:rs774936434:rs149098976:rs12185145;rs222133:rs153799:rs12185145;rs222133:rs222134:rs538834547:rs222133:rs1684546;rs774936434:rs766485929:rs36058330:rs555987464:rs2384934;rs12443661:rs2384934",31]
["ENSG00000156968","MPV17L",16,15489611,15507125,1,"protein_coding",255027,"MPV17L",0.000500982038571006,-0.394011201,11,4.787,134,{"v":2.22013e-28,"d":"2.22E-28"},{"v":3.01833e-39,"d":"3.02E-39"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs61084260;rs188533455;rs138689353;rs2307502;rs149098976;rs153799;rs8053048;16:14591093_CT_C;rs11646874;rs528780951;rs148664265;rs139110024;rs774936434;rs12185145;rs222134;rs222133;16:15631215_AT_A;rs1684546;rs766485929;rs62039124;16:15598635_TA_T;rs62036870;rs117876551;rs796590036;rs9652608;rs880071;rs75976347;rs35429473;rs8048552;rs11862588;rs59267950:rs374889059:rs11862588:rs62039124;rs138689353:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs1684546:rs62039124;rs138689353:rs62039124:16:15631215_AT_A:16:15640870_CT_C:16:15635759_TA_T:rs75976347:rs12443661;rs147616502:rs62039124;rs75976347:rs147616502;rs79295535:rs880071:rs79295535:rs34072053:rs62036870:rs117876551;rs796590036:rs62036870;rs9652608:rs147616502:rs796590036:rs9652608:rs12443661:rs117876551:rs138689353:rs199782954:rs62037530:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:rs3198697:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:rs72789541:16:15073154_GT_G:rs7204096:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs35512524:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:rs774936434;rs8053048:rs8053048:rs12185145:rs222134;rs222133:rs774936434:rs149098976:rs12185145;rs222133:rs153799:rs12185145;rs222133:rs222134:rs538834547:rs222133:rs1684546;rs774936434:rs766485929:rs36058330:rs555987464:rs2384934;rs12443661:rs2384934",31]
["ENSG00000166780","C16orf45",16,15528152,15718885,1,"protein_coding",89927,"C16orf45",0.214680178058486,-0.633435445,172,19.19,104,{"v":1.57234e-10,"d":"1.57E-10"},{"v":1.56637E-6,"d":"1.57E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-52,"d":"5.60E-52"},"rs774936434;rs8053048;rs12185145;rs222134;rs222133;rs149098976;rs153799;16:15631215_AT_A;rs538834547;rs1684546;rs766485929;rs36058330;16:15598635_TA_T;rs555987464;rs62039124;rs138689353;16:15640870_CT_C;16:15635759_TA_T;rs34072053;rs62036870;rs117876551;rs796590036;rs9652608;rs147616502;rs12443661;rs11862588;rs79295535;rs2307502;rs9652608:rs9652608:rs12443661:rs62036870:rs147616502:rs12443661;rs147616502:rs796590036:rs11862588:rs147616502;rs79295535:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:rs3198697:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:rs72789541:16:15073154_GT_G:rs7204096:rs59267950:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs1684546:rs62039124;rs138689353:rs62039124:16:15631215_AT_A:16:15640870_CT_C:16:15635759_TA_T:rs34072053:rs117876551",31]
["ENSG00000166783","KIAA0430",16,15688243,15737023,-1,"protein_coding",9665,"KIAA0430",0.999999565958546,-1.509457287,48,19.19,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs62036870;rs9652608;rs147616502;rs12443661;rs796590036;rs11862588;rs79295535;rs117876551;rs62039124;rs880071;rs138689353;rs75976347;16:15640870_CT_C:rs62039124:rs62039124;rs138689353:rs34072053:rs62036870:rs117876551;rs796590036:rs62036870;rs9652608:rs147616502:rs12443661;rs147616502:rs796590036:rs11862588:rs147616502;rs79295535:rs9652608:rs12443661:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs35512524:rs59267950:rs72789541:rs3198697:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs1684546:rs766485929:rs36058330:rs12185145;16:15631215_AT_A;rs222134;rs222133:rs1684546;16:15598635_TA_T:rs555987464:rs12185145:16:15598635_TA_T:16:15631215_AT_A:16:15635759_TA_T:rs75976347:rs62039124;rs75976347:rs62039124;rs138689353:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:16:15073154_GT_G:rs7204096:rs11075248:rs148664265:rs71374758:rs371634194:rs9928601:rs111925547:rs72789541;rs72789530:16:15086706_CT_C:rs547988405:16:15090275_ATATTATATG_A:rs13335603:rs6416661:rs112284265:rs6498536:rs11645958:rs7195873:16:15106708_TA_T:16:15108063_CA_C:16:15108787_CTA_C:rs4262938:rs28412131:rs370903249:rs8057053;rs11075248:rs374889059:rs4985126:rs9888789:rs8059755",31]
["ENSG00000072864","NDE1",16,15737124,15820210,1,"protein_coding",54820,"NDE1",0.0471095482859516,0.252883746,60,22.5,54,{"v":7.57097e-25,"d":"7.57E-25"},{"v":2.09062e-21,"d":"2.09E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs62036870;rs9652608;rs12443661;rs147616502;rs117876551;rs62039124;rs880071;rs138689353;rs75976347;rs11862588;rs79295535;rs59267950;rs71374758;rs11644601;rs11075260;rs2384934;rs55900631;rs35512524;rs11861982;16:15640870_CT_C:rs62039124:rs62039124;rs138689353:rs34072053:rs62036870:rs117876551;rs796590036:rs62036870;rs9652608:rs147616502:rs12443661;rs147616502:rs796590036:rs11862588:rs147616502;rs79295535:rs9652608:rs12443661:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs35512524:rs59267950:rs72789541:rs3198697:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs1684546:rs766485929:rs36058330:rs12185145;16:15631215_AT_A;rs222134;rs222133:rs1684546;16:15598635_TA_T:rs555987464:rs12185145:16:15598635_TA_T:16:15631215_AT_A:16:15635759_TA_T:rs75976347:rs62039124;rs75976347:rs62039124;rs138689353:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:16:15073154_GT_G:rs7204096:rs11075248:rs148664265:rs71374758:rs371634194:rs9928601:rs111925547:rs72789541;rs72789530:16:15086706_CT_C:rs547988405:16:15090275_ATATTATATG_A:rs13335603:rs6416661:rs112284265:rs6498536:rs11645958:rs7195873:16:15106708_TA_T:16:15108063_CA_C:16:15108787_CTA_C:rs4262938:rs28412131:rs370903249:rs8057053;rs11075248:rs374889059:rs4985126:rs9888789:rs8059755",31]
["ENSG00000133392","MYH11",16,15797029,15950890,-1,"protein_coding",4629,"MYH11",0.998956488496709,-1.803748E-3,80,22.5,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs11862588;rs62039124;rs62036870;rs880071;rs138689353;rs75976347;rs12443661;rs147616502;rs79295535;rs2384934;rs117876551;rs880071:rs117876551:rs79295535:rs11862588:rs147616502;rs79295535:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:rs3198697:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:rs72789541:16:15073154_GT_G:rs7204096:rs59267950:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs35512524:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:16:15640870_CT_C:rs62039124:rs62039124;rs138689353:rs34072053:rs62036870:rs117876551;rs796590036:rs62036870;rs9652608:rs147616502:rs12443661;rs147616502:rs796590036:rs9652608:rs12443661:rs62039124;rs75976347:rs138689353:rs62039124;rs138689353:rs75976347:rs2384934;rs12443661:rs2384934:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs1684546;16:15598635_TA_T:16:15598635_TA_T:rs1684546:16:15631215_AT_A:16:15635759_TA_T",31]
["ENSG00000133393","FOPNL",16,15959577,15982482,-1,"protein_coding",123811,"FOPNL",{"v":9.46709362306996e-06,"d":"9.47E-06"},1.986607342,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.3e-74,"d":"7.30E-74"},"rs35512524:rs538834547:rs528066129:rs6416662:rs111640095:rs140699316:rs72789541;rs755903303:rs533355407:rs59267950:rs72789541:rs3198697:rs34955778:rs755903303:rs58636152:rs11644601:rs188533455:rs880071:rs117876551:rs79295535:rs11862588:rs147616502;rs79295535:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:16:15073154_GT_G:rs7204096:rs61084260:rs188533455;rs138689353:rs2307502:rs149098976:rs153799;rs2307502:rs8053048:rs12443661:rs62039124;rs880071;rs138689353:rs2384934;rs12443661:rs2384934",31]
["ENSG00000091262","ABCC6",16,16242785,16317379,-1,"protein_coding",368,"ABCC6",{"v":1.4545670403957E-6,"d":"1.45E-06"},1.25585067,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.6e-52,"d":"5.60E-52"},"rs774936434;rs8053048:rs8053048:rs12185145:rs222134;rs222133:rs774936434:rs149098976:rs12185145;rs222134;rs222133:16:15598635_TA_T:16:15631215_AT_A:16:15640870_CT_C:16:15635759_TA_T:rs62039124:rs11862588:rs12443661:rs62039124;rs880071;rs138689353:rs75976347:rs12443661;rs147616502:rs62039124;rs62036870;rs138689353;rs75976347:rs147616502;rs79295535:rs880071:rs117876551:rs79295535:rs562837772:rs527928577:rs6498525:rs4985171:rs8057053;rs4985171:rs3198697:16:15054455_GT_G:16:15054455_GT_G;rs8057053:rs8057053:rs35429473:rs528780951:16:15057016_TAA_T:rs72789530:rs200575134:rs7500839:rs529360800:rs28418438:rs11645956:rs201927328:rs72789541:16:15073154_GT_G:rs7204096:rs59267950:rs62036870:rs62036870;rs9652608:rs147616502:rs796590036:rs9652608",31]
["ENSG00000103226","NOMO3",16,16326352,16388668,1,"protein_coding",408050,"NOMO3","NA",-0.391240572,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-25,"d":"1.10E-25"},"rs188533455;rs138689353:rs61084260:rs2307502:rs149098976",31]
["ENSG00000103489","XYLT1",16,17195626,17564738,-1,"protein_coding",64131,"XYLT1",0.985159711217428,2.939790489,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.1E-24,"d":"1.10E-24"},"rs559115405;16:14648291_AT_A:rs559115405:rs559115405;rs147627332;16:14648291_AT_A:rs11646874:rs12928399:rs147359464",31]
["ENSG00000134419","RPS15A",16,18792617,18801705,-1,"protein_coding",6210,"RPS15A",0.833355704516176,-0.376607162,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.9E-13,"d":"3.90E-13"},"rs880071:rs117876551:rs79295535:rs11862588",31]
["ENSG00000260342","RP11-1035H13.3",16,18799385,18812841,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.9E-13,"d":"3.90E-13"},"rs880071:rs117876551:rs79295535:rs11862588",31]
["ENSG00000170540","ARL6IP1",16,18802991,18813000,-1,"protein_coding",23204,"ARL6IP1",0.00667568860937067,-0.374658071,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.9E-13,"d":"3.90E-13"},"rs880071:rs117876551:rs79295535:rs11862588",31]
["ENSG00000126581","BECN1",17,40962152,40985367,-1,"protein_coding",8678,"BECN1",0.998697775912791,-0.469387595,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.8E-12,"d":"1.80E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",32]
["ENSG00000131467","PSME3",17,40976402,40995774,1,"protein_coding",10197,"PSME3",0.988103823358922,-1.745302754,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.8E-12,"d":"1.80E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",32]
["ENSG00000131480","AOC2",17,40996617,41002724,1,"protein_coding",314,"AOC2",{"v":5.13940212237188e-10,"d":"5.14E-10"},0.041350631,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.8E-12,"d":"1.80E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",32]
["ENSG00000161647","MPP3",17,41878167,41910538,-1,"protein_coding",4356,"MPP3",{"v":1.99785500256477e-05,"d":"2.00E-05"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5E-10,"d":"1.50E-10"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs199500",32]
["ENSG00000180329","CCDC43",17,42750437,42767147,-1,"protein_coding",124808,"CCDC43",0.000257178261367413,-0.924707928,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.6e-12,"d":"4.60E-12"},"rs16940904;rs2732699;rs577976641;rs199460;17:44286218_CA_C;rs112557952:rs16940904;rs199460:rs16940904;rs9913081;17:44286218_CA_C:rs16940904:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904",32]
["ENSG00000161692","DBF4B",17,42785976,42829632,1,"protein_coding",80174,"DBF4B",{"v":4.43213751313207E-8,"d":"4.43E-08"},-0.507761261,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.4e-09,"d":"1.40E-09"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T",32]
["ENSG00000182963","GJC1",17,42875816,42908184,-1,"protein_coding",10052,"GJC1",0.944105282209013,-2.782988352,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.6e-12,"d":"2.60E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs9913081;17:44286218_CA_C:rs16940904;rs577976641;17:44286218_CA_C;rs112557952:rs16940904:rs16940904;rs112557952:rs16940904;rs9913081:rs16940904;rs112557952",32]
["ENSG00000131097","HIGD1B",17,42923721,42927848,1,"protein_coding",51751,"HIGD1B",2.34558353981055E-3,-0.344882798,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.4e-12,"d":"4.40E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;rs2732699:rs16940904",32]
["ENSG00000108883","EFTUD2",17,42927311,42977030,-1,"protein_coding",9343,"EFTUD2",0.999991435314757,0.211209263,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.6e-12,"d":"4.60E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs577976641;rs199460;17:44286218_CA_C;rs112557952:rs16940904;rs199460:rs16940904;rs9913081;17:44286218_CA_C:rs16940904:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904",32]
["ENSG00000167131","CCDC103",17,42976510,42982758,1,"protein_coding",388389,"CCDC103",0.00218552270508304,{"v":3.73457e-05,"d":"3.73E-05"},0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.6e-12,"d":"4.60E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs577976641;rs199460;17:44286218_CA_C;rs112557952:rs16940904;rs199460:rs16940904;rs9913081;17:44286218_CA_C:rs16940904:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904",32]
["ENSG00000214447","FAM187A",17,42977135,42982758,1,"protein_coding",100528020,"FAM187A","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.6e-12,"d":"4.60E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs577976641;rs199460;17:44286218_CA_C;rs112557952:rs16940904;rs199460:rs16940904;rs9913081;17:44286218_CA_C:rs16940904:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904",32]
["ENSG00000131095","GFAP",17,42982376,42994305,-1,"protein_coding",2670,"GFAP",{"v":2.22936756487388e-05,"d":"2.23E-05"},-0.265503436,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-12,"d":"2.30E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs112557952:rs16940904;rs577976641;17:44360154_AAG_A;17:44286218_CA_C;rs2732699:rs16940904;rs9913081;17:44286218_CA_C:rs16940904;rs9913081:rs16940904:rs16940904;rs112557952:rs201647884:rs16940904",32]
["ENSG00000172992","DCAKD",17,43100708,43138473,-1,"protein_coding",79877,"DCAKD",0.0293860851896359,0.848595011,0,0,2030,{"v":1.83107e-06,"d":"1.83E-06"},{"v":2.68979e-32,"d":"2.69E-32"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","No","NA",{"v":3.9E-13,"d":"3.90E-13"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs2732699;17:44286218_CA_C;rs112557952;17:44360154_AAG_A;rs577976641;rs9913081;rs201647884;rs199460;rs55938136;rs35076622",32]
["ENSG00000136448","NMT1",17,43128978,43186384,1,"protein_coding",4836,"NMT1",0.998500520689071,0.032447683,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.6E-9,"d":"3.60E-09"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs546735951",32]
["ENSG00000181513","ACBD4",17,43209967,43221548,1,"protein_coding",79777,"ACBD4",{"v":1.82643064951694E-5,"d":"1.83E-05"},-0.326407022,0,0,1,{"v":9.3544e-06,"d":"9.35E-06"},{"v":2.53243e-07,"d":"2.53E-07"},"GTEx/v8/Artery_Tibial","+","No","NA",{"v":1.1e-10,"d":"1.10E-10"},"rs16940904;rs35076622",32]
["ENSG00000186834","HEXIM1",17,43224684,43229468,1,"protein_coding",10614,"HEXIM1",0.944400234927573,-1.495314951,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-09,"d":"1.10E-09"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T",32]
["ENSG00000168517","HEXIM2",17,43238067,43247407,1,"protein_coding",124790,"HEXIM2",0.368236513275247,-0.798107113,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.4e-12,"d":"4.40E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs199460;rs199460:rs16940904;rs9913081:rs16940904;rs577976641;rs2732699:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904",32]
["ENSG00000184922","FMNL1",17,43298811,43324687,1,"protein_coding",752,"FMNL1",0.999687036181592,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-12,"d":"1.80E-12"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699:rs16940904;rs2732699;17:44286218_CA_C",32]
["ENSG00000184361","SPATA32",17,43331760,43339479,-1,"protein_coding",124783,"SPATA32",{"v":2.95265117999751E-5,"d":"2.95E-05"},-0.414755704,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.5e-13,"d":"6.50E-13"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;rs199460:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs9913081:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;rs577976641;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs143234563",32]
["ENSG00000159314","ARHGAP27",17,43471275,43511787,-1,"protein_coding",201176,"ARHGAP27",1.25584382196987E-3,-0.761627793,87,18.95,2603,{"v":1.38418e-06,"d":"1.38E-06"},{"v":5.78187E-11,"d":"5.78E-11"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops",{"v":5.9e-13,"d":"5.90E-13"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs2732699;rs112557952;17:44360154_AAG_A;rs577976641;rs9913081;17:44286218_CA_C;rs199460;17:44858598_CA_C;rs201647884;rs55938136;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs112557952:rs16940904:rs16940904",32]
["ENSG00000225190","PLEKHM1",17,43513266,43568115,-1,"protein_coding",9842,"PLEKHM1",0.840543209831517,-0.663068032,139,18.95,2808,{"v":2.76383e-14,"d":"2.76E-14"},{"v":3.72801E-10,"d":"3.73E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs2732699;17:44286218_CA_C;rs112557952;17:44360154_AAG_A;rs577976641;rs9913081;rs201647884;rs199460;rs55938136;rs35076622;rs199500;17:44858598_CA_C;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs55938136:rs16940904:rs16940904;rs199460:rs16940904;rs2732699:rs16940904;rs199500:rs16940904",32]
["ENSG00000120088","CRHR1",17,43699267,43913194,1,"protein_coding",1394,"CRHR1",0.792134286397601,2.038085631,931,19.39,2877,{"v":1.86977E-23,"d":"1.87E-23"},{"v":2.70499e-18,"d":"2.70E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs2732699;rs577976641;17:44286218_CA_C;rs112557952;rs9913081;rs199460;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;17:44360154_AAG_A;rs201647884;rs199500;17:44858598_CA_C;rs56755526;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904;rs9913081:rs16940904;rs112557952:rs16940904:rs16940904;rs199460:rs199726619:rs16940904;rs199460:rs16940904;rs2732699:rs16940904;rs112557952:rs9913081:rs16940904;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs16940904;rs112557952:rs2732699:rs2696531:rs16940904",32]
["ENSG00000185294","SPPL2C",17,43922256,43924438,1,"protein_coding",162540,"SPPL2C",{"v":2.29524703916312e-05,"d":"2.30E-05"},0.187394842,120,23.5,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C;rs112557952;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs112557952:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs2732699:rs16940904;rs199460:rs16940904;rs546608798:rs16940904;rs56755526;rs199500:rs16940904;17:44858598_CA_C;rs9913081:rs16940904;17:44286218_CA_C:rs55938136:rs16940904;rs577976641;rs35076622:rs16940904;rs199460:rs540421791:rs16940904;17:44360154_AAG_A;rs112557952:rs369541018:rs16940904;rs112557952:rs112557952:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs16940904;rs112557952:rs2732699:rs2696531:17:44360154_AAG_A:rs16940904;rs199500:rs71363586:rs16940904;rs199460:rs375112071:rs546608798",32]
["ENSG00000186868","MAPT",17,43971748,44105700,1,"protein_coding",4137,"MAPT",{"v":4.68264962282433e-05,"d":"4.68E-05"},2.01024275,786,26.8,2885,{"v":1.31245E-17,"d":"1.31E-17"},{"v":4.84413e-68,"d":"4.84E-68"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C;rs112557952;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs201647884;rs577976641;rs55938136;rs199500;17:44858598_CA_C;17:44360154_AAG_A;rs35076622;rs56755526;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs2732699:rs16940904;rs199460:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs112557952:rs9913081:rs16940904;17:44617964_TA_T;rs112557952:17:44286218_CA_C:rs16940904;rs199500:rs16940904;rs9913081:rs55938136:rs16940904;rs112557952:rs143234563",32]
["ENSG00000256762","STH",17,44076616,44077060,1,"protein_coding",246744,"STH",0.00444466614164462,0.274193181,95,19.15,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C;17:44286218_CA_C:rs16940904;rs577976641;rs112557952:rs16940904;rs112557952:rs16940904:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs9913081:rs16940904;rs199460:rs199726619:rs16940904;rs112557952;rs199500:rs16940904;rs199460:rs16940904;17:44617964_TA_T;rs2732699:rs16940904;rs112557952:17:44286218_CA_C:rs16940904;rs112557952:rs143234563:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs112557952:rs9913081:rs16940904;rs56755526;rs199460:rs369541018:rs112557952:rs16940904;17:44286218_CA_C:rs55938136:rs16940904;rs546735951;rs35076622:rs540421791:rs16940904;rs112557952:rs2732699:rs2696531:rs16940904;rs199500:17:44858598_CA_C:rs16940904;rs199500:rs199500:17:44360154_AAG_A:rs16940904;rs199500:rs71363586:rs16940904;rs199460:rs375112071:rs546608798:rs16940904;rs546608798",32]
["ENSG00000120071","KANSL1",17,44107282,44302733,-1,"protein_coding",284058,"KANSL1",0.999733505943003,0.058945245,1070,26.4,2878,{"v":6.14241e-12,"d":"6.14E-12"},{"v":6.72547e-40,"d":"6.73E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:GM12878:Mesenchymal_Stem_Cell",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C;rs112557952;rs540421791;rs199500;rs577976641;17:44360154_AAG_A;17:44858598_CA_C;rs369541018;17:44617964_TA_T;rs143234563;rs199726619;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs201647884;rs55938136;rs35076622;rs56755526;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs112557952:rs16940904;rs9913081:rs16940904;rs2732699:rs16940904;rs199460:rs16940904;rs112557952:17:44286218_CA_C:rs16940904;rs199500:rs16940904;rs199500:rs199500:rs16940904;rs199460:rs540421791:rs16940904;rs112557952:rs143234563",32]
["ENSG00000228696","ARL17B",17,44352150,44439130,-1,"protein_coding",100506084,"ARL17B","NA",-0.428243465,302,16.76,4,{"v":4.81655e-07,"d":"4.82E-07"},{"v":7.67102e-25,"d":"7.67E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":2.3e-12,"d":"2.30E-12"},"rs16940904;rs2732699;rs199460;rs577976641;17:44286218_CA_C;rs112557952;17:44360154_AAG_A;17:44858598_CA_C;rs199500;rs9913081;rs2696531;rs71363586;rs375112071;rs546608798;rs112557952:rs16940904;rs199500:rs16940904;rs199460:rs16940904;rs112557952:rs2732699:rs16940904;rs112557952:rs2696531:rs16940904",32]
["ENSG00000176681","LRRC37A",17,44370099,44415160,1,"protein_coding",9884,"LRRC37A",0.890487355591061,"NA",78,16.76,2885,{"v":7.36791e-46,"d":"7.37E-46"},{"v":1.19942E-67,"d":"1.20E-67"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","EP_links_oneway:Promoter_anchored_loops:GM12878:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2E-13,"d":"3.20E-13"},"17:44360154_AAG_A;rs16940904;rs2732699;rs577976641;rs199460;rs112557952;17:44858598_CA_C;rs199500;17:44286218_CA_C;rs71363586;rs9913081;rs375112071;rs546608798;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs201647884;rs55938136;rs35076622;rs56755526;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs199460:rs16940904;rs112557952:rs16940904:rs16940904;rs2732699:rs16940904;rs112557952:rs369541018:rs16940904;rs199500:rs16940904;rs9913081:rs16940904;rs112557952:rs201647884:rs16940904;rs112557952:rs112557952:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs540421791:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs9913081",32]
["ENSG00000238083","LRRC37A2",17,44588877,44633016,1,"protein_coding",474170,"LRRC37A2","NA","NA",7,19.03,2739,{"v":8.05734e-120,"d":"8.06E-120"},{"v":1.51829e-103,"d":"1.52E-103"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Mesenchymal_Stem_Cell",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs2732699;rs199460;17:44617964_TA_T;rs112557952;17:44858598_CA_C;rs577976641;rs199500;17:44286218_CA_C;17:44360154_AAG_A;rs9913081;rs201647884;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;rs56755526;17:44286218_CA_C:rs16940904;rs112557952:rs16940904;rs199500:rs16940904;rs112557952:rs16940904:rs16940904;rs199460:rs16940904;rs112557952:rs143234563",32]
["ENSG00000185829","ARL17A",17,44594068,44657088,-1,"protein_coding",51326,"ARL17A","NA",-2.38258287,6,19.03,2737,{"v":3.41734e-19,"d":"3.42E-19"},{"v":6.22486e-21,"d":"6.22E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;17:44617964_TA_T;rs2732699;rs199460;rs112557952;17:44858598_CA_C;rs577976641;rs199500;17:44286218_CA_C;17:44360154_AAG_A;rs9913081;rs201647884;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622;rs56755526",32]
["ENSG00000073969","NSF",17,44668035,44834830,1,"protein_coding",4905,"NSF",0.713682130183303,-0.566246769,62,17.18,2717,{"v":4.17256e-08,"d":"4.17E-08"},{"v":5.07065e-12,"d":"5.07E-12"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;17:44858598_CA_C;rs2732699;rs199460;rs112557952;rs199500;rs56755526;rs199470;rs577976641;rs9913081;17:44286218_CA_C;rs55938136;rs546735951;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs35076622",32]
["ENSG00000108379","WNT3",17,44839872,44910520,-1,"protein_coding",7473,"WNT3",0.946108101336536,-0.191110949,42,16.08,1900,{"v":4.83642e-27,"d":"4.84E-27"},{"v":1.5414e-26,"d":"1.54E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Mesenchymal_Stem_Cell:hESC",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs56755526;rs199460;rs199500;17:44858598_CA_C;rs2732699;rs112557952;rs9913081;17:44286218_CA_C;17:43511281_TGGCTAACACGGTGAAACCCC_T;rs16940904:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904;rs577976641;rs199460:rs16940904;rs2732699:rs16940904;rs112557952:rs199470:rs16940904;rs546608798:rs16940904;17:44360154_AAG_A;rs199500:rs16940904",32]
["ENSG00000158955","WNT9B",17,44910567,44964096,1,"protein_coding",7484,"WNT9B",0.0516168107144711,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Mesenchymal_Stem_Cell:hESC",{"v":2.4e-12,"d":"2.40E-12"},"rs16940904:rs16940904;rs2732699;rs199460;17:44286218_CA_C:rs16940904;17:44286218_CA_C;rs112557952:rs16940904;rs577976641;rs199460:rs16940904;rs9913081;rs2732699:rs16940904;rs112557952:rs199470:rs16940904;rs546608798:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904;rs56755526;rs199500",32]
["ENSG00000108433","GOSR2",17,45000483,45105003,1,"protein_coding",9570,"GOSR2",2.8919421780916003E-4,0.147390712,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.9E-13,"d":"3.90E-13"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs199460;rs199460:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;rs577976641;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs16940904;rs56755526;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs9913081",32]
["ENSG00000262633","RP11-156P1.2",17,45000499,45124520,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.9E-13,"d":"3.90E-13"},"rs16940904;rs2732699;rs9913081;17:44286218_CA_C;rs112557952:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs16940904:rs16940904;rs199460;rs199460:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;rs577976641;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs16940904;rs56755526;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs9913081",32]
["ENSG00000179673","RPRML",17,45055523,45056614,-1,"protein_coding",388394,"RPRML",0.421294822682809,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2E-13,"d":"3.20E-13"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs9913081;17:44286218_CA_C:rs16940904;17:44286218_CA_C;rs112557952:rs16940904:rs16940904;rs112557952:rs16940904;rs199460:rs16940904;rs2732699:rs16940904;rs577976641;17:44360154_AAG_A;rs112557952:rs2732699:rs16940904;rs112557952:rs2696531:rs16940904;rs9913081:rs16940904;rs112557952:rs55938136:rs16940904;17:43511281_TGGCTAACACGGTGAAACCCC_T:rs16940904;rs112557952:rs9913081:rs16940904;rs199460:rs540421791:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs16940904;rs546735951;rs35076622:rs16940904;rs199500:17:44858598_CA_C:rs16940904;rs199500:rs199500",32]
["ENSG00000004897","CDC27",17,45195069,45266788,-1,"protein_coding",996,"CDC27",0.486673202422918,-0.787143256,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.5E-13,"d":"4.50E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;rs112557952:rs16940904;17:44286218_CA_C;rs199460:rs540421791:rs16940904;17:44360154_AAG_A;rs577976641;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs199460:rs16940904;rs112557952:rs143234563:rs16940904;rs56755526;rs199500",32]
["ENSG00000198336","MYL4",17,45277812,45301045,1,"protein_coding",4635,"MYL4",0.000175624794353708,-0.333740158,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.5E-13,"d":"4.50E-13"},"rs16940904;rs2732699;rs577976641;rs199460;17:44286218_CA_C;rs112557952:rs16940904;rs199460:rs16940904;rs9913081;17:44286218_CA_C:rs16940904:rs16940904;rs2732699:rs16940904;17:44360154_AAG_A;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44286218_CA_C:rs16940904;rs112557952:rs540421791:rs16940904;17:44617964_TA_T;rs112557952:rs143234563:rs16940904;rs56755526;rs199500",32]
["ENSG00000259207","ITGB3",17,45331212,45421658,1,"protein_coding",3690,"ITGB3",0.141699544644917,-0.21470934,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.5e-13,"d":"6.50E-13"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs9913081;17:44286218_CA_C:rs16940904;17:44360154_AAG_A;rs577976641;17:44286218_CA_C;rs112557952:rs16940904;17:44617964_TA_T;rs112557952:rs16940904:rs16940904;rs199460:rs16940904;rs112557952:rs143234563",32]
["ENSG00000259753","ITGB3",17,45331263,45421658,1,"protein_coding",3690,"ITGB3","NA",-0.21470934,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.5e-13,"d":"6.50E-13"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs9913081;17:44286218_CA_C:rs16940904;17:44360154_AAG_A;rs577976641;17:44286218_CA_C;rs112557952:rs16940904;17:44617964_TA_T;rs112557952:rs16940904:rs16940904;rs199460:rs16940904;rs112557952:rs143234563",32]
["ENSG00000178852","EFCAB13",17,45400656,45518678,1,"protein_coding",124989,"EFCAB13",{"v":8.2199210022743e-19,"d":"8.22E-19"},-0.190444586,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.5E-10,"d":"1.50E-10"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs199500",32]
["ENSG00000108424","KPNB1",17,45726842,45762871,1,"protein_coding",3837,"KPNB1",0.999994327501246,-0.517927071,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.5E-13,"d":"4.50E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C:rs16940904;17:44286218_CA_C:rs16940904:rs16940904;rs112557952:rs16940904;17:44286218_CA_C;rs199460:rs540421791:rs16940904;rs56755526;rs199500:rs16940904;17:44858598_CA_C;rs112557952;17:44360154_AAG_A;rs577976641;17:44617964_TA_T;rs199460:rs16940904;rs112557952:rs143234563",32]
["ENSG00000073861","TBX21",17,45810610,45823485,1,"protein_coding",30009,"TBX21",0.963242650804377,0.083150474,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.5E-10,"d":"1.50E-10"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs199500",32]
["ENSG00000189120","SP6",17,45922279,45933240,-1,"protein_coding",80320,"SP6",0.0229475656346052,-1.129577219,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.5e-13,"d":"6.50E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C:rs16940904;17:44360154_AAG_A;rs577976641;17:44286218_CA_C;rs112557952:rs16940904;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs16940904:rs16940904;rs199460:rs16940904;rs112557952:rs143234563:rs16940904;rs56755526;rs199500",32]
["ENSG00000108439","PNPO",17,46018872,46025654,1,"protein_coding",55163,"PNPO",{"v":3.71896087830709e-05,"d":"3.72E-05"},0.179349996,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.5E-10,"d":"1.50E-10"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs199500",32]
["ENSG00000167183","PRR15L",17,46029333,46035244,-1,"protein_coding",79170,"PRR15L",0.481246950810061,0.303263346,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.5E-10,"d":"1.50E-10"},"rs16940904;rs56755526;rs199460;rs199500:rs16940904;17:44858598_CA_C;rs2732699;rs112557952;rs199500",32]
["ENSG00000120094","HOXB1",17,46605888,46608359,-1,"protein_coding",3211,"HOXB1",0.115199709546097,-0.795581734,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":6.5e-13,"d":"6.50E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C:rs16940904;17:44360154_AAG_A;rs577976641;17:44286218_CA_C;rs112557952:rs16940904;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs16940904:rs16940904;rs199460:rs16940904;rs112557952:rs143234563",32]
["ENSG00000173917","HOXB2",17,46618256,46623441,-1,"protein_coding",3212,"HOXB2",1.83830846418713E-3,0.974079452,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":6.5e-13,"d":"6.50E-13"},"rs16940904;rs2732699;rs9913081;rs199460;17:44286218_CA_C:rs16940904;17:44360154_AAG_A;rs577976641;17:44286218_CA_C;rs112557952:rs16940904;17:44858598_CA_C;rs112557952;rs199500:rs16940904;17:44617964_TA_T;rs112557952:rs16940904:rs16940904;rs199460:rs16940904;rs112557952:rs143234563",32]
["ENSG00000206181","TCEB3B",18,44558943,44561988,-1,"protein_coding",51224,"TCEB3B",{"v":1.80367559188731E-8,"d":"1.80E-08"},-0.015254462,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.6E-9,"d":"3.60E-09"},"rs2000827:rs7231011:rs3883367:rs752295194",33]
["ENSG00000267228","IER3IP1",18,44661027,44702652,-1,"protein_coding",51124,"IER3IP1","NA",-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.6e-11,"d":"3.60E-11"},"rs9947678;rs10502902;rs3841750:rs7231011:rs3883367:rs2000827:rs3841750",33]
["ENSG00000134049","IER3IP1",18,44681413,44702745,-1,"protein_coding",51124,"IER3IP1",0.0184346889412637,-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.6e-11,"d":"3.60E-11"},"rs9947678;rs10502902;rs3841750:rs7231011:rs3883367:rs2000827:rs3841750",33]
["ENSG00000215474","SKOR2",18,44746293,44775554,-1,"protein_coding",652991,"SKOR2",0.611171343025554,-0.166850887,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.6e-11,"d":"3.60E-11"},"rs9947678;rs10502902;rs3841750:rs7231011:rs3883367:rs2000827:rs3841750:rs752295194",33]
["ENSG00000184828","ZBTB7C",18,45553044,45937123,-1,"protein_coding",201501,"ZBTB7C",0.907221460237709,-0.062747095,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-23,"d":"1.30E-23"},"rs35739561:rs7228085:rs9304381:rs9947684:rs374401823:rs9304381;rs1540037:rs118043171:rs7230869:rs4939888:rs35739561;rs1540036:rs1540037:rs1540036:rs763363223:rs62101765:rs7505352:rs17657001:rs11875988;rs62101773:rs80175721:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs2000827:rs6507945:rs12965067:rs7232836:rs6507945;rs12965067;rs7232836:rs3883367:rs1540041:rs7505997:rs7231011:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs10639158:rs1540041;rs7231011:rs10502902:rs9947678;rs10502902;rs3841750:rs3841750:rs752295194:rs58191032",33]
["ENSG00000141627","DYM",18,46570039,46987717,-1,"protein_coding",54808,"DYM",{"v":5.18111501130597e-09,"d":"5.18E-09"},-0.135200517,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.5e-12,"d":"1.50E-12"},"rs3883367:rs10639158:rs7231011:rs1540041;rs7231011:rs1540041:rs80175721:rs2000827:rs10502902:rs9947678;rs10502902;rs3841750:18:47280133_TACACACACACAC_T:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs7505997:rs3841750",33]
["ENSG00000177576","C18orf32",18,47008028,47013622,-1,"protein_coding",497661,"C18orf32",0.18275268888643,-0.238183839,0,0,1,{"v":4.56943e-05,"d":"4.57E-05"},{"v":7.11808e-09,"d":"7.12E-09"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3E-23,"d":"1.30E-23"},"rs73959582;rs3883367:rs7231011:rs1540041;rs7231011:rs1540041:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223:rs17657001:rs11875988;rs62101773:rs80175721:rs2000827:rs6507945:rs12965067:rs7505997:rs10502902:rs9947678;rs10502902;rs3841750:rs6507945;rs12965067;rs7232836:rs7232836:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs10639158:rs3841750:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs752295194:rs80204526:rs77535126:rs7228085:rs9947684:rs374401823:rs118043171:rs35739561;rs1540036:rs1540037:rs1540036:rs7505352:rs58191032:rs17798991:rs77960347;rs80204526:rs77960347:rs4121823",33]
["ENSG00000215472","RPL17-C18orf32",18,47008051,47017956,-1,"protein_coding",100526842,"RPL17-C18orf32",0.605942171595584,-0.340213428,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3E-23,"d":"1.30E-23"},"rs3883367:rs7231011:rs1540041;rs7231011:rs1540041:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223:rs17657001:rs11875988;rs62101773:rs80175721:rs2000827:rs6507945:rs12965067:rs7505997:rs10502902:rs9947678;rs10502902;rs3841750:rs6507945;rs12965067;rs7232836:rs7232836:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs10639158:rs3841750:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs752295194:rs80204526:rs77535126:rs7228085:rs9947684:rs374401823:rs118043171:rs35739561;rs1540036:rs1540037:rs1540036:rs7505352:rs58191032:rs17798991:rs77960347;rs80204526:rs77960347:rs4121823",33]
["ENSG00000265681","RPL17",18,47014851,47018906,-1,"protein_coding",6139,"RPL17",0.494059426420399,0.186983574,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3E-23,"d":"1.30E-23"},"rs3883367:rs7231011:rs1540041;rs7231011:rs1540041:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223:rs17657001:rs11875988;rs62101773:rs80175721:rs2000827:rs6507945:rs12965067:rs7505997:rs10502902:rs9947678;rs10502902;rs3841750:rs6507945;rs12965067;rs7232836:rs7232836:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs10639158:rs3841750:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs752295194:rs80204526:rs77535126:rs7228085:rs9947684:rs374401823:rs118043171:rs35739561;rs1540036:rs1540037:rs1540036:rs7505352:rs58191032:rs17798991:rs77960347;rs80204526:rs77960347:rs4121823",33]
["ENSG00000101670","LIPG",18,47087069,47119272,1,"protein_coding",9388,"LIPG",{"v":8.35570265503166e-05,"d":"8.36E-05"},-0.057562727,29,24.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3E-23,"d":"1.30E-23"},"rs17798991;rs77960347;rs80204526;rs77535126;rs4121823;rs1105654;rs10853582;rs3883367:rs1540041:rs7231011:rs2000827:rs62101765:rs763363223:rs17657001:rs11875988;rs62101773:rs80175721:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs6507945:rs12965067:rs7505997:rs1540041;rs7231011:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs7232836:rs10639158:rs6507945;rs12965067;rs7232836:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs10502902:rs9947678;rs10502902;rs3841750:rs3841750",33]
["ENSG00000167315","ACAA2",18,47309869,47340330,-1,"protein_coding",10449,"ACAA2","NA","NA",17,6.852,74,{"v":5.37008e-08,"d":"5.37E-08"},{"v":6.07479e-14,"d":"6.07E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3E-23,"d":"1.30E-23"},"rs7231011;rs2000827;rs3883367;rs10639158;rs1540041;rs10502902;rs17798991:rs3883367:rs1540041:rs7231011:rs62101765:rs763363223:rs17657001:rs11875988;rs62101773:rs80175721:rs2000827:rs10502902:rs9947678;rs3841750:rs80204526:rs77535126:rs77960347;rs80204526:rs77960347:rs4121823:rs35739561:rs7228085:rs9304381:rs9947684:rs374401823:rs9304381;rs1540037:rs118043171:rs7230869:rs4939888:rs35739561;rs1540036:rs1540037:rs1540036:rs7505352:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs6507945:rs12965067:rs7232836:18:47280133_TACACACACACAC_T:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs7505997",33]
["ENSG00000266997","RP11-886H22.1",18,47322163,47363993,-1,"protein_coding","NA","NA","NA","NA",27,13.18,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-23,"d":"1.20E-23"},"rs7231011;rs3883367;rs10639158;rs1540041;rs80175721;rs80204526:rs77535126:rs3883367:rs10639158:rs7231011:rs1540041;rs7231011:rs1540041:18:47280133_TACACACACACAC_T:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs7505997:rs80175721:rs2000827:rs9947678;rs10502902;rs3841750:rs3841750:rs17798991:rs77960347;rs80204526:rs77960347:rs4121823:rs1105654;rs10853582:rs10853582:rs7241596:rs1105654:rs7229377:rs34802337:rs11663245:rs73959582:rs35311766:rs7235080:rs11662059:rs7230869:rs9304381:rs7229658:rs35739561:rs7228085:rs9947684:rs374401823:rs9304381;rs1540037:rs118043171:rs4939888:rs35739561;rs1540036:rs1540037:rs1540036:rs763363223:rs62101765:rs7505352:rs17657001:rs11875988;rs62101773:rs11875988:rs763363223;rs11875988:rs62101773:18:47211493_ACATC_A:rs6507945:rs12965067:rs7232836:rs6507945;rs12965067;rs7232836",33]
["ENSG00000167306","MYO5B",18,47349183,47721463,-1,"protein_coding",4645,"MYO5B",{"v":5.4231747689238e-10,"d":"5.42E-10"},0.470845589,199,24.3,11,{"v":1.87225e-08,"d":"1.87E-08"},{"v":2.72847E-12,"d":"2.73E-12"},"GTEx/v8/Artery_Aorta","-","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.3e-20,"d":"8.30E-20"},"rs1540041;rs7231011;rs3883367;rs80175721;rs2000827;rs10502902;rs9947678;rs3841750;rs752295194;rs58191032;rs80204526:rs77535126:rs9947678;rs3841750:rs7231011:rs3883367:rs2000827:rs3841750:rs17798991:rs77960347;rs80204526:rs77960347:rs4121823:rs752295194:rs58191032:rs80175721:rs10639158:rs1540041;rs7231011:rs1540041:rs10502902:18:47280133_TACACACACACAC_T:rs9947678;rs9964067;18:47280133_TACACACACACAC_T:rs9964067:rs9947678:rs9947678;rs9964067:rs7505997",33]
["ENSG00000172361","CCDC11",18,47753563,47792892,-1,"protein_coding",220136,"CCDC11",{"v":1.5987996365213e-13,"d":"1.60E-13"},-0.596742517,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-23,"d":"1.30E-23"},"rs1540041;rs7231011:rs1540041:rs3883367:rs7231011:rs35739561:rs9304381;rs1540037:rs9304381:rs7230869:rs4939888:rs62101765:rs763363223:rs17657001:rs11875988;rs62101773:rs80175721:rs2000827:rs80204526:rs77535126:rs10502902:rs9947678;rs10502902;rs3841750:rs3841750:rs752295194:rs58191032",33]
["ENSG00000154832","CXXC1",18,47808713,47814674,-1,"protein_coding",30827,"CXXC1",0.99786210530366,-0.476982834,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.7e-08,"d":"7.70E-08"},"rs7231011:rs3883367",33]
["ENSG00000154839","SKA1",18,47901365,47920543,1,"protein_coding",220134,"SKA1",{"v":1.32265949651803E-6,"d":"1.32E-06"},0.423231094,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3e-17,"d":"3.00E-17"},"rs80204526:rs77535126:rs80175721:rs2000827:rs7231011:rs3883367:rs752295194:rs9947678;rs10502902;rs3841750:rs3841750",33]
["ENSG00000129353","SLC44A2",19,10713133,10755235,1,"protein_coding",57153,"SLC44A2",0.0414645881648824,-0.378860929,0,0,2,{"v":2.77111E-5,"d":"2.77E-05"},0.000289454,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":1.8E-5,"d":"1.80E-05"},"rs142158911",34]
["ENSG00000142453","CARM1",19,10982189,11033453,1,"protein_coding",10498,"CARM1",0.999357708272541,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7.8e-13,"d":"7.80E-13"},"rs142158911",34]
["ENSG00000130733","YIPF2",19,11033444,11039357,-1,"protein_coding",78992,"YIPF2",1.09917458451604E-3,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":7.8e-13,"d":"7.80E-13"},"rs142158911",34]
["ENSG00000142444","C19orf52",19,11039409,11044211,1,"protein_coding",90580,"C19orf52",0.00198991933916563,-0.096033732,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":7.8e-13,"d":"7.80E-13"},"rs142158911",34]
["ENSG00000130164","LDLR",19,11200038,11244492,1,"protein_coding",3949,"LDLR",{"v":2.59266073718312e-16,"d":"2.59E-16"},0.415051182,45,13.85,0,"NA","NA","NA","NA","No","NA",{"v":7.8e-13,"d":"7.80E-13"},"rs142158911",34]
["ENSG00000130158","DOCK6",19,11309971,11373157,-1,"protein_coding",57572,"DOCK6",{"v":2.83089712599404e-19,"d":"2.83E-19"},"NA",11,23.1,1,1.59023E-4,0.0160196,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":4.6e-11,"d":"4.60E-11"},"rs737338",34]
["ENSG00000130173","C19orf80",19,11348178,11352619,1,"protein_coding",55908,"C19orf80",{"v":2.61107498638975e-06,"d":"2.61E-06"},-0.019228124,5,23.1,0,"NA","NA","NA","NA","No","NA",{"v":4.6e-11,"d":"4.60E-11"},"rs737338",34]
["ENSG00000105518","TMEM205",19,11453452,11457194,-1,"protein_coding",374882,"TMEM205",0.394574027164483,-0.471673866,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":2.6e-12,"d":"2.60E-12"},"rs142158911",34]
["ENSG00000173928","SWSAP1",19,11485361,11487627,1,"protein_coding",126074,"SWSAP1",0.000134670403718243,-0.594213988,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":7.8e-13,"d":"7.80E-13"},"rs142158911",34]
["ENSG00000102575","ACP5",19,11685475,11689823,-1,"protein_coding",54,"ACP5",0.123568347500175,-0.16646465,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.8e-13,"d":"7.80E-13"},"rs142158911",34]
["ENSG00000196757","ZNF700",19,12035883,12061588,1,"protein_coding",90592,"ZNF700",{"v":4.39166088843519E-11,"d":"4.39E-11"},0.364854347,0,0,3,{"v":4.47579e-05,"d":"4.48E-05"},3.03929E-3,"GTEx/v8/Artery_Tibial","-","No","NA",{"v":1.9e-07,"d":"1.90E-07"},"rs737338",34]
["ENSG00000141979","CTD-3222D19.2",19,16589878,16739015,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.5e-27,"d":"1.50E-27"},"rs116962777:rs143729015:rs533090193",35]
["ENSG00000105085","MED26",19,16685718,16739873,-1,"protein_coding",9441,"MED26",0.948549941884627,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.5e-27,"d":"1.50E-27"},"rs116962777:rs143729015:rs533090193",35]
["ENSG00000105642","KCNN1",19,18062102,18110889,1,"protein_coding",3780,"KCNN1",0.931699633359926,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626",35]
["ENSG00000254858","MPV17L2",19,18303992,18307758,1,"protein_coding",84769,"MPV17L2",{"v":1.67296107198305e-07,"d":"1.67E-07"},0.464900432,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.5e-26,"d":"1.50E-26"},"rs143729015",35]
["ENSG00000105650","PDE4C",19,18318771,18366229,-1,"protein_coding",5143,"PDE4C",{"v":4.88574724786651e-05,"d":"4.89E-05"},0.288881628,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.9e-19,"d":"6.90E-19"},"rs143729015",35]
["ENSG00000130511","SSBP4",19,18529674,18545372,1,"protein_coding",170463,"SSBP4",0.96165888216155,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-21,"d":"3.20E-21"},"rs143729015",35]
["ENSG00000105656","ELL",19,18553473,18632937,-1,"protein_coding",8178,"ELL",0.940941238331597,-0.635599911,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Mesenchymal_Stem_Cell",{"v":1.5e-27,"d":"1.50E-27"},"rs143729015:rs73004826:rs116962777:rs533090193",35]
["ENSG00000105701","FKBP8",19,18642561,18654887,-1,"protein_coding",23770,"FKBP8",0.9787380986207,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.5e-26,"d":"1.50E-26"},"rs143729015",35]
["ENSG00000221983","UBA52",19,18682540,18688360,1,"protein_coding",7311,"UBA52",0.4468000697986,1.709183735,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.5e-27,"d":"1.50E-27"},"rs143729015:rs73004826:rs116962777:rs533090193:rs73001020;rs143729015",35]
["ENSG00000006016","CRLF1",19,18683030,18718551,-1,"protein_coding",9244,"CRLF1",0.026855594173361,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.5e-27,"d":"1.50E-27"},"rs73004826:rs116962777:rs143729015:rs533090193:rs73001020;rs143729015",35]
["ENSG00000006015","C19orf60",19,18699495,18703146,1,"protein_coding",55049,"C19orf60",0.249879077699029,0.549025716,0,0,1,{"v":9.44404e-05,"d":"9.44E-05"},{"v":3.85859E-8,"d":"3.86E-08"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.5e-27,"d":"1.50E-27"},"19:19684139_TAC_T;rs143729015:rs73004826:rs116962777:rs533090193:rs73001020;rs143729015",35]
["ENSG00000105696","TMEM59L",19,18718240,18731849,1,"protein_coding",25789,"TMEM59L",0.0151007864967939,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.5e-27,"d":"1.50E-27"},"rs73004826:rs116962777:rs143729015:rs533090193:rs73001020;rs143729015",35]
["ENSG00000105662","CRTC1",19,18794487,18893004,1,"protein_coding",23373,"CRTC1",0.980548236291021,-2.587605964,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.5e-26,"d":"1.50E-26"},"rs143729015",35]
["ENSG00000223802","CERS1",19,18979361,19007536,-1,"protein_coding",10715,"CERS1",0.0454570437212016,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-88,"d":"1.00E-88"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs182611493:rs2285626;rs17216693;19:19510831_AT_A",35]
["ENSG00000130283","GDF1",19,18979361,19006905,-1,"protein_coding",2657,"GDF1",0.544923744446604,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-88,"d":"1.00E-88"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs182611493:rs2285626;rs17216693;19:19510831_AT_A",35]
["ENSG00000105669","COPE",19,19010323,19030206,-1,"protein_coding",11316,"COPE",0.6166479413462,-0.427025289,0,0,1,{"v":6.07344e-05,"d":"6.07E-05"},{"v":9.06241e-06,"d":"9.06E-06"},"GTEx/v8/Heart_Left_Ventricle","-","No","NA",{"v":6.8e-09,"d":"6.80E-09"},"rs73004826",35]
["ENSG00000268193","AC002985.3",19,19017822,19045206,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs144787624",35]
["ENSG00000064607","SUGP2",19,19101697,19144832,-1,"protein_coding",10147,"SUGP2",0.999366871236062,0.523631183,7,12.96,31,{"v":6.38872E-7,"d":"6.39E-07"},{"v":4.0018e-05,"d":"4.00E-05"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.6e-107,"d":"1.60E-107"},"rs143729015;rs73001020;rs116962777;rs533090193;rs60811331;rs61061000;rs143729015:rs61061000:rs60811331:rs8100140:rs11882123:rs58542926:rs2285626:rs144787624:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs142915079:rs61061000;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:19:19269404_GA_G:rs117877390",35]
["ENSG00000105676","ARMC6",19,19144384,19170563,1,"protein_coding",93436,"ARMC6",{"v":7.24407726209859e-07,"d":"7.24E-07"},"NA",3,4.992,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.6e-107,"d":"1.60E-107"},"rs533090193;rs143729015;rs142915079;rs143729015:rs61061000:rs60811331:rs8100140:rs11882123:rs58542926:rs2285626:rs144787624:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs142915079:rs61061000;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:19:19269404_GA_G:rs117877390",35]
["ENSG00000181035","SLC25A42",19,19174808,19223697,1,"protein_coding",284439,"SLC25A42",0.208308450498004,-0.880389707,2,0.249,1,{"v":6.84166e-05,"d":"6.84E-05"},0.0196554,"GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.5e-27,"d":"1.50E-27"},"rs142915079;rs143729015;19:19684139_TAC_T;rs116962777:rs143729015:rs533090193:rs61061000;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:rs61061000:19:19269404_GA_G:rs60811331",35]
["ENSG00000064545","TMEM161A",19,19229978,19249322,-1,"protein_coding",54929,"TMEM161A",{"v":2.04658505555468e-06,"d":"2.05E-06"},-0.270254201,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":7.6e-92,"d":"7.60E-92"},"rs142915079:rs116962777:rs143729015:rs533090193:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs2285626:rs182611493:rs58542926:rs144787624:rs117877390",35]
["ENSG00000064489","MEF2BNB-MEF2B",19,19256376,19302967,-1,"protein_coding",4207,"MEF2BNB-MEF2B",0.247287511423171,-0.149548186,101,12.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs61061000;rs28672836;19:19260892_CAAAAAAAAA_C;19:19269404_GA_G;rs60811331;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",35]
["ENSG00000213999","MEF2B",19,19256377,19303400,-1,"protein_coding",100271849,"MEF2B",0.590447262915793,"NA",101,12.47,38,{"v":3.23375e-08,"d":"3.23E-08"},0.000173774,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs61061000;rs28672836;19:19260892_CAAAAAAAAA_C;19:19269404_GA_G;rs60811331;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",35]
["ENSG00000254901","MEF2BNB",19,19287712,19303400,-1,"protein_coding",729991,"MEF2BNB","NA",0.579437175,60,12.34,51,{"v":7.7977e-15,"d":"7.80E-15"},{"v":3.62201e-19,"d":"3.62E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs61061000;rs60811331;rs8100140;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",35]
["ENSG00000064490","RFXANK",19,19303008,19312678,1,"protein_coding",8625,"RFXANK",0.000671163624692492,0.789997306,21,9.408,3,0.000100607,0.0177117,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs60811331;rs61061000;rs8100140;rs182611493;rs73001020;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",35]
["ENSG00000184162","NR2C2AP",19,19312225,19314233,-1,"protein_coding",126382,"NR2C2AP",0.527167735331819,-0.417894074,2,6.326,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":5.2e-91,"d":"5.20E-91"},"rs8100140;rs182611493;rs61061000:rs60811331:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs58542926:rs2285626",35]
["ENSG00000130287","NCAN",19,19322782,19363042,1,"protein_coding",1463,"NCAN",0.154546738217425,-1.280770396,11,23,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":1.6e-107,"d":"1.60E-107"},"rs8100140;rs182611493;19:19324314_TG_T;rs3761077;rs58542926;rs34298424;rs11882123;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs182611493:19:19510831_AT_A:rs144787624",35]
["ENSG00000187664","HAPLN4",19,19366450,19373605,-1,"protein_coding",404037,"HAPLN4",0.0326847848265823,0.204997517,20,26.2,219,{"v":6.79586E-20,"d":"6.80E-20"},{"v":6.88492e-19,"d":"6.88E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":1.2e-108,"d":"1.20E-108"},"rs11882123;rs58542926;rs2285626;19:19510831_AT_A;rs117877390;rs182611493;19:19684139_TAC_T;rs17216693;rs10407283;rs111503239;rs7245672;rs143333049;rs8100204;rs34298424:rs58542926",35]
["ENSG00000213996","TM6SF2",19,19375173,19384200,-1,"protein_coding",53345,"TM6SF2",{"v":1.93541173325793e-05,"d":"1.94E-05"},"NA",36,26.2,282,{"v":1.17275e-20,"d":"1.17E-20"},{"v":8.90299e-16,"d":"8.90E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.2e-108,"d":"1.20E-108"},"rs58542926;rs11882123;rs2285626;19:19510831_AT_A;rs117877390;rs182611493;rs35431065;rs8100204;rs17216693;19:19684139_TAC_T;rs7245672;19:19756073_AGCC_A;rs10407283;rs111503239;rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs144787624",35]
["ENSG00000105705","SUGP1",19,19386827,19431653,-1,"protein_coding",57794,"SUGP1",0.9996355600486,"NA",86,26.2,14,{"v":4.84498e-06,"d":"4.84E-06"},{"v":5.87709e-05,"d":"5.88E-05"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":1.2e-108,"d":"1.20E-108"},"rs11882123;rs117877390;rs58542926;rs182611493;rs2285626;19:19510831_AT_A;rs35431065;rs8100204;rs73001020;rs17216693;rs747862826;19:19438110_GTATT_G;rs7245672;rs11882123:rs2285626:rs2285626",35]
["ENSG00000129933","MAU2",19,19431490,19469563,1,"protein_coding",23383,"MAU2",0.999717755369344,0.014423646,88,15.92,20,{"v":2.45442e-05,"d":"2.45E-05"},0.0377692,"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":7.6e-92,"d":"7.60E-92"},"rs2285626;19:19510831_AT_A;rs11882123;rs58542926;rs747862826;19:19438110_GTATT_G;rs73001020;rs182611493;rs144787624;rs117877390;rs11882123:rs2285626:rs2285626",35]
["ENSG00000167491","GATAD2A",19,19496635,19619740,1,"protein_coding",54815,"GATAD2A",0.995362828250654,-0.496926306,124,19.09,29,{"v":9.95736e-06,"d":"9.96E-06"},0.0106309,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":7.6e-92,"d":"7.60E-92"},"rs11882123;rs2285626;19:19510831_AT_A;rs58542926;19:19756073_AGCC_A;rs17216693;19:19503203_GT_G;rs73001020;19:19684139_TAC_T;rs77653002;rs144787624;rs117877390;rs143729015:rs11882123:rs58542926:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs2285626:rs144787624",35]
["ENSG00000178093","TSSK6",19,19623227,19626838,-1,"protein_coding",83983,"TSSK6",0.587550746537451,-1.568432771,21,19.09,25,{"v":8.90205e-06,"d":"8.90E-06"},{"v":3.58402e-05,"d":"3.58E-05"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex",{"v":3.8e-65,"d":"3.80E-65"},"rs11882123;rs2285626;rs144787624;rs117877390;rs17216693;19:19510831_AT_A;rs7245672;rs11882123:rs2285626",35]
["ENSG00000186010","NDUFA13",19,19626545,19644285,1,"protein_coding",51079,"NDUFA13",1.21026586319051E-4,-0.285091511,24,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.8e-65,"d":"3.80E-65"},"rs11882123;rs144787624;rs2285626;rs117877390;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",35]
["ENSG00000250067","YJEFN3",19,19627036,19648390,1,"protein_coding",374887,"YJEFN3",{"v":2.63542608769062e-06,"d":"2.64E-06"},"NA",24,19.09,252,{"v":1.26288E-18,"d":"1.26E-18"},{"v":3.19891e-16,"d":"3.20E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex",{"v":1.6e-107,"d":"1.60E-107"},"rs11882123;rs144787624;rs2285626;rs117877390;rs17216693;19:19510831_AT_A;rs58542926;rs73001020;rs10407283;rs111503239;19:19756073_AGCC_A;rs7245672;rs12608822;rs75916629;rs143729015;rs892023;19:19684139_TAC_T;rs11882123:rs2285626",35]
["ENSG00000258674","CTC-260F20.3",19,19627036,19646885,1,"protein_coding","NA","NA","NA","NA",22,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.8e-65,"d":"3.80E-65"},"rs11882123;rs144787624;rs2285626;rs117877390;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",35]
["ENSG00000160161","CILP2",19,19649057,19657468,1,"protein_coding",148113,"CILP2",0.000278936233123941,-0.132917182,17,11.63,180,{"v":2.5641e-19,"d":"2.56E-19"},{"v":7.52088e-21,"d":"7.52E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":5.2e-91,"d":"5.20E-91"},"rs11882123;rs2285626;rs17216693;19:19510831_AT_A;rs58542926;rs892023;19:19684139_TAC_T;rs7245672;rs10407283;rs111503239;rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs144787624:rs117877390:rs2285626;19:19510831_AT_A:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239",35]
["ENSG00000105717","PBX4",19,19672522,19729725,-1,"protein_coding",80714,"PBX4",0.006772126187306,-0.679896521,94,18.31,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3.1e-85,"d":"3.10E-85"},"rs892023;rs58542926;rs17216693;19:19684139_TAC_T;rs10407283;rs111503239;19:19756073_AGCC_A;rs7245672;19:19684139_TAC_T:rs7245672:rs58542926",35]
["ENSG00000064547","LPAR2",19,19734477,19739739,-1,"protein_coding",9170,"LPAR2",0.337269896843433,-0.426142953,26,18.31,193,{"v":4.1384e-34,"d":"4.14E-34"},{"v":1.22846e-27,"d":"1.23E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":1.9e-84,"d":"1.90E-84"},"rs7245672;19:19684139_TAC_T;rs58542926;19:19756073_AGCC_A;rs10407283;rs111503239;19:19749587_CT_C;rs11882123",35]
["ENSG00000089639","GMIP",19,19740285,19754476,-1,"protein_coding",51291,"GMIP",{"v":7.29298933296636e-05,"d":"7.29E-05"},-0.277164354,24,18.31,37,{"v":3.96674e-08,"d":"3.97E-08"},1.36079E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","+","Yes","EP_correlation_cell_type_oneway",{"v":1.7E-76,"d":"1.70E-76"},"19:19684139_TAC_T;rs7245672;rs10407283;rs111503239;rs58542926;19:19756073_AGCC_A;19:19749587_CT_C;rs11882123",35]
["ENSG00000105726","ATP13A1",19,19756007,19774502,-1,"protein_coding",57130,"ATP13A1",0.994473888962369,"NA",8,8.965,116,{"v":3.16696e-16,"d":"3.17E-16"},{"v":9.80314e-12,"d":"9.80E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.2e-108,"d":"1.20E-108"},"rs58542926;19:19756073_AGCC_A;19:19684139_TAC_T;19:19749587_CT_C;rs10407283;rs111503239;rs143729015;rs61061000;rs3761077;rs35431065;rs8100204;rs73001020;rs17216693;rs2285626;19:19510831_AT_A;rs143333049;rs75916629;rs11882123;rs7245672;19:19684139_TAC_T:rs7245672:rs10407283;rs111503239:rs10407283:rs58542926;19:19756073_AGCC_A:19:19749587_CT_C:19:19756073_AGCC_A:rs11882123:rs58542926:rs2285626:rs144787624:rs12608822:rs117414940:rs75916629",35]
["ENSG00000181896","ZNF101",19,19779605,19794318,1,"protein_coding",94039,"ZNF101",{"v":5.76614320550034e-07,"d":"5.77E-07"},-0.001974248,5,11.91,45,{"v":2.56484E-5,"d":"2.56E-05"},{"v":2.22273E-14,"d":"2.22E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":5.8e-90,"d":"5.80E-90"},"19:19756073_AGCC_A;rs143333049;rs61061000;rs58542926;rs3761077;rs7245672;rs11882123:19:19684139_TAC_T:rs7245672:rs10407283;rs111503239:rs10407283:rs58542926;19:19756073_AGCC_A:19:19749587_CT_C:19:19756073_AGCC_A:rs58542926:rs2285626:rs144787624:rs12608822:rs117414940:rs75916629",35]
["ENSG00000105708","ZNF14",19,19821280,19843906,-1,"protein_coding",7561,"ZNF14",{"v":5.71582699182454e-16,"d":"5.72E-16"},-0.140934352,3,9.168,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6E-91,"d":"3.60E-91"},"rs12608822;rs117414940;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:19:19756073_AGCC_A:rs75916629:rs143333049:rs12608822",35]
["ENSG00000081665","ZNF506",19,19896648,19932560,-1,"protein_coding",440515,"ZNF506",{"v":1.99612668014446E-8,"d":"2.00E-08"},-0.298399589,0,0,22,{"v":3.10704e-06,"d":"3.11E-06"},{"v":1.69948E-26,"d":"1.70E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.8e-90,"d":"4.80E-90"},"rs58542926;rs17216693;19:19756073_AGCC_A;rs75916629;rs73001020;rs2285626;rs892023;rs12608822:rs117414940:rs75916629:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs143333049:19:19756073_AGCC_A",35]
["ENSG00000256771","ZNF253",19,19976695,20005483,1,"protein_coding",56242,"ZNF253",{"v":1.33295852799606e-06,"d":"1.33E-06"},0.279040894,0,0,6,{"v":2.0393e-06,"d":"2.04E-06"},{"v":3.16519e-06,"d":"3.17E-06"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9E-19,"d":"2.90E-19"},"rs75916629;rs12608822:rs117414940:rs75916629:rs143333049",35]
["ENSG00000184635","ZNF93",19,20011722,20046384,1,"protein_coding",81931,"ZNF93",0.00169182185612759,0.174728697,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs12608822:rs117414940:rs75916629:rs143333049:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:19:19756073_AGCC_A",35]
["ENSG00000268461","AC007204.1",19,20047769,20048639,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs11882123:rs2285626:rs2285626;rs17216693;19:19510831_AT_A:rs58542926;rs17216693:rs892023:rs17216693:19:19684139_TAC_T:rs892023;19:19684139_TAC_T:rs10407283;rs111503239:rs58542926;19:19756073_AGCC_A:rs7245672:rs10407283:rs111503239:19:19756073_AGCC_A:rs12608822:rs117414940:rs75916629:rs143333049",35]
["ENSG00000197124","ZNF682",19,20107867,20150315,-1,"protein_coding",91120,"ZNF682",{"v":3.67329437341058e-09,"d":"3.67E-09"},1.212036464,0,0,4,{"v":2.00795E-5,"d":"2.01E-05"},0.00051934,"GTEx/v8/Artery_Tibial","-","Yes","Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-107,"d":"1.60E-107"},"rs58542926;rs12608822;rs75916629",35]
["ENSG00000213988","ZNF90",19,20188803,20237885,1,"protein_coding",7643,"ZNF90",{"v":1.22410273221888e-07,"d":"1.22E-07"},1.219480619,2,3.654,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629;rs12608822:rs117414940:rs75916629:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs143333049",35]
["ENSG00000256229","ZNF486",19,20278037,20311299,1,"protein_coding",90649,"ZNF486",{"v":1.88053183954875e-08,"d":"1.88E-08"},1.705728223,3,12.03,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629;rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs75916629:rs12608822:rs117414940",35]
["ENSG00000237440","ZNF737",19,20718631,20748615,-1,"protein_coding",100129842,"ZNF737",{"v":1.10579189398794E-7,"d":"1.11E-07"},1.355633218,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.9E-19,"d":"2.90E-19"},"rs12608822:rs117414940:rs75916629:rs143333049",35]
["ENSG00000188171","ZNF626",19,20802867,20844402,-1,"protein_coding",199777,"ZNF626",{"v":2.3449662444854E-7,"d":"2.34E-07"},10.77102824,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs12608822:rs117414940:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239",35]
["ENSG00000160229","ZNF66",19,20959110,20991922,1,"protein_coding",7617,"ZNF66",{"v":5.45295491875167e-17,"d":"5.45E-17"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2E-14,"d":"2.00E-14"},"rs75916629:rs12608822:rs117414940",35]
["ENSG00000105750","ZNF85",19,21106028,21133503,1,"protein_coding",7639,"ZNF85",{"v":2.27830551125369e-10,"d":"2.28E-10"},1.219956647,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.9E-6,"d":"6.90E-06"},"rs75916629",35]
["ENSG00000118620","ZNF430",19,21203426,21242856,1,"protein_coding",80264,"ZNF430",0.000180790697407956,0.502386975,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs143333049:rs12608822:rs117414940",35]
["ENSG00000160352","ZNF714",19,21264965,21308073,1,"protein_coding",148206,"ZNF714",{"v":7.33708061274363e-06,"d":"7.34E-06"},0.728801136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs75916629:rs12608822:rs117414940",35]
["ENSG00000196705","ZNF431",19,21324827,21373034,1,"protein_coding",170959,"ZNF431",0.000233579258381277,-1.179635714,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6E-7,"d":"1.60E-07"},"rs75916629",35]
["ENSG00000182141","ZNF708",19,21473962,21512227,-1,"protein_coding",7562,"ZNF708",{"v":4.17756094613551e-09,"d":"4.18E-09"},1.095220078,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs143333049:rs12608822:19:19756073_AGCC_A",35]
["ENSG00000172687","ZNF738",19,21541732,21562104,1,"protein_coding",148203,"ZNF738",0.106373218916856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:rs143333049:rs12608822:rs117414940",35]
["ENSG00000196268","ZNF493",19,21579921,21610375,1,"protein_coding",284443,"ZNF493",{"v":3.18649368326509e-08,"d":"3.19E-08"},2.729194243,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs12608822:rs117414940:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:19:19756073_AGCC_A:rs143333049",35]
["ENSG00000269237","CTD-2561J22.3",19,21587961,21674068,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs12608822:rs117414940:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239:19:19756073_AGCC_A:rs143333049",35]
["ENSG00000197013","ZNF429",19,21679484,21739072,1,"protein_coding",353088,"ZNF429",{"v":9.7121420957407e-14,"d":"9.71E-14"},-0.124310103,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-85,"d":"3.10E-85"},"rs75916629:rs12608822:rs117414940:rs10407283;rs111503239:rs10407283:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs111503239",35]
["ENSG00000197020","ZNF100",19,21905568,21950430,-1,"protein_coding",163227,"ZNF100",{"v":7.10189425692909e-13,"d":"7.10E-13"},1.454526972,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9E-19,"d":"2.90E-19"},"rs75916629:rs12608822:rs117414940:rs143333049",35]
["ENSG00000198521","ZNF43",19,21987752,22034927,-1,"protein_coding",7594,"ZNF43",{"v":2.14784246985067e-08,"d":"2.15E-08"},0.35246967,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.9e-09,"d":"3.90E-09"},"rs75916629",35]
["ENSG00000160321","ZNF208",19,22115760,22193751,-1,"protein_coding",7757,"ZNF208",{"v":5.00161251193924e-20,"d":"5.00E-20"},-0.087489856,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell",{"v":2E-14,"d":"2.00E-14"},"rs75916629:rs12608822:rs117414940",35]
["ENSG00000197134","ZNF257",19,22235254,22274282,1,"protein_coding",113835,"ZNF257",{"v":1.12139154354786E-9,"d":"1.12E-09"},1.43553043,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.9E-6,"d":"6.90E-06"},"rs75916629",35]
["ENSG00000196109","ZNF676",19,22361893,22379753,-1,"protein_coding",163223,"ZNF676",{"v":1.6869849435551e-06,"d":"1.69E-06"},0.244027382,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2E-14,"d":"2.00E-14"},"rs75916629:rs12608822:rs117414940",35]
["ENSG00000197360","ZNF98",19,22573821,22715287,-1,"protein_coding",148198,"ZNF98",{"v":1.80227058167028E-6,"d":"1.80E-06"},0.029177521,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.9E-19,"d":"2.90E-19"},"rs75916629:rs143333049:rs12608822",35]
["ENSG00000229676","ZNF492",19,22817126,22850472,1,"protein_coding",57615,"ZNF492",0.0174306218221897,5.430272464,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-09,"d":"3.90E-09"},"rs75916629",35]
["ENSG00000269067","ZNF728",19,23158270,23185978,-1,"protein_coding",388523,"ZNF728",{"v":1.3589524035837e-07,"d":"1.36E-07"},0.005643135,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.6E-7,"d":"1.60E-07"},"rs75916629",35]
["ENSG00000183850","ZNF730",19,23258012,23330021,1,"protein_coding",100129543,"ZNF730",{"v":1.85625397322033E-10,"d":"1.86E-10"},0.541151057,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.1e-07,"d":"4.10E-07"},"rs75916629",35]
["ENSG00000167378","IRGQ",19,44088521,44100287,-1,"protein_coding",126298,"IRGQ",1.19722791198288E-3,-1.836457701,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":5.7e-12,"d":"5.70E-12"},"rs9304644:rs190921611;rs2376867",36]
["ENSG00000124444","ZNF576",19,44100544,44105309,1,"protein_coding",79177,"ZNF576",0.007545747912442,-1.085568404,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":5.7e-12,"d":"5.70E-12"},"rs9304644:rs190921611;rs2376867",36]
["ENSG00000226763","SRRM5",19,44100769,44118649,1,"protein_coding",100170229,"SRRM5",{"v":7.19141934794887e-06,"d":"7.19E-06"},-0.661940966,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":5.7e-12,"d":"5.70E-12"},"rs9304644:rs190921611;rs2376867",36]
["ENSG00000131116","ZNF428",19,44111371,44124026,-1,"protein_coding",126299,"ZNF428",0.720275479182866,-0.650154352,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000105767","CADM4",19,44126520,44143991,-1,"protein_coding",199731,"CADM4",0.979491544538579,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000256294","ZNF225",19,44616334,44637027,1,"protein_coding",7768,"ZNF225",{"v":3.36669333303033e-08,"d":"3.37E-08"},0.547354183,0,0,1,1.18239E-4,0.00794975,"GTEx/v8/Adipose_Subcutaneous","-","Yes","IMR90",{"v":1.1e-27,"d":"1.10E-27"},"rs145887105;rs429358:rs157580:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100",36]
["ENSG00000159917","ZNF235",19,44732882,44809199,-1,"protein_coding",9310,"ZNF235",{"v":1.85820362433789E-10,"d":"1.86E-10"},-0.818454032,0,0,14,{"v":8.96599e-05,"d":"8.97E-05"},0.000592533,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":5.7e-12,"d":"5.70E-12"},"rs9304644",36]
["ENSG00000216588","IGSF23",19,45116940,45140081,1,"protein_coding",147710,"IGSF23","NA",0.573724812,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000073008","PVR",19,45147098,45166850,1,"protein_coding",5817,"PVR",{"v":5.51101308161619e-07,"d":"5.51E-07"},-0.732916848,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-27,"d":"1.10E-27"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791:rs157580:rs429358:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100",36]
["ENSG00000186567","CEACAM19",19,45165545,45187631,1,"protein_coding",56971,"CEACAM19",{"v":5.7765093789489e-07,"d":"5.78E-07"},0.414157593,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000213892","CEACAM16",19,45202421,45213986,1,"protein_coding",388551,"CEACAM16",0.0295802581415047,-0.586640098,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000130202","PVRL2",19,45349432,45392485,1,"protein_coding",5819,"PVRL2",0.531937435077773,-0.314456223,3,6.844,0,"NA","NA","NA","NA","No","NA",{"v":4.8E-9,"d":"4.80E-09"},"rs429358;rs157580",36]
["ENSG00000130204","TOMM40",19,45393826,45406946,1,"protein_coding",10452,"TOMM40",0.963682323765023,"NA",13,12.64,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-21,"d":"2.60E-21"},"rs429358;rs157580;rs157595;rs157595:rs429358:rs9304644:rs190921611;rs2376867:rs57465754:rs190921611:19:45442062_CT_C:rs79429216:rs57465754;rs4803791",36]
["ENSG00000130203","APOE",19,45409011,45412650,1,"protein_coding",348,"APOE",0.0345335830833016,-0.237445173,15,12.64,1,{"v":4.00707e-05,"d":"4.01E-05"},0.0461303,"GTEx/v8/Pancreas","+","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-20,"d":"2.10E-20"},"rs157580;rs429358;rs157595;rs190921611;rs2376867;rs9304644:rs190921611:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000130208","APOC1",19,45417504,45422606,1,"protein_coding",341,"APOC1",0.0507382728810443,-0.105569458,24,12.64,3,{"v":3.55555e-06,"d":"3.56E-06"},0.00882724,"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs157580;rs429358;rs157595;rs5112;rs569925552;rs7246100;rs5112:rs5112;rs7246100:rs569925552:rs7246100:rs9304644:rs190921611;rs2376867:rs190921611:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000224916","APOC4-APOC2",19,45445495,45452822,1,"protein_coding",100533990,"APOC4-APOC2","NA","NA",89,17.4,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs7246100;rs190921611;rs9304644;rs2376867;19:45442062_CT_C;rs79429216;rs157580:rs429358:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100:rs7245887:rs145887105:rs4803791",36]
["ENSG00000267467","APOC4",19,45445495,45452820,1,"protein_coding",346,"APOC4",0.000150692347626422,0.337274035,89,17.4,111,{"v":4.4607e-14,"d":"4.46E-14"},{"v":3.56734e-09,"d":"3.57E-09"},"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs7246100;rs190921611;rs9304644;rs2376867;19:45442062_CT_C;rs79429216;rs57465754;rs7245887;rs4803791;rs157580:rs429358:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100:rs7245887:rs145887105:rs4803791",36]
["ENSG00000234906","APOC2",19,45449243,45452822,1,"protein_coding",344,"APOC2",0.0227961322934307,0.388732718,86,17.4,117,{"v":1.68804e-20,"d":"1.69E-20"},{"v":1.21381e-15,"d":"1.21E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs190921611;rs9304644;rs2376867;19:45442062_CT_C;rs79429216;rs4803791;rs5112;rs157580:rs429358:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100:rs7245887:rs145887105:rs4803791",36]
["ENSG00000267114","CTB-129P6.11",19,45453301,45457264,-1,"protein_coding","NA","NA","NA","NA",79,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs190921611;rs2376867;rs9304644;rs79429216;rs57465754;rs429358:rs157580:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100:rs9304644:rs190921611;rs2376867:rs190921611:rs57465754:rs57465754;rs4803791:rs7245887:rs145887105:rs4803791",36]
["ENSG00000104853","CLPTM1",19,45457842,45496599,1,"protein_coding",1209,"CLPTM1",0.98048307691788,"NA",121,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs9304644;rs190921611;rs2376867;rs57465754;rs4803791;rs79429216;rs429358:rs157580:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100:rs9304644:rs190921611;rs2376867:rs190921611:rs57465754:rs57465754;rs4803791:rs7245887:rs145887105:rs4803791",36]
["ENSG00000104856","RELB",19,45504688,45541452,1,"protein_coding",5971,"RELB",0.973562746007932,"NA",29,17.21,0,"NA","NA","NA","NA","No","NA",{"v":1e-17,"d":"1.00E-17"},"rs190921611;rs2376867;rs9304644;rs57465754;rs79429216;rs7245887;rs145887105;rs4803791",36]
["ENSG00000104859","CLASRP",19,45542298,45574214,1,"protein_coding",11129,"CLASRP",0.964966482147783,-0.085202503,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-27,"d":"1.10E-27"},"rs429358:rs157580:rs157595:rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100:rs9304644:rs190921611;rs2376867:rs57465754:rs190921611:rs57465754;rs4803791:rs7245887:rs145887105:rs4803791:19:45442062_CT_C:rs79429216",36]
["ENSG00000007255","TRAPPC6A",19,45666186,45681495,-1,"protein_coding",79090,"TRAPPC6A",0.000705277787371492,-0.133842318,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.6e-21,"d":"2.60E-21"},"rs429358:rs157595:rs9304644:rs190921611;rs2376867:rs57465754:rs190921611:rs57465754;rs4803791",36]
["ENSG00000189114","BLOC1S3",19,45682003,45685059,1,"protein_coding",388552,"BLOC1S3",0.0184297702580611,-0.115773028,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.6e-21,"d":"2.60E-21"},"rs429358:rs157595:rs9304644:rs190921611;rs2376867:rs57465754:rs190921611:rs57465754;rs4803791",36]
["ENSG00000267545","AC005779.2",19,45683080,45705702,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.6e-21,"d":"2.60E-21"},"rs429358:rs157595:rs9304644:rs190921611;rs2376867:rs57465754:rs190921611:rs57465754;rs4803791",36]
["ENSG00000266958","AC006126.3",19,45690646,45720191,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Promoter_anchored_loops",{"v":5.7e-12,"d":"5.70E-12"},"rs9304644:rs190921611;rs2376867",36]
["ENSG00000130201","EXOC3L2",19,45715879,45737469,-1,"protein_coding",90332,"EXOC3L2",0.925564031557031,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791:rs7245887:rs145887105:rs4803791",36]
["ENSG00000104879","CKM",19,45809672,45826235,-1,"protein_coding",1158,"CKM",0.00505058616928749,0.03849229,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791:rs7245887:rs145887105:rs4803791",36]
["ENSG00000104892","KLC3",19,45836692,45854778,1,"protein_coding",147700,"KLC3",{"v":3.15849310261577e-06,"d":"3.16E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791:rs7245887:rs145887105:rs4803791",36]
["ENSG00000268341","L47234.1",19,45842445,45842639,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000104884","ERCC2",19,45853095,45874176,-1,"protein_coding",2068,"ERCC2",{"v":3.14163491830693e-13,"d":"3.14E-13"},-0.123245341,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.4e-19,"d":"2.40E-19"},"rs190921611:rs9304644:rs190921611;rs2376867:19:45442062_CT_C:rs79429216:rs57465754:rs57465754;rs4803791",36]
["ENSG00000125746","EML2",19,46110252,46148887,-1,"protein_coding",24139,"EML2",{"v":7.57699496433696e-10,"d":"7.58E-10"},0.190257397,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":9.5e-18,"d":"9.50E-18"},"rs190921611;rs2376867:rs9304644:rs190921611;rs9304644;rs2376867:rs9304644;rs2376867:rs57465754:rs2376867:rs79429216",36]
["ENSG00000267757","C19orf83",19,46144752,46146098,1,"protein_coding",100287177,"C19orf83","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":9.5e-18,"d":"9.50E-18"},"rs190921611;rs2376867:rs9304644:rs190921611;rs9304644;rs2376867:rs9304644;rs2376867:rs57465754:rs2376867:rs79429216",36]
["ENSG00000104941","RSPH6A",19,46298968,46318577,-1,"protein_coding",81492,"RSPH6A",{"v":2.54884442731765e-08,"d":"2.55E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-27,"d":"1.10E-27"},"rs5112:rs5112;rs569925552;rs7246100:rs569925552:rs7246100",36]
["ENSG00000101442","ACTR5",20,37377085,37400834,1,"protein_coding",79913,"ACTR5",{"v":1.00014232070039E-12,"d":"1.00E-12"},0.539172179,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7.6e-09,"d":"7.60E-09"},"rs6129624",37]
["ENSG00000101452","DHX35",20,37590942,37668366,1,"protein_coding",60625,"DHX35",{"v":9.69273790916275e-11,"d":"9.69E-11"},-0.629421294,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":9.3e-09,"d":"9.30E-09"},"rs6129624",37]
["ENSG00000204103","MAFB",20,39314488,39317880,-1,"protein_coding",9935,"MAFB","NA",-1.167100522,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs6129624",37]
["ENSG00000159259","CHAF1B",21,37757676,37791313,1,"protein_coding",8208,"CHAF1B",0.536697059074058,-0.160409705,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.8e-09,"d":"3.80E-09"},"rs4818005:rs117143374",38]
["ENSG00000159261","CLDN14",21,37832919,37948867,-1,"protein_coding",23562,"CLDN14",0.000330686692861074,-0.047663046,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000185808","PIGP",21,38431470,38445470,-1,"protein_coding",51227,"PIGP",0.000394928585804372,-0.013169922,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000182670","TTC3",21,38445526,38575413,1,"protein_coding",7267,"TTC3",{"v":5.39422630787731e-20,"d":"5.39E-20"},2.594090473,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157538","DSCR3",21,38595721,38640262,-1,"protein_coding",10311,"DSCR3",0.50591897208566,-0.574889328,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157540","DYRK1A",21,38738092,38889753,1,"protein_coding",1859,"DYRK1A",0.999584541726647,-0.189242879,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157542","KCNJ6",21,38979678,39288749,-1,"protein_coding",3763,"KCNJ6",0.812451385393419,-0.293776228,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000184029","DSCR4",21,39323728,39493454,-1,"protein_coding",10281,"DSCR4",1.31700519306661E-3,-0.302470392,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000198054","DSCR8",21,39493545,39560110,1,"protein_coding",84677,"DSCR8","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157551","KCNJ15",21,39529128,39679279,1,"protein_coding",3772,"KCNJ15",0.15046203852881,-0.034461656,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157554","ERG",21,39751949,40033704,-1,"protein_coding",2078,"ERG",0.968344473919641,-1.0284408,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157557","ETS2",21,40177231,40196879,1,"protein_coding",2114,"ETS2",0.993350130351238,-0.120506267,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Bladder:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000183527","PSMG1",21,40546695,40555777,-1,"protein_coding",8624,"PSMG1",0.0129744173088997,1.390731051,65,17.49,287,{"v":8.94604e-54,"d":"8.95E-54"},{"v":7.31801e-46,"d":"7.32E-46"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005;rs117143374;rs4818005:rs117143374",38]
["ENSG00000185658","BRWD1",21,40556102,40693485,-1,"protein_coding",54014,"BRWD1",0.999999462325348,-0.105449763,235,23.6,209,{"v":6.51459e-09,"d":"6.51E-09"},{"v":5.7693e-05,"d":"5.77E-05"},"GTEx/v8/Pancreas","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005;rs117143374;rs4818005:rs117143374",38]
["ENSG00000205581","HMGN1",21,40714241,40721573,-1,"protein_coding",3150,"HMGN1",0.425365462309957,"NA",13,7.084,53,{"v":9.89783e-07,"d":"9.90E-07"},0.00446302,"GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs4818005;rs117143374;rs4818005:rs117143374",38]
["ENSG00000182093","WRB",21,40752170,40800454,1,"protein_coding",7485,"WRB",0.0591591068672799,-0.294767908,0,0,201,{"v":5.20372e-19,"d":"5.20E-19"},{"v":2.49782e-110,"d":"2.50E-110"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005;rs117143374;rs4818005:rs117143374",38]
["ENSG00000157578","LCA5L",21,40777770,40817731,-1,"protein_coding",150082,"LCA5L",{"v":1.90936191141484e-06,"d":"1.91E-06"},-0.119104428,0,0,8,{"v":6.59823e-10,"d":"6.60E-10"},{"v":6.39662e-59,"d":"6.40E-59"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs117143374;rs4818005:rs117143374",38]
["ENSG00000185437","SH3BGR",21,40817781,40887433,1,"protein_coding",6450,"SH3BGR",0.00035235304533994,-0.071424958,0,0,225,{"v":3.546e-14,"d":"3.55E-14"},{"v":6.77952e-44,"d":"6.78E-44"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005;rs117143374;rs4818005:rs117143374",38]
["ENSG00000184809","C21orf88",21,40969074,40984748,-1,"protein_coding",114041,"C21orf88","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":2.2e-10,"d":"2.20E-10"},"rs4818005:rs117143374",38]
["ENSG00000157600","TMEM164",23,109245859,109425962,1,"protein_coding",84187,"TMEM164",0.877400449225457,-2.007872381,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.2e-14,"d":"6.20E-14"},"rs200991074",39]
["ENSG00000101935","AMMECR1",23,109437414,109683461,-1,"protein_coding",9949,"AMMECR1",0.910792997313756,-2.109243506,7,13.98,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":6.2e-14,"d":"6.20E-14"},"rs200991074",39]
["ENSG00000243978","RGAG1",23,109602044,109699562,1,"protein_coding",57529,"RGAG1",0.912655333274139,0.494918933,22,13.98,376,{"v":3.01409e-06,"d":"3.01E-06"},0.00335742,"GTEx/v8/Heart_Atrial_Appendage","-","No","NA",{"v":6.2e-14,"d":"6.20E-14"},"rs200991074",39]
["ENSG00000101938","CHRDL1",23,109917084,110039286,-1,"protein_coding",91851,"CHRDL1",0.0536284936083553,"NA",77,16.15,392,{"v":7.97604e-50,"d":"7.98E-50"},{"v":1.32344E-42,"d":"1.32E-42"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","No","NA",{"v":6.2e-14,"d":"6.20E-14"},"rs200991074",39]
["ENSG00000077279","DCX",23,110537007,110655603,-1,"protein_coding",1641,"DCX",0.863196407367064,-3.566269335,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":6.2e-12,"d":"6.20E-12"},"rs200991074",39]
["ENSG00000187823","ZCCHC16",23,111697727,111700473,1,"protein_coding",340595,"ZCCHC16",0.000561724706329207,1.180700486,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":6.2e-14,"d":"6.20E-14"},"rs200991074",39]

{"sheet":"ST4C","index":6,"n_rows":1127,"n_cols":23,"rows_kept":1127}
["ensg","symbol","chr","start","end","strand","type","entrezID","HUGO","pLI","ncRVIS","posMapSNPs","posMapMaxCADD","eqtlMapSNPs","eqtlMapminP","eqtlMapminQ","eqtlMapts","eqtlDirection","ciMap","ciMapts","minGwasP","IndSigSNPs","GenomicLocus"]
["ENSG00000173372","C1QA",1,22962999,22966101,1,"protein_coding",712,"C1QA",0.0497899792321254,0.221836438,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":8.5e-08,"d":"8.50E-08"},"rs534417",1]
["ENSG00000159189","C1QC",1,22970123,22974603,1,"protein_coding",714,"C1QC",0.0173819025149602,0.719487547,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":8.5e-08,"d":"8.50E-08"},"rs534417",1]
["ENSG00000173369","C1QB",1,22979255,22988031,1,"protein_coding",713,"C1QB",0.0858810485832231,0.026532976,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":8.5e-08,"d":"8.50E-08"},"rs534417",1]
["ENSG00000125944","HNRNPR",1,23630264,23670829,-1,"protein_coding",10236,"HNRNPR",0.999079074304417,-0.733548061,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.2e-08,"d":"5.20E-08"},"rs534417",1]
["ENSG00000125945","ZNF436",1,23685941,23695935,-1,"protein_coding",80818,"ZNF436",0.304488387158864,-0.229845222,0,0,21,{"v":9.86385E-7,"d":"9.86E-07"},{"v":3.86751e-44,"d":"3.87E-44"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","IMR90",{"v":3.7E-9,"d":"3.70E-09"},"rs534417",1]
["ENSG00000249087","C1orf213",1,23695490,23698332,1,"protein_coding",148898,"C1orf213",2.60771141851481E-4,"NA",0,0,21,{"v":2.56657e-07,"d":"2.57E-07"},{"v":4.16168e-42,"d":"4.16E-42"},"GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","-","Yes","IMR90",{"v":3.7E-9,"d":"3.70E-09"},"rs534417",1]
["ENSG00000204219","TCEA3",1,23707554,23751233,-1,"protein_coding",6920,"TCEA3",0.000965885853095805,"NA",21,13.85,44,{"v":1.56531e-11,"d":"1.57E-11"},{"v":1.85952e-17,"d":"1.86E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","IMR90",{"v":3.7E-9,"d":"3.70E-09"},"rs534417",1]
["ENSG00000088280","ASAP3",1,23755056,23811061,-1,"protein_coding",55616,"ASAP3",{"v":2.35907220968951e-10,"d":"2.36E-10"},-0.119098762,55,13.85,50,{"v":4.59736e-16,"d":"4.60E-16"},{"v":1.28343E-23,"d":"1.28E-23"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:IMR90",{"v":3.7E-9,"d":"3.70E-09"},"rs534417",1]
["ENSG00000007968","E2F2",1,23832922,23857712,-1,"protein_coding",1870,"E2F2",0.914702778499156,-0.034311204,1,1.595,13,{"v":4.18331e-06,"d":"4.18E-06"},0.00318171,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops:Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":5.2e-08,"d":"5.20E-08"},"rs534417",1]
["ENSG00000117318","ID3",1,23884409,23886285,-1,"protein_coding",3399,"ID3",0.68879433753555,-0.270653991,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.5e-08,"d":"8.50E-08"},"rs534417:rs2986164;rs548179580:rs548179580","01:02:00"]
["ENSG00000197880","MDS2",1,23907985,23967058,1,"protein_coding",259283,"MDS2",0.0429655728784688,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.5e-08,"d":"8.50E-08"},"rs2986164;rs548179580:rs548179580:rs534417","01:02:00"]
["ENSG00000142676","RPL11",1,24018269,24022915,1,"protein_coding",6135,"RPL11",0.725843320629066,0.111094014,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.7E-9,"d":"3.70E-09"},"rs534417",1]
["ENSG00000057757","PITHD1",1,24104895,24114722,1,"protein_coding",57095,"PITHD1",0.102416722752494,-0.424805415,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell",{"v":8.5e-08,"d":"8.50E-08"},"rs534417",1]
["ENSG00000011009","LYPLA2",1,24117460,24122029,1,"protein_coding",11313,"LYPLA2",0.979519145027567,-0.992130873,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:Mesenchymal_Stem_Cell",{"v":8.5e-08,"d":"8.50E-08"},"rs534417",1]
["ENSG00000117602","RCAN3",1,24829387,24867530,1,"protein_coding",11123,"RCAN3",0.00320642195331169,1.106938656,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3e-08,"d":"3.00E-08"},"rs2986164;rs548179580",2]
["ENSG00000133226","SRRM1",1,24958207,24999758,1,"protein_coding",10250,"SRRM1",0.999999022390233,-0.322831857,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580",2]
["ENSG00000169504","CLIC4",1,25071848,25170815,1,"protein_coding",25932,"CLIC4",0.00946200366501209,-1.236427948,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3e-08,"d":"3.00E-08"},"rs2986164;rs548179580",2]
["ENSG00000117614","SYF2",1,25549170,25558993,-1,"protein_coding",25949,"SYF2",0.0379270965280319,-0.019645579,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000117616","C1orf63",1,25568728,25664704,-1,"protein_coding",57035,"C1orf63",{"v":2.72287500037132e-08,"d":"2.72E-08"},-0.47340473,10,6.636,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.7e-09,"d":"1.70E-09"},"rs2986164;rs548179580;rs548179580:rs548179580",2]
["ENSG00000187010","RHD",1,25598884,25656936,1,"protein_coding",6007,"RHD",0.00606009991775824,0.419810588,5,6.636,180,{"v":6.63088e-50,"d":"6.63E-50"},{"v":4.59706e-106,"d":"4.60E-106"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":1.7e-09,"d":"1.70E-09"},"rs2986164;rs548179580;rs2986164:rs2986164",2]
["ENSG00000183726","TMEM50A",1,25664408,25688852,1,"protein_coding",23585,"TMEM50A",0.333486481175581,-0.802493983,16,9.801,180,{"v":6.66978e-13,"d":"6.67E-13"},{"v":3.27318e-22,"d":"3.27E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580;rs548179580:rs548179580",2]
["ENSG00000188672","RHCE",1,25688740,25756683,-1,"protein_coding",6006,"RHCE",0.861454126246099,0.078594887,92,13.31,180,{"v":5.93595e-36,"d":"5.94E-36"},{"v":1.30902E-29,"d":"1.31E-29"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580;rs548179580:rs548179580",2]
["ENSG00000204178","TMEM57",1,25757388,25826700,1,"protein_coding",55219,"TMEM57",0.992504411290221,1.055454968,117,15.98,180,{"v":8.27856e-16,"d":"8.28E-16"},{"v":2.13504e-11,"d":"2.14E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580;rs548179580:rs548179580",2]
["ENSG00000157978","LDLRAP1",1,25870071,25895377,1,"protein_coding",26119,"LDLRAP1",{"v":2.90076895064709e-05,"d":"2.90E-05"},-0.605728099,4,2.099,1,{"v":4.80051e-05,"d":"4.80E-05"},{"v":2.7201e-11,"d":"2.72E-11"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580;rs548179580:rs548179580",2]
["ENSG00000117643","MAN1C1",1,25943959,26112698,1,"protein_coding",57134,"MAN1C1",0.0490480402547963,0.898505667,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000162430","SEPN1",1,26126667,26144713,1,"protein_coding",57190,"SEPN1",{"v":1.08497392205754e-07,"d":"1.08E-07"},-0.14036306,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-08,"d":"1.10E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000255054","RP1-317E23.6",1,26137961,26150235,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1E-8,"d":"1.00E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000117640","MTFR1L",1,26145131,26159432,1,"protein_coding",56181,"MTFR1L",0.431750877541367,0.035573706,0,0,14,{"v":3.11664E-5,"d":"3.12E-05"},{"v":1.5749E-37,"d":"1.57E-37"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-08,"d":"1.10E-08"},"rs2986164;rs548179580;rs548179580:rs548179580",2]
["ENSG00000223474","AL020996.1",1,26145212,26147288,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-08,"d":"1.10E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000127423","AUNIP",1,26158414,26185903,-1,"protein_coding",79000,"AUNIP",{"v":5.49329871865606E-8,"d":"5.49E-08"},0.668522621,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7e-09,"d":"1.70E-09"},"rs2986164:rs2986164;rs548179580:rs548179580",2]
["ENSG00000182749","PAQR7",1,26187701,26197744,-1,"protein_coding",164091,"PAQR7",0.0093107679780527,0.742661414,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8e-08,"d":"1.80E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000117632","STMN1",1,26210672,26233482,-1,"protein_coding",3925,"STMN1",0.648591503545553,-0.336099456,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":1.1e-08,"d":"1.10E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000158006","PAFAH2",1,26286258,26324648,-1,"protein_coding",5051,"PAFAH2",{"v":2.68539651867445e-07,"d":"2.69E-07"},-0.682015872,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.7e-09,"d":"1.70E-09"},"rs2986164:rs2986164;rs548179580:rs548179580",2]
["ENSG00000158008","EXTL1",1,26346375,26362955,1,"protein_coding",2134,"EXTL1",{"v":1.17897567862766E-12,"d":"1.18E-12"},-0.545045167,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-08,"d":"1.80E-08"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000197245","FAM110D",1,26485511,26489119,1,"protein_coding",79927,"FAM110D",0.550404227081523,-0.050060073,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.4E-8,"d":"3.40E-08"},"rs2986164;rs548179580",2]
["ENSG00000142675","CNKSR1",1,26503894,26516377,1,"protein_coding",10256,"CNKSR1",{"v":3.79048704121579e-16,"d":"3.79E-16"},-0.156165951,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.9e-07,"d":"2.90E-07"},"rs2986164;rs548179580",2]
["ENSG00000130695","CEP85",1,26560691,26605299,1,"protein_coding",64793,"CEP85",0.00585126875456993,-0.28245067,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.3E-7,"d":"1.30E-07"},"rs2986164;rs548179580:rs548179580",2]
["ENSG00000142669","SH3BGRL3",1,26605667,26608007,1,"protein_coding",83442,"SH3BGRL3",0.795103829065415,-0.629466622,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3e-08,"d":"3.00E-08"},"rs2986164;rs548179580",2]
["ENSG00000116209","TMEM59",1,54497347,54519177,-1,"protein_coding",9528,"TMEM59",{"v":2.23025067852854E-7,"d":"2.23E-07"},0.206649282,0,0,1,{"v":2.03947E-5,"d":"2.04E-05"},1.96452E-3,"GTEx/v8/Artery_Aorta","+","No","NA",{"v":3.1E-24,"d":"3.10E-24"},"rs11591147",3]
["ENSG00000169174","PCSK9",1,55505221,55530525,1,"protein_coding",255738,"PCSK9",{"v":1.02507611210468E-10,"d":"1.03E-10"},0.264270736,5,15.41,7,{"v":2.27824e-14,"d":"2.28E-14"},{"v":8.14778E-23,"d":"8.15E-23"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial","+","No","NA",{"v":3.1E-24,"d":"3.10E-24"},"rs11206510;rs11591147;rs12067569;rs34232196",3]
["ENSG00000162402","USP24",1,55532032,55680786,-1,"protein_coding",23358,"USP24",0.999999998496473,-1.006094649,27,15.23,2,{"v":9.28051e-05,"d":"9.28E-05"},{"v":2.70552E-9,"d":"2.71E-09"},"GTEx/v8/Artery_Tibial","-","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs12067569",3]
["ENSG00000162407","PPAP2B",1,56960419,57110974,-1,"protein_coding",8613,"PPAP2B",0.961834123262929,-0.049380558,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs12067569",3]
["ENSG00000162409","PRKAA2",1,57110995,57181008,1,"protein_coding",5563,"PRKAA2",{"v":1.44261719898224E-5,"d":"1.44E-05"},-1.053997381,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs12067569",3]
["ENSG00000187889","C1orf168",1,57184477,57285369,-1,"protein_coding",199920,"C1orf168",{"v":2.35652055532321e-30,"d":"2.36E-30"},-0.300645978,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs12067569",3]
["ENSG00000157131","C8A",1,57320479,57383894,1,"protein_coding",731,"C8A",{"v":5.355640730752E-11,"d":"5.36E-11"},0.184569853,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs12067569",3]
["ENSG00000021852","C8B",1,57394883,57431813,-1,"protein_coding",732,"C8B",{"v":1.49406934497858E-9,"d":"1.49E-09"},0.183539069,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5e-08,"d":"5.00E-08"},"rs12067569",3]
["ENSG00000134709","HOOK1",1,60280458,60342050,1,"protein_coding",51361,"HOOK1",{"v":4.15670073195207e-05,"d":"4.16E-05"},-0.06279745,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":3.1E-93,"d":"3.10E-93"},"1:62980399_CACA_C:rs1183851;rs1168100:rs912540;rs536629310:1:62980399_CACA_C;rs6661669:1:63179919_AAG_A:1:63183414_CCA_C:rs76272805:rs578078376:rs10458569:rs77449055:rs373836691:rs1183851",4]
["ENSG00000134716","CYP2J2",1,60358980,60392462,-1,"protein_coding",1573,"CYP2J2",{"v":4.51201698997771e-12,"d":"4.51E-12"},0.320327764,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.4E-15,"d":"3.40E-15"},"rs7518009:rs35837000:rs76272805:rs6587973:rs138704976:1:63179919_AAG_A",4]
["ENSG00000162599","NFIA",1,61330931,61928465,1,"protein_coding",4774,"NFIA",0.999555166212873,-0.180372327,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-18,"d":"1.40E-18"},"rs6587973:rs12044009:rs138704976:rs72929768:rs77449055",4]
["ENSG00000132854","KANK4",1,62702651,62785085,-1,"protein_coding",163782,"KANK4",{"v":5.3984986278488e-08,"d":"5.40E-08"},-0.458433659,0,0,2,{"v":1.23552E-5,"d":"1.24E-05"},{"v":9.06934e-05,"d":"9.07E-05"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-18,"d":"1.40E-18"},"rs72929768;rs7518009:rs35837000:rs76272805:rs6587973:rs138704976:1:63179919_AAG_A:rs12044009:rs72929768",4]
["ENSG00000162607","USP1",1,62901968,62917475,1,"protein_coding",7398,"USP1",0.993180568281562,-1.542076225,56,18.26,10,{"v":1.97043E-7,"d":"1.97E-07"},4.32786E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8E-93,"d":"2.80E-93"},"1:63183414_CCA_C;1:62980399_CACA_C;rs6661669;rs1183851;rs578078376;1:63179919_AAG_A;rs912540;rs536629310;rs10458569;rs72929768;rs1168100;rs2149116;rs7533354;rs55954926:rs34289527;rs7512480:rs549889612:1:62980399_CACA_C;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs1183851;rs1168100:1:63179919_AAG_A:rs76272805:rs374131620:rs1183851;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs12044009:rs12122434:1:63268136_TA_T:rs34289527:1:63045366_GA_G",4]
["ENSG00000116641","DOCK7",1,62920399,63153969,-1,"protein_coding",85440,"DOCK7",0.771361085896655,"NA",330,18.64,561,{"v":1.09201E-20,"d":"1.09E-20"},{"v":9.93875E-16,"d":"9.94E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.2e-93,"d":"1.20E-93"},"1:63179919_AAG_A;1:62980399_CACA_C;rs6661669;rs578078376;rs912540;rs536629310;rs10458569;1:63183414_CCA_C;rs77449055;rs373836691;rs1183851;rs55853774;rs17381383;rs1168100;rs76272805;1:63045366_GA_G;rs12044009;1:63130453_TA_T;1:63131385_CAA_C;1:63134595_CA_C;1:63149883_TA_T;rs183409343;1:63203399_AT_A;rs72929768;rs2149116;rs7533354;rs55954926;rs12124310;rs61765938;rs34289527;rs7512480;rs12122434;1:63190449_GTTTTTTTT_G:rs912540:1:63203399_AT_A:rs6661669:rs2149116:1:62980399_CACA_C;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs76272805:1:63045366_GA_G:rs12044009:1:63179919_AAG_A:rs1183851",4]
["ENSG00000132855","ANGPTL3",1,63063158,63071830,1,"protein_coding",27329,"ANGPTL3",{"v":2.12015609401708e-07,"d":"2.12E-07"},-0.803837249,20,12.12,15,{"v":1.13102e-05,"d":"1.13E-05"},0.0421505,"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-93,"d":"1.20E-93"},"1:63183414_CCA_C;1:62980399_CACA_C;rs12044009;1:63179919_AAG_A;rs6661669;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs1183851;rs1168100:1:63179919_AAG_A:rs76272805:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs536629310:rs17381383:rs1168100:rs55853774:1:63130453_TA_T:1:63131385_CAA_C:1:63134595_CA_C:1:63149883_TA_T:rs183409343:rs72929768:rs116316096:rs912540;1:63203399_AT_A:rs7533354;rs55954926:rs7533354:rs34289527:rs12124310:rs61765938:rs34289527;rs7512480:rs12044009:rs549889612:rs12122434:1:63268136_TA_T:rs55954926:rs34289527;rs7533354;rs7512480;rs55954926:rs7512480",4]
["ENSG00000269624","AL138847.1",1,63073437,63075249,1,"protein_coding","NA","NA","NA","NA",14,12.12,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-93,"d":"1.20E-93"},"1:63179919_AAG_A;1:62980399_CACA_C;rs12044009;rs1183851;rs1168100;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs1183851;rs1168100:1:63179919_AAG_A:rs76272805:rs374131620:rs1183851;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs536629310:rs17381383:rs1168100:rs55853774:1:63130453_TA_T:1:63131385_CAA_C:1:63134595_CA_C:1:63149883_TA_T:rs183409343:rs72929768:rs116316096:rs912540;1:63203399_AT_A:rs7533354;rs55954926:rs7533354:rs34289527:rs12124310:rs61765938:rs34289527;rs7512480:rs12044009:rs549889612:rs12122434:1:63268136_TA_T:rs55954926:rs34289527;rs7533354;rs7512480;rs55954926:rs7512480",4]
["ENSG00000125703","ATG4C",1,63249806,63331184,1,"protein_coding",84938,"ATG4C",{"v":3.32761781234443e-09,"d":"3.33E-09"},-0.809376853,170,17.7,150,{"v":6.89586e-06,"d":"6.90E-06"},0.00836476,"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2e-93,"d":"1.20E-93"},"rs7533354;rs55954926;rs12044009;rs34289527;rs7512480;rs549889612;rs12122434;1:63268136_TA_T;rs12124310;rs61765938;rs77449055;1:62980399_CACA_C:1:62980399_CACA_C;rs6661669:rs1183851:rs578078376:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs373836691:rs72929768:rs116316096:1:63179919_AAG_A:rs536629310:rs17381383:rs1168100:rs76272805:1:63045366_GA_G:rs12044009:rs1183851;rs1168100:rs55853774:rs912540",4]
["ENSG00000187140","FOXD3",1,63788730,63790797,1,"protein_coding",27022,"FOXD3","NA",-0.433105976,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.5e-07,"d":"5.50E-07"},"rs77449055",4]
["ENSG00000088035","ALG6",1,63833261,63904233,1,"protein_coding",29929,"ALG6",0.0553676261725129,-0.307102505,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.1e-23,"d":"2.10E-23"},"rs77449055:rs34289527;rs7512480:rs12124310:rs7533354;rs55954926:rs34289527:rs7533354:rs7512480",4]
["ENSG00000142856","ITGB3BP",1,63906441,64059392,-1,"protein_coding",23421,"ITGB3BP",{"v":1.47054021720334E-5,"d":"1.47E-05"},-0.391812829,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":5.5e-07,"d":"5.50E-07"},"rs77449055",4]
["ENSG00000203965","EFCAB7",1,63989043,64038364,1,"protein_coding",84455,"EFCAB7",{"v":1.67071925383672e-12,"d":"1.67E-12"},-0.503488032,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.2e-93,"d":"1.20E-93"},"rs77449055:rs6587973:rs12044009:rs138704976:rs72929768:rs116316096:1:63183414_CCA_C:1:62980399_CACA_C:1:62980399_CACA_C;rs6661669:rs1183851:rs578078376:1:63179919_AAG_A:rs912540;rs536629310:rs10458569:rs373836691:rs34289527;rs7512480:rs12124310:rs7533354;rs55954926:rs61765938:rs55954926:rs34289527:rs34289527;rs7533354;rs7512480;rs55954926:rs7533354:rs7512480:rs76272805:1:63045366_GA_G:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs549889612:rs12122434:1:63268136_TA_T:rs55853774:rs17381383:rs1183851",4]
["ENSG00000116652","DLEU2L",1,64014588,64015405,1,"protein_coding",79469,"DLEU2L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-93,"d":"2.30E-93"},"1:62980399_CACA_C;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs34289527;rs7512480:rs12124310:rs7533354;rs55954926:rs34289527:rs7533354:rs7512480:rs61765938:rs55954926:rs34289527;rs7533354;rs7512480;rs55954926:rs549889612:rs12044009:rs12122434:1:63268136_TA_T:rs536629310:rs17381383:1:63179919_AAG_A:rs1168100:rs1183851;rs1168100:rs76272805:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116",4]
["ENSG00000079739","PGM1",1,64058947,64125916,1,"protein_coding",5236,"PGM1",{"v":9.96139807231456e-06,"d":"9.96E-06"},1.203178507,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":5.5e-07,"d":"5.50E-07"},"rs77449055",4]
["ENSG00000158966","CACHD1",1,64936428,65158741,1,"protein_coding",57685,"CACHD1",0.838036969203847,0.056390161,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.5e-07,"d":"5.50E-07"},"rs77449055",4]
["ENSG00000162437","RAVER2",1,65210778,65298915,1,"protein_coding",55225,"RAVER2",{"v":1.85996394365043E-6,"d":"1.86E-06"},-0.746777186,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-93,"d":"2.30E-93"},"1:62980399_CACA_C:1:63183414_CCA_C:rs77449055:rs536629310:rs17381383:rs578078376:1:63179919_AAG_A:rs1168100:rs912540;rs536629310:rs6587973:rs12044009:rs138704976:rs72929768:rs34289527;rs7512480:rs12124310:rs7533354;rs55954926:rs34289527:rs7533354:rs7512480:rs76272805:1:63045366_GA_G:1:62980399_CACA_C;rs6661669:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs61765938:rs55954926:rs34289527;rs7533354;rs7512480;rs55954926",4]
["ENSG00000116675","DNAJC6",1,65713902,65881552,1,"protein_coding",9829,"DNAJC6",0.99918835079312,-0.584518275,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":5.5e-07,"d":"5.50E-07"},"rs77449055",4]
["ENSG00000121957","GPSM2",1,109417972,109477167,1,"protein_coding",29899,"GPSM2",{"v":2.9412972070079e-10,"d":"2.94E-10"},0.141117521,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway",{"v":1.4e-09,"d":"1.40E-09"},"rs6657811;rs35271870",5]
["ENSG00000085433","WDR47",1,109512836,109584850,-1,"protein_coding",22911,"WDR47",0.90566161819711,-0.351230971,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-10,"d":"1.90E-10"},"rs6657811;rs35271870:rs35271870:rs1337248",5]
["ENSG00000197780","TAF13",1,109605108,109618624,-1,"protein_coding",6884,"TAF13",0.0198501953204612,0.249428817,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-10,"d":"1.90E-10"},"rs35271870:rs1337248",5]
["ENSG00000215717","TMEM167B",1,109632425,109639556,1,"protein_coding",56900,"TMEM167B",0.632476718728509,-0.038371693,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-10,"d":"1.90E-10"},"rs35271870:rs1337248",5]
["ENSG00000179902","C1orf194",1,109648573,109656479,-1,"protein_coding",127003,"C1orf194",{"v":2.50029511352176e-07,"d":"2.50E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-10,"d":"1.90E-10"},"rs6657811;rs35271870:rs35271870:rs1337248",5]
["ENSG00000116299","KIAA1324",1,109656301,109749401,1,"protein_coding",57535,"KIAA1324",{"v":2.14864520738644E-8,"d":"2.15E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-10,"d":"1.90E-10"},"rs6657811;rs35271870:rs35271870:rs1337248",5]
["ENSG00000031698","SARS",1,109756540,109780791,1,"protein_coding",6301,"SARS",0.999150650957633,-0.332037527,1,5.364,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-27,"d":"2.10E-27"},"rs35271870;rs35271870:rs1337248:rs3832016:rs611917:rs68104325",5]
["ENSG00000143126","CELSR2",1,109792641,109818372,1,"protein_coding",1952,"CELSR2",0.999999199832348,0.807304437,32,18.47,31,{"v":9.42742e-34,"d":"9.43E-34"},{"v":2.20583e-27,"d":"2.21E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen",{"v":1.5e-27,"d":"1.50E-27"},"rs1337248;rs6657811;rs35271870;1:109809343_CT_C;rs3832016;rs611917;rs68104325;rs35271870:rs3832016:rs611917:rs68104325:rs6657811;rs35271870:rs1337248:rs6657811:1:109809343_CT_C",5]
["ENSG00000134222","PSRC1",1,109822178,109825808,-1,"protein_coding",84722,"PSRC1",{"v":1.74717788563073e-06,"d":"1.75E-06"},-0.208880013,22,18.47,26,{"v":1.0541E-37,"d":"1.05E-37"},{"v":1.834e-30,"d":"1.83E-30"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Spleen",{"v":1.5e-27,"d":"1.50E-27"},"rs3832016;rs611917;rs35271870;rs68104325;rs6657811;rs1337248:rs35271870",5]
["ENSG00000221986","MYBPHL",1,109834987,109849663,-1,"protein_coding",343263,"MYBPHL",0.00461844098878081,0.281706372,2,12.97,0,"NA","NA","NA","NA","Yes","EP_links_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-12,"d":"4.40E-12"},"rs68104325;rs6657811;rs35271870:rs35271870:rs1337248",5]
["ENSG00000134243","SORT1",1,109852192,109940573,-1,"protein_coding",6272,"SORT1",0.999926560036891,-1.346190944,0,0,28,{"v":3.08634e-54,"d":"3.09E-54"},{"v":3.21918e-45,"d":"3.22E-45"},"GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-27,"d":"1.50E-27"},"rs35271870;rs1337248;rs6657811;rs3832016;rs611917;rs68104325;rs1337248:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs35271870:rs3832016:rs611917:rs68104325",5]
["ENSG00000143106","PSMA5",1,109941653,109969062,-1,"protein_coding",5686,"PSMA5",0.974255885097096,-1.084093805,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":1.9e-10,"d":"1.90E-10"},"rs35271870:rs1337248",5]
["ENSG00000143028","SYPL2",1,110009180,110024759,1,"protein_coding",284612,"SYPL2",0.0167710987562036,0.437866135,0,0,21,{"v":1.20726E-11,"d":"1.21E-11"},{"v":1.41445e-54,"d":"1.41E-54"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver","+","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-27,"d":"1.50E-27"},"rs35271870;rs6657811;rs3832016;rs68104325;rs611917;rs35271870:rs1337248:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs3832016:rs611917:rs68104325",5]
["ENSG00000162650","ATXN7L2",1,110026101,110035426,1,"protein_coding",127002,"ATXN7L2",0.718954812432385,"NA",0,0,13,{"v":5.83014e-07,"d":"5.83E-07"},{"v":6.65426e-17,"d":"6.65E-17"},"GTEx/v8/Liver","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-27,"d":"1.50E-27"},"rs611917;rs3832016;rs1337248:rs35271870:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs3832016:rs611917:rs68104325",5]
["ENSG00000174151","CYB561D1",1,110036674,110045554,1,"protein_coding",284613,"CYB561D1",0.0158304191038284,-0.395994268,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-27,"d":"1.50E-27"},"rs35271870:rs1337248:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs3832016:rs611917:rs68104325",5]
["ENSG00000181754","AMIGO1",1,110046797,110052360,-1,"protein_coding",57463,"AMIGO1",0.888492588974354,-0.212526248,0,0,1,{"v":3.44259e-05,"d":"3.44E-05"},{"v":8.72509e-57,"d":"8.73E-57"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":8.9e-14,"d":"8.90E-14"},"rs68104325;rs6657811;rs35271870:rs1337248:rs6657811:1:109809343_CT_C:rs35271870",5]
["ENSG00000156097","GPR61",1,110082494,110091028,1,"protein_coding",83873,"GPR61",0.801488898268086,-0.586870154,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":8.9e-14,"d":"8.90E-14"},"rs6657811;rs35271870:rs1337248:rs6657811:1:109809343_CT_C:rs35271870",5]
["ENSG00000065135","GNAI3",1,110091233,110136975,1,"protein_coding",2773,"GNAI3",0.038811277618943,0.458884037,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-10,"d":"1.90E-10"},"rs35271870:rs1337248",5]
["ENSG00000168765","GSTM4",1,110198703,110208118,1,"protein_coding",2948,"GSTM4",0.000917344712640999,0.373951732,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.9e-10,"d":"1.90E-10"},"rs35271870:rs1337248",5]
["ENSG00000134184","GSTM1",1,110230436,110251661,1,"protein_coding",2944,"GSTM1",0.345713720441091,"NA",0,0,1,1.15821E-4,{"v":3.52619e-16,"d":"3.53E-16"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops",{"v":1.7e-09,"d":"1.70E-09"},"rs35271870;rs1337248",5]
["ENSG00000143674","MLK4",1,233463514,233520894,1,"protein_coding",84451,"MAP3K21",0.000607298684335364,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":7.6e-13,"d":"7.60E-13"},"rs633269:rs822928",6]
["ENSG00000059588","TARBP1",1,234527059,234614849,-1,"protein_coding",6894,"TARBP1",{"v":5.69518410914162e-16,"d":"5.70E-16"},0.440309518,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.6e-13,"d":"7.60E-13"},"rs633269:rs822928",6]
["ENSG00000168264","IRF2BP2",1,234740015,234745271,-1,"protein_coding",359948,"IRF2BP2",0.470291318540817,-0.545562654,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Adrenal:Aorta:Bladder:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Lung:Pancreas:Psoas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.6e-13,"d":"7.60E-13"},"rs633269:rs822928",6]
["ENSG00000173726","TOMM20",1,235272651,235292251,-1,"protein_coding",9804,"TOMM20",0.577780758415904,-1.79497007,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":7.6e-13,"d":"7.60E-13"},"rs633269:rs822928",6]
["ENSG00000188739","RBM34",1,235294498,235324772,-1,"protein_coding",23029,"RBM34",{"v":7.9464873955861e-09,"d":"7.95E-09"},-0.245373815,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":7.6e-13,"d":"7.60E-13"},"rs633269:rs822928",6]
["ENSG00000163029","SMC6",2,17845079,17981509,-1,"protein_coding",79677,"SMC6",0.455419790303775,-0.256064404,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":6.3e-17,"d":"6.30E-17"},"rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854",7]
["ENSG00000151379","MSGN1",2,17997763,17998368,1,"protein_coding",343930,"MSGN1",0.191097329641165,0.290090795,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":6.3e-17,"d":"6.30E-17"},"rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854",7]
["ENSG00000240857","RDH14",2,18735989,18741946,-1,"protein_coding",57665,"RDH14",0.232943493348579,-0.65948759,0,0,0,"NA","NA","NA","NA","Yes","IMR90:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908","07:08:00"]
["ENSG00000183891","TTC32",2,20096404,20101747,-1,"protein_coding",130502,"TTC32",0.0898978964968043,0.090613208,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":9e-20,"d":"9.00E-20"},"rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs1107852:rs2881925:rs907866;rs2881925",7]
["ENSG00000118965","WDR35",2,20110021,20189892,-1,"protein_coding",57539,"WDR35",{"v":2.64838406754913e-16,"d":"2.65E-16"},0.068467282,0,0,5,{"v":2.82344e-05,"d":"2.82E-05"},{"v":1.86848e-12,"d":"1.87E-12"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9e-20,"d":"9.00E-20"},"rs7600854;rs907869;rs907866;rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854:rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs1107852:rs2881925:rs907866;rs2881925",7]
["ENSG00000132031","MATN3",2,20191872,20212455,-1,"protein_coding",4148,"MATN3",{"v":1.61181027463323e-06,"d":"1.61E-06"},-0.325742707,0,0,20,{"v":6.26658e-08,"d":"6.27E-08"},{"v":7.07784e-56,"d":"7.08E-56"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-17,"d":"2.50E-17"},"rs13010903;rs7600854;rs907866;rs907869;rs1107852;rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs7600854:rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T",7]
["ENSG00000068697","LAPTM4A",2,20232411,20251789,-1,"protein_coding",9741,"LAPTM4A",0.503802410255576,0.09428312,0,0,1,{"v":1.47154e-06,"d":"1.47E-06"},{"v":1.35355e-33,"d":"1.35E-33"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":1.9E-28,"d":"1.90E-28"},"rs11687133;rs4075673:rs62120852:rs6544366;rs4296389:rs533617","07:08:00"]
["ENSG00000115884","SDC1",2,20400558,20425194,-1,"protein_coding",6382,"SDC1",0.290469547271798,-1.717413757,21,22.1,21,{"v":4.72337e-14,"d":"4.72E-14"},{"v":7.25196e-13,"d":"7.25E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":9e-20,"d":"9.00E-20"},"rs2881925;rs907866;rs11096646;2:20401858_TA_T;rs13010903;rs11687133;rs7600854;rs907869;rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs7600854:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs1107852:rs2881925:rs907866;rs2881925:rs11096646:rs11096646",7]
["ENSG00000055917","PUM2",2,20448452,20551995,-1,"protein_coding",23369,"PUM2",0.999922863782349,-1.032631297,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854:rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs1107852:rs2881925:rs907866;rs2881925:rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908","07:08:00"]
["ENSG00000143878","RHOB",2,20646835,20649200,1,"protein_coding",388,"RHOB",0.245030976539202,-0.338452643,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":6.4e-52,"d":"6.40E-52"},"rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908",8]
["ENSG00000118960","HS1BP3",2,20760208,20850849,-1,"protein_coding",64342,"HS1BP3",0.000353324886507251,2.114325929,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs62120852:rs36134738:rs11685356;rs13414987:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs13414987:rs139919599:rs6544366;rs4296389:rs4075673:rs4296389:rs4426495:rs11680233:rs12691202:rs585967:2:21266774_GGCAGCGCCA_G;rs61539677:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:rs60403635:rs668948;rs585967;rs7419374:2:21277213_GCT_G:rs668948:rs111826230:rs34468875;2:21266774_GGCAGCGCCA_G;rs61539677:rs61539677:rs668948;rs34601365;rs432483:rs375330151:rs71435594:rs5829778:rs668948;rs7419374:rs668948;rs432483:rs34468875;rs61539677:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548",8]
["ENSG00000143869","GDF7",2,20866424,20873418,1,"protein_coding",151449,"GDF7",0.778067351749562,0.171953881,0,0,5,{"v":6.68769e-05,"d":"6.69E-05"},{"v":4.73948e-07,"d":"4.74E-07"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs949790;rs7566040;rs62120852:rs36134738:rs11685356;rs13414987:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs13414987:rs139919599:rs6544366;rs4296389:rs4075673:rs4296389:rs4426495:rs11680233:rs12691202:rs585967:2:21266774_GGCAGCGCCA_G;rs61539677:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:rs60403635:rs668948;rs585967;rs7419374:2:21277213_GCT_G:rs668948:rs111826230:rs34468875;2:21266774_GGCAGCGCCA_G;rs61539677:rs61539677:rs668948;rs34601365;rs432483:rs375330151:rs71435594:rs5829778:rs668948;rs7419374:rs668948;rs432483:rs34468875;rs61539677:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548",8]
["ENSG00000118961","C2orf43",2,20883788,21022882,-1,"protein_coding",60526,"C2orf43",0.00064748477489379,-0.605069014,0,0,61,{"v":6.33584e-07,"d":"6.34E-07"},{"v":1.70489e-23,"d":"1.70E-23"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs693;2:21266774_GGCAGCGCCA_G;rs61539677;rs34468875;rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs13414987:rs139919599:rs6544366;rs4296389:rs11685356;rs13414987:rs4075673:rs4296389:rs4426495:2:21266774_GGCAGCGCCA_G;rs61539677:rs668948;rs585967;rs7419374:rs668948:rs60403635:rs111826230:rs34468875;rs61539677:rs61539677:rs668948;rs34601365;rs432483:rs375330151:rs71435594:rs36134738:rs11680233:rs12691202:rs585967:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:2:21277213_GCT_G:rs5829778:rs668948;rs7419374:rs668948;rs432483:rs34468875;rs61539677:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548",8]
["ENSG00000084674","APOB",2,21224301,21266945,-1,"protein_coding",338,"APOB",{"v":5.49085163436995e-16,"d":"5.49E-16"},-0.34689194,57,24.9,443,{"v":4.92464e-29,"d":"4.92E-29"},{"v":1.88901e-24,"d":"1.89E-24"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs12713956;rs62122481;rs693;rs6544366;rs11680233;rs533617;rs74410908;rs12691202;rs139919599;rs585967;2:21266774_GGCAGCGCCA_G;rs61539677;rs668948;rs17398765;rs60403635;rs7419374;rs62120852;rs4296389;rs4075673;rs34468875;rs949790;rs4635554;rs7566040;rs11685356;rs13414987;rs34601365;rs432483;rs10177017;rs312033;rs4426495;rs36134738;rs71435594;rs5829778;rs1848922;rs7571647;rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:2:21266774_GGCAGCGCCA_G;rs61539677:rs668948;rs7419374:rs668948:rs60403635:rs111826230:rs34468875;rs61539677:rs61539677:rs668948;rs432483:rs375330151:rs71435594:rs5829778:rs668948;rs7419374:rs17398765:rs668948;rs432483:rs34468875;rs61539677:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548",8]
["ENSG00000218819","TDRD15",2,21346789,21366144,1,"protein_coding",100129278,"TDRD15","NA","NA",32,10.66,43,{"v":9.33199e-09,"d":"9.33E-09"},{"v":4.5811e-10,"d":"4.58E-10"},"GTEx/v8/Liver","-","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-52,"d":"6.40E-52"},"rs17398765;rs61539677;rs668948;rs7419374;rs34601365;rs432483;rs34468875;2:21266774_GGCAGCGCCA_G;rs375330151;rs5829778;rs61539677:rs668948;rs585967;rs7419374:rs668948:rs60403635:rs111826230:rs34468875;rs61539677:rs61539677:rs668948;rs432483:rs375330151:rs71435594:rs668948;rs7419374:rs34601365:rs17398765:rs5829778:rs34468875:rs368220458:rs949790:rs4635554:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548:rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs11680233:rs12691202:rs139919599:rs585967:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:2:21277213_GCT_G",8]
["ENSG00000119771","KLHL29",2,23608088,23931481,1,"protein_coding",114818,"KLHL29","NA",-0.399831988,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":6.4e-52,"d":"6.40E-52"},"rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs11680233:rs12691202:rs139919599:rs585967:2:21266774_GGCAGCGCCA_G;rs61539677:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:rs60403635:rs668948;rs585967;rs7419374:2:21277213_GCT_G:rs668948;rs7419374:rs668948;rs34601365;rs432483:rs34468875;2:21266774_GGCAGCGCCA_G;rs61539677:rs34601365:rs5829778:rs111826230:rs34468875:rs368220458:rs949790:rs4635554:rs375330151:rs668948:rs61539677:rs71435594:rs432483:rs432483;rs10177017:rs7419374:rs35239705:rs432483;rs1848922;rs10177017;rs7571647:rs7566040:rs78620068;rs7571647:rs949790;rs7566040:rs34478966:rs10177017:rs312033:rs432483;rs312033:rs1848922:rs10177017;rs7571647:rs7571647:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548",8]
["ENSG00000224361","AC011239.1",2,23729913,23747214,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.4e-52,"d":"6.40E-52"},"rs62120852:rs6544366:rs11685356:rs12713956:rs62122481:rs693:rs6544366;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs219548;rs59014890:rs59014890:rs78620068:rs4665698:rs219548",8]
["ENSG00000143970","ASXL2",2,25956622,26101385,-1,"protein_coding",55252,"ASXL2",0.992738818422806,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1e-09,"d":"1.00E-09"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000268412","AC013449.1",2,26251074,26251481,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1e-09,"d":"1.00E-09"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000084733","RAB10",2,26256976,26360323,1,"protein_coding",10890,"RAB10",0.944404791408518,-0.583904709,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1e-09,"d":"1.00E-09"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000173567","GPR113",2,26531041,26569685,-1,"protein_coding",165082,"GPR113",{"v":1.48528745876047E-10,"d":"1.49E-10"},0.291622367,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1e-09,"d":"1.00E-09"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000157856","DRC1",2,26624784,26679579,1,"protein_coding",92749,"DRC1",{"v":1.30453003302834e-10,"d":"1.30E-10"},0.353225525,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.5e-15,"d":"3.50E-15"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000213699","SLC35F6",2,26987152,27004099,1,"protein_coding",54978,"SLC35F6",0.0161307579092324,-0.353050684,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.5e-15,"d":"3.50E-15"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000115163","CENPA",2,26987157,27023935,1,"protein_coding",1058,"CENPA",0.139975206060218,-0.80838147,0,0,6,{"v":2.63678e-05,"d":"2.64E-05"},{"v":8.50209e-21,"d":"8.50E-21"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":3.5e-15,"d":"3.50E-15"},"rs780090;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000084764","MAPRE3",2,27193480,27250064,1,"protein_coding",22924,"MAPRE3",0.799864407370243,-0.767319281,0,0,4,0.000153562,{"v":6.08981e-07,"d":"6.09E-07"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Fetal_Cortex:Spleen:GM12878:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":6.9e-35,"d":"6.90E-35"},"rs145508558;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs780090:2:27498734_ACCCCCG_A:rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326",9]
["ENSG00000119777","TMEM214",2,27255778,27264563,1,"protein_coding",54867,"TMEM214",0.00116735534958103,-0.517227915,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs780090:2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000084693","AGBL5",2,27265232,27293490,1,"protein_coding",60509,"AGBL5",0.0206948513459665,-0.378650928,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575:rs780090:2:27498734_ACCCCCG_A:rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326",9]
["ENSG00000228474","OST4",2,27293340,27294641,-1,"protein_coding",100128731,"OST4","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs780090:2:27498734_ACCCCCG_A",9]
["ENSG00000138080","EMILIN1",2,27301435,27309271,1,"protein_coding",11117,"EMILIN1",0.00521656081419512,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:2:27498734_ACCCCCG_A:rs780090",9]
["ENSG00000138030","KHK",2,27309615,27323640,1,"protein_coding",3795,"KHK",{"v":5.36079485314004e-05,"d":"5.36E-05"},"NA",0,0,89,{"v":1.27581e-05,"d":"1.28E-05"},{"v":2.2178e-62,"d":"2.22E-62"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575;rs3817588;rs145508558;rs13013484;rs2384575:rs780090:2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978",9]
["ENSG00000138028","CGREF1",2,27321757,27341995,-1,"protein_coding",10669,"CGREF1",{"v":5.50290788195318E-8,"d":"5.50E-08"},0.491986309,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs780090:rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs3817588:2:27498734_ACCCCCG_A",9]
["ENSG00000143994","ABHD1",2,27346682,27353680,1,"protein_coding",84696,"ABHD1",{"v":1.06027288753589e-21,"d":"1.06E-21"},-0.251069432,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs780090:rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs3817588:2:27498734_ACCCCCG_A",9]
["ENSG00000138073","PREB",2,27353624,27357543,-1,"protein_coding",10113,"PREB",0.0018983627682706,-0.154458724,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs80051818:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs2384575:rs780090:rs4665978:2:27498734_ACCCCCG_A",9]
["ENSG00000186143","C2orf53",2,27359723,27362278,-1,"protein_coding",339779,"C2orf53",{"v":1.54927478958821e-09,"d":"1.55E-09"},0.62491408,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1e-09,"d":"1.00E-09"},"rs2384575:rs780090:rs4665978;2:27498734_ACCCCCG_A:2:27498734_ACCCCCG_A",9]
["ENSG00000163792","TCF23",2,27371872,27376378,1,"protein_coding",150921,"TCF23",0.000503312310069814,-0.683069484,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1e-09,"d":"1.00E-09"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs780090:2:27498734_ACCCCCG_A",9]
["ENSG00000138074","SLC5A6",2,27422455,27435826,-1,"protein_coding",8884,"SLC5A6",0.571968337581082,-0.400099261,35,22.3,252,{"v":4.48883e-22,"d":"4.49E-22"},{"v":1.13875E-17,"d":"1.14E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575;rs780090;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27739880_CT_C;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs780090:2:27498734_ACCCCCG_A",9]
["ENSG00000138085","ATRAID",2,27434895,27440046,1,"protein_coding",51374,"ATRAID",0.00791394898030435,"NA",22,15.27,243,{"v":2.34859e-32,"d":"2.35E-32"},{"v":5.3045e-26,"d":"5.30E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":1.3e-37,"d":"1.30E-37"},"rs2384575;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;rs3817588;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs780090:2:27498734_ACCCCCG_A",9]
["ENSG00000084774","CAD",2,27440258,27466811,1,"protein_coding",790,"CAD",0.999999701880854,-0.710759294,45,15.27,238,{"v":1.82619e-25,"d":"1.83E-25"},{"v":9.08683e-20,"d":"9.09E-20"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27498734_ACCCCCG_A:rs80051818:rs2384575:rs4665978;2:27694905_CA_C:rs1260326:rs780090:2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000115194","SLC30A3",2,27476552,27498685,-1,"protein_coding",7781,"SLC30A3",0.64608387237045,-0.660463482,31,12.98,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575;rs780090;2:27498734_ACCCCCG_A;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs780090",9]
["ENSG00000163793","DNAJC5G",2,27498289,27504367,1,"protein_coding",285126,"DNAJC5G",3.97478941010456E-3,-0.706717729,10,5.156,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575;2:27498734_ACCCCCG_A;rs780090;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs780090",9]
["ENSG00000138100","TRIM54",2,27505260,27530307,1,"protein_coding",57159,"TRIM54",{"v":8.24707898322991E-7,"d":"8.25E-07"},-1.053267254,15,8.663,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"2:27498734_ACCCCCG_A;rs780090;rs2384575;rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978:rs4665978;2:27694905_CA_C:rs1260326:rs780090",9]
["ENSG00000163794","UCN",2,27530268,27531313,-1,"protein_coding",7349,"UCN",0.517240162953561,-0.107138113,8,6.564,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.8e-08,"d":"2.80E-08"},"rs780090;rs2384575",9]
["ENSG00000115204","MPV17",2,27532360,27548547,-1,"protein_coding",4358,"MPV17",{"v":1.10286841801097E-8,"d":"1.10E-08"},-0.205368529,12,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":6.9e-35,"d":"6.90E-35"},"rs780090;rs2384575;rs4665978;2:27498734_ACCCCCG_A;rs2384575:rs780090:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs3817588:rs67798437:rs74175068:rs145508558:2:27498734_ACCCCCG_A",9]
["ENSG00000115207","GTF3C2",2,27548716,27579868,-1,"protein_coding",2976,"GTF3C2",0.999786435918561,-0.837016421,34,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs2384575;rs4665978;2:27498734_ACCCCCG_A;rs80051818;rs2384575:rs80051818:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27694905_CA_C:rs1260326:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs4665978:rs3817588:rs67798437:rs74175068:rs145508558:rs780090:2:27498734_ACCCCCG_A:rs1728918:2:27694905_CA_C:rs2178198:2:27766414_CA_C",9]
["ENSG00000115211","EIF2B4",2,27587219,27593353,-1,"protein_coding",8890,"EIF2B4",0.832609528731968,-0.214235303,25,18.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs4665978;2:27498734_ACCCCCG_A;rs80051818;2:27694905_CA_C;rs1260326;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs4665978:rs2384575:rs3817588:rs67798437:rs74175068:rs145508558:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:27498734_ACCCCCG_A:rs1728918:2:27694905_CA_C:rs2178198:2:27766414_CA_C",9]
["ENSG00000115234","SNX17",2,27593389,27599995,1,"protein_coding",9784,"SNX17",0.686180301198043,-0.681943317,24,18.47,196,{"v":1.17643e-13,"d":"1.18E-13"},{"v":2.00912e-09,"d":"2.01E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;rs80051818;2:27694905_CA_C;rs1260326;rs2384575;2:27739880_CT_C;rs74175068;2:28003616_TA_T;rs67798437;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs4665978:rs2384575:rs3817588:rs67798437:rs74175068:rs145508558:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:27498734_ACCCCCG_A:rs1728918:2:27694905_CA_C:rs2178198:2:27766414_CA_C",9]
["ENSG00000163795","ZNF513",2,27600098,27603657,-1,"protein_coding",130557,"ZNF513",0.940738428263313,"NA",18,18.47,67,{"v":3.61445e-05,"d":"3.61E-05"},0.0342333,"GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.9e-35,"d":"6.90E-35"},"rs80051818;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;rs3817588;rs145508558;rs13013484;2:27498734_ACCCCCG_A:rs1728918:rs4665978;2:27694905_CA_C:rs4665978:rs2384575:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs780090:2:27694905_CA_C:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs2178198",9]
["ENSG00000115241","PPM1G",2,27604061,27632554,-1,"protein_coding",5496,"PPM1G",0.996010385533881,-0.482626092,49,12.85,258,{"v":1.94157e-13,"d":"1.94E-13"},{"v":1.67809e-09,"d":"1.68E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;rs1728918;rs2384575;rs80051818;2:27739880_CT_C;rs67798437;rs2178198;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27694905_CA_C:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs780090:2:27694905_CA_C:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs2178198",9]
["ENSG00000115216","NRBP1",2,27650657,27665126,1,"protein_coding",29959,"NRBP1",0.999548511025196,-1.389706011,43,14.1,324,{"v":1.48664E-19,"d":"1.49E-19"},{"v":1.00894E-14,"d":"1.01E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs3817588;rs2384575;rs780090;rs80051818;rs1260326;rs1728918;2:27739880_CT_C;rs67798437;rs74175068;2:28003616_TA_T;rs80051818:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27694905_CA_C:rs1260326:rs4665978:rs780090:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs145508558:rs67798437:rs74175068:rs2384575:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:27694905_CA_C:2:27766414_CA_C:rs2178198",9]
["ENSG00000157992","KRTCAP3",2,27665233,27669348,1,"protein_coding",200634,"KRTCAP3",0.0445235342133754,"NA",25,10.57,178,{"v":6.96594E-10,"d":"6.97E-10"},{"v":4.42568e-06,"d":"4.43E-06"},"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs3817588;rs2384575;rs80051818;rs1260326;2:27739880_CT_C;rs67798437;2:27498734_ACCCCCG_A:rs4665978:rs1728918:rs74175068:rs145508558:rs67798437:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:2:27694905_CA_C:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:rs2178198",9]
["ENSG00000138002","IFT172",2,27667238,27712656,-1,"protein_coding",26160,"IFT172",{"v":2.29011817971014E-18,"d":"2.29E-18"},-0.505254909,70,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs3817588;rs780090;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67798437:rs74175068:rs145508558:rs2384575:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs80051818:rs1260326:rs1728918:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:rs2178198",9]
["ENSG00000115226","FNDC4",2,27714750,27718112,-1,"protein_coding",64838,"FNDC4",0.759219015798597,"NA",23,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs780090;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67798437:rs74175068:rs145508558:rs2384575:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs80051818:rs1260326:rs1728918:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:rs2178198",9]
["ENSG00000084734","GCKR",2,27719709,27746554,1,"protein_coding",2646,"GCKR",{"v":3.58392509874806e-16,"d":"3.58E-16"},-0.155697744,67,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs780090;rs1260326;rs3817588;2:27739880_CT_C;rs80051818;rs74175068;rs145508558;rs67798437;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67798437:rs74175068:rs145508558:rs2178198:rs2384575:rs80051818:rs1260326:rs3817588:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs1728918:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C",9]
["ENSG00000233438","AC109829.1",2,27760253,27790011,1,"protein_coding","NA","NA","NA","NA",68,10.48,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs1260326;2:27739880_CT_C;rs3817588;rs4665978;rs74175068;rs145508558;rs67798437;rs13013484;2:27766414_CA_C;rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs3817588:rs780090:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs145508558;rs13013484:rs74175068;2:28003616_TA_T",9]
["ENSG00000221843","C2orf16",2,27799389,27805588,1,"protein_coding",84226,"C2orf16",{"v":3.91661992667067e-17,"d":"3.92E-17"},-0.329746802,23,17.52,3,{"v":4.21915e-06,"d":"4.22E-06"},0.0141403,"GTEx/v8/Liver","-","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs145508558;rs74175068;rs67798437;rs3817588;rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs3817588:rs780090:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs145508558;rs13013484:rs74175068;2:28003616_TA_T",9]
["ENSG00000243943","ZNF512",2,27805897,27858041,1,"protein_coding",84450,"ZNF512",0.949146986047491,-1.279253328,77,18.65,6,{"v":8.67923e-05,"d":"8.68E-05"},0.0461625,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs67798437;rs145508558;rs74175068;rs780090;rs13013484;2:28003616_TA_T;rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs780090:rs2384575:rs3817588:rs74175068:rs145508558:rs67798437:rs80051818:rs1260326:2:27694905_CA_C:rs1728918:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C",9]
["ENSG00000176714","CCDC121",2,27848506,27851879,-1,"protein_coding",79635,"CCDC121",{"v":9.72713578876563e-05,"d":"9.73E-05"},-0.266319334,20,18.65,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs145508558;rs67798437;rs74175068;rs780090;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs3817588:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs780090:2:27694905_CA_C:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs145508558;rs13013484:2:27766414_CA_C:rs74175068;2:28003616_TA_T:rs2178198",9]
["ENSG00000198522","GPN1",2,27851114,27874375,1,"protein_coding",11321,"GPN1",0.0049035919998219,-0.238154635,21,14.13,216,{"v":7.93394e-08,"d":"7.93E-08"},0.000297808,"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs67798437;rs145508558;rs780090;rs74175068;rs13013484;2:28003616_TA_T;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27739880_CT_C;2:27694905_CA_C:rs3817588:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs780090:2:27694905_CA_C:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs145508558;rs13013484:2:27766414_CA_C:rs74175068;2:28003616_TA_T:rs2178198",9]
["ENSG00000119760","SUPT7L",2,27873679,27886676,-1,"protein_coding",9913,"SUPT7L",0.833193338587633,-0.966218532,11,10.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":1.3e-37,"d":"1.30E-37"},"rs145508558;rs13013484;rs74175068;2:28003616_TA_T;rs2178198;rs780090:rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs80051818:rs1260326:rs1728918:rs3817588:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs145508558;rs13013484:rs74175068",9]
["ENSG00000163798","SLC4A1AP",2,27886338,27917840,1,"protein_coding",22950,"SLC4A1AP",{"v":7.73999085415032e-07,"d":"7.74E-07"},-0.546764453,8,15.03,129,{"v":4.00834e-08,"d":"4.01E-08"},{"v":8.71618E-6,"d":"8.72E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":1.3e-37,"d":"1.30E-37"},"rs145508558;rs13013484;rs74175068;2:28003616_TA_T;rs2178198;rs67798437;rs4665978;rs780090:rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs80051818:rs1260326:rs1728918:rs3817588:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs145508558;rs13013484:rs74175068",9]
["ENSG00000205334","AC074091.13",2,27928653,27938599,-1,"protein_coding",100129995,"LINC01460","NA","NA",10,18.44,40,{"v":1.69114e-05,"d":"1.69E-05"},0.0188373,"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-13,"d":"5.60E-13"},"rs74175068;2:28003616_TA_T;rs145508558;rs13013484;rs13013484:rs145508558;rs13013484:2:28003616_TA_T:rs2178198",9]
["ENSG00000243147","MRPL33",2,27994584,28210954,1,"protein_coding",9553,"MRPL33",0.749164756585824,-0.22012956,115,19.66,177,{"v":3.59543e-09,"d":"3.60E-09"},{"v":2.0615e-05,"d":"2.06E-05"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-13,"d":"5.60E-13"},"rs13013484;2:28003616_TA_T;rs145508558;rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs13013484:2:28003616_TA_T:rs2178198",9]
["ENSG00000268656","AC110084.1",2,27998851,28009186,-1,"protein_coding","NA","NA","NA","NA",19,19.66,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-35,"d":"1.70E-35"},"rs145508558;rs13013484;2:28003616_TA_T;rs4665978;2:27498734_ACCCCCG_A:rs1260326;2:27739880_CT_C:rs3817588:rs4665978:rs80051818:rs13013484:rs2178198:rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:2:28003616_TA_T",9]
["ENSG00000171174","RBKS",2,28004231,28113965,-1,"protein_coding",64080,"RBKS",{"v":1.93197572918752E-5,"d":"1.93E-05"},-0.689745423,82,19.66,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-13,"d":"5.60E-13"},"rs13013484;rs145508558;2:28003616_TA_T;rs13013484:2:28003616_TA_T:rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs2178198",9]
["ENSG00000158019","BRE",2,28112808,28561768,1,"protein_coding",9577,"BRE",0.279976282823241,"NA",51,16.05,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-13,"d":"5.60E-13"},"rs13013484;2:28003616_TA_T;rs2178198;rs13013484:2:28003616_TA_T:rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs2178198",9]
["ENSG00000075426","FOSL2",2,28615315,28640179,1,"protein_coding",2355,"FOSL2",0.925334261981773,-2.20415963,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Aorta:Bladder:Left_Ventricle:Liver:Lung:Pancreas:Psoas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.9e-35,"d":"6.90E-35"},"rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs13013484:2:28003616_TA_T:rs2178198:rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs780090:2:27694905_CA_C:rs74175068:rs67798437:rs3817588",9]
["ENSG00000163803","PLB1",2,28680012,28866654,1,"protein_coding",151056,"PLB1",{"v":1.9931529274349E-56,"d":"1.99E-56"},0.411383907,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3e-37,"d":"1.30E-37"},"rs67798437:rs74175068:rs145508558:rs74175068;2:28003616_TA_T:rs13013484:2:28003616_TA_T:rs145508558;rs13013484:rs2178198:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs780090:2:27694905_CA_C:2:27766414_CA_C:rs1260326:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs80051818",9]
["ENSG00000213639","PPP1CB",2,28974506,29025806,1,"protein_coding",5500,"PPP1CB",0.997194974203565,0.001839166,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-18,"d":"2.30E-18"},"rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs780090:rs74175068;2:28003616_TA_T:rs13013484:rs145508558;rs13013484:2:28003616_TA_T:2:27694905_CA_C:rs74175068:rs145508558:rs67798437:rs2178198",9]
["ENSG00000163806","SPDYA",2,29005383,29073477,1,"protein_coding",245711,"SPDYA",0.166884223990281,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-18,"d":"2.30E-18"},"rs74175068:rs145508558:rs67798437:rs780090:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs2178198:2:28003616_TA_T:rs13013484",9]
["ENSG00000171103","TRMT61B",2,29072687,29093167,-1,"protein_coding",55006,"TRMT61B",{"v":4.00751770882134e-06,"d":"4.01E-06"},-0.602142186,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-18,"d":"2.30E-18"},"rs2384575:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs74175068;2:28003616_TA_T:rs13013484:rs145508558;rs13013484:rs74175068:rs145508558:rs67798437:rs780090",9]
["ENSG00000163811","WDR43",2,29117509,29171088,1,"protein_coding",23160,"WDR43",0.998942440488972,1.455113129,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-13,"d":"5.60E-13"},"rs13013484:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs145508558",9]
["ENSG00000171094","ALK",2,29415640,30144432,-1,"protein_coding",238,"ALK",0.522362516846561,-0.624899803,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.5e-18,"d":"1.50E-18"},"rs74175068:rs145508558;rs13013484:rs67798437:rs145508558:2:27766414_CA_C",9]
["ENSG00000115944","COX7A2L",2,42560686,42652228,-1,"protein_coding",9167,"COX7A2L",0.00041024940040515,-0.898949558,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000171126","KCNG3",2,42669157,42721237,-1,"protein_coding",170850,"KCNG3",0.0405974403481221,0.146034981,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000057935","MTA3",2,42721709,42984087,1,"protein_coding",57504,"MTA3",0.855163471897877,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000162881","OXER1",2,42989642,42991401,-1,"protein_coding",165140,"OXER1",{"v":4.76881321179725e-07,"d":"4.77E-07"},0.339144756,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000115970","THADA",2,43393800,43823185,-1,"protein_coding",63892,"THADA",{"v":1.24008146143984E-28,"d":"1.24E-28"},-0.379900358,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000152527","PLEKHH2",2,43864412,43995126,1,"protein_coding",130271,"PLEKHH2",{"v":1.78874098604568e-26,"d":"1.79E-26"},0.460070846,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542:rs750542815",10]
["ENSG00000138036","DYNC2LI1",2,44001178,44037149,1,"protein_coding",51626,"DYNC2LI1",{"v":8.37968944079953e-05,"d":"8.38E-05"},1.048101021,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000138075","ABCG5",2,44039611,44066004,-1,"protein_coding",64240,"ABCG5",{"v":1.89797083861304e-15,"d":"1.90E-15"},1.020983846,18,22.8,0,"NA","NA","NA","NA","No","NA",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534;rs4299376",10]
["ENSG00000143921","ABCG8",2,44066103,44105605,1,"protein_coding",64241,"ABCG8",{"v":3.74527259993631e-16,"d":"3.75E-16"},-0.050037409,36,22.8,0,"NA","NA","NA","NA","No","NA",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534;rs4299376;rs7598542;rs750542815",10]
["ENSG00000138095","LRPPRC",2,44113647,44223144,-1,"protein_coding",10128,"LRPPRC",0.000433777803620707,-0.577712281,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542:rs750542815",10]
["ENSG00000138078","PREPL",2,44543420,44589001,-1,"protein_coding",9581,"PREPL",{"v":2.42946176486827e-11,"d":"2.43E-11"},0.105864684,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542:rs750542815",10]
["ENSG00000143919","CAMKMT",2,44589089,44999731,1,"protein_coding",79823,"CAMKMT",{"v":5.14965805552299e-13,"d":"5.15E-13"},0.213319519,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":4.3e-19,"d":"4.30E-19"},"rs11887534:rs4299376:rs7598542:rs750542815",10]
["ENSG00000123607","TTC21B",2,166713985,166810353,-1,"protein_coding",79809,"TTC21B",{"v":3.38768007245796e-22,"d":"3.39E-22"},0.293795588,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586",11]
["ENSG00000169432","SCN9A",2,167051695,167232503,-1,"protein_coding",6335,"SCN9A",{"v":9.30185484244833e-13,"d":"9.30E-13"},1.292595625,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs2389599:rs3770586",11]
["ENSG00000136546","SCN7A",2,167260083,167350757,-1,"protein_coding",6332,"SCN7A",{"v":1.72076245416042E-15,"d":"1.72E-15"},0.83121003,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs3770586:rs2389599",11]
["ENSG00000163092","XIRP2",2,167744997,168116263,1,"protein_coding",129446,"XIRP2",{"v":2.85559362075031e-37,"d":"2.86E-37"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs3770586:rs2389599",11]
["ENSG00000172318","B3GALT1",2,168675182,168730551,1,"protein_coding",8708,"B3GALT1",0.329724363511517,0.177549191,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586",11]
["ENSG00000198648","STK39",2,168810530,169104651,-1,"protein_coding",27347,"STK39",0.999462431417641,-1.274787931,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586",11]
["ENSG00000172292","CERS6",2,169312372,169631644,1,"protein_coding",253782,"CERS6",0.684541332373748,-0.789777756,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs2389599:rs3770586",11]
["ENSG00000163072","NOSTRIN",2,169643049,169722024,1,"protein_coding",115677,"NOSTRIN",{"v":3.5797265988291e-10,"d":"3.58E-10"},-0.276311026,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586:rs2389599",11]
["ENSG00000152253","SPC25",2,169690642,169769881,-1,"protein_coding",57405,"SPC25",0.0594294501038599,-0.350386754,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs3770586:rs2389599",11]
["ENSG00000073734","ABCB11",2,169779448,169887832,-1,"protein_coding",8647,"ABCB11",{"v":2.18849485467569e-10,"d":"2.19E-10"},0.007239117,59,20.8,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586;rs2389599;rs2389599:rs3770586",11]
["ENSG00000073737","DHRS9",2,169921299,169952677,1,"protein_coding",10170,"DHRS9",{"v":2.60804336160151e-07,"d":"2.61E-07"},0.13129231,9,7.782,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs2389599;rs2389599:rs3770586",11]
["ENSG00000081479","LRP2",2,169983619,170219195,-1,"protein_coding",4036,"LRP2",0.99999999999851,-0.83491165,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs2389599:rs3770586",11]
["ENSG00000163093","BBS5",2,170335688,170382432,1,"protein_coding",129880,"BBS5",2.59936459879345E-3,1.335741609,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586:rs2389599",11]
["ENSG00000251569","RP11-724O16.1",2,170335990,170382432,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586:rs2389599",11]
["ENSG00000239474","KLHL41",2,170366212,170382772,1,"protein_coding",10324,"KLHL41",0.0188120404902001,0.17104113,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":5.2e-08,"d":"5.20E-08"},"rs2389599",11]
["ENSG00000154479","CCDC173",2,170501935,170550943,-1,"protein_coding",129881,"CCDC173",{"v":1.08459309632037e-15,"d":"1.08E-15"},0.32133942,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell",{"v":5.2e-08,"d":"5.20E-08"},"rs2389599",11]
["ENSG00000144362","PHOSPHO2",2,170550975,170558218,1,"protein_coding",493911,"PHOSPHO2",0.0155246829335628,0.473325676,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell",{"v":5.2e-08,"d":"5.20E-08"},"rs2389599",11]
["ENSG00000213160","KLHL23",2,170550998,170633499,1,"protein_coding",151230,"KLHL23",0.0206607984994721,4.049362145,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell",{"v":5.2e-08,"d":"5.20E-08"},"rs2389599",11]
["ENSG00000222033","LINC01124",2,171568961,171571077,-1,"protein_coding",440925,"LINC01124","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs3770586:rs2389599",11]
["ENSG00000204335","SP5",2,171571861,171574588,1,"protein_coding",389058,"SP5",0.432721441198873,-0.845891251,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs3770586:rs2389599",11]
["ENSG00000204334","ERICH2",2,171640296,171655481,1,"protein_coding",285141,"ERICH2","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586:rs2389599",11]
["ENSG00000128683","GAD1",2,171669723,171717661,1,"protein_coding",2571,"GAD1",0.82254015260978,0.540076803,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs3770586:rs2389599",11]
["ENSG00000188981","MSANTD1",4,3246096,3273465,1,"protein_coding",345222,"MSANTD1",0.32217221350423,-0.464369361,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":6.3e-15,"d":"6.30E-15"},"rs16844364:rs13108218:rs139750425:rs6818397:rs4690014:rs59950280",12]
["ENSG00000159788","RGS12",4,3294755,3441640,1,"protein_coding",6002,"RGS12",0.00056037428714452,0.073053441,10,6.204,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.3e-15,"d":"6.30E-15"},"rs6818397;rs4690014;rs16844364;rs13108218;rs6818397:rs4690014:rs16844364",12]
["ENSG00000109758","HGFAC",4,3443614,3451211,1,"protein_coding",3083,"HGFAC",{"v":5.20820571636199e-07,"d":"5.21E-07"},-0.328343914,11,6.204,0,"NA","NA","NA","NA","No","NA",{"v":6.3e-15,"d":"6.30E-15"},"rs6818397;rs4690014;rs16844364;rs13108218;rs59950280",12]
["ENSG00000175920","DOK7",4,3465033,3503200,1,"protein_coding",285489,"DOK7",0.00480838202293031,1.760396669,7,4.589,3,{"v":2.169e-07,"d":"2.17E-07"},{"v":2.44181e-29,"d":"2.44E-29"},"GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","+","No","NA",{"v":6.3e-15,"d":"6.30E-15"},"rs139750425;rs13108218;rs4690014",12]
["ENSG00000163956","LRPAP1",4,3508103,3534286,-1,"protein_coding",4043,"LRPAP1",0.00608430596153667,1.96880545,0,0,1,{"v":3.8746e-06,"d":"3.87E-06"},{"v":6.09049e-37,"d":"6.09E-37"},"GTEx/v8/Artery_Tibial","+","No","NA",{"v":1.9E-6,"d":"1.90E-06"},"rs139750425",12]
["ENSG00000163982","OTOP1",4,4190530,4228616,-1,"protein_coding",133060,"OTOP1",{"v":7.31470990584692e-16,"d":"7.31E-16"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.5e-08,"d":"1.50E-08"},"rs139750425",12]
["ENSG00000214944","ARHGEF28",5,72921983,73237818,1,"protein_coding",64283,"ARHGEF28",{"v":1.82695073178584E-10,"d":"1.83E-10"},0.074538928,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.1e-34,"d":"3.10E-34"},"rs7700719:rs144070522:rs72766598:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:rs10942732",13]
["ENSG00000171617","ENC1",5,73923234,73937249,-1,"protein_coding",8507,"ENC1",0.879896897082265,-1.299228704,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.7e-27,"d":"3.70E-27"},"rs34340:rs34340;rs40059;5:74980695_CTT_C:rs4704210;rs253412",13]
["ENSG00000049860","HEXB",5,73935848,74018472,1,"protein_coding",3074,"HEXB",{"v":1.49158509655983e-05,"d":"1.49E-05"},0.069875862,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.7e-27,"d":"3.70E-27"},"rs34340:rs34340;rs40059;5:74980695_CTT_C:rs4704210;rs253412",13]
["ENSG00000164347","GFM2",5,74017029,74063196,-1,"protein_coding",84340,"GFM2",{"v":1.22849095804363E-8,"d":"1.23E-08"},0.221147401,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs7700719:rs144070522:rs72766598:rs7700719;rs6453106:rs4597948;rs72766598:rs6453106:rs73125247;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs10942732;5:74527731_AACAC_A:rs72633976;rs4704171;rs4597948:rs1115091;rs10051260:rs10051260:rs1115091:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs4704171;rs4597948:rs72633976",13]
["ENSG00000164346","NSA2",5,74062817,74072737,1,"protein_coding",10412,"NSA2",0.686235240727363,-0.093199602,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs7700719:rs144070522:rs72766598:rs7700719;rs6453106:rs4597948;rs72766598:rs6453106:rs73125247;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs10942732;5:74527731_AACAC_A:rs72633976;rs4704171;rs4597948:rs1115091;rs10051260:rs10051260:rs1115091:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs4704171;rs4597948:rs72633976",13]
["ENSG00000198780","FAM169A",5,74073399,74162776,-1,"protein_coding",26049,"FAM169A",0.998576224772368,-1.163574677,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs34340;5:74980695_CTT_C:5:74980695_CTT_C:rs253412;rs56912706;rs40059:rs40059:rs253412;rs40059:5:74954025_GA_G:rs253412:rs72766598:rs4597948;rs72766598:rs7706858:rs73125247:rs144070522:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs10942732;5:74527731_AACAC_A:rs72633976;rs4704171;rs4597948:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs40059;5:74980695_CTT_C:rs253412;rs888789:rs253412;rs56912706:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs7700719:rs9293656:rs72633976;5:74733593_TA_T:rs376481168",13]
["ENSG00000176928","GCNT4",5,74323289,74326724,-1,"protein_coding",51301,"GCNT4",0.0212350420721519,1.250076366,30,18.72,407,{"v":5.81264e-30,"d":"5.81E-30"},{"v":1.979e-24,"d":"1.98E-24"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs7706858;rs4597948;rs72766598;rs73125247;rs144070522;rs7700719;rs6453106;rs4555772;rs7714420;rs10942732;rs4704187;rs151000110;rs9293656;rs4704210;rs1820163;rs253412;rs56912706;rs888789;rs258496;rs72633976;rs4704171;rs4597948:rs10942732:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs144070522:rs9293656:rs72633976;5:74733593_TA_T:rs376481168:rs112789140:rs4704262:rs7700719:rs72766598:rs34340;5:74980695_CTT_C:5:74980695_CTT_C:rs253412;rs40059:rs40059:rs253412;rs40059:5:74954025_GA_G:rs253412:5:74973446_TA_T:rs40059;5:74980695_CTT_C:rs253412;rs888789:rs888789:rs7700719;rs6453106:rs4597948;rs72766598:rs6453106:rs73125247;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:rs4704171;rs4597948:rs72633976;rs4704171:rs253412;rs56912706:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs56912706;rs258496:rs4704187:5:74519954_TTA_T",13]
["ENSG00000145700","ANKRD31",5,74364100,74532703,-1,"protein_coding",256006,"ANKRD31","NA","NA",303,16.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle",{"v":6.4e-32,"d":"6.40E-32"},"rs10942732;rs4704187;rs4704171;rs55810502;5:74527731_AACAC_A;rs72633976;rs4597948;rs151000110;5:74519954_TTA_T;rs9293656:rs4704210:rs72633976:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496",13]
["ENSG00000113161","HMGCR",5,74632154,74657929,1,"protein_coding",3156,"HMGCR",0.999836644997739,-0.514442124,42,12.4,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878",{"v":2.6e-34,"d":"2.60E-34"},"rs6895057;rs4704210;rs9293656;rs72633976;5:74733593_TA_T;rs1820163;5:74733593_TA_T:rs9293656:rs72633976:rs4704210;rs1115091:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs888789:rs40059:rs253412;rs40059:rs253412;rs56912706:rs34340;rs40059:rs151000110:rs34340;rs40059:5:74954025_GA_G:rs253412:5:74973446_TA_T",13]
["ENSG00000113163","COL4A3BP",5,74664311,74807963,-1,"protein_coding",10087,"COL4A3BP",0.979474243191344,-1.648108059,107,13.82,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs4704210;rs72633976;rs9293656;5:74733593_TA_T;rs376481168;rs1115091;rs151000110;rs72633976:rs72633976;5:74733593_TA_T:rs9293656:rs4704210:rs4704210;rs1115091:rs4704187;rs10942732:rs4704171:rs10942732:rs72633976;rs4704171:rs4704171;rs4597948:rs34340;5:74980695_CTT_C:5:74980695_CTT_C:rs253412;rs56912706;rs40059:rs40059:rs253412;rs40059:5:74954025_GA_G:rs253412:rs4704210;rs1820163:rs376481168:rs144070522:5:74973446_TA_T:rs40059;5:74980695_CTT_C:rs253412;rs888789:rs888789:rs253412;rs56912706:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs7700719:rs72766598:rs34340:rs34340;rs40059;5:74980695_CTT_C:rs4704210;rs253412:rs542624913",13]
["ENSG00000122008","POLK",5,74807581,74896969,1,"protein_coding",51426,"POLK",{"v":5.99896012883471e-07,"d":"6.00E-07"},-0.474863143,69,14.63,463,{"v":1.94991e-11,"d":"1.95E-11"},{"v":3.07855e-07,"d":"3.08E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-34,"d":"2.60E-34"},"rs72633976;5:74733593_TA_T;rs9293656;rs4704210;rs144070522;rs4555772;rs7706858;rs1820163;rs1115091;rs253412;rs10942732;rs10051260;rs7700719;rs6453106;rs73125247;rs4704187;rs4704171;rs115077527;rs34340;5:74980695_CTT_C;rs72633976:rs72633976;5:74733593_TA_T:rs9293656:rs4704210:rs4704210;rs1115091:rs4704187;rs10942732:rs4704171:rs10942732:rs72633976;rs4704171:rs4704171;rs4597948:rs34340;5:74980695_CTT_C:5:74980695_CTT_C:rs253412;rs56912706;rs40059:rs40059:rs253412;rs40059:5:74954025_GA_G:rs253412:rs4704210;rs1820163:rs376481168:rs144070522:5:74973446_TA_T:rs40059;5:74980695_CTT_C:rs253412;rs888789:rs888789:rs253412;rs56912706:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs7700719:rs72766598:rs34340:rs34340;rs40059;5:74980695_CTT_C:rs4704210;rs253412:rs542624913",13]
["ENSG00000189045","ANKDD1B",5,74907284,74967671,1,"protein_coding",728780,"ANKDD1B","NA",0.593695416,120,45,235,{"v":1.32091E-11,"d":"1.32E-11"},{"v":8.71784e-08,"d":"8.72E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs9293656;rs72633976;5:74733593_TA_T;rs4704210;rs34340;rs40059;5:74980695_CTT_C;rs253412;5:74954025_GA_G;rs542624913;rs56912706;5:74973446_TA_T;rs4704171;rs6895057;rs888789;rs1115091;rs10051260;rs144070522;rs115077527;rs4597948;rs72766598;rs55810502;rs10942732;rs151000110;rs7706858;rs7714420;rs4555772;rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs144070522:rs34340;5:74980695_CTT_C:5:74980695_CTT_C:rs253412;rs40059:rs40059:rs253412;rs40059:5:74954025_GA_G:rs253412:5:74973446_TA_T:rs40059;5:74980695_CTT_C:rs253412;rs888789:rs888789:rs7700719:rs72766598:rs7700719;rs6453106:rs4597948;rs72766598:rs6453106:rs73125247;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:rs4704210;rs1115091:rs34340:rs34340;5:74980695_CTT_C:rs4704210;rs253412:rs542624913:rs253412;rs56912706:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs55810502:rs10942732;5:74527731_AACAC_A:rs72633976;rs4597948:rs1115091;rs10051260:rs10051260:rs1115091:rs4704171;rs4597948:rs72633976",13]
["ENSG00000152359","POC5",5,74969949,75013313,-1,"protein_coding",134359,"POC5",0.00213816175598754,0.193562311,213,45,377,{"v":9.63897e-32,"d":"9.64E-32"},{"v":3.83637e-25,"d":"3.84E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-34,"d":"2.60E-34"},"rs34340;5:74980695_CTT_C;rs253412;rs56912706;rs40059;5:74954025_GA_G;5:74973446_TA_T;rs888789;rs151000110;rs72766598;rs4597948;rs4704171;rs55810502;rs72633976;rs1115091;rs144070522;rs115077527;5:74733593_TA_T;rs4704210;rs112789140;rs258496;rs10051260;rs9293656;rs9293656:rs72633976:rs72633976;5:74733593_TA_T:rs4704210;rs6895057:rs4704210:rs4704210;rs1820163:rs72633976;rs4597948:rs10942732:rs1115091;rs10051260:rs10051260:rs1115091:rs144070522:rs376481168:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:5:74527731_AACAC_A:rs4704171;rs4597948:rs72633976;rs4704171:rs4704210;rs1115091:rs4704262:rs115077527:rs7700719:rs72766598:rs4597948;rs72766598:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs34340;5:74980695_CTT_C:5:74980695_CTT_C:rs253412;rs40059:rs40059:rs253412;rs40059:5:74954025_GA_G:rs253412:5:74973446_TA_T:rs40059;5:74980695_CTT_C:rs253412;rs888789:rs888789:rs144070522;rs115077527:rs7700719;rs6453106:rs6453106:rs73125247;rs7706858:rs4555772;rs7706858:rs4555772:rs151000110:rs258496:rs112789140:rs34340:rs34340;5:74980695_CTT_C:rs4704210;rs253412:rs542624913",13]
["ENSG00000122012","SV2C",5,75378997,75649764,1,"protein_coding",22987,"SV2C",{"v":6.35694393316701e-05,"d":"6.36E-05"},0.609630272,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.1E-18,"d":"2.10E-18"},"5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:rs10942732:rs4704262:rs115077527",13]
["ENSG00000145703","IQGAP2",5,75699074,76003957,1,"protein_coding",10788,"IQGAP2",{"v":4.102950079501e-15,"d":"4.10E-15"},-0.157179038,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs7700719:rs72766598:rs7700719;rs6453106:rs4597948;rs72766598:rs6453106:rs73125247;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:rs10942732:rs72633976;rs4704171;rs4597948:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs144070522:rs4704262:rs115077527:rs144070522;rs115077527:rs4704171;rs4597948:rs72633976;rs4704171:rs9293656:rs72633976;5:74733593_TA_T:rs376481168",13]
["ENSG00000164220","F2RL2",5,75911307,75919259,-1,"protein_coding",2151,"F2RL2",{"v":7.36707093228916e-07,"d":"7.37E-07"},0.52221208,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs7700719:rs144070522:rs72766598:rs4597948;rs72766598:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496",13]
["ENSG00000181104","F2R",5,76011868,76031606,1,"protein_coding",2149,"F2R",0.0412384876728322,-0.795910613,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs7700719:rs144070522:rs72766598:rs4597948;rs72766598:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496",13]
["ENSG00000164251","F2RL1",5,76114758,76131140,1,"protein_coding",2150,"F2RL1",2.02251710092648E-3,-0.779081854,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":3.1e-34,"d":"3.10E-34"},"rs4704187;rs10942732:rs4704171;rs4597948:rs4704171:rs10942732:rs72633976;rs4704171:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168",13]
["ENSG00000145708","CRHBP",5,76248538,76276983,1,"protein_coding",1393,"CRHBP",0.989594470418958,-0.435834082,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1e-34,"d":"3.10E-34"},"rs4704262:rs115077527:rs112789140:rs144070522;rs115077527:rs7700719:rs144070522:rs72766598:rs4597948;rs72766598:rs7706858:rs73125247:rs7714420:rs7714420;rs4555772:rs4597948:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs10942732;5:74527731_AACAC_A:rs72633976;rs4704171;rs4597948:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs9293656:rs72633976;5:74733593_TA_T:rs376481168:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs56912706;rs258496",13]
["ENSG00000164252","AGGF1",5,76325076,76361059,1,"protein_coding",55109,"AGGF1",{"v":6.09962982121775e-05,"d":"6.10E-05"},-0.704749026,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.1e-34,"d":"3.10E-34"},"rs7700719:rs144070522:rs72766598:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:rs10942732:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168",13]
["ENSG00000132846","ZBED3",5,76367897,76383148,-1,"protein_coding",84327,"ZBED3",0.0784364357896077,0.791120221,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.1E-18,"d":"2.10E-18"},"rs7700719:rs144070522:rs72766598:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732;5:74527731_AACAC_A:rs10942732:5:74980695_CTT_C:rs40059;5:74980695_CTT_C:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs40059:rs34340;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140;5:74980695_CTT_C:rs112789140:rs56912706;rs258496",13]
["ENSG00000082516","GEMIN5",5,154266976,154317769,-1,"protein_coding",25929,"GEMIN5",{"v":3.13420201203131E-14,"d":"3.13E-14"},-0.693060045,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.5e-26,"d":"7.50E-26"},"rs4704831:rs6882345:rs4407618:rs752039628:rs6866758:5:156392653_CA_C",14]
["ENSG00000082515","MRPL22",5,154320630,154348971,1,"protein_coding",29093,"MRPL22",{"v":3.44167883429456e-07,"d":"3.44E-07"},0.276799402,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.5e-26,"d":"7.50E-26"},"rs4704819:rs4704831:rs6882345:rs4407618:rs752039628:rs6866758:5:156392653_CA_C:rs70984426",14]
["ENSG00000170624","SGCD",5,155297354,156194799,1,"protein_coding",6444,"SGCD",0.00233910042363156,0.319696283,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.5e-26,"d":"7.50E-26"},"rs4704819:rs4704831:rs6882345:rs4407618:rs752039628:rs6866758:5:156392653_CA_C:rs760614621:rs70984426",14]
["ENSG00000145850","TIMD4",5,156346293,156390266,-1,"protein_coding",91937,"TIMD4",{"v":4.33746964441321e-08,"d":"4.34E-08"},0.360934801,33,10.48,39,{"v":6.1249e-06,"d":"6.12E-06"},0.0123016,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops",{"v":7.5e-26,"d":"7.50E-26"},"rs4704831;rs6882345;rs4407618;rs752039628;rs6866758;5:156392653_CA_C;rs4407618:rs6866758:rs4704831",14]
["ENSG00000113249","HAVCR1",5,156456424,156486130,-1,"protein_coding",26762,"HAVCR1",0.00305433633416917,-0.160669209,85,9.969,132,{"v":2.75285E-18,"d":"2.75E-18"},{"v":5.93632e-22,"d":"5.94E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Coronary","+","Yes","Promoter_anchored_loops",{"v":7.5e-26,"d":"7.50E-26"},"rs4407618;rs4704831;rs6866758;rs70984426;rs6882345;5:156483396_CT_C;rs4704838;rs67960962;rs4704831:rs6866758:rs4407618",14]
["ENSG00000135077","HAVCR2",5,156512843,156569880,-1,"protein_coding",84868,"HAVCR2",0.111384118892431,0.940999528,0,0,23,{"v":5.31832e-05,"d":"5.32E-05"},0.000319789,"GTEx/v8/Artery_Aorta","-","No","NA",{"v":1.4e-13,"d":"1.40E-13"},"rs4407618",14]
["ENSG00000113272","THG1L",5,157158205,157168456,1,"protein_coding",54974,"THG1L",{"v":3.48304059537209e-05,"d":"3.48E-05"},1.451409669,0,0,1,0.000192414,{"v":3.05013e-08,"d":"3.05E-08"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":6.8e-11,"d":"6.80E-11"},"rs4407618",14]
["ENSG00000079689","SCGN",6,25652464,25702011,1,"protein_coding",10590,"SCGN",0.0359460022848758,0.102935794,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.2e-07,"d":"1.20E-07"},"rs1233489",16]
["ENSG00000124568","SLC17A1",6,25783125,25832287,-1,"protein_coding",6568,"SLC17A1",{"v":2.59261497697838e-10,"d":"2.59E-10"},-0.181263012,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.2e-07,"d":"1.20E-07"},"rs1233489",16]
["ENSG00000124564","SLC17A3",6,25833294,25882514,-1,"protein_coding",10786,"SLC17A3",{"v":9.88205561287661e-14,"d":"9.88E-14"},-0.246502705,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1E-8,"d":"1.00E-08"},"rs1233489",16]
["ENSG00000112337","SLC17A2",6,25912982,25930946,-1,"protein_coding",10246,"SLC17A2",0.00466985446742192,-0.129201002,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1233489",16]
["ENSG00000112343","TRIM38",6,25963030,25987384,1,"protein_coding",10475,"TRIM38",{"v":4.75130205096512e-06,"d":"4.75E-06"},-0.220583262,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":8.6e-09,"d":"8.60E-09"},"rs1233489",16]
["ENSG00000124610","HIST1H1A",6,26017260,26018040,-1,"protein_coding",3024,"HIST1H1A",0.00353079926543669,-0.372206788,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000198366","HIST1H3A",6,26020718,26021186,1,"protein_coding",8350,"HIST1H3A",{"v":3.98008178767139e-05,"d":"3.98E-05"},-0.225706842,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000196176","HIST1H4A",6,26021907,26022278,1,"protein_coding",8359,"HIST1H4A",0.00228540295756206,0.434170117,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000124529","HIST1H4B",6,26027124,26027480,-1,"protein_coding",8366,"HIST1H4B",8.54182671998013E-3,0.166119276,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000124693","HIST1H3B",6,26031817,26032288,-1,"protein_coding",8358,"HIST1H3B",0.307282993148648,0.251696243,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000137259","HIST1H2AB",6,26033320,26033796,-1,"protein_coding",8335,"HIST1H2AB",0.00531944331445787,0.228134732,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000010704","HFE",6,26087509,26098571,1,"protein_coding",3077,"HFE",{"v":8.4969700310781e-07,"d":"8.50E-07"},0.210171656,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Neural_Progenitor_Cell",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000197061","HIST1H4C",6,26104104,26104518,1,"protein_coding",8364,"HIST1H4C",{"v":8.85616839210981e-05,"d":"8.86E-05"},0.852191535,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Neural_Progenitor_Cell",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000187475","HIST1H1T",6,26107640,26108364,-1,"protein_coding",3010,"HIST1H1T","NA",-0.068039131,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Neural_Progenitor_Cell",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000197697","HIST1H2BE",6,26183958,26184454,1,"protein_coding",8344,"HIST1H2BE",0.000307871828087192,0.445738376,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Neural_Progenitor_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000188987","HIST1H4D",6,26188938,26189304,-1,"protein_coding",8360,"HIST1H4D",0.00226430020608533,0.870145303,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Neural_Progenitor_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000197409","HIST1H3D",6,26197068,26199521,-1,"protein_coding",8351,"HIST1H3D",0.011195071454157,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Neural_Progenitor_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000196866","HIST1H2AD",6,26199079,26199471,-1,"protein_coding",3013,"HIST1H2AD",{"v":3.99677268819075e-05,"d":"4.00E-05"},0.28775859,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Neural_Progenitor_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000197846","HIST1H2BF",6,26199748,26200942,1,"protein_coding",8343,"HIST1H2BF",0.000300020472922898,0.851062902,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000198518","HIST1H4E",6,26204858,26206266,1,"protein_coding",8367,"HIST1H4E",0.000642250549090646,1.835781936,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000187990","HIST1H2BG",6,26216428,26216872,-1,"protein_coding",8339,"HIST1H2BG",{"v":2.94452400546665E-6,"d":"2.94E-06"},0.025345178,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000168274","HIST1H2AE",6,26217165,26217711,1,"protein_coding",3012,"HIST1H2AE",0.62412365369502,-0.273878285,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000196966","HIST1H3E",6,26225383,26225844,1,"protein_coding",8353,"HIST1H3E",0.000813428842528686,-0.20979509,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000124575","HIST1H1D",6,26234440,26235216,-1,"protein_coding",3007,"HIST1H1D","NA",0.136123163,1,3.14,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000198327","HIST1H4F",6,26240561,26240976,1,"protein_coding",8361,"HIST1H4F",0.181985150966619,1.063119385,1,3.14,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000124578","HIST1H4G",6,26246886,26247259,-1,"protein_coding",8369,"HIST1H4G",0.00262999657981332,-0.050940889,1,3.14,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000256316","HIST1H3F",6,26250370,26250835,-1,"protein_coding",8968,"HIST1H3F",0.042215361750485,-0.181854433,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000197459","HIST1H2BH",6,26251879,26252303,1,"protein_coding",8345,"HIST1H2BH",0.000295729876724394,-0.173874453,1,2.061,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000256018","HIST1H3G",6,26271146,26271612,-1,"protein_coding",8355,"HIST1H3G",{"v":1.71005632806188e-05,"d":"1.71E-05"},0.234420172,5,7.144,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000168242","HIST1H2BI",6,26273144,26273622,1,"protein_coding",8346,"HIST1H2BI",0.138012141980387,-0.249747536,5,7.144,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000158406","HIST1H4H",6,26281283,26285762,-1,"protein_coding",8365,"HIST1H4H",0.00879032933359599,1.05906941,17,12.5,22,{"v":3.04185E-5,"d":"3.04E-05"},0.00670633,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.9e-08,"d":"1.90E-08"},"rs6908402;rs6908402:rs1233489","15:16:00"]
["ENSG00000186470","BTN3A2",6,26365387,26378546,1,"protein_coding",11118,"BTN3A2",0.000124518814289725,2.207914013,0,0,3,{"v":4.99353e-10,"d":"4.99E-10"},{"v":2.09296e-115,"d":"2.09E-115"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000124508","BTN2A2",6,26383324,26395102,1,"protein_coding",10385,"BTN2A2",0.000150288420483044,1.015715449,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000026950","BTN3A1",6,26402465,26415444,1,"protein_coding",11119,"BTN3A1",{"v":8.65113669435817E-7,"d":"8.65E-07"},1.627912919,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":5e-08,"d":"5.00E-08"},"rs6908402",15]
["ENSG00000111801","BTN3A3",6,26440700,26453643,1,"protein_coding",10384,"BTN3A3",{"v":7.19024879190517e-10,"d":"7.19E-10"},1.090110123,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000112763","BTN2A1",6,26458150,26476849,1,"protein_coding",11120,"BTN2A1",{"v":1.07467588553941e-18,"d":"1.07E-18"},0.260570683,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000124557","BTN1A1",6,26501449,26510650,1,"protein_coding",696,"BTN1A1",{"v":1.14088369109076e-09,"d":"1.14E-09"},-0.32970456,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-08,"d":"4.00E-08"},"rs6908402",15]
["ENSG00000182952","HMGN4",6,26538633,26546482,1,"protein_coding",10473,"HMGN4",0.557082341510099,-0.351002587,0,0,1,1.35568E-4,{"v":3.43389e-05,"d":"3.43E-05"},"GTEx/v8/Pancreas","-","Yes","Aorta:Hippocampus:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402;rs6908402:rs1233489","15:16:00"]
["ENSG00000146109","ABT1",6,26597180,26600278,1,"protein_coding",29777,"ABT1",0.0271055673799205,0.104221009,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000181315","ZNF322",6,26636518,26659980,-1,"protein_coding",79692,"ZNF322","NA",-1.140467931,0,0,2,{"v":9.05345e-05,"d":"9.05E-05"},{"v":1.65494E-33,"d":"1.65E-33"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Fetal_Cortex:Left_Ventricle:GM12878:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402;rs6908402:rs1233489","15:16:00"]
["ENSG00000124635","HIST1H2BJ",6,27093676,27100541,-1,"protein_coding",8970,"HIST1H2BJ",0.47884211441258,0.308582046,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000196787","HIST1H2AG",6,27100832,27103070,1,"protein_coding",8969,"HIST1H2AG",0.000610464103704842,-0.741637225,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000197903","HIST1H2BK",6,27106073,27114619,-1,"protein_coding",85236,"HIST1H2BK",0.490754148427297,-0.043052263,0,0,1,0.000600836,0.00164071,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402;rs6908402:rs1233489","15:16:00"]
["ENSG00000198339","HIST1H4I",6,27107076,27108418,1,"protein_coding",8294,"HIST1H4I",0.446296012965993,-0.468005112,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000184825","HIST1H2AH",6,27114861,27115317,1,"protein_coding",85235,"HIST1H2AH",{"v":6.2950794420684e-05,"d":"6.30E-05"},0.194919981,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000112812","PRSS16",6,27215480,27224403,1,"protein_coding",10279,"PRSS16",{"v":2.23791834002529e-06,"d":"2.24E-06"},0.008848123,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489:rs6908402","15:16:00"]
["ENSG00000158553","POM121L2",6,27253682,27279949,-1,"protein_coding",94026,"POM121L2","NA",0.313408259,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489:rs6908402","15:16:00"]
["ENSG00000124613","ZNF391",6,27342394,27371683,1,"protein_coding",346157,"ZNF391",{"v":9.25869403182407e-07,"d":"9.26E-07"},1.231716533,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000096654","ZNF184",6,27418522,27440897,-1,"protein_coding",7738,"ZNF184",0.133748635714874,-0.545662357,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000185130","HIST1H2BL",6,27775257,27775709,-1,"protein_coding",8340,"HIST1H2BL",0.00286755404850941,-0.03011099,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000196747","HIST1H2AI",6,27775899,27776429,1,"protein_coding",8329,"HIST1H2AI",0.581587114173739,-0.058326504,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000203813","HIST1H3H",6,27777842,27778314,1,"protein_coding",8357,"HIST1H3H",0.02493915563981,-0.177817416,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000182611","HIST1H2AJ",6,27782112,27782607,-1,"protein_coding",8331,"HIST1H2AJ",0.19119768143705,0.615053632,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000196374","HIST1H2BM",6,27782822,27783267,1,"protein_coding",8342,"HIST1H2BM",0.00275346435077864,-0.27562,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000197238","HIST1H4J",6,27791884,27792257,1,"protein_coding",8363,"HIST1H4J",0.423753830207411,0.598449973,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000197914","HIST1H4K",6,27798952,27799305,-1,"protein_coding",8362,"HIST1H4K",0.429118935200097,0.387416315,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000184348","HIST1H2AK",6,27805658,27806117,-1,"protein_coding",8330,"HIST1H2AK",0.0684285015781424,-0.04124411,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000233822","HIST1H2BN",6,27806323,27823487,1,"protein_coding",8341,"HIST1H2BN",0.139774615254902,0.145508408,0,0,81,{"v":2.60316E-5,"d":"2.60E-05"},0.00215173,"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-8,"d":"1.00E-08"},"rs1233489;rs6908402:rs1233489","15:16:00"]
["ENSG00000198374","HIST1H2AL",6,27833034,27833606,1,"protein_coding",8332,"HIST1H2AL",0.0624869158210738,-0.360341181,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000184357","HIST1H1B",6,27834570,27835359,-1,"protein_coding",3009,"HIST1H1B",0.509138756022723,-0.08989506,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-08,"d":"2.50E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000182572","HIST1H3I",6,27839623,27840099,-1,"protein_coding",8354,"HIST1H3I",0.360879945054601,-0.232438013,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000198558","HIST1H4L",6,27840926,27841289,-1,"protein_coding",8368,"HIST1H4L",0.191234624133278,0.426890108,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000197153","HIST1H3J",6,27858093,27860884,-1,"protein_coding",8356,"HIST1H3J",0.695883936820569,-0.189708056,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-8,"d":"1.00E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000233224","HIST1H2AM",6,27860477,27860963,-1,"protein_coding",8336,"HIST1H2AM",0.000856482029037302,-0.225135146,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-8,"d":"1.00E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000196331","HIST1H2BO",6,27861203,27861669,1,"protein_coding",8348,"HIST1H2BO",{"v":3.07277582735277E-5,"d":"3.07E-05"},-0.223062534,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1E-8,"d":"1.00E-08"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000168131","OR2B2",6,27878963,27880174,-1,"protein_coding",81697,"OR2B2",{"v":6.86720334316105e-05,"d":"6.87E-05"},-0.212076212,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000124657","OR2B6",6,27925019,27925960,1,"protein_coding",26212,"OR2B6",0.0407309275321611,-0.098173144,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000197279","ZNF165",6,28048753,28057341,1,"protein_coding",7718,"ZNF165",0.000563292029886091,0.227981468,0,0,188,{"v":1.60443E-6,"d":"1.60E-06"},{"v":1.94586E-12,"d":"1.95E-12"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs1233489",16]
["ENSG00000196812","ZSCAN16",6,28092338,28097860,1,"protein_coding",80345,"ZSCAN16",{"v":2.67303498489914e-06,"d":"2.67E-06"},0.184187397,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000198315","ZKSCAN8",6,28109688,28127250,1,"protein_coding",7745,"ZKSCAN8",2.31594506551783E-4,-0.142528224,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000137185","ZSCAN9",6,28192664,28201260,1,"protein_coding",7746,"ZSCAN9",{"v":4.10248860506101e-08,"d":"4.10E-08"},0.461166178,0,0,182,0.000108097,{"v":1.5619e-05,"d":"1.56E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878",{"v":8.6e-09,"d":"8.60E-09"},"rs1233489;rs1233489:rs6908402","15:16:00"]
["ENSG00000187626","ZKSCAN4",6,28212401,28227011,-1,"protein_coding",387032,"ZKSCAN4",{"v":6.74288454800845e-05,"d":"6.74E-05"},0.661631344,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000189134","NKAPL",6,28227098,28228736,1,"protein_coding",222698,"NKAPL",0.000165621301014734,0.051342603,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs6908402:rs1233489","15:16:00"]
["ENSG00000137338","PGBD1",6,28249314,28270326,1,"protein_coding",84547,"PGBD1",{"v":1.46735073363618E-5,"d":"1.47E-05"},-0.0800605,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.6e-08,"d":"4.60E-08"},"rs6908402",15]
["ENSG00000235109","ZSCAN31",6,28292470,28324048,-1,"protein_coding",64288,"ZSCAN31",{"v":3.7712697083703e-09,"d":"3.77E-09"},1.107125092,0,0,123,{"v":2.23396E-7,"d":"2.23E-07"},{"v":4.37287e-25,"d":"4.37E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","-","Yes","Mesendoderm",{"v":8.6e-09,"d":"8.60E-09"},"rs1233489",16]
["ENSG00000189298","ZKSCAN3",6,28317691,28336947,1,"protein_coding",80317,"ZKSCAN3",0.000122608322341288,-0.65244291,0,0,120,{"v":5.36117E-6,"d":"5.36E-06"},{"v":4.57962e-07,"d":"4.58E-07"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","No","NA",{"v":8.6e-09,"d":"8.60E-09"},"rs1233489",16]
["ENSG00000158691","ZSCAN12",6,28346732,28367511,-1,"protein_coding",9753,"ZSCAN12",{"v":1.43991732878074E-5,"d":"1.44E-05"},"NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000187987","ZSCAN23",6,28399707,28411279,-1,"protein_coding",222696,"ZSCAN23",0.00270295085017911,0.070656525,0,0,240,{"v":2.63038e-08,"d":"2.63E-08"},{"v":8.30529e-55,"d":"8.31E-55"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs1233489",16]
["ENSG00000198704","GPX6",6,28471073,28495992,-1,"protein_coding",257202,"GPX6",{"v":3.13757952195529e-05,"d":"3.14E-05"},0.718702709,1,0.984,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000224586","GPX5",6,28493702,28502729,1,"protein_coding",2880,"GPX5",0.00888467745572368,0.354876486,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000232040","SCAND3",6,28539407,28583989,-1,"protein_coding",114821,"SCAND3",{"v":9.70724396864633e-09,"d":"9.71E-09"},-0.785031462,2,10.48,3,0.000192045,0.000305781,"GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs1233489",16]
["ENSG00000204713","TRIM27",6,28870779,28891766,-1,"protein_coding",5987,"TRIM27",0.878751858118275,-0.142067713,15,18.69,4,{"v":9.05276e-05,"d":"9.05E-05"},{"v":9.5578e-15,"d":"9.56E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs1233489",16]
["ENSG00000204709","C6orf100",6,28911654,28912314,1,"protein_coding",729583,"C6orf100","NA","NA",8,3.641,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs1233489",16]
["ENSG00000197935","ZNF311",6,28962562,28973093,-1,"protein_coding",282890,"ZNF311",0.000129446471411909,0.377857886,9,11.6,1,{"v":4.51825e-05,"d":"4.52E-05"},{"v":1.05129e-10,"d":"1.05E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204704","OR2W1",6,29011990,29013017,-1,"protein_coding",26692,"OR2W1",0.0865618905271982,0.531528388,7,6.576,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204703","OR2B3",6,29053985,29055090,-1,"protein_coding",442184,"OR2B3",1.3369321318042E-3,0.458839963,3,9.377,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204702","OR2J1",6,29068386,29069658,1,"protein_coding",442185,"OR2J1",0.0174945019459341,"NA",1,0.549,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204701","OR2J3",6,29079668,29080603,1,"protein_coding",442186,"OR2J3",0.0281435008681581,0.112859372,2,1.351,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204700","OR2J2",6,29141311,29142351,1,"protein_coding",26707,"OR2J2",0.0107267189301636,0.271259236,4,5.147,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":3.6E-9,"d":"3.60E-09"},"rs1233489",16]
["ENSG00000204695","OR14J1",6,29274403,29275519,1,"protein_coding",442191,"OR14J1",{"v":8.02406099709927e-08,"d":"8.02E-08"},1.335471591,4,10.49,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000243729","OR5V1",6,29323007,29399744,-1,"protein_coding",81696,"OR5V1",0.00344261897900665,0.32363506,13,11.39,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000112462","OR12D3",6,29341200,29343068,-1,"protein_coding",81797,"OR12D3",{"v":1.34136303903671e-05,"d":"1.34E-05"},0.883548764,5,11.39,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000168787","OR12D2",6,29364416,29365448,1,"protein_coding",26529,"OR12D2",0.601033125257784,0.457835329,3,6.779,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204694","OR11A1",6,29393281,29424848,-1,"protein_coding",26531,"OR11A1",0.0434844025575059,1.230255274,4,3.951,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000206474","OR10C1",6,29407083,29408731,1,"protein_coding",442194,"OR10C1",0.227592079399406,0.363897038,3,1.81,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204688","OR2H1",6,29424958,29432105,1,"protein_coding",26716,"OR2H1",0.0449040613109769,-0.358288136,4,3.951,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204687","MAS1L",6,29454474,29455738,-1,"protein_coding",116511,"MAS1L",0.000466205666114264,0.689547747,5,8.385,0,"NA","NA","NA","NA","Yes","Aorta:Liver:Pancreas:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000213886","UBD",6,29523292,29527702,-1,"protein_coding",10537,"UBD",0.0798957514124674,0.401530797,5,14.02,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000204681","GABBR1",6,29523406,29601753,-1,"protein_coding",2550,"GABBR1",0.999969901472702,0.238892484,10,14.02,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.8E-9,"d":"1.80E-09"},"rs1233489",16]
["ENSG00000204657","OR2H2",6,29555683,29556745,1,"protein_coding",7932,"OR2H2",0.0899459247726437,0.69683603,4,3.904,268,{"v":1.16286e-09,"d":"1.16E-09"},{"v":1.93261E-11,"d":"1.93E-11"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs1233489",16]
["ENSG00000112514","CUTA",6,33384219,33386094,-1,"protein_coding",51596,"CUTA",{"v":1.14218167340545E-5,"d":"1.14E-05"},-0.619995669,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.6e-09,"d":"2.60E-09"},"rs114863007",17]
["ENSG00000197283","SYNGAP1",6,33387847,33421466,1,"protein_coding",8831,"SYNGAP1",0.999998449747972,-1.109120657,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.6e-09,"d":"2.60E-09"},"rs114863007",17]
["ENSG00000204188","GGNBP1",6,33551515,33556803,1,"protein_coding",449520,"GGNBP1","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.9e-09,"d":"1.90E-09"},"rs114863007",17]
["ENSG00000137288","UQCC2",6,33662070,33679504,-1,"protein_coding",84300,"UQCC2",0.0595477327271092,0.254207876,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.6e-09,"d":"2.60E-09"},"rs114863007",17]
["ENSG00000161896","IP6K3",6,33689444,33714762,-1,"protein_coding",117283,"IP6K3",0.0485338526527661,1.72324211,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-09,"d":"2.60E-09"},"rs114863007",17]
["ENSG00000161904","LEMD2",6,33738979,33756913,-1,"protein_coding",221496,"LEMD2",0.302373361272148,0.392920076,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":7.1e-10,"d":"7.10E-10"},"rs114863007",17]
["ENSG00000096395","MLN",6,33762450,33771788,-1,"protein_coding",4295,"MLN",0.00165857384360036,0.983257947,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-09,"d":"2.60E-09"},"rs114863007",17]
["ENSG00000124493","GRM4",6,33989628,34123399,-1,"protein_coding",2914,"GRM4",0.979350085369263,-0.635218754,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-09,"d":"1.90E-09"},"rs114863007",17]
["ENSG00000186577","C6orf1",6,34214157,34217247,-1,"protein_coding",221491,"C6orf1",0.29871864309512,-0.83430399,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.9e-09,"d":"1.90E-09"},"rs36018387:rs114863007",17]
["ENSG00000272325","NUDT3",6,34247456,34360451,-1,"protein_coding",11165,"NUDT3",0.876816622471426,0.134938478,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.1e-10,"d":"7.10E-10"},"rs114863007:rs36018387:rs36018387;rs114863007",17]
["ENSG00000270800","RPS10-NUDT3",6,34256547,34393825,-1,"protein_coding",100529239,"RPS10-NUDT3","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-09,"d":"2.20E-09"},"rs114863007:rs36018387",17]
["ENSG00000124614","RPS10",6,34385231,34393902,-1,"protein_coding",6204,"RPS10",0.946462997504496,0.20471765,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-09,"d":"2.20E-09"},"rs114863007:rs36018387",17]
["ENSG00000124507","PACSIN1",6,34433916,34503006,1,"protein_coding",29993,"PACSIN1",0.991339222233708,-1.593899928,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.9e-09,"d":"1.90E-09"},"rs114863007:rs36018387",17]
["ENSG00000124664","SPDEF",6,34505579,34524110,-1,"protein_coding",25803,"SPDEF",0.711825442176907,-0.407039982,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-09,"d":"2.20E-09"},"rs114863007:rs36018387",17]
["ENSG00000196821","C6orf106",6,34555065,34664636,-1,"protein_coding",64771,"C6orf106",0.454029671085684,-1.135549043,36,14.02,49,{"v":4.83575e-18,"d":"4.84E-18"},{"v":2.73886e-27,"d":"2.74E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.4e-11,"d":"2.40E-11"},"rs114863007;rs36018387;rs114863007:rs36018387",17]
["ENSG00000124562","SNRPC",6,34725183,34741571,1,"protein_coding",6631,"SNRPC",0.727261777653869,-0.351120295,3,8.418,48,{"v":3.9325e-09,"d":"3.93E-09"},{"v":1.95691e-18,"d":"1.96E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":7.1e-10,"d":"7.10E-10"},"rs114863007;rs36018387;rs114863007:rs36018387",17]
["ENSG00000065060","UHRF1BP1",6,34759857,34850915,1,"protein_coding",54887,"UHRF1BP1",{"v":2.46541297366596e-07,"d":"2.47E-07"},-0.83035352,4,7.357,49,{"v":3.97652e-20,"d":"3.98E-20"},{"v":1.98454e-106,"d":"1.98E-106"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.4e-11,"d":"2.40E-11"},"rs114863007;rs36018387;rs114863007:rs114863007:rs36018387",17]
["ENSG00000064995","TAF11",6,34845555,34855866,-1,"protein_coding",6882,"TAF11",0.875431936618392,-0.232568972,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.1e-10,"d":"7.10E-10"},"rs114863007:rs36018387:rs36018387;rs114863007",17]
["ENSG00000064999","ANKS1A",6,34857042,35059179,1,"protein_coding",23294,"ANKS1A",0.84685967793139,0.260682535,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.1e-10,"d":"7.10E-10"},"rs114863007:rs36018387:rs36018387;rs114863007",17]
["ENSG00000124678","TCP11",6,35085848,35116387,-1,"protein_coding",6954,"TCP11",{"v":4.00945484653237e-05,"d":"4.01E-05"},-0.41353592,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.1e-10,"d":"7.10E-10"},"rs36018387;rs114863007:rs36018387:rs114863007",17]
["ENSG00000146197","SCUBE3",6,35182190,35220856,1,"protein_coding",222663,"SCUBE3",0.9999837065276,-0.692415276,1,13,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.1e-10,"d":"7.10E-10"},"rs36018387;rs114863007:rs36018387",17]
["ENSG00000065029","ZNF76",6,35226686,35263762,1,"protein_coding",7629,"ZNF76",{"v":5.07288621916122e-16,"d":"5.07E-16"},0.397539219,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-09,"d":"2.20E-09"},"rs36018387;rs114863007:rs36018387:rs114863007",17]
["ENSG00000112033","PPARD",6,35310335,35395968,1,"protein_coding",5467,"PPARD",0.966868134632325,0.253948931,1,1.155,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.4e-11,"d":"2.40E-11"},"rs36018387",17]
["ENSG00000112039","FANCE",6,35420138,35434880,1,"protein_coding",2178,"FANCE",0.00313889923167915,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.4e-11,"d":"2.40E-11"},"rs36018387",17]
["ENSG00000096060","FKBP5",6,35541362,35696360,-1,"protein_coding",2289,"FKBP5",0.498849476622916,-0.767039177,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.5e-09,"d":"2.50E-09"},"rs114863007:rs36018387",17]
["ENSG00000137392","CLPS",6,35762759,35765088,-1,"protein_coding",1208,"CLPS",0.0562747598072514,0.768244845,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":5.3e-07,"d":"5.30E-07"},"rs114863007",17]
["ENSG00000156711","MAPK13",6,36095586,36107842,1,"protein_coding",5603,"MAPK13",{"v":5.48349848830244E-7,"d":"5.48E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.5e-09,"d":"2.50E-09"},"rs36018387",17]
["ENSG00000112079","STK38",6,36461669,36515247,-1,"protein_coding",11329,"STK38",0.853295086026932,-0.412586124,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.6e-09,"d":"2.60E-09"},"rs114863007",17]
["ENSG00000130363","RSPH3",6,159393903,159421219,-1,"protein_coding",83861,"RSPH3",0.00139623159251261,-0.228791289,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-21,"d":"1.20E-21"},"rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs143843429:rs117379529",18]
["ENSG00000164694","FNDC1",6,159590429,159693141,1,"protein_coding",84624,"FNDC1",{"v":3.07460719768204e-07,"d":"3.07E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs11481286:rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs9457827:rs2065397:rs3777411:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs688359:rs998075:rs648253:rs4709393:rs386453;rs512077:rs512077:rs2504922:rs117733303:rs4708870:rs9295128:rs386453",18]
["ENSG00000112096","SOD2",6,160090089,160183561,-1,"protein_coding",6648,"SOD2",0.237154646295316,1.737932652,0,0,4,{"v":2.73697e-06,"d":"2.74E-06"},0.00366842,"GTEx/v8/Artery_Tibial","+","Yes","Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8E-36,"d":"4.80E-36"},"6:160560880_CATG_C;rs3777420:rs75474551:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs9457827:rs2065397:rs3777411:rs80254170:rs688359:rs998075:rs648253:rs4709393:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs117733303:rs4708870:rs641990:rs7454234:rs117379529",18]
["ENSG00000146457","WTAP",6,160146617,160177351,1,"protein_coding",9589,"WTAP",0.995576734722068,1.745772008,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-20,"d":"2.10E-20"},"rs3777420:rs7750288:rs10945649:rs75474551:rs6932293;rs11481286:rs11481286:rs688359:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs9355288:rs2504922",18]
["ENSG00000120437","ACAT2",6,160181360,160200144,1,"protein_coding",39,"ACAT2",{"v":1.26453863126978e-05,"d":"1.26E-05"},0.731905322,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8E-36,"d":"4.80E-36"},"rs3777420:rs75474551:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs9457827:rs2065397:rs3777411:rs80254170:rs688359:rs998075:rs648253:rs4709393:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs117733303:rs4708870:rs641990:rs7454234:rs117379529",18]
["ENSG00000120438","TCP1",6,160199530,160210781,-1,"protein_coding",6950,"TCP1",0.989085751892209,0.157899873,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs688359:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453;rs512077:rs512077:rs2504922:rs117733303:rs4708870:rs143843429:rs9295128:rs386453",18]
["ENSG00000112110","MRPL18",6,160210844,160219468,1,"protein_coding",29074,"MRPL18",0.000794102804498299,1.581628342,0,0,1,{"v":9.97293e-05,"d":"9.97E-05"},{"v":3.18015e-33,"d":"3.18E-33"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs641990;rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs688359:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453;rs512077:rs512077:rs2504922:rs117733303:rs4708870:rs143843429:rs9295128:rs386453",18]
["ENSG00000146453","PNLDC1",6,160221298,160241736,1,"protein_coding",154197,"PNLDC1",{"v":2.5447781123909e-08,"d":"2.54E-08"},0.054243557,1,6.927,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs11481286;rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs688359:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453;rs512077:rs512077:rs2504922:rs117733303:rs4708870:rs143843429:rs9295128:rs386453",18]
["ENSG00000130368","MAS1",6,160327974,160329108,1,"protein_coding",4142,"MAS1",0.000870823408355688,-0.186942489,2,13.53,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8E-36,"d":"4.80E-36"},"rs75474551;rs75474551:rs3777420:rs9457827:rs6932293;rs11481286:rs2065397:rs3777411:rs80254170:rs7750288:rs10945649:rs11481286:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs688359:rs998075:rs648253:rs4709393:rs2504922:rs386453;rs512077:rs512077:rs117733303:rs4708870:rs10455872:rs6938647",18]
["ENSG00000197081","IGF2R",6,160390131,160534539,1,"protein_coding",3482,"IGF2R",0.999999196216303,-0.312060143,133,23.4,34,{"v":3.35228E-23,"d":"3.35E-23"},{"v":4.7206200000000004E-18,"d":"4.72E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs3777420;rs75474551;rs7750288;rs10945649;rs6932293;rs11481286;rs688359;rs9457827;rs998075;rs648253;rs4709393;rs3777411;rs2065397;rs80254170;rs12208357;6:160560880_CATG_C;rs3777420:rs7750288:rs10945649:rs75474551:rs6932293;rs11481286:rs641990:rs9355288:rs11481286:rs386453;rs512077:rs512077:rs688359:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs117733303:rs4708870:rs9295128;rs117733303:rs78439586:rs2504922:rs143843429:rs117379529:rs9295128:rs386453:rs10455872:rs6938647",18]
["ENSG00000175003","SLC22A1",6,160542821,160579750,1,"protein_coding",6580,"SLC22A1",{"v":1.23977716739769e-13,"d":"1.24E-13"},-0.158083671,21,23.4,72,{"v":5.41977e-14,"d":"5.42E-14"},{"v":3.85687e-11,"d":"3.86E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs6932293;6:160560880_CATG_C;rs12208357;rs4646272;rs3798167;rs622591;rs13211753;rs9457827;rs11481286;rs998075;rs2065397;rs641990:rs9295128:rs386453:rs386453;rs512077:rs512077:rs9295128;rs117733303:rs78439586:rs9355288:rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs2504922:rs117733303:rs4708870:rs9457827:rs2065397:rs3777411:rs80254170:6:160560880_CATG_C:rs3798167:rs622591:rs13211753:rs16891156:rs688359:rs998075:rs648253:rs4709393:rs3903279:rs10455872:rs6938647:6:161030554_GT_G:rs3798223",18]
["ENSG00000112499","SLC22A2",6,160592093,160698670,-1,"protein_coding",6582,"SLC22A2",{"v":1.4191712191388E-9,"d":"1.42E-09"},0.905296138,23,8.19,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs13211753;rs16891156;rs3903279;rs9295128;rs386453;rs512077;rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs641990:rs386453;rs512077:rs512077:rs9295128;rs117733303:rs78439586:rs9355288:rs9295128:rs386453:rs3798167:rs622591:rs13211753:rs16891156",18]
["ENSG00000146477","SLC22A3",6,160769300,160876014,1,"protein_coding",6581,"SLC22A3",{"v":3.31638540911901E-5,"d":"3.32E-05"},0.310629054,93,12.64,156,{"v":1.04917E-18,"d":"1.05E-18"},{"v":7.34452e-14,"d":"7.34E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Psoas:Right_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.1E-39,"d":"6.10E-39"},"rs9295128;rs386453;rs641990;rs512077;rs117733303;rs78439586;rs9355288;rs2504922;rs3798167;rs75474551:rs3777420:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs688359:rs9457827:rs6932293;rs11481286:rs998075:rs648253:rs4709393:rs3777411:rs13211753:rs16891156:rs3903279:rs9295128:rs386453:rs2504922:rs7750288:rs10945649:rs11481286:rs3798167:rs622591:rs386453;rs512077:rs2065397:rs80254170:rs117733303:rs4708870",18]
["ENSG00000198670","LPA",6,160952515,161087407,-1,"protein_coding",4018,"LPA",{"v":2.4422277924849E-32,"d":"2.44E-32"},0.042144435,12,9.933,75,{"v":7.38964e-09,"d":"7.39E-09"},1.04571E-4,"GTEx/v8/Liver","-","No","NA",{"v":4.8E-36,"d":"4.80E-36"},"rs641990;rs10455872;rs6938647;6:161030554_GT_G;rs3798223;rs56393506;rs9295128;rs117733303;rs9355288;rs2504922",18]
["ENSG00000122194","PLG",6,161123270,161174347,1,"protein_coding",5340,"PLG",0.00243511733948206,0.479258267,61,11.99,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.2e-33,"d":"5.20E-33"},"rs10455872;rs139399782;rs1782629;rs74625856;rs139399782:rs74625856:rs1782629:rs641990:rs9295128;rs117733303:rs78439586:rs9355288:rs10214652:rs143843429:rs7454234:rs117379529",18]
["ENSG00000085511","MAP3K4",6,161412759,161538417,1,"protein_coding",4216,"MAP3K4",0.999991910638856,"NA",6,4.413,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.2e-23,"d":"4.20E-23"},"rs7454234;rs143843429;rs117379529;rs139399782:rs74625856:rs1782629:rs10214652:rs143843429:rs7454234:rs117379529",18]
["ENSG00000026652","AGPAT4",6,161551011,161695093,-1,"protein_coding",56895,"AGPAT4",0.674499951839515,0.748253089,3,2.537,2,{"v":8.65824e-06,"d":"8.66E-06"},0.0238264,"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Hippocampus:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.2e-23,"d":"4.20E-23"},"rs117379529;rs143843429;rs143843429:rs139399782:rs7454234:rs117379529:rs641990:rs9355288:rs74625856:rs1782629:rs10214652:rs10455872",18]
["ENSG00000185345","PARK2",6,161768452,163148803,-1,"protein_coding",5071,"PARK2",0.0218088318211922,0.549835313,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.1E-39,"d":"6.10E-39"},"rs143843429:rs10214652:rs7454234:rs117379529:rs139399782:rs74625856:rs1782629:rs641990:rs9295128:rs386453:rs9295128;rs117733303:rs78439586:rs9355288:6:161030554_GT_G:rs2186129:rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs2504922:rs117733303:rs4708870:rs10455872:rs6938647:rs3798223",18]
["ENSG00000112530","PACRG",6,163148164,163736524,1,"protein_coding",135138,"PACRG",0.000104676937493315,0.454746473,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.1E-39,"d":"6.10E-39"},"rs143843429:rs10214652:rs7454234:rs117379529:rs139399782:rs74625856:rs1782629:rs641990:rs9295128:rs386453:rs9295128;rs117733303:rs78439586:rs9355288:6:161030554_GT_G:rs2186129:rs75474551:rs3777420:rs7750288:rs10945649:rs6932293;rs11481286:rs11481286:rs2504922:rs117733303:rs4708870:rs10455872:rs6938647:rs3798223",18]
["ENSG00000225683","AL078585.1",6,163586446,163612840,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.2e-23,"d":"4.20E-23"},"rs10455872:rs139399782:rs1782629:rs74625856:rs10214652:rs143843429:rs7454234:rs117379529",18]
["ENSG00000112531","QKI",6,163835032,163999628,1,"protein_coding",9444,"QKI",0.963163356453829,-0.183477081,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-33,"d":"4.30E-33"},"rs10455872:6:161030554_GT_G:rs3798223:rs7454234:rs143843429:rs117379529:rs139399782:rs74625856:rs1782629:rs10214652",18]
["ENSG00000196313","POM121",7,72349936,72421979,1,"protein_coding",9883,"POM121","NA",-1.370618997,0,0,59,{"v":8.97114e-08,"d":"8.97E-08"},{"v":1.50688E-66,"d":"1.51E-66"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":3.7e-19,"d":"3.70E-19"},"rs35348663;rs34121855;rs42122;7:73042302_GCTTT_G;rs35348663:7:73042302_GCTTT_G;rs42122:rs34121855:rs42122:rs35489648:7:72840443_CT_C:7:73042302_GCTTT_G",19]
["ENSG00000155428","TRIM74",7,72430016,72439997,-1,"protein_coding",378108,"TRIM74",0.780333820359187,-0.947438302,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.1e-16,"d":"8.10E-16"},"7:73042302_GCTTT_G;rs42122:rs35489648:rs34121855",19]
["ENSG00000130305","NSUN5",7,72716514,72722864,-1,"protein_coding",55695,"NSUN5",{"v":1.45415268581091e-06,"d":"1.45E-06"},-0.276519006,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-18,"d":"1.10E-18"},"7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:rs35348663:7:73042302_GCTTT_G:7:72840443_CT_C:rs42122:rs35489648:rs34121855",19]
["ENSG00000146755","TRIM50",7,72726535,72742085,-1,"protein_coding",135892,"TRIM50",{"v":2.72561665019464E-6,"d":"2.73E-06"},-0.790238603,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.9e-17,"d":"2.90E-17"},"rs42122:rs35489648:7:72840443_CT_C:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G;rs35489648:rs34121855;rs35348663:rs34121855:rs35348663",19]
["ENSG00000077800","FKBP6",7,72742167,72772634,1,"protein_coding",8468,"FKBP6",0.13060063873413,-0.33452228,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.9e-17,"d":"2.90E-17"},"rs42122:rs35489648:7:72840443_CT_C:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G;rs35489648:rs34121855;rs35348663:rs34121855:rs35348663",19]
["ENSG00000188763","FZD9",7,72848109,72850450,1,"protein_coding",8326,"FZD9","NA","NA",7,3.057,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-17,"d":"2.90E-17"},"rs42122;7:72840443_CT_C;7:73042302_GCTTT_G;rs35489648;rs34121855;rs35348663;rs42122:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:rs35348663:rs34121855",19]
["ENSG00000009954","BAZ1B",7,72854728,72936608,-1,"protein_coding",9031,"BAZ1B",0.999999562861573,-1.106984422,36,8.812,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-18,"d":"1.10E-18"},"7:73042302_GCTTT_G;rs35489648;rs42122;rs34121855;rs35348663;rs35348663:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:rs34121855:7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G:7:72840443_CT_C:rs42122:rs35489648",19]
["ENSG00000106635","BCL7B",7,72950686,72972332,-1,"protein_coding",9275,"BCL7B",0.706637383924404,-0.386261382,15,14.54,67,{"v":2.54871e-06,"d":"2.55E-06"},{"v":3.40292E-13,"d":"3.40E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":3.7e-19,"d":"3.70E-19"},"rs35348663;7:73042302_GCTTT_G;rs42122;rs34121855;rs35489648;rs35348663:7:73042302_GCTTT_G",19]
["ENSG00000106638","TBL2",7,72983262,72993121,-1,"protein_coding",26608,"TBL2",0.00437650656905421,8.921304858,31,10.3,51,{"v":1.29213e-05,"d":"1.29E-05"},{"v":4.93874e-46,"d":"4.94E-46"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","No","NA",{"v":5e-18,"d":"5.00E-18"},"rs34121855;rs35348663;7:73042302_GCTTT_G;rs42122;rs35489648",19]
["ENSG00000009950","MLXIPL",7,73007524,73038873,-1,"protein_coding",51085,"MLXIPL",0.676823094036297,0.477223974,76,19.09,132,{"v":5.28937e-28,"d":"5.29E-28"},{"v":1.10979e-22,"d":"1.11E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex",{"v":3.7e-19,"d":"3.70E-19"},"rs34121855;rs35348663;rs35489648;7:73042302_GCTTT_G;rs42122;rs799167;7:73047677_GT_G;rs42122:7:73042302_GCTTT_G:rs34121855;rs35348663:rs34121855",19]
["ENSG00000176428","VPS37D",7,73082155,73086442,1,"protein_coding",155382,"VPS37D",0.656347210550458,"NA",0,0,50,{"v":2.29153E-10,"d":"2.29E-10"},{"v":1.34286e-08,"d":"1.34E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":3.7e-19,"d":"3.70E-19"},"rs34121855;rs35348663;7:73042302_GCTTT_G;rs799167;rs35348663:rs34121855;rs35348663:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs35489648:rs34121855:rs34121855",19]
["ENSG00000106089","STX1A",7,73113536,73134002,-1,"protein_coding",6804,"STX1A",0.910475757164848,-0.07051921,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-18,"d":"1.10E-18"},"rs34121855;rs35348663:7:73042302_GCTTT_G",19]
["ENSG00000106077","ABHD11",7,73150424,73153197,-1,"protein_coding",83451,"ABHD11",{"v":9.03291221619057e-06,"d":"9.03E-06"},0.148517676,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.8e-19,"d":"4.80E-19"},"7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs34121855;rs35348663:rs35489648:rs34121855:rs34121855",19]
["ENSG00000165215","CLDN3",7,73183328,73184600,-1,"protein_coding",1365,"CLDN3",0.678537320145956,-0.798792708,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":4.8e-19,"d":"4.80E-19"},"rs34121855",19]
["ENSG00000165171","WBSCR27",7,73248920,73256865,-1,"protein_coding",155368,"WBSCR27",0.0679116625114122,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.8E-18,"d":"6.80E-18"},"rs35348663:rs34121855;rs35348663:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs35489648",19]
["ENSG00000175877","WBSCR28",7,73275489,73280223,1,"protein_coding",135886,"WBSCR28",{"v":1.58800503099146E-6,"d":"1.59E-06"},0.424364093,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.9e-17,"d":"7.90E-17"},"rs34121855;rs35348663:7:73042302_GCTTT_G;rs42122",19]
["ENSG00000106683","LIMK1",7,73497263,73536855,1,"protein_coding",3984,"LIMK1",0.990896287164463,-0.781218183,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.1e-18,"d":"1.10E-18"},"7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:7:73042302_GCTTT_G",19]
["ENSG00000106682","EIF4H",7,73588575,73611431,1,"protein_coding",7458,"EIF4H",0.922544880243499,-1.500430355,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":6.6e-18,"d":"6.60E-18"},"7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs34121855;rs35348663",19]
["ENSG00000086730","LAT2",7,73613982,73644161,1,"protein_coding",7462,"LAT2",0.000691063098880473,-0.479096813,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.3e-18,"d":"7.30E-18"},"rs799167:7:73042302_GCTTT_G:rs34121855",19]
["ENSG00000049541","RFC2",7,73645829,73668774,-1,"protein_coding",5982,"RFC2",{"v":4.04212746398499e-05,"d":"4.04E-05"},-0.396975582,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":5.8e-17,"d":"5.80E-17"},"7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663",19]
["ENSG00000106665","CLIP2",7,73703805,73820273,1,"protein_coding",7461,"CLIP2",0.999881647285659,0.2522342,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.1e-18,"d":"1.10E-18"},"7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:7:73042302_GCTTT_G",19]
["ENSG00000164816","DEFA5",8,6912831,6914256,-1,"protein_coding",1670,"DEFA5",1.00681038440857E-4,0.021331924,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.5e-07,"d":"1.50E-07"},"rs615632",21]
["ENSG00000198129","DEFB107B",8,7353368,7366833,1,"protein_coding",503614,"DEFB107B","NA",-0.203867911,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.8e-08,"d":"2.80E-08"},"rs2976940",20]
["ENSG00000182319","SGK223",8,8175258,8244008,-1,"protein_coding",157285,"PRAG1",{"v":5.12369052262778e-20,"d":"5.12E-20"},"NA",9,18.02,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-09,"d":"8.20E-09"},"rs2976940",20]
["ENSG00000253958","CLDN23",8,8559448,8561616,1,"protein_coding",137075,"CLDN23",{"v":2.46842024128337E-5,"d":"2.47E-05"},1.939020665,0,0,6,{"v":3.82989e-06,"d":"3.83E-06"},{"v":1.33858E-5,"d":"1.34E-05"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":8.2e-09,"d":"8.20E-09"},"rs2976940;rs4240623;rs11774915",20]
["ENSG00000147324","MFHAS1",8,8640864,8751155,-1,"protein_coding",9258,"MFHAS1",{"v":2.22820045783843E-5,"d":"2.23E-05"},0.9551839,0,0,13,{"v":8.24532e-11,"d":"8.25E-11"},{"v":2.21586E-22,"d":"2.22E-22"},"GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-25,"d":"1.50E-25"},"rs2976940;rs11779019;rs615632;rs7004769:rs4240623:rs1461729;rs12546198:rs2976940:rs1461729:rs34290760:rs11774915:rs615632","20:21:00"]
["ENSG00000104626","ERI1",8,8859657,8974256,1,"protein_coding",90459,"ERI1",0.000454685197816091,0.949360106,0,0,74,{"v":7.26387e-08,"d":"7.26E-08"},{"v":1.19077e-06,"d":"1.19E-06"},"GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-25,"d":"1.50E-25"},"rs2976940;rs1461729;rs11774915;rs12546198;rs11779019;rs615632;rs2976940:rs1461729:rs4240623:rs7004769:rs34290760:rs11774915:rs1461729;rs12546198:8:9220256_CT_C:rs922049:rs12546198:rs12546198;rs11786900:rs11779019:rs615632:rs7005363:rs2409784;rs11250098:rs11786900","20:21:00"]
["ENSG00000173281","PPP1R3B",8,8993765,9009084,-1,"protein_coding",79660,"PPP1R3B",0.0229191412335762,3.70852971,0,0,38,{"v":2.03833e-08,"d":"2.04E-08"},{"v":2.14339E-8,"d":"2.14E-08"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Mesendoderm",{"v":1.5e-25,"d":"1.50E-25"},"rs2976940;rs922049;rs615632;rs7004769:rs1461729:rs4240623:rs34290760:rs11774915:rs1461729;rs12546198","20:21:00"]
["ENSG00000253426","RP11-10A14.4",8,9009252,9025646,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.5e-25,"d":"1.50E-25"},"rs7004769:rs1461729:rs4240623:rs34290760:rs11774915:rs1461729;rs12546198",20]
["ENSG00000173273","TNKS",8,9413424,9639856,1,"protein_coding",8658,"TNKS",0.777115954184058,1.637267498,0,0,13,{"v":7.43105e-08,"d":"7.43E-08"},0.00127623,"GTEx/v8/Liver","+","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-25,"d":"1.50E-25"},"rs1461729;rs12546198;rs2976940:rs11786900:rs11779019:rs7004769:rs1461729:rs4240623:rs34290760:rs11774915:rs1461729;rs12546198:8:9220256_CT_C:rs922049:rs12546198:rs12546198;rs11786900",20]
["ENSG00000175806","MSRA",8,9911778,10286401,1,"protein_coding",4482,"MSRA",{"v":1.69976100303061E-6,"d":"1.70E-06"},0.601529643,26,14.76,41,{"v":5.44014e-07,"d":"5.44E-07"},{"v":1.77758E-6,"d":"1.78E-06"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.3e-09,"d":"4.30E-09"},"rs615632;rs7005363;rs11250098;rs2409784;rs4240674;rs615632:rs7005363;rs615632:rs7005363:rs11250098",21]
["ENSG00000184647","PRSS55",8,10383056,10411676,1,"protein_coding",203074,"PRSS55",{"v":1.2335690846368e-08,"d":"1.23E-08"},0.255257421,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.5e-07,"d":"1.50E-07"},"rs615632",21]
["ENSG00000183638","RP1L1",8,10463859,10569697,-1,"protein_coding",94137,"RP1L1","NA",1.244966111,0,0,173,{"v":4.49213e-08,"d":"4.49E-08"},{"v":5.58954e-13,"d":"5.59E-13"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","IMR90:Mesendoderm:Trophoblast-like_Cell",{"v":2.1e-08,"d":"2.10E-08"},"rs11250098;rs2409784;rs615632:rs11250098:rs2409784;rs11250098:rs7005363",21]
["ENSG00000171060","C8orf74",8,10530147,10558103,1,"protein_coding",203076,"C8orf74",{"v":1.01040579381024E-11,"d":"1.01E-11"},0.574612154,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.6e-06,"d":"3.60E-06"},"rs2409784;rs11250098",21]
["ENSG00000171056","SOX7",8,10581278,10697357,-1,"protein_coding",83595,"SOX7",0.131241610927833,0.638029508,0,0,19,{"v":3.04109e-06,"d":"3.04E-06"},{"v":1.68524e-08,"d":"1.69E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-09,"d":"5.30E-09"},"rs615632;rs11250098;rs2409784;rs11250098:rs4240674:rs615632:rs2409784;rs11250098:rs7005363",21]
["ENSG00000258724","SOX7",8,10582909,10697357,-1,"protein_coding",83595,"SOX7","NA",0.638029508,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-09,"d":"5.30E-09"},"rs11250098:rs4240674:rs615632:rs2409784;rs11250098:rs7005363",21]
["ENSG00000254093","PINX1",8,10622473,10697394,-1,"protein_coding",54984,"PINX1",{"v":4.9427916851122e-09,"d":"4.94E-09"},-0.063935492,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-09,"d":"5.30E-09"},"rs11250098:rs4240674:rs615632:rs2409784;rs11250098:rs7005363",21]
["ENSG00000171044","XKR6",8,10753555,11058875,-1,"protein_coding",286046,"XKR6",0.956776701241562,0.199430911,232,14.04,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.5e-25,"d":"1.50E-25"},"rs11250098;rs2409784;rs4240674;rs11250098:rs4240674:rs2409784;rs11250098:rs2976940:rs7004769:rs1461729:rs4240623:rs34290760:rs11774915:rs1461729;rs12546198:rs615632:rs7005363:rs34365278:rs34365278","20:21:00"]
["ENSG00000215346","AF131215.5",8,10983980,10987745,-1,"protein_coding","NA","NA","NA","NA",14,4.532,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-08,"d":"1.10E-08"},"rs11250098;rs11250098:rs2409784;rs11250098:rs4240674",21]
["ENSG00000104643","MTMR9",8,11141925,11185646,1,"protein_coding",66036,"MTMR9",0.210866148969841,1.579316819,3,2.582,75,{"v":4.52643e-07,"d":"4.53E-07"},{"v":4.11807E-6,"d":"4.12E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Coronary","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.9e-09,"d":"9.90E-09"},"rs2409784;rs11250098;rs615632;rs7005363;rs4240674;rs11250098:rs2409784;rs11250098:rs4240674:rs615632:rs2409784:rs7005363",21]
["ENSG00000177710","SLC35G5",8,11188397,11189717,1,"protein_coding",83650,"SLC35G5",0.0274846347511103,0.517541682,0,0,122,{"v":8.45794e-07,"d":"8.46E-07"},{"v":1.15275e-05,"d":"1.15E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","+","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs11250098;rs2409784;rs615632;rs11250098:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs1692821:rs4841600:rs11786900:rs11779019:rs615632:rs7005363:rs4240674:rs2409784:rs7005363","20:21:00"]
["ENSG00000184608","C8orf12",8,11225911,11296167,1,"protein_coding",83656,"C8orf12",0.311268910075586,"NA",0,0,181,{"v":6.74532e-10,"d":"6.75E-10"},{"v":1.86718e-33,"d":"1.87E-33"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs11250098;rs34365278;rs7005363;rs2409784;rs1692821;rs11250098:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs2409784:rs1692821:rs4841600",21]
["ENSG00000154319","FAM167A",8,11278972,11332224,-1,"protein_coding",83648,"FAM167A",0.000192997889999534,0.911877562,23,10.02,10,{"v":3.43098e-05,"d":"3.43E-05"},0.0226044,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-09,"d":"1.10E-09"},"rs34365278;rs2409784;rs11250098;rs2409784:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs1692821:rs4841600",21]
["ENSG00000136573","BLK",8,11351510,11422113,1,"protein_coding",640,"BLK",{"v":2.86165843035065e-07,"d":"2.86E-07"},-0.27366236,64,11.59,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-09,"d":"1.10E-09"},"rs2409784;rs11250098;rs2409784:rs34365278:rs34365278;rs2409784:rs1692821:rs4841600:rs2409784",21]
["ENSG00000136574","GATA4",8,11534468,11617511,1,"protein_coding",2626,"GATA4",0.802155487205778,0.664928994,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs34365278:rs34365278;rs2409784:rs2409784;rs11250098:rs2409784:rs1692821:rs4841600",21]
["ENSG00000255394","C8orf49",8,11618896,11620309,1,"protein_coding",606553,"C8orf49","NA","NA",0,0,26,{"v":2.83733e-06,"d":"2.84E-06"},{"v":2.0822e-15,"d":"2.08E-15"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs11250098;rs2409784;rs2409784:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs1692821:rs4841600",21]
["ENSG00000154328","NEIL2",8,11627148,11644855,1,"protein_coding",252969,"NEIL2",{"v":2.11099583099423e-09,"d":"2.11E-09"},2.689044542,0,0,233,{"v":1.06746E-8,"d":"1.07E-08"},{"v":1.67472E-21,"d":"1.67E-21"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs2409784;rs11250098;rs4240674;rs34365278;rs1692821:rs2409784;rs11250098:rs2409784:rs34365278:rs34365278;rs2409784:rs4841600",21]
["ENSG00000079459","FDFT1",8,11653082,11696818,1,"protein_coding",2222,"FDFT1","NA",1.285658937,43,12.24,356,{"v":9.00688e-25,"d":"9.01E-25"},{"v":1.29552E-43,"d":"1.30E-43"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs4841600;rs1692821;rs11250098;rs2409784;rs34365278;rs4240674;rs1692821:rs4841600:rs2409784:rs34365278:rs34365278",21]
["ENSG00000255046","RP11-297N6.4",8,11655437,11660077,-1,"protein_coding","NA","NA","NA","NA",1,1.151,72,{"v":9.70452e-07,"d":"9.70E-07"},{"v":5.37179e-09,"d":"5.37E-09"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs4841600;rs11250098;rs4240674;rs2409784;rs1692821:rs4841600:rs2409784:rs34365278:rs34365278",21]
["ENSG00000164733","CTSB",8,11700033,11726957,-1,"protein_coding",1508,"CTSB","NA",4.805364716,48,12.24,372,{"v":1.06701E-48,"d":"1.07E-48"},{"v":3.41996e-40,"d":"3.42E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs1692821;rs4841600;rs11250098;rs2409784;rs4240674;rs34365278;rs1692821:rs4841600:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs2409784",21]
["ENSG00000205884","DEFB136",8,11831446,11832108,-1,"protein_coding",613210,"DEFB136",0.0340000990200746,0.27516663,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs2409784:rs11250098:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs1692821:rs4841600",21]
["ENSG00000205883","DEFB135",8,11839830,11842099,1,"protein_coding",613209,"DEFB135",{"v":1.31655071986469e-06,"d":"1.32E-06"},0.082643215,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs2409784:rs1692821:rs11250098:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784:rs4841600",21]
["ENSG00000205882","DEFB134",8,11850692,11853821,-1,"protein_coding",613211,"DEFB134",0.0322373411768572,0.812797609,0,0,203,{"v":1.67961e-12,"d":"1.68E-12"},{"v":1.26369e-17,"d":"1.26E-17"},"GTEx/v8/Pancreas","-","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":7.6e-09,"d":"7.60E-09"},"rs11250098;rs2409784;rs34365278;rs4841600;rs2409784:rs11250098:rs2409784;rs11250098:rs34365278:rs34365278",21]
["ENSG00000255098","RP11-481A20.11",8,11870545,11873043,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":7.6e-09,"d":"7.60E-09"},"rs2409784:rs11250098:rs2409784;rs11250098:rs34365278:rs34365278;rs2409784",21]
["ENSG00000186523","FAM86B1",8,12039605,12051642,-1,"protein_coding",85002,"FAM86B1",0.744460341331624,-0.801740789,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.6e-08,"d":"1.60E-08"},"rs4841600:rs1692821",21]
["ENSG00000232948","DEFB130",8,12168471,12175825,-1,"protein_coding",245940,"DEFB130","NA",0.318396342,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.6e-06,"d":"3.60E-06"},"rs2409784",21]
["ENSG00000156006","NAT2",8,18248755,18258728,1,"protein_coding",10,"NAT2",0.0226078662097717,0.267314509,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.3e-08,"d":"2.30E-08"},"rs7816447",22]
["ENSG00000156011","PSD3",8,18384811,18942240,-1,"protein_coding",23362,"PSD3",0.851705649436322,1.354305318,0,0,0,"NA","NA","NA","NA","Yes","Aorta",{"v":4.1e-13,"d":"4.10E-13"},"rs7816447",22]
["ENSG00000104611","SH2D4A",8,19171128,19253729,1,"protein_coding",63898,"SH2D4A",{"v":1.53114480649588e-18,"d":"1.53E-18"},-0.083318155,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.1e-13,"d":"4.10E-13"},"rs7816447:rs7816447;rs73600084:rs73600084:rs287;rs11986942:rs11986942",22]
["ENSG00000147408","CSGALNACT1",8,19261672,19615540,-1,"protein_coding",55790,"CSGALNACT1",{"v":6.87751081149391e-05,"d":"6.88E-05"},0.406270981,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.1E-13,"d":"7.10E-13"},"rs7816447:rs7816447;rs73600084:rs73600084:rs287;rs11986942:rs11986942",22]
["ENSG00000104613","INTS10",8,19674651,19709594,1,"protein_coding",55174,"INTS10",0.984216594645776,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.1e-13,"d":"4.10E-13"},"rs7816447:rs7816447;rs73600084:rs73600084:rs287;rs11986942:rs11986942",22]
["ENSG00000175445","LPL",8,19759228,19824769,1,"protein_coding",4023,"LPL",{"v":3.33727737763241e-06,"d":"3.34E-06"},1.047176611,44,50,88,{"v":4.28361e-08,"d":"4.28E-08"},1.73182E-4,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-13,"d":"4.10E-13"},"rs7816447;rs287;rs11986942;rs301;rs73600084;rs7816447:rs7816447;rs73600084:rs73600084:rs287;rs11986942:rs11986942:rs287:rs301",22]
["ENSG00000036565","SLC18A1",8,20002366,20040717,-1,"protein_coding",6570,"SLC18A1",{"v":1.8888318573672e-14,"d":"1.89E-14"},0.247527783,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Mesenchymal_Stem_Cell",{"v":7.1E-13,"d":"7.10E-13"},"rs7816447:rs7816447;rs73600084:rs73600084:rs287;rs11986942:rs11986942",22]
["ENSG00000147416","ATP6V1B2",8,20054878,20084330,1,"protein_coding",526,"ATP6V1B2",0.991448562707497,-0.741850309,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.1E-13,"d":"7.10E-13"},"rs7816447:rs7816447;rs73600084:rs73600084:rs287;rs11986942:rs11986942",22]
["ENSG00000181690","PLAG1",8,57073463,57123883,-1,"protein_coding",5324,"PLAG1",0.829917236319924,-1.103597026,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":5.9e-10,"d":"5.90E-10"},"rs6471717",23]
["ENSG00000170791","CHCHD7",8,57124245,57131357,1,"protein_coding",79145,"CHCHD7",0.387975837016134,-0.333440097,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":5.9e-10,"d":"5.90E-10"},"rs6471717",23]
["ENSG00000169122","FAM110B",8,58907068,59116838,1,"protein_coding",90362,"FAM110B",0.172625630799022,-0.286252494,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5.9e-10,"d":"5.90E-10"},"rs6471717",23]
["ENSG00000215114","UBXN2B",8,59323823,59364060,1,"protein_coding",137886,"UBXN2B",0.487567803186615,-0.274791059,17,15.8,27,{"v":2.12222e-07,"d":"2.12E-07"},{"v":7.71599e-24,"d":"7.72E-24"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Liver","+","Yes","Mesendoderm",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717;rs55704109",23]
["ENSG00000167910","CYP7A1",8,59402737,59412795,-1,"protein_coding",1581,"CYP7A1",0.00345536122276857,-0.121517501,10,20.8,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717;rs6471717:rs55704109:rs6471717;rs55704109",23]
["ENSG00000137575","SDCBP",8,59465483,59495419,1,"protein_coding",6386,"SDCBP",0.000811571828670198,-0.857907679,0,0,30,{"v":1.23518E-12,"d":"1.24E-12"},{"v":1.92649e-11,"d":"1.93E-11"},"GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","No","NA",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717;rs55704109",23]
["ENSG00000035681","NSMAF",8,59496063,59572403,-1,"protein_coding",8439,"NSMAF",{"v":3.1837468420093e-08,"d":"3.18E-08"},"NA",0,0,28,{"v":2.50444e-06,"d":"2.50E-06"},0.000175602,"GTEx/v8/Artery_Aorta","-","No","NA",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717;rs55704109",23]
["ENSG00000178538","CA8",8,61099906,61193971,-1,"protein_coding",767,"CA8",0.783927466808709,0.803920845,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717:rs6471717;rs55704109:rs55704109",23]
["ENSG00000104388","RAB2A",8,61429416,61536186,1,"protein_coding",5862,"RAB2A",0.970735512688083,-0.412665448,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717:rs6471717;rs55704109",23]
["ENSG00000171316","CHD7",8,61591337,61779465,1,"protein_coding",55636,"CHD7",0.999999999999751,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.9e-13,"d":"6.90E-13"},"rs6471717;rs55704109:rs6471717",23]
["ENSG00000189376","C8orf76",8,124232196,124253638,-1,"protein_coding",84933,"C8orf76",{"v":1.71944218858493e-05,"d":"1.72E-05"},-0.020072916,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.5e-09,"d":"3.50E-09"},"rs4360309",24]
["ENSG00000259305","ZHX1-C8ORF76",8,124238431,124279627,-1,"protein_coding",100533106,"ZHX1-C8ORF76",0.00105203127523669,-0.36802306,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.5e-09,"d":"3.50E-09"},"rs4360309",24]
["ENSG00000170881","RNF139",8,125486979,125500155,1,"protein_coding",11236,"RNF139",0.0608738334958745,-0.469220523,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.5e-09,"d":"3.50E-09"},"rs4360309",24]
["ENSG00000147687","TATDN1",8,125500726,125551699,-1,"protein_coding",83940,"TATDN1",{"v":1.72640600686597e-08,"d":"1.73E-08"},0.357863168,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6E-34,"d":"6.00E-34"},"rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651:rs4360309",24]
["ENSG00000147684","NDUFB9",8,125551344,125580751,1,"protein_coding",4715,"NDUFB9",0.0428894468164687,-0.016587227,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6E-34,"d":"6.00E-34"},"rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651:rs4360309",24]
["ENSG00000180938","ZNF572",8,125985540,125991631,1,"protein_coding",137209,"ZNF572",0.000651450621070101,-0.137914163,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":6E-34,"d":"6.00E-34"},"rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651",24]
["ENSG00000104549","SQLE",8,126010739,126034525,1,"protein_coding",6713,"SQLE",0.91297067975512,1.171693492,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6E-34,"d":"6.00E-34"},"rs4360309:rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651",24]
["ENSG00000164961","KIAA0196",8,126036502,126104082,-1,"protein_coding",9897,"KIAA0196",{"v":4.81024990398197e-13,"d":"4.81E-13"},-0.762157486,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6E-34,"d":"6.00E-34"},"rs2385114:rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651:rs4360309",24]
["ENSG00000156831","NSMCE2",8,126103921,126379362,1,"protein_coding",286053,"NSMCE2",0.0724507212755206,-0.471934498,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6E-34,"d":"6.00E-34"},"rs2385114:rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651:rs4360309",24]
["ENSG00000173334","TRIB1",8,126442563,126450647,1,"protein_coding",10221,"TRIB1",0.606587656595858,-0.456914247,12,6.894,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":9.6e-11,"d":"9.60E-11"},"rs2385114;rs4871598;rs12674939;rs4360309:rs2385114",24]
["ENSG00000136997","MYC",8,128747680,128753674,1,"protein_coding",4609,"MYC","NA",-0.253124713,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":6E-34,"d":"6.00E-34"},"rs112875651;rs2954021:rs2954038:rs35309034;rs12674939:rs2954021:rs72655677:8:126490499_TA_T:rs35309034:8:126504383_CCACCAT_C:rs112875651",24]
["ENSG00000153714","LURAP1L",9,12775020,12822130,1,"protein_coding",286343,"LURAP1L",0.0766242694095508,0.220603476,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000107186","MPDZ",9,13105703,13279589,-1,"protein_coding",8777,"MPDZ","NA",0.345884525,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000175893","ZDHHC21",9,14611069,14693469,-1,"protein_coding",340481,"ZDHHC21",0.0512303788505532,1.009801353,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000147869","CER1",9,14719722,14722715,-1,"protein_coding",9350,"CER1",{"v":2.57822812120588e-05,"d":"2.58E-05"},-0.00799085,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000164946","FREM1",9,14734664,14910993,-1,"protein_coding",158326,"FREM1","NA",2.024228525,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000155158","TTC39B",9,15163620,15307358,-1,"protein_coding",158219,"TTC39B",{"v":1.06813738722138E-11,"d":"1.07E-11"},0.056260627,44,16.34,40,{"v":7.39737e-14,"d":"7.40E-14"},{"v":1.2245e-09,"d":"1.22E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049;rs535772;rs4008004",25]
["ENSG00000164975","SNAPC3",9,15422702,15465951,1,"protein_coding",6619,"SNAPC3",{"v":5.53901197607186e-05,"d":"5.54E-05"},1.456738075,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8e-10,"d":"2.80E-10"},"rs535772:rs2849049:rs4008004;rs2849049:rs4008004",25]
["ENSG00000164985","PSIP1",9,15464064,15511017,-1,"protein_coding",11168,"PSIP1",0.946350057562085,0.382466325,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000164989","CCDC171",9,15552895,16061661,1,"protein_coding",203238,"CCDC171","NA",0.216049891,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8e-10,"d":"2.80E-10"},"rs2849049:rs535772:rs4008004;rs2849049:rs4008004",25]
["ENSG00000155833","CYLC2",9,105757593,105780770,1,"protein_coding",1539,"CYLC2",{"v":5.14081582239004e-07,"d":"5.14E-07"},1.40861542,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":4.8e-12,"d":"4.80E-12"},"rs2245793:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282:rs11791258:rs67740686:rs4149273",26]
["ENSG00000136783","NIPSNAP3A",9,107509969,107522403,1,"protein_coding",25934,"NIPSNAP3A",{"v":1.63591359584979e-05,"d":"1.64E-05"},0.213980976,0,0,13,{"v":9.99937e-08,"d":"1.00E-07"},{"v":2.58137e-25,"d":"2.58E-25"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage","-","No","NA",{"v":4.3e-09,"d":"4.30E-09"},"rs3824477;rs2245793",26]
["ENSG00000165028","NIPSNAP3B",9,107526438,107539738,1,"protein_coding",55335,"NIPSNAP3B",0.0238829678663823,-0.281408699,2,9.246,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8e-12,"d":"4.80E-12"},"rs2245793;rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282:rs11791258:rs67740686:rs4149273",26]
["ENSG00000165029","ABCA1",9,107543283,107690518,-1,"protein_coding",19,"ABCA1",0.00165880319635912,0.082774215,130,16.72,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.7e-26,"d":"8.70E-26"},"rs2245793;rs3824477;rs4149307;rs36050540;9:107603722_AAAAAAG_A;rs12004282;rs11791258;rs67740686;rs4149273;rs13284054;rs2740488;rs73664373;rs1800978;rs2254819;rs3905001;rs2437818;rs4149273:rs1800978:rs73664373:rs2740488:rs4149273:rs2254819:rs3905001:rs13284054:rs13284054;rs67740686:rs67740686:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282:rs11791258",26]
["ENSG00000070214","SLC44A1",9,108006903,108201452,1,"protein_coding",23446,"SLC44A1",0.999253571367297,-0.569151,0,0,9,{"v":1.76327e-06,"d":"1.76E-06"},0.00432065,"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-26,"d":"8.70E-26"},"rs67740686;rs13284054;rs12004282:rs11791258;rs12004282:rs2740488;rs4149273:rs1800978:rs73664373:rs2740488:rs4149273:rs2254819:rs3905001:rs13284054:rs13284054;rs67740686:rs67740686:rs36050540:9:107603722_AAAAAAG_A:rs11791258:rs2245793:rs3824477:rs4149307:rs2437818",26]
["ENSG00000106701","FSD1L",9,108210077,108314714,1,"protein_coding",83856,"FSD1L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.7e-26,"d":"8.70E-26"},"rs12004282:rs11791258;rs12004282:rs11791258:rs67740686:rs4149273:rs2740488;rs4149273:rs1800978:rs73664373:rs2740488:rs2254819:rs3905001:rs13284054:rs13284054;rs67740686:rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs2437818",26]
["ENSG00000106692","FKTN",9,108320411,108403399,1,"protein_coding",2218,"FKTN",0.000192375264435551,-1.003484248,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.8e-12,"d":"4.80E-12"},"rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282:rs11791258:rs67740686:rs4149273",26]
["ENSG00000186051","TAL2",9,108424738,108425367,1,"protein_coding",6887,"TAL2",0.488535069507167,0.093363904,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.7e-26,"d":"8.70E-26"},"rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282:rs11791258:rs67740686:rs4149273:rs13284054;rs67740686:rs2740488;rs4149273:rs73664373:rs13284054:rs1800978:rs2740488:rs2254819:rs3905001:rs2437818",26]
["ENSG00000095209","TMEM38B",9,108456825,108538893,1,"protein_coding",55151,"TMEM38B",0.1687999661801,0.890196099,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.8e-12,"d":"4.80E-12"},"rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282:rs11791258:rs67740686:rs4149273",26]
["ENSG00000125485","DDX31",9,135468384,135545788,-1,"protein_coding",64794,"DDX31",{"v":2.75575676923568e-06,"d":"2.76E-06"},-0.899017337,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.8e-16,"d":"2.80E-16"},"rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",27]
["ENSG00000125484","GTF3C4",9,135545422,135570342,1,"protein_coding",9329,"GTF3C4",0.0149762555569875,0.796705006,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.8e-16,"d":"2.80E-16"},"rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",27]
["ENSG00000148308","GTF3C5",9,135906076,135933890,1,"protein_coding",9328,"GTF3C5",0.00274002234197739,-0.524089361,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":2.5e-07,"d":"2.50E-07"},"rs56343119;rs28538967:rs56343119",27]
["ENSG00000171102","OBP2B",9,136080664,136084630,-1,"protein_coding",29989,"OBP2B",0.182972936041483,-0.121398936,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.8e-16,"d":"2.80E-16"},"rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",27]
["ENSG00000148296","SURF6",9,136197552,136203235,-1,"protein_coding",6838,"SURF6",{"v":8.12446562293265e-05,"d":"8.12E-05"},-0.437227567,0,0,1,{"v":8.97688E-5,"d":"8.98E-05"},{"v":6.44478E-55,"d":"6.44E-55"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3E-9,"d":"3.00E-09"},"rs11244061;rs56343119:rs28538967",27]
["ENSG00000148297","MED22",9,136205160,136214986,-1,"protein_coding",6837,"MED22",0.00632213991393259,-0.130266294,3,8.347,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs56343119;rs28538967;rs28538967:rs56343119",27]
["ENSG00000148303","RPL7A",9,136215069,136218281,1,"protein_coding",6130,"RPL7A",0.979405408797334,"NA",3,8.347,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs56343119;rs28538967;rs28538967:rs56343119",27]
["ENSG00000148290","SURF1",9,136218610,136223552,-1,"protein_coding",6834,"SURF1",{"v":1.02063910629184E-13,"d":"1.02E-13"},"NA",3,8.347,36,{"v":9.03612e-27,"d":"9.04E-27"},{"v":2.67588e-56,"d":"2.68E-56"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-16,"d":"2.80E-16"},"rs56343119;rs28538967;rs115478735;rs550057;rs11244061;rs56343119:rs28538967",27]
["ENSG00000148291","SURF2",9,136223428,136228045,1,"protein_coding",6835,"SURF2",{"v":3.07087198881956e-07,"d":"3.07E-07"},"NA",4,8.347,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967;rs56343119:rs28538967",27]
["ENSG00000148248","SURF4",9,136228325,136242970,-1,"protein_coding",6836,"SURF4",0.686424182931678,-0.490474887,3,3.697,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967",27]
["ENSG00000198870","C9orf96",9,136243117,136271220,1,"protein_coding",169436,"C9orf96",{"v":2.54706971388686e-16,"d":"2.55E-16"},"NA",7,12.15,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967",27]
["ENSG00000148300","REXO4",9,136271186,136283164,-1,"protein_coding",57109,"REXO4",{"v":9.99455362636825e-06,"d":"9.99E-06"},1.530845821,4,12.15,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967;rs28538967:rs56343119:rs28538967",27]
["ENSG00000160323","ADAMTS13",9,136279478,136324508,1,"protein_coding",11093,"ADAMTS13",{"v":7.88296728194754e-11,"d":"7.88E-11"},-0.276084391,11,16.74,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs56343119;rs28538967;rs28538967:rs28538967:rs56343119",27]
["ENSG00000160325","CACFD1",9,136325089,136335970,1,"protein_coding",11094,"CACFD1",0.00574676872876184,"NA",8,16.74,4,{"v":1.14306E-5,"d":"1.14E-05"},{"v":1.39999e-07,"d":"1.40E-07"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-16,"d":"2.80E-16"},"rs28538967;rs56343119;rs28538967:rs56343119;rs28538967:rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",27]
["ENSG00000160326","SLC2A6",9,136336217,136344259,-1,"protein_coding",11182,"SLC2A6",0.000366664150450035,-0.033260488,5,16.74,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-16,"d":"2.80E-16"},"rs56343119;rs28538967:rs28538967:rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",27]
["ENSG00000187616","TMEM8C",9,136379708,136393734,-1,"protein_coding",389827,"TMEM8C",2.16915928417017E-3,0.106132843,0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-16,"d":"2.80E-16"},"rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061:rs56343119;rs28538967:rs28538967",27]
["ENSG00000197859","ADAMTSL2",9,136397286,136440641,1,"protein_coding",9719,"ADAMTSL2",0.0710586670580913,"NA",0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-16,"d":"2.80E-16"},"rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061:rs56343119;rs28538967:rs28538967",27]
["ENSG00000196990","FAM163B",9,136444079,136451319,-1,"protein_coding",642968,"FAM163B",0.428150995206124,-0.470114741,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.8e-16,"d":"2.80E-16"},"rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",27]
["ENSG00000123453","SARDH",9,136528682,136605077,-1,"protein_coding",1757,"SARDH",{"v":8.19688048123126e-10,"d":"8.20E-10"},-0.160035756,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":8.1e-07,"d":"8.10E-07"},"rs56343119",27]
["ENSG00000169925","BRD3",9,136895427,136933657,-1,"protein_coding",8019,"BRD3",0.766979379296961,1.798261326,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.5e-07,"d":"2.50E-07"},"rs56343119;rs28538967",27]
["ENSG00000196793","ZNF239",10,44051792,44070066,-1,"protein_coding",8187,"ZNF239",0.000867929253552217,0.570932296,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.3e-10,"d":"5.30E-10"},"rs148063610;rs10793624:rs148063610;rs150231142:rs148063610;rs150231142;rs10793624",28]
["ENSG00000169740","ZNF32",10,44139307,44144304,-1,"protein_coding",7580,"ZNF32",0.276205822566686,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":3.4e-10,"d":"3.40E-10"},"rs148063610;rs10793624:rs148063610;rs150231142:rs148063610;rs150231142",28]
["ENSG00000187783","TMEM72",10,45406648,45432450,1,"protein_coding",643236,"TMEM72",0.49453096966628,1.768118555,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2e-09,"d":"2.00E-09"},"rs148063610;rs150231142;rs10793624",28]
["ENSG00000165507","C10orf10",10,45466429,45474258,-1,"protein_coding",11067,"C10orf10",{"v":3.86908584231525e-05,"d":"3.87E-05"},0.524652874,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.9E-10,"d":"6.90E-10"},"rs148063610;rs150231142:rs148063610;rs150231142;rs10793624:rs148063610;rs10793624",28]
["ENSG00000165511","C10orf25",10,45493146,45496336,-1,"protein_coding",220979,"C10orf25",0.012567313038728,-0.929200156,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:hESC",{"v":3.4e-10,"d":"3.40E-10"},"rs148063610;rs150231142;rs10793624:rs148063610;rs10793624:rs148063610:rs148063610",28]
["ENSG00000165512","ZNF22",10,45495923,45500774,1,"protein_coding",7570,"ZNF22",0.126684327200881,-0.107262233,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:hESC",{"v":3.4e-10,"d":"3.40E-10"},"rs148063610;rs150231142;rs10793624:rs148063610;rs10793624:rs148063610:rs148063610",28]
["ENSG00000256574","OR13A1",10,45798102,45811056,-1,"protein_coding",79290,"OR13A1",2.12216731545614E-4,0.297808605,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.3e-08,"d":"1.30E-08"},"rs148063610;rs150231142;rs10793624",28]
["ENSG00000012779","ALOX5",10,45869661,45941561,1,"protein_coding",240,"ALOX5",1.64439332581691E-3,"NA",0,0,10,{"v":8.9692e-05,"d":"8.97E-05"},{"v":5.70457e-10,"d":"5.70E-10"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Left_Ventricle",{"v":3.2e-10,"d":"3.20E-10"},"rs148063610;rs150231142;rs150231142:rs148063610;rs10793624:rs148063610",28]
["ENSG00000165406","2008-03-01",10,45950035,46090354,-1,"protein_coding",220972,"2008-03-01",{"v":1.37263384630584e-05,"d":"1.37E-05"},-0.165648458,58,15.6,41,{"v":6.27958e-08,"d":"6.28E-08"},{"v":2.41813e-15,"d":"2.42E-15"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":1.2E-10,"d":"1.20E-10"},"rs148063610;rs150231142;rs10793624",28]
["ENSG00000172671","ZFAND4",10,46111043,46168228,-1,"protein_coding",93550,"ZFAND4",0.00925156548332018,0.078714079,6,6.821,22,{"v":4.87453e-09,"d":"4.87E-09"},{"v":9.0563e-26,"d":"9.06E-26"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops",{"v":5.1E-10,"d":"5.10E-10"},"rs148063610;rs150231142;rs10793624;rs150231142:rs148063610;rs10793624:rs148063610;rs10793624:rs10793624",28]
["ENSG00000172661","FAM21C",10,46222648,46288409,1,"protein_coding",253725,"FAM21C","NA",0.129559906,5,6.848,64,{"v":1.30119E-32,"d":"1.30E-32"},{"v":1.88308e-34,"d":"1.88E-34"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":2.7E-10,"d":"2.70E-10"},"rs148063610;rs150231142;rs10793624",28]
["ENSG00000188234","AGAP4",10,46321042,46349323,-1,"protein_coding",119016,"AGAP4","NA","NA",0,0,5,{"v":9.24652e-05,"d":"9.25E-05"},{"v":2.53526e-107,"d":"2.54E-107"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":3.2e-10,"d":"3.20E-10"},"rs148063610;rs150231142",28]
["ENSG00000204174","NPY4R",10,47083534,47088320,1,"protein_coding",5540,"NPY4R",{"v":6.11597013241374e-09,"d":"6.12E-09"},0.487893073,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2E-10,"d":"1.20E-10"},"rs148063610;rs10793624:rs148063610;rs150231142:rs148063610:rs148063610;rs150231142;rs10793624",28]
["ENSG00000175216","CKAP5",11,46764598,46867847,-1,"protein_coding",9793,"CKAP5",0.99999999753418,-0.360017002,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.8e-08,"d":"5.80E-08"},"11:47650138_AT_A:rs3972616",29]
["ENSG00000134569","LRP4",11,46878419,46940193,-1,"protein_coding",4038,"LRP4",0.10020880429216,0.314361929,0,0,4,{"v":6.68079e-07,"d":"6.68E-07"},{"v":4.55827e-32,"d":"4.56E-32"},"GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":1.9e-07,"d":"1.90E-07"},"11:47650138_AT_A;rs12790666",29]
["ENSG00000149179","C11orf49",11,46958240,47185936,1,"protein_coding",79096,"C11orf49",{"v":5.45467879227827e-07,"d":"5.45E-07"},0.564557873,0,0,1,0.000568611,0.000636697,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":3E-9,"d":"3.00E-09"},"11:47650138_AT_A",29]
["ENSG00000149182","ARFGAP2",11,47185848,47198676,-1,"protein_coding",84364,"ARFGAP2",0.562990971385505,-0.150781591,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.5E-9,"d":"1.50E-09"},"11:47650138_AT_A",29]
["ENSG00000165912","PACSIN3",11,47199076,47207994,-1,"protein_coding",29763,"PACSIN3",0.0167930476176259,-0.514938878,0,0,9,{"v":5.92561e-05,"d":"5.93E-05"},{"v":2.82949E-14,"d":"2.83E-14"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops",{"v":2.8e-09,"d":"2.80E-09"},"rs4752891;rs7124275;11:47650138_AT_A",29]
["ENSG00000134574","DDB2",11,47236493,47260767,1,"protein_coding",1643,"DDB2",0.00511790717237921,0.677015289,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4e-09,"d":"4.00E-09"},"11:47650138_AT_A",29]
["ENSG00000134575","ACP2",11,47260853,47270457,-1,"protein_coding",53,"ACP2",0.00052597665714545,-0.370782179,0,0,179,{"v":7.55603e-08,"d":"7.56E-08"},{"v":5.15985e-08,"d":"5.16E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs3972616;rs12790666;11:47650138_AT_A:rs12790666:rs3972616",29]
["ENSG00000025434","NR1H3",11,47269851,47290396,1,"protein_coding",10062,"NR1H3",0.856185983167695,0.657584133,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A:rs12790666:rs3972616",29]
["ENSG00000110514","MADD",11,47290712,47351582,1,"protein_coding",8567,"MADD",0.000901823421065546,-0.375050357,0,0,172,{"v":1.40214e-07,"d":"1.40E-07"},{"v":2.07197E-8,"d":"2.07E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.7E-10,"d":"5.70E-10"},"rs3972616;11:47650138_AT_A;11:47650138_AT_A:rs3972616",29]
["ENSG00000134571","MYBPC3",11,47352957,47374253,-1,"protein_coding",4607,"MYBPC3",{"v":1.35053975034244E-6,"d":"1.35E-06"},-0.432352402,27,14.21,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;rs3972616",29]
["ENSG00000066336","SPI1",11,47376411,47400127,-1,"protein_coding",6688,"SPI1",0.89723051716191,"NA",52,14.21,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs3972616;11:47650138_AT_A:rs12790666:rs3972616",29]
["ENSG00000165915","SLC39A13",11,47428683,47438047,1,"protein_coding",91252,"SLC39A13",0.0118520311660311,-0.332418514,35,21.7,183,{"v":4.13876E-17,"d":"4.14E-17"},{"v":1.13327e-12,"d":"1.13E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs12790666;rs3972616;rs374209699;rs7124275;rs56692100;11:47650138_AT_A:rs3972616:rs4752891",29]
["ENSG00000165916","PSMC3",11,47440320,47447993,-1,"protein_coding",5702,"PSMC3",0.979199713289554,-0.404697103,27,14.02,263,{"v":1.87235e-14,"d":"1.87E-14"},{"v":2.36421e-11,"d":"2.36E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs12790666;rs3972616;rs4752891;rs7124275;rs374209699;rs56692100",29]
["ENSG00000165917","RAPSN",11,47459308,47470730,-1,"protein_coding",5913,"RAPSN",0.0326445463388561,0.048781604,10,10.14,175,{"v":2.66002e-08,"d":"2.66E-08"},{"v":6.17155e-05,"d":"6.17E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs3972616;rs12790666;rs4752891",29]
["ENSG00000149187","CELF1",11,47487496,47587121,-1,"protein_coding",10658,"CELF1",0.998616884875254,-0.376215763,17,17.63,8,0.000370412,4.61108E-4,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;11:47650138_AT_A:rs374209699;rs7124275;rs56692100:rs7124275;rs4752891:rs12790666:rs3972616",29]
["ENSG00000213619","NDUFS3",11,47586888,47606114,1,"protein_coding",4722,"NDUFS3",0.0471370341289045,-0.012344566,8,14.52,1,{"v":9.79137e-05,"d":"9.79E-05"},0.0271439,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;11:47650138_AT_A:rs374209699;rs7124275;rs56692100:rs7124275;rs4752891:rs12790666:rs3972616",29]
["ENSG00000110536","PTPMT1",11,47586982,47595013,1,"protein_coding",114971,"PTPMT1",0.459152455272006,"NA",5,11.24,172,{"v":7.83196e-06,"d":"7.83E-06"},0.000699996,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;rs12790666;rs4752891;rs7124275;rs56692100;rs374209699;11:47650138_AT_A:rs374209699;rs56692100:rs7124275;rs4752891:rs12790666:rs3972616",29]
["ENSG00000123444","KBTBD4",11,47593749,47600567,-1,"protein_coding",55709,"KBTBD4",0.0180743639557145,-0.492620783,5,9.104,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;11:47650138_AT_A:rs3972616:rs4752891:rs12790666",29]
["ENSG00000231880","KBTBD4",11,47599277,47599823,1,"protein_coding",55709,"KBTBD4","NA",-0.492620783,4,9.104,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;11:47650138_AT_A:rs3972616:rs4752891:rs12790666",29]
["ENSG00000196666","FAM180B",11,47608198,47610746,1,"protein_coding",399888,"FAM180B",0.315838165150116,"NA",5,14.52,230,{"v":4.5199e-05,"d":"4.52E-05"},0.0158999,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;rs7124275;rs56692100;rs374209699;11:47650138_AT_A:rs3972616:rs4752891:rs12790666",29]
["ENSG00000172247","C1QTNF4",11,47611216,47616211,-1,"protein_coding",114900,"C1QTNF4",0.679081390678169,"NA",9,14.52,558,{"v":4.30565e-65,"d":"4.31E-65"},{"v":1.21395E-52,"d":"1.21E-52"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs3972616;rs12790666;rs4752891;rs7124275;rs56692100;rs374209699;11:47650138_AT_A:rs3972616:rs12790666",29]
["ENSG00000109919","MTCH2",11,47638867,47664175,-1,"protein_coding",23788,"MTCH2",0.166788403447163,0.036933631,17,25,169,{"v":7.83136e-06,"d":"7.83E-06"},0.0042687,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs12790666;11:47650138_AT_A:rs3972616:rs4752891",29]
["ENSG00000165923","AGBL2",11,47681143,47736941,-1,"protein_coding",79841,"AGBL2",{"v":6.81051045839789e-12,"d":"6.81E-12"},-0.765874431,13,7.718,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.7E-10,"d":"5.70E-10"},"11:47650138_AT_A;rs3972616;11:47650138_AT_A:rs3972616:rs4752891:rs7124275;rs4752891",29]
["ENSG00000109920","FNBP4",11,47738072,47788995,-1,"protein_coding",23360,"FNBP4",0.999993422916695,-0.713792045,19,7.718,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;11:47650138_AT_A:rs4752891:rs7124275;rs4752891",29]
["ENSG00000030066","NUP160",11,47799639,47870107,-1,"protein_coding",23279,"NUP160",0.023979152527532,-0.34569366,25,11.78,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.4e-10,"d":"6.40E-10"},"11:47650138_AT_A;11:47650138_AT_A:rs3972616:rs4752891:rs7124275;rs4752891:rs7124275",29]
["ENSG00000149177","PTPRJ",11,48002113,48189670,1,"protein_coding",5795,"PTPRJ",{"v":2.38654353395849E-5,"d":"2.39E-05"},"NA",29,15.35,1045,{"v":2.58513e-15,"d":"2.59E-15"},{"v":1.09337E-14,"d":"1.09E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.7E-10,"d":"5.70E-10"},"rs4752891;rs7124275;rs12790666;rs56692100;rs374209699;11:47650138_AT_A;rs3972616;rs4752891:11:47650138_AT_A:rs7124275;rs4752891:rs12790666",29]
["ENSG00000175619","OR4B1",11,48238344,48239314,1,"protein_coding",119765,"OR4B1",0.0109380186584993,0.304380954,6,8.853,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs7124275;rs4752891;rs56692100;rs374209699;rs56692100:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",29]
["ENSG00000172208","OR4X2",11,48266608,48267622,1,"protein_coding",119764,"OR4X2",{"v":1.10988723254503e-08,"d":"1.11E-08"},0.281681038,3,7.562,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs7124275;rs4752891;rs374209699;rs56692100:rs7124275:rs4752891:rs374209699;rs7124275:rs374209699:rs7124275;rs56692100:rs56692100:rs7124275",29]
["ENSG00000176567","OR4X1",11,48285413,48286330,1,"protein_coding",390113,"OR4X1",0.00015767458987061,0.540389506,5,23.5,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs7124275;rs4752891;rs374209699;rs56692100:rs7124275;rs4752891:rs7124275:rs7124275;rs56692100:rs4752891:rs56692100:rs374209699;rs7124275:rs374209699",29]
["ENSG00000176555","OR4S1",11,48327775,48328704,1,"protein_coding",256148,"OR4S1",4.61719061361746E-3,0.795797779,7,6.242,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs7124275;rs4752891;rs374209699;rs56692100:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",29]
["ENSG00000176547","OR4C3",11,48346472,48347507,1,"protein_coding",256144,"OR4C3",0.00874513097467769,0.097057746,3,2.329,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs7124275;rs4752891;rs374209699;rs56692100:rs374209699:rs374209699;rs7124275:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275",29]
["ENSG00000176540","OR4C5",11,48387037,48388017,-1,"protein_coding",79346,"OR4C5",0.0165676629621224,"NA",10,16.87,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs374209699;rs7124275;rs56692100;rs4752891;rs56692100:rs374209699;rs7124275:rs4752891:rs7124275;rs56692100:rs7124275:rs56692100:rs374209699",29]
["ENSG00000237388","OR4A47",11,48510269,48511332,1,"protein_coding",403253,"OR4A47",{"v":1.43390782604699E-5,"d":"1.43E-05"},0.482908751,25,13.83,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs374209699;rs7124275;rs56692100;rs4752891;rs56692100:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",29]
["ENSG00000182053","TRIM49B",11,49050504,49059579,1,"protein_coding",283116,"TRIM49B",{"v":7.55661253581996e-05,"d":"7.56E-05"},0.045340655,12,10.93,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Mesendoderm",{"v":1.7E-8,"d":"1.70E-08"},"rs374209699;rs7124275;rs56692100;rs4752891:rs4752891:rs374209699;rs56692100:rs7124275;rs56692100:rs7124275:rs56692100",29]
["ENSG00000214891","TRIM64C",11,49075266,49080664,-1,"protein_coding",646754,"TRIM64C",0.012116567412189,"NA",9,3.852,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Right_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-09,"d":"1.60E-09"},"rs374209699;rs7124275;rs56692100;rs4752891:rs4752891:rs374209699;rs56692100:rs374209699:rs374209699;rs7124275:rs7124275:rs7124275;rs56692100:rs56692100",29]
["ENSG00000086205","FOLH1",11,49168187,49230222,-1,"protein_coding",2346,"FOLH1",0.253396884638148,-0.094158315,1,5.51,890,{"v":1.38876e-14,"d":"1.39E-14"},{"v":5.1261e-17,"d":"5.13E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.6e-09,"d":"1.60E-09"},"rs374209699;rs7124275;rs56692100;rs4752891;rs4752891:rs4752891:rs374209699;rs56692100:rs374209699;rs7124275:rs374209699:rs7124275:rs7124275;rs56692100:rs56692100",29]
["ENSG00000258817","OR4C13",11,49973943,49974971,1,"protein_coding",283092,"OR4C13",{"v":8.59262892850206e-09,"d":"8.59E-09"},0.28692396,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.2E-9,"d":"1.20E-09"},"rs374209699;rs7124275;rs56692100:rs4752891:rs7124275;rs56692100:rs7124275:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",29]
["ENSG00000221954","OR4C12",11,50003009,50004071,-1,"protein_coding",283093,"OR4C12",0.23821319029955,0.040232143,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Bladder:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.6e-09,"d":"1.60E-09"},"rs374209699;rs7124275;rs56692100:rs7124275;rs4752891:rs7124275:rs4752891:rs7124275;rs56692100:rs56692100:rs374209699",29]
["ENSG00000221840","OR4A5",11,51411378,51412448,-1,"protein_coding",81318,"OR4A5","NA",0.038778801,0,0,0,"NA","NA","NA","NA","Yes","Aorta:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":5.5e-08,"d":"5.50E-08"},"rs7124275;rs4752891:rs4752891:rs374209699;rs56692100:rs7124275:rs7124275;rs56692100",29]
["ENSG00000110108","TMEM109",11,60681346,60690915,1,"protein_coding",79073,"TMEM109",0.0518905468899636,-0.925977774,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.2E-7,"d":"4.20E-07"},"rs198440:rs198470;rs198428",30]
["ENSG00000006118","TMEM132A",11,60691935,60704631,1,"protein_coding",54972,"TMEM132A",{"v":2.88925822598835e-06,"d":"2.89E-06"},"NA",0,0,3,{"v":1.86449e-05,"d":"1.86E-05"},0.0353944,"GTEx/v8/Pancreas","+","Yes","Fetal_Cortex",{"v":8.6E-11,"d":"8.60E-11"},"rs117702910;rs198440:rs198470;rs198428",30]
["ENSG00000167992","VWCE",11,61025762,61062896,-1,"protein_coding",220001,"VWCE",{"v":5.90266495568438E-13,"d":"5.90E-13"},-0.457823467,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.7e-84,"d":"2.70E-84"},"rs174564:rs61897793:rs740006",30]
["ENSG00000167986","DDB1",11,61066923,61110068,-1,"protein_coding",1642,"DDB1",0.999992284151209,-1.125296942,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1e-09,"d":"1.00E-09"},"rs546240759:rs198440:rs198470;rs198428:rs198428:rs198459",30]
["ENSG00000149476","DAK",11,61100682,61120767,1,"protein_coding",26007,"DAK",{"v":2.79479210875633e-07,"d":"2.79E-07"},-1.078555475,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1e-09,"d":"1.00E-09"},"rs546240759:rs198440:rs198470;rs198428:rs198428:rs198459",30]
["ENSG00000162144","CYB561A3",11,61116217,61129771,-1,"protein_coding",220002,"CYB561A3",0.0587317231678231,-0.713240962,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.2E-7,"d":"4.20E-07"},"rs546240759:rs198440:rs198470;rs198428",30]
["ENSG00000149483","TMEM138",11,61129473,61136981,1,"protein_coding",51524,"TMEM138",0.53112115683539,-0.907267507,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.2E-7,"d":"4.20E-07"},"rs546240759:rs198440:rs198470;rs198428",30]
["ENSG00000187049","TMEM216",11,61159159,61166335,1,"protein_coding",51259,"TMEM216",0.00201929498374557,-0.381411902,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4e-12,"d":"1.40E-12"},"rs198440:rs198470;rs198428",30]
["ENSG00000149532","CPSF7",11,61170121,61197503,-1,"protein_coding",79869,"CPSF7",0.991330175057795,-1.553287776,0,0,1,0.000191832,{"v":4.53035e-12,"d":"4.53E-12"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":5.2E-82,"d":"5.20E-82"},"rs174564;rs546240759:rs198440:rs198470;rs198428",30]
["ENSG00000256591","RP11-286N22.8",11,61196692,61253294,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.2E-7,"d":"4.20E-07"},"rs546240759:rs198440:rs198470;rs198428",30]
["ENSG00000167985","SDHAF2",11,61197514,61215001,1,"protein_coding",54949,"SDHAF2",{"v":6.97874038276147E-5,"d":"6.98E-05"},0.630341517,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.2E-7,"d":"4.20E-07"},"rs546240759:rs198440:rs198470;rs198428",30]
["ENSG00000162148","PPP1R32",11,61248592,61258403,1,"protein_coding",220004,"PPP1R32",{"v":2.68242098295629e-07,"d":"2.68E-07"},-0.32639483,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:IMR90",{"v":1e-09,"d":"1.00E-09"},"rs546240759:rs117702910:rs198440",30]
["ENSG00000204950","LRRC10B",11,61276272,61278482,1,"protein_coding",390205,"LRRC10B","NA",0.211958244,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:IMR90",{"v":9.2e-85,"d":"9.20E-85"},"rs198440:rs174564:rs61897793:rs509360:rs174532:rs117702910:rs546240759",30]
["ENSG00000011347","SYT7",11,61282785,61348620,-1,"protein_coding",9066,"SYT7",0.904578639335977,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-12,"d":"1.40E-12"},"rs546240759:rs198440:rs198470;rs198428:rs198428:rs198459",30]
["ENSG00000134780","DAGLA",11,61447905,61514473,1,"protein_coding",747,"DAGLA",0.953148342492449,-0.966158154,58,17.6,70,{"v":2.33097e-12,"d":"2.33E-12"},{"v":4.58321e-08,"d":"4.58E-08"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs198440;rs198470;rs198428;rs198459;rs546240759;rs11230796;rs2269928;rs198428:rs198440:rs198428:rs546240759:rs198459:rs174564:rs412334:rs117702910:rs174575:rs174564;rs174575:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:11:61742244_CAA_C:rs56215258:11:61742244_CAA_C;rs56215258:rs61897793:rs740006:rs174460;rs174621:rs112543847:11:61625723_CA_C;rs174460:rs174460:rs693672",30]
["ENSG00000124920","MYRF",11,61520114,61555990,1,"protein_coding",745,"MYRF",0.999847803435962,-1.659589693,59,19.93,97,{"v":1.09303E-44,"d":"1.09E-44"},{"v":4.14272e-37,"d":"4.14E-37"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Spleen:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs198440;rs198470;rs198428;rs198459;rs11230796;rs2269928;11:61537648_TG_T;rs174532;rs174564;rs61897793;rs509360;rs740006;rs412334;rs174575;rs546240759;rs174564:rs61897793:rs509360:rs174532:rs740006:rs198440:rs198470;rs198428:rs198428:rs198459:rs546240759",30]
["ENSG00000134825","TMEM258",11,61535973,61560274,-1,"protein_coding",746,"TMEM258",0.000864646359600505,0.122739186,44,19.93,94,{"v":3.8129e-13,"d":"3.81E-13"},{"v":4.06714e-09,"d":"4.07E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs11230796;rs198470;rs2269928;11:61537648_TG_T;rs174532;rs174564;rs61897793;rs509360;rs740006;rs412334;rs174575;11:61620703_CTCTT_C;rs174605;11:61625723_CA_C;rs174627;rs693672;rs2072114;rs2727263;rs174460;rs198440:rs198470;rs198428:rs198459:rs174564:rs117702910:rs174460;rs174621:rs112543847:11:61625723_CA_C;rs174460:rs174460:rs693672:rs174575:rs174564;rs174575:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:rs73487492;rs117702910:rs375103265:rs2727263:rs61897793:rs174575;11:61620703_CTCTT_C:11:61620703_CTCTT_C:rs73487492:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs174618:rs7394459:rs174621:rs7118175:rs174627:11:61625723_CA_C;rs174618:rs693672;rs174627:rs529349261:rs412334:rs174471:rs693672;rs174474;rs174477:rs174474:rs174477:rs693672;rs174477:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C",30]
["ENSG00000168496","FEN1",11,61560109,61564716,1,"protein_coding",2237,"FEN1",{"v":3.47774227503768e-05,"d":"3.48E-05"},-0.45994024,20,14.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564;rs61897793;rs740006;rs412334;rs2072114;rs2727263;rs198440:rs198470;rs198428:rs198459:rs174564:rs117702910:rs174460;rs174621:rs112543847:11:61625723_CA_C;rs174460:rs174460:rs693672:rs174575:rs174564;rs174575:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:rs73487492;rs117702910:rs375103265:rs2727263:rs61897793:rs174575;11:61620703_CTCTT_C:11:61620703_CTCTT_C:rs73487492:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs174618:rs7394459:rs174621:rs7118175:rs174627:11:61625723_CA_C;rs174605;rs174618:rs693672;rs174627:rs529349261:rs412334:rs174471:rs693672;rs174474;rs174477:rs174474:rs174477:rs693672;rs174477:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C",30]
["ENSG00000134824","FADS2",11,61560452,61634826,1,"protein_coding",9415,"FADS2",0.990052486204972,-0.476245695,187,15.66,160,{"v":3.82558e-35,"d":"3.83E-35"},{"v":2.60172e-28,"d":"2.60E-28"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564;rs61897793;rs740006;rs412334;rs2072114;rs2727263;rs117702910;rs174570;rs174575;11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C;rs139957766;rs73487492;rs375103265;11:61620703_CTCTT_C;rs174602;rs498793;rs526126;11:61625723_CA_C;rs174605;rs174618;rs7394459;rs174621;rs7118175;rs174627;rs174460;rs198440;rs2269928;rs509360;rs693672;rs174477;rs56215258;11:61537648_TG_T;rs174532;rs174471;rs198470;rs174474;rs198440:rs198470;rs198428:rs174564:rs117702910:rs174460;rs174621:rs112543847:11:61625723_CA_C;rs174460:rs174460:rs693672:rs174575:rs174564;rs174575:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:rs73487492;rs117702910:rs375103265:rs2727263:rs61897793:rs174575;11:61620703_CTCTT_C:11:61620703_CTCTT_C:rs73487492:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs174618:rs7394459:rs174621:rs7118175:rs174627:11:61625723_CA_C;rs174618:rs693672;rs174627:rs529349261:rs412334:rs174471:rs693672;rs174477:rs174474:rs174477:rs693672;rs174477:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C",30]
["ENSG00000149485","FADS1",11,61567099,61596790,-1,"protein_coding",3992,"FADS1",0.383801126989728,-0.763752724,70,15.38,195,{"v":7.61519e-47,"d":"7.62E-47"},{"v":5.32071e-39,"d":"5.32E-39"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564;rs740006;rs412334;rs2072114;rs2727263;rs117702910;rs174570;rs61897793;rs174575;11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C;11:61625723_CA_C;rs174618;rs198470;rs174532;rs174605;rs174621;rs174627;rs174460;rs693672;11:61742244_CAA_C;rs56215258;rs139957766;rs112543847;rs509360;rs73487492;11:61620703_CTCTT_C;rs174474;rs174477;rs174575:rs174564;rs174575:rs117702910:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:rs73487492;rs117702910:rs375103265:rs174564:rs2727263:rs61897793:rs174575;11:61620703_CTCTT_C:11:61620703_CTCTT_C:rs73487492:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs174618:rs7394459:rs174621:rs7118175:rs174627:11:61625723_CA_C;rs174618:11:61625723_CA_C;rs174460:rs693672;rs174627:rs174460;rs174621:rs174460:rs112543847:rs693672:rs529349261:rs412334:rs174471:rs693672;rs174477:rs174474:rs174477:rs693672;rs174477:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C",30]
["ENSG00000221968","FADS3",11,61640991,61659523,-1,"protein_coding",3995,"FADS3",0.0488722447276726,"NA",65,15.66,46,{"v":2.40861E-8,"d":"2.41E-08"},0.000283143,"GTEx/v8/Liver","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174621;rs7394459;11:61625723_CA_C;rs174618;rs7118175;rs174627;rs174605;rs174460;rs693672;rs112543847;rs529349261;rs412334;rs174471;rs174474;rs174477;rs174564;rs174575;rs2072114;rs2727263;rs56215258:11:61742244_CAA_C;rs56215258:rs174564:11:61620703_CTCTT_C:rs174575;11:61620703_CTCTT_C:rs174575:rs73487492:rs2727263:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs174618:rs7394459:rs174621:rs7118175:rs174627:11:61625723_CA_C;rs174618:11:61625723_CA_C;rs174460:rs412334:rs117702910:rs174564;rs174575:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:11:61742244_CAA_C:rs198440:rs198470;rs198428:rs174570:rs61897793:rs2736604:rs2736594",30]
["ENSG00000167994","RAB3IL1",11,61664773,61687741,-1,"protein_coding",5866,"RAB3IL1",0.000894540821499919,-0.364568465,39,15.57,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174460;rs174621;11:61625723_CA_C;rs112543847;rs693672;rs529349261;rs412334;rs174471;rs174474;rs174477;rs2736604;rs198440:rs198470;rs198428:rs198459:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C:rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575:rs7394459:11:61625723_CA_C;rs174460:rs174618:rs174621:rs693672;rs174627:rs174460;rs174621:rs174460:rs112543847:rs693672:rs529349261:rs174471:rs693672;rs174477:rs174474:rs174477:rs693672",30]
["ENSG00000167995","BEST1",11,61717293,61732987,1,"protein_coding",7439,"BEST1",{"v":4.88561552823397e-08,"d":"4.89E-08"},0.261397399,15,19.26,10,{"v":4.08457e-07,"d":"4.08E-07"},0.000730003,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Spleen:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs2736604;rs2736594;rs56215258;11:61742244_CAA_C;rs529349261:rs412334:rs174471:rs112543847:rs693672;rs174474;rs174477:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C:rs2736594:rs174564:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575:rs7394459:11:61625723_CA_C;rs174460:rs174618:rs174621:rs693672;rs174627:rs174460;rs174621:rs174460:rs693672:rs174474:rs174477:rs693672;rs174477",30]
["ENSG00000167996","FTH1",11,61727190,61735132,-1,"protein_coding",2495,"FTH1",0.918437494529701,"NA",15,19.26,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs2736594;rs56215258;11:61742244_CAA_C;rs2736594:rs56215258:11:61742244_CAA_C:rs2736604:rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575",30]
["ENSG00000269089","AP003733.1",11,61735453,61736755,1,"protein_coding","NA","NA","NA","NA",14,13.73,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs56215258;11:61742244_CAA_C;rs2736594:rs56215258:11:61742244_CAA_C:rs2736604:rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575",30]
["ENSG00000149503","INCENP",11,61891445,61920635,1,"protein_coding",3619,"INCENP",0.996086664513722,0.518652588,0,0,3,{"v":1.0766E-5,"d":"1.08E-05"},{"v":4.01029e-07,"d":"4.01E-07"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops",{"v":6.7e-86,"d":"6.70E-86"},"rs174618;11:61625723_CA_C;rs174564:rs61897793:rs509360:rs174532:rs174575:rs174564;rs174575:rs117702910:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:rs73487492;rs117702910:rs375103265:rs2727263:rs174575;11:61620703_CTCTT_C:11:61620703_CTCTT_C:rs73487492:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs174618:rs7394459:rs174621:rs7118175:rs174627:11:61625723_CA_C;rs174605;rs174618:11:61625723_CA_C;rs174460:rs693672;rs174627:rs174460;rs174621:rs174460:rs112543847",30]
["ENSG00000168515","SCGB1D1",11,61957688,61961011,1,"protein_coding",10648,"SCGB1D1",{"v":1.19495732132787e-05,"d":"1.19E-05"},0.599544717,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.7e-86,"d":"6.70E-86"},"rs7394459:11:61625723_CA_C;rs174460:rs174618:rs174621:rs693672;rs174627:rs174460;rs174621:rs174460:rs112543847:rs693672:rs529349261:rs412334:rs174471:rs693672;rs174474;rs174477:rs174474:rs174477:rs693672;rs174477:rs174575:rs174564;rs174575:rs117702910:rs2072114;rs2727263:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs2072114:rs174575;rs61897793:rs139957766:rs73487492;rs117702910:rs375103265:rs174564:rs2727263:rs61897793:rs174575;11:61620703_CTCTT_C:11:61620703_CTCTT_C:rs73487492:rs174602:rs498793:rs526126:11:61625723_CA_C:11:61625723_CA_C;rs174605:rs174605:11:61625723_CA_C;rs174618:rs7118175:rs174627:11:61625723_CA_C;rs174605;rs174618:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C",30]
["ENSG00000124939","SCGB2A1",11,61976140,61981408,1,"protein_coding",4246,"SCGB2A1",0.0564012954624431,-0.285394902,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.6e-88,"d":"9.60E-88"},"rs7394459:rs174627:rs174621:rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575:11:61625723_CA_C;rs174460:rs174618:rs693672;rs174627:rs174460;rs174621:rs174460:rs112543847:rs693672:rs529349261:rs174471:rs693672;rs174474;rs174477:rs174474:rs174477:rs693672;rs174477:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C:rs546240759:rs198440:rs198470;rs198428:rs198428:rs198459",30]
["ENSG00000124935","SCGB1D2",11,62009682,62012280,1,"protein_coding",10647,"SCGB1D2",0.0961136812474541,0.413895139,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-22,"d":"1.40E-22"},"rs2072114;rs2727263:rs174575:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs7394459:rs174627:rs174621:rs117702910:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C:rs198440:rs198470;rs198428:rs198428:rs198459:rs2736604",30]
["ENSG00000110484","SCGB2A2",11,62037627,62040628,1,"protein_coding",4250,"SCGB2A2",0.00892427737697349,0.135576389,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-22,"d":"1.40E-22"},"rs2072114;rs2727263:rs174575:11:61602496_CCTCCCTGCCTCCCCAGGGACTT_C:rs7394459:rs174627:rs174621:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C:rs198440:rs198470;rs198428:rs198428:rs198459:rs2736604",30]
["ENSG00000197745","SCGB1D4",11,62063754,62066536,-1,"protein_coding",404552,"SCGB1D4",0.00290219205998929,-0.07411136,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":9.6e-88,"d":"9.60E-88"},"rs198440:rs198470;rs198428:rs174564:rs117702910:rs2736604:rs2736594:rs56215258:11:61742244_CAA_C;rs56215258:11:61742244_CAA_C",30]
["ENSG00000149021","SCGB1A1",11,62172575,62190667,1,"protein_coding",7356,"SCGB1A1",0.00766133226097893,-0.037506253,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.9e-87,"d":"5.90E-87"},"rs174570:rs174564:rs61897793:rs174575:rs117702910:rs174621:rs7394459:11:61625723_CA_C;rs174618:rs7118175:rs174618:rs174627:11:61625723_CA_C;rs174605;rs174618:11:61625723_CA_C;rs174460",30]
["ENSG00000124942","AHNAK",11,62201016,62323707,-1,"protein_coding",79026,"AHNAK",0.344567387106657,-0.479742138,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575",30]
["ENSG00000254772","EEF1G",11,62327073,62342401,-1,"protein_coding",1937,"EEF1G",0.998058440819428,-0.553159942,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564:rs117702910:rs412334:rs2072114;rs2727263:rs174570:rs61897793:rs174575",30]
["ENSG00000255508","MIR3654",11,62327075,62359003,-1,"protein_coding",100500804,"MIR3654","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575",30]
["ENSG00000149016","TUT1",11,62342517,62359649,-1,"protein_coding",64852,"TUT1",{"v":9.985102139972e-06,"d":"9.99E-06"},-0.411888741,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":9.6e-88,"d":"9.60E-88"},"rs174564:rs412334:rs2072114;rs2727263:rs117702910:rs174570:rs61897793:rs174575",30]
["ENSG00000149480","MTA2",11,62360686,62369312,-1,"protein_coding",9219,"MTA2",0.978013018375655,0.105631729,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":9.6e-88,"d":"9.60E-88"},"rs198440:rs198470;rs198428:rs198459:rs174564:rs117702910",30]
["ENSG00000149499","EML3",11,62369690,62380237,-1,"protein_coding",256364,"EML3",0.394340909405705,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.7e-84,"d":"2.70E-84"},"rs174564:rs61897793:rs740006:rs174564;rs174575:rs73487492;rs117702910:rs2072114;rs2727263:rs174575;rs61897793:rs117702910:rs174575:rs375103265:rs2727263:rs174575;11:61620703_CTCTT_C:rs2736604",30]
["ENSG00000149489","ROM1",11,62379194,62382592,1,"protein_coding",6094,"ROM1",0.00326883045590689,"NA",0,0,1,0.000206501,{"v":1.99871e-39,"d":"2.00E-39"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":9.9e-14,"d":"9.90E-14"},"rs174471",30]
["ENSG00000149541","B3GAT3",11,62382768,62389647,-1,"protein_coding",26229,"B3GAT3",0.000286974910106167,-0.288758963,0,0,4,{"v":5.66585E-5,"d":"5.67E-05"},0.0435735,"GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":8.1e-87,"d":"8.10E-87"},"rs174564;rs174564:rs61897793:rs740006:rs174564;rs174575:rs73487492;rs117702910:rs2072114;rs2727263:rs174575;rs61897793:rs117702910:rs174575:rs375103265:rs2727263:rs174575;11:61620703_CTCTT_C:rs2736604",30]
["ENSG00000089597","GANAB",11,62392298,62414104,-1,"protein_coding",23193,"GANAB",0.99994841038629,-1.005335984,0,0,7,{"v":4.0164e-06,"d":"4.02E-06"},0.0180353,"GTEx/v8/Liver","+","No","NA",{"v":3.1e-38,"d":"3.10E-38"},"rs174575;rs61897793",30]
["ENSG00000185085","INTS5",11,62414320,62420774,-1,"protein_coding",80789,"INTS5",0.999284368233793,-0.518034449,0,0,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Promoter_anchored_loops",{"v":8.9e-10,"d":"8.90E-10"},"rs198440:rs198470;rs198428:rs198428",30]
["ENSG00000255432","RP11-831H9.11",11,62417166,62432650,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":9.6e-88,"d":"9.60E-88"},"rs198440:rs198470;rs198428:rs174564:rs117702910",30]
["ENSG00000162194","C11orf48",11,62430287,62439727,-1,"protein_coding",79081,"C11orf48",{"v":1.53758667829402E-5,"d":"1.54E-05"},0.062299998,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":9.6e-88,"d":"9.60E-88"},"rs198440:rs198470;rs198428:rs174564:rs117702910",30]
["ENSG00000214756","METTL12",11,62432781,62435968,1,"protein_coding",751071,"METTL12",0.00946026365697049,-0.808107635,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":9.6e-88,"d":"9.60E-88"},"rs198440:rs198470;rs198428:rs174564:rs117702910",30]
["ENSG00000204922","C11orf83",11,62437745,62441159,1,"protein_coding",790955,"C11orf83",0.000546458147219791,-1.075616247,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":9.6e-88,"d":"9.60E-88"},"rs198440:rs198470;rs198428:rs174564:rs117702910",30]
["ENSG00000162191","UBXN1",11,62443970,62446567,-1,"protein_coding",51035,"UBXN1",0.768417510378765,-0.657821788,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":9.6e-88,"d":"9.60E-88"},"rs174564:rs117702910",30]
["ENSG00000166682","TMPRSS5",11,113558272,113577095,-1,"protein_coding",80975,"TMPRSS5",{"v":2.57785706102948E-8,"d":"2.58E-08"},0.18379421,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.9E-23,"d":"3.90E-23"},"rs523549:rs523980:rs481843;rs523980:rs516226",31]
["ENSG00000048028","USP28",11,113668596,113746292,-1,"protein_coding",57646,"USP28",0.031657505195455,0.869552466,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.8E-126,"d":"1.80E-126"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs35120633;rs6589563:rs1263151;rs1144035:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs11600380:rs651821:rs35120633:rs180327:rs3087611:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353",31]
["ENSG00000166736","HTR3A",11,113845603,113861035,1,"protein_coding",3359,"HTR3A",{"v":1.02839422335736E-9,"d":"1.03E-09"},-0.005129549,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1e-44,"d":"1.00E-44"},"rs761166016;rs117709132;rs11216206;rs12970:rs688456;rs12721028;rs72127154:rs11216206:rs11216275:rs5072;rs473172:11:116715390_ATAT_A:rs769915248;rs374749810:rs72127154:rs35477610;rs5070;rs146811643;rs236914:rs5070;rs236914:rs769915248:rs5072;rs90192;rs473172:rs5070:rs688456;rs72127154;rs11216275;11:116903390_CT_C;rs769915248:rs5070;rs236914:rs3087611:rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763",31]
["ENSG00000109906","ZBTB16",11,113930315,114121398,1,"protein_coding",7704,"ZBTB16",0.980087305825708,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-126,"d":"1.80E-126"},"rs481843;rs523980:rs61905060:rs545108:rs516226:rs486394:rs523980:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763:rs35120633;rs6589563:rs1263151;rs1144035:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs11600380:rs651821:rs35120633:rs180327:rs3087611:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353",31]
["ENSG00000166741","NNMT",11,114128509,114184007,1,"protein_coding",4837,"NNMT",0.00427916395502723,-0.273618136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763:rs761166016;rs117709132;rs11216206;rs12970:rs35477610;rs5070;rs146811643;rs236914:rs5072;rs473172:rs545274:11:116715390_ATAT_A:rs688456;rs12721028;rs72127154:rs118138924:rs769915248;rs374749810:rs3087611:rs35477610;rs236914;rs761166016;rs12970:rs473172:rs5072;rs90192;rs473172:rs688456;rs72127154;rs11216275;rs12970:rs117709132;rs11216206:rs117709132;rs12970:rs10892078;rs11216164:rs12721040:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs12221682:rs10892019:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs651821:rs67120644:11:116588375_ATT_A:rs1263151;rs1144035:rs6589563:rs1263151:rs386757813:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs35120633:rs964184;rs11604424:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs508487;rs236911:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs236911:rs236913:rs186782888:rs236914:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs181009570:rs236913;rs236914:rs522645:rs2041967:rs7118999:rs964184:rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs5070;rs236914:rs368142965:rs688456;rs11216275:rs12366015:11:116903390_CT_C:rs141469619:rs688456;11:116903390_CT_C;rs769915248:rs12721028",31]
["ENSG00000180425","C11orf71",11,114262165,114271139,-1,"protein_coding",54494,"C11orf71",0.00842481501256066,-0.124748547,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs12221682:rs10892019:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs651821:rs67120644:11:116588375_ATT_A:rs1263151;rs1144035:rs6589563:rs1263151:rs386757813:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs35120633:rs3087611:rs964184;rs11604424:rs12721040:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs2041967:rs7118999:rs964184:rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs117709132;rs11216206;rs12970:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs236911:rs236913:rs186782888:rs236914:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs377371164",31]
["ENSG00000076053","RBM7",11,114270752,114284925,1,"protein_coding",10179,"RBM7",0.769935289328386,-0.240422903,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs12221682:rs10892019:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs651821:rs67120644:11:116588375_ATT_A:rs1263151;rs1144035:rs6589563:rs1263151:rs386757813:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs35120633:rs3087611:rs964184;rs11604424:rs12721040:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs2041967:rs7118999:rs964184:rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs117709132;rs11216206;rs12970:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs236911:rs236913:rs186782888:rs236914:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs377371164",31]
["ENSG00000255663","RP11-212D19.4",11,114271404,114314654,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs12221682:rs10892019:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs651821:rs67120644:11:116588375_ATT_A:rs1263151;rs1144035:rs6589563:rs1263151:rs386757813:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs35120633:rs3087611:rs964184;rs11604424:rs12721040:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs2041967:rs7118999:rs964184:rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs117709132;rs11216206;rs12970:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs236911:rs236913:rs186782888:rs236914:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs377371164",31]
["ENSG00000076043","REXO2",11,114310108,114321001,1,"protein_coding",25996,"REXO2",0.888428672321779,-0.470637003,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs35120633;rs6589563:rs1263151;rs1144035:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs11600380:rs651821:rs35120633:rs180327:rs3087611:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs1787701:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs61905060:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs57984552:rs1787692:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs11824135;rs61905060:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs11822160:rs12221682:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs35310854;rs2000571:rs2000571;11:116588375_ATT_A:11:116588375_ATT_A:rs6589563:rs1263151:rs386757813:rs141414463:rs2041967:rs7118999:rs964184:rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs734104:rs5095:rs2239013",31]
["ENSG00000095110","NXPE1",11,114392437,114430617,-1,"protein_coding",120400,"NXPE1",{"v":3.48609216284613e-10,"d":"3.49E-10"},0.560244834,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":3.9E-23,"d":"3.90E-23"},"rs523549:rs523980:rs481843;rs523980:rs516226",31]
["ENSG00000137634","NXPE4",11,114441313,114466484,-1,"protein_coding",54827,"NXPE4",{"v":2.74741341116275e-08,"d":"2.75E-08"},-0.225836593,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":3.9E-23,"d":"3.90E-23"},"rs523549:rs523980:rs481843;rs523980:rs516226",31]
["ENSG00000204361","NXPE2",11,114549108,114579362,1,"protein_coding",120406,"NXPE2",0.244911849376349,-0.045975215,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-56,"d":"6.50E-56"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs12221682:rs10892019:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs651821:rs67120644:11:116588375_ATT_A:rs1263151;rs1144035:rs6589563:rs1263151:rs386757813:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327",31]
["ENSG00000182985","CADM1",11,115039938,115375675,-1,"protein_coding",23705,"CADM1",0.99438640410443,-1.276282249,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1e-44,"d":"1.00E-44"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs61905060:rs545108:rs486394:rs481843:rs57984552:rs11824135;rs61905060:rs35310854:rs74792494:rs35310854;rs2000571:rs11820504:rs1787701:rs1787692:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs35310854;rs2000571:rs758044300:rs11824135:rs11828763",31]
["ENSG00000137656","BUD13",11,116618886,116643704,-1,"protein_coding",84811,"BUD13",2.29542848916745E-3,"NA",100,20.2,2,{"v":9.98962e-06,"d":"9.99E-06"},0.0476398,"GTEx/v8/Artery_Coronary","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-131,"d":"1.80E-131"},"rs1263151;rs1144035;rs35120633;rs6589563;rs651821;rs180327;rs10892019;rs11600380;rs3087611;rs964184;rs11604424;rs12721040;rs67120644;rs143811287;rs17440824;11:116638691_AAAT_A;rs1268353;rs2041967;rs7118999;rs61905060;rs761166016;rs117709132;rs11216206;rs12970:11:116715390_ATAT_A:rs12721028;rs72127154;rs11216275:rs11216275;rs769915248:rs5072;rs473172:rs11216275:rs10892078;rs11216164:rs769915248;rs374749810:rs5072;rs90192;rs473172;rs11449159;rs236911:rs34796476:rs90192;11:116999722_TA_T;rs58065809:rs2306473:rs117709132;rs12970:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs11449159:rs236914:rs90192;rs236911:rs90192;11:116999722_TA_T:rs12970:rs90192:rs508487:rs58065809:rs1263169:rs734104:rs5095:rs5130;rs734104:rs525028:11:116715390_ATAT_A;rs12721028:rs688456;rs769915248:rs525302:rs6144523:rs525028;rs35477610;rs5070;rs6144523;rs236914;11:116715350_AT_A:rs141469619:11:116715350_AT_A:rs595137:rs688456;11:116715390_ATAT_A;rs12721028;rs72127154:rs688456;rs72127154:rs5072:rs525028;11:116715350_AT_A:rs545274:rs117709132:rs35477610;rs236914:rs525028;rs236914:11:116733789_CA_C:rs11216164:rs5072;rs473172:rs35477610;rs146811643;rs236914:rs473172:rs12721040:rs5070:rs688456;rs11216275;rs12970:rs688456;11:116903390_CT_C;rs769915248:rs5070;rs236914:rs3087611:rs5070;rs236914:rs769915248:rs688456;rs11216275:rs688456;rs11449159:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs525028;rs12366015;rs236914:rs473172;rs11449159:rs386757813:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs58065809;11:116715350_AT_A:rs117709132;rs12970:rs5072;rs236911:rs118138924:rs35120633;rs6589563:rs1263151;rs1144035:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs11600380:rs651821:rs35120633:rs508487;rs236911:rs5070;rs374749810:rs688456:rs688456;11:116733789_CA_C;rs769915248:11:116715390_ATAT_A;rs141594094:rs117709132;rs11216206:rs11216206:11:116715390_ATAT_A;rs72127154:11:116927252_GATAGAT_G:rs761166016:rs688456;rs12970:rs90192;rs58065809:rs11463525:rs180327:rs964184;rs11604424:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs35477610:rs688456;rs769915248;rs374749810:rs141594094:rs374749810:rs35477610;rs12970:rs368142965:11:116903390_CT_C:rs508487;rs236911:rs236911:rs236913:rs186782888:rs181009570:rs236913;rs236914:rs522645:rs377371164:rs386757813;rs28917234:rs28917234",31]
["ENSG00000109917","ZNF259",11,116648436,116658766,-1,"protein_coding",8882,"ZNF259",0.0193034953229086,0.002394641,52,23.3,75,{"v":1.79238e-06,"d":"1.79E-06"},0.000361971,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-131,"d":"1.80E-131"},"11:116638691_AAAT_A;rs651821;rs1268353;rs1263151;rs67120644;rs2041967;rs7118999;rs3087611;rs12721040;rs11600380;rs35120633;rs964184;rs11604424;rs1144035;rs6589567;rs758044300;rs10892019;rs6589563;rs1729408;rs525302;rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs769915248;rs374749810:rs761166016;rs117709132;rs11216206;rs12970:11:116715390_ATAT_A:rs90192;rs473172;rs11449159;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs12721028;rs11216275:rs11216275;rs769915248:rs5072;rs473172:rs11216275:rs10892078;rs11216164:rs5072;rs90192;rs236911:rs34796476:rs2306473:rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:rs236914:11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs58065809:rs1263169:rs734104:rs5095:rs5130;rs734104:rs525028:11:116715390_ATAT_A;rs12721028:rs688456;rs769915248:rs525302:rs6144523:rs525028;rs35477610;rs5070;rs6144523;rs236914;11:116715350_AT_A:rs141469619:11:116715350_AT_A:rs117709132;rs12970:rs595137:rs688456;11:116715390_ATAT_A;rs12721028;rs72127154:rs688456;rs72127154:rs5072:rs525028;11:116715350_AT_A:rs545274:rs117709132:rs35477610;rs236914:rs525028;rs236914:11:116733789_CA_C:rs11216164:rs5072;rs473172:rs117709132;rs11216206:rs35477610;rs146811643;rs236914:11:116715390_ATAT_A;rs141594094:rs473172:rs3087611:rs90192:rs386757813:rs35477610:rs688456;rs769915248;rs374749810:rs12721040:rs5070:rs688456;rs761166016;rs11216275;rs12970:rs688456;rs769915248:rs688456;rs11216275:rs688456;rs11449159:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs5070;rs12366015;rs236914:rs473172;rs11449159:11:116999722_TA_T:rs90192;11:116999722_TA_T;rs58065809:rs5072;rs236911:rs118138924:rs386757813;rs28917234:rs35120633;rs6589563:rs1263151;rs1144035:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs11600380:rs651821:rs35120633:rs508487;rs236911:rs90192;11:116999722_TA_T:rs12970:rs508487:rs5070;rs374749810:rs688456:rs688456;11:116733789_CA_C;rs769915248:rs11216206:rs5070;rs236914:rs769915248:11:116715390_ATAT_A;rs72127154:11:116927252_GATAGAT_G:rs761166016:rs688456;rs12970:rs90192;rs58065809:rs11449159:rs11463525:rs180327:rs964184;rs11604424:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs141594094:rs374749810:rs35477610;rs12970:rs368142965:11:116903390_CT_C:rs508487;rs236911:rs236911:rs236913:rs186782888:rs181009570:rs236913;rs236914:rs522645:rs377371164:rs28917234",31]
["ENSG00000110243","APOA5",11,116660083,116663136,-1,"protein_coding",116519,"APOA5",{"v":1.37735073361006e-06,"d":"1.38E-06"},0.423730278,44,23.3,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-126,"d":"1.80E-126"},"rs35120633;rs11600380;rs11604424;rs651821;rs3087611;rs1263151;rs1144035;rs964184;rs7118999;rs6589567;rs6589568;rs67120644;rs2070669:rs5095:rs734104:rs525028:rs12721028:rs5130;rs734104;rs5072:rs5130:rs3087611:rs525028;rs5070:rs5130;rs5072:rs688456;rs12721028:rs117709132:rs117709132;rs11216206:rs117709132;rs11216206;rs12970:rs5072:rs5070:11:116715390_ATAT_A;rs12721028:rs35477610;rs5070;rs146811643;rs236914:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs12721028;rs11216275:rs761166016;rs117709132;rs12970:rs688456;rs11216275;rs769915248:rs769915248;rs374749810:rs5072;rs473172:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:11:116715390_ATAT_A:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs5072;rs11449159;rs236911:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;rs236914;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs5070;rs236914:rs525028;rs12366015;rs236914:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs386757813:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs2306473:rs58065809;11:116715350_AT_A:rs236914:rs117709132;rs12970:rs58065809:rs90192;11:116999722_TA_T;rs58065809:rs11463525:rs508487;rs236911:rs90192;rs236911:rs236911:rs236913:rs186782888:rs5072;rs236911:rs118138924:rs508487;rs236911:rs90192:rs90192;11:116999722_TA_T:rs12970:rs508487:rs5070;rs374749810:rs525028;rs35477610;rs6144523;11:116715350_AT_A:11:116715350_AT_A:rs688456:rs525302:rs688456;11:116715390_ATAT_A;rs72127154:rs595137:rs688456;rs12721028:rs525028;11:116733789_CA_C;rs769915248:rs525028;11:116715350_AT_A:rs545274:rs35477610;rs236914:11:116733789_CA_C:rs11216164:rs5072;rs473172:rs688456;rs72127154:11:116715390_ATAT_A;rs141594094:rs11216206:rs5070;rs236914:rs769915248:rs688456;rs761166016;rs769915248:11:116715390_ATAT_A;rs72127154:11:116927252_GATAGAT_G:rs761166016:rs688456;rs12970:rs90192;rs58065809:rs11449159:rs35120633;rs6589563:rs1263151;rs1144035:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs11600380:rs651821:rs35120633:rs180327:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs473172:rs35477610:rs688456;rs769915248;rs374749810:rs141594094:rs374749810:rs35477610;rs12970:rs368142965:11:116903390_CT_C:rs141469619:rs181009570:rs236913;rs236914:rs522645:rs377371164:rs386757813;rs28917234:rs28917234",31]
["ENSG00000110244","APOA4",11,116691419,116694022,-1,"protein_coding",337,"APOA4",{"v":3.57595118139907e-05,"d":"3.58E-05"},0.081655096,47,23.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.4E-66,"d":"3.40E-66"},"rs734104;rs1263169;rs5095;rs12721040;rs2239013;rs140231532;rs386757813;rs2070669;rs525028;rs12721028;rs5130;rs5072;rs3087611;rs5070;rs734104:rs525028:11:116715390_ATAT_A;rs12721028:rs688456;rs769915248:rs525302:11:116715390_ATAT_A:rs6144523:rs525028;rs35477610;rs6144523;rs236914;11:116715350_AT_A:rs141469619:11:116715350_AT_A:rs117709132;rs11216206;rs12970:rs595137:rs688456;11:116715390_ATAT_A;rs72127154:rs688456;rs72127154:rs35477610;rs146811643;rs236914:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs11216275:rs761166016;rs117709132;rs12970:rs688456;rs11216275;rs769915248:rs769915248;rs374749810:rs5072;rs473172:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs5072;rs11449159;rs236911:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs5070;rs236914:rs525028;rs12366015;rs236914:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs386757813:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs236914:rs58065809:rs2306473:rs90192;11:116999722_TA_T;rs58065809:rs508487:rs58065809;11:116715350_AT_A:rs90192;rs58065809:rs117709132;rs12970:rs11449159:rs11463525",31]
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["ENSG00000149591","TAGLN",11,117070037,117075498,1,"protein_coding",6876,"TAGLN",0.241537680178233,-0.645790474,57,21.8,253,{"v":3.70697E-19,"d":"3.71E-19"},{"v":7.71611E-14,"d":"7.72E-14"},"GTEx/v8/Pancreas","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-131,"d":"1.80E-131"},"rs761166016;rs117709132;rs11216206;rs12970;rs90192;rs473172;11:116999722_TA_T;rs58065809;rs508487;rs11449159;rs236911;rs2306473;11:116715350_AT_A;rs10892078;rs1263169;rs734104;rs5130;rs525028;rs5070;rs5072;rs35477610;rs6144523;rs236914;rs11216164;rs146811643;11:116984726_CA_C;rs236913;rs12970:rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs6589567:rs6589568:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs688456;rs12721028;rs72127154:rs35477610;rs236914:11:116715390_ATAT_A;rs141594094:rs595137:rs5072;rs473172:rs10892078;rs11216164:11:116715350_AT_A:rs761166016;rs12970:rs236914:11:116999722_TA_T:rs58065809:rs2306473:11:116999722_TA_T;11:116715350_AT_A:rs90192;rs236911:rs90192;rs58065809:rs10892078:rs508487:rs58065809;rs58065809:rs5072:rs525028;11:116715350_AT_A:rs545274:rs5072;rs473172:rs525302:rs117709132:11:116715390_ATAT_A:rs525028;rs236914:11:116733789_CA_C:rs11216164:rs5072;rs236911:rs118138924:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs525028;11:116715350_AT_A:rs688456:rs688456;11:116715390_ATAT_A;rs72127154:rs525028:rs688456;rs12721028:rs688456;rs72127154;rs11216275:rs688456;11:116733789_CA_C;11:116903390_CT_C;rs11216275;rs769915248:rs117709132;rs11216206:rs35477610;rs236914:rs473172:rs90192:rs386757813:rs35477610:rs688456;rs769915248;rs374749810:rs769915248;rs374749810:rs769915248:rs141594094:rs374749810:rs11216206:rs11216275:rs72127154:rs5070;rs236914:rs5070:rs688456;rs12970:rs688456;rs769915248:rs5070;rs236914:rs473172;11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs11449159:rs11463525:rs35477610;rs769915248:rs5072;rs11449159:rs12721028;rs11216275:rs11216275;rs236911:rs34796476:rs12721028;rs72127154:rs5072;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs146811643:rs12366015:rs525028;rs12366015",31]
["ENSG00000160613","PCSK7",11,117075053,117103241,-1,"protein_coding",9159,"PCSK7",0.191369613352617,"NA",76,21.8,61,{"v":1.5239e-09,"d":"1.52E-09"},{"v":3.95162E-7,"d":"3.95E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-131,"d":"1.80E-131"},"rs761166016;rs117709132;rs11216206;rs12970;rs10892078;11:116999722_TA_T;rs58065809;11:116715350_AT_A;rs90192;rs473172;rs2306473;rs508487;rs236911;rs236913;rs186782888;rs236914;rs181009570;rs522645;rs595137;rs545274;rs118138924;rs1263169:rs734104:rs5095:rs35477610;rs5070;rs146811643;rs236914:rs761166016;rs12970:rs5072;rs473172:rs688456;rs12721028;rs72127154:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs11216275;rs769915248:rs769915248;rs374749810:rs5072;rs11449159:rs12721028;rs11216275:11:116715390_ATAT_A:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs5072;rs11449159;rs236911:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs117709132;rs12970:rs146811643:rs12366015:rs5070;rs236914:rs525028;rs12366015;rs236914:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;11:116715350_AT_A:rs386757813:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs2239013:rs377371164:rs386757813;rs28917234:rs28917234:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs525028;rs35477610;rs6144523;11:116715350_AT_A:11:116715350_AT_A:rs688456:rs525302:rs688456;11:116715390_ATAT_A;rs72127154:rs595137:rs525028:rs688456;rs12721028:rs525028;rs236914:rs688456;11:116733789_CA_C;rs769915248:rs5072:rs525028;11:116715350_AT_A:rs545274:rs117709132:rs35477610;rs236914:11:116733789_CA_C:rs11216164:rs5072;rs473172:11:116715390_ATAT_A;rs141594094:rs117709132;rs11216206:rs473172:rs90192:rs35477610:rs688456;rs769915248;rs374749810:rs769915248:rs141594094:rs118138924:rs374749810:rs35477610;rs12970:rs688456",31]
["ENSG00000167257","RNF214",11,117103341,117157161,1,"protein_coding",257160,"RNF214",0.830018244677536,"NA",14,12.16,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-131,"d":"1.80E-131"},"rs117709132;rs11216206;rs12970;rs236914;rs2306473;rs181009570;rs236913;rs522645;rs377371164;rs1263169:rs734104:rs5095:rs35477610;rs5070;rs146811643;rs236914:rs761166016;rs12970:rs5072;rs473172:rs688456;rs12721028;rs72127154:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs11216275;rs769915248:rs769915248;rs374749810:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:11:116715390_ATAT_A:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs5072;rs11449159;rs236911:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs117709132;rs12970:rs146811643:rs12366015:rs5070;rs236914:rs525028;rs12366015;rs236914:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs386757813:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs2239013:rs377371164:rs386757813;rs28917234:rs28917234:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs525028;rs35477610;rs6144523;11:116715350_AT_A:11:116715350_AT_A:rs688456:rs525302:rs688456;11:116715390_ATAT_A;rs72127154:rs595137:rs525028:rs688456;rs12721028:rs525028;rs236914:rs688456;11:116733789_CA_C;rs769915248:rs5072:rs525028;11:116715350_AT_A:rs545274:rs117709132:rs35477610;rs236914:11:116733789_CA_C:rs11216164:rs5072;rs473172:11:116715390_ATAT_A;rs141594094:rs117709132;rs11216206:rs473172:rs90192:rs35477610:rs688456;rs769915248;rs374749810:rs769915248:rs141594094:rs118138924:rs374749810:rs35477610;rs761166016;rs12970:rs688456",31]
["ENSG00000186318","BACE1",11,117156402,117186975,-1,"protein_coding",23621,"BACE1",0.944278809144277,-0.919089932,3,17.44,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs377371164;rs386757813;rs28917234;rs761166016;rs117709132;rs11216206;rs12970:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs90192;rs473172;rs11449159;rs236911:rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:rs236914:11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs58065809:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs5072;rs508487;rs90192;rs236911:11:116715390_ATAT_A:rs118138924:rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs236911:rs90192;rs236911:rs236911:rs236913:rs186782888:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs377371164",31]
["ENSG00000110274","CEP164",11,117185273,117283984,1,"protein_coding",22897,"CEP164",{"v":9.66879225304467e-18,"d":"9.67E-18"},0.753351641,2,17.44,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs386757813;rs28917234;rs761166016;rs117709132;rs11216206;rs12970:rs2306473:rs90192;rs473172;rs11449159;rs236911:rs58065809;11:116715350_AT_A:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:rs236914:11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs58065809:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs5072;rs508487;rs90192;rs236911:11:116715390_ATAT_A:rs118138924:rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs236911:rs90192;rs236911:rs236911:rs236913:rs186782888:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs377371164",31]
["ENSG00000137747","TMPRSS13",11,117771358,117800174,-1,"protein_coding",84000,"TMPRSS13",{"v":6.08622571727962e-05,"d":"6.09E-05"},2.053021914,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.3e-09,"d":"1.30E-09"},"rs377371164",31]
["ENSG00000110324","IL10RA",11,117857063,117872196,1,"protein_coding",3587,"IL10RA",0.968345855815418,-0.921352137,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.9E-23,"d":"3.90E-23"},"rs523549:rs523980:rs481843;rs523980:rs516226",31]
["ENSG00000137648","TMPRSS4",11,117947753,117992605,1,"protein_coding",56649,"TMPRSS4",{"v":1.19754386539244e-08,"d":"1.20E-08"},0.384951766,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.5e-56,"d":"6.50E-56"},"rs523549:rs523980:rs481843;rs523980:rs516226:rs1787701:rs1144035;rs1787701;rs1787692:rs57984552;rs11601584:rs61905060:rs758044300;rs10892019:rs35310854;rs2000571;rs11601584:rs57984552:rs1787692:rs1144035;rs1787701:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs11824135;rs61905060:rs879858:rs1263151;rs1144035;rs1787701:rs1144035:rs11822160:rs12221682:rs10892019:rs61905067:rs11216107:rs2000571:rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs35310854;rs2000571:rs2000571;11:116588375_ATT_A:rs651821:rs67120644:11:116588375_ATT_A:rs1263151;rs1144035:rs6589563:rs1263151:rs386757813:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327",31]
["ENSG00000110344","UBE4A",11,118230300,118269926,1,"protein_coding",9354,"UBE4A",0.937619432134248,0.396074413,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.2E-31,"d":"6.20E-31"},"rs35477610;rs5070;rs146811643;rs236914:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs12721028;rs11216275:rs761166016;rs117709132;rs11216206;rs12970:rs688456;rs11216275;rs769915248:rs769915248;rs374749810:rs5072;rs473172:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:rs236914:rs90192;rs11449159;rs236911:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs2306473:rs5072;rs508487;rs236911:11:116715390_ATAT_A:rs118138924:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs58065809",31]
["ENSG00000254873","RP11-770J1.5",11,118267810,118272610,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs117709132;rs11216206;rs12970:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs236911:rs236913:rs186782888:rs236914:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs386757813;rs28917234:rs28917234:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353",31]
["ENSG00000167283","ATP5L",11,118271869,118302211,1,"protein_coding",10632,"ATP5L",0.337891181698725,-0.416063281,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-131,"d":"1.80E-131"},"rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs117709132;rs11216206;rs12970:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2306473:rs236911:rs236913:rs186782888:rs236914:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs117709132;rs12970:rs181009570:rs236913;rs236914:rs522645:rs386757813;rs28917234:rs28917234:rs35120633;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs10892019:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353",31]
["ENSG00000255384","RP11-770J1.4",11,118303836,118305921,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8E-131,"d":"1.80E-131"},"rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013",31]
["ENSG00000118058","KMT2A",11,118307205,118397539,1,"protein_coding",4297,"KMT2A",1,-1.788949198,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8E-131,"d":"1.80E-131"},"rs651821:rs1263151:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs35120633:rs964184:rs11604424:rs1263151;rs1144035:rs964184;rs11604424:rs651821;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs734104:rs5095:rs2239013",31]
["ENSG00000149582","TMEM25",11,118401756,118417995,1,"protein_coding",84866,"TMEM25",0.00042136891544107,1.146697877,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.2E-25,"d":"4.20E-25"},"rs236914:rs761166016;rs117709132;rs11216206;rs12970:rs90192;rs473172;rs11449159;rs236911:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs2306473:rs5072;rs508487;rs90192;rs236911:11:116715390_ATAT_A:rs118138924:11:116999722_TA_T;rs58065809;11:116715350_AT_A",31]
["ENSG00000136045","PWP1",12,108079509,108106944,1,"protein_coding",11137,"PWP1",{"v":1.8549631577177e-05,"d":"1.85E-05"},-0.171875533,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000110851","PRDM4",12,108126643,108155049,-1,"protein_coding",11108,"PRDM4",0.833196847904435,-0.18119585,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000075035","WSCD2",12,108523248,108644314,1,"protein_coding",9671,"WSCD2",0.494025684101003,1.171623886,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8E-5,"d":"1.80E-05"},"rs11282820",32]
["ENSG00000174600","CMKLR1",12,108681821,108733118,-1,"protein_coding",1240,"CMKLR1",0.0685269634408008,0.847161487,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000075856","SART3",12,108916357,108955176,-1,"protein_coding",9733,"SART3",0.991709384753294,-0.230330092,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000136003","ISCU",12,108956358,108963160,1,"protein_coding",23479,"ISCU",0.135947771003731,0.494530457,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000110876","SELPLG",12,109015686,109027735,-1,"protein_coding",6404,"SELPLG",0.00495442531161246,0.826234123,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000084112","SSH1",12,109176466,109251366,-1,"protein_coding",54434,"SSH1",0.987158740858356,-2.011808117,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2e-07,"d":"2.00E-07"},"rs11282820",32]
["ENSG00000110887","DAO",12,109252708,109294819,1,"protein_coding",1610,"DAO",{"v":9.26248223544675e-15,"d":"9.26E-15"},0.031721518,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2e-07,"d":"2.00E-07"},"rs11282820",32]
["ENSG00000166111","SVOP",12,109304658,109459045,-1,"protein_coding",55530,"SVOP","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8E-5,"d":"1.80E-05"},"rs11282820",32]
["ENSG00000135093","USP30",12,109460894,109525831,1,"protein_coding",84749,"USP30",0.309014179184126,-0.709413278,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8E-5,"d":"1.80E-05"},"rs11282820",32]
["ENSG00000189046","ALKBH2",12,109525996,109531436,-1,"protein_coding",121642,"ALKBH2",0.000816686414241077,-0.248281919,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000076248","UNG",12,109535379,109548797,1,"protein_coding",7374,"UNG",0.0465811527139078,-1.048065563,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000076555","ACACB",12,109554400,109706031,1,"protein_coding",32,"ACACB",{"v":5.12432725817776e-22,"d":"5.12E-22"},0.136952699,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000139445","FOXN4",12,109715784,109747025,-1,"protein_coding",121643,"FOXN4",0.133060550432118,-0.465356883,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-5,"d":"1.80E-05"},"rs11282820",32]
["ENSG00000174527","MYO1H",12,109785708,109893328,1,"protein_coding",283446,"MYO1H",{"v":2.91611360098295e-17,"d":"2.92E-17"},0.269947126,80,12.85,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4E-8,"d":"3.40E-08"},"rs11282820",32]
["ENSG00000110906","KCTD10",12,109886461,109915349,-1,"protein_coding",83892,"KCTD10",0.17266981342374,0.585872566,18,6.466,10,{"v":2.78235e-05,"d":"2.78E-05"},{"v":1.18231E-7,"d":"1.18E-07"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2E-8,"d":"2.00E-08"},"rs11282820;rs11282820:12:109958548_AT_A",32]
["ENSG00000151148","UBE3B",12,109915207,109974507,1,"protein_coding",89910,"UBE3B",0.00938770579237683,0.786225851,3,1.397,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2E-8,"d":"2.00E-08"},"rs11282820;12:109958548_AT_A;rs11282820:12:109958548_AT_A",32]
["ENSG00000139428","MMAB",12,109991542,110011679,-1,"protein_coding",326625,"MMAB",0.00387716022324201,2.918192677,5,5.585,79,{"v":5.15399e-12,"d":"5.15E-12"},{"v":2.27735e-08,"d":"2.28E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.4E-8,"d":"3.40E-08"},"rs11282820",32]
["ENSG00000110921","MVK",12,110011060,110035067,1,"protein_coding",4598,"MVK",0.0421613966473064,-0.508881997,4,5.585,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.6e-08,"d":"6.60E-08"},"rs11282820",32]
["ENSG00000139438","FAM222A",12,110152033,110208312,1,"protein_coding",84915,"FAM222A",0.400389071715135,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000111199","TRPV4",12,110220890,110271212,-1,"protein_coding",59341,"TRPV4",{"v":7.31947219105235e-06,"d":"7.32E-06"},-0.738970458,0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2E-8,"d":"2.00E-08"},"rs11282820:12:109958548_AT_A",32]
["ENSG00000139433","GLTP",12,110288748,110318293,-1,"protein_coding",51228,"GLTP",0.22708870640821,0.063857559,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000139436","GIT2",12,110367607,110434194,-1,"protein_coding",9815,"GIT2",0.970632700807013,-0.942959049,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000076513","ANKRD13A",12,110436991,110477568,1,"protein_coding",88455,"ANKRD13A",0.350624808697698,-0.732035314,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.7e-08,"d":"6.70E-08"},"rs11282820",32]
["ENSG00000196510","ANAPC7",12,110810705,110841535,-1,"protein_coding",51434,"ANAPC7",0.999257869586772,-0.621643021,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.5e-08,"d":"2.50E-08"},"rs35350651",33]
["ENSG00000111231","GPN3",12,110890289,110907073,-1,"protein_coding",51184,"GPN3",1.00471691467198E-4,-0.618749154,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":5e-10,"d":"5.00E-10"},"rs35350651",33]
["ENSG00000204856","FAM216A",12,110906169,110928190,1,"protein_coding",29902,"FAM216A",0.0011162985137716,-0.854490491,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":5e-10,"d":"5.00E-10"},"rs35350651",33]
["ENSG00000111237","VPS29",12,110928902,110939922,-1,"protein_coding",51699,"VPS29",0.934744447933042,-0.696582918,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs35350651",33]
["ENSG00000151164","RAD9B",12,110939460,110969891,1,"protein_coding",144715,"RAD9B",{"v":3.62698610369545e-05,"d":"3.63E-05"},-0.76169697,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs35350651",33]
["ENSG00000196850","PPTC7",12,110969120,111021125,-1,"protein_coding",160760,"PPTC7",0.354852283261299,-2.603403438,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs35350651",33]
["ENSG00000204852","TCTN1",12,111051832,111087235,1,"protein_coding",79600,"TCTN1",{"v":1.86861398243824e-09,"d":"1.87E-09"},-0.456703465,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-09,"d":"1.10E-09"},"rs35350651",33]
["ENSG00000186298","PPP1CC",12,111157485,111180744,-1,"protein_coding",5501,"PPP1CC",0.944905081326266,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.4e-10,"d":"6.40E-10"},"rs35350651:rs11282820",1.35625]
["ENSG00000111252","SH2B3",12,111843752,111889427,1,"protein_coding",10019,"SH2B3",0.00592218956138136,-0.243853728,3,11.21,9,{"v":1.97397E-5,"d":"1.97E-05"},{"v":3.10557e-07,"d":"3.11E-07"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":3.3E-10,"d":"3.30E-10"},"rs35350651;rs565349424",33]
["ENSG00000204842","ATXN2",12,111890018,112037480,-1,"protein_coding",6311,"ATXN2",0.999862271558356,-0.359942109,7,11.21,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.3E-10,"d":"3.30E-10"},"rs35350651;rs35350651:rs565349424",33]
["ENSG00000089234","BRAP",12,112079950,112123790,-1,"protein_coding",8315,"BRAP",0.0157033106581831,-0.900035073,3,8.201,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-10,"d":"3.30E-10"},"rs35350651;rs565349424;rs35350651:rs565349424",33]
["ENSG00000111271","ACAD10",12,112123857,112194903,1,"protein_coding",80724,"ACAD10",{"v":4.01457480802773e-20,"d":"4.01E-20"},-0.311041181,4,4.336,3,{"v":5.5102e-05,"d":"5.51E-05"},0.0044547,"GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-10,"d":"3.30E-10"},"rs565349424;rs35350651;rs35350651:rs565349424",33]
["ENSG00000257767","RP11-162P23.2",12,112191694,112229222,1,"protein_coding","NA","NA","NA","NA",2,4.336,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs35350651;rs565349424;rs35350651:rs565349424",33]
["ENSG00000111275","ALDH2",12,112204691,112247782,1,"protein_coding",217,"ALDH2",{"v":1.73245219738394E-6,"d":"1.73E-06"},"NA",2,4.336,26,{"v":4.79083E-11,"d":"4.79E-11"},{"v":3.30709e-11,"d":"3.31E-11"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-10,"d":"3.30E-10"},"rs35350651;rs565349424;rs35350651:rs565349424",33]
["ENSG00000089022","MAPKAPK5",12,112279782,112334343,1,"protein_coding",8550,"MAPKAPK5",0.0234226025504899,"NA",1,1.811,16,{"v":9.35224e-05,"d":"9.35E-05"},{"v":9.23515E-17,"d":"9.24E-17"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.3E-10,"d":"3.30E-10"},"rs35350651;rs35350651:rs565349424",33]
["ENSG00000198270","TMEM116",12,112369086,112450970,-1,"protein_coding",89894,"TMEM116",{"v":1.14999091475817e-09,"d":"1.15E-09"},-0.6208399,0,0,13,{"v":7.39446e-09,"d":"7.39E-09"},{"v":9.62641e-46,"d":"9.63E-46"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.3E-10,"d":"3.30E-10"},"rs35350651;rs565349424",33]
["ENSG00000089248","ERP29",12,112451120,112461255,1,"protein_coding",10961,"ERP29",0.470649236214131,-0.618385075,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs35350651",33]
["ENSG00000111300","NAA25",12,112464500,112546826,-1,"protein_coding",80018,"NAA25",0.999989964284881,-1.156261746,3,10.51,3,{"v":8.79199e-07,"d":"8.79E-07"},0.000286623,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2E-8,"d":"1.20E-08"},"rs35350651;rs565349424",33]
["ENSG00000135148","TRAFD1",12,112563305,112591407,1,"protein_coding",10906,"TRAFD1",{"v":1.82691525643369E-5,"d":"1.83E-05"},-1.376326544,1,6.415,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs35350651;rs35350651:rs565349424",33]
["ENSG00000173064","HECTD4",12,112597992,112819896,-1,"protein_coding",283450,"HECTD4",0.99999999999996,"NA",4,6.415,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":3.9e-08,"d":"3.90E-08"},"rs35350651",33]
["ENSG00000089009","RPL6",12,112842994,112856642,-1,"protein_coding",6128,"RPL6",0.98828827107104,0.026755082,1,0.396,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.6e-08,"d":"2.60E-08"},"rs35350651",33]
["ENSG00000179295","PTPN11",12,112856155,112947717,1,"protein_coding",5781,"PTPN11",0.999877230878678,-2.25304246,5,9.917,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1E-8,"d":"1.00E-08"},"rs35350651",33]
["ENSG00000089169","RPH3A",12,113008184,113336686,1,"protein_coding",22895,"RPH3A",0.738603478065915,0.425291504,33,8.899,0,"NA","NA","NA","NA","No","NA",{"v":3.1E-8,"d":"3.10E-08"},"rs2384049",33]
["ENSG00000089127","OAS1",12,113344582,113369990,1,"protein_coding",4938,"OAS1",0.00123924128980461,-0.362759403,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesendoderm:hESC",{"v":3.1E-8,"d":"3.10E-08"},"rs35350651:rs2384049",33]
["ENSG00000111331","OAS3",12,113376157,113411054,1,"protein_coding",4940,"OAS3",{"v":1.82237568934062e-23,"d":"1.82E-23"},1.297253453,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":3.1E-8,"d":"3.10E-08"},"rs2384049",33]
["ENSG00000111335","OAS2",12,113416200,113449528,1,"protein_coding",4939,"OAS2",{"v":1.89091809637863E-14,"d":"1.89E-14"},-0.406420629,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":3.1E-8,"d":"3.10E-08"},"rs2384049",33]
["ENSG00000111344","RASAL1",12,113536624,113574044,-1,"protein_coding",8437,"RASAL1",{"v":4.85979006124582e-08,"d":"4.86E-08"},1.586043607,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.9e-08,"d":"3.90E-08"},"rs35350651",33]
["ENSG00000089225","TBX5",12,114791736,114846247,-1,"protein_coding",6910,"TBX5",0.991878563864068,-0.562004347,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.1E-8,"d":"3.10E-08"},"rs2384049",33]
["ENSG00000089159","PXN",12,120648250,120703574,-1,"protein_coding",5829,"PXN",0.00656841085846847,-0.711885213,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4e-07,"d":"4.00E-07"},"rs11065358:rs7970695",34]
["ENSG00000089163","SIRT4",12,120740119,120751052,1,"protein_coding",23409,"SIRT4",{"v":1.80676632025049E-7,"d":"1.81E-07"},-0.347424539,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4e-07,"d":"4.00E-07"},"rs7970695:rs11065358",34]
["ENSG00000111775","COX6A1",12,120875893,120878545,1,"protein_coding",1337,"COX6A1",0.0609575623120839,0.176100304,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358:rs7970695",34]
["ENSG00000111780","AL021546.6",12,120876001,120897809,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358:rs7970695",34]
["ENSG00000170855","TRIAP1",12,120881764,120884215,-1,"protein_coding",51499,"TRIAP1",0.590216383617478,-0.444361269,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358",34]
["ENSG00000257218","GATC",12,120884241,120899389,1,"protein_coding",283459,"GATC",{"v":7.79020409773576e-05,"d":"7.79E-05"},1.064180063,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358",34]
["ENSG00000111786","SRSF9",12,120899471,120907596,-1,"protein_coding",8683,"SRSF9",0.819638672376706,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-10,"d":"5.50E-10"},"rs11065358:rs11065358;rs7970695;rs11433243",34]
["ENSG00000088986","DYNLL1",12,120907653,120936296,1,"protein_coding",8655,"DYNLL1",0.696580483081237,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-10,"d":"5.50E-10"},"rs11065358:rs11065358;rs7970695;rs11433243",34]
["ENSG00000110871","COQ5",12,120941077,120972237,-1,"protein_coding",84274,"COQ5",{"v":7.95018460631921e-05,"d":"7.95E-05"},0.02662786,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4e-07,"d":"4.00E-07"},"rs7970695:rs11065358",34]
["ENSG00000022840","RNF10",12,120971283,121015397,1,"protein_coding",9921,"RNF10",0.502963048424231,0.037115157,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4e-07,"d":"4.00E-07"},"rs7970695:rs11065358",34]
["ENSG00000167272","POP5",12,121016567,121019201,-1,"protein_coding",51367,"POP5",{"v":1.28002317887135E-5,"d":"1.28E-05"},-0.243976841,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358:rs11065358;rs7970695;rs11433243:rs7970695:rs11433243",34]
["ENSG00000157782","CABP1",12,121078355,121105127,1,"protein_coding",9478,"CABP1",0.994401234059643,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-10,"d":"5.50E-10"},"rs11065358:rs11065358;rs7970695;rs11433243",34]
["ENSG00000110917","MLEC",12,121124672,121139667,1,"protein_coding",9761,"MLEC",0.470920638317783,1.033373744,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358:rs11065358;rs7970695;rs11433243:rs7970695:rs11065358;rs7970695:rs7970695;rs11433243:rs11433243",34]
["ENSG00000175970","UNC119B",12,121148238,121161443,1,"protein_coding",84747,"UNC119B",0.677325341021738,0.550413245,0,0,5,{"v":2.45816e-05,"d":"2.46E-05"},0.000626415,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358;rs7970695;rs11433243;rs7970695:rs11065358:rs11065358;rs11433243:rs11065358;rs7970695:rs7970695;rs11433243:rs11433243",34]
["ENSG00000157837","SPPL3",12,121200313,121342174,-1,"protein_coding",121665,"SPPL3",0.907785634336426,0.151809144,0,0,33,{"v":2.59562e-07,"d":"2.60E-07"},{"v":3.87548e-20,"d":"3.88E-20"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","No","NA",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358;rs7970695;rs11433243",34]
["ENSG00000272214","AC079602.1",12,121407641,121410095,-1,"protein_coding","NA","NA","NA","NA",20,23.4,0,"NA","NA","NA","NA","No","NA",{"v":3.4e-10,"d":"3.40E-10"},"rs11065358;rs7970695;rs11433243",34]
["ENSG00000135100","HNF1A",12,121416346,121440315,1,"protein_coding",6927,"HNF1A",0.969659467322862,-0.628781489,51,23.4,0,"NA","NA","NA","NA","No","NA",{"v":3.1e-10,"d":"3.10E-10"},"rs11065358;rs7970695;rs11433243",34]
["ENSG00000157895","C12orf43",12,121440225,121454305,-1,"protein_coding",64897,"C12orf43",{"v":2.5600625299979e-07,"d":"2.56E-07"},0.963740862,28,22.3,62,{"v":5.40914e-19,"d":"5.41E-19"},{"v":4.17435e-40,"d":"4.17E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","No","NA",{"v":2.9e-10,"d":"2.90E-10"},"rs11065358;rs7970695;rs11433243",34]
["ENSG00000135114","OASL",12,121458095,121477045,-1,"protein_coding",8638,"OASL",{"v":5.07293522290638e-12,"d":"5.07E-12"},0.332934746,8,8.319,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4e-07,"d":"4.00E-07"},"rs11065358;rs7970695;rs7970695:rs11065358",34]
["ENSG00000135124","P2RX4",12,121647660,121671909,1,"protein_coding",5025,"P2RX4",{"v":2.36800653754896e-09,"d":"2.37E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":9.6e-10,"d":"9.60E-10"},"rs11065358:rs11065358;rs7970695;rs11433243:rs11433243:rs7970695",34]
["ENSG00000110931","CAMKK2",12,121675497,121736111,-1,"protein_coding",10645,"CAMKK2",0.503475917086193,0.336425978,0,0,4,2.04434E-4,0.0246551,"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":7.9e-10,"d":"7.90E-10"},"rs11065358",34]
["ENSG00000139714","MORN3",12,122089024,122110537,-1,"protein_coding",283385,"MORN3",{"v":1.82555353991208e-06,"d":"1.83E-06"},1.089669662,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-10,"d":"5.50E-10"},"rs11065358:rs11065358;rs7970695;rs11433243",34]
["ENSG00000139725","RHOF",12,122215664,122241309,-1,"protein_coding",54509,"RHOF",0.00520736033592633,-0.238094128,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-10,"d":"5.50E-10"},"rs11065358:rs11065358;rs7970695;rs11433243",34]
["ENSG00000139718","SETD1B",12,122242086,122270562,1,"protein_coding",23067,"SETD1B",0.0224563158915498,-1.50972803,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.5e-10,"d":"5.50E-10"},"rs11065358:rs11065358;rs7970695;rs11433243",34]
["ENSG00000119242","CCDC92",12,124403207,124457378,-1,"protein_coding",80212,"CCDC92",0.368849605751602,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":5.6e-09,"d":"5.60E-09"},"rs1672907",35]
["ENSG00000179195","ZNF664",12,124456392,124499986,1,"protein_coding",144348,"ZNF664",1.6267937964256E-3,-0.308462098,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":5.6e-09,"d":"5.60E-09"},"rs1672907",35]
["ENSG00000178882","FAM101A",12,124457788,124800570,1,"protein_coding",144347,"FAM101A",0.212634236356269,0.253239307,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":5.6e-09,"d":"5.60E-09"},"rs1672907",35]
["ENSG00000073060","SCARB1",12,125261402,125367214,-1,"protein_coding",949,"SCARB1",0.0772244034409674,"NA",20,8.799,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.6e-09,"d":"5.60E-09"},"rs1672907",35]
["ENSG00000150991","UBC",12,125396150,125401914,-1,"protein_coding",7316,"UBC",0.704156666525431,2.942576815,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Adult_Cortex",{"v":5.6e-09,"d":"5.60E-09"},"rs1672907",35]
["ENSG00000139364","TMEM132B",12,125671382,126146917,1,"protein_coding",114795,"TMEM132B",0.455834501099099,1.571880434,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":2.8e-06,"d":"2.80E-06"},"rs1672907",35]
["ENSG00000186009","ATP4B",13,114303119,114312501,-1,"protein_coding",496,"ATP4B",{"v":1.84084732787283e-05,"d":"1.84E-05"},-0.325434206,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.7E-8,"d":"1.70E-08"},"rs6602911",36]
["ENSG00000184497","TMEM255B",13,114462216,114514926,1,"protein_coding",348013,"TMEM255B",{"v":3.85360358148072e-10,"d":"3.85E-10"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.7E-8,"d":"1.70E-08"},"rs6602911",36]
["ENSG00000183087","GAS6",13,114523522,114567046,-1,"protein_coding",2621,"GAS6",0.333438602414211,"NA",20,8.523,19,{"v":2.0962e-12,"d":"2.10E-12"},{"v":8.39817e-08,"d":"8.40E-08"},"GTEx/v8/Liver","-","No","NA",{"v":1.7E-8,"d":"1.70E-08"},"rs6602911",36]
["ENSG00000130177","CDC16",13,115000362,115038198,1,"protein_coding",8881,"CDC16",0.952255349904704,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.7E-8,"d":"1.70E-08"},"rs6602911",36]
["ENSG00000198824","CHAMP1",13,115079988,115092796,1,"protein_coding",283489,"CHAMP1",0.985193951059278,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.7E-8,"d":"1.70E-08"},"rs6602911",36]
["ENSG00000137871","ZNF280D",15,56922379,57210769,-1,"protein_coding",54816,"ZNF280D",0.820128047448904,-0.120447238,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.5e-31,"d":"1.50E-31"},"rs28607776;rs55966152:rs55966152:rs117266250:rs28607776:rs10162642:rs35717353:rs149299515",37]
["ENSG00000140262","TCF12",15,57210821,57591479,1,"protein_coding",6938,"TCF12",0.973899934245985,-0.962372862,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.5e-31,"d":"1.50E-31"},"rs28607776;rs55966152:rs55966152:rs117266250:rs28607776:rs10162642:rs35717353:rs149299515",37]
["ENSG00000128918","ALDH1A2",15,58245622,58790065,-1,"protein_coding",8854,"ALDH1A2",0.516630055977224,1.671453522,375,17.78,62,{"v":1.74747E-9,"d":"1.75E-09"},{"v":4.07162e-05,"d":"4.07E-05"},"GTEx/v8/Liver","-","Yes","Adult_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.2e-97,"d":"9.20E-97"},"rs117266250;rs35717353;rs55966152;rs28607776;rs10162642;rs149299515;rs413458;rs1122208;rs56195705;rs117459981;rs11853431;rs12907378;rs445093;rs11071373;rs77703135;rs147468898;rs145347194;rs200743386;rs75127556;rs4775039;rs10152355;rs1601933;rs261290;rs1601935;rs8042174;rs723967;rs576650681;15:58682029_TGAA_T;rs12905732;rs34718390;rs12708454;rs12916206;rs12438999;rs75663614;rs11071380;rs55696635;rs76898656;rs13329672;rs62000866;rs11858279;rs35300429;rs402465;rs62000869;rs34727257;rs8026082;rs792902;rs515081;rs375372;rs6494005;rs261341;15:58719759_CT_C;rs8192701;rs1077835;rs488490;rs11632618;rs72740877;rs572410;rs35138338;rs8192701:rs6494005:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;15:58719759_CT_C:rs72740877:rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs413458:rs1122208:rs56195705:rs117459981:rs11853431:rs12907378:rs445093:rs11071373:rs77703135:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs12905732:rs34718390:rs12708454:15:58682029_TGAA_T;rs12916206:rs723967;rs12438999:rs75663614:rs723967;rs11071380:rs723967:rs12905732;rs55696635:rs76898656:rs76898656;rs75127556:rs13329672;rs12708454:rs723967;rs11071380:rs12905732;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs12905732;rs11858279:rs62000866:rs12438999:rs723967;rs11071380:rs35300429:rs402465:rs55696635;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs11071380:rs11858279;rs62000869:rs12916206;rs402465:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs1077835;rs261341:rs261341:rs488490:rs1077835;rs572410:rs572410:rs488490;rs572410:rs35138338",37]
["ENSG00000166035","LIPC",15,58702768,58861151,1,"protein_coding",3990,"LIPC",1.71127202456162E-4,0.201437992,113,13.62,66,{"v":2.56012e-10,"d":"2.56E-10"},{"v":1.99668E-10,"d":"2.00E-10"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Aorta:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":9.2e-97,"d":"9.20E-97"},"rs12905732;rs55696635;rs75127556;15:58682029_TGAA_T;rs723967;rs13329672;rs12708454;rs12438999;rs11071380;rs34718390;rs62000866;rs75663614;rs11858279;rs35300429;rs402465;rs62000869;rs12916206;rs77703135;rs34727257;rs8026082;rs792902;rs515081;rs375372;rs6494005;rs261341;15:58719759_CT_C;rs8192701;rs1077835;rs488490;rs11632618;rs72740877;rs572410;rs35138338;rs261290;rs1601935;rs576650681;rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs11853431:rs445093:rs12907378:rs11071373:rs77703135:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs413458:rs1122208:rs56195705:rs117459981:rs8192701:rs6494005:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;15:58719759_CT_C:rs72740877:rs1077835;rs261341:rs261341:rs488490:rs1077835;rs572410:rs572410:rs488490;rs572410:rs35138338",37]
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["ENSG00000157470","FAM81A",15,59664892,59815748,1,"protein_coding",145773,"FAM81A",0.487072320130673,-0.479273207,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.5e-31,"d":"1.50E-31"},"rs28607776;rs55966152:rs55966152:rs117266250:rs28607776:rs10162642:rs35717353:rs149299515",37]
["ENSG00000140297","GCNT3",15,59887074,59932438,1,"protein_coding",9245,"GCNT3",{"v":4.04466927083348e-09,"d":"4.04E-09"},0.663107477,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.2e-97,"d":"9.20E-97"},"rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs12905732:rs34718390:rs12708454:15:58682029_TGAA_T;rs12916206:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs261290;rs1601935:rs723967:rs12905732;rs55696635:rs76898656:rs76898656;rs75127556:rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs12905732;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs12905732;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11071380:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs12916206;rs402465:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs11853431:rs445093:rs12907378:rs11071373:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs1601935:rs8192701:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs72740877:rs1077835;rs261341:rs261341:rs488490:rs1077835;rs488490;rs572410:rs572410:rs488490;rs572410:rs35138338:rs413458:rs1122208:rs56195705:rs117459981",37]
["ENSG00000140307","GTF2A2",15,59930261,59949740,-1,"protein_coding",2958,"GTF2A2",0.386341515138839,0.898900449,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.2e-97,"d":"9.20E-97"},"rs11853431:rs445093:rs12907378:rs11071373:rs77703135:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs12905732:rs34718390:rs12708454:15:58682029_TGAA_T;rs12916206:rs723967;rs12438999:rs75663614:rs723967;rs1601933;rs11071380:rs723967:rs12905732;rs55696635:rs76898656:rs76898656;rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs12905732;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs12905732;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11071380:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs11071380:rs11858279;rs62000869:rs12916206;rs402465:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs28607776:rs10162642:rs149299515:rs413458:rs1122208:rs56195705:rs117459981",37]
["ENSG00000182718","ANXA2",15,60639333,60695082,-1,"protein_coding",302,"ANXA2",0.00984346288196249,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1e-93,"d":"1.00E-93"},"rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs413458:rs1122208:rs56195705:rs117459981:rs11853431:rs12907378:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs12905732:rs34718390:rs12708454:15:58682029_TGAA_T;rs12916206:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs261290;rs1601935:rs723967:rs12905732;rs55696635:rs76898656:rs76898656;rs75127556:rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs12905732;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs12905732;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11071380:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs12916206;rs402465:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs8192701:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs72740877:rs1077835;rs261341:rs261341:rs488490:rs1077835;rs488490;rs572410:rs572410:rs488490;rs572410:rs35138338",37]
["ENSG00000087253","LPCAT2",16,55542910,55620582,1,"protein_coding",54947,"LPCAT2",{"v":1.12519142457894e-06,"d":"1.13E-06"},1.042935368,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000159461","AMFR",16,56395364,56459450,-1,"protein_coding",267,"AMFR",0.00142575921262617,-0.148588909,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs1968493:rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000167005","NUDT21",16,56463045,56486111,-1,"protein_coding",11051,"NUDT21",0.947296445770822,-0.951045808,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000087263","OGFOD1",16,56485402,56513012,1,"protein_coding",55239,"OGFOD1",{"v":1.29448940600909E-8,"d":"1.29E-08"},1.038879494,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000102891","MT4",16,56598961,56602869,1,"protein_coding",84560,"MT4",0.0079945846958122,0.168441799,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs1968493:rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000087250","MT3",16,56622986,56625000,1,"protein_coding",4504,"MT3",0.254133469605707,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-31,"d":"1.40E-31"},"rs1968493:rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000125148","MT2A",16,56642111,56643409,1,"protein_coding",4502,"MT2A",0.0538691874978182,-0.424007583,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000169715","MT1E",16,56659387,56661024,1,"protein_coding",4493,"MT1E",0.659212996447356,-0.089953071,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000268317","AC026461.1",16,56662971,56666150,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000205364","MT1M",16,56666145,56667898,1,"protein_coding",4499,"MT1M",{"v":9.83543934507332e-05,"d":"9.84E-05"},-0.29422965,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000205362","MT1A",16,56672578,56673999,1,"protein_coding",4489,"MT1A",0.0077761859390121,0.386134236,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493",38]
["ENSG00000169688","MT1B",16,56685811,56687116,1,"protein_coding",4490,"MT1B",0.248269442186515,0.35296703,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000198417","MT1F",16,56691606,56694610,1,"protein_coding",4494,"MT1F",0.0538496988016702,-0.344970169,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000125144","MT1G",16,56700643,56701977,-1,"protein_coding",4495,"MT1G",0.00811948407601034,0.102812001,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000205358","MT1H",16,56703726,56705041,1,"protein_coding",4496,"MT1H",0.0548412149416522,-0.294410812,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000187193","MT1X",16,56716336,56718108,1,"protein_coding",4501,"MT1X",0.0496111915968201,0.296377401,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000102900","NUP93",16,56764017,56878797,1,"protein_coding",9688,"NUP93",4.86804388235231E-3,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000070915","SLC12A3",16,56899119,56949762,1,"protein_coding",6559,"SLC12A3",{"v":5.54410952233344e-18,"d":"5.54E-18"},1.058293826,3,7.404,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs1968493;rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs118146573:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000051108","HERPUD1",16,56965960,56977798,1,"protein_coding",9709,"HERPUD1",0.82104286595303,-0.272869343,8,6.618,8,{"v":7.44854e-07,"d":"7.45E-07"},{"v":9.20685e-07,"d":"9.21E-07"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695;rs247617;rs12448528;rs12923459;rs193695:rs247617:rs12448528:rs12923459:rs1968493:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000087237","CETP",16,56995762,57017757,1,"protein_coding",1071,"CETP",{"v":5.18056762742226e-12,"d":"5.18E-12"},0.043908821,65,23.5,28,{"v":2.31346E-8,"d":"2.31E-08"},{"v":7.55584e-05,"d":"7.56E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs12923459;rs247617;rs28888131;rs12720918;rs4783961;rs3816117;rs1864163;16:56997902_TTTTA_T;rs9929488;rs289713;rs118146573;rs11076176;rs289716;rs117427818;rs1800777;rs1968493:rs1864163;rs289713:rs118146573:rs3816117:rs247617:rs9929488:rs289713:rs11076176:rs289716:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000140853","NLRC5",16,57023397,57117443,1,"protein_coding",84166,"NLRC5",{"v":6.71793792873124e-05,"d":"6.72E-05"},0.253521756,6,23.5,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-31,"d":"1.40E-31"},"rs117427818;rs1800777;rs289716;rs1968493:rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000140848","CPNE2",16,57126449,57181878,1,"protein_coding",221184,"CPNE2",0.544003069972159,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":6.4e-31,"d":"6.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076176:rs289716:rs1968493",38]
["ENSG00000172775","FAM192A",16,57186378,57220028,-1,"protein_coding",80011,"FAM192A",0.944099351189242,-0.529181943,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076176:rs289716:rs1968493:rs28888131:rs12720918:rs4783961:rs1864163:16:56997902_TTTTA_T:rs1864163;rs289713;rs9929488:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000159579","RSPRY1",16,57220049,57274387,1,"protein_coding",89970,"RSPRY1",0.999778005187676,-0.337763107,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076176:rs289716:rs1968493:rs28888131:rs12720918:rs4783961:rs1864163:16:56997902_TTTTA_T:rs1864163;rs289713;rs9929488:rs117427818:rs117427818;rs1800777:rs1800777",38]
["ENSG00000102931","ARL2BP",16,57279010,57287516,1,"protein_coding",23568,"ARL2BP",0.000774155836962192,-0.164113324,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-31,"d":"1.40E-31"},"rs1968493:rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000102962","CCL22",16,57392684,57400102,1,"protein_coding",6367,"CCL22",0.279053454796883,1.694728431,0,0,0,"NA","NA","NA","NA","Yes","GM12878",{"v":1.4e-31,"d":"1.40E-31"},"rs193695:rs247617:rs12448528:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",38]
["ENSG00000006210","CX3CL1",16,57406370,57418960,1,"protein_coding",6376,"CX3CL1",0.963378216670433,0.27305282,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":8.7e-10,"d":"8.70E-10"},"rs1968493",38]
["ENSG00000102970","CCL17",16,57438679,57449974,1,"protein_coding",6361,"CCL17",0.0771247220885551,-0.1798114,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":8.7e-10,"d":"8.70E-10"},"rs1968493",38]
["ENSG00000185561","TLCD2",17,1611064,1613732,-1,"protein_coding",727910,"TLCD2","NA",-0.195217628,4,14.25,34,{"v":8.89995e-08,"d":"8.90E-08"},{"v":9.62284e-55,"d":"9.62E-55"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000167716","WDR81",17,1619817,1641893,1,"protein_coding",124997,"WDR81",{"v":1.26010739829094E-5,"d":"1.26E-05"},0.629469725,34,18.21,35,{"v":1.25192E-7,"d":"1.25E-07"},0.000382931,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000167711","SERPINF2",17,1646130,1658562,1,"protein_coding",5345,"SERPINF2",0.423433542043792,0.101796947,34,18.21,35,{"v":6.43444e-15,"d":"6.43E-15"},{"v":1.14275E-17,"d":"1.14E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Left_Ventricle","-","Yes","Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000132386","SERPINF1",17,1665253,1680868,1,"protein_coding",5176,"SERPINF1",{"v":8.28899615258178E-5,"d":"8.29E-05"},0.040746638,1,2.259,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000185924","RTN4RL1",17,1837971,1928639,-1,"protein_coding",146760,"RTN4RL1",0.787530525426807,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000108963","DPH1",17,1933404,1946724,1,"protein_coding",1801,"DPH1",{"v":2.34177044084966e-08,"d":"2.34E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000262664","OVCA2",17,1945327,1946724,1,"protein_coding",124641,"OVCA2",{"v":3.94781518236935E-5,"d":"3.95E-05"},0.571300226,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000177374","HIC1",17,1957448,1962981,1,"protein_coding",3090,"HIC1","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000070366","SMG6",17,1963133,2207065,-1,"protein_coding",23293,"SMG6",0.999935136420641,-0.496661291,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000167720","SRR",17,2206677,2228554,1,"protein_coding",63826,"SRR",0.179017047265105,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:hESC",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000167721","TSR1",17,2225797,2240801,-1,"protein_coding",55720,"TSR1",{"v":8.33290388723747E-20,"d":"8.33E-20"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000141258","SGSM2",17,2240792,2284352,1,"protein_coding",9905,"SGSM2",{"v":5.55963371668394E-8,"d":"5.56E-08"},0.410081586,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.6e-08,"d":"1.60E-08"},"rs11431553",39]
["ENSG00000070444","MNT",17,2287354,2304412,-1,"protein_coding",4335,"MNT",0.96048045983846,-0.896442606,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.1e-07,"d":"4.10E-07"},"rs11431553",39]
["ENSG00000205821","AC006435.1",17,2310279,2318731,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.1e-07,"d":"4.10E-07"},"rs11431553",39]
["ENSG00000186665","C17orf58",17,65987217,65989765,-1,"protein_coding",284018,"C17orf58",0.0821564161266073,0.225875314,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3e-07,"d":"3.00E-07"},"rs740516",40]
["ENSG00000196704","AMZ2",17,66243715,66253297,1,"protein_coding",51321,"AMZ2",{"v":1.54653236502662e-08,"d":"1.55E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000141337","ARSG",17,66255323,66418872,1,"protein_coding",22901,"ARSG",{"v":1.55401104160652e-05,"d":"1.55E-05"},-0.073146217,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000108932","SLC16A6",17,66263167,66287408,-1,"protein_coding",9120,"SLC16A6",0.205129420734742,0.544953981,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000070540","WIPI1",17,66417089,66453654,-1,"protein_coding",55062,"WIPI1",0.523500460994852,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000108946","PRKAR1A",17,66507921,66547460,1,"protein_coding",5573,"PRKAR1A",0.999223269468243,-0.526046164,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000108950","FAM20A",17,66531254,66597530,-1,"protein_coding",54757,"FAM20A",0.00250112243343209,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000269657","AC079210.1",17,66539369,66542970,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000141338","ABCA8",17,66863433,66951533,-1,"protein_coding",10351,"ABCA8",{"v":1.71937025604407e-33,"d":"1.72E-33"},-0.722805264,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000154258","ABCA9",17,66970629,67057205,-1,"protein_coding",10350,"ABCA9",{"v":1.27777342298461E-26,"d":"1.28E-26"},0.808506325,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000154262","ABCA6",17,67074843,67138029,-1,"protein_coding",23460,"ABCA6",{"v":1.83135791674863E-16,"d":"1.83E-16"},0.04887392,1,5.05,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000154263","ABCA10",17,67143355,67240987,-1,"protein_coding",10349,"ABCA10",{"v":1.20688643660446E-27,"d":"1.21E-27"},1.186945085,2,0.6,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000153822","KCNJ16",17,68049570,68131749,1,"protein_coding",3773,"KCNJ16",{"v":5.41974671317498e-06,"d":"5.42E-06"},0.221443806,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000123700","KCNJ2",17,68164814,68176189,1,"protein_coding",3759,"KCNJ2",0.820229027644725,0.661521385,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000267893","AC007461.1",17,70036164,70036872,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2e-09,"d":"3.20E-09"},"rs740516",40]
["ENSG00000206181","TCEB3B",18,44558943,44561988,-1,"protein_coding",51224,"TCEB3B",{"v":1.80367559188731E-8,"d":"1.80E-08"},-0.015254462,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.9e-11,"d":"6.90E-11"},"rs150342704:rs2000827:rs80187959:rs1787328:rs12962112",42]
["ENSG00000267228","IER3IP1",18,44661027,44702652,-1,"protein_coding",51124,"IER3IP1","NA",-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":5e-11,"d":"5.00E-11"},"rs9947678:rs150342704:rs2000827:rs498209",42]
["ENSG00000134049","IER3IP1",18,44681413,44702745,-1,"protein_coding",51124,"IER3IP1",0.0184346889412637,-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":5e-11,"d":"5.00E-11"},"rs9947678:rs150342704:rs2000827:rs498209",42]
["ENSG00000215474","SKOR2",18,44746293,44775554,-1,"protein_coding",652991,"SKOR2",0.611171343025554,-0.166850887,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5e-11,"d":"5.00E-11"},"rs9947678:rs150342704:rs2000827:rs498209:rs79204427:rs80187959:rs1787328:rs12962112",42]
["ENSG00000184828","ZBTB7C",18,45553044,45937123,-1,"protein_coding",201501,"ZBTB7C",0.907221460237709,-0.062747095,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":5.1e-33,"d":"5.10E-33"},"rs113258273:rs61124986:rs62100587:rs7228085:rs4939883:rs7244326:rs374401823:rs4939883;rs1540037:rs61124986;rs62100587:rs118043171:rs7230869:rs4939888:rs62100587;rs1540036:rs1540037:rs1540036:rs6507942:rs34627148:rs150560851:rs7505352:rs6507942;rs8093891:rs80075759:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs2000827:rs80067760:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs7232836:rs6507945;rs12965067;rs7232836;rs112748087:rs7238063:rs80175721;rs79204427:rs3892138:rs7505997:rs7238063;18:47388060_TC_T:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:18:47280133_TACACACACACAC_T:rs9951682:rs9947678:rs9951682;rs9947678:rs150342704:18:47388060_TC_T:rs188501176:rs10639158:rs498209:rs80187959:rs1787328:rs12962112:rs79204427",42]
["ENSG00000134030","CTIF",18,46065417,46389588,1,"protein_coding",9811,"CTIF",0.982754580423637,-0.933481785,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-06,"d":"3.60E-06"},"rs80075759:rs113258273",42]
["ENSG00000101665","SMAD7",18,46446223,46477081,-1,"protein_coding",4092,"SMAD7",0.975695730781462,-0.748267715,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5e-08,"d":"1.50E-08"},"rs113258273:rs9953300:rs80075759",1.7375]
["ENSG00000141627","DYM",18,46570039,46987717,-1,"protein_coding",54808,"DYM",{"v":5.18111501130597e-09,"d":"5.18E-09"},-0.135200517,3,4.83,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.7e-18,"d":"2.70E-18"},"rs80075759;rs113258273;rs113258273:18:47388060_TC_T:rs188501176:rs150342704:rs10639158:rs498209:rs80075759:rs9953300:rs80175721;rs79204427:rs2000827:rs9947678:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:rs9951682:rs80067760:rs9951682;rs9947678:rs7505997",1.7375]
["ENSG00000177576","C18orf32",18,47008028,47013622,-1,"protein_coding",497661,"C18orf32",0.18275268888643,-0.238183839,11,11.01,30,{"v":2.18482e-06,"d":"2.18E-06"},{"v":7.11808e-09,"d":"7.12E-09"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs113258273;rs73959582;rs150342704:rs498209:18:47388060_TC_T:rs80075759:rs113258273:rs12966382:rs1320700:rs62100587:rs4939883;rs1540037:rs4939883:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs2000827:rs80067760:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7505997:rs80175721;rs79204427:rs7238063;18:47388060_TC_T:rs9947678:rs6507945;rs12965067;rs7232836;rs112748087:rs7238063:rs7232836:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:18:47280133_TACACACACACAC_T:rs9951682:rs9951682;rs9947678:rs188501176:rs10639158:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80187959:rs1787328:rs12962112:rs79204427:rs80204526:rs12608026:rs61124986:rs7228085:rs7244326:rs374401823:rs61124986;rs62100587:rs118043171:rs62100587;rs1540036:rs1540037:rs1540036:rs150560851:rs7505352:rs543290276:18:47098703_TAAAA_T:rs77960347;rs80204526:rs77960347:rs4121823",42]
["ENSG00000215472","RPL17-C18orf32",18,47008051,47017956,-1,"protein_coding",100526842,"RPL17-C18orf32",0.605942171595584,-0.340213428,11,11.01,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs113258273;rs150342704:rs498209:18:47388060_TC_T:rs80075759:rs113258273:rs12966382:rs1320700:rs62100587:rs4939883;rs1540037:rs4939883:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs2000827:rs80067760:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7505997:rs80175721;rs79204427:rs7238063;18:47388060_TC_T:rs9947678:rs6507945;rs12965067;rs7232836;rs112748087:rs7238063:rs7232836:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:18:47280133_TACACACACACAC_T:rs9951682:rs9951682;rs9947678:rs188501176:rs10639158:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80187959:rs1787328:rs12962112:rs79204427:rs80204526:rs12608026:rs61124986:rs7228085:rs7244326:rs374401823:rs61124986;rs62100587:rs118043171:rs62100587;rs1540036:rs1540037:rs1540036:rs150560851:rs7505352:rs543290276:18:47098703_TAAAA_T:rs77960347;rs80204526:rs77960347:rs4121823",42]
["ENSG00000265681","RPL17",18,47014851,47018906,-1,"protein_coding",6139,"RPL17",0.494059426420399,0.186983574,10,11.01,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs113258273;rs150342704:rs498209:18:47388060_TC_T:rs80075759:rs113258273:rs12966382:rs1320700:rs62100587:rs4939883;rs1540037:rs4939883:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs2000827:rs80067760:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7505997:rs80175721;rs79204427:rs7238063;18:47388060_TC_T:rs9947678:rs6507945;rs12965067;rs7232836;rs112748087:rs7238063:rs7232836:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:18:47280133_TACACACACACAC_T:rs9951682:rs9951682;rs9947678:rs188501176:rs10639158:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80187959:rs1787328:rs12962112:rs79204427:rs80204526:rs12608026:rs61124986:rs7228085:rs7244326:rs374401823:rs61124986;rs62100587:rs118043171:rs62100587;rs1540036:rs1540037:rs1540036:rs150560851:rs7505352:rs543290276:18:47098703_TAAAA_T:rs77960347;rs80204526:rs77960347:rs4121823",42]
["ENSG00000101670","LIPG",18,47087069,47119272,1,"protein_coding",9388,"LIPG",{"v":8.35570265503166e-05,"d":"8.36E-05"},-0.057562727,48,24.1,11,{"v":6.52812e-06,"d":"6.53E-06"},0.00061259,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs1320700;rs12966382;rs543290276;18:47098703_TAAAA_T;rs77960347;rs80204526;rs12608026;rs4121823;rs28873777;rs1105654;rs10853582;rs150342704:rs498209:rs2000827:18:47388060_TC_T:rs113258273:rs34627148:rs6507942:rs80075759:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs62100587:rs4939883;rs1540037:rs4939883:rs7230869:rs4939888:rs80067760:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7505997:rs80175721;rs79204427:rs7238063;18:47388060_TC_T:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs7232836:rs188501176:rs10639158:rs6507945;rs12965067;rs7232836;rs112748087:rs7238063:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:18:47280133_TACACACACACAC_T:rs9951682:rs9947678:rs9951682;rs9947678",42]
["ENSG00000167315","ACAA2",18,47309869,47340330,-1,"protein_coding",10449,"ACAA2","NA","NA",26,16.22,14,{"v":3.29326e-08,"d":"3.29E-08"},{"v":6.07479e-14,"d":"6.07E-14"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs80075759;rs2000827;rs150342704;18:47388060_TC_T;rs188501176;rs10639158;rs498209;rs1787328;rs113258273:rs1320700:rs543290276:18:47098703_TAAAA_T:rs150342704:rs498209:rs12966382:rs34627148:rs6507942:rs80075759:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs80175721;rs79204427:rs2000827:18:47388060_TC_T:rs9947678:rs80204526:rs12608026:rs77960347;rs80204526:rs77960347:rs4121823:rs61124986:rs62100587:rs7228085:rs4939883:rs7244326:rs374401823:rs4939883;rs1540037:rs61124986;rs62100587:rs118043171:rs7230869:rs4939888:rs62100587;rs1540036:rs1540037:rs1540036:rs150560851:rs7505352:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80067760:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs7232836:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:rs9951682:rs9951682;rs9947678:rs7505997",42]
["ENSG00000266997","RP11-886H22.1",18,47322163,47363993,-1,"protein_coding","NA","NA","NA","NA",28,10.54,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs150342704;18:47388060_TC_T;rs188501176;rs10639158;rs498209;rs80075759;rs80175721;rs79204427;rs113258273:rs80204526:rs12608026:rs1320700:18:47388060_TC_T:rs188501176:rs150342704:rs10639158:rs498209:rs80075759:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:rs9951682:rs80067760:rs9947678:rs9951682;rs9947678:rs7505997:rs80175721;rs79204427:rs2000827:rs12966382:rs543290276:18:47098703_TAAAA_T:rs77960347;rs80204526:rs77960347:rs4121823:rs28873777:rs1105654;rs10853582:rs10853582:rs28666039:rs1016563:rs1105654:rs7229377:rs34802337:rs11663245:rs73959582:rs35311766:rs7235080:rs61124986:rs11662059:rs7230869:rs4939883:rs7229658:rs62100587:rs7228085:rs7244326:rs374401823:rs4939883;rs1540037:rs61124986;rs62100587:rs118043171:rs4939888:rs62100587;rs1540036:rs1540037:rs1540036:rs6507942:rs34627148:rs150560851:rs7505352:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs7232836:rs6507945;rs12965067;rs7232836;rs112748087:rs7238063:rs3892138:rs7238063",42]
["ENSG00000167306","MYO5B",18,47349183,47721463,-1,"protein_coding",4645,"MYO5B",{"v":5.4231747689238e-10,"d":"5.42E-10"},0.470845589,171,18.42,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.5e-45,"d":"7.50E-45"},"rs498209;18:47388060_TC_T;rs150342704;rs80075759;rs80175721;rs79204427;rs2000827;rs9947678;rs80187959;rs1787328;rs12962112;rs113258273:rs12966382:rs1320700:rs80204526:rs12608026:rs9947678:rs150342704:rs2000827:rs498209:rs79204427:rs543290276:18:47098703_TAAAA_T:rs77960347;rs80204526:rs77960347:rs4121823:rs80187959:rs1787328:rs12962112:rs80075759:rs80175721;rs79204427:18:47388060_TC_T:rs188501176:rs10639158:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9951682;rs9947678:rs9951682:rs80067760:rs9951682;rs9947678:rs7505997",42]
["ENSG00000172361","CCDC11",18,47753563,47792892,-1,"protein_coding",220136,"CCDC11",{"v":1.5987996365213e-13,"d":"1.60E-13"},-0.596742517,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.6e-38,"d":"9.60E-38"},"rs113258273:rs12966382:rs1320700:rs498209:18:47388060_TC_T:rs150342704:rs80075759:rs62100587:rs4939883;rs1540037:rs4939883:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs7238063;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs2000827:rs79204427:rs80204526:rs12608026:rs80175721;rs79204427:rs9947678:rs80187959:rs1787328:rs12962112",42]
["ENSG00000154832","CXXC1",18,47808713,47814674,-1,"protein_coding",30827,"CXXC1",0.99786210530366,-0.476982834,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.5E-10,"d":"1.50E-10"},"rs150342704",42]
["ENSG00000154839","SKA1",18,47901365,47920543,1,"protein_coding",220134,"SKA1",{"v":1.32265949651803E-6,"d":"1.32E-06"},0.423231094,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.6e-38,"d":"9.60E-38"},"rs113258273:rs12966382:rs1320700:rs80204526:rs12608026:rs79204427:rs80175721;rs79204427:rs150342704:rs2000827:rs80187959:rs1787328:rs12962112:rs9947678:rs498209",42]
["ENSG00000130812","ANGPTL6",19,10203014,10213472,-1,"protein_coding",83854,"ANGPTL6",{"v":2.76981473339532E-8,"d":"2.77E-08"},-0.292124052,0,0,1,1.90516E-4,0.0147866,"GTEx/v8/Adipose_Subcutaneous","-","No","NA",{"v":5.1E-10,"d":"5.10E-10"},"rs73015030",43]
["ENSG00000105364","MRPL4",19,10362577,10370721,1,"protein_coding",51073,"MRPL4",{"v":1.13185886619774E-7,"d":"1.13E-07"},0.262339703,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.4e-07,"d":"3.40E-07"},"rs17850995",43]
["ENSG00000105371","ICAM4",19,10397643,10399198,1,"protein_coding",3386,"ICAM4",{"v":1.53444721877808e-05,"d":"1.53E-05"},-0.287199811,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs17850995:rs140493437",43]
["ENSG00000079999","KEAP1",19,10596796,10614417,-1,"protein_coding",9817,"KEAP1",0.251629057539983,-0.049345802,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs140493437:rs17850995",43]
["ENSG00000180739","S1PR5",19,10623623,10628607,-1,"protein_coding",53637,"S1PR5",0.0574132950803294,-0.598100848,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.4e-07,"d":"3.40E-07"},"rs17850995",43]
["ENSG00000130734","ATG4D",19,10654571,10664094,1,"protein_coding",84971,"ATG4D",0.000323903626106917,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-07,"d":"3.40E-07"},"rs17850995",43]
["ENSG00000129347","KRI1",19,10663761,10676713,-1,"protein_coding",65095,"KRI1",{"v":8.4034020734588E-9,"d":"8.40E-09"},-0.684287675,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-07,"d":"3.40E-07"},"rs17850995",43]
["ENSG00000129355","CDKN2D",19,10677138,10679735,-1,"protein_coding",1032,"CDKN2D",0.147286959437682,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-07,"d":"3.40E-07"},"rs17850995",43]
["ENSG00000129354","AP1M2",19,10683347,10697991,-1,"protein_coding",10053,"AP1M2",0.00134595247967371,-0.043748277,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.4e-07,"d":"3.40E-07"},"rs17850995",43]
["ENSG00000129353","SLC44A2",19,10713133,10755235,1,"protein_coding",57153,"SLC44A2",0.0414645881648824,-0.378860929,1,0.101,5,{"v":2.77111E-5,"d":"2.77E-05"},0.000289454,"GTEx/v8/Artery_Tibial","+","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4.5e-27,"d":"4.50E-27"},"rs17850995;rs142158911;rs59716766",43]
["ENSG00000226104","AC011475.1",19,10751715,10752093,1,"protein_coding","NA","NA","NA","NA",1,0.101,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.3e-09,"d":"1.30E-09"},"rs17850995;rs17850995:rs140493437:rs56121005",43]
["ENSG00000129351","ILF3",19,10764937,10803093,1,"protein_coding",3609,"ILF3",0.999996830604967,-0.897292942,2,6.331,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":7.2E-9,"d":"7.20E-09"},"rs17850995",43]
["ENSG00000213339","QTRT1",19,10812106,10824113,1,"protein_coding",81890,"QTRT1",0.000223249642879381,-0.342791499,1,6.331,0,"NA","NA","NA","NA","No","NA",{"v":4.8e-07,"d":"4.80E-07"},"rs17850995",43]
["ENSG00000079805","DNM2",19,10828755,10944164,1,"protein_coding",1785,"DNM2",0.999968599089655,-0.475523782,19,10.77,13,{"v":4.06798e-06,"d":"4.07E-06"},{"v":5.39957e-09,"d":"5.40E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","No","NA",{"v":3.3E-10,"d":"3.30E-10"},"rs140493437;rs17850995",43]
["ENSG00000099203","TMED1",19,10943114,10946994,-1,"protein_coding",11018,"TMED1",0.000162416907640562,-0.379917355,10,10.77,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":3.3E-10,"d":"3.30E-10"},"rs17850995;rs140493437;rs17850995:rs56121005",43]
["ENSG00000214212","C19orf38",19,10947251,10980466,1,"protein_coding",255809,"C19orf38","NA",0.100777924,11,10.77,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":3.3E-10,"d":"3.30E-10"},"rs17850995;rs140493437;rs17850995:rs56121005",43]
["ENSG00000142453","CARM1",19,10982189,11033453,1,"protein_coding",10498,"CARM1",0.999357708272541,"NA",2,0.761,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-47,"d":"3.20E-47"},"rs17850995;rs17850995:rs140493437:rs59716766:rs142158911;rs59716766:rs142158911",43]
["ENSG00000130733","YIPF2",19,11033444,11039357,-1,"protein_coding",78992,"YIPF2",1.09917458451604E-3,"NA",1,0.761,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-47,"d":"3.20E-47"},"rs17850995;rs56048141:rs56121005:rs17850995:rs59716766:rs142158911;rs59716766:rs142158911",43]
["ENSG00000142444","C19orf52",19,11039409,11044211,1,"protein_coding",90580,"C19orf52",0.00198991933916563,-0.096033732,1,0.761,8,{"v":7.92387e-07,"d":"7.92E-07"},0.000675759,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-47,"d":"3.20E-47"},"rs17850995;rs140493437;rs56048141:rs56121005:rs17850995:rs59716766:rs142158911;rs59716766:rs142158911",43]
["ENSG00000127616","SMARCA4",19,11071598,11176071,1,"protein_coding",6597,"SMARCA4",0.999999997611829,"NA",2,3.729,6,{"v":5.35792e-06,"d":"5.36E-06"},0.000589482,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex",{"v":4.8E-22,"d":"4.80E-22"},"rs59716766;rs140493437;rs56048141:rs56121005",43]
["ENSG00000130164","LDLR",19,11200038,11244492,1,"protein_coding",3949,"LDLR",{"v":2.59266073718312e-16,"d":"2.59E-16"},0.415051182,82,13.85,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.2e-47,"d":"3.20E-47"},"rs142158911;rs59716766;rs8102912;rs6511721;rs73015030;rs576249617;rs5742911;rs201091555;rs56121005:rs17850995",43]
["ENSG00000161888","SPC24",19,11242196,11266484,-1,"protein_coding",147841,"SPC24",0.00627554442927794,3.9978869,24,8.935,8,{"v":3.49775e-08,"d":"3.50E-08"},{"v":8.81193e-14,"d":"8.81E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","No","NA",{"v":6.6E-17,"d":"6.60E-17"},"rs576249617;rs5742911;rs201091555;rs79668907;rs746442994;rs56237989",43]
["ENSG00000197256","KANK2",19,11274943,11308467,-1,"protein_coding",25959,"KANK2",0.981511998562845,1.108914572,16,8.935,2,1.1835E-4,{"v":7.22586e-11,"d":"7.23E-11"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":4.5e-15,"d":"4.50E-15"},"rs746442994;rs56237989;rs146576912;rs111279811;rs56048141",43]
["ENSG00000130158","DOCK6",19,11309971,11373157,-1,"protein_coding",57572,"DOCK6",{"v":2.83089712599404e-19,"d":"2.83E-19"},"NA",41,23.1,34,{"v":1.10227E-6,"d":"1.10E-06"},{"v":2.69192e-05,"d":"2.69E-05"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","No","NA",{"v":1e-15,"d":"1.00E-15"},"rs56048141;rs56322906;rs201019550;rs72996217",43]
["ENSG00000130173","C19orf80",19,11348178,11352619,1,"protein_coding",55908,"C19orf80",{"v":2.61107498638975e-06,"d":"2.61E-06"},-0.019228124,8,23.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-15,"d":"1.00E-15"},"rs56322906;rs72996217;rs72996217:rs36022659",43]
["ENSG00000130167","TSPAN16",19,11406824,11437672,1,"protein_coding",26526,"TSPAN16",2.52237775125353E-4,0.747581914,8,10.45,0,"NA","NA","NA","NA","No","NA",{"v":4.8E-9,"d":"4.80E-09"},"rs36022659;rs56121005",43]
["ENSG00000105518","TMEM205",19,11453452,11457194,-1,"protein_coding",374882,"TMEM205",0.394574027164483,-0.471673866,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":1.6E-46,"d":"1.60E-46"},"rs142158911:rs8102912",43]
["ENSG00000173928","SWSAP1",19,11485361,11487627,1,"protein_coding",126074,"SWSAP1",0.000134670403718243,-0.594213988,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2e-47,"d":"3.20E-47"},"rs17850995:rs142158911:rs59716766:rs576249617:rs5742911:rs79668907:rs746442994:rs746442994;rs56237989:rs56048141:rs72996217:rs36022659:rs56121005",43]
["ENSG00000187266","EPOR",19,11488236,11495018,-1,"protein_coding",2057,"EPOR",0.058450671852552,-0.617491308,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005:rs36022659",43]
["ENSG00000205517","RGL3",19,11495017,11530018,-1,"protein_coding",57139,"RGL3",{"v":4.36378939273708E-21,"d":"4.36E-21"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.6e-10,"d":"8.60E-10"},"rs56048141:rs56121005:rs746442994;rs56237989:rs746442994",43]
["ENSG00000130175","PRKCSH",19,11546109,11561783,1,"protein_coding",5589,"PRKCSH",0.140789247885124,-0.138498039,0,0,1,1.33552E-4,{"v":3.79207e-08,"d":"3.79E-08"},"GTEx/v8/Adipose_Visceral_Omentum","-","No","NA",{"v":4.5e-27,"d":"4.50E-27"},"rs59716766",43]
["ENSG00000196361","ELAVL3",19,11562141,11591861,-1,"protein_coding",1995,"ELAVL3",0.822602583621291,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.6E-10,"d":"3.60E-10"},"rs72996217:rs36022659",43]
["ENSG00000267477","CTC-398G3.6",19,11577055,11616513,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.6E-17,"d":"6.60E-17"},"rs5742911:rs201091555",43]
["ENSG00000161914","ZNF653",19,11594242,11616738,-1,"protein_coding",115950,"ZNF653",0.142112312658903,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.6E-17,"d":"6.60E-17"},"rs5742911:rs201091555",43]
["ENSG00000130159","ECSIT",19,11616731,11639989,-1,"protein_coding",51295,"ECSIT",0.0156465744672347,0.207619557,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000130176","CNN1",19,11649532,11661138,1,"protein_coding",1264,"CNN1",0.861520643189048,0.484495763,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":2e-09,"d":"2.00E-09"},"rs746442994:rs56237989:rs746442994;rs56237989:rs56121005",43]
["ENSG00000130165","ELOF1",19,11661962,11670051,-1,"protein_coding",84337,"ELOF1",0.403135808004397,0.065704825,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.7e-09,"d":"1.70E-09"},"rs56121005:rs746442994;rs56237989:rs746442994",43]
["ENSG00000198551","ZNF627",19,11670189,11729950,1,"protein_coding",199692,"ZNF627",0.00564414625423386,0.583732004,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.7e-09,"d":"1.70E-09"},"rs56121005:rs746442994;rs56237989:rs746442994",43]
["ENSG00000102575","ACP5",19,11685475,11689823,-1,"protein_coding",54,"ACP5",0.123568347500175,-0.16646465,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-47,"d":"3.20E-47"},"rs142158911:rs59716766:rs746442994;rs56237989:rs746442994:rs56048141:rs72996217:rs36022659:rs56121005",43]
["ENSG00000197044","ZNF441",19,11877815,11894893,1,"protein_coding",126068,"ZNF441",0.0276670958531812,0.24896725,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2e-09,"d":"2.00E-09"},"rs746442994:rs56237989:rs746442994;rs56237989",43]
["ENSG00000177599","ZNF491",19,11908482,11920437,1,"protein_coding",126069,"ZNF491",{"v":5.1306652954028E-7,"d":"5.13E-07"},-0.126939715,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000171291","ZNF439",19,11959541,11994565,1,"protein_coding",90594,"ZNF439",{"v":3.21400432787086E-8,"d":"3.21E-08"},0.642917155,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000198429","ZNF69",19,11998599,12025144,1,"protein_coding",7620,"ZNF69",{"v":7.35111939274279e-05,"d":"7.35E-05"},-0.549690848,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.6e-10,"d":"8.60E-10"},"rs56121005:rs746442994;rs56237989:rs746442994:rs56048141",43]
["ENSG00000196757","ZNF700",19,12035883,12061588,1,"protein_coding",90592,"ZNF700",{"v":4.39166088843519E-11,"d":"4.39E-11"},0.364854347,0,0,3,{"v":4.47579e-05,"d":"4.48E-05"},3.03929E-3,"GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.9e-09,"d":"2.90E-09"},"rs56322906;rs56121005",43]
["ENSG00000197054","ZNF763",19,12035890,12091196,1,"protein_coding",284390,"ZNF763",0.000236872840014969,2.327700828,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000267179","ZNF763",19,12035890,12090105,1,"protein_coding",284390,"ZNF763","NA",2.327700828,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000132010","ZNF20",19,12203658,12251222,-1,"protein_coding",7568,"ZNF20",0.0235723668010903,-0.869285434,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000213297","ZNF625-ZNF20",19,12242932,12267546,-1,"protein_coding",100529855,"ZNF625-ZNF20","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000257591","ZNF625",19,12251032,12267546,-1,"protein_coding",90589,"ZNF625",0.000825561501317101,-0.035089358,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000132026","RTBDN",19,12936292,12946242,-1,"protein_coding",83546,"RTBDN",{"v":3.27850963623921e-07,"d":"3.28E-07"},0.068260512,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000105613","MAST1",19,12944765,12985765,1,"protein_coding",22983,"MAST1",0.999999024385856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.8E-9,"d":"4.80E-09"},"rs56121005",43]
["ENSG00000141979","CTD-3222D19.2",19,16589878,16739015,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015",44]
["ENSG00000105085","MED26",19,16685718,16739873,-1,"protein_coding",9441,"MED26",0.948549941884627,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015",44]
["ENSG00000105642","KCNN1",19,18062102,18110889,1,"protein_coding",3780,"KCNN1",0.931699633359926,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3e-40,"d":"3.00E-40"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626",44]
["ENSG00000254858","MPV17L2",19,18303992,18307758,1,"protein_coding",84769,"MPV17L2",{"v":1.67296107198305e-07,"d":"1.67E-07"},0.464900432,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs143729015",44]
["ENSG00000105650","PDE4C",19,18318771,18366229,-1,"protein_coding",5143,"PDE4C",{"v":4.88574724786651e-05,"d":"4.89E-05"},0.288881628,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.3e-06,"d":"8.30E-06"},"rs143729015",44]
["ENSG00000130511","SSBP4",19,18529674,18545372,1,"protein_coding",170463,"SSBP4",0.96165888216155,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.2e-07,"d":"1.20E-07"},"rs143729015",44]
["ENSG00000105656","ELL",19,18553473,18632937,-1,"protein_coding",8178,"ELL",0.940941238331597,-0.635599911,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015",44]
["ENSG00000105701","FKBP8",19,18642561,18654887,-1,"protein_coding",23770,"FKBP8",0.9787380986207,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs143729015",44]
["ENSG00000221983","UBA52",19,18682540,18688360,1,"protein_coding",7311,"UBA52",0.4468000697986,1.709183735,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015:rs73001020;rs143729015",44]
["ENSG00000006016","CRLF1",19,18683030,18718551,-1,"protein_coding",9244,"CRLF1",0.026855594173361,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015:rs73001020;rs143729015",44]
["ENSG00000006015","C19orf60",19,18699495,18703146,1,"protein_coding",55049,"C19orf60",0.249879077699029,0.549025716,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015:rs73001020;rs143729015",44]
["ENSG00000105696","TMEM59L",19,18718240,18731849,1,"protein_coding",25789,"TMEM59L",0.0151007864967939,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":4.9E-9,"d":"4.90E-09"},"rs143729015:rs73001020;rs143729015",44]
["ENSG00000105662","CRTC1",19,18794487,18893004,1,"protein_coding",23373,"CRTC1",0.980548236291021,-2.587605964,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs143729015",44]
["ENSG00000223802","CERS1",19,18979361,19007536,-1,"protein_coding",10715,"CERS1",0.0454570437212016,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-38,"d":"8.80E-38"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs187429064:rs2285626;19:19510831_AT_A;rs17216693",44]
["ENSG00000130283","GDF1",19,18979361,19006905,-1,"protein_coding",2657,"GDF1",0.544923744446604,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-38,"d":"8.80E-38"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs187429064:rs2285626;19:19510831_AT_A;rs17216693",44]
["ENSG00000268193","AC002985.3",19,19017822,19045206,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.2e-42,"d":"8.20E-42"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000064607","SUGP2",19,19101697,19144832,-1,"protein_coding",10147,"SUGP2",0.999366871236062,0.523631183,5,6.776,20,{"v":6.38872E-7,"d":"6.39E-07"},{"v":4.0018e-05,"d":"4.00E-05"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.6e-46,"d":"8.60E-46"},"rs143729015;rs73001020;rs113954889;rs143729015:rs113954889:rs8100140:rs11882123:rs58542926:rs2285626:19:19617705_CTTTAA_C:rs187429064:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs113954889;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C",44]
["ENSG00000105676","ARMC6",19,19144384,19170563,1,"protein_coding",93436,"ARMC6",{"v":7.24407726209859e-07,"d":"7.24E-07"},"NA",1,0.21,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.6e-46,"d":"8.60E-46"},"rs143729015;rs143729015:rs113954889:rs8100140:rs11882123:rs58542926:rs2285626:19:19617705_CTTTAA_C:rs187429064:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs113954889;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C",44]
["ENSG00000181035","SLC25A42",19,19174808,19223697,1,"protein_coding",284439,"SLC25A42",0.208308450498004,-0.880389707,1,0.194,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.8e-12,"d":"2.80E-12"},"rs143729015;rs143729015:rs113954889;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:rs113954889",44]
["ENSG00000064545","TMEM161A",19,19229978,19249322,-1,"protein_coding",54929,"TMEM161A",{"v":2.04658505555468e-06,"d":"2.05E-06"},-0.270254201,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1E-41,"d":"1.10E-41"},"rs143729015:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs2285626:rs187429064:rs58542926:19:19617705_CTTTAA_C",44]
["ENSG00000064489","MEF2BNB-MEF2B",19,19256376,19302967,-1,"protein_coding",4207,"MEF2BNB-MEF2B",0.247287511423171,-0.149548186,56,12.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":8.2e-42,"d":"8.20E-42"},"rs113954889;rs28672836;19:19260892_CAAAAAAAAA_C;rs73001020:rs2285626;19:19510831_AT_A;rs17216693:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs187429064:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000213999","MEF2B",19,19256377,19303400,-1,"protein_coding",100271849,"MEF2B",0.590447262915793,"NA",56,12.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":8.2e-42,"d":"8.20E-42"},"rs113954889;rs28672836;19:19260892_CAAAAAAAAA_C;rs73001020:rs2285626;19:19510831_AT_A;rs17216693:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs187429064:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000254901","MEF2BNB",19,19287712,19303400,-1,"protein_coding",729991,"MEF2BNB","NA",0.579437175,21,9.408,12,{"v":1.42511E-7,"d":"1.43E-07"},{"v":3.62201e-19,"d":"3.62E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":8.2e-42,"d":"8.20E-42"},"rs113954889;rs8100140;rs73001020:rs2285626;19:19510831_AT_A;rs17216693:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs187429064:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000064490","RFXANK",19,19303008,19312678,1,"protein_coding",8625,"RFXANK",0.000671163624692492,0.789997306,9,9.408,3,0.000100607,0.0177117,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":8.2e-42,"d":"8.20E-42"},"rs113954889;rs8100140;rs187429064;rs73001020;rs73001020:rs2285626;19:19510831_AT_A;rs17216693:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs187429064:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000184162","NR2C2AP",19,19312225,19314233,-1,"protein_coding",126382,"NR2C2AP",0.527167735331819,-0.417894074,2,6.326,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3e-40,"d":"3.00E-40"},"rs8100140;rs187429064;rs113954889:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs58542926:rs2285626",44]
["ENSG00000130287","NCAN",19,19322782,19363042,1,"protein_coding",1463,"NCAN",0.154546738217425,-1.280770396,7,23,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":8.6e-46,"d":"8.60E-46"},"rs8100140;rs187429064;rs3761077;rs58542926;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs187429064:19:19510831_AT_A:19:19617705_CTTTAA_C",44]
["ENSG00000187664","HAPLN4",19,19366450,19373605,-1,"protein_coding",404037,"HAPLN4",0.0326847848265823,0.204997517,17,26.2,197,{"v":6.79586E-20,"d":"6.80E-20"},{"v":6.88492e-19,"d":"6.88E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","EP_correlation_cell_type_oneway",{"v":6.6e-46,"d":"6.60E-46"},"rs58542926;rs11882123;rs2285626;19:19510831_AT_A;rs187429064;rs17216693;rs7245672;rs143333049;rs8100204",44]
["ENSG00000213996","TM6SF2",19,19375173,19384200,-1,"protein_coding",53345,"TM6SF2",{"v":1.93541173325793e-05,"d":"1.94E-05"},"NA",35,26.2,264,{"v":1.17275e-20,"d":"1.17E-20"},{"v":8.90299e-16,"d":"8.90E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":6.6e-46,"d":"6.60E-46"},"rs58542926;rs11882123;rs2285626;19:19510831_AT_A;rs187429064;rs35431065;rs8100204;rs17216693;rs7245672;19:19756073_AGCC_A;rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs187429064:rs3761077:rs58542926;rs3761077:19:19617705_CTTTAA_C",44]
["ENSG00000105705","SUGP1",19,19386827,19431653,-1,"protein_coding",57794,"SUGP1",0.9996355600486,"NA",84,26.2,12,{"v":4.84498e-06,"d":"4.84E-06"},{"v":5.87709e-05,"d":"5.88E-05"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":6.6e-46,"d":"6.60E-46"},"rs11882123;rs58542926;rs187429064;rs2285626;19:19510831_AT_A;rs35431065;rs8100204;rs73001020;rs17216693;19:19438110_GTATT_G;rs7245672;rs11882123:rs2285626:rs2285626",44]
["ENSG00000129933","MAU2",19,19431490,19469563,1,"protein_coding",23383,"MAU2",0.999717755369344,0.014423646,86,15.92,20,{"v":2.45442e-05,"d":"2.45E-05"},0.0377692,"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":1.1E-41,"d":"1.10E-41"},"rs2285626;19:19510831_AT_A;rs11882123;rs58542926;19:19438110_GTATT_G;rs73001020;rs187429064;19:19617705_CTTTAA_C;rs11882123:rs2285626:rs2285626",44]
["ENSG00000167491","GATAD2A",19,19496635,19619740,1,"protein_coding",54815,"GATAD2A",0.995362828250654,-0.496926306,121,19.09,29,{"v":9.95736e-06,"d":"9.96E-06"},0.0106309,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":6e-42,"d":"6.00E-42"},"rs11882123;rs2285626;19:19510831_AT_A;rs58542926;19:19756073_AGCC_A;rs17216693;rs73001020;rs77653002;19:19617705_CTTTAA_C;rs143729015:rs11882123:rs58542926:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000178093","TSSK6",19,19623227,19626838,-1,"protein_coding",83983,"TSSK6",0.587550746537451,-1.568432771,20,19.09,25,{"v":8.90205e-06,"d":"8.90E-06"},{"v":3.58402e-05,"d":"3.58E-05"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex",{"v":1.8E-31,"d":"1.80E-31"},"rs11882123;rs2285626;19:19617705_CTTTAA_C;19:19510831_AT_A;rs17216693;rs7245672;rs11882123:rs2285626",44]
["ENSG00000186010","NDUFA13",19,19626545,19644285,1,"protein_coding",51079,"NDUFA13",1.21026586319051E-4,-0.285091511,23,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-31,"d":"7.20E-31"},"rs11882123;19:19617705_CTTTAA_C;rs2285626;19:19510831_AT_A;rs17216693;rs11882123:rs2285626",44]
["ENSG00000250067","YJEFN3",19,19627036,19648390,1,"protein_coding",374887,"YJEFN3",{"v":2.63542608769062e-06,"d":"2.64E-06"},"NA",23,19.09,219,{"v":1.26288E-18,"d":"1.26E-18"},{"v":3.19891e-16,"d":"3.20E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex",{"v":8.6e-46,"d":"8.60E-46"},"rs11882123;19:19617705_CTTTAA_C;rs2285626;19:19510831_AT_A;rs17216693;rs58542926;rs73001020;19:19756073_AGCC_A;rs7245672;rs143729015;rs11882123:rs2285626",44]
["ENSG00000258674","CTC-260F20.3",19,19627036,19646885,1,"protein_coding","NA","NA","NA","NA",21,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-31,"d":"7.20E-31"},"rs11882123;19:19617705_CTTTAA_C;rs2285626;19:19510831_AT_A;rs17216693;rs11882123:rs2285626",44]
["ENSG00000160161","CILP2",19,19649057,19657468,1,"protein_coding",148113,"CILP2",0.000278936233123941,-0.132917182,15,11.63,165,{"v":2.5641e-19,"d":"2.56E-19"},{"v":7.52088e-21,"d":"7.52E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":8.2e-42,"d":"8.20E-42"},"rs11882123;rs2285626;19:19510831_AT_A;rs17216693;rs58542926;rs7245672;rs187429064:rs3761077:rs58542926;rs3761077:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:19:19617705_CTTTAA_C:rs2285626;rs17216693:rs58542926;19:19756073_AGCC_A:rs7245672",44]
["ENSG00000105717","PBX4",19,19672522,19729725,-1,"protein_coding",80714,"PBX4",0.006772126187306,-0.679896521,36,8.295,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2e-39,"d":"1.20E-39"},"rs58542926;rs17216693;rs7245672;19:19756073_AGCC_A;rs7245672:rs58542926",44]
["ENSG00000064547","LPAR2",19,19734477,19739739,-1,"protein_coding",9170,"LPAR2",0.337269896843433,-0.426142953,8,7.735,167,{"v":3.08297e-26,"d":"3.08E-26"},{"v":1.22846e-27,"d":"1.23E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":4.2e-39,"d":"4.20E-39"},"rs7245672;rs58542926;19:19756073_AGCC_A;rs11882123",44]
["ENSG00000089639","GMIP",19,19740285,19754476,-1,"protein_coding",51291,"GMIP",{"v":7.29298933296636e-05,"d":"7.29E-05"},-0.277164354,6,8.763,13,{"v":7.22479e-08,"d":"7.22E-08"},1.36079E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","-","Yes","EP_correlation_cell_type_oneway",{"v":1.6e-36,"d":"1.60E-36"},"rs7245672;rs58542926;19:19756073_AGCC_A;rs11882123",44]
["ENSG00000105726","ATP13A1",19,19756007,19774502,-1,"protein_coding",57130,"ATP13A1",0.994473888962369,"NA",2,8.763,102,{"v":3.16696e-16,"d":"3.17E-16"},{"v":9.80314e-12,"d":"9.80E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":6.6e-46,"d":"6.60E-46"},"rs58542926;19:19756073_AGCC_A;rs143729015;rs113954889;rs3761077;rs35431065;rs8100204;rs73001020;rs17216693;rs2285626;19:19510831_AT_A;rs143333049;rs7245672;rs7245672:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs11882123:rs58542926:rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000181896","ZNF101",19,19779605,19794318,1,"protein_coding",94039,"ZNF101",{"v":5.76614320550034e-07,"d":"5.77E-07"},-0.001974248,5,11.91,44,{"v":2.56484E-5,"d":"2.56E-05"},{"v":2.22273E-14,"d":"2.22E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":8.2e-42,"d":"8.20E-42"},"19:19756073_AGCC_A;rs143333049;rs113954889;rs58542926;rs3761077;rs7245672;rs11882123:rs7245672:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs58542926:rs2285626:19:19617705_CTTTAA_C",44]
["ENSG00000105708","ZNF14",19,19821280,19843906,-1,"protein_coding",7561,"ZNF14",{"v":5.71582699182454e-16,"d":"5.72E-16"},-0.140934352,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Fetal_Cortex:Mesendoderm",{"v":3e-40,"d":"3.00E-40"},"rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:19:19756073_AGCC_A:rs143333049",44]
["ENSG00000081665","ZNF506",19,19896648,19932560,-1,"protein_coding",440515,"ZNF506",{"v":1.99612668014446E-8,"d":"2.00E-08"},-0.298399589,0,0,14,{"v":4.66246e-05,"d":"4.66E-05"},{"v":1.69948E-26,"d":"1.70E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Left_Ventricle","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6e-42,"d":"6.00E-42"},"rs58542926;rs17216693;19:19756073_AGCC_A;rs73001020;rs2285626;19:19756073_AGCC_A:rs7245672:rs143333049:19:19756073_AGCC_A",44]
["ENSG00000256771","ZNF253",19,19976695,20005483,1,"protein_coding",56242,"ZNF253",{"v":1.33295852799606e-06,"d":"1.33E-06"},0.279040894,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.9E-13,"d":"1.90E-13"},"rs143333049",44]
["ENSG00000184635","ZNF93",19,20011722,20046384,1,"protein_coding",81931,"ZNF93",0.00169182185612759,0.174728697,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.3e-39,"d":"4.30E-39"},"rs143333049:rs58542926;19:19756073_AGCC_A:rs7245672:19:19756073_AGCC_A",44]
["ENSG00000268461","AC007204.1",19,20047769,20048639,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-39,"d":"1.20E-39"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A;rs17216693:rs58542926;rs17216693:rs17216693:rs7245672:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs143333049",44]
["ENSG00000197124","ZNF682",19,20107867,20150315,-1,"protein_coding",91120,"ZNF682",{"v":3.67329437341058e-09,"d":"3.67E-09"},1.212036464,0,0,1,{"v":9.3218e-05,"d":"9.32E-05"},0.00051934,"GTEx/v8/Artery_Tibial","-","No","NA",{"v":8.6e-46,"d":"8.60E-46"},"rs58542926",44]
["ENSG00000213988","ZNF90",19,20188803,20237885,1,"protein_coding",7643,"ZNF90",{"v":1.22410273221888e-07,"d":"1.22E-07"},1.219480619,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049",44]
["ENSG00000256229","ZNF486",19,20278037,20311299,1,"protein_coding",90649,"ZNF486",{"v":1.88053183954875e-08,"d":"1.88E-08"},1.705728223,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672",44]
["ENSG00000237440","ZNF737",19,20718631,20748615,-1,"protein_coding",100129842,"ZNF737",{"v":1.10579189398794E-7,"d":"1.11E-07"},1.355633218,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.9E-13,"d":"1.90E-13"},"rs143333049",44]
["ENSG00000188171","ZNF626",19,20802867,20844402,-1,"protein_coding",199777,"ZNF626",{"v":2.3449662444854E-7,"d":"2.34E-07"},10.77102824,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672",44]
["ENSG00000118620","ZNF430",19,21203426,21242856,1,"protein_coding",80264,"ZNF430",0.000180790697407956,0.502386975,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049",44]
["ENSG00000160352","ZNF714",19,21264965,21308073,1,"protein_coding",148206,"ZNF714",{"v":7.33708061274363e-06,"d":"7.34E-06"},0.728801136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672",44]
["ENSG00000182141","ZNF708",19,21473962,21512227,-1,"protein_coding",7562,"ZNF708",{"v":4.17756094613551e-09,"d":"4.18E-09"},1.095220078,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049:19:19756073_AGCC_A",44]
["ENSG00000172687","ZNF738",19,21541732,21562104,1,"protein_coding",148203,"ZNF738",0.106373218916856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049",44]
["ENSG00000196268","ZNF493",19,21579921,21610375,1,"protein_coding",284443,"ZNF493",{"v":3.18649368326509e-08,"d":"3.19E-08"},2.729194243,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672:19:19756073_AGCC_A:rs143333049",44]
["ENSG00000269237","CTD-2561J22.3",19,21587961,21674068,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672:19:19756073_AGCC_A:rs143333049",44]
["ENSG00000197013","ZNF429",19,21679484,21739072,1,"protein_coding",353088,"ZNF429",{"v":9.7121420957407e-14,"d":"9.71E-14"},-0.124310103,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.3e-39,"d":"4.30E-39"},"rs58542926;19:19756073_AGCC_A:rs7245672",44]
["ENSG00000197020","ZNF100",19,21905568,21950430,-1,"protein_coding",163227,"ZNF100",{"v":7.10189425692909e-13,"d":"7.10E-13"},1.454526972,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.9E-13,"d":"1.90E-13"},"rs143333049",44]
["ENSG00000197360","ZNF98",19,22573821,22715287,-1,"protein_coding",148198,"ZNF98",{"v":1.80227058167028E-6,"d":"1.80E-06"},0.029177521,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.9E-13,"d":"1.90E-13"},"rs143333049",44]
["ENSG00000188493","C19orf54",19,41246761,41257458,-1,"protein_coding",284325,"C19orf54",0.00126594510562578,0.052287889,0,0,3,{"v":6.16002e-05,"d":"6.16E-05"},{"v":3.04102e-20,"d":"3.04E-20"},"GTEx/v8/Artery_Aorta","-","No","NA",{"v":7.1e-06,"d":"7.10E-06"},"rs56113850",45]
["ENSG00000268797","CTC-490E21.12",19,41307202,41404187,1,"protein_coding","NA","NA","NA","NA",12,11.13,0,"NA","NA","NA","NA","No","NA",{"v":5e-09,"d":"5.00E-09"},"rs56113850",45]
["ENSG00000255974","CYP2A6",19,41349443,41356352,-1,"protein_coding",1548,"CYP2A6",{"v":2.17794878373007e-06,"d":"2.18E-06"},0.721351243,9,11.13,3,{"v":2.49506e-06,"d":"2.50E-06"},0.0145809,"GTEx/v8/Liver","+","No","NA",{"v":5e-09,"d":"5.00E-09"},"rs56113850",45]
["ENSG00000197838","CYP2A13",19,41594377,41602100,1,"protein_coding",1553,"CYP2A13",0.00143445702978295,0.037474477,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":5e-09,"d":"5.00E-09"},"rs56113850",45]
["ENSG00000167600","CYP2S1",19,41698954,41713444,1,"protein_coding",29785,"CYP2S1",0.000914984181302337,-0.036779085,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.1e-06,"d":"7.10E-06"},"rs56113850",45]
["ENSG00000007129","CEACAM21",19,42055886,42093197,1,"protein_coding",90273,"CEACAM21",{"v":2.37927718675089e-10,"d":"2.38E-10"},0.224041523,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesendoderm:hESC",{"v":5e-09,"d":"5.00E-09"},"rs56113850:rs62116778",1.9069444444444443]
["ENSG00000105352","CEACAM4",19,42125344,42133442,-1,"protein_coding",1089,"CEACAM4",{"v":1.67959503585306e-06,"d":"1.68E-06"},0.380841519,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000007306","CEACAM7",19,42177235,42210895,-1,"protein_coding",1087,"CEACAM7",{"v":9.14464756921175e-07,"d":"9.14E-07"},-0.513121247,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000105388","CEACAM5",19,42212504,42233718,1,"protein_coding",1048,"CEACAM5",{"v":3.66899588817934e-05,"d":"3.67E-05"},-0.198121862,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000267881","CEA",19,42212531,42265190,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000183103","LYPD4",19,42341148,42348760,-1,"protein_coding",147719,"LYPD4",{"v":3.41494476753975E-5,"d":"3.41E-05"},-0.551774341,0,0,0,"NA","NA","NA","NA","Yes","hESC",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000142025","DMRTC2",19,42348806,42356401,1,"protein_coding",63946,"DMRTC2",0.726527694192844,-0.470761653,0,0,0,"NA","NA","NA","NA","Yes","hESC",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000079435","LIPE",19,42905659,42931578,-1,"protein_coding",3991,"LIPE",{"v":5.7325054658036e-09,"d":"5.73E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.8e-09,"d":"5.80E-09"},"rs62116778:rs151330717",46]
["ENSG00000189377","CXCL17",19,42932440,42947200,-1,"protein_coding",284340,"CXCL17",0.0285883727188355,0.421463847,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.8e-09,"d":"5.80E-09"},"rs62116778:rs151330717",46]
["ENSG00000124469","CEACAM8",19,43084393,43099207,-1,"protein_coding",1088,"CEACAM8",{"v":1.24548133374918E-7,"d":"1.25E-07"},-0.378062842,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000124467","PSG8",19,43256838,43359843,-1,"protein_coding",440533,"PSG8",{"v":1.92926054362959E-10,"d":"1.93E-10"},-0.013341309,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":8.3e-09,"d":"8.30E-09"},"rs62116778",46]
["ENSG00000183668","PSG9",19,43715943,43773682,-1,"protein_coding",5678,"PSG9",{"v":2.7470177840116e-14,"d":"2.75E-14"},0.713823935,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000167378","IRGQ",19,44088521,44100287,-1,"protein_coding",126298,"IRGQ",1.19722791198288E-3,-1.836457701,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839",46]
["ENSG00000124444","ZNF576",19,44100544,44105309,1,"protein_coding",79177,"ZNF576",0.007545747912442,-1.085568404,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839",46]
["ENSG00000226763","SRRM5",19,44100769,44118649,1,"protein_coding",100170229,"SRRM5",{"v":7.19141934794887e-06,"d":"7.19E-06"},-0.661940966,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839",46]
["ENSG00000131116","ZNF428",19,44111371,44124026,-1,"protein_coding",126299,"ZNF428",0.720275479182866,-0.650154352,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6E-50,"d":"1.60E-50"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754",46]
["ENSG00000105767","CADM4",19,44126520,44143991,-1,"protein_coding",199731,"CADM4",0.979491544538579,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6E-50,"d":"1.60E-50"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754",46]
["ENSG00000124449","IRGC",19,44220162,44224173,1,"protein_coding",56269,"IRGC",0.0437355066124445,0.538293874,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":5.8e-09,"d":"5.80E-09"},"rs151330717:rs62116778",46]
["ENSG00000105771","SMG9",19,44235301,44259142,-1,"protein_coding",56006,"SMG9",{"v":4.84811349964517e-11,"d":"4.85E-11"},0.280820638,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000104783","KCNN4",19,44270685,44285409,-1,"protein_coding",3783,"KCNN4",{"v":8.36465970463448e-06,"d":"8.36E-06"},-0.056751192,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2e-06,"d":"2.00E-06"},"rs62116778",46]
["ENSG00000159871","LYPD5",19,44300081,44331358,-1,"protein_coding",284348,"LYPD5",{"v":9.4450522196327e-05,"d":"9.45E-05"},1.755971449,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-47,"d":"1.90E-47"},"rs62116778:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs151330717",46]
["ENSG00000167637","ZNF283",19,44331444,44353307,1,"protein_coding",284349,"ZNF283",{"v":4.46246793803596E-8,"d":"4.46E-08"},1.259853166,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-47,"d":"1.90E-47"},"rs62116778:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs151330717",46]
["ENSG00000176222","ZNF404",19,44376515,44405537,-1,"protein_coding",342908,"ZNF404",{"v":1.48958552341176E-5,"d":"1.49E-05"},0.204290579,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000124459","ZNF45",19,44416781,44439430,-1,"protein_coding",7596,"ZNF45",1.0251198832844E-4,0.299070466,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000159905","ZNF221",19,44455375,44471861,1,"protein_coding",7638,"ZNF221",{"v":2.58051484113414e-09,"d":"2.58E-09"},-0.128373786,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Bladder:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.9e-47,"d":"1.90E-47"},"rs62116778:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",46]
["ENSG00000204920","ZNF155",19,44472014,44502477,1,"protein_coding",7711,"ZNF155",{"v":1.33952561088838e-09,"d":"1.34E-09"},0.435175767,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Bladder:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.9e-47,"d":"1.90E-47"},"rs62116778:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",46]
["ENSG00000159882","ZNF230",19,44507100,44518078,1,"protein_coding",7773,"ZNF230",0.00834108463646319,1.880496895,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138:rs62116778:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs151330717:rs62119267",46]
["ENSG00000159885","ZNF222",19,44529494,44537265,1,"protein_coding",7673,"ZNF222",{"v":9.20501288480146e-11,"d":"9.21E-11"},0.148041701,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs151330717:rs62119267",46]
["ENSG00000267022","ZNF223",19,44529506,44591471,1,"protein_coding",7766,"ZNF223","NA",0.204654881,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs151330717:rs62119267",46]
["ENSG00000178386","ZNF223",19,44555520,44572144,1,"protein_coding",7766,"ZNF223",{"v":5.14224553323192e-09,"d":"5.14E-09"},0.204654881,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs151330717:rs62119267",46]
["ENSG00000186026","ZNF284",19,44576297,44593766,1,"protein_coding",342909,"ZNF284",{"v":7.90018316515337e-09,"d":"7.90E-09"},0.721071866,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000267680","ZNF224",19,44598492,44612479,1,"protein_coding",7767,"ZNF224",{"v":2.0744645910844e-09,"d":"2.07E-09"},-0.281087996,1,1.447,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778;rs62116778:rs62119267",46]
["ENSG00000256294","ZNF225",19,44616334,44637027,1,"protein_coding",7768,"ZNF225",{"v":3.36669333303033e-08,"d":"3.37E-08"},0.547354183,1,1.447,1,1.18239E-4,0.00794975,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Left_Ventricle:Liver:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs62116778;rs145887105;rs62116778:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs111784051:rs558516697:rs4803767:rs395908:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs144261139:rs2238681:rs11556505:rs1081105:rs157581:rs429358;rs11556505;rs157581:rs157580:rs429358;rs157581:rs11668327:19:45402389_CA_C:rs449647:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs151330717",46]
["ENSG00000263002","ZNF234",19,44645710,44663156,1,"protein_coding",10780,"ZNF234",{"v":1.07736675935267E-13,"d":"1.08E-13"},-0.020937289,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000167380","ZNF226",19,44669226,44682534,1,"protein_coding",7769,"ZNF226",{"v":5.26919185197287e-15,"d":"5.27E-15"},-0.050655376,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000131115","ZNF227",19,44711700,44741421,1,"protein_coding",7770,"ZNF227",{"v":1.69159989152872e-05,"d":"1.69E-05"},0.350230355,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs151330717:rs62119267",46]
["ENSG00000159917","ZNF235",19,44732882,44809199,-1,"protein_coding",9310,"ZNF235",{"v":1.85820362433789E-10,"d":"1.86E-10"},-0.818454032,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-47,"d":"1.90E-47"},"rs62116778:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",46]
["ENSG00000159915","ZNF233",19,44754318,44779470,1,"protein_coding",353355,"ZNF233",{"v":3.27015906549736e-17,"d":"3.27E-17"},-0.066961399,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-25,"d":"1.20E-25"},"rs62116778:rs151330717:rs62119267:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918",46]
["ENSG00000062370","ZNF112",19,44830708,44871377,-1,"protein_coding",7771,"ZNF112",0.154211257518811,0.038237323,1,3.21,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.9e-47,"d":"1.90E-47"},"rs62116778;rs62116778:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918",46]
["ENSG00000267173","CTC-512J12.6",19,44833848,44905774,-1,"protein_coding","NA","NA","NA","NA",2,3.21,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778;rs62116778:rs62119267",46]
["ENSG00000267508","ZNF285",19,44886459,44905774,-1,"protein_coding",26974,"ZNF285",0.00240305532090865,0.299255157,1,2.232,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778;rs62116778:rs62119267",46]
["ENSG00000167383","ZNF229",19,44921685,44952766,-1,"protein_coding",7772,"ZNF229",{"v":6.30663414582273e-09,"d":"6.31E-09"},2.836421684,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000167384","ZNF180",19,44979854,45004576,-1,"protein_coding",7733,"ZNF180",{"v":7.35726181171227e-06,"d":"7.36E-06"},0.745753328,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.1e-12,"d":"2.10E-12"},"rs62116778:rs62119267",46]
["ENSG00000216588","IGSF23",19,45116940,45140081,1,"protein_coding",147710,"IGSF23","NA",0.573724812,2,3.57,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6E-50,"d":"1.60E-50"},"rs151330717;rs62119267;rs62117206:rs62119267:rs151330717:rs11881756:19:45224670_GA_G:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs62116778:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918",46]
["ENSG00000073008","PVR",19,45147098,45166850,1,"protein_coding",5817,"PVR",{"v":5.51101308161619e-07,"d":"5.51E-07"},-0.732916848,6,11.21,6,{"v":2.88042e-08,"d":"2.88E-08"},{"v":1.93464E-13,"d":"1.93E-13"},"GTEx/v8/Artery_Tibial","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs62119267;rs151330717:rs62116778:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs62119267:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100",46]
["ENSG00000186567","CEACAM19",19,45165545,45187631,1,"protein_coding",56971,"CEACAM19",{"v":5.7765093789489e-07,"d":"5.78E-07"},0.414157593,13,12.01,13,{"v":8.1714e-11,"d":"8.17E-11"},{"v":6.52332e-14,"d":"6.52E-14"},"GTEx/v8/Artery_Tibial","+","Yes","Liver:IMR90:Mesenchymal_Stem_Cell",{"v":1.6E-50,"d":"1.60E-50"},"rs62119267;rs151330717;rs151330717:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754",46]
["ENSG00000213892","CEACAM16",19,45202421,45213986,1,"protein_coding",388551,"CEACAM16",0.0295802581415047,-0.586640098,14,12.82,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":6e-76,"d":"6.00E-76"},"rs151330717;rs62119267;rs11881756;rs112450640;19:45311297_AGCTTG_A;19:45303122_AAAAG_A:rs112450640:rs113914212:rs148933445:19:45311297_AGCTTG_A:19:45303122_AAAAG_A:rs140824606:rs28399607:rs41290120;rs62117160:rs62116778:rs151330717:rs62119267:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754",46]
["ENSG00000069399","BCL3",19,45250962,45263301,1,"protein_coding",602,"BCL3",0.86217268510329,"NA",18,16.89,0,"NA","NA","NA","NA","No","NA",{"v":1.8E-37,"d":"1.80E-37"},"rs200046586;rs62117206;rs4803748;rs148933445;rs10401176;rs140824606",46]
["ENSG00000142273","CBLC",19,45281126,45303891,1,"protein_coding",23624,"CBLC",1.82989540193376E-4,-0.348046092,33,15.89,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-50,"d":"1.20E-50"},"19:45276590_GTTA_G;rs112450640;19:45311297_AGCTTG_A;19:45303122_AAAAG_A;rs113914212;rs148933445;rs140824606;19:45531618_GT_G;rs149553138:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",46]
["ENSG00000187244","BCAM",19,45312328,45324673,1,"protein_coding",4059,"BCAM",0.0368511835228543,"NA",51,15.96,2,{"v":3.9611e-08,"d":"3.96E-08"},0.000117881,"GTEx/v8/Artery_Tibial","+","Yes","Left_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":6e-76,"d":"6.00E-76"},"rs148933445;rs113914212;19:45311297_AGCTTG_A;19:45303122_AAAAG_A;rs140824606;rs28399607;rs41290120;rs62117160;rs766396778;rs28399637;rs2927482;rs149214960;rs752060506;19:45328407_GAC_G;rs6509173;rs7343130;rs2927472;rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs112588918:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",46]
["ENSG00000130202","PVRL2",19,45349432,45392485,1,"protein_coding",5819,"PVRL2",0.531937435077773,-0.314456223,125,21.1,43,{"v":1.60823E-20,"d":"1.61E-20"},{"v":1.20145E-26,"d":"1.20E-26"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":8.1e-86,"d":"8.10E-86"},"rs2927482;rs149214960;rs112588918;rs41289514;rs2927472;rs111371860;rs566486324;rs3810143;rs71338733;rs2972558;rs375972689;rs12463239;rs3729640;rs768441224;rs33951304;rs111784051;rs558516697;rs4803767;rs395908;rs548051568;rs393584;rs6859;rs41290120;rs1985129;rs144261139;rs2238681;rs11556505;rs1081105;rs157581;rs429358;rs157580;rs11668327;19:45402389_CA_C;19:45311297_AGCTTG_A;rs7343130;rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs111784051:rs112450640;19:45303122_AAAAG_A:rs112450640:rs113914212:rs148933445:19:45311297_AGCTTG_A:19:45303122_AAAAG_A:rs140824606:rs28399607:rs41290120;rs62117160:rs62116778:rs62119267:rs151330717:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",46]
["ENSG00000130204","TOMM40",19,45393826,45406946,1,"protein_coding",10452,"TOMM40",0.963682323765023,"NA",80,25.1,2,{"v":4.48241e-05,"d":"4.48E-05"},4.8747E-3,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.9e-141,"d":"4.90E-141"},"rs1985129;rs144261139;rs2238681;rs11556505;rs1081105;rs111784051;rs157581;rs429358;rs157580;rs11668327;19:45402389_CA_C;rs449647;rs75627662;rs59325138;rs1065853;rs157595;rs3925681:rs1081105:rs374095935:rs157592:rs71352239;rs3925681:rs157595:rs429358;rs157592:rs144311893:rs1065853:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:rs57465754:19:45531618_GT_G;rs149553138:rs62116778:rs79429216:rs12721109",46]
["ENSG00000130203","APOE",19,45409011,45412650,1,"protein_coding",348,"APOE",0.0345335830833016,-0.237445173,50,25.1,9,{"v":1.25337E-5,"d":"1.25E-05"},0.0289608,"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs1081105;rs111784051;rs2238681;19:45402389_CA_C;rs449647;rs157580;rs429358;rs11556505;rs75627662;rs59325138;rs1065853;rs157595;rs3925681;rs374095935;rs157592;rs71352239;rs111606839;rs62117206:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs62116778:rs62119267",46]
["ENSG00000130208","APOC1",19,45417504,45422606,1,"protein_coding",341,"APOC1",0.0507382728810443,-0.105569458,48,25.1,7,{"v":3.55555e-06,"d":"3.56E-06"},0.00882724,"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs2238681;rs449647;rs157580;rs429358;rs11556505;rs75627662;rs59325138;rs1065853;rs1081105;rs157595;rs3925681;rs374095935;rs157592;rs71352239;rs144311893;rs60049679;rs5112;rs7246100;rs62117206:rs5112:rs5112;rs7246100:rs7246100:19:45440145_CTG_C:rs111606839:19:45531618_GT_G;rs149553138:rs79429216:rs12721109:rs57465754:rs62116778:rs62119267",46]
["ENSG00000224916","APOC4-APOC2",19,45445495,45452822,1,"protein_coding",100533990,"APOC4-APOC2","NA","NA",37,17.4,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs7246100;19:45440145_CTG_C;rs111606839;rs79429216;rs12721109;rs62117206:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7245887:rs145887105:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs558516697:rs4803767:rs395908:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs144261139:rs11556505:rs157581:rs429358;rs157581:rs429358;rs157581:rs11668327:rs79890446",46]
["ENSG00000267467","APOC4",19,45445495,45452820,1,"protein_coding",346,"APOC4",0.000150692347626422,0.337274035,37,17.4,50,{"v":4.4607e-14,"d":"4.46E-14"},{"v":3.56734e-09,"d":"3.57E-09"},"GTEx/v8/Liver","+","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs7246100;19:45440145_CTG_C;rs111606839;rs79429216;rs12721109;rs57465754;rs7245887;rs62117206:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7245887:rs145887105:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs558516697:rs4803767:rs395908:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs144261139:rs11556505:rs157581:rs429358;rs157581:rs429358;rs157581:rs11668327:rs79890446",46]
["ENSG00000234906","APOC2",19,45449243,45452822,1,"protein_coding",344,"APOC2",0.0227961322934307,0.388732718,34,17.4,59,{"v":5.34361e-12,"d":"5.34E-12"},{"v":1.21381e-15,"d":"1.21E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"19:45440145_CTG_C;rs111606839;rs79429216;rs12721109;rs5112;rs62117206:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7245887:rs145887105:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs558516697:rs4803767:rs395908:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs144261139:rs11556505:rs157581:rs429358;rs157581:rs429358;rs157581:rs11668327:rs79890446",46]
["ENSG00000267114","CTB-129P6.11",19,45453301,45457264,-1,"protein_coding","NA","NA","NA","NA",28,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs111606839;rs79429216;19:45440145_CTG_C;rs12721109;rs57465754;rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs111784051:rs157581:rs429358;rs11556505;rs157581:rs144261139:rs11556505:rs157580:rs2238681:rs429358;rs157581:rs1081105:rs11668327:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:rs57465754:19:45402389_CA_C:rs449647:rs7245887:rs145887105:19:45531618_GT_G:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs558516697:rs4803767:rs395908:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs79890446",46]
["ENSG00000104853","CLPTM1",19,45457842,45496599,1,"protein_coding",1209,"CLPTM1",0.98048307691788,"NA",63,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"rs111606839;19:45440145_CTG_C;rs57465754;rs117261169;19:45500884_CT_C;rs79429216;rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs111784051:rs157581:rs429358;rs11556505;rs157581:rs144261139:rs11556505:rs157580:rs2238681:rs429358;rs157581:rs1081105:rs11668327:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:rs57465754:19:45402389_CA_C:rs449647:rs7245887:rs145887105:19:45531618_GT_G:rs151330717:rs62119267:rs11881756:19:45224670_GA_G:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs558516697:rs4803767:rs395908:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs79890446",46]
["ENSG00000104856","RELB",19,45504688,45541452,1,"protein_coding",5971,"RELB",0.973562746007932,"NA",35,17.21,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":1.8e-33,"d":"1.80E-33"},"rs111606839;19:45440145_CTG_C;rs57465754;19:45500884_CT_C;rs79429216;19:45506732_CAAAA_C;rs7245887;rs145887105;19:45531618_GT_G;rs149553138;rs62117206",46]
["ENSG00000104859","CLASRP",19,45542298,45574214,1,"protein_coding",11129,"CLASRP",0.964966482147783,-0.085202503,1,1.868,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.9e-141,"d":"4.90E-141"},"19:45531618_GT_G;rs149553138;rs181765708:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs111784051:rs157581:rs429358;rs11556505;rs157581:rs144261139:rs11556505:rs157580:rs2238681:rs429358;rs157581:rs1081105:rs11668327:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:19:45440145_CTG_C:rs111606839:rs57465754:rs7245887:rs145887105:rs79429216:rs12721109:rs79890446",46]
["ENSG00000170684","ZNF296",19,45574758,45579846,-1,"protein_coding",162979,"ZNF296",0.97328866403764,"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"rs181765708:19:45531618_GT_G;rs149553138",46]
["ENSG00000142252","GEMIN7",19,45582453,45594782,1,"protein_coding",79760,"GEMIN7",0.347103990823881,-0.101681128,0,0,16,{"v":1.16893E-5,"d":"1.17E-05"},{"v":4.76054E-23,"d":"4.76E-23"},"GTEx/v8/Artery_Tibial","+","No","NA",{"v":1.1e-08,"d":"1.10E-08"},"19:45440145_CTG_C",46]
["ENSG00000007047","MARK4",19,45582546,45808541,1,"protein_coding",57787,"MARK4",0.999932135718548,"NA",3,7.261,16,{"v":2.43126e-09,"d":"2.43E-09"},{"v":1.70606e-05,"d":"1.71E-05"},"GTEx/v8/Artery_Aorta","-","No","NA",{"v":1.4e-26,"d":"1.40E-26"},"rs12721109;rs149553138;rs79890446;19:45440145_CTG_C",46]
["ENSG00000104866","PPP1R37",19,45594654,45651335,1,"protein_coding",284352,"PPP1R37","NA",0.143949947,1,7.261,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"rs12721109;19:45531618_GT_G;rs149553138",46]
["ENSG00000179846","NKPD1",19,45653008,45663408,-1,"protein_coding",284353,"NKPD1",{"v":1.88741865526868e-09,"d":"1.89E-09"},"NA",2,7.261,0,"NA","NA","NA","NA","No","NA",{"v":1.4e-26,"d":"1.40E-26"},"rs12721109;rs149553138",46]
["ENSG00000007255","TRAPPC6A",19,45666186,45681495,-1,"protein_coding",79090,"TRAPPC6A",0.000705277787371492,-0.133842318,1,0.065,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.9e-141,"d":"4.90E-141"},"rs149553138;rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs1081105:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:rs57465754:19:45531618_GT_G;rs149553138:rs181765708:rs2927482:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143",46]
["ENSG00000189114","BLOC1S3",19,45682003,45685059,1,"protein_coding",388552,"BLOC1S3",0.0184297702580611,-0.115773028,1,0.065,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.9e-141,"d":"4.90E-141"},"rs149553138;rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs1081105:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:rs57465754:19:45531618_GT_G;rs149553138:rs181765708:rs2927482:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143",46]
["ENSG00000267545","AC005779.2",19,45683080,45705702,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.9e-141,"d":"4.90E-141"},"rs429358;rs11556505;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs1081105:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:rs57465754:19:45531618_GT_G;rs149553138:rs181765708:rs2927482:rs149214960;rs112588918:rs112588918:rs41289514:rs2927472:rs111371860:rs566486324:rs3810143",46]
["ENSG00000266958","AC006126.3",19,45690646,45720191,1,"protein_coding","NA","NA","NA","NA",1,0.062,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.2E-50,"d":"1.20E-50"},"rs79890446;rs113914212:rs148933445:19:45311297_AGCTTG_A:19:45303122_AAAAG_A:19:45440145_CTG_C:rs111606839",46]
["ENSG00000130201","EXOC3L2",19,45715879,45737469,-1,"protein_coding",90332,"EXOC3L2",0.925564031557031,"NA",1,0.062,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.6E-50,"d":"1.60E-50"},"rs79890446;19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs7245887:rs145887105:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs181765708",46]
["ENSG00000104879","CKM",19,45809672,45826235,-1,"protein_coding",1158,"CKM",0.00505058616928749,0.03849229,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.6E-50,"d":"1.60E-50"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs79890446:rs7245887:rs145887105:19:45531618_GT_G:19:45531618_GT_G;rs149553138",46]
["ENSG00000104892","KLC3",19,45836692,45854778,1,"protein_coding",147700,"KLC3",{"v":3.15849310261577e-06,"d":"3.16E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.6E-50,"d":"1.60E-50"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs79890446:rs7245887:rs145887105:19:45531618_GT_G:19:45531618_GT_G;rs149553138",46]
["ENSG00000268341","L47234.1",19,45842445,45842639,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6E-50,"d":"1.60E-50"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs79890446",46]
["ENSG00000104884","ERCC2",19,45853095,45874176,-1,"protein_coding",2068,"ERCC2",{"v":3.14163491830693e-13,"d":"3.14E-13"},-0.123245341,1,0.743,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6E-50,"d":"1.60E-50"},"rs181765708;19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:rs57465754:rs79890446",46]
["ENSG00000104881","PPP1R13L",19,45882892,45909607,-1,"protein_coding",10848,"PPP1R13L",0.00265401837731973,-0.293274669,2,0.743,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.3E-12,"d":"7.30E-12"},"rs181765708;rs79890446",46]
["ENSG00000117877","CD3EAP",19,45909467,45914024,1,"protein_coding",10849,"CD3EAP",{"v":5.68877488151799e-05,"d":"5.69E-05"},1.568549218,1,0.241,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.7e-11,"d":"4.70E-11"},"rs181765708;rs79890446",46]
["ENSG00000012061","ERCC1",19,45910591,45982086,-1,"protein_coding",2067,"ERCC1",0.000286883321902936,-0.011078743,1,0.241,6,{"v":2.72709E-5,"d":"2.73E-05"},{"v":8.93421e-09,"d":"8.93E-09"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","GM12878:IMR90",{"v":2.4e-15,"d":"2.40E-15"},"rs181765708;rs2927482",46]
["ENSG00000125740","FOSB",19,45971253,45978437,1,"protein_coding",2354,"FOSB",0.852916176747718,-1.205388313,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":6.6e-33,"d":"6.60E-33"},"rs181765708:19:45531618_GT_G;rs149553138",46]
["ENSG00000125744","RTN2",19,45988547,46000319,-1,"protein_coding",6253,"RTN2",0.636179982447555,"NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":7.3E-12,"d":"7.30E-12"},"rs181765708",46]
["ENSG00000213889","PPM1N",19,45992035,46005768,1,"protein_coding",147699,"PPM1N",1.04897385207125E-4,-0.142647997,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":7.3E-12,"d":"7.30E-12"},"rs181765708",46]
["ENSG00000125753","VASP",19,46009837,46030241,1,"protein_coding",7408,"VASP",0.583670616080661,-0.335330773,1,0.158,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":2.2e-08,"d":"2.20E-08"},"rs181765708",46]
["ENSG00000125746","EML2",19,46110252,46148887,-1,"protein_coding",24139,"EML2",{"v":7.57699496433696e-10,"d":"7.58E-10"},0.190257397,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"rs111606839:rs117261169:19:45440145_CTG_C:rs57465754:19:45500884_CT_C:rs79429216:19:45506732_CAAAA_C:19:45531618_GT_G;rs149553138",46]
["ENSG00000267757","C19orf83",19,46144752,46146098,1,"protein_coding",100287177,"C19orf83","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"rs111606839:rs117261169:19:45440145_CTG_C:rs57465754:19:45500884_CT_C:rs79429216:19:45506732_CAAAA_C:19:45531618_GT_G;rs149553138",46]
["ENSG00000125743","SNRPD2",19,46190712,46195827,-1,"protein_coding",6633,"SNRPD2",0.747515256284436,-0.475801412,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000011478","QPCTL",19,46195741,46207247,1,"protein_coding",54814,"QPCTL",0.000261539862441849,-0.638078993,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000177051","FBXO46",19,46213887,46234162,-1,"protein_coding",23403,"FBXO46",0.876437042044124,0.090543664,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138:rs181765708",46]
["ENSG00000237452","AC074212.3",19,46236509,46267792,1,"protein_coding",388553,"BHMG1",0.376320934323438,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138:rs181765708",46]
["ENSG00000104941","RSPH6A",19,46298968,46318577,-1,"protein_coding",81492,"RSPH6A",{"v":2.54884442731765e-08,"d":"2.55E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.4e-50,"d":"1.40E-50"},"rs5112:rs5112;rs7246100:rs7246100",46]
["ENSG00000125755","SYMPK",19,46318668,46366548,-1,"protein_coding",8189,"SYMPK",0.997278492187137,-0.384639791,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000170608","FOXA3",19,46367247,46377055,1,"protein_coding",3171,"FOXA3",0.395510308295114,-0.452953673,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000176182","MYPOP",19,46393278,46405862,-1,"protein_coding",339344,"MYPOP",0.810391050855017,-0.668694835,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":2.2e-08,"d":"2.20E-08"},"rs181765708",46]
["ENSG00000230510","PPP5D1",19,46984053,47104457,-1,"protein_coding",100506012,"PPP5D1",0.0393450229909042,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000268423","AC011551.3",19,47050313,47104118,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000160014","CALM3",19,47104331,47114050,1,"protein_coding",808,"CALM3",0.580172431977243,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000197380","DACT3",19,47150869,47164395,-1,"protein_coding",147906,"DACT3","NA",0.236210063,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.1e-12,"d":"2.10E-12"},"rs62119267",46]
["ENSG00000090372","STRN4",19,47222764,47250251,-1,"protein_coding",29888,"STRN4",0.999575131657329,-0.5987751,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":6.6e-33,"d":"6.60E-33"},"19:45531618_GT_G;rs149553138",46]
["ENSG00000130751","NPAS1",19,47523077,47549033,1,"protein_coding",4861,"NPAS1",0.916472527076156,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.9e-08,"d":"4.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000130748","TMEM160",19,47549165,47551888,-1,"protein_coding",54958,"TMEM160",0.654855932901688,-0.35853148,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.9e-08,"d":"4.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000118160","SLC8A2",19,47931274,47975425,-1,"protein_coding",6543,"SLC8A2","NA",-0.264690994,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.4e-06,"d":"4.40E-06"},"rs8111874",47]
["ENSG00000188334","BSPH1",19,48471303,48495427,-1,"protein_coding",100131137,"BSPH1","NA",0.175619018,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5.5e-07,"d":"5.50E-07"},"rs8111874",47]
["ENSG00000169393","ELSPBP1",19,48497908,48528410,1,"protein_coding",64100,"ELSPBP1",0.000181420081969443,0.488844956,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5.5e-07,"d":"5.50E-07"},"rs8111874",47]
["ENSG00000105483","CARD8",19,48684027,48759203,-1,"protein_coding",22900,"CARD8",0.0162893753878883,2.375586588,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":5.5e-07,"d":"5.50E-07"},"rs8111874",47]
["ENSG00000105447","GRWD1",19,48949030,48960279,1,"protein_coding",83743,"GRWD1",0.337778593629583,0.963374045,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":5.5e-07,"d":"5.50E-07"},"rs8111874",47]
["ENSG00000182324","KCNJ14",19,48958766,48969367,1,"protein_coding",3770,"KCNJ14",{"v":8.51179265459349e-05,"d":"8.51E-05"},1.023716349,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":5.5e-07,"d":"5.50E-07"},"rs8111874",47]
["ENSG00000088002","SULT2B1",19,49055332,49102682,1,"protein_coding",6820,"SULT2B1",0.827919001656143,0.006419371,0,0,1,{"v":3.37192e-05,"d":"3.37E-05"},{"v":7.35172e-19,"d":"7.35E-19"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":1e-06,"d":"1.00E-06"},"rs8111874",47]
["ENSG00000063177","RPL18",19,49118585,49122793,-1,"protein_coding",6141,"RPL18",0.554781180671353,-0.9363722,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.4e-06,"d":"4.40E-06"},"rs8111874",47]
["ENSG00000063176","SPHK2",19,49122548,49133974,1,"protein_coding",56848,"SPHK2",{"v":8.66423863572204e-06,"d":"8.66E-06"},-1.641176237,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.4e-06,"d":"4.40E-06"},"rs8111874",47]
["ENSG00000063180","CA11",19,49141199,49149569,-1,"protein_coding",770,"CA11",0.976097038480165,-0.946174737,1,7.732,0,"NA","NA","NA","NA","No","NA",{"v":5.5e-07,"d":"5.50E-07"},"rs8111874",47]
["ENSG00000142233","NTN5",19,49164664,49176338,-1,"protein_coding",126147,"NTN5",{"v":3.27017246498834e-06,"d":"3.27E-06"},-0.402192771,3,7.732,33,{"v":4.34105e-06,"d":"4.34E-06"},0.000447775,"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","No","NA",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000176920","FUT2",19,49199228,49209207,1,"protein_coding",2524,"FUT2",{"v":5.46581459214613e-12,"d":"5.47E-12"},4.200433008,38,52,38,{"v":2.64666e-63,"d":"2.65E-63"},{"v":1.45969e-53,"d":"1.46E-53"},"GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000176909","MAMSTR",19,49215999,49222978,-1,"protein_coding",284358,"MAMSTR",1.23325809401916E-3,-0.052031801,38,52,38,{"v":6.2349e-18,"d":"6.23E-18"},{"v":2.98816e-20,"d":"2.99E-20"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000105538","RASIP1",19,49223844,49243978,-1,"protein_coding",54922,"RASIP1",0.975494281851725,-0.599190215,3,13.01,29,{"v":4.54663e-06,"d":"4.55E-06"},{"v":7.9078e-05,"d":"7.91E-05"},"GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000182264","IZUMO1",19,49244109,49250166,-1,"protein_coding",284359,"IZUMO1",0.00241626337305742,0.753533326,0,0,24,{"v":8.76584e-06,"d":"8.77E-06"},{"v":9.97708e-19,"d":"9.98E-19"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000174951","FUT1",19,49251268,49258647,-1,"protein_coding",2523,"FUT1",0.000508774873537715,0.370474173,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000105550","FGF21",19,49258816,49261587,1,"protein_coding",26291,"FGF21",0.213002020207769,-0.215278159,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000105552","BCAT2",19,49298319,49314286,-1,"protein_coding",587,"BCAT2",{"v":1.71339042998067E-11,"d":"1.71E-11"},-0.850643193,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000087076","HSD17B14",19,49316274,49339935,-1,"protein_coding",51171,"HSD17B14",1.37252498082087E-3,0.796635241,0,0,1,{"v":5.80394e-05,"d":"5.80E-05"},{"v":6.82183e-12,"d":"6.82E-12"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.2e-08,"d":"6.20E-08"},"rs36013629;rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000087088","BAX",19,49458072,49465055,1,"protein_coding",581,"BAX",0.167938540925625,"NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000087086","FTL",19,49468558,49470135,1,"protein_coding",2512,"FTL",0.000458652707063046,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000104812","GYS1",19,49471382,49496567,-1,"protein_coding",2997,"GYS1",0.00832267410134216,-0.427100909,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000183207","RUVBL2",19,49496705,49519252,1,"protein_coding",10856,"RUVBL2",0.999110080217839,1.176884172,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000104826","LHB",19,49519237,49520338,-1,"protein_coding",3972,"LHB",0.065600109491978,0.574913604,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.6e-09,"d":"5.60E-09"},"rs8111874",47]
["ENSG00000267335","CTB-60B18.6",19,49526210,49540152,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.3E-9,"d":"7.30E-09"},"rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000104818","CGB2",19,49535169,49536495,1,"protein_coding",114336,"CGB2",0.0694219778865575,0.025765237,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.3E-9,"d":"7.30E-09"},"rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000221916","C19orf73",19,49621655,49622397,-1,"protein_coding",55150,"C19orf73",0.48401312075747,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000177380","PPFIA3",19,49622646,49654283,1,"protein_coding",8541,"PPFIA3",0.99999959495107,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000063127","SLC6A16",19,49792895,49828482,-1,"protein_coding",28968,"SLC6A16",{"v":4.47639511693954e-11,"d":"4.48E-11"},-0.803886516,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000104872","PIH1D1",19,49949555,49956754,-1,"protein_coding",55011,"PIH1D1",0.087951252701366,0.323376102,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000161618","ALDH16A1",19,49956426,49974305,1,"protein_coding",126133,"ALDH16A1",{"v":1.35194745543971e-07,"d":"1.35E-07"},0.132278749,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000142541","RPL13A",19,49990811,49995565,1,"protein_coding",23521,"RPL13A",0.633828368843267,0.703415176,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000142534","RPS11",19,49999622,50002946,1,"protein_coding",6205,"RPS11",0.913344861476602,-0.285364057,0,0,111,{"v":1.68917E-10,"d":"1.69E-10"},{"v":1.11567E-23,"d":"1.12E-23"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-8,"d":"1.20E-08"},"rs59774409;rs36013629;rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000268000","hsa-mir-150",19,50003781,50004614,1,"protein_coding","NA","NA","NA","NA",1,0.345,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":4.9e-08,"d":"4.90E-08"},"rs59774409;rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000104870","FCGRT",19,50010073,50029590,1,"protein_coding",2217,"FCGRT",0.825587179671645,-0.630530045,56,11.58,111,{"v":9.5205e-17,"d":"9.52E-17"},{"v":2.30313e-12,"d":"2.30E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-8,"d":"1.20E-08"},"rs59774409;rs36013629;rs8111874:rs59774409:rs36013629",1.9916666666666665]
["ENSG00000142552","RCN3",19,50030875,50050219,1,"protein_coding",57333,"RCN3",{"v":1.77726445447237E-9,"d":"1.78E-09"},-0.511517783,123,25.3,109,{"v":1.56035e-31,"d":"1.56E-31"},{"v":1.2424e-25,"d":"1.24E-25"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.2E-8,"d":"1.20E-08"},"rs59774409;rs36013629;rs59774409:rs36013629",48]
["ENSG00000142546","NOSIP",19,50058968,50093519,-1,"protein_coding",51070,"NOSIP",0.00230156568092138,-0.458734704,14,8.226,0,"NA","NA","NA","NA","No","NA",{"v":2.1E-7,"d":"2.10E-07"},"rs59774409;rs36013629",48]
["ENSG00000126460","PRRG2",19,50083903,50094272,1,"protein_coding",5639,"PRRG2",{"v":5.96505604158473E-5,"d":"5.97E-05"},-0.030773185,0,0,2,{"v":4.84691E-6,"d":"4.85E-06"},{"v":3.95284e-09,"d":"3.95E-09"},"GTEx/v8/Liver","+","No","NA",{"v":4.9e-08,"d":"4.90E-08"},"rs36013629",48]
["ENSG00000126464","PRR12",19,50094900,50129696,1,"protein_coding",57479,"PRR12",0.999969576883676,"NA",0,0,4,{"v":8.63635e-11,"d":"8.64E-11"},{"v":2.16198e-19,"d":"2.16E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","No","NA",{"v":4.9e-08,"d":"4.90E-08"},"rs36013629",48]
["ENSG00000126458","RRAS",19,50138549,50143458,-1,"protein_coding",6237,"RRAS",0.287257428796457,-0.530932413,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":4.9e-08,"d":"4.90E-08"},"rs59774409:rs36013629:rs8111874",1.9916666666666665]
["ENSG00000126461","SCAF1",19,50145382,50161899,1,"protein_coding",58506,"SCAF1",0.998787538768532,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":4.9e-08,"d":"4.90E-08"},"rs59774409:rs36013629:rs8111874",1.9916666666666665]
["ENSG00000126457","PRMT1",19,50179043,50192286,1,"protein_coding",3276,"PRMT1",0.993587786937211,-0.276977945,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000169169","CPT1C",19,50194155,50216988,1,"protein_coding",126129,"CPT1C",0.0002846277169503,-0.155830562,0,0,5,{"v":2.63762E-5,"d":"2.64E-05"},{"v":5.93031e-08,"d":"5.93E-08"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":1.2E-5,"d":"1.20E-05"},"rs59774409",48]
["ENSG00000126467","TSKS",19,50243010,50266587,-1,"protein_coding",60385,"TSKS",0.980813772290248,-0.204731972,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000196961","AP2A1",19,50270225,50310370,1,"protein_coding",160,"AP2A1",0.9998472799622,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000039650","PNKP",19,50364461,50371166,-1,"protein_coding",11284,"PNKP",{"v":2.8844490761323e-07,"d":"2.88E-07"},0.180578716,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs59774409:rs36013629",48]
["ENSG00000198646","NCOA6",20,33284722,33413452,-1,"protein_coding",23054,"NCOA6",0.990815417122809,-0.852306051,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000078804","TP53INP2",20,33292094,33301243,1,"protein_coding",58476,"TP53INP2",0.341454389532318,-2.209102226,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000131067","GGT7",20,33432523,33460663,-1,"protein_coding",2686,"GGT7",0.998200259468736,-0.466160926,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000131069","ACSS2",20,33459949,33515769,1,"protein_coding",55902,"ACSS2",{"v":8.97239307211796e-11,"d":"8.97E-11"},-0.504093957,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":8.1e-08,"d":"8.10E-08"},"rs2378390",49]
["ENSG00000078814","MYH7B",20,33563206,33590240,1,"protein_coding",57644,"MYH7B",{"v":1.33080887914663E-23,"d":"1.33E-23"},0.056785336,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000100991","TRPC4AP",20,33590207,33680674,-1,"protein_coding",26133,"TRPC4AP",0.999538656142253,0.007918921,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.1e-06,"d":"2.10E-06"},"rs2378390",49]
["ENSG00000088298","EDEM2",20,33703167,33865928,-1,"protein_coding",55741,"EDEM2",0.000137533138342907,-0.173488786,0,0,41,{"v":5.093e-06,"d":"5.09E-06"},{"v":1.1604e-15,"d":"1.16E-15"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","IMR90",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000101000","PROCR",20,33759876,33765165,1,"protein_coding",10544,"PROCR",0.0101308888898987,-0.393625919,0,0,33,{"v":9.4446e-05,"d":"9.44E-05"},{"v":2.24902e-25,"d":"2.25E-25"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.6e-08,"d":"5.60E-08"},"rs2378390",49]
["ENSG00000125966","MMP24",20,33814457,33864801,1,"protein_coding",10893,"MMP24",0.0287623289506785,-0.485751474,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000242372","EIF6",20,33866714,33872788,-1,"protein_coding",3692,"EIF6",0.781942924365479,-0.028008437,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000125998","FAM83C",20,33873534,33880204,-1,"protein_coding",128876,"FAM83C",{"v":3.49242479222024E-5,"d":"3.49E-05"},0.230701112,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.1e-06,"d":"2.10E-06"},"rs2378390",49]
["ENSG00000101019","UQCC1",20,33890369,33999944,-1,"protein_coding",55245,"UQCC1",0.00485442531990324,-0.818063366,0,0,19,{"v":2.58274e-05,"d":"2.58E-05"},{"v":2.28438e-19,"d":"2.28E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7e-08,"d":"7.00E-08"},"rs2378390",49]
["ENSG00000125965","GDF5",20,34021145,34042568,-1,"protein_coding",8200,"GDF5",0.923194898928876,0.072736153,2,5.975,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000126001","CEP250",20,34042985,34099804,1,"protein_coding",11190,"CEP250",{"v":8.25125524749097e-17,"d":"8.25E-17"},-0.898375889,14,15.49,2,{"v":2.21568e-07,"d":"2.22E-07"},{"v":1.15239e-08,"d":"1.15E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000125975","C20orf173",20,34111014,34117481,-1,"protein_coding",140873,"C20orf173","NA",-0.017046168,22,7.783,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000125991","ERGIC3",20,34129770,34145405,1,"protein_coding",51614,"ERGIC3",0.0038590767192969,-0.537742885,36,11.27,55,{"v":1.25435e-05,"d":"1.25E-05"},0.00650288,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.7E-8,"d":"2.70E-08"},"rs2378390",49]
["ENSG00000061656","SPAG4",20,34203814,34208971,1,"protein_coding",6676,"SPAG4",0.110567923366472,-0.441954464,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000214078","CPNE1",20,34213953,34252878,-1,"protein_coding",8904,"CPNE1",{"v":3.87095095726686e-07,"d":"3.87E-07"},"NA",0,0,56,{"v":2.57501e-71,"d":"2.58E-71"},{"v":6.32869e-144,"d":"6.33E-144"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000272897","RP1-309K20.6",20,34220262,34262466,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000244462","RBM12",20,34236847,34252878,-1,"protein_coding",10137,"RBM12",0.474673920574839,-0.297433929,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000244005","NFS1",20,34255977,34287281,-1,"protein_coding",9054,"NFS1",0.832120909457389,-0.782190672,0,0,1,1.15992E-4,0.0344117,"GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000125995","ROMO1",20,34287194,34288906,1,"protein_coding",140823,"ROMO1",0.726806954057013,-0.303915371,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000131051","RBM39",20,34291531,34330234,-1,"protein_coding",9584,"RBM39",0.9999969154952,-0.857805175,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":8.1e-08,"d":"8.10E-08"},"rs2378390",49]
["ENSG00000025293","PHF20",20,34359896,34538303,1,"protein_coding",51230,"PHF20",0.975739227580779,-0.31477599,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":8.1e-08,"d":"8.10E-08"},"rs2378390",49]
["ENSG00000171222","SCAND1",20,34541539,34547394,-1,"protein_coding",51282,"SCAND1",0.158311342081053,-1.080083136,0,0,1,{"v":1.33542e-08,"d":"1.34E-08"},{"v":4.83704e-16,"d":"4.84E-16"},"GTEx/v8/Artery_Aorta","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.7E-8,"d":"2.70E-08"},"rs2378390",49]
["ENSG00000149646","CNBD2",20,34556512,34618622,1,"protein_coding",140894,"CNBD2",{"v":2.29296795546672e-07,"d":"2.29E-07"},-0.003103386,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs2378390",49]
["ENSG00000088367","EPB41L1",20,34679426,34820721,1,"protein_coding",2036,"EPB41L1",0.645386132721516,-0.629643623,0,0,1,{"v":5.84572e-06,"d":"5.85E-06"},{"v":1.69076E-23,"d":"1.69E-23"},"GTEx/v8/Artery_Tibial","-","Yes","Left_Ventricle",{"v":1.9E-6,"d":"1.90E-06"},"rs2378390",49]
["ENSG00000269650","AL121895.1",20,34756461,34758180,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.7E-6,"d":"2.70E-06"},"rs2378390",49]
["ENSG00000101084","C20orf24",20,35234137,35240960,1,"protein_coding",55969,"C20orf24",0.856745481043852,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.1e-08,"d":"8.10E-08"},"rs2378390",49]
["ENSG00000101342","TLDC2",20,35504524,35522638,1,"protein_coding",140711,"TLDC2",0.113178686310675,-0.852968274,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.1e-08,"d":"8.10E-08"},"rs2378390",49]
["ENSG00000170471","RALGAPB",20,37101459,37207504,1,"protein_coding",57148,"RALGAPB",0.999999955632558,-1.599770985,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.4e-07,"d":"3.40E-07"},"rs2179372",51]
["ENSG00000101442","ACTR5",20,37377085,37400834,1,"protein_coding",79913,"ACTR5",{"v":1.00014232070039E-12,"d":"1.00E-12"},0.539172179,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-12,"d":"7.00E-12"},"rs2179372:rs1883711",2.11875]
["ENSG00000101452","DHX35",20,37590942,37668366,1,"protein_coding",60625,"DHX35",{"v":9.69273790916275e-11,"d":"9.69E-11"},-0.629421294,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000204103","MAFB",20,39314488,39317880,-1,"protein_coding",9935,"MAFB","NA",-1.167100522,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6E-14,"d":"4.60E-14"},"rs1883711:rs151290120:rs2179372",2.11875]
["ENSG00000198900","TOP1",20,39657458,39753127,1,"protein_coding",7150,"TOP1",0.999999399962319,-1.244368761,14,6.727,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000124181","PLCG1",20,39765600,39811629,1,"protein_coding",5335,"PLCG1",0.76335235197211,"NA",14,22.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Hippocampus:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000174306","ZHX3",20,39807088,39946312,-1,"protein_coding",23051,"ZHX3",0.354421202947907,-2.86061457,63,22.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000132793","LPIN3",20,39969560,39989222,1,"protein_coding",64900,"LPIN3",{"v":4.43532236084843e-11,"d":"4.44E-11"},1.280780073,1,3.264,79,{"v":6.72024e-18,"d":"6.72E-18"},{"v":1.60147e-33,"d":"1.60E-33"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000183798","EMILIN3",20,39988606,39995467,-1,"protein_coding",90187,"EMILIN3",0.00139809720973059,0.56095672,0,0,75,{"v":3.02111E-6,"d":"3.02E-06"},{"v":7.35136E-5,"d":"7.35E-05"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Liver","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000124177","CHD6",20,40030741,40247133,-1,"protein_coding",84181,"CHD6",0.99999999999754,-0.875165314,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.8e-07,"d":"2.80E-07"},"rs2179372",51]
["ENSG00000196090","PTPRT",20,40701392,41818610,-1,"protein_coding",11122,"PTPRT",0.999998893194682,2.656289086,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.3e-08,"d":"4.30E-08"},"rs2179372",51]
["ENSG00000124193","SRSF6",20,42086568,42092245,1,"protein_coding",6431,"SRSF6",0.992976413171211,-0.317719212,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm",{"v":4.3e-08,"d":"4.30E-08"},"rs2179372",51]
["ENSG00000185513","L3MBTL1",20,42136320,42179590,1,"protein_coding",26013,"L3MBTL1",{"v":2.0785493269036e-07,"d":"2.08E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.4e-07,"d":"3.40E-07"},"rs2179372",51]
["ENSG00000101049","SGK2",20,42187608,42216877,1,"protein_coding",10110,"SGK2",{"v":2.93457296557479e-07,"d":"2.93E-07"},0.613864962,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.9e-08,"d":"2.90E-08"},"rs2179372",51]
["ENSG00000157600","TMEM164",23,109245859,109425962,1,"protein_coding",84187,"TMEM164",0.877400449225457,-2.007872381,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7e-10,"d":"1.70E-10"},"rs372038686",52]
["ENSG00000101935","AMMECR1",23,109437414,109683461,-1,"protein_coding",9949,"AMMECR1",0.910792997313756,-2.109243506,7,13.98,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.7e-10,"d":"1.70E-10"},"rs372038686",52]
["ENSG00000243978","RGAG1",23,109602044,109699562,1,"protein_coding",57529,"RGAG1",0.912655333274139,0.494918933,22,13.98,376,{"v":3.01409e-06,"d":"3.01E-06"},0.00335742,"GTEx/v8/Heart_Atrial_Appendage","-","No","NA",{"v":1.6e-10,"d":"1.60E-10"},"rs372038686",52]
["ENSG00000101938","CHRDL1",23,109917084,110039286,-1,"protein_coding",91851,"CHRDL1",0.0536284936083553,"NA",77,16.15,392,{"v":7.97604e-50,"d":"7.98E-50"},{"v":1.32344E-42,"d":"1.32E-42"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","No","NA",{"v":1.6e-10,"d":"1.60E-10"},"rs372038686",52]
["ENSG00000077279","DCX",23,110537007,110655603,-1,"protein_coding",1641,"DCX",0.863196407367064,-3.566269335,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.2e-08,"d":"2.20E-08"},"rs372038686",52]
["ENSG00000187823","ZCCHC16",23,111697727,111700473,1,"protein_coding",340595,"ZCCHC16",0.000561724706329207,1.180700486,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-10,"d":"1.70E-10"},"rs372038686",52]

{"sheet":"ST4D","index":7,"n_rows":1187,"n_cols":23,"rows_kept":1187}
["ensg","symbol","chr","start","end","strand","type","entrezID","HUGO","pLI","ncRVIS","posMapSNPs","posMapMaxCADD","eqtlMapSNPs","eqtlMapminP","eqtlMapminQ","eqtlMapts","eqtlDirection","ciMap","ciMapts","minGwasP","IndSigSNPs","GenomicLocus"]
["ENSG00000173372","C1QA",1,22962999,22966101,1,"protein_coding",712,"C1QA",0.0497899792321254,0.221836438,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.8e-09,"d":"2.80E-09"},"rs375390883:1:23747996_GA_G",1]
["ENSG00000159189","C1QC",1,22970123,22974603,1,"protein_coding",714,"C1QC",0.0173819025149602,0.719487547,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.8e-09,"d":"2.80E-09"},"rs375390883:1:23747996_GA_G",1]
["ENSG00000173369","C1QB",1,22979255,22988031,1,"protein_coding",713,"C1QB",0.0858810485832231,0.026532976,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.8e-09,"d":"2.80E-09"},"rs375390883:1:23747996_GA_G",1]
["ENSG00000125944","HNRNPR",1,23630264,23670829,-1,"protein_coding",10236,"HNRNPR",0.999079074304417,-0.733548061,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-09,"d":"2.30E-09"},"1:23747996_GA_G:rs375390883",1]
["ENSG00000125945","ZNF436",1,23685941,23695935,-1,"protein_coding",80818,"ZNF436",0.304488387158864,-0.229845222,0,0,21,{"v":9.86385E-7,"d":"9.86E-07"},{"v":3.86751e-44,"d":"3.87E-44"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","IMR90",{"v":1.2E-10,"d":"1.20E-10"},"rs375390883;rs375390883:1:23747996_GA_G",1]
["ENSG00000249087","C1orf213",1,23695490,23698332,1,"protein_coding",148898,"C1orf213",2.60771141851481E-4,"NA",0,0,21,{"v":2.56657e-07,"d":"2.57E-07"},{"v":4.16168e-42,"d":"4.16E-42"},"GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","-","Yes","IMR90",{"v":1.2E-10,"d":"1.20E-10"},"rs375390883;rs375390883:1:23747996_GA_G",1]
["ENSG00000204219","TCEA3",1,23707554,23751233,-1,"protein_coding",6920,"TCEA3",0.000965885853095805,"NA",25,17.11,61,{"v":1.56531e-11,"d":"1.57E-11"},{"v":1.85952e-17,"d":"1.86E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","IMR90",{"v":1.2E-10,"d":"1.20E-10"},"1:23747996_GA_G;rs375390883;rs375390883:1:23747996_GA_G",1]
["ENSG00000088280","ASAP3",1,23755056,23811061,-1,"protein_coding",55616,"ASAP3",{"v":2.35907220968951e-10,"d":"2.36E-10"},-0.119098762,71,17.11,67,{"v":1.83221E-29,"d":"1.83E-29"},{"v":1.28343E-23,"d":"1.28E-23"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:IMR90",{"v":1.2E-10,"d":"1.20E-10"},"rs375390883;1:23747996_GA_G;rs375390883:1:23747996_GA_G",1]
["ENSG00000007968","E2F2",1,23832922,23857712,-1,"protein_coding",1870,"E2F2",0.914702778499156,-0.034311204,1,1.595,23,{"v":4.18331e-06,"d":"4.18E-06"},0.00318171,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops:Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-09,"d":"2.30E-09"},"rs375390883;1:23747996_GA_G;rs375390883:1:23747996_GA_G",1]
["ENSG00000117318","ID3",1,23884409,23886285,-1,"protein_coding",3399,"ID3",0.68879433753555,-0.270653991,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.8e-09,"d":"2.80E-09"},"rs375390883:rs2986164:1:23747996_GA_G","01:02:00"]
["ENSG00000197880","MDS2",1,23907985,23967058,1,"protein_coding",259283,"MDS2",0.0429655728784688,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.8e-09,"d":"2.80E-09"},"rs2986164:rs375390883:1:23747996_GA_G","01:02:00"]
["ENSG00000142676","RPL11",1,24018269,24022915,1,"protein_coding",6135,"RPL11",0.725843320629066,0.111094014,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.2E-10,"d":"1.20E-10"},"rs375390883:1:23747996_GA_G",1]
["ENSG00000057757","PITHD1",1,24104895,24114722,1,"protein_coding",57095,"PITHD1",0.102416722752494,-0.424805415,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell",{"v":2.8e-09,"d":"2.80E-09"},"rs375390883:1:23747996_GA_G",1]
["ENSG00000011009","LYPLA2",1,24117460,24122029,1,"protein_coding",11313,"LYPLA2",0.979519145027567,-0.992130873,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:Mesenchymal_Stem_Cell",{"v":2.8e-09,"d":"2.80E-09"},"rs375390883:1:23747996_GA_G",1]
["ENSG00000117602","RCAN3",1,24829387,24867530,1,"protein_coding",11123,"RCAN3",0.00320642195331169,1.106938656,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3.1E-7,"d":"3.10E-07"},"rs2986164",2]
["ENSG00000133226","SRRM1",1,24958207,24999758,1,"protein_coding",10250,"SRRM1",0.999999022390233,-0.322831857,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.1E-7,"d":"2.10E-07"},"rs2986164",2]
["ENSG00000169504","CLIC4",1,25071848,25170815,1,"protein_coding",25932,"CLIC4",0.00946200366501209,-1.236427948,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-07,"d":"3.20E-07"},"rs2986164",2]
["ENSG00000117614","SYF2",1,25549170,25558993,-1,"protein_coding",25949,"SYF2",0.0379270965280319,-0.019645579,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":2.1E-7,"d":"2.10E-07"},"rs2986164",2]
["ENSG00000117616","C1orf63",1,25568728,25664704,-1,"protein_coding",57035,"C1orf63",{"v":2.72287500037132e-08,"d":"2.72E-08"},-0.47340473,10,6.636,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs2986164",2]
["ENSG00000187010","RHD",1,25598884,25656936,1,"protein_coding",6007,"RHD",0.00606009991775824,0.419810588,5,6.636,176,{"v":6.63088e-50,"d":"6.63E-50"},{"v":4.59706e-106,"d":"4.60E-106"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":1.4E-8,"d":"1.40E-08"},"rs2986164",2]
["ENSG00000183726","TMEM50A",1,25664408,25688852,1,"protein_coding",23585,"TMEM50A",0.333486481175581,-0.802493983,16,9.801,176,{"v":6.66978e-13,"d":"6.67E-13"},{"v":3.27318e-22,"d":"3.27E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000188672","RHCE",1,25688740,25756683,-1,"protein_coding",6006,"RHCE",0.861454126246099,0.078594887,90,13.31,176,{"v":5.93595e-36,"d":"5.94E-36"},{"v":1.30902E-29,"d":"1.31E-29"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000204178","TMEM57",1,25757388,25826700,1,"protein_coding",55219,"TMEM57",0.992504411290221,1.055454968,114,15.98,176,{"v":8.27856e-16,"d":"8.28E-16"},{"v":2.13504e-11,"d":"2.14E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000157978","LDLRAP1",1,25870071,25895377,1,"protein_coding",26119,"LDLRAP1",{"v":2.90076895064709e-05,"d":"2.90E-05"},-0.605728099,2,2.099,1,{"v":4.80051e-05,"d":"4.80E-05"},{"v":2.7201e-11,"d":"2.72E-11"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000117643","MAN1C1",1,25943959,26112698,1,"protein_coding",57134,"MAN1C1",0.0490480402547963,0.898505667,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-07,"d":"2.50E-07"},"rs2986164",2]
["ENSG00000162430","SEPN1",1,26126667,26144713,1,"protein_coding",57190,"SEPN1",{"v":1.08497392205754e-07,"d":"1.08E-07"},-0.14036306,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000255054","RP1-317E23.6",1,26137961,26150235,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000117640","MTFR1L",1,26145131,26159432,1,"protein_coding",56181,"MTFR1L",0.431750877541367,0.035573706,0,0,14,{"v":3.11664E-5,"d":"3.12E-05"},{"v":1.5749E-37,"d":"1.57E-37"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000223474","AL020996.1",1,26145212,26147288,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000127423","AUNIP",1,26158414,26185903,-1,"protein_coding",79000,"AUNIP",{"v":5.49329871865606E-8,"d":"5.49E-08"},0.668522621,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-8,"d":"1.40E-08"},"rs2986164",2]
["ENSG00000182749","PAQR7",1,26187701,26197744,-1,"protein_coding",164091,"PAQR7",0.0093107679780527,0.742661414,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.5e-07,"d":"2.50E-07"},"rs2986164",2]
["ENSG00000117632","STMN1",1,26210672,26233482,-1,"protein_coding",3925,"STMN1",0.648591503545553,-0.336099456,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":1.9e-07,"d":"1.90E-07"},"rs2986164",2]
["ENSG00000158006","PAFAH2",1,26286258,26324648,-1,"protein_coding",5051,"PAFAH2",{"v":2.68539651867445e-07,"d":"2.69E-07"},-0.682015872,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs2986164",2]
["ENSG00000158008","EXTL1",1,26346375,26362955,1,"protein_coding",2134,"EXTL1",{"v":1.17897567862766E-12,"d":"1.18E-12"},-0.545045167,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-07,"d":"2.50E-07"},"rs2986164",2]
["ENSG00000197245","FAM110D",1,26485511,26489119,1,"protein_coding",79927,"FAM110D",0.550404227081523,-0.050060073,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.3e-07,"d":"5.30E-07"},"rs2986164",2]
["ENSG00000142675","CNKSR1",1,26503894,26516377,1,"protein_coding",10256,"CNKSR1",{"v":3.79048704121579e-16,"d":"3.79E-16"},-0.156165951,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.4e-06,"d":"3.40E-06"},"rs2986164",2]
["ENSG00000130695","CEP85",1,26560691,26605299,1,"protein_coding",64793,"CEP85",0.00585126875456993,-0.28245067,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.2e-06,"d":"1.20E-06"},"rs2986164",2]
["ENSG00000142669","SH3BGRL3",1,26605667,26608007,1,"protein_coding",83442,"SH3BGRL3",0.795103829065415,-0.629466622,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3.1E-7,"d":"3.10E-07"},"rs2986164",2]
["ENSG00000116209","TMEM59",1,54497347,54519177,-1,"protein_coding",9528,"TMEM59",{"v":2.23025067852854E-7,"d":"2.23E-07"},0.206649282,0,0,1,{"v":2.03947E-5,"d":"2.04E-05"},1.96452E-3,"GTEx/v8/Artery_Aorta","+","No","NA",{"v":3.3E-27,"d":"3.30E-27"},"rs11591147",3]
["ENSG00000169174","PCSK9",1,55505221,55530525,1,"protein_coding",255738,"PCSK9",{"v":1.02507611210468E-10,"d":"1.03E-10"},0.264270736,5,15.41,7,{"v":2.27824e-14,"d":"2.28E-14"},{"v":8.14778E-23,"d":"8.15E-23"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial","+","No","NA",{"v":3.3E-27,"d":"3.30E-27"},"rs11206510;rs11591147;rs12067569;rs34232196",3]
["ENSG00000162402","USP24",1,55532032,55680786,-1,"protein_coding",23358,"USP24",0.999999998496473,-1.006094649,28,15.23,2,{"v":9.28051e-05,"d":"9.28E-05"},{"v":2.70552E-9,"d":"2.71E-09"},"GTEx/v8/Artery_Tibial","-","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs12067569;rs12750160;rs12067569:rs12750160",3]
["ENSG00000162407","PPAP2B",1,56960419,57110974,-1,"protein_coding",8613,"PPAP2B",0.961834123262929,-0.049380558,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs12067569:rs12750160",3]
["ENSG00000162409","PRKAA2",1,57110995,57181008,1,"protein_coding",5563,"PRKAA2",{"v":1.44261719898224E-5,"d":"1.44E-05"},-1.053997381,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs12067569:rs12750160",3]
["ENSG00000187889","C1orf168",1,57184477,57285369,-1,"protein_coding",199920,"C1orf168",{"v":2.35652055532321e-30,"d":"2.36E-30"},-0.300645978,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs12067569:rs12750160",3]
["ENSG00000157131","C8A",1,57320479,57383894,1,"protein_coding",731,"C8A",{"v":5.355640730752E-11,"d":"5.36E-11"},0.184569853,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs12067569:rs12750160",3]
["ENSG00000021852","C8B",1,57394883,57431813,-1,"protein_coding",732,"C8B",{"v":1.49406934497858E-9,"d":"1.49E-09"},0.183539069,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs12067569:rs12750160",3]
["ENSG00000134709","HOOK1",1,60280458,60342050,1,"protein_coding",51361,"HOOK1",{"v":4.15670073195207e-05,"d":"4.16E-05"},-0.06279745,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":7e-103,"d":"7.00E-103"},"1:62980399_CACA_C:rs1183851;rs1168100:rs912540;rs536629310:1:62980399_CACA_C;rs6661669:1:63179919_AAG_A:1:63183414_CCA_C:rs149511741:rs76272805:rs61775882:rs578078376:rs10458569:rs77449055:rs373836691:rs1183851",4]
["ENSG00000134716","CYP2J2",1,60358980,60392462,-1,"protein_coding",1573,"CYP2J2",{"v":4.51201698997771e-12,"d":"4.51E-12"},0.320327764,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.9e-16,"d":"6.90E-16"},"rs7518009:rs35837000:rs76272805:rs6587973:rs138704976:1:63179919_AAG_A",4]
["ENSG00000162599","NFIA",1,61330931,61928465,1,"protein_coding",4774,"NFIA",0.999555166212873,-0.180372327,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":8.7e-21,"d":"8.70E-21"},"rs6587973:rs12044009:rs371337535:rs138704976:rs72929768:rs77449055",4]
["ENSG00000132854","KANK4",1,62702651,62785085,-1,"protein_coding",163782,"KANK4",{"v":5.3984986278488e-08,"d":"5.40E-08"},-0.458433659,0,0,2,{"v":1.23552E-5,"d":"1.24E-05"},{"v":9.06934e-05,"d":"9.07E-05"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-21,"d":"8.70E-21"},"rs72929768;rs7518009:rs35837000:rs76272805:rs6587973:rs138704976:1:63179919_AAG_A:rs12044009:rs371337535:rs72929768",4]
["ENSG00000162607","USP1",1,62901968,62917475,1,"protein_coding",7398,"USP1",0.993180568281562,-1.542076225,57,18.26,10,{"v":1.97043E-7,"d":"1.97E-07"},4.32786E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.7e-103,"d":"6.70E-103"},"1:63183414_CCA_C;1:62980399_CACA_C;rs6661669;rs1183851;rs578078376;1:63179919_AAG_A;rs149511741;rs912540;rs536629310;rs10458569;rs72929768;rs1168100;rs2149116;rs12409274:rs35332757;rs7512480:rs549889612:1:62980399_CACA_C;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs1183851;rs1168100:1:63179919_AAG_A:rs149511741:rs76272805:rs61775882:rs374131620:rs1183851;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs12044009:rs12122434:1:63268136_TA_T:rs35332757:1:63045366_GA_G",4]
["ENSG00000116641","DOCK7",1,62920399,63153969,-1,"protein_coding",85440,"DOCK7",0.771361085896655,"NA",335,18.64,561,{"v":1.09201E-20,"d":"1.09E-20"},{"v":9.93875E-16,"d":"9.94E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.7E-103,"d":"1.70E-103"},"1:63179919_AAG_A;1:62980399_CACA_C;rs6661669;rs149511741;rs578078376;rs912540;rs536629310;rs10458569;1:63183414_CCA_C;rs77449055;rs373836691;rs1183851;rs55853774;rs61775882;rs17381383;rs1168100;rs76272805;1:63045366_GA_G;rs12044009;1:63130453_TA_T;1:63131385_CAA_C;1:63134595_CA_C;1:63149883_TA_T;rs183409343;1:63203399_AT_A;rs72929768;rs2149116;rs12409274;rs11809792;rs61765938;rs35332757;rs7512480;rs12122434;1:63190449_GTTTTTTTT_G:rs912540:1:63203399_AT_A:rs6661669:rs2149116:1:62980399_CACA_C;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs76272805:1:63045366_GA_G:rs12044009:1:63179919_AAG_A:rs1183851;rs1168100:rs149511741:rs61775882",4]
["ENSG00000132855","ANGPTL3",1,63063158,63071830,1,"protein_coding",27329,"ANGPTL3",{"v":2.12015609401708e-07,"d":"2.12E-07"},-0.803837249,20,12.12,15,{"v":1.13102e-05,"d":"1.13E-05"},0.0421505,"GTEx/v8/Liver","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7E-103,"d":"1.70E-103"},"1:63183414_CCA_C;1:62980399_CACA_C;rs12044009;1:63179919_AAG_A;rs6661669;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs1183851;rs1168100:1:63179919_AAG_A:rs149511741:rs76272805:rs61775882:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs536629310:rs17381383:rs1168100:rs55853774:1:63130453_TA_T:1:63131385_CAA_C:1:63134595_CA_C:1:63149883_TA_T:rs183409343:rs72929768:rs116316096:rs912540;1:63203399_AT_A:rs12409274:rs35332757:rs11809792:rs61765938:rs35332757;rs7512480:rs12044009:rs549889612:rs12122434:1:63268136_TA_T:rs35332757;rs12409274;rs7512480:rs7512480",4]
["ENSG00000269624","AL138847.1",1,63073437,63075249,1,"protein_coding","NA","NA","NA","NA",14,12.12,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7E-103,"d":"1.70E-103"},"1:63179919_AAG_A;1:62980399_CACA_C;rs12044009;rs1183851;rs1168100;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs1183851;rs1168100:1:63179919_AAG_A:rs149511741:rs76272805:rs61775882:rs374131620:rs1183851;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs536629310:rs17381383:rs1168100:rs55853774:1:63130453_TA_T:1:63131385_CAA_C:1:63134595_CA_C:1:63149883_TA_T:rs183409343:rs72929768:rs116316096:rs912540;1:63203399_AT_A:rs12409274:rs35332757:rs11809792:rs61765938:rs35332757;rs7512480:rs12044009:rs549889612:rs12122434:1:63268136_TA_T:rs35332757;rs12409274;rs7512480:rs7512480",4]
["ENSG00000125703","ATG4C",1,63249806,63331184,1,"protein_coding",84938,"ATG4C",{"v":3.32761781234443e-09,"d":"3.33E-09"},-0.809376853,170,17.7,150,{"v":6.89586e-06,"d":"6.90E-06"},0.00836476,"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7E-103,"d":"1.70E-103"},"rs12409274;rs12044009;rs35332757;rs7512480;rs549889612;rs12122434;1:63268136_TA_T;rs11809792;rs61765938;rs77449055;1:62980399_CACA_C:1:62980399_CACA_C;rs6661669:rs1183851:rs578078376:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs373836691:rs72929768:rs116316096:1:63179919_AAG_A:rs149511741:rs536629310:rs17381383:rs1168100:rs76272805:1:63045366_GA_G:rs12044009:rs1183851;rs1168100:rs61775882:rs55853774:rs912540",4]
["ENSG00000187140","FOXD3",1,63788730,63790797,1,"protein_coding",27022,"FOXD3","NA",-0.433105976,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8E-7,"d":"1.80E-07"},"rs77449055",4]
["ENSG00000088035","ALG6",1,63833261,63904233,1,"protein_coding",29929,"ALG6",0.0553676261725129,-0.307102505,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1e-26,"d":"3.10E-26"},"rs77449055:rs35332757;rs7512480:rs11809792:rs12409274:rs35332757:rs7512480",4]
["ENSG00000142856","ITGB3BP",1,63906441,64059392,-1,"protein_coding",23421,"ITGB3BP",{"v":1.47054021720334E-5,"d":"1.47E-05"},-0.391812829,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.8E-7,"d":"1.80E-07"},"rs77449055",4]
["ENSG00000203965","EFCAB7",1,63989043,64038364,1,"protein_coding",84455,"EFCAB7",{"v":1.67071925383672e-12,"d":"1.67E-12"},-0.503488032,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.7E-103,"d":"1.70E-103"},"rs77449055:rs6587973:rs12044009:rs371337535:rs138704976:rs72929768:rs116316096:1:63183414_CCA_C:1:62980399_CACA_C:1:62980399_CACA_C;rs6661669:rs1183851:rs578078376:1:63179919_AAG_A:rs149511741:rs912540;rs536629310:rs10458569:rs373836691:rs35332757;rs7512480:rs11809792:rs12409274:rs61765938:rs35332757:rs35332757;rs12409274;rs7512480:rs7512480:rs76272805:1:63045366_GA_G:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs549889612:rs12122434:1:63268136_TA_T:rs55853774:rs61775882:rs17381383:rs1183851",4]
["ENSG00000116652","DLEU2L",1,64014588,64015405,1,"protein_coding",79469,"DLEU2L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7e-103,"d":"7.00E-103"},"1:62980399_CACA_C;rs6661669:1:62980399_CACA_C:rs912540;rs536629310:rs10458569:1:63183414_CCA_C:rs77449055:rs578078376:rs373836691:rs1183851:rs35332757;rs7512480:rs11809792:rs12409274:rs35332757:rs7512480:rs61765938:rs35332757;rs12409274;rs7512480:rs549889612:rs12044009:rs12122434:1:63268136_TA_T:rs536629310:rs17381383:1:63179919_AAG_A:rs1168100:rs1183851;rs1168100:rs149511741:rs76272805:rs61775882:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116",4]
["ENSG00000079739","PGM1",1,64058947,64125916,1,"protein_coding",5236,"PGM1",{"v":9.96139807231456e-06,"d":"9.96E-06"},1.203178507,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.8E-7,"d":"1.80E-07"},"rs77449055",4]
["ENSG00000158966","CACHD1",1,64936428,65158741,1,"protein_coding",57685,"CACHD1",0.838036969203847,0.056390161,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.8E-7,"d":"1.80E-07"},"rs77449055",4]
["ENSG00000162437","RAVER2",1,65210778,65298915,1,"protein_coding",55225,"RAVER2",{"v":1.85996394365043E-6,"d":"1.86E-06"},-0.746777186,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.7e-103,"d":"6.70E-103"},"1:62980399_CACA_C:1:63183414_CCA_C:rs77449055:rs536629310:rs17381383:rs578078376:1:63179919_AAG_A:rs1168100:rs912540;rs536629310:rs6587973:rs12044009:rs371337535:rs138704976:rs72929768:rs35332757;rs7512480:rs11809792:rs12409274:rs35332757:rs7512480:rs76272805:1:63045366_GA_G:1:62980399_CACA_C;rs6661669:rs374131620:rs1183851;rs1168100;rs2149116:1:63185902_CT_C:rs6661669:1:63203399_AT_A:1:63190449_GTTTTTTTT_G:rs912540:rs2149116:rs61765938:rs35332757;rs12409274;rs7512480",4]
["ENSG00000116675","DNAJC6",1,65713902,65881552,1,"protein_coding",9829,"DNAJC6",0.99918835079312,-0.584518275,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.8E-7,"d":"1.80E-07"},"rs77449055",4]
["ENSG00000143107","FNDC7",1,109255279,109285365,1,"protein_coding",163479,"FNDC7",3.18365257387006E-4,-0.454973515,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6e-06,"d":"1.60E-06"},"rs61799430",5]
["ENSG00000116266","STXBP3",1,109289296,109352148,1,"protein_coding",6814,"STXBP3",{"v":7.39663613294889e-06,"d":"7.40E-06"},-0.348222386,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.6e-06,"d":"1.60E-06"},"rs61799430",5]
["ENSG00000121957","GPSM2",1,109417972,109477167,1,"protein_coding",29899,"GPSM2",{"v":2.9412972070079e-10,"d":"2.94E-10"},0.141117521,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway",{"v":4.9e-11,"d":"4.90E-11"},"rs6657811;rs35271870",5]
["ENSG00000085433","WDR47",1,109512836,109584850,-1,"protein_coding",22911,"WDR47",0.90566161819711,-0.351230971,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":8.4e-12,"d":"8.40E-12"},"rs6657811;rs35271870:rs61799430:rs35271870:rs1337248:rs657420",5]
["ENSG00000197780","TAF13",1,109605108,109618624,-1,"protein_coding",6884,"TAF13",0.0198501953204612,0.249428817,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":8.4e-12,"d":"8.40E-12"},"rs61799430:rs35271870:rs1337248",5]
["ENSG00000215717","TMEM167B",1,109632425,109639556,1,"protein_coding",56900,"TMEM167B",0.632476718728509,-0.038371693,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":8.4e-12,"d":"8.40E-12"},"rs61799430:rs657420:rs35271870:rs1337248",5]
["ENSG00000179902","C1orf194",1,109648573,109656479,-1,"protein_coding",127003,"C1orf194",{"v":2.50029511352176e-07,"d":"2.50E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.4e-12,"d":"8.40E-12"},"rs6657811;rs35271870:rs61799430:rs35271870:rs1337248",5]
["ENSG00000116299","KIAA1324",1,109656301,109749401,1,"protein_coding",57535,"KIAA1324",{"v":2.14864520738644E-8,"d":"2.15E-08"},"NA",2,13.58,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.4e-12,"d":"8.40E-12"},"rs61799430;rs6657811;rs35271870:rs61799430:rs35271870:rs1337248",5]
["ENSG00000031698","SARS",1,109756540,109780791,1,"protein_coding",6301,"SARS",0.999150650957633,-0.332037527,4,13.58,4,{"v":1.359E-6,"d":"1.36E-06"},1.81496E-3,"GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.5e-32,"d":"3.50E-32"},"rs61799430;rs35271870;rs35271870:rs1337248:rs657420:rs61799430:rs3832016:rs611917:rs68104325",5]
["ENSG00000143126","CELSR2",1,109792641,109818372,1,"protein_coding",1952,"CELSR2",0.999999199832348,0.807304437,34,18.47,41,{"v":9.42742e-34,"d":"9.43E-34"},{"v":2.20583e-27,"d":"2.21E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1E-32,"d":"1.10E-32"},"rs61799430;rs1337248;rs6657811;rs35271870;1:109809343_CT_C;rs3832016;rs611917;rs657420;rs68104325;rs61799430:rs35271870:rs3832016:rs611917:rs657420:rs68104325:rs6657811;rs35271870:rs1337248:rs6657811:1:109809343_CT_C",5]
["ENSG00000134222","PSRC1",1,109822178,109825808,-1,"protein_coding",84722,"PSRC1",{"v":1.74717788563073e-06,"d":"1.75E-06"},-0.208880013,29,18.47,37,{"v":1.0541E-37,"d":"1.05E-37"},{"v":1.834e-30,"d":"1.83E-30"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen",{"v":1.1E-32,"d":"1.10E-32"},"rs3832016;rs611917;rs35271870;rs657420;rs68104325;rs61799430;rs6657811;rs1337248:rs61799430:rs35271870",5]
["ENSG00000221986","MYBPHL",1,109834987,109849663,-1,"protein_coding",343263,"MYBPHL",0.00461844098878081,0.281706372,10,12.97,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-13,"d":"1.30E-13"},"rs657420;rs68104325;rs6657811;rs35271870:rs61799430:rs35271870:rs1337248",5]
["ENSG00000134243","SORT1",1,109852192,109940573,-1,"protein_coding",6272,"SORT1",0.999926560036891,-1.346190944,0,0,28,{"v":3.08634e-54,"d":"3.09E-54"},{"v":3.21918e-45,"d":"3.22E-45"},"GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.1E-32,"d":"1.10E-32"},"rs35271870;rs1337248;rs6657811;rs3832016;rs611917;rs68104325;rs61799430:rs1337248:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs35271870:rs3832016:rs611917:rs657420:rs68104325",5]
["ENSG00000143106","PSMA5",1,109941653,109969062,-1,"protein_coding",5686,"PSMA5",0.974255885097096,-1.084093805,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":8.4e-12,"d":"8.40E-12"},"rs61799430:rs35271870:rs1337248:rs657420",5]
["ENSG00000143028","SYPL2",1,110009180,110024759,1,"protein_coding",284612,"SYPL2",0.0167710987562036,0.437866135,0,0,27,{"v":1.20726E-11,"d":"1.21E-11"},{"v":1.41445e-54,"d":"1.41E-54"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver","+","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.1E-32,"d":"1.10E-32"},"rs35271870;rs6657811;rs3832016;rs68104325;rs611917;rs657420;rs61799430:rs657420:rs35271870:rs1337248:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs3832016:rs611917:rs68104325",5]
["ENSG00000162650","ATXN7L2",1,110026101,110035426,1,"protein_coding",127002,"ATXN7L2",0.718954812432385,"NA",0,0,18,{"v":5.83014e-07,"d":"5.83E-07"},{"v":6.65426e-17,"d":"6.65E-17"},"GTEx/v8/Artery_Tibial:GTEx/v8/Liver","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.1E-32,"d":"1.10E-32"},"rs61799430;rs611917;rs3832016;rs657420;rs61799430:rs1337248:rs657420:rs35271870:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs3832016:rs611917:rs68104325",5]
["ENSG00000174151","CYB561D1",1,110036674,110045554,1,"protein_coding",284613,"CYB561D1",0.0158304191038284,-0.395994268,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.1E-32,"d":"1.10E-32"},"rs61799430:rs35271870:rs1337248:rs657420:rs6657811;rs35271870:rs6657811:1:109809343_CT_C:rs3832016:rs611917:rs68104325",5]
["ENSG00000181754","AMIGO1",1,110046797,110052360,-1,"protein_coding",57463,"AMIGO1",0.888492588974354,-0.212526248,0,0,8,{"v":1.84657E-16,"d":"1.85E-16"},{"v":3.62238e-97,"d":"3.62E-97"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":7.7e-16,"d":"7.70E-16"},"rs657420;rs68104325;rs6657811;rs35271870:rs1337248:rs6657811:1:109809343_CT_C:rs61799430:rs35271870",5]
["ENSG00000156097","GPR61",1,110082494,110091028,1,"protein_coding",83873,"GPR61",0.801488898268086,-0.586870154,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7.7e-16,"d":"7.70E-16"},"rs6657811;rs35271870:rs1337248:rs6657811:1:109809343_CT_C:rs61799430:rs35271870",5]
["ENSG00000065135","GNAI3",1,110091233,110136975,1,"protein_coding",2773,"GNAI3",0.038811277618943,0.458884037,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":8.4e-12,"d":"8.40E-12"},"rs61799430:rs35271870:rs1337248",5]
["ENSG00000168765","GSTM4",1,110198703,110208118,1,"protein_coding",2948,"GSTM4",0.000917344712640999,0.373951732,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90",{"v":8.4e-12,"d":"8.40E-12"},"rs61799430:rs657420:rs35271870:rs1337248",5]
["ENSG00000134184","GSTM1",1,110230436,110251661,1,"protein_coding",2944,"GSTM1",0.345713720441091,"NA",0,0,1,1.15821E-4,{"v":3.52619e-16,"d":"3.53E-16"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops",{"v":6.3e-11,"d":"6.30E-11"},"rs35271870;rs1337248",5]
["ENSG00000168710","AHCYL1",1,110527308,110566357,1,"protein_coding",10768,"AHCYL1",0.999795279646545,-1.117324202,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6e-06,"d":"1.60E-06"},"rs61799430",5]
["ENSG00000143674","MLK4",1,233463514,233520894,1,"protein_coding",84451,"MAP3K21",0.000607298684335364,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":3.6e-14,"d":"3.60E-14"},"rs633269:rs199900492",6]
["ENSG00000059588","TARBP1",1,234527059,234614849,-1,"protein_coding",6894,"TARBP1",{"v":5.69518410914162e-16,"d":"5.70E-16"},0.440309518,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.6e-14,"d":"3.60E-14"},"rs633269:rs199900492",6]
["ENSG00000168264","IRF2BP2",1,234740015,234745271,-1,"protein_coding",359948,"IRF2BP2",0.470291318540817,-0.545562654,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Adrenal:Aorta:Bladder:Dorsolateral_Prefrontal_Cortex:Hippocampus:Left_Ventricle:Liver:Lung:Pancreas:Psoas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.6e-14,"d":"3.60E-14"},"rs633269:rs199900492",6]
["ENSG00000173726","TOMM20",1,235272651,235292251,-1,"protein_coding",9804,"TOMM20",0.577780758415904,-1.79497007,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":3.6e-14,"d":"3.60E-14"},"rs633269:rs199900492",6]
["ENSG00000188739","RBM34",1,235294498,235324772,-1,"protein_coding",23029,"RBM34",{"v":7.9464873955861e-09,"d":"7.95E-09"},-0.245373815,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":3.6e-14,"d":"3.60E-14"},"rs633269:rs199900492",6]
["ENSG00000163029","SMC6",2,17845079,17981509,-1,"protein_coding",79677,"SMC6",0.455419790303775,-0.256064404,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":7.4e-18,"d":"7.40E-18"},"rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854",7]
["ENSG00000151379","MSGN1",2,17997763,17998368,1,"protein_coding",343930,"MSGN1",0.191097329641165,0.290090795,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":7.4e-18,"d":"7.40E-18"},"rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854",7]
["ENSG00000240857","RDH14",2,18735989,18741946,-1,"protein_coding",57665,"RDH14",0.232943493348579,-0.65948759,0,0,0,"NA","NA","NA","NA","Yes","IMR90:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908","07:08:00"]
["ENSG00000183891","TTC32",2,20096404,20101747,-1,"protein_coding",130502,"TTC32",0.0898978964968043,0.090613208,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2e-20,"d":"2.00E-20"},"rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs2881925:rs907866;rs2881925",7]
["ENSG00000118965","WDR35",2,20110021,20189892,-1,"protein_coding",57539,"WDR35",{"v":2.64838406754913e-16,"d":"2.65E-16"},0.068467282,0,0,5,{"v":2.82344e-05,"d":"2.82E-05"},{"v":1.86848e-12,"d":"1.87E-12"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2e-20,"d":"2.00E-20"},"rs7600854;rs907869;rs907866;rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854:rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs2881925:rs907866;rs2881925",7]
["ENSG00000132031","MATN3",2,20191872,20212455,-1,"protein_coding",4148,"MATN3",{"v":1.61181027463323e-06,"d":"1.61E-06"},-0.325742707,0,0,19,{"v":6.26658e-08,"d":"6.27E-08"},{"v":7.07784e-56,"d":"7.08E-56"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-18,"d":"1.80E-18"},"rs13010903;rs7600854;rs907866;rs907869;rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs7600854:rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T",7]
["ENSG00000068697","LAPTM4A",2,20232411,20251789,-1,"protein_coding",9741,"LAPTM4A",0.503802410255576,0.09428312,0,0,1,{"v":1.47154e-06,"d":"1.47E-06"},{"v":1.35355e-33,"d":"1.35E-33"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":5.2E-22,"d":"5.20E-22"},"rs11687133;rs4075673:rs62120852:rs4564803;rs4296389:rs533617","07:08:00"]
["ENSG00000115884","SDC1",2,20400558,20425194,-1,"protein_coding",6382,"SDC1",0.290469547271798,-1.717413757,21,22.1,21,{"v":4.72337e-14,"d":"4.72E-14"},{"v":7.25196e-13,"d":"7.25E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","+","Yes","Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2e-20,"d":"2.00E-20"},"rs2881925;rs907866;rs11096646;2:20401858_TA_T;rs13010903;rs11687133;rs7600854;rs907869;rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs7600854:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs2881925:rs907866;rs2881925:rs11096646:rs11096646",7]
["ENSG00000055917","PUM2",2,20448452,20551995,-1,"protein_coding",23369,"PUM2",0.999922863782349,-1.032631297,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs11687133:rs13010903;rs7600854:rs7600854:rs13010903:rs907866;rs13010903;rs7600854:rs11096646:rs11096646;2:20401858_TA_T:2:20401858_TA_T:rs907866;rs13010903:rs907869:rs907866;rs907869:rs907866;rs2881925:rs907866:rs2881925:rs907866;rs2881925:rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908","07:08:00"]
["ENSG00000143878","RHOB",2,20646835,20649200,1,"protein_coding",388,"RHOB",0.245030976539202,-0.338452643,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":1.3E-49,"d":"1.30E-49"},"rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908",8]
["ENSG00000118960","HS1BP3",2,20760208,20850849,-1,"protein_coding",64342,"HS1BP3",0.000353324886507251,2.114325929,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs62120852:rs36134738:rs11685356;rs13414987:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs13414987:rs112907566:rs4564803;rs4296389:2:21425004_CAA_C:rs4075673:rs4296389:rs4426495:rs11680233:rs12691202:rs585967:2:21266774_GGCAGCGCCA_G;rs62122520:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:rs60403635:rs668948;rs585967;rs7419374:2:21277213_GCT_G:rs12471982:rs668948:rs111826230:rs34468875;2:21266774_GGCAGCGCCA_G;rs62122520:rs62122520:rs668948;rs34601365;rs432483:rs375330151:rs71435594:rs139289846:rs5829778:rs668948;rs7419374:rs668948;rs432483:rs34468875;rs62122520:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546",8]
["ENSG00000143869","GDF7",2,20866424,20873418,1,"protein_coding",151449,"GDF7",0.778067351749562,0.171953881,0,0,5,{"v":6.68769e-05,"d":"6.69E-05"},{"v":4.73948e-07,"d":"4.74E-07"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs949790;rs7566040;rs62120852:rs36134738:rs11685356;rs13414987:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs13414987:rs112907566:rs4564803;rs4296389:2:21425004_CAA_C:rs4075673:rs4296389:rs4426495:rs11680233:rs12691202:rs585967:2:21266774_GGCAGCGCCA_G;rs62122520:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:rs60403635:rs668948;rs585967;rs7419374:2:21277213_GCT_G:rs12471982:rs668948:rs111826230:rs34468875;2:21266774_GGCAGCGCCA_G;rs62122520:rs62122520:rs668948;rs34601365;rs432483:rs375330151:rs71435594:rs139289846:rs5829778:rs668948;rs7419374:rs668948;rs432483:rs34468875;rs62122520:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546",8]
["ENSG00000118961","C2orf43",2,20883788,21022882,-1,"protein_coding",60526,"C2orf43",0.00064748477489379,-0.605069014,0,0,61,{"v":6.33584e-07,"d":"6.34E-07"},{"v":1.70489e-23,"d":"1.70E-23"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs693;2:21266774_GGCAGCGCCA_G;rs62122520;rs34468875;rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs13414987:rs112907566:rs4564803;rs4296389:2:21425004_CAA_C:rs11685356;rs13414987:rs4075673:rs4296389:rs4426495:2:21266774_GGCAGCGCCA_G;rs62122520:rs668948;rs585967;rs7419374:rs12471982:rs668948:rs60403635:rs111826230:rs34468875;rs62122520:rs62122520:rs668948;rs34601365;rs432483:rs375330151:rs71435594:rs139289846:rs36134738:rs11680233:rs12691202:rs585967:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:2:21277213_GCT_G:rs5829778:rs668948;rs7419374:rs668948;rs432483:rs34468875;rs62122520:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546",8]
["ENSG00000084674","APOB",2,21224301,21266945,-1,"protein_coding",338,"APOB",{"v":5.49085163436995e-16,"d":"5.49E-16"},-0.34689194,57,24.9,444,{"v":4.92464e-29,"d":"4.92E-29"},{"v":1.88901e-24,"d":"1.89E-24"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs12713956;rs62122481;rs693;rs4564803;rs11680233;rs533617;rs74410908;rs12691202;rs112907566;rs585967;2:21266774_GGCAGCGCCA_G;rs62122520;rs668948;rs17398765;rs60403635;rs7419374;rs62120852;rs4296389;rs4075673;rs34468875;rs949790;rs4635554;rs7566040;rs11685356;rs13414987;rs12471982;rs34601365;rs432483;rs10177017;rs312033;rs4426495;rs36134738;rs71435594;rs5829778;rs1848922;rs7571647;rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:2:21266774_GGCAGCGCCA_G;rs62122520:rs668948;rs7419374:rs12471982:rs668948:rs60403635:rs111826230:rs34468875;rs62122520:rs62122520:rs668948;rs432483:rs375330151:rs71435594:rs139289846:rs5829778:rs668948;rs7419374:rs17398765:rs668948;rs432483:rs34468875;rs62122520:rs34601365:rs34468875:rs368220458:rs949790:rs4635554:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546",8]
["ENSG00000218819","TDRD15",2,21346789,21366144,1,"protein_coding",100129278,"TDRD15","NA","NA",40,10.66,43,{"v":9.33199e-09,"d":"9.33E-09"},{"v":4.5811e-10,"d":"4.58E-10"},"GTEx/v8/Liver","-","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-49,"d":"1.30E-49"},"rs17398765;rs62122520;rs668948;rs7419374;rs34601365;rs432483;rs34468875;2:21266774_GGCAGCGCCA_G;rs375330151;rs12471982;rs5829778;rs62122520:rs668948;rs585967;rs7419374:rs12471982:rs668948:rs60403635:rs111826230:rs34468875;rs62122520:rs62122520:rs668948;rs432483:rs375330151:rs71435594:rs139289846:rs668948;rs7419374:rs34601365:rs17398765:rs5829778:rs34468875:rs368220458:rs949790:rs4635554:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546:rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs11680233:rs12691202:rs112907566:rs585967:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:2:21277213_GCT_G",8]
["ENSG00000119771","KLHL29",2,23608088,23931481,1,"protein_coding",114818,"KLHL29","NA",-0.399831988,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.3E-49,"d":"1.30E-49"},"rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs11680233:rs12691202:rs112907566:rs585967:2:21266774_GGCAGCGCCA_G;rs62122520:rs668948;rs585967:2:21266774_GGCAGCGCCA_G:rs17398765:rs60403635:rs668948;rs585967;rs7419374:2:21277213_GCT_G:rs12471982:rs668948;rs7419374:rs668948;rs34601365;rs432483:rs34468875;2:21266774_GGCAGCGCCA_G;rs62122520:rs34601365:rs5829778:rs111826230:rs34468875:rs368220458:rs949790:rs4635554:rs375330151:rs668948:rs62122520:rs71435594:rs139289846:rs432483:rs432483;rs10177017:rs7419374:rs35239705:rs432483;rs1848922;rs10177017;rs7571647:rs7566040:rs78620068;rs7571647:rs949790;rs7566040:rs34478966:rs10177017:rs312033:rs432483;rs312033:rs1848922:rs10177017;rs7571647:rs7571647:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546",8]
["ENSG00000224361","AC011239.1",2,23729913,23747214,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-49,"d":"1.30E-49"},"rs62120852:rs4564803:rs11685356:rs12713956:rs62122481:rs693:rs4564803;rs11680233:rs533617:rs74410908:rs693;rs74410908:rs219546:rs78620068:rs58953077:rs4665698:rs58953077;rs219546",8]
["ENSG00000143970","ASXL2",2,25956622,26101385,-1,"protein_coding",55252,"ASXL2",0.992738818422806,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.3E-14,"d":"1.30E-14"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000268412","AC013449.1",2,26251074,26251481,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.3E-14,"d":"1.30E-14"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000084733","RAB10",2,26256976,26360323,1,"protein_coding",10890,"RAB10",0.944404791408518,-0.583904709,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.3E-14,"d":"1.30E-14"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000173567","GPR113",2,26531041,26569685,-1,"protein_coding",165082,"GPR113",{"v":1.48528745876047E-10,"d":"1.49E-10"},0.291622367,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.3E-14,"d":"1.30E-14"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A",9]
["ENSG00000157856","DRC1",2,26624784,26679579,1,"protein_coding",92749,"DRC1",{"v":1.30453003302834e-10,"d":"1.30E-10"},0.353225525,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8e-21,"d":"1.80E-21"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000213699","SLC35F6",2,26987152,27004099,1,"protein_coding",54978,"SLC35F6",0.0161307579092324,-0.353050684,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8e-21,"d":"1.80E-21"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000115163","CENPA",2,26987157,27023935,1,"protein_coding",1058,"CENPA",0.139975206060218,-0.80838147,0,0,6,{"v":2.63678e-05,"d":"2.64E-05"},{"v":8.50209e-21,"d":"8.50E-21"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.8e-21,"d":"1.80E-21"},"rs780090;rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978",9]
["ENSG00000084764","MAPRE3",2,27193480,27250064,1,"protein_coding",22924,"MAPRE3",0.799864407370243,-0.767319281,0,0,5,0.000153562,{"v":6.08981e-07,"d":"6.09E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Adult_Cortex:Fetal_Cortex:Spleen:GM12878:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.5e-50,"d":"2.50E-50"},"rs145508558;2:28122343_GT_G;rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs1395:rs780090:2:27498734_ACCCCCG_A:rs4665377:rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326",9]
["ENSG00000119777","TMEM214",2,27255778,27264563,1,"protein_coding",54867,"TMEM214",0.00116735534958103,-0.517227915,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs1395:rs780090:2:27498734_ACCCCCG_A:rs4665377:rs4665978",9]
["ENSG00000084693","AGBL5",2,27265232,27293490,1,"protein_coding",60509,"AGBL5",0.0206948513459665,-0.378650928,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":2.5e-50,"d":"2.50E-50"},"rs1395:rs1395;rs4665377:rs780090:2:27498734_ACCCCCG_A:rs4665377:rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326",9]
["ENSG00000228474","OST4",2,27293340,27294641,-1,"protein_coding",100128731,"OST4","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs1395:rs780090:2:27498734_ACCCCCG_A:rs4665377",9]
["ENSG00000138080","EMILIN1",2,27301435,27309271,1,"protein_coding",11117,"EMILIN1",0.00521656081419512,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377:rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs1395:2:27498734_ACCCCCG_A:rs780090",9]
["ENSG00000138030","KHK",2,27309615,27323640,1,"protein_coding",3795,"KHK",{"v":5.36079485314004e-05,"d":"5.36E-05"},"NA",0,0,101,{"v":1.27581e-05,"d":"1.28E-05"},{"v":2.2178e-62,"d":"2.22E-62"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377;rs3817588;rs145508558;2:28122343_GT_G;rs13013484;rs6714106;rs1395:rs780090:rs1395;rs4665377:2:27498734_ACCCCCG_A:rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978",9]
["ENSG00000138028","CGREF1",2,27321757,27341995,-1,"protein_coding",10669,"CGREF1",{"v":5.50290788195318E-8,"d":"5.50E-08"},0.491986309,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs780090:rs1395;rs4665377:rs1395:rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs3817588:2:27498734_ACCCCCG_A",9]
["ENSG00000143994","ABHD1",2,27346682,27353680,1,"protein_coding",84696,"ABHD1",{"v":1.06027288753589e-21,"d":"1.06E-21"},-0.251069432,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs780090:rs1395;rs4665377:rs1395:rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs4665978:rs3817588:2:27498734_ACCCCCG_A",9]
["ENSG00000138073","PREB",2,27353624,27357543,-1,"protein_coding",10113,"PREB",0.0018983627682706,-0.154458724,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs80051818:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs1395;rs4665377:rs1395:rs780090:rs4665978:2:27498734_ACCCCCG_A:rs4665377",9]
["ENSG00000186143","C2orf53",2,27359723,27362278,-1,"protein_coding",339779,"C2orf53",{"v":1.54927478958821e-09,"d":"1.55E-09"},0.62491408,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-14,"d":"1.30E-14"},"rs1395:rs780090:rs1395;rs4665377:rs4665377:rs4665978;2:27498734_ACCCCCG_A:2:27498734_ACCCCCG_A",9]
["ENSG00000163792","TCF23",2,27371872,27376378,1,"protein_coding",150921,"TCF23",0.000503312310069814,-0.683069484,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-14,"d":"1.30E-14"},"rs1395;rs4665377:rs1395:rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs780090:2:27498734_ACCCCCG_A",9]
["ENSG00000138074","SLC5A6",2,27422455,27435826,-1,"protein_coding",8884,"SLC5A6",0.571968337581082,-0.400099261,34,22.3,254,{"v":4.48883e-22,"d":"4.49E-22"},{"v":1.13875E-17,"d":"1.14E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377;rs780090;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27739880_CT_C;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs1395:rs780090:2:27498734_ACCCCCG_A:rs4665377",9]
["ENSG00000138085","ATRAID",2,27434895,27440046,1,"protein_coding",51374,"ATRAID",0.00791394898030435,"NA",22,15.27,245,{"v":2.34859e-32,"d":"2.35E-32"},{"v":5.3045e-26,"d":"5.30E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90",{"v":8.7e-55,"d":"8.70E-55"},"rs1395;rs4665377;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;rs3817588;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs1395:rs780090:2:27498734_ACCCCCG_A:rs4665377",9]
["ENSG00000084774","CAD",2,27440258,27466811,1,"protein_coding",790,"CAD",0.999999701880854,-0.710759294,46,15.27,240,{"v":1.82619e-25,"d":"1.83E-25"},{"v":9.08683e-20,"d":"9.09E-20"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27498734_ACCCCCG_A:rs80051818:rs1395;rs4665377:rs4665978;2:27694905_CA_C:rs1260326:rs1395:rs780090:2:27498734_ACCCCCG_A:rs4665377:rs4665978",9]
["ENSG00000115194","SLC30A3",2,27476552,27498685,-1,"protein_coding",7781,"SLC30A3",0.64608387237045,-0.660463482,34,12.98,1,{"v":2.22523e-09,"d":"2.23E-09"},{"v":7.40729e-24,"d":"7.41E-24"},"GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377;rs780090;2:27498734_ACCCCCG_A;rs67086575;rs1395:rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs780090",9]
["ENSG00000163793","DNAJC5G",2,27498289,27504367,1,"protein_coding",285126,"DNAJC5G",3.97478941010456E-3,-0.706717729,12,6.966,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377;2:27498734_ACCCCCG_A;rs780090;rs1395:rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs780090",9]
["ENSG00000138100","TRIM54",2,27505260,27530307,1,"protein_coding",57159,"TRIM54",{"v":8.24707898322991E-7,"d":"8.25E-07"},-1.053267254,19,8.663,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"2:27498734_ACCCCCG_A;rs780090;rs1395;rs4665377;rs4665377:rs1395:rs4665978;2:27498734_ACCCCCG_A:rs80051818:rs4665978:rs4665978;2:27694905_CA_C:rs1260326:rs780090",9]
["ENSG00000163794","UCN",2,27530268,27531313,-1,"protein_coding",7349,"UCN",0.517240162953561,-0.107138113,9,6.564,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.9e-10,"d":"2.90E-10"},"rs780090;rs4665377;rs1395;rs1395:rs1395",9]
["ENSG00000115204","MPV17",2,27532360,27548547,-1,"protein_coding",4358,"MPV17",{"v":1.10286841801097E-8,"d":"1.10E-08"},-0.205368529,13,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":2.5e-50,"d":"2.50E-50"},"rs780090;rs4665377;rs1395;rs4665978;2:27498734_ACCCCCG_A;rs1395:rs1395;rs4665377:rs780090:rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs3817588:rs67798437:rs74175068:rs145508558:2:27498734_ACCCCCG_A",9]
["ENSG00000115207","GTF3C2",2,27548716,27579868,-1,"protein_coding",2976,"GTF3C2",0.999786435918561,-0.837016421,34,18.95,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs1395;rs4665377;rs4665978;2:27498734_ACCCCCG_A;rs80051818;rs4665377:rs1395:rs80051818:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27694905_CA_C:rs1260326:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs4665978:rs3817588:rs67798437:rs74175068:rs145508558:rs148887828:rs780090:rs780090;rs148887828:rs2141371:2:27498734_ACCCCCG_A:rs4665377:rs1728918:rs67086575:2:27694905_CA_C:rs2178198:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C",9]
["ENSG00000115211","EIF2B4",2,27587219,27593353,-1,"protein_coding",8890,"EIF2B4",0.832609528731968,-0.214235303,25,18.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs4665978;2:27498734_ACCCCCG_A;rs80051818;2:27694905_CA_C;rs1260326;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs4665978:rs1395;rs4665377:rs1395:rs3817588:rs67798437:rs74175068:rs145508558:rs148887828:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:27498734_ACCCCCG_A:rs4665377:rs1728918:rs67086575:2:27694905_CA_C:rs2178198:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C",9]
["ENSG00000115234","SNX17",2,27593389,27599995,1,"protein_coding",9784,"SNX17",0.686180301198043,-0.681943317,24,18.47,198,{"v":1.17643e-13,"d":"1.18E-13"},{"v":2.00912e-09,"d":"2.01E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;rs80051818;2:27694905_CA_C;rs1260326;rs1395;rs4665377;2:27739880_CT_C;rs74175068;2:28003616_TA_T;rs67798437;2:27498734_ACCCCCG_A:rs80051818:rs4665978;2:27694905_CA_C:rs4665978:rs1395;rs4665377:rs1395:rs3817588:rs67798437:rs74175068:rs145508558:rs148887828:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:27498734_ACCCCCG_A:rs4665377:rs1728918:rs67086575:2:27694905_CA_C:rs2178198:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C",9]
["ENSG00000163795","ZNF513",2,27600098,27603657,-1,"protein_coding",130557,"ZNF513",0.940738428263313,"NA",18,18.47,67,{"v":3.61445e-05,"d":"3.61E-05"},0.0342333,"GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-50,"d":"2.50E-50"},"rs80051818;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;rs3817588;rs145508558;rs13013484;2:27498734_ACCCCCG_A:rs1728918:rs4665978;2:27694905_CA_C:rs4665978:rs1395;rs4665377:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs148887828:rs67086575:rs780090:2:27694905_CA_C:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs2178198",9]
["ENSG00000115241","PPM1G",2,27604061,27632554,-1,"protein_coding",5496,"PPM1G",0.996010385533881,-0.482626092,49,12.85,260,{"v":1.94157e-13,"d":"1.94E-13"},{"v":1.67809e-09,"d":"1.68E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;rs1728918;rs1395;rs4665377;rs80051818;2:27739880_CT_C;rs67798437;rs2178198;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27694905_CA_C:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs148887828:rs67086575:rs780090:2:27694905_CA_C:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs2178198",9]
["ENSG00000115216","NRBP1",2,27650657,27665126,1,"protein_coding",29959,"NRBP1",0.999548511025196,-1.389706011,43,14.1,327,{"v":1.48664E-19,"d":"1.49E-19"},{"v":1.00894E-14,"d":"1.01E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs3817588;rs1395;rs4665377;rs780090;rs80051818;rs1260326;rs1728918;2:27739880_CT_C;rs67798437;rs74175068;rs67086575;2:28003616_TA_T;rs80051818:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27694905_CA_C:rs1260326:rs4665978:rs780090:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs145508558:rs67798437:rs74175068:rs1395;rs4665377:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs148887828:rs67086575:2:27694905_CA_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs2178198",9]
["ENSG00000157992","KRTCAP3",2,27665233,27669348,1,"protein_coding",200634,"KRTCAP3",0.0445235342133754,"NA",25,10.57,177,{"v":6.96594E-10,"d":"6.97E-10"},{"v":4.42568e-06,"d":"4.43E-06"},"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs3817588;rs1395;rs80051818;rs1260326;2:27739880_CT_C;rs67798437;2:27498734_ACCCCCG_A:rs4665978:rs1728918:rs74175068:rs145508558:rs67798437:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs80051818:rs4665978;2:27694905_CA_C:rs1260326:rs148887828:rs67086575:2:27694905_CA_C:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs2178198",9]
["ENSG00000138002","IFT172",2,27667238,27712656,-1,"protein_coding",26160,"IFT172",{"v":2.29011817971014E-18,"d":"2.29E-18"},-0.505254909,71,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs3817588;rs67086575;rs780090;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67798437:rs74175068:rs145508558:rs1395;rs4665377:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs148887828:rs80051818:rs1260326:rs1728918:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs2178198:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000115226","FNDC4",2,27714750,27718112,-1,"protein_coding",64838,"FNDC4",0.759219015798597,"NA",23,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs780090;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67798437:rs74175068:rs145508558:rs1395;rs4665377:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs148887828:rs80051818:rs1260326:rs1728918:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs2178198:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000084734","GCKR",2,27719709,27746554,1,"protein_coding",2646,"GCKR",{"v":3.58392509874806e-16,"d":"3.58E-16"},-0.155697744,67,15.52,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs780090;rs1260326;rs3817588;2:27739880_CT_C;rs80051818;rs74175068;rs145508558;rs67798437;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67798437:rs74175068:rs145508558:rs2178198:rs1395;rs4665377:rs80051818:rs1260326:rs3817588:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs148887828:rs1728918:rs67086575:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000233438","AC109829.1",2,27760253,27790011,1,"protein_coding","NA","NA","NA","NA",69,10.48,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs1260326;2:27739880_CT_C;rs3817588;rs4665978;rs74175068;rs145508558;rs67798437;rs13013484;2:27766414_CA_C;2:27786252_CTTTTTTTTTT_C;rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs3817588:rs67086575:rs780090:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs148887828:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T",9]
["ENSG00000221843","C2orf16",2,27799389,27805588,1,"protein_coding",84226,"C2orf16",{"v":3.91661992667067e-17,"d":"3.92E-17"},-0.329746802,23,17.52,3,{"v":4.21915e-06,"d":"4.22E-06"},0.0141403,"GTEx/v8/Liver","-","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs145508558;rs74175068;rs67798437;rs3817588;rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs3817588:rs67086575:rs780090:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs148887828:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T",9]
["ENSG00000243943","ZNF512",2,27805897,27858041,1,"protein_coding",84450,"ZNF512",0.949146986047491,-1.279253328,79,18.65,6,{"v":8.67923e-05,"d":"8.68E-05"},0.0461625,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs67798437;rs145508558;rs74175068;rs148887828;rs780090;rs2141371;rs13013484;2:28003616_TA_T;rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs780090:rs1395;rs4665377:rs3817588:rs74175068:rs145508558:rs67798437:rs80051818:rs1260326:rs67086575:2:27694905_CA_C:rs1728918:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs1260326;2:27739880_CT_C:2:27739880_CT_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C",9]
["ENSG00000176714","CCDC121",2,27848506,27851879,-1,"protein_coding",79635,"CCDC121",{"v":9.72713578876563e-05,"d":"9.73E-05"},-0.266319334,21,18.65,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs145508558;rs67798437;rs74175068;rs780090;rs148887828;rs2141371;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs3817588:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67086575:rs780090:2:27694905_CA_C:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs148887828:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs145508558;rs13013484:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs74175068;2:28003616_TA_T:rs2178198:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000198522","GPN1",2,27851114,27874375,1,"protein_coding",11321,"GPN1",0.0049035919998219,-0.238154635,22,14.13,216,{"v":7.93394e-08,"d":"7.93E-08"},0.000297808,"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs67798437;rs145508558;rs780090;rs74175068;rs148887828;rs2141371;rs13013484;2:28003616_TA_T;rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C;rs1260326;2:27739880_CT_C;2:27694905_CA_C:rs3817588:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67086575:rs780090:2:27694905_CA_C:rs80051818:rs1260326:rs67798437:rs74175068:rs145508558:rs148887828:rs1728918:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs145508558;rs13013484:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs74175068;2:28003616_TA_T:rs2178198:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000119760","SUPT7L",2,27873679,27886676,-1,"protein_coding",9913,"SUPT7L",0.833193338587633,-0.966218532,11,10.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":8.7e-55,"d":"8.70E-55"},"rs145508558;rs13013484;rs74175068;2:28003616_TA_T;rs2178198;rs780090:rs1395;rs4665377:rs1395:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs80051818:rs1260326:rs1728918:rs3817588:rs67086575:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000163798","SLC4A1AP",2,27886338,27917840,1,"protein_coding",22950,"SLC4A1AP",{"v":7.73999085415032e-07,"d":"7.74E-07"},-0.546764453,8,15.03,131,{"v":4.00834e-08,"d":"4.01E-08"},{"v":8.71618E-6,"d":"8.72E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":8.7e-55,"d":"8.70E-55"},"rs145508558;rs13013484;rs74175068;2:28003616_TA_T;rs2178198;rs67798437;rs2141371;2:28122343_GT_G;rs6714106;rs4665978;rs780090:rs1395;rs4665377:rs1395:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs80051818:rs1260326:rs1728918:rs3817588:rs67086575:2:27694905_CA_C:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs74175068:rs145508558:rs67798437:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813",9]
["ENSG00000205334","AC074091.13",2,27928653,27938599,-1,"protein_coding",100129995,"LINC01460","NA","NA",10,18.44,40,{"v":1.69114e-05,"d":"1.69E-05"},0.0188373,"GTEx/v8/Artery_Aorta","+","Yes","Adult_Cortex:Left_Ventricle:Liver:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-19,"d":"8.70E-19"},"rs74175068;2:28003616_TA_T;rs145508558;rs13013484;2:28122343_GT_G:rs13013484:rs145508558;rs13013484:rs764054216:2:28003616_TA_T:2:28122343_GT_G:2:28122343_GT_G;rs6714106:rs937813:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484;2:28122343_GT_G;rs6714106:rs6714106:2:28206809_CT_C",9]
["ENSG00000243147","MRPL33",2,27994584,28210954,1,"protein_coding",9553,"MRPL33",0.749164756585824,-0.22012956,200,19.66,264,{"v":3.59543e-09,"d":"3.60E-09"},{"v":2.0615e-05,"d":"2.06E-05"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":8.7e-19,"d":"8.70E-19"},"rs13013484;2:28003616_TA_T;rs145508558;2:28122343_GT_G;rs764054216;rs6714106;2:28206809_CT_C;rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs13013484;2:28122343_GT_G:2:28122343_GT_G:rs13013484;rs6714106:2:28122343_GT_G;rs6714106:rs937813:rs764054216:2:28003616_TA_T:rs6714106:2:28206809_CT_C:rs2178198",9]
["ENSG00000268656","AC110084.1",2,27998851,28009186,-1,"protein_coding","NA","NA","NA","NA",20,19.66,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.5e-51,"d":"4.50E-51"},"rs145508558;rs13013484;2:28122343_GT_G;rs764054216;2:28003616_TA_T;rs4665978;2:27498734_ACCCCCG_A:rs1260326;2:27739880_CT_C:rs3817588:rs4665978:rs80051818:rs13013484;rs6714106:2:28122343_GT_G:rs2178198:rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:2:28122343_GT_G;rs6714106:rs937813:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:2:28003616_TA_T:rs13013484;2:28122343_GT_G:rs6714106:2:28206809_CT_C",9]
["ENSG00000171174","RBKS",2,28004231,28113965,-1,"protein_coding",64080,"RBKS",{"v":1.93197572918752E-5,"d":"1.93E-05"},-0.689745423,135,19.66,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-19,"d":"8.70E-19"},"rs13013484;rs145508558;rs764054216;2:28122343_GT_G;2:28003616_TA_T;rs6714106;rs6714106:2:28122343_GT_G:rs13013484;2:28122343_GT_G:2:28003616_TA_T:2:28122343_GT_G;rs6714106:rs937813:rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs764054216:2:28206809_CT_C",9]
["ENSG00000158019","BRE",2,28112808,28561768,1,"protein_coding",9577,"BRE",0.279976282823241,"NA",113,16.05,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-19,"d":"8.70E-19"},"rs13013484;2:28122343_GT_G;rs6714106;2:28003616_TA_T;2:28206809_CT_C;rs2178198;rs937813;2:28122343_GT_G:rs13013484;rs6714106:2:28003616_TA_T:2:28122343_GT_G;rs6714106:rs937813:rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs764054216:2:28206809_CT_C",9]
["ENSG00000075426","FOSL2",2,28615315,28640179,1,"protein_coding",2355,"FOSL2",0.925334261981773,-2.20415963,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Aorta:Bladder:Left_Ventricle:Liver:Lung:Pancreas:Psoas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-50,"d":"2.50E-50"},"rs74175068;2:28003616_TA_T:rs145508558:rs145508558;rs13013484:rs13013484:2:28003616_TA_T:rs764054216:rs13013484;2:28122343_GT_G:2:28122343_GT_G:rs13013484;2:28122343_GT_G;rs6714106:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs80051818:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs1260326:rs67086575:rs780090:2:27694905_CA_C:rs74175068:rs67798437:rs780090;rs148887828:rs2141371:rs6714106:2:28122343_GT_G;rs6714106:2:28206809_CT_C:rs937813:rs3817588:rs148887828",9]
["ENSG00000163803","PLB1",2,28680012,28866654,1,"protein_coding",151056,"PLB1",{"v":1.9931529274349E-56,"d":"1.99E-56"},0.411383907,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs67798437:rs74175068:rs145508558:rs74175068;2:28003616_TA_T:2:28122343_GT_G:rs13013484;2:28122343_GT_G:rs13013484;2:28122343_GT_G;rs6714106:2:28003616_TA_T:rs148887828:rs145508558;rs13013484:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484:rs764054216:rs6714106:2:28122343_GT_G;rs6714106:rs937813:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs4665978:rs4665978;2:27498734_ACCCCCG_A:rs67086575:rs780090:2:27694905_CA_C:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C:rs780090;rs148887828:rs2141371:2:28206809_CT_C:rs1260326:rs3817588:rs1260326;2:27739880_CT_C:2:27739880_CT_C:rs80051818",9]
["ENSG00000213639","PPP1CB",2,28974506,29025806,1,"protein_coding",5500,"PPP1CB",0.997194974203565,0.001839166,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.5e-26,"d":"3.50E-26"},"rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs4665978;2:27498734_ACCCCCG_A;2:27694905_CA_C:rs780090:rs74175068;2:28003616_TA_T:rs13013484;2:28122343_GT_G:rs13013484:rs145508558;rs13013484:rs764054216:2:28003616_TA_T:2:28122343_GT_G;rs6714106:2:28122343_GT_G:rs937813:rs67086575:2:27694905_CA_C:rs74175068:rs145508558:rs67798437:rs780090;rs148887828:rs2141371:rs2178198:rs1317580:2:28003616_TA_T;rs1317580:rs13013484;2:28122343_GT_G;rs6714106:rs6714106:2:28206809_CT_C",9]
["ENSG00000163806","SPDYA",2,29005383,29073477,1,"protein_coding",245711,"SPDYA",0.166884223990281,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.5e-26,"d":"3.50E-26"},"rs74175068:rs145508558:rs67798437:rs780090:rs780090;rs148887828:rs2141371:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs2178198:rs1317580:2:28122343_GT_G:2:28003616_TA_T;rs1317580:rs13013484:2:28003616_TA_T:rs13013484;2:28122343_GT_G:rs764054216:rs13013484;2:28122343_GT_G;rs6714106:2:28122343_GT_G;rs6714106:rs937813:rs6714106:2:28206809_CT_C",9]
["ENSG00000171103","TRMT61B",2,29072687,29093167,-1,"protein_coding",55006,"TRMT61B",{"v":4.00751770882134e-06,"d":"4.01E-06"},-0.602142186,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":3.5e-26,"d":"3.50E-26"},"rs1395;rs4665377:rs4665978;2:27498734_ACCCCCG_A:rs4665978:rs74175068;2:28003616_TA_T:rs13013484;2:28122343_GT_G:rs13013484:rs145508558;rs13013484:rs74175068:rs145508558:rs67798437:rs780090",9]
["ENSG00000163811","WDR43",2,29117509,29171088,1,"protein_coding",23160,"WDR43",0.998942440488972,1.455113129,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":8.7e-19,"d":"8.70E-19"},"rs13013484;2:28122343_GT_G:rs13013484:rs145508558;rs13013484:rs74175068;2:28003616_TA_T:rs145508558",9]
["ENSG00000171094","ALK",2,29415640,30144432,-1,"protein_coding",238,"ALK",0.522362516846561,-0.624899803,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.6e-26,"d":"1.60E-26"},"rs74175068:rs145508558;rs13013484:rs67798437:rs145508558:2:27766414_CA_C:2:27786252_CTTTTTTTTTT_C",9]
["ENSG00000115944","COX7A2L",2,42560686,42652228,-1,"protein_coding",9167,"COX7A2L",0.00041024940040515,-0.898949558,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000171126","KCNG3",2,42669157,42721237,-1,"protein_coding",170850,"KCNG3",0.0405974403481221,0.146034981,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000057935","MTA3",2,42721709,42984087,1,"protein_coding",57504,"MTA3",0.855163471897877,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000162881","OXER1",2,42989642,42991401,-1,"protein_coding",165140,"OXER1",{"v":4.76881321179725e-07,"d":"4.77E-07"},0.339144756,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000115970","THADA",2,43393800,43823185,-1,"protein_coding",63892,"THADA",{"v":1.24008146143984E-28,"d":"1.24E-28"},-0.379900358,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000152527","PLEKHH2",2,43864412,43995126,1,"protein_coding",130271,"PLEKHH2",{"v":1.78874098604568e-26,"d":"1.79E-26"},0.460070846,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000138036","DYNC2LI1",2,44001178,44037149,1,"protein_coding",51626,"DYNC2LI1",{"v":8.37968944079953e-05,"d":"8.38E-05"},1.048101021,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000138075","ABCG5",2,44039611,44066004,-1,"protein_coding",64240,"ABCG5",{"v":1.89797083861304e-15,"d":"1.90E-15"},1.020983846,18,22.8,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534;rs4299376",10]
["ENSG00000143921","ABCG8",2,44066103,44105605,1,"protein_coding",64241,"ABCG8",{"v":3.74527259993631e-16,"d":"3.75E-16"},-0.050037409,35,22.8,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534;rs4299376;rs7598542",10]
["ENSG00000138095","LRPPRC",2,44113647,44223144,-1,"protein_coding",10128,"LRPPRC",0.000433777803620707,-0.577712281,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000138078","PREPL",2,44543420,44589001,-1,"protein_coding",9581,"PREPL",{"v":2.42946176486827e-11,"d":"2.43E-11"},0.105864684,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000143919","CAMKMT",2,44589089,44999731,1,"protein_coding",79823,"CAMKMT",{"v":5.14965805552299e-13,"d":"5.15E-13"},0.213319519,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":2.6e-16,"d":"2.60E-16"},"rs11887534:rs4299376:rs7598542",10]
["ENSG00000123607","TTC21B",2,166713985,166810353,-1,"protein_coding",79809,"TTC21B",{"v":3.38768007245796e-22,"d":"3.39E-22"},0.293795588,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000169432","SCN9A",2,167051695,167232503,-1,"protein_coding",6335,"SCN9A",{"v":9.30185484244833e-13,"d":"9.30E-13"},1.292595625,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000136546","SCN7A",2,167260083,167350757,-1,"protein_coding",6332,"SCN7A",{"v":1.72076245416042E-15,"d":"1.72E-15"},0.83121003,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000163092","XIRP2",2,167744997,168116263,1,"protein_coding",129446,"XIRP2",{"v":2.85559362075031e-37,"d":"2.86E-37"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000172318","B3GALT1",2,168675182,168730551,1,"protein_coding",8708,"B3GALT1",0.329724363511517,0.177549191,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000198648","STK39",2,168810530,169104651,-1,"protein_coding",27347,"STK39",0.999462431417641,-1.274787931,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000172292","CERS6",2,169312372,169631644,1,"protein_coding",253782,"CERS6",0.684541332373748,-0.789777756,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000163072","NOSTRIN",2,169643049,169722024,1,"protein_coding",115677,"NOSTRIN",{"v":3.5797265988291e-10,"d":"3.58E-10"},-0.276311026,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000152253","SPC25",2,169690642,169769881,-1,"protein_coding",57405,"SPC25",0.0594294501038599,-0.350386754,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000073734","ABCB11",2,169779448,169887832,-1,"protein_coding",8647,"ABCB11",{"v":2.18849485467569e-10,"d":"2.19E-10"},0.007239117,56,20.8,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000073737","DHRS9",2,169921299,169952677,1,"protein_coding",10170,"DHRS9",{"v":2.60804336160151e-07,"d":"2.61E-07"},0.13129231,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000081479","LRP2",2,169983619,170219195,-1,"protein_coding",4036,"LRP2",0.99999999999851,-0.83491165,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000163093","BBS5",2,170335688,170382432,1,"protein_coding",129880,"BBS5",2.59936459879345E-3,1.335741609,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000251569","RP11-724O16.1",2,170335990,170382432,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000222033","LINC01124",2,171568961,171571077,-1,"protein_coding",440925,"LINC01124","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000204335","SP5",2,171571861,171574588,1,"protein_coding",389058,"SP5",0.432721441198873,-0.845891251,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000204334","ERICH2",2,171640296,171655481,1,"protein_coding",285141,"ERICH2","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000128683","GAD1",2,171669723,171717661,1,"protein_coding",2571,"GAD1",0.82254015260978,0.540076803,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.4E-8,"d":"1.40E-08"},"rs3770586",11]
["ENSG00000109736","MFSD10",4,2932288,2936586,-1,"protein_coding",10227,"MFSD10",{"v":3.01777310462786e-07,"d":"3.02E-07"},"NA",0,0,1,{"v":8.5623e-05,"d":"8.56E-05"},0.0441429,"GTEx/v8/Adipose_Visceral_Omentum","+","No","NA",{"v":3.8e-05,"d":"3.80E-05"},"rs731450",12]
["ENSG00000188981","MSANTD1",4,3246096,3273465,1,"protein_coding",345222,"MSANTD1",0.32217221350423,-0.464369361,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":3.7e-17,"d":"3.70E-17"},"rs3748034:rs16844364:rs13108218:rs4690098:rs62275880:rs6818397:rs4690014:rs59950280:rs36205397",12]
["ENSG00000159788","RGS12",4,3294755,3441640,1,"protein_coding",6002,"RGS12",0.00056037428714452,0.073053441,20,17.61,1,{"v":2.03059e-05,"d":"2.03E-05"},0.00276351,"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":3.7e-17,"d":"3.70E-17"},"rs4690098;rs6818397;rs4690014;rs16844364;rs3748034;rs13108218;rs4690098:rs6818397:rs4690014:rs16844364",12]
["ENSG00000109758","HGFAC",4,3443614,3451211,1,"protein_coding",3083,"HGFAC",{"v":5.20820571636199e-07,"d":"5.21E-07"},-0.328343914,21,17.61,3,{"v":1.95178e-08,"d":"1.95E-08"},{"v":7.83151e-05,"d":"7.83E-05"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","No","NA",{"v":3.7e-17,"d":"3.70E-17"},"rs4690098;rs6818397;rs4690014;rs16844364;rs3748034;rs13108218;rs59950280",12]
["ENSG00000175920","DOK7",4,3465033,3503200,1,"protein_coding",285489,"DOK7",0.00480838202293031,1.760396669,54,12.55,5,{"v":2.169e-07,"d":"2.17E-07"},{"v":2.44181e-29,"d":"2.44E-29"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":3.7e-17,"d":"3.70E-17"},"rs3748034;rs62275880;rs36205397;rs731450;rs13108218;rs4690014;rs36205397:rs731450",12]
["ENSG00000163956","LRPAP1",4,3508103,3534286,-1,"protein_coding",4043,"LRPAP1",0.00608430596153667,1.96880545,50,12.55,31,{"v":5.25087e-07,"d":"5.25E-07"},{"v":6.09049e-37,"d":"6.09E-37"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":5e-08,"d":"5.00E-08"},"rs731450;rs36205397;rs62275880",12]
["ENSG00000268781","AL590235.1",4,3511523,3511678,-1,"protein_coding","NA","NA","NA","NA",27,12.55,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4e-08,"d":"4.00E-08"},"rs731450",12]
["ENSG00000184160","ADRA2C",4,3768075,3770251,1,"protein_coding",152,"ADRA2C",0.645951820563209,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.3e-05,"d":"1.30E-05"},"rs731450",12]
["ENSG00000163982","OTOP1",4,4190530,4228616,-1,"protein_coding",133060,"OTOP1",{"v":7.31470990584692e-16,"d":"7.31E-16"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":9.2e-11,"d":"9.20E-11"},"rs62275880:rs36205397",12]
["ENSG00000226894","TMPRSS11BNL",4,69054242,69083798,-1,"protein_coding",401136,"TMPRSS11BNL",0.315776901388964,0.704294788,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000185873","TMPRSS11B",4,69092371,69111438,-1,"protein_coding",132724,"TMPRSS11B",{"v":1.68050228934566e-11,"d":"1.68E-11"},0.053188955,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000083896","YTHDC1",4,69176105,69215807,-1,"protein_coding",91746,"YTHDC1",0.999999898691266,-1.324074711,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000087128","TMPRSS11E",4,69313167,69363322,1,"protein_coding",28983,"TMPRSS11E",{"v":3.75424420546756E-5,"d":"3.75E-05"},0.26253994,19,22.5,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000197888","UGT2B17",4,69402902,69434245,-1,"protein_coding",7367,"UGT2B17",0.0102556056990611,0.903832175,2,1.962,20,{"v":3.25155e-15,"d":"3.25E-15"},{"v":5.32642E-14,"d":"5.33E-14"},"GTEx/v8/Liver","+","No","NA",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000109181","UGT2B10",4,69681711,69696914,1,"protein_coding",7365,"UGT2B10",{"v":5.50615564451229e-15,"d":"5.51E-15"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000135220","UGT2A3",4,69794181,69817509,-1,"protein_coding",79799,"UGT2A3",{"v":5.00169122908013e-06,"d":"5.00E-06"},0.402338316,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000171234","UGT2B7",4,69917081,69978705,1,"protein_coding",7364,"UGT2B7",{"v":3.49679084556951e-08,"d":"3.50E-08"},0.82500636,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000213759","UGT2B11",4,70065669,70080449,-1,"protein_coding",10720,"UGT2B11",{"v":3.14709815271135E-13,"d":"3.15E-13"},0.706560698,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000135226","UGT2B28",4,70146217,70160768,1,"protein_coding",54490,"UGT2B28",{"v":6.44395718165304e-08,"d":"6.44E-08"},-0.023007521,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000156096","UGT2B4",4,70345883,70391732,-1,"protein_coding",7363,"UGT2B4",{"v":8.44718840140518e-11,"d":"8.45E-11"},0.451804371,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000173610","UGT2A1",4,70454135,70518965,-1,"protein_coding",10941,"UGT2A1",{"v":2.73195454586815E-11,"d":"2.73E-11"},-0.281771314,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000271271","UGT2A2",4,70454135,70505360,-1,"protein_coding",574537,"UGT2A2",{"v":2.32634948326899e-07,"d":"2.33E-07"},-0.31710536,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000270386","UGT2A1",4,70454912,70518967,-1,"protein_coding",10941,"UGT2A1","NA",-0.281771314,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":3.1E-9,"d":"3.10E-09"},"rs4860948",13]
["ENSG00000214944","ARHGEF28",5,72921983,73237818,1,"protein_coding",64283,"ARHGEF28",{"v":1.82695073178584E-10,"d":"1.83E-10"},0.074538928,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.6e-29,"d":"4.60E-29"},"rs7700719:rs144070522:rs73125245:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732",14]
["ENSG00000171617","ENC1",5,73923234,73937249,-1,"protein_coding",8507,"ENC1",0.879896897082265,-1.299228704,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.2E-23,"d":"1.20E-23"},"rs253392:rs253392;rs40059:rs4704210;rs253412",14]
["ENSG00000049860","HEXB",5,73935848,74018472,1,"protein_coding",3074,"HEXB",{"v":1.49158509655983e-05,"d":"1.49E-05"},0.069875862,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.2E-23,"d":"1.20E-23"},"rs253392:rs253392;rs40059:rs4704210;rs253412",14]
["ENSG00000164347","GFM2",5,74017029,74063196,-1,"protein_coding",84340,"GFM2",{"v":1.22849095804363E-8,"d":"1.23E-08"},0.221147401,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs7700719:rs144070522:rs73125245:rs6861101;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs72633976;rs4704171:rs1115091;rs10051260:rs10051260:rs1115091:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496",14]
["ENSG00000164346","NSA2",5,74062817,74072737,1,"protein_coding",10412,"NSA2",0.686235240727363,-0.093199602,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs7700719:rs144070522:rs73125245:rs6861101;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs72633976;rs4704171:rs1115091;rs10051260:rs10051260:rs1115091:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496",14]
["ENSG00000198780","FAM169A",5,74073399,74162776,-1,"protein_coding",26049,"FAM169A",0.998576224772368,-1.163574677,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs253392:rs253412;rs56912706;rs40059:rs40059:rs253412;rs40059:rs253412:rs73125245:rs7706858:rs6861101:rs144070522:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs72633976;rs4704171:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs253412;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs7700719:rs9293656:rs72633976;5:74733593_TA_T:rs376481168",14]
["ENSG00000176928","GCNT4",5,74323289,74326724,-1,"protein_coding",51301,"GCNT4",0.0212350420721519,1.250076366,30,18.72,406,{"v":5.81264e-30,"d":"5.81E-30"},{"v":1.979e-24,"d":"1.98E-24"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs7706858;rs73125245;rs6861101;rs144070522;rs7700719;rs4555772;rs7714420;rs10942732;rs4704187;rs151000110;rs9293656;rs4704210;rs1820163;rs253412;rs56912706;rs888789;rs258496;rs72633976;rs4704171:rs10942732:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs144070522:rs9293656:rs72633976;5:74733593_TA_T:rs376481168:rs112789140:rs7700719:rs73125245:rs253392:rs253412;rs40059:rs40059:rs253412;rs40059:rs253412:5:74973446_TA_T:rs253412;rs888789:rs888789:rs6861101;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs4704187;rs10942732:rs55810502:rs4704171:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs56912706;rs258496:rs4704187:5:74519954_TTA_T",14]
["ENSG00000145700","ANKRD31",5,74364100,74532703,-1,"protein_coding",256006,"ANKRD31","NA","NA",302,16.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle",{"v":4.7e-28,"d":"4.70E-28"},"rs10942732;rs4704187;rs4704171;rs55810502;rs72633976;rs151000110;5:74519954_TTA_T;rs9293656:rs4704210:rs72633976:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496",14]
["ENSG00000113161","HMGCR",5,74632154,74657929,1,"protein_coding",3156,"HMGCR",0.999836644997739,-0.514442124,42,12.4,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878",{"v":3.6e-29,"d":"3.60E-29"},"rs6895057;rs4704210;rs9293656;rs72633976;5:74733593_TA_T;rs1820163;5:74733593_TA_T:rs9293656:rs72633976:rs4704210;rs1115091:rs40059:rs253412;rs56912706;rs888789:rs888789:rs253412;rs40059:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs253392:rs253412;rs40059:rs253412:5:74973446_TA_T",14]
["ENSG00000113163","COL4A3BP",5,74664311,74807963,-1,"protein_coding",10087,"COL4A3BP",0.979474243191344,-1.648108059,107,13.82,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs4704210;rs72633976;rs9293656;5:74733593_TA_T;rs376481168;rs1115091;rs151000110;rs72633976:rs72633976;5:74733593_TA_T:rs9293656:rs4704210:rs4704210;rs1115091:rs4704187;rs10942732:rs4704171:rs10942732:rs72633976;rs4704171:rs253392:rs253412;rs56912706;rs40059:rs40059:rs253412;rs40059:rs253412:rs4704210;rs1820163:rs376481168:rs144070522:5:74973446_TA_T:rs253412;rs888789:rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs7700719:rs73125245:rs4704210;rs253412:rs542624913",14]
["ENSG00000122008","POLK",5,74807581,74896969,1,"protein_coding",51426,"POLK",{"v":5.99896012883471e-07,"d":"6.00E-07"},-0.474863143,69,14.63,463,{"v":1.94991e-11,"d":"1.95E-11"},{"v":3.07855e-07,"d":"3.08E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-29,"d":"3.60E-29"},"rs72633976;5:74733593_TA_T;rs9293656;rs4704210;rs144070522;rs4555772;rs7706858;rs1820163;rs1115091;rs253412;rs10942732;rs10051260;rs7700719;rs6861101;rs4704187;rs4704171;rs253392;rs72633976:rs72633976;5:74733593_TA_T:rs9293656:rs4704210:rs4704210;rs1115091:rs4704187;rs10942732:rs4704171:rs10942732:rs72633976;rs4704171:rs253392:rs253412;rs56912706;rs40059:rs40059:rs253412;rs40059:rs253412:rs4704210;rs1820163:rs376481168:rs144070522:5:74973446_TA_T:rs253412;rs888789:rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs7700719:rs73125245:rs4704210;rs253412:rs542624913",14]
["ENSG00000189045","ANKDD1B",5,74907284,74967671,1,"protein_coding",728780,"ANKDD1B","NA",0.593695416,85,45,219,{"v":6.59244e-10,"d":"6.59E-10"},{"v":8.71784e-08,"d":"8.72E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs9293656;rs72633976;5:74733593_TA_T;rs4704210;rs253392;rs40059;rs253412;rs542624913;rs56912706;5:74973446_TA_T;rs4704171;rs6895057;rs888789;rs1115091;rs10051260;rs144070522;rs73125245;rs55810502;rs10942732;rs151000110;rs7706858;rs7714420;rs4555772;rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs144070522:rs253392:rs253412;rs40059:rs40059:rs253412;rs40059:rs253412:5:74973446_TA_T:rs253412;rs888789:rs888789:rs7700719:rs73125245:rs6861101;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs4704210;rs1115091:rs253392;rs40059:rs4704210;rs253412:rs542624913:rs253412;rs56912706:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs55810502:rs72633976;rs4704171:rs1115091;rs10051260:rs10051260:rs1115091",14]
["ENSG00000152359","POC5",5,74969949,75013313,-1,"protein_coding",134359,"POC5",0.00213816175598754,0.193562311,96,45,322,{"v":8.77814e-27,"d":"8.78E-27"},{"v":3.83637e-25,"d":"3.84E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.6e-29,"d":"3.60E-29"},"rs253392;rs253412;rs56912706;rs40059;5:74973446_TA_T;rs888789;rs151000110;rs73125245;rs4704171;rs55810502;rs72633976;rs1115091;rs144070522;5:74733593_TA_T;rs4704210;rs112789140;rs258496;rs10051260;rs9293656;rs9293656:rs72633976:rs72633976;5:74733593_TA_T:rs4704210;rs6895057:rs4704210:rs4704210;rs1820163:rs72633976;rs4704171:rs10942732:rs1115091;rs10051260:rs10051260:rs1115091:rs144070522:rs376481168:rs4704187;rs10942732:rs55810502:rs4704171:rs4704210;rs1115091:rs7700719:rs73125245:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs253392:rs253412;rs40059:rs40059:rs253412;rs40059:rs253412:5:74973446_TA_T:rs253412;rs888789:rs888789:rs6861101;rs7706858:rs4555772;rs7706858:rs4555772:rs151000110:rs258496:rs112789140:rs253392;rs40059:rs4704210;rs253412:rs542624913",14]
["ENSG00000122012","SV2C",5,75378997,75649764,1,"protein_coding",22987,"SV2C",{"v":6.35694393316701e-05,"d":"6.36E-05"},0.609630272,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.6e-16,"d":"3.60E-16"},"rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732",14]
["ENSG00000145703","IQGAP2",5,75699074,76003957,1,"protein_coding",10788,"IQGAP2",{"v":4.102950079501e-15,"d":"4.10E-15"},-0.157179038,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs7700719:rs73125245:rs6861101;rs7706858:rs4555772;rs7706858:rs4555772:rs7706858:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732:rs72633976;rs4704171:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs144070522:rs9293656:rs72633976;5:74733593_TA_T:rs376481168",14]
["ENSG00000164220","F2RL2",5,75911307,75919259,-1,"protein_coding",2151,"F2RL2",{"v":7.36707093228916e-07,"d":"7.37E-07"},0.52221208,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs7700719:rs144070522:rs73125245:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496",14]
["ENSG00000181104","F2R",5,76011868,76031606,1,"protein_coding",2149,"F2R",0.0412384876728322,-0.795910613,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168:rs7700719:rs144070522:rs73125245:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496",14]
["ENSG00000164251","F2RL1",5,76114758,76131140,1,"protein_coding",2150,"F2RL1",2.02251710092648E-3,-0.779081854,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":4.6e-29,"d":"4.60E-29"},"rs4704187;rs10942732:rs4704171:rs10942732:rs72633976;rs4704171:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168",14]
["ENSG00000145708","CRHBP",5,76248538,76276983,1,"protein_coding",1393,"CRHBP",0.989594470418958,-0.435834082,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.6e-29,"d":"4.60E-29"},"rs112789140:rs144070522:rs7700719:rs73125245:rs7706858:rs6861101:rs7714420:rs7714420;rs4555772:rs10942732:rs4704187;rs10942732:rs4704171:rs55810502:rs72633976;rs4704171:rs4704210:rs1115091;rs10051260:rs4704210;rs1820163:rs10051260:rs72633976:rs1115091:rs9293656:rs72633976;5:74733593_TA_T:rs376481168:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs56912706;rs258496",14]
["ENSG00000164252","AGGF1",5,76325076,76361059,1,"protein_coding",55109,"AGGF1",{"v":6.09962982121775e-05,"d":"6.10E-05"},-0.704749026,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.6e-29,"d":"4.60E-29"},"rs7700719:rs144070522:rs73125245:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732:rs4704210:rs9293656:rs4704210;rs1820163:rs72633976:rs72633976;5:74733593_TA_T:rs376481168",14]
["ENSG00000132846","ZBED3",5,76367897,76383148,-1,"protein_coding",84327,"ZBED3",0.0784364357896077,0.791120221,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.6e-16,"d":"3.60E-16"},"rs7700719:rs144070522:rs73125245:rs4704187;rs10942732:rs55810502:rs4704171:rs10942732:rs40059:rs253412;rs56912706;rs888789:rs253412;rs56912706:rs253392;rs40059:rs151000110:rs56912706;rs40059:rs56912706:rs112789140:rs56912706;rs258496",14]
["ENSG00000082516","GEMIN5",5,154266976,154317769,-1,"protein_coding",25929,"GEMIN5",{"v":3.13420201203131E-14,"d":"3.13E-14"},-0.693060045,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.7e-27,"d":"6.70E-27"},"rs4704830:rs6882345:rs4704835:rs752039628:rs76019453:rs6866758:5:156392653_CA_C",15]
["ENSG00000082515","MRPL22",5,154320630,154348971,1,"protein_coding",29093,"MRPL22",{"v":3.44167883429456e-07,"d":"3.44E-07"},0.276799402,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.7e-27,"d":"6.70E-27"},"rs4704819:rs76019453:rs4704830:rs6882345:rs4704835:rs752039628:rs6866758:5:156392653_CA_C",15]
["ENSG00000170624","SGCD",5,155297354,156194799,1,"protein_coding",6444,"SGCD",0.00233910042363156,0.319696283,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.7e-27,"d":"6.70E-27"},"rs76019453:rs4704819:rs4704830:rs6882345:rs4704835:rs752039628:rs6866758:5:156392653_CA_C:rs760614621",15]
["ENSG00000145850","TIMD4",5,156346293,156390266,-1,"protein_coding",91937,"TIMD4",{"v":4.33746964441321e-08,"d":"4.34E-08"},0.360934801,35,10.48,39,{"v":6.1249e-06,"d":"6.12E-06"},0.0123016,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops",{"v":6.7e-27,"d":"6.70E-27"},"rs76019453;rs4704830;rs6882345;rs4704835;rs752039628;rs6866758;5:156392653_CA_C;rs4704835:rs6866758:rs4704830",15]
["ENSG00000113249","HAVCR1",5,156456424,156486130,-1,"protein_coding",26762,"HAVCR1",0.00305433633416917,-0.160669209,84,9.969,132,{"v":2.75285E-18,"d":"2.75E-18"},{"v":5.93632e-22,"d":"5.94E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Coronary","+","Yes","Promoter_anchored_loops",{"v":6.7e-27,"d":"6.70E-27"},"rs4704835;rs4704830;rs6866758;rs6882345;5:156483396_CT_C;rs4704838;rs67960962;rs4704830:rs6866758:rs4704835",15]
["ENSG00000135077","HAVCR2",5,156512843,156569880,-1,"protein_coding",84868,"HAVCR2",0.111384118892431,0.940999528,0,0,23,{"v":5.31832e-05,"d":"5.32E-05"},0.000319789,"GTEx/v8/Artery_Aorta","-","No","NA",{"v":2.9e-13,"d":"2.90E-13"},"rs4704835",15]
["ENSG00000113272","THG1L",5,157158205,157168456,1,"protein_coding",54974,"THG1L",{"v":3.48304059537209e-05,"d":"3.48E-05"},1.451409669,0,0,1,0.000192414,{"v":3.05013e-08,"d":"3.05E-08"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":2.2e-10,"d":"2.20E-10"},"rs4704835",15]
["ENSG00000155858","LSM11",5,157170703,157187717,1,"protein_coding",134353,"LSM11",0.490844531335381,-1.362626757,0,0,2,{"v":2.44141e-05,"d":"2.44E-05"},0.00926856,"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":4.5e-08,"d":"4.50E-08"},"rs76019453",15]
["ENSG00000124568","SLC17A1",6,25783125,25832287,-1,"protein_coding",6568,"SLC17A1",{"v":2.59261497697838e-10,"d":"2.59E-10"},-0.181263012,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.4e-07,"d":"3.40E-07"},"rs1235162",16]
["ENSG00000124564","SLC17A3",6,25833294,25882514,-1,"protein_coding",10786,"SLC17A3",{"v":9.88205561287661e-14,"d":"9.88E-14"},-0.246502705,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":3e-08,"d":"3.00E-08"},"rs1235162",16]
["ENSG00000112337","SLC17A2",6,25912982,25930946,-1,"protein_coding",10246,"SLC17A2",0.00466985446742192,-0.129201002,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":5.8e-08,"d":"5.80E-08"},"rs1235162",16]
["ENSG00000112343","TRIM38",6,25963030,25987384,1,"protein_coding",10475,"TRIM38",{"v":4.75130205096512e-06,"d":"4.75E-06"},-0.220583262,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000124610","HIST1H1A",6,26017260,26018040,-1,"protein_coding",3024,"HIST1H1A",0.00353079926543669,-0.372206788,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000198366","HIST1H3A",6,26020718,26021186,1,"protein_coding",8350,"HIST1H3A",{"v":3.98008178767139e-05,"d":"3.98E-05"},-0.225706842,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000196176","HIST1H4A",6,26021907,26022278,1,"protein_coding",8359,"HIST1H4A",0.00228540295756206,0.434170117,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000124529","HIST1H4B",6,26027124,26027480,-1,"protein_coding",8366,"HIST1H4B",8.54182671998013E-3,0.166119276,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000124693","HIST1H3B",6,26031817,26032288,-1,"protein_coding",8358,"HIST1H3B",0.307282993148648,0.251696243,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000137259","HIST1H2AB",6,26033320,26033796,-1,"protein_coding",8335,"HIST1H2AB",0.00531944331445787,0.228134732,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000010704","HFE",6,26087509,26098571,1,"protein_coding",3077,"HFE",{"v":8.4969700310781e-07,"d":"8.50E-07"},0.210171656,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000197061","HIST1H4C",6,26104104,26104518,1,"protein_coding",8364,"HIST1H4C",{"v":8.85616839210981e-05,"d":"8.86E-05"},0.852191535,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000187475","HIST1H1T",6,26107640,26108364,-1,"protein_coding",3010,"HIST1H1T","NA",-0.068039131,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000158406","HIST1H4H",6,26281283,26285762,-1,"protein_coding",8365,"HIST1H4H",0.00879032933359599,1.05906941,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":5.8e-08,"d":"5.80E-08"},"rs1235162",16]
["ENSG00000182952","HMGN4",6,26538633,26546482,1,"protein_coding",10473,"HMGN4",0.557082341510099,-0.351002587,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000146109","ABT1",6,26597180,26600278,1,"protein_coding",29777,"ABT1",0.0271055673799205,0.104221009,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000181315","ZNF322",6,26636518,26659980,-1,"protein_coding",79692,"ZNF322","NA",-1.140467931,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000124635","HIST1H2BJ",6,27093676,27100541,-1,"protein_coding",8970,"HIST1H2BJ",0.47884211441258,0.308582046,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000196787","HIST1H2AG",6,27100832,27103070,1,"protein_coding",8969,"HIST1H2AG",0.000610464103704842,-0.741637225,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000197903","HIST1H2BK",6,27106073,27114619,-1,"protein_coding",85236,"HIST1H2BK",0.490754148427297,-0.043052263,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000198339","HIST1H4I",6,27107076,27108418,1,"protein_coding",8294,"HIST1H4I",0.446296012965993,-0.468005112,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000184825","HIST1H2AH",6,27114861,27115317,1,"protein_coding",85235,"HIST1H2AH",{"v":6.2950794420684e-05,"d":"6.30E-05"},0.194919981,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000112812","PRSS16",6,27215480,27224403,1,"protein_coding",10279,"PRSS16",{"v":2.23791834002529e-06,"d":"2.24E-06"},0.008848123,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.1e-09,"d":"4.10E-09"},"rs1235162",16]
["ENSG00000158553","POM121L2",6,27253682,27279949,-1,"protein_coding",94026,"POM121L2","NA",0.313408259,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4.1e-09,"d":"4.10E-09"},"rs1235162",16]
["ENSG00000124613","ZNF391",6,27342394,27371683,1,"protein_coding",346157,"ZNF391",{"v":9.25869403182407e-07,"d":"9.26E-07"},1.231716533,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.1e-09,"d":"4.10E-09"},"rs1235162",16]
["ENSG00000096654","ZNF184",6,27418522,27440897,-1,"protein_coding",7738,"ZNF184",0.133748635714874,-0.545662357,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000185130","HIST1H2BL",6,27775257,27775709,-1,"protein_coding",8340,"HIST1H2BL",0.00286755404850941,-0.03011099,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000196747","HIST1H2AI",6,27775899,27776429,1,"protein_coding",8329,"HIST1H2AI",0.581587114173739,-0.058326504,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000203813","HIST1H3H",6,27777842,27778314,1,"protein_coding",8357,"HIST1H3H",0.02493915563981,-0.177817416,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000182611","HIST1H2AJ",6,27782112,27782607,-1,"protein_coding",8331,"HIST1H2AJ",0.19119768143705,0.615053632,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000196374","HIST1H2BM",6,27782822,27783267,1,"protein_coding",8342,"HIST1H2BM",0.00275346435077864,-0.27562,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000197238","HIST1H4J",6,27791884,27792257,1,"protein_coding",8363,"HIST1H4J",0.423753830207411,0.598449973,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000197914","HIST1H4K",6,27798952,27799305,-1,"protein_coding",8362,"HIST1H4K",0.429118935200097,0.387416315,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000184348","HIST1H2AK",6,27805658,27806117,-1,"protein_coding",8330,"HIST1H2AK",0.0684285015781424,-0.04124411,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000233822","HIST1H2BN",6,27806323,27823487,1,"protein_coding",8341,"HIST1H2BN",0.139774615254902,0.145508408,0,0,80,{"v":2.60316E-5,"d":"2.60E-05"},0.00215173,"GTEx/v8/Artery_Aorta","+","Yes","Fetal_Cortex:GM12878",{"v":3e-08,"d":"3.00E-08"},"rs1235162",16]
["ENSG00000198374","HIST1H2AL",6,27833034,27833606,1,"protein_coding",8332,"HIST1H2AL",0.0624869158210738,-0.360341181,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000184357","HIST1H1B",6,27834570,27835359,-1,"protein_coding",3009,"HIST1H1B",0.509138756022723,-0.08989506,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000182572","HIST1H3I",6,27839623,27840099,-1,"protein_coding",8354,"HIST1H3I",0.360879945054601,-0.232438013,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000198558","HIST1H4L",6,27840926,27841289,-1,"protein_coding",8368,"HIST1H4L",0.191234624133278,0.426890108,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.1e-08,"d":"6.10E-08"},"rs1235162",16]
["ENSG00000197153","HIST1H3J",6,27858093,27860884,-1,"protein_coding",8356,"HIST1H3J",0.695883936820569,-0.189708056,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3e-08,"d":"3.00E-08"},"rs1235162",16]
["ENSG00000233224","HIST1H2AM",6,27860477,27860963,-1,"protein_coding",8336,"HIST1H2AM",0.000856482029037302,-0.225135146,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3e-08,"d":"3.00E-08"},"rs1235162",16]
["ENSG00000196331","HIST1H2BO",6,27861203,27861669,1,"protein_coding",8348,"HIST1H2BO",{"v":3.07277582735277E-5,"d":"3.07E-05"},-0.223062534,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3e-08,"d":"3.00E-08"},"rs1235162",16]
["ENSG00000168131","OR2B2",6,27878963,27880174,-1,"protein_coding",81697,"OR2B2",{"v":6.86720334316105e-05,"d":"6.87E-05"},-0.212076212,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000124657","OR2B6",6,27925019,27925960,1,"protein_coding",26212,"OR2B6",0.0407309275321611,-0.098173144,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000197279","ZNF165",6,28048753,28057341,1,"protein_coding",7718,"ZNF165",0.000563292029886091,0.227981468,0,0,187,{"v":1.60443E-6,"d":"1.60E-06"},{"v":1.94586E-12,"d":"1.95E-12"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000196812","ZSCAN16",6,28092338,28097860,1,"protein_coding",80345,"ZSCAN16",{"v":2.67303498489914e-06,"d":"2.67E-06"},0.184187397,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000198315","ZKSCAN8",6,28109688,28127250,1,"protein_coding",7745,"ZKSCAN8",2.31594506551783E-4,-0.142528224,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000137185","ZSCAN9",6,28192664,28201260,1,"protein_coding",7746,"ZSCAN9",{"v":4.10248860506101e-08,"d":"4.10E-08"},0.461166178,0,0,182,0.000108097,{"v":1.5619e-05,"d":"1.56E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","-","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000187626","ZKSCAN4",6,28212401,28227011,-1,"protein_coding",387032,"ZKSCAN4",{"v":6.74288454800845e-05,"d":"6.74E-05"},0.661631344,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000189134","NKAPL",6,28227098,28228736,1,"protein_coding",222698,"NKAPL",0.000165621301014734,0.051342603,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000235109","ZSCAN31",6,28292470,28324048,-1,"protein_coding",64288,"ZSCAN31",{"v":3.7712697083703e-09,"d":"3.77E-09"},1.107125092,0,0,115,{"v":1.41186e-05,"d":"1.41E-05"},{"v":4.37287e-25,"d":"4.37E-25"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","-","No","NA",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000189298","ZKSCAN3",6,28317691,28336947,1,"protein_coding",80317,"ZKSCAN3",0.000122608322341288,-0.65244291,0,0,115,{"v":5.36117E-6,"d":"5.36E-06"},{"v":4.57962e-07,"d":"4.58E-07"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","No","NA",{"v":1.9e-08,"d":"1.90E-08"},"rs1235162",16]
["ENSG00000158691","ZSCAN12",6,28346732,28367511,-1,"protein_coding",9753,"ZSCAN12",{"v":1.43991732878074E-5,"d":"1.44E-05"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000187987","ZSCAN23",6,28399707,28411279,-1,"protein_coding",222696,"ZSCAN23",0.00270295085017911,0.070656525,0,0,229,{"v":1.30476e-06,"d":"1.30E-06"},{"v":8.30529e-55,"d":"8.31E-55"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Mesenchymal_Stem_Cell",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000198704","GPX6",6,28471073,28495992,-1,"protein_coding",257202,"GPX6",{"v":3.13757952195529e-05,"d":"3.14E-05"},0.718702709,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000224586","GPX5",6,28493702,28502729,1,"protein_coding",2880,"GPX5",0.00888467745572368,0.354876486,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000232040","SCAND3",6,28539407,28583989,-1,"protein_coding",114821,"SCAND3",{"v":9.70724396864633e-09,"d":"9.71E-09"},-0.785031462,2,10.48,3,0.000192045,0.000305781,"GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204713","TRIM27",6,28870779,28891766,-1,"protein_coding",5987,"TRIM27",0.878751858118275,-0.142067713,14,18.69,4,{"v":9.05276e-05,"d":"9.05E-05"},{"v":9.5578e-15,"d":"9.56E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:GM12878:IMR90:Trophoblast-like_Cell:hESC",{"v":3.8e-08,"d":"3.80E-08"},"rs1235162",16]
["ENSG00000204709","C6orf100",6,28911654,28912314,1,"protein_coding",729583,"C6orf100","NA","NA",8,3.641,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Trophoblast-like_Cell:hESC",{"v":3.8e-08,"d":"3.80E-08"},"rs1235162",16]
["ENSG00000197935","ZNF311",6,28962562,28973093,-1,"protein_coding",282890,"ZNF311",0.000129446471411909,0.377857886,9,11.6,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204704","OR2W1",6,29011990,29013017,-1,"protein_coding",26692,"OR2W1",0.0865618905271982,0.531528388,7,6.576,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204703","OR2B3",6,29053985,29055090,-1,"protein_coding",442184,"OR2B3",1.3369321318042E-3,0.458839963,3,9.377,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204702","OR2J1",6,29068386,29069658,1,"protein_coding",442185,"OR2J1",0.0174945019459341,"NA",1,0.549,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204701","OR2J3",6,29079668,29080603,1,"protein_coding",442186,"OR2J3",0.0281435008681581,0.112859372,2,1.351,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204700","OR2J2",6,29141311,29142351,1,"protein_coding",26707,"OR2J2",0.0107267189301636,0.271259236,3,5.147,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":9.8e-09,"d":"9.80E-09"},"rs1235162",16]
["ENSG00000204695","OR14J1",6,29274403,29275519,1,"protein_coding",442191,"OR14J1",{"v":8.02406099709927e-08,"d":"8.02E-08"},1.335471591,3,6.748,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000243729","OR5V1",6,29323007,29399744,-1,"protein_coding",81696,"OR5V1",0.00344261897900665,0.32363506,8,11.39,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000112462","OR12D3",6,29341200,29343068,-1,"protein_coding",81797,"OR12D3",{"v":1.34136303903671e-05,"d":"1.34E-05"},0.883548764,3,11.39,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000168787","OR12D2",6,29364416,29365448,1,"protein_coding",26529,"OR12D2",0.601033125257784,0.457835329,3,6.779,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204694","OR11A1",6,29393281,29424848,-1,"protein_coding",26531,"OR11A1",0.0434844025575059,1.230255274,4,3.951,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000206474","OR10C1",6,29407083,29408731,1,"protein_coding",442194,"OR10C1",0.227592079399406,0.363897038,3,1.81,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204688","OR2H1",6,29424958,29432105,1,"protein_coding",26716,"OR2H1",0.0449040613109769,-0.358288136,4,3.951,0,"NA","NA","NA","NA","Yes","Spleen:Mesendoderm:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204687","MAS1L",6,29454474,29455738,-1,"protein_coding",116511,"MAS1L",0.000466205666114264,0.689547747,5,8.385,0,"NA","NA","NA","NA","Yes","Aorta:Liver:Pancreas:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000213886","UBD",6,29523292,29527702,-1,"protein_coding",10537,"UBD",0.0798957514124674,0.401530797,5,14.02,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204681","GABBR1",6,29523406,29601753,-1,"protein_coding",2550,"GABBR1",0.999969901472702,0.238892484,10,14.02,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000204657","OR2H2",6,29555683,29556745,1,"protein_coding",7932,"OR2H2",0.0899459247726437,0.69683603,4,3.904,257,{"v":1.16286e-09,"d":"1.16E-09"},{"v":1.93261E-11,"d":"1.93E-11"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4e-09,"d":"4.00E-09"},"rs1235162",16]
["ENSG00000112514","CUTA",6,33384219,33386094,-1,"protein_coding",51596,"CUTA",{"v":1.14218167340545E-5,"d":"1.14E-05"},-0.619995669,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.7e-10,"d":"1.70E-10"},"rs114863007;rs59136961:rs114863007",17]
["ENSG00000197283","SYNGAP1",6,33387847,33421466,1,"protein_coding",8831,"SYNGAP1",0.999998449747972,-1.109120657,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.7e-10,"d":"1.70E-10"},"rs114863007;rs59136961:rs114863007",17]
["ENSG00000204188","GGNBP1",6,33551515,33556803,1,"protein_coding",449520,"GGNBP1","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.8e-11,"d":"6.80E-11"},"rs114863007;rs59136961:rs114863007:rs59136961",17]
["ENSG00000137288","UQCC2",6,33662070,33679504,-1,"protein_coding",84300,"UQCC2",0.0595477327271092,0.254207876,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.7e-10,"d":"1.70E-10"},"rs114863007;rs59136961:rs114863007",17]
["ENSG00000161896","IP6K3",6,33689444,33714762,-1,"protein_coding",117283,"IP6K3",0.0485338526527661,1.72324211,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-10,"d":"1.40E-10"},"rs114863007;rs59136961:rs59136961:rs114863007",17]
["ENSG00000161904","LEMD2",6,33738979,33756913,-1,"protein_coding",221496,"LEMD2",0.302373361272148,0.392920076,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":4.2e-11,"d":"4.20E-11"},"rs59136961:rs114863007",17]
["ENSG00000096395","MLN",6,33762450,33771788,-1,"protein_coding",4295,"MLN",0.00165857384360036,0.983257947,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.4e-10,"d":"1.40E-10"},"rs59136961:rs114863007",17]
["ENSG00000124493","GRM4",6,33989628,34123399,-1,"protein_coding",2914,"GRM4",0.979350085369263,-0.635218754,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":6.8e-11,"d":"6.80E-11"},"rs59136961:rs114863007;rs59136961:rs114863007:rs3822921",17]
["ENSG00000186577","C6orf1",6,34214157,34217247,-1,"protein_coding",221491,"C6orf1",0.29871864309512,-0.83430399,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":6.8e-11,"d":"6.80E-11"},"rs36018387;rs3822921:rs59136961:rs114863007;rs59136961:rs114863007",17]
["ENSG00000272325","NUDT3",6,34247456,34360451,-1,"protein_coding",11165,"NUDT3",0.876816622471426,0.134938478,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.2e-11,"d":"4.20E-11"},"rs59136961:rs114863007;rs59136961:rs114863007:rs36018387;rs3822921:rs79834165:rs3822921:rs36018387;rs114863007;rs3822921:rs151060048",17]
["ENSG00000270800","RPS10-NUDT3",6,34256547,34393825,-1,"protein_coding",100529239,"RPS10-NUDT3","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4e-10,"d":"1.40E-10"},"rs114863007;rs59136961:rs59136961:rs114863007:rs36018387;rs3822921:rs36018387;rs3822921:rs3822921",17]
["ENSG00000124614","RPS10",6,34385231,34393902,-1,"protein_coding",6204,"RPS10",0.946462997504496,0.20471765,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4e-10,"d":"1.40E-10"},"rs114863007;rs59136961:rs59136961:rs114863007:rs36018387;rs3822921:rs36018387;rs3822921:rs3822921",17]
["ENSG00000124507","PACSIN1",6,34433916,34503006,1,"protein_coding",29993,"PACSIN1",0.991339222233708,-1.593899928,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.6e-11,"d":"6.60E-11"},"rs114863007;rs59136961:rs59136961:rs114863007:rs151060048:rs3822921:rs36018387;rs3822921:rs36018387;rs3822921:rs79834165",17]
["ENSG00000124664","SPDEF",6,34505579,34524110,-1,"protein_coding",25803,"SPDEF",0.711825442176907,-0.407039982,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4e-10,"d":"1.40E-10"},"rs114863007;rs59136961:rs59136961:rs114863007:rs3822921:rs36018387;rs3822921:rs36018387;rs3822921",17]
["ENSG00000196821","C6orf106",6,34555065,34664636,-1,"protein_coding",64771,"C6orf106",0.454029671085684,-1.135549043,46,14.17,105,{"v":1.00433e-18,"d":"1.00E-18"},{"v":2.73886e-27,"d":"2.74E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3e-12,"d":"1.30E-12"},"rs114863007;rs59136961;rs151060048;rs79834165;rs3822921;rs36018387;rs36110421;rs59136961:rs114863007:rs59136961:rs151060048:rs3822921:rs36018387;rs3822921:rs36018387",17]
["ENSG00000124562","SNRPC",6,34725183,34741571,1,"protein_coding",6631,"SNRPC",0.727261777653869,-0.351120295,17,15.81,106,{"v":4.04616e-11,"d":"4.05E-11"},{"v":1.95691e-18,"d":"1.96E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.2e-11,"d":"4.20E-11"},"rs59136961;rs114863007;rs79834165;rs36018387;rs3822921;rs59136961:rs114863007;rs59136961:rs114863007:rs3822921:rs36018387;rs3822921:rs36018387",17]
["ENSG00000065060","UHRF1BP1",6,34759857,34850915,1,"protein_coding",54887,"UHRF1BP1",{"v":2.46541297366596e-07,"d":"2.47E-07"},-0.83035352,43,15.05,106,{"v":4.65612E-22,"d":"4.66E-22"},{"v":1.98454e-106,"d":"1.98E-106"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3e-12,"d":"1.30E-12"},"rs59136961;rs114863007;rs3822921;rs36018387;rs79834165;rs59136961:rs36018387;rs3822921:rs114863007;rs59136961:rs114863007:rs151060048:rs3822921:rs36018387;rs3822921:rs79834165",17]
["ENSG00000064995","TAF11",6,34845555,34855866,-1,"protein_coding",6882,"TAF11",0.875431936618392,-0.232568972,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.2e-11,"d":"4.20E-11"},"rs59136961:rs114863007;rs59136961:rs114863007:rs36018387;rs3822921:rs3822921:rs79834165:rs36018387;rs114863007;rs3822921:rs151060048",17]
["ENSG00000064999","ANKS1A",6,34857042,35059179,1,"protein_coding",23294,"ANKS1A",0.84685967793139,0.260682535,5,9.165,2,{"v":3.87368e-06,"d":"3.87E-06"},{"v":1.86319E-5,"d":"1.86E-05"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.2e-11,"d":"4.20E-11"},"rs79834165;rs3822921;rs36110421;rs59136961:rs114863007;rs59136961:rs114863007:rs36018387;rs3822921:rs3822921:rs79834165:rs36018387;rs114863007;rs3822921:rs151060048",17]
["ENSG00000124678","TCP11",6,35085848,35116387,-1,"protein_coding",6954,"TCP11",{"v":4.00945484653237e-05,"d":"4.01E-05"},-0.41353592,2,2.993,1,1.05319E-4,{"v":3.04249E-22,"d":"3.04E-22"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Adult_Cortex:Aorta:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.2e-11,"d":"4.20E-11"},"rs3822921;rs36110421;rs59136961:rs79834165:rs36018387;rs114863007;rs3822921:rs36018387;rs3822921:rs114863007;rs59136961:rs114863007:rs151060048:rs3822921:rs36110421",17]
["ENSG00000146197","SCUBE3",6,35182190,35220856,1,"protein_coding",222663,"SCUBE3",0.9999837065276,-0.692415276,1,13,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Lung:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.2e-11,"d":"4.20E-11"},"rs36018387;rs3822921;rs59136961:rs114863007;rs59136961:rs114863007:rs3822921:rs79834165:rs151060048:rs36018387",17]
["ENSG00000065029","ZNF76",6,35226686,35263762,1,"protein_coding",7629,"ZNF76",{"v":5.07288621916122e-16,"d":"5.07E-16"},0.397539219,1,26.5,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-10,"d":"1.40E-10"},"rs79834165;rs59136961:rs79834165:rs3822921:rs36018387;rs114863007;rs3822921:rs36018387;rs3822921:rs114863007;rs59136961:rs114863007",17]
["ENSG00000023892","DEF6",6,35265595,35289548,1,"protein_coding",50619,"DEF6",0.976824149100722,0.153810841,1,26.5,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":9.8e-07,"d":"9.80E-07"},"rs79834165;rs59136961",17]
["ENSG00000112033","PPARD",6,35310335,35395968,1,"protein_coding",5467,"PPARD",0.966868134632325,0.253948931,1,1.155,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":1.3e-12,"d":"1.30E-12"},"rs36018387;rs36018387:rs3822921",17]
["ENSG00000112039","FANCE",6,35420138,35434880,1,"protein_coding",2178,"FANCE",0.00313889923167915,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.3e-12,"d":"1.30E-12"},"rs36018387",17]
["ENSG00000112041","TULP1",6,35465651,35480715,-1,"protein_coding",7287,"TULP1",0.80790432015979,-0.139076605,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.2e-06,"d":"1.20E-06"},"rs59136961",17]
["ENSG00000096060","FKBP5",6,35541362,35696360,-1,"protein_coding",2289,"FKBP5",0.498849476622916,-0.767039177,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.7e-10,"d":"1.70E-10"},"rs114863007;rs59136961:rs114863007:rs36018387;rs3822921",17]
["ENSG00000137392","CLPS",6,35762759,35765088,-1,"protein_coding",1208,"CLPS",0.0562747598072514,0.768244845,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":6.1e-08,"d":"6.10E-08"},"rs59136961:rs114863007;rs59136961",17]
["ENSG00000156711","MAPK13",6,36095586,36107842,1,"protein_coding",5603,"MAPK13",{"v":5.48349848830244E-7,"d":"5.48E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.4e-10,"d":"3.40E-10"},"rs36018387;rs3822921",17]
["ENSG00000112079","STK38",6,36461669,36515247,-1,"protein_coding",11329,"STK38",0.853295086026932,-0.412586124,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.7e-10,"d":"1.70E-10"},"rs114863007;rs59136961:rs114863007",17]
["ENSG00000196591","HDAC2",6,114254192,114332472,-1,"protein_coding",3066,"HDAC2",0.999390588066461,-3.030737984,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000249853","HS3ST5",6,114376750,114664209,-1,"protein_coding",222537,"HS3ST5",0.569245912900789,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000111816","FRK",6,116252312,116381921,-1,"protein_coding",2444,"FRK",{"v":6.59374622255819e-10,"d":"6.59E-10"},2.58876413,15,19.86,22,{"v":1.24919e-10,"d":"1.25E-10"},{"v":2.91314e-17,"d":"2.91E-17"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000178425","NT5DC1",6,116422012,116570660,1,"protein_coding",221294,"NT5DC1",0.326411116423151,-0.101658908,5,14.54,24,{"v":7.40908e-09,"d":"7.41E-09"},{"v":1.41242E-18,"d":"1.41E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Adult_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000123500","COL10A1",6,116440086,116479910,-1,"protein_coding",1300,"COL10A1",{"v":6.35839564298384e-05,"d":"6.36E-05"},-0.141903212,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:hESC",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000187189","TSPYL4",6,116571151,116575261,-1,"protein_coding",23270,"TSPYL4",2.61866598258138E-3,0.28308504,0,0,16,{"v":1.03439e-05,"d":"1.03E-05"},1.18885E-4,"GTEx/v8/Heart_Left_Ventricle","+","Yes","GM12878:Mesenchymal_Stem_Cell:hESC",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000111817","DSE",6,116575336,116762424,1,"protein_coding",29940,"DSE",0.385415297078461,1.399470369,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell:hESC",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000173626","TRAPPC3L",6,116816152,116866773,-1,"protein_coding",100128327,"TRAPPC3L","NA",-0.063711938,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000178033","FAM26E",6,116832809,116845955,1,"protein_coding",254228,"FAM26E",0.00110838835995408,2.210740591,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000164451","FAM26D",6,116850174,116880031,1,"protein_coding",221301,"FAM26D",0.0338388220536114,0.383426399,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000111832","RWDD1",6,116892530,116918838,1,"protein_coding",51389,"RWDD1",0.372943967483844,1.003605814,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000111834","RSPH4A",6,116937642,116954148,1,"protein_coding",345895,"RSPH4A",{"v":1.84090351392863e-07,"d":"1.84E-07"},-0.031379642,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000196911","KPNA5",6,117002350,117063029,1,"protein_coding",3841,"KPNA5",1.22321535722017E-3,-1.643885368,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000183807","FAM162B",6,117073363,117086886,-1,"protein_coding",221303,"FAM162B",0.000825834892494331,-0.499487886,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000185002","RFX6",6,117198375,117253326,1,"protein_coding",222546,"RFX6",0.0300465226013637,0.022429681,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.8e-08,"d":"2.80E-08"},"rs6934962",18]
["ENSG00000111860","CEP85L",6,118781935,119031238,-1,"protein_coding",387119,"CEP85L",0.00496390705689714,0.298569554,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":3.7E-8,"d":"3.70E-08"},"rs6934962",18]
["ENSG00000130363","RSPH3",6,159393903,159421219,-1,"protein_coding",83861,"RSPH3",0.00139623159251261,-0.228791289,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7.4e-19,"d":"7.40E-19"},"rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs143843429:rs117379529",19]
["ENSG00000164694","FNDC1",6,159590429,159693141,1,"protein_coding",84624,"FNDC1",{"v":3.07460719768204e-07,"d":"3.07E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs11481286:rs3777420:rs7750288:rs6932293;rs11481286:rs9457827:rs2065397:rs3777411:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs9295128;rs117733303:rs9355288:rs998075:rs648253:rs4709393:rs386453:rs117733303:rs4708870:rs9295128",19]
["ENSG00000112096","SOD2",6,160090089,160183561,-1,"protein_coding",6648,"SOD2",0.237154646295316,1.737932652,0,0,4,{"v":2.73697e-06,"d":"2.74E-06"},0.00366842,"GTEx/v8/Artery_Tibial","+","Yes","Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-32,"d":"2.50E-32"},"6:160560880_CATG_C;rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs9457827:rs2065397:rs3777411:rs80254170:rs998075:rs648253:rs4709393:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs117733303:rs4708870:rs117379529",19]
["ENSG00000146457","WTAP",6,160146617,160177351,1,"protein_coding",9589,"WTAP",0.995576734722068,1.745772008,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell:hESC",{"v":1.1e-18,"d":"1.10E-18"},"rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs9355288",19]
["ENSG00000120437","ACAT2",6,160181360,160200144,1,"protein_coding",39,"ACAT2",{"v":1.26453863126978e-05,"d":"1.26E-05"},0.731905322,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-32,"d":"2.50E-32"},"rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs9457827:rs2065397:rs3777411:rs80254170:rs998075:rs648253:rs4709393:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs117733303:rs4708870:rs117379529",19]
["ENSG00000120438","TCP1",6,160199530,160210781,-1,"protein_coding",6950,"TCP1",0.989085751892209,0.157899873,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs9295128;rs117733303:rs9355288:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453:rs117733303:rs4708870:rs143843429:rs9295128",19]
["ENSG00000112110","MRPL18",6,160210844,160219468,1,"protein_coding",29074,"MRPL18",0.000794102804498299,1.581628342,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs9295128;rs117733303:rs9355288:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453:rs117733303:rs4708870:rs143843429:rs9295128",19]
["ENSG00000146453","PNLDC1",6,160221298,160241736,1,"protein_coding",154197,"PNLDC1",{"v":2.5447781123909e-08,"d":"2.54E-08"},0.054243557,1,6.927,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs11481286;rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs9295128;rs117733303:rs9355288:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453:rs117733303:rs4708870:rs143843429:rs9295128",19]
["ENSG00000130368","MAS1",6,160327974,160329108,1,"protein_coding",4142,"MAS1",0.000870823408355688,-0.186942489,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-32,"d":"2.50E-32"},"rs3777420:rs9457827:rs6932293;rs11481286:rs2065397:rs3777411:rs80254170:rs7750288:rs11481286:rs9295128;rs117733303:rs9355288:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs998075:rs648253:rs4709393:rs386453:rs117733303:rs4708870:rs55730499:rs6938647",19]
["ENSG00000197081","IGF2R",6,160390131,160534539,1,"protein_coding",3482,"IGF2R",0.999999196216303,-0.312060143,116,23.4,15,{"v":3.23942E-9,"d":"3.24E-09"},{"v":4.7206200000000004E-18,"d":"4.72E-18"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs3777420;rs7750288;rs6932293;rs11481286;rs9457827;rs998075;rs648253;rs4709393;rs3777411;rs2065397;rs80254170;rs12208357;6:160560880_CATG_C;rs3777420:rs7750288:rs6932293;rs11481286:rs9355288:rs11481286:rs386453:rs9457827:rs998075:rs648253:rs4709393:rs3777411:rs2065397:rs80254170:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs117733303:rs4708870:rs9295128;rs117733303:rs143843429:rs117379529:rs9295128:rs55730499:rs6938647",19]
["ENSG00000175003","SLC22A1",6,160542821,160579750,1,"protein_coding",6580,"SLC22A1",{"v":1.23977716739769e-13,"d":"1.24E-13"},-0.158083671,17,23.4,69,{"v":5.41977e-14,"d":"5.42E-14"},{"v":3.85687e-11,"d":"3.86E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs6932293;6:160560880_CATG_C;rs12208357;rs4646272;rs3798167;rs13211753;rs9457827;rs11481286;rs998075;rs2065397;rs9295128:rs386453:rs9295128;rs117733303:rs9355288:rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs117733303:rs4708870:rs9457827:rs2065397:rs3777411:rs80254170:6:160560880_CATG_C:rs3798167:rs13211753:rs16891156:rs998075:rs648253:rs4709393:rs3903279:rs55730499:rs6938647",19]
["ENSG00000112499","SLC22A2",6,160592093,160698670,-1,"protein_coding",6582,"SLC22A2",{"v":1.4191712191388E-9,"d":"1.42E-09"},0.905296138,23,8.19,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs13211753;rs16891156;rs3903279;rs9295128;rs386453;rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs386453:rs9295128;rs117733303:rs9355288:rs9295128:rs3798167:rs13211753:rs16891156",19]
["ENSG00000146477","SLC22A3",6,160769300,160876014,1,"protein_coding",6581,"SLC22A3",{"v":3.31638540911901E-5,"d":"3.32E-05"},0.310629054,25,6.912,23,{"v":1.04917E-18,"d":"1.05E-18"},{"v":7.34452e-14,"d":"7.34E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Psoas:Right_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.1e-35,"d":"8.10E-35"},"rs9295128;rs386453;rs117733303;rs9355288;rs3798167;rs3777420:rs12208357;rs80254170:rs6932293:6:160560880_CATG_C:rs12208357:rs4646272:rs9295128;rs117733303:rs9355288:rs9457827:rs6932293;rs11481286:rs998075:rs648253:rs4709393:rs3777411:rs13211753:rs16891156:rs3903279:rs9295128:rs386453:rs7750288:rs11481286:rs3798167:rs2065397:rs80254170:rs117733303:rs4708870",19]
["ENSG00000198670","LPA",6,160952515,161087407,-1,"protein_coding",4018,"LPA",{"v":2.4422277924849E-32,"d":"2.44E-32"},0.042144435,8,9.933,20,{"v":7.38964e-09,"d":"7.39E-09"},1.04571E-4,"GTEx/v8/Liver","-","No","NA",{"v":2.5e-32,"d":"2.50E-32"},"rs55730499;rs6938647;rs56393506;rs9295128;rs117733303;rs9355288",19]
["ENSG00000122194","PLG",6,161123270,161174347,1,"protein_coding",5340,"PLG",0.00243511733948206,0.479258267,61,11.99,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4e-29,"d":"1.40E-29"},"rs55730499;rs139399782;rs1782629;rs74625856;rs139399782:rs74625856:rs1782629:rs9295128;rs117733303:rs9355288:rs10214652:rs143843429:rs117379529",19]
["ENSG00000085511","MAP3K4",6,161412759,161538417,1,"protein_coding",4216,"MAP3K4",0.999991910638856,"NA",3,4.019,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.7e-20,"d":"5.70E-20"},"rs143843429;rs117379529;rs139399782:rs74625856:rs1782629:rs10214652:rs143843429:rs117379529",19]
["ENSG00000026652","AGPAT4",6,161551011,161695093,-1,"protein_coding",56895,"AGPAT4",0.674499951839515,0.748253089,3,2.537,2,{"v":8.65824e-06,"d":"8.66E-06"},0.0238264,"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Hippocampus:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.7e-20,"d":"5.70E-20"},"rs117379529;rs143843429;rs143843429:rs139399782:rs117379529:rs9355288:rs74625856:rs1782629:rs10214652:rs55730499",19]
["ENSG00000185345","PARK2",6,161768452,163148803,-1,"protein_coding",5071,"PARK2",0.0218088318211922,0.549835313,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":8.1e-35,"d":"8.10E-35"},"rs143843429:rs10214652:rs117379529:rs139399782:rs74625856:rs1782629:rs9295128:rs386453:rs9295128;rs117733303:rs9355288:rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs117733303:rs4708870:rs55730499:rs6938647",19]
["ENSG00000112530","PACRG",6,163148164,163736524,1,"protein_coding",135138,"PACRG",0.000104676937493315,0.454746473,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Aorta:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":8.1e-35,"d":"8.10E-35"},"rs143843429:rs10214652:rs117379529:rs139399782:rs74625856:rs1782629:rs9295128:rs386453:rs9295128;rs117733303:rs9355288:rs3777420:rs7750288:rs6932293;rs11481286:rs11481286:rs117733303:rs4708870:rs55730499:rs6938647",19]
["ENSG00000225683","AL078585.1",6,163586446,163612840,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.7e-20,"d":"5.70E-20"},"rs55730499:rs139399782:rs1782629:rs74625856:rs10214652:rs143843429:rs117379529",19]
["ENSG00000112531","QKI",6,163835032,163999628,1,"protein_coding",9444,"QKI",0.963163356453829,-0.183477081,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.7e-26,"d":"1.70E-26"},"rs55730499:rs143843429:rs117379529:rs139399782:rs74625856:rs1782629:rs10214652",19]
["ENSG00000196313","POM121",7,72349936,72421979,1,"protein_coding",9883,"POM121","NA",-1.370618997,0,0,59,{"v":8.97114e-08,"d":"8.97E-08"},{"v":1.50688E-66,"d":"1.51E-66"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":5.2E-23,"d":"5.20E-23"},"rs35348663;rs34121855;rs42122;7:73042302_GCTTT_G;rs35348663:7:73042302_GCTTT_G;rs42122:rs34121855:rs42122:rs35489648:7:72840443_CT_C:7:73042302_GCTTT_G",20]
["ENSG00000155428","TRIM74",7,72430016,72439997,-1,"protein_coding",378108,"TRIM74",0.780333820359187,-0.947438302,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-19,"d":"2.20E-19"},"7:73042302_GCTTT_G;rs42122:rs35489648:rs34121855",20]
["ENSG00000130305","NSUN5",7,72716514,72722864,-1,"protein_coding",55695,"NSUN5",{"v":1.45415268581091e-06,"d":"1.45E-06"},-0.276519006,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.5E-22,"d":"1.50E-22"},"7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:rs35348663:7:73042302_GCTTT_G:7:72840443_CT_C:rs42122:rs35489648:rs34121855",20]
["ENSG00000146755","TRIM50",7,72726535,72742085,-1,"protein_coding",135892,"TRIM50",{"v":2.72561665019464E-6,"d":"2.73E-06"},-0.790238603,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":9.3e-21,"d":"9.30E-21"},"rs42122:rs35489648:7:72840443_CT_C:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G;rs35489648:rs34121855;rs35348663:rs34121855:rs35348663",20]
["ENSG00000077800","FKBP6",7,72742167,72772634,1,"protein_coding",8468,"FKBP6",0.13060063873413,-0.33452228,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":9.3e-21,"d":"9.30E-21"},"rs42122:rs35489648:7:72840443_CT_C:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G;rs35489648:rs34121855;rs35348663:rs34121855:rs35348663",20]
["ENSG00000188763","FZD9",7,72848109,72850450,1,"protein_coding",8326,"FZD9","NA","NA",7,3.057,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.3e-21,"d":"9.30E-21"},"rs42122;7:72840443_CT_C;7:73042302_GCTTT_G;rs35489648;rs34121855;rs35348663;rs42122:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:rs35348663:rs34121855",20]
["ENSG00000009954","BAZ1B",7,72854728,72936608,-1,"protein_coding",9031,"BAZ1B",0.999999562861573,-1.106984422,36,8.812,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-22,"d":"1.50E-22"},"7:73042302_GCTTT_G;rs35489648;rs42122;rs34121855;rs35348663;rs35348663:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:rs34121855:7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G:7:72840443_CT_C:rs42122:rs35489648",20]
["ENSG00000106635","BCL7B",7,72950686,72972332,-1,"protein_coding",9275,"BCL7B",0.706637383924404,-0.386261382,15,14.54,67,{"v":2.54871e-06,"d":"2.55E-06"},{"v":3.40292E-13,"d":"3.40E-13"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.2E-23,"d":"5.20E-23"},"rs35348663;7:73042302_GCTTT_G;rs42122;rs34121855;rs35489648;rs35348663:7:73042302_GCTTT_G",20]
["ENSG00000106638","TBL2",7,72983262,72993121,-1,"protein_coding",26608,"TBL2",0.00437650656905421,8.921304858,31,10.3,51,{"v":1.29213e-05,"d":"1.29E-05"},{"v":4.93874e-46,"d":"4.94E-46"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops",{"v":7.1e-22,"d":"7.10E-22"},"rs34121855;rs35348663;7:73042302_GCTTT_G;rs42122;rs35489648;rs799161",20]
["ENSG00000009950","MLXIPL",7,73007524,73038873,-1,"protein_coding",51085,"MLXIPL",0.676823094036297,0.477223974,75,19.09,136,{"v":5.28937e-28,"d":"5.29E-28"},{"v":1.10979e-22,"d":"1.11E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex",{"v":5.2E-23,"d":"5.20E-23"},"rs34121855;rs35348663;rs35489648;7:73042302_GCTTT_G;rs42122;rs799169;rs799168;7:73047677_GT_G;rs799161;rs42122:7:73042302_GCTTT_G:rs34121855;rs35348663:rs34121855",20]
["ENSG00000176428","VPS37D",7,73082155,73086442,1,"protein_coding",155382,"VPS37D",0.656347210550458,"NA",0,0,54,{"v":2.29153E-10,"d":"2.29E-10"},{"v":1.34286e-08,"d":"1.34E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":5.2E-23,"d":"5.20E-23"},"rs34121855;rs35348663;7:73042302_GCTTT_G;rs799169;rs799168;rs799161;rs35348663:rs34121855;rs35348663:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs35489648:rs34121855:rs34121855",20]
["ENSG00000106089","STX1A",7,73113536,73134002,-1,"protein_coding",6804,"STX1A",0.910475757164848,-0.07051921,0,0,1,0.000203054,{"v":1.22792E-16,"d":"1.23E-16"},"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":1.5E-22,"d":"1.50E-22"},"rs799161;rs34121855;rs35348663:7:73042302_GCTTT_G",20]
["ENSG00000106077","ABHD11",7,73150424,73153197,-1,"protein_coding",83451,"ABHD11",{"v":9.03291221619057e-06,"d":"9.03E-06"},0.148517676,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.8e-23,"d":"6.80E-23"},"7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs34121855;rs35348663:rs35489648:rs34121855:rs34121855",20]
["ENSG00000165215","CLDN3",7,73183328,73184600,-1,"protein_coding",1365,"CLDN3",0.678537320145956,-0.798792708,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":6.8e-23,"d":"6.80E-23"},"rs34121855",20]
["ENSG00000165171","WBSCR27",7,73248920,73256865,-1,"protein_coding",155368,"WBSCR27",0.0679116625114122,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-21,"d":"1.00E-21"},"rs35348663:rs34121855;rs35348663:7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs35489648",20]
["ENSG00000175877","WBSCR28",7,73275489,73280223,1,"protein_coding",135886,"WBSCR28",{"v":1.58800503099146E-6,"d":"1.59E-06"},0.424364093,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.2e-20,"d":"2.20E-20"},"rs34121855;rs35348663:7:73042302_GCTTT_G;rs42122",20]
["ENSG00000106683","LIMK1",7,73497263,73536855,1,"protein_coding",3984,"LIMK1",0.990896287164463,-0.781218183,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.5E-22,"d":"1.50E-22"},"7:73042302_GCTTT_G;rs35489648:7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:7:73042302_GCTTT_G",20]
["ENSG00000106682","EIF4H",7,73588575,73611431,1,"protein_coding",7458,"EIF4H",0.922544880243499,-1.500430355,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":9.9e-22,"d":"9.90E-22"},"7:73042302_GCTTT_G;rs42122:7:73042302_GCTTT_G:rs34121855;rs35348663",20]
["ENSG00000086730","LAT2",7,73613982,73644161,1,"protein_coding",7462,"LAT2",0.000691063098880473,-0.479096813,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.4e-21,"d":"2.40E-21"},"rs799169:rs799168:rs799169;rs799168:7:73042302_GCTTT_G:rs34121855:rs799161",20]
["ENSG00000049541","RFC2",7,73645829,73668774,-1,"protein_coding",5982,"RFC2",{"v":4.04212746398499e-05,"d":"4.04E-05"},-0.396975582,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.5e-20,"d":"1.50E-20"},"7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663",20]
["ENSG00000106665","CLIP2",7,73703805,73820273,1,"protein_coding",7461,"CLIP2",0.999881647285659,0.2522342,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.5E-22,"d":"1.50E-22"},"7:73042302_GCTTT_G;rs42122:rs34121855;rs35348663:7:73042302_GCTTT_G",20]
["ENSG00000198129","DEFB107B",8,7353368,7366833,1,"protein_coding",503614,"DEFB107B","NA",-0.203867911,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.4E-8,"d":"2.40E-08"},"rs2976940",21]
["ENSG00000182319","SGK223",8,8175258,8244008,-1,"protein_coding",157285,"PRAG1",{"v":5.12369052262778e-20,"d":"5.12E-20"},"NA",9,18.02,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.9e-08,"d":"1.90E-08"},"rs2976940",21]
["ENSG00000253958","CLDN23",8,8559448,8561616,1,"protein_coding",137075,"CLDN23",{"v":2.46842024128337E-5,"d":"2.47E-05"},1.939020665,0,0,6,{"v":3.82989e-06,"d":"3.83E-06"},{"v":1.33858E-5,"d":"1.34E-05"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":6.7e-09,"d":"6.70E-09"},"rs2976940;rs4240623;rs11774915",21]
["ENSG00000147324","MFHAS1",8,8640864,8751155,-1,"protein_coding",9258,"MFHAS1",{"v":2.22820045783843E-5,"d":"2.23E-05"},0.9551839,0,0,12,{"v":8.24532e-11,"d":"8.25E-11"},{"v":2.21586E-22,"d":"2.22E-22"},"GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-35,"d":"1.20E-35"},"rs2976940;rs11779019;rs9772631:rs4240623:rs2126259;rs12546198:rs2976940:rs10099512:rs2126259:rs2126259;rs10099512:rs34290760:rs11774915:rs10102271",21]
["ENSG00000104626","ERI1",8,8859657,8974256,1,"protein_coding",90459,"ERI1",0.000454685197816091,0.949360106,0,0,59,{"v":7.26387e-08,"d":"7.26E-08"},{"v":1.19077e-06,"d":"1.19E-06"},"GTEx/v8/Artery_Aorta:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-35,"d":"1.20E-35"},"rs2976940;rs2126259;rs11774915;rs12546198;rs11779019;rs2976940:rs10099512:rs2126259:rs4240623:rs9772631:rs34290760:rs11774915:rs2126259;rs12546198:rs10102271:8:9220256_CT_C:rs922049:rs12546198:rs12546198;rs11786900:rs11779019:rs6601599;rs11250098:rs2126259;rs10099512:rs10102352:rs7846549:rs11786900:rs11786900;rs7846549","21:22:00"]
["ENSG00000173281","PPP1R3B",8,8993765,9009084,-1,"protein_coding",79660,"PPP1R3B",0.0229191412335762,3.70852971,0,0,28,{"v":2.03833e-08,"d":"2.04E-08"},{"v":2.14339E-8,"d":"2.14E-08"},"GTEx/v8/Artery_Tibial","-","Yes","Mesendoderm",{"v":1.2e-35,"d":"1.20E-35"},"rs2976940;rs922049;rs9772631:rs10099512:rs2126259:rs2126259;rs10099512:rs4240623:rs34290760:rs11774915:rs2126259;rs12546198:rs10102271",21]
["ENSG00000253426","RP11-10A14.4",8,9009252,9025646,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.2e-35,"d":"1.20E-35"},"rs9772631:rs10099512:rs2126259:rs2126259;rs10099512:rs4240623:rs34290760:rs11774915:rs2126259;rs12546198:rs10102271",21]
["ENSG00000173273","TNKS",8,9413424,9639856,1,"protein_coding",8658,"TNKS",0.777115954184058,1.637267498,0,0,13,{"v":7.43105e-08,"d":"7.43E-08"},0.00127623,"GTEx/v8/Liver","+","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-35,"d":"1.20E-35"},"rs2126259;rs12546198;rs2976940:rs11786900;rs7846549:rs11779019:rs9772631:rs10099512:rs2126259:rs2126259;rs10099512:rs4240623:rs34290760:rs11774915:rs2126259;rs12546198:rs10102271:rs10102352:8:9220256_CT_C:rs922049:rs12546198:rs12546198;rs11786900:rs7846549:rs11786900",21]
["ENSG00000175806","MSRA",8,9911778,10286401,1,"protein_coding",4482,"MSRA",{"v":1.69976100303061E-6,"d":"1.70E-06"},0.601529643,58,18.39,27,{"v":4.3643e-06,"d":"4.36E-06"},{"v":1.77758E-6,"d":"1.78E-06"},"GTEx/v8/Artery_Tibial","+","Yes","IMR90",{"v":2.1e-09,"d":"2.10E-09"},"rs17155393;rs615632;rs7005363;rs11250098;rs4240674","21:22:00"]
["ENSG00000183638","RP1L1",8,10463859,10569697,-1,"protein_coding",94137,"RP1L1","NA",1.244966111,0,0,173,{"v":4.49213e-08,"d":"4.49E-08"},{"v":5.58954e-13,"d":"5.59E-13"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","IMR90",{"v":1.8e-08,"d":"1.80E-08"},"rs11250098;rs6601599;rs2467519;rs11250098:rs6601599",22]
["ENSG00000171060","C8orf74",8,10530147,10558103,1,"protein_coding",203076,"C8orf74",{"v":1.01040579381024E-11,"d":"1.01E-11"},0.574612154,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.9e-06,"d":"2.90E-06"},"rs6601599;rs11250098",22]
["ENSG00000171056","SOX7",8,10581278,10697357,-1,"protein_coding",83595,"SOX7",0.131241610927833,0.638029508,0,0,19,{"v":3.04109e-06,"d":"3.04E-06"},{"v":1.68524e-08,"d":"1.69E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","-","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs11250098;rs6601599;rs10903342;rs11250098:rs4240674:rs6601599",22]
["ENSG00000258724","SOX7",8,10582909,10697357,-1,"protein_coding",83595,"SOX7","NA",0.638029508,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs11250098:rs4240674:rs6601599;rs11250098",22]
["ENSG00000254093","PINX1",8,10622473,10697394,-1,"protein_coding",54984,"PINX1",{"v":4.9427916851122e-09,"d":"4.94E-09"},-0.063935492,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs11250098:rs4240674:rs6601599;rs11250098",22]
["ENSG00000171044","XKR6",8,10753555,11058875,-1,"protein_coding",286046,"XKR6",0.956776701241562,0.199430911,233,14.04,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.2e-35,"d":"1.20E-35"},"rs11250098;rs4240674;rs11250098:rs4240674:rs6601599;rs11250098:rs2976940:rs9772631:rs10099512:rs2126259:rs2126259;rs10099512:rs4240623:rs34290760:rs11774915:rs2126259;rs12546198:rs10102271:rs34365278:rs34365278;rs6601599","21:22:00"]
["ENSG00000215346","AF131215.5",8,10983980,10987745,-1,"protein_coding","NA","NA","NA","NA",14,4.532,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs11250098;rs11250098:rs6601599;rs11250098:rs4240674",22]
["ENSG00000104643","MTMR9",8,11141925,11185646,1,"protein_coding",66036,"MTMR9",0.210866148969841,1.579316819,3,2.582,73,{"v":4.52643e-07,"d":"4.53E-07"},{"v":4.11807E-6,"d":"4.12E-06"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Coronary","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.4e-09,"d":"7.40E-09"},"rs6601599;rs11250098;rs4240674;rs2467519;rs11250098:rs4240674:rs6601599;rs11250098:rs6601599:rs6601599;rs2467519:rs2467519:rs2010629",22]
["ENSG00000177710","SLC35G5",8,11188397,11189717,1,"protein_coding",83650,"SLC35G5",0.0274846347511103,0.517541682,0,0,124,{"v":8.45794e-07,"d":"8.46E-07"},{"v":1.15275e-05,"d":"1.15E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Pancreas","+","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs11250098;rs6601599;rs2467519;rs10903342;rs11250098:rs6601599;rs11250098:rs34365278:rs34365278;rs6601599:rs2010629:rs1692821;rs1293299:rs4841600:rs1692821:rs11786900;rs7846549:rs11779019:rs4240674:rs6601599:rs6601599;rs2467519:rs2467519:rs10903342:8:11336001_AT_A","21:22:00"]
["ENSG00000184608","C8orf12",8,11225911,11296167,1,"protein_coding",83656,"C8orf12",0.311268910075586,"NA",0,0,185,{"v":6.74532e-10,"d":"6.75E-10"},{"v":1.86718e-33,"d":"1.87E-33"},"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs11250098;rs34365278;rs6601599;rs2467519;rs10903342;rs1736070;rs1692821;rs1293299;rs11250098:rs6601599;rs11250098:rs34365278:rs34365278;rs6601599:rs10903342:rs6601599:rs6601599;rs2467519:rs2467519:rs2010629:rs1692821;rs1293299:rs4841600:rs1692821",22]
["ENSG00000154319","FAM167A",8,11278972,11332224,-1,"protein_coding",83648,"FAM167A",0.000192997889999534,0.911877562,26,10.02,10,{"v":3.43098e-05,"d":"3.43E-05"},0.0226044,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1e-11,"d":"1.00E-11"},"rs34365278;rs6601599;8:11336001_AT_A;rs11250098;rs6601599:rs6601599;rs11250098:rs34365278:rs34365278;rs2467519:rs2467519:rs1692821;rs1293299:rs4841600:rs1692821",22]
["ENSG00000136573","BLK",8,11351510,11422113,1,"protein_coding",640,"BLK",{"v":2.86165843035065e-07,"d":"2.86E-07"},-0.27366236,66,11.59,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1e-11,"d":"1.00E-11"},"rs6601599;8:11336001_AT_A;rs2467519;rs11250098;rs6601599:rs34365278:rs34365278;rs6601599:rs6601599;rs2467519:rs2467519:rs1692821;rs1293299:rs4841600:rs1692821:rs6601599",22]
["ENSG00000136574","GATA4",8,11534468,11617511,1,"protein_coding",2626,"GATA4",0.802155487205778,0.664928994,16,11,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs10903342;rs2010629;rs34365278:rs34365278;rs6601599:rs6601599;rs11250098:rs6601599:rs1692821;rs1293299:rs4841600:rs1692821:rs10903342",22]
["ENSG00000255394","C8orf49",8,11618896,11620309,1,"protein_coding",606553,"C8orf49","NA","NA",10,11,29,{"v":2.83733e-06,"d":"2.84E-06"},{"v":2.0822e-15,"d":"2.08E-15"},"GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs2010629;rs11250098;rs6601599;rs2467519;rs10903342;rs6601599:rs6601599;rs11250098:rs6601599;rs2467519:rs2467519:rs34365278:rs34365278;rs6601599:rs1692821;rs1293299:rs4841600:rs1692821",22]
["ENSG00000154328","NEIL2",8,11627148,11644855,1,"protein_coding",252969,"NEIL2",{"v":2.11099583099423e-09,"d":"2.11E-09"},2.689044542,11,11,261,{"v":7.82836e-11,"d":"7.83E-11"},{"v":1.67472E-21,"d":"1.67E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs2010629;rs1736070;rs6601599;rs11250098;rs2467519;rs4240674;rs34365278;rs10903342;rs1692821:rs6601599;rs11250098:rs6601599:rs6601599;rs2467519:rs2467519:rs34365278:rs34365278;rs6601599:rs1692821;rs1293299:rs4841600",22]
["ENSG00000079459","FDFT1",8,11653082,11696818,1,"protein_coding",2222,"FDFT1","NA",1.285658937,65,12.24,403,{"v":7.1869e-53,"d":"7.19E-53"},{"v":1.29552E-43,"d":"1.30E-43"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs2010629;rs1293299;rs1736070;rs4841600;rs1692821;rs11250098;rs6601599;rs34365278;rs2467519;rs10903342;rs4240674;8:11336001_AT_A;rs1692821:rs1692821;rs1293299:rs4841600:rs6601599:rs6601599;rs2467519:rs2467519:rs34365278:rs34365278",22]
["ENSG00000255046","RP11-297N6.4",8,11655437,11660077,-1,"protein_coding","NA","NA","NA","NA",22,11.09,86,{"v":4.22089e-09,"d":"4.22E-09"},{"v":5.37179e-09,"d":"5.37E-09"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs2010629;rs1293299;rs1736070;rs4841600;rs11250098;rs4240674;rs6601599;rs10903342;rs1692821:rs1692821;rs1293299:rs4841600:rs6601599:rs6601599;rs2467519:rs2467519:rs34365278:rs34365278",22]
["ENSG00000164733","CTSB",8,11700033,11726957,-1,"protein_coding",1508,"CTSB","NA",4.805364716,48,12.24,415,{"v":1.06701E-48,"d":"1.07E-48"},{"v":3.41996e-40,"d":"3.42E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs1692821;rs1293299;rs4841600;rs11250098;rs6601599;rs10903342;rs2010629;rs4240674;rs34365278;rs2467519;rs1736070;rs1293299:rs4841600:rs1692821:rs2010629:rs6601599;rs11250098:rs34365278:rs34365278;rs6601599:rs6601599:rs6601599;rs2467519:rs2467519:rs2010629;rs1293299:rs1736070:rs1293299:8:11336001_AT_A",22]
["ENSG00000205884","DEFB136",8,11831446,11832108,-1,"protein_coding",613210,"DEFB136",0.0340000990200746,0.27516663,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs6601599:rs2010629:rs11250098:rs6601599;rs11250098:rs34365278:rs34365278;rs6601599:rs6601599;rs2467519:rs2467519:rs1692821;rs1293299:rs4841600:rs1692821",22]
["ENSG00000205883","DEFB135",8,11839830,11842099,1,"protein_coding",613209,"DEFB135",{"v":1.31655071986469e-06,"d":"1.32E-06"},0.082643215,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-11,"d":"1.00E-11"},"rs6601599:rs2010629:rs1692821:rs6601599;rs2467519:rs2467519:rs11250098:rs6601599;rs11250098:rs34365278:rs34365278;rs6601599:rs1692821;rs1293299:rs4841600",22]
["ENSG00000205882","DEFB134",8,11850692,11853821,-1,"protein_coding",613211,"DEFB134",0.0322373411768572,0.812797609,0,0,218,{"v":1.67961e-12,"d":"1.68E-12"},{"v":1.26369e-17,"d":"1.26E-17"},"GTEx/v8/Pancreas","-","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.2E-10,"d":"4.20E-10"},"rs11250098;rs6601599;rs34365278;rs2467519;rs10903342;rs1736070;rs4841600;rs6601599:rs6601599;rs2467519:rs2467519:rs11250098:rs6601599;rs11250098:rs34365278:rs34365278",22]
["ENSG00000255098","RP11-481A20.11",8,11870545,11873043,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.9E-9,"d":"4.90E-09"},"rs6601599:rs6601599;rs2467519:rs2467519:rs11250098:rs6601599;rs11250098:rs34365278:rs34365278;rs6601599",22]
["ENSG00000186523","FAM86B1",8,12039605,12051642,-1,"protein_coding",85002,"FAM86B1",0.744460341331624,-0.801740789,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.2E-10,"d":"4.20E-10"},"rs10903342:rs1736070:rs4841600:rs1293299:rs2010629;rs1293299:rs1692821;rs1293299",22]
["ENSG00000232948","DEFB130",8,12168471,12175825,-1,"protein_coding",245940,"DEFB130","NA",0.318396342,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.3e-07,"d":"3.30E-07"},"rs6601599:8:11336001_AT_A",22]
["ENSG00000104763","ASAH1",8,17913934,17942494,-1,"protein_coding",427,"ASAH1",{"v":5.35814510968979e-11,"d":"5.36E-11"},2.324469628,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.9e-09,"d":"9.90E-09"},"rs4921915",23]
["ENSG00000171428","NAT1",8,18027986,18081198,1,"protein_coding",9,"NAT1",{"v":2.8541046904519e-10,"d":"2.85E-10"},1.834650928,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":9.9e-09,"d":"9.90E-09"},"rs4921915",23]
["ENSG00000156006","NAT2",8,18248755,18258728,1,"protein_coding",10,"NAT2",0.0226078662097717,0.267314509,19,11.29,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1e-06,"d":"1.00E-06"},"rs4921915",23]
["ENSG00000175445","LPL",8,19759228,19824769,1,"protein_coding",4023,"LPL",{"v":3.33727737763241e-06,"d":"3.34E-06"},1.047176611,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":9.9e-09,"d":"9.90E-09"},"rs4921915",23]
["ENSG00000181690","PLAG1",8,57073463,57123883,-1,"protein_coding",5324,"PLAG1",0.829917236319924,-1.103597026,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.2e-09,"d":"6.20E-09"},"rs2326077",24]
["ENSG00000170791","CHCHD7",8,57124245,57131357,1,"protein_coding",79145,"CHCHD7",0.387975837016134,-0.333440097,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.2e-09,"d":"6.20E-09"},"rs2326077",24]
["ENSG00000169122","FAM110B",8,58907068,59116838,1,"protein_coding",90362,"FAM110B",0.172625630799022,-0.286252494,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:GM12878:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":6.2e-09,"d":"6.20E-09"},"rs2326077",24]
["ENSG00000215114","UBXN2B",8,59323823,59364060,1,"protein_coding",137886,"UBXN2B",0.487567803186615,-0.274791059,17,15.8,27,{"v":2.12222e-07,"d":"2.12E-07"},{"v":7.71599e-24,"d":"7.72E-24"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Liver","+","Yes","Mesendoderm",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077;rs55704109",24]
["ENSG00000167910","CYP7A1",8,59402737,59412795,-1,"protein_coding",1581,"CYP7A1",0.00345536122276857,-0.121517501,10,20.8,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077;rs2326077:rs55704109:rs2326077;rs55704109",24]
["ENSG00000137575","SDCBP",8,59465483,59495419,1,"protein_coding",6386,"SDCBP",0.000811571828670198,-0.857907679,0,0,30,{"v":1.23518E-12,"d":"1.24E-12"},{"v":1.92649e-11,"d":"1.93E-11"},"GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","No","NA",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077;rs55704109",24]
["ENSG00000035681","NSMAF",8,59496063,59572403,-1,"protein_coding",8439,"NSMAF",{"v":3.1837468420093e-08,"d":"3.18E-08"},"NA",0,0,28,{"v":2.50444e-06,"d":"2.50E-06"},0.000175602,"GTEx/v8/Artery_Aorta","-","No","NA",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077;rs55704109",24]
["ENSG00000178538","CA8",8,61099906,61193971,-1,"protein_coding",767,"CA8",0.783927466808709,0.803920845,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077:rs2326077;rs55704109:rs55704109",24]
["ENSG00000104388","RAB2A",8,61429416,61536186,1,"protein_coding",5862,"RAB2A",0.970735512688083,-0.412665448,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077:rs2326077;rs55704109",24]
["ENSG00000171316","CHD7",8,61591337,61779465,1,"protein_coding",55636,"CHD7",0.999999999999751,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.2e-11,"d":"1.20E-11"},"rs2326077;rs55704109:rs2326077",24]
["ENSG00000104447","TRPS1",8,116420724,116821899,-1,"protein_coding",7227,"TRPS1",0.990109017620343,-0.347407506,187,21.3,1,{"v":6.87775e-05,"d":"6.88E-05"},{"v":3.0131E-6,"d":"3.01E-06"},"GTEx/v8/Pancreas","+","No","NA",{"v":6E-10,"d":"6.00E-10"},"rs4876611;rs4876612",25]
["ENSG00000147677","EIF3H",8,117654369,117779164,-1,"protein_coding",8667,"EIF3H",0.465051249825806,1.14862982,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6E-10,"d":"6.00E-10"},"rs4876612:rs4876611",25]
["ENSG00000147679","UTP23",8,117778742,117861702,1,"protein_coding",84294,"UTP23",0.033108947324346,-0.373647173,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6E-10,"d":"6.00E-10"},"rs4876612:rs4876611",25]
["ENSG00000164754","RAD21",8,117858174,117887105,-1,"protein_coding",5885,"RAD21",0.999544949425601,-0.354117972,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesendoderm",{"v":6E-10,"d":"6.00E-10"},"rs4876611",25]
["ENSG00000205002","AARD",8,117950438,117956726,1,"protein_coding",441376,"AARD",0.328326488367201,-0.355449514,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6E-10,"d":"6.00E-10"},"rs4876611:rs4876612",25]
["ENSG00000164756","SLC30A8",8,117962512,118188953,1,"protein_coding",169026,"SLC30A8",{"v":1.79754250091306e-09,"d":"1.80E-09"},0.25841764,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesendoderm:hESC",{"v":6E-10,"d":"6.00E-10"},"rs4876612:rs4876611",25]
["ENSG00000177570","SAMD12",8,119201698,119634234,-1,"protein_coding",401474,"SAMD12",1.31724341047217E-3,-0.015787042,0,0,0,"NA","NA","NA","NA","Yes","hESC",{"v":6E-10,"d":"6.00E-10"},"rs4876611",25]
["ENSG00000189376","C8orf76",8,124232196,124253638,-1,"protein_coding",84933,"C8orf76",{"v":1.71944218858493e-05,"d":"1.72E-05"},-0.020072916,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.6E-13,"d":"1.60E-13"},"rs4360309",26]
["ENSG00000259305","ZHX1-C8ORF76",8,124238431,124279627,-1,"protein_coding",100533106,"ZHX1-C8ORF76",0.00105203127523669,-0.36802306,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.6E-13,"d":"1.60E-13"},"rs4360309",26]
["ENSG00000170881","RNF139",8,125486979,125500155,1,"protein_coding",11236,"RNF139",0.0608738334958745,-0.469220523,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.6E-13,"d":"1.60E-13"},"rs4360309",26]
["ENSG00000147687","TATDN1",8,125500726,125551699,-1,"protein_coding",83940,"TATDN1",{"v":1.72640600686597e-08,"d":"1.73E-08"},0.357863168,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-52,"d":"3.20E-52"},"rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309",26]
["ENSG00000147684","NDUFB9",8,125551344,125580751,1,"protein_coding",4715,"NDUFB9",0.0428894468164687,-0.016587227,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-52,"d":"3.20E-52"},"rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309",26]
["ENSG00000180938","ZNF572",8,125985540,125991631,1,"protein_coding",137209,"ZNF572",0.000651450621070101,-0.137914163,0,0,0,"NA","NA","NA","NA","Yes","Liver",{"v":3.2e-52,"d":"3.20E-52"},"rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G",26]
["ENSG00000104549","SQLE",8,126010739,126034525,1,"protein_coding",6713,"SQLE",0.91297067975512,1.171693492,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-52,"d":"3.20E-52"},"rs4360309:rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G",26]
["ENSG00000164961","KIAA0196",8,126036502,126104082,-1,"protein_coding",9897,"KIAA0196",{"v":4.81024990398197e-13,"d":"4.81E-13"},-0.762157486,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-52,"d":"3.20E-52"},"rs2385114:rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309:rs2980874",26]
["ENSG00000156831","NSMCE2",8,126103921,126379362,1,"protein_coding",286053,"NSMCE2",0.0724507212755206,-0.471934498,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:Pancreas:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.2e-52,"d":"3.20E-52"},"rs2385114:rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G:rs4360309:rs2980874",26]
["ENSG00000173334","TRIB1",8,126442563,126450647,1,"protein_coding",10221,"TRIB1",0.606587656595858,-0.456914247,16,14.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":3.8e-16,"d":"3.80E-16"},"rs2980874;rs2385114;rs4871598;rs12674939;rs4360309:rs2385114",26]
["ENSG00000136997","MYC",8,128747680,128753674,1,"protein_coding",4609,"MYC","NA",-0.253124713,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3.2e-52,"d":"3.20E-52"},"rs112875651;rs2954021:rs33924196;rs2980884:rs33924196;8:126492843_GT_G:rs35309034;rs12674939:rs2954021:rs72655677:rs33924196:rs58253018:rs33924196;8:126492843_GT_G;rs2980884:8:126492843_GT_G:rs35309034:8:126504383_CCACCAT_C:rs112875651:8:126511216_GA_G",26]
["ENSG00000167632","TRAPPC9",8,140742586,141468678,-1,"protein_coding",83696,"TRAPPC9",{"v":5.76038953455576e-06,"d":"5.76E-06"},-0.335502478,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.5e-08,"d":"3.50E-08"},"rs7831074",27]
["ENSG00000104472","CHRAC1",8,141521397,141527236,1,"protein_coding",54108,"CHRAC1",0.658094860543726,0.283658574,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":3.5e-08,"d":"3.50E-08"},"rs7831074",27]
["ENSG00000123908","AGO2",8,141541264,141645718,-1,"protein_coding",27161,"AGO2",0.999992248962312,-0.029821522,1,1.126,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.5e-08,"d":"3.50E-08"},"rs7831074",27]
["ENSG00000105339","DENND3",8,142127377,142205907,1,"protein_coding",22898,"DENND3",0.0171730327867355,0.99937938,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":3.5e-08,"d":"3.50E-08"},"rs7831074",27]
["ENSG00000153714","LURAP1L",9,12775020,12822130,1,"protein_coding",286343,"LURAP1L",0.0766242694095508,0.220603476,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000107186","MPDZ",9,13105703,13279589,-1,"protein_coding",8777,"MPDZ","NA",0.345884525,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000175893","ZDHHC21",9,14611069,14693469,-1,"protein_coding",340481,"ZDHHC21",0.0512303788505532,1.009801353,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000147869","CER1",9,14719722,14722715,-1,"protein_coding",9350,"CER1",{"v":2.57822812120588e-05,"d":"2.58E-05"},-0.00799085,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000164946","FREM1",9,14734664,14910993,-1,"protein_coding",158326,"FREM1","NA",2.024228525,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:hESC",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000155158","TTC39B",9,15163620,15307358,-1,"protein_coding",158219,"TTC39B",{"v":1.06813738722138E-11,"d":"1.07E-11"},0.056260627,25,16.34,22,{"v":1.18588E-8,"d":"1.19E-08"},{"v":1.2245e-09,"d":"1.22E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049;rs4008004",28]
["ENSG00000164975","SNAPC3",9,15422702,15465951,1,"protein_coding",6619,"SNAPC3",{"v":5.53901197607186e-05,"d":"5.54E-05"},1.456738075,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000164985","PSIP1",9,15464064,15511017,-1,"protein_coding",11168,"PSIP1",0.946350057562085,0.382466325,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000164989","CCDC171",9,15552895,16061661,1,"protein_coding",203238,"CCDC171","NA",0.216049891,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.4E-11,"d":"1.40E-11"},"rs2849049:rs4008004",28]
["ENSG00000155833","CYLC2",9,105757593,105780770,1,"protein_coding",1539,"CYLC2",{"v":5.14081582239004e-07,"d":"5.14E-07"},1.40861542,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":4.5e-12,"d":"4.50E-12"},"rs2245793:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461:rs62568184;rs774976461:rs4149273",29]
["ENSG00000136783","NIPSNAP3A",9,107509969,107522403,1,"protein_coding",25934,"NIPSNAP3A",{"v":1.63591359584979e-05,"d":"1.64E-05"},0.213980976,0,0,13,{"v":9.99937e-08,"d":"1.00E-07"},{"v":2.58137e-25,"d":"2.58E-25"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage","-","No","NA",{"v":4.3e-09,"d":"4.30E-09"},"rs3824477;rs2245793",29]
["ENSG00000165028","NIPSNAP3B",9,107526438,107539738,1,"protein_coding",55335,"NIPSNAP3B",0.0238829678663823,-0.281408699,2,9.246,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-12,"d":"1.80E-12"},"rs2245793;rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461:rs62568184;rs774976461:rs4149273",29]
["ENSG00000165029","ABCA1",9,107543283,107690518,-1,"protein_coding",19,"ABCA1",0.00165880319635912,0.082774215,130,16.72,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.8e-28,"d":"6.80E-28"},"rs2245793;rs3824477;rs4149307;rs36050540;9:107603722_AAAAAAG_A;rs12004282;rs11791258;rs774976461;rs62568184;rs4149273;rs2740488;rs73664373;rs1800978;rs2254819;rs3905001;rs2437818;rs4149273:rs1800978:rs73664373:rs2740488:rs4149273:rs2254819:rs3905001:rs62568184:rs62568184;rs774976461:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461",29]
["ENSG00000070214","SLC44A1",9,108006903,108201452,1,"protein_coding",23446,"SLC44A1",0.999253571367297,-0.569151,0,0,9,{"v":1.76327e-06,"d":"1.76E-06"},0.00432065,"GTEx/v8/Adipose_Visceral_Omentum","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.8e-28,"d":"6.80E-28"},"rs774976461;rs62568184;rs12004282:rs11791258;rs12004282;rs774976461:rs2740488;rs4149273:rs1800978:rs73664373:rs2740488:rs4149273:rs2254819:rs3905001:rs62568184:rs62568184;rs774976461:rs36050540:9:107603722_AAAAAAG_A:rs11791258;rs12004282:rs11791258:rs774976461:rs2245793:rs3824477:rs4149307:rs2437818",29]
["ENSG00000106701","FSD1L",9,108210077,108314714,1,"protein_coding",83856,"FSD1L","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.8e-28,"d":"6.80E-28"},"rs12004282:rs11791258;rs12004282;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461:rs62568184;rs774976461:rs4149273:rs2740488;rs4149273:rs1800978:rs73664373:rs2740488:rs2254819:rs3905001:rs62568184:rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs2437818",29]
["ENSG00000106692","FKTN",9,108320411,108403399,1,"protein_coding",2218,"FKTN",0.000192375264435551,-1.003484248,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.8E-12,"d":"1.80E-12"},"rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461:rs62568184;rs774976461:rs4149273",29]
["ENSG00000186051","TAL2",9,108424738,108425367,1,"protein_coding",6887,"TAL2",0.488535069507167,0.093363904,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.8e-28,"d":"6.80E-28"},"rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461:rs62568184;rs774976461:rs4149273:rs2740488;rs4149273:rs73664373:rs62568184:rs1800978:rs2740488:rs2254819:rs3905001:rs2437818",29]
["ENSG00000095209","TMEM38B",9,108456825,108538893,1,"protein_coding",55151,"TMEM38B",0.1687999661801,0.890196099,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-12,"d":"1.80E-12"},"rs2245793:rs3824477:rs4149307:rs36050540:9:107603722_AAAAAAG_A:rs12004282:rs11791258;rs12004282;rs774976461:rs11791258;rs12004282:rs11791258:rs774976461:rs62568184;rs774976461:rs4149273",29]
["ENSG00000125485","DDX31",9,135468384,135545788,-1,"protein_coding",64794,"DDX31",{"v":2.75575676923568e-06,"d":"2.76E-06"},-0.899017337,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.3e-16,"d":"5.30E-16"},"rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",30]
["ENSG00000125484","GTF3C4",9,135545422,135570342,1,"protein_coding",9329,"GTF3C4",0.0149762555569875,0.796705006,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.3e-16,"d":"5.30E-16"},"rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",30]
["ENSG00000148308","GTF3C5",9,135906076,135933890,1,"protein_coding",9328,"GTF3C5",0.00274002234197739,-0.524089361,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":6.1e-08,"d":"6.10E-08"},"rs56343119;rs28538967:rs56343119",30]
["ENSG00000160271","RALGDS",9,135973107,136039301,-1,"protein_coding",5900,"RALGDS",0.296706347503849,-0.211408361,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.4e-08,"d":"4.40E-08"},"rs11244084",30]
["ENSG00000148288","GBGT1",9,136028340,136039332,-1,"protein_coding",26301,"GBGT1",1.00077199027406E-4,0.668450581,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.4e-08,"d":"4.40E-08"},"rs11244084",30]
["ENSG00000171102","OBP2B",9,136080664,136084630,-1,"protein_coding",29989,"OBP2B",0.182972936041483,-0.121398936,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":5.3e-16,"d":"5.30E-16"},"rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",30]
["ENSG00000148296","SURF6",9,136197552,136203235,-1,"protein_coding",6838,"SURF6",{"v":8.12446562293265e-05,"d":"8.12E-05"},-0.437227567,1,1.451,1,{"v":8.97688E-5,"d":"8.98E-05"},{"v":6.44478E-55,"d":"6.44E-55"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.7e-09,"d":"5.70E-09"},"rs11244084;rs11244061;rs56343119:rs28538967",30]
["ENSG00000148297","MED22",9,136205160,136214986,-1,"protein_coding",6837,"MED22",0.00632213991393259,-0.130266294,3,8.347,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.8e-09,"d":"3.80E-09"},"rs56343119;rs28538967;rs28538967:rs56343119",30]
["ENSG00000148303","RPL7A",9,136215069,136218281,1,"protein_coding",6130,"RPL7A",0.979405408797334,"NA",3,8.347,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.8e-09,"d":"3.80E-09"},"rs56343119;rs28538967;rs28538967:rs56343119",30]
["ENSG00000148290","SURF1",9,136218610,136223552,-1,"protein_coding",6834,"SURF1",{"v":1.02063910629184E-13,"d":"1.02E-13"},"NA",3,8.347,37,{"v":9.03612e-27,"d":"9.04E-27"},{"v":2.67588e-56,"d":"2.68E-56"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-16,"d":"5.30E-16"},"rs56343119;rs28538967;rs115478735;rs550057;rs11244061;rs11244084;rs56343119:rs28538967",30]
["ENSG00000148291","SURF2",9,136223428,136228045,1,"protein_coding",6835,"SURF2",{"v":3.07087198881956e-07,"d":"3.07E-07"},"NA",4,8.347,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967;rs56343119:rs28538967",30]
["ENSG00000148248","SURF4",9,136228325,136242970,-1,"protein_coding",6836,"SURF4",0.686424182931678,-0.490474887,3,3.697,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967;rs56343119:rs11244084",30]
["ENSG00000198870","C9orf96",9,136243117,136271220,1,"protein_coding",169436,"C9orf96",{"v":2.54706971388686e-16,"d":"2.55E-16"},"NA",7,12.15,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967;rs56343119:rs11244084",30]
["ENSG00000148300","REXO4",9,136271186,136283164,-1,"protein_coding",57109,"REXO4",{"v":9.99455362636825e-06,"d":"9.99E-06"},1.530845821,4,12.15,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.8E-9,"d":"1.80E-09"},"rs56343119;rs28538967;rs28538967:rs56343119:rs11244084:rs28538967",30]
["ENSG00000160323","ADAMTS13",9,136279478,136324508,1,"protein_coding",11093,"ADAMTS13",{"v":7.88296728194754e-11,"d":"7.88E-11"},-0.276084391,11,16.74,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.8e-09,"d":"3.80E-09"},"rs56343119;rs28538967;rs28538967:rs28538967:rs56343119",30]
["ENSG00000160325","CACFD1",9,136325089,136335970,1,"protein_coding",11094,"CACFD1",0.00574676872876184,"NA",8,16.74,4,{"v":1.14306E-5,"d":"1.14E-05"},{"v":1.39999e-07,"d":"1.40E-07"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-16,"d":"5.30E-16"},"rs28538967;rs56343119;rs28538967:rs56343119;rs28538967:rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",30]
["ENSG00000160326","SLC2A6",9,136336217,136344259,-1,"protein_coding",11182,"SLC2A6",0.000366664150450035,-0.033260488,5,16.74,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-16,"d":"5.30E-16"},"rs56343119;rs28538967:rs28538967:rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",30]
["ENSG00000187616","TMEM8C",9,136379708,136393734,-1,"protein_coding",389827,"TMEM8C",2.16915928417017E-3,0.106132843,0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-16,"d":"5.30E-16"},"rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061:rs56343119;rs28538967:rs28538967",30]
["ENSG00000197859","ADAMTSL2",9,136397286,136440641,1,"protein_coding",9719,"ADAMTSL2",0.0710586670580913,"NA",0,0,0,"NA","NA","NA","NA","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.3e-16,"d":"5.30E-16"},"rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061:rs56343119;rs28538967:rs28538967",30]
["ENSG00000196990","FAM163B",9,136444079,136451319,-1,"protein_coding",642968,"FAM163B",0.428150995206124,-0.470114741,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.3e-16,"d":"5.30E-16"},"rs56343119:rs9411377:rs550057;rs9411377:rs115478735:rs550057:rs11244061",30]
["ENSG00000123453","SARDH",9,136528682,136605077,-1,"protein_coding",1757,"SARDH",{"v":8.19688048123126e-10,"d":"8.20E-10"},-0.160035756,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7.1e-07,"d":"7.10E-07"},"rs56343119",30]
["ENSG00000169925","BRD3",9,136895427,136933657,-1,"protein_coding",8019,"BRD3",0.766979379296961,1.798261326,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.1e-08,"d":"6.10E-08"},"rs56343119;rs28538967",30]
["ENSG00000067057","PFKP",10,3108525,3179904,1,"protein_coding",5214,"PFKP",{"v":7.08342752970718E-15,"d":"7.08E-15"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.7e-07,"d":"1.70E-07"},"rs117488242",31]
["ENSG00000165568","AKR1E2",10,4828821,4890254,1,"protein_coding",83592,"AKR1E2",{"v":6.35197354907988e-06,"d":"6.35E-06"},1.491626915,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs117488242",31]
["ENSG00000187134","AKR1C1",10,4934796,5025475,1,"protein_coding",1645,"AKR1C1",{"v":8.39898077933769e-06,"d":"8.40E-06"},5.07378856,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs117488242",31]
["ENSG00000151632","AKR1C2",10,5029967,5060223,-1,"protein_coding",1646,"AKR1C2",4.10317193583082E-3,2.217081159,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs117488242",31]
["ENSG00000196139","AKR1C3",10,5077546,5149878,1,"protein_coding",8644,"AKR1C3",{"v":1.07139398635711e-11,"d":"1.07E-11"},0.642111095,33,6.566,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs117488242",31]
["ENSG00000196326","AKR1CL1",10,5196335,5244449,-1,"protein_coding",340811,"AKR1CL1","NA","NA",64,13.31,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.2e-08,"d":"2.20E-08"},"rs117488242",31]
["ENSG00000198610","AKR1C4",10,5237425,5260912,1,"protein_coding",1109,"AKR1C4",{"v":1.68467759451019e-10,"d":"1.68E-10"},0.954241307,109,13.31,0,"NA","NA","NA","NA","No","NA",{"v":1.8e-08,"d":"1.80E-08"},"rs117488242",31]
["ENSG00000178473","UCN3",10,5406972,5416169,1,"protein_coding",114131,"UCN3",0.508143909845209,-0.445788037,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs117488242",31]
["ENSG00000178462","TUBAL3",10,5435061,5446793,-1,"protein_coding",79861,"TUBAL3",1.70843012375288E-4,0.87987711,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs117488242",31]
["ENSG00000173848","NET1",10,5454514,5500426,1,"protein_coding",10276,"NET1",0.0668541946676421,-0.115573761,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-08,"d":"1.80E-08"},"rs117488242",31]
["ENSG00000108021","FAM208B",10,5726801,5805703,1,"protein_coding",54906,"FAM208B",0.96506326510446,-0.778203824,0,0,0,"NA","NA","NA","NA","Yes","IMR90:hESC",{"v":1.7e-07,"d":"1.70E-07"},"rs117488242",31]
["ENSG00000198879","SFMBT2",10,7200586,7453450,-1,"protein_coding",57713,"SFMBT2",0.996407769866383,-0.14836908,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.7e-07,"d":"1.70E-07"},"rs117488242",31]
["ENSG00000196793","ZNF239",10,44051792,44070066,-1,"protein_coding",8187,"ZNF239",0.000867929253552217,0.570932296,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":6.1e-10,"d":"6.10E-10"},"rs148063610;rs10793624:rs148063610;rs150231142:rs148063610;rs150231142;rs10793624",32]
["ENSG00000169740","ZNF32",10,44139307,44144304,-1,"protein_coding",7580,"ZNF32",0.276205822566686,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":4.5E-10,"d":"4.50E-10"},"rs148063610;rs10793624:rs148063610;rs150231142:rs148063610;rs150231142",32]
["ENSG00000187783","TMEM72",10,45406648,45432450,1,"protein_coding",643236,"TMEM72",0.49453096966628,1.768118555,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.3e-09,"d":"1.30E-09"},"rs148063610;rs150231142;rs10793624",32]
["ENSG00000165507","C10orf10",10,45466429,45474258,-1,"protein_coding",11067,"C10orf10",{"v":3.86908584231525e-05,"d":"3.87E-05"},0.524652874,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.7e-10,"d":"4.70E-10"},"rs148063610;rs150231142:rs148063610;rs150231142;rs10793624:rs148063610;rs10793624",32]
["ENSG00000165511","C10orf25",10,45493146,45496336,-1,"protein_coding",220979,"C10orf25",0.012567313038728,-0.929200156,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:hESC",{"v":4.5E-10,"d":"4.50E-10"},"rs148063610;rs150231142;rs10793624:rs148063610;rs10793624:rs148063610:rs148063610",32]
["ENSG00000165512","ZNF22",10,45495923,45500774,1,"protein_coding",7570,"ZNF22",0.126684327200881,-0.107262233,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:hESC",{"v":4.5E-10,"d":"4.50E-10"},"rs148063610;rs150231142;rs10793624:rs148063610;rs10793624:rs148063610:rs148063610",32]
["ENSG00000256574","OR13A1",10,45798102,45811056,-1,"protein_coding",79290,"OR13A1",2.12216731545614E-4,0.297808605,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.3e-09,"d":"5.30E-09"},"rs148063610;rs150231142;rs10793624",32]
["ENSG00000012779","ALOX5",10,45869661,45941561,1,"protein_coding",240,"ALOX5",1.64439332581691E-3,"NA",0,0,10,{"v":8.9692e-05,"d":"8.97E-05"},{"v":5.70457e-10,"d":"5.70E-10"},"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Left_Ventricle",{"v":4.5E-10,"d":"4.50E-10"},"rs148063610;rs150231142;rs150231142:rs148063610;rs10793624:rs148063610",32]
["ENSG00000165406","2008-03-01",10,45950035,46090354,-1,"protein_coding",220972,"2008-03-01",{"v":1.37263384630584e-05,"d":"1.37E-05"},-0.165648458,58,15.6,41,{"v":6.27958e-08,"d":"6.28E-08"},{"v":2.41813e-15,"d":"2.42E-15"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops",{"v":6.8e-11,"d":"6.80E-11"},"rs148063610;rs150231142;rs10793624",32]
["ENSG00000172671","ZFAND4",10,46111043,46168228,-1,"protein_coding",93550,"ZFAND4",0.00925156548332018,0.078714079,6,6.821,22,{"v":4.87453e-09,"d":"4.87E-09"},{"v":9.0563e-26,"d":"9.06E-26"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops",{"v":3.9E-10,"d":"3.90E-10"},"rs148063610;rs150231142;rs10793624;rs150231142:rs148063610;rs10793624:rs148063610;rs10793624:rs10793624",32]
["ENSG00000172661","FAM21C",10,46222648,46288409,1,"protein_coding",253725,"FAM21C","NA",0.129559906,5,6.848,64,{"v":1.30119E-32,"d":"1.30E-32"},{"v":1.88308e-34,"d":"1.88E-34"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","No","NA",{"v":3.6E-10,"d":"3.60E-10"},"rs148063610;rs150231142;rs10793624",32]
["ENSG00000188234","AGAP4",10,46321042,46349323,-1,"protein_coding",119016,"AGAP4","NA","NA",0,0,5,{"v":9.24652e-05,"d":"9.25E-05"},{"v":2.53526e-107,"d":"2.54E-107"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":5e-10,"d":"5.00E-10"},"rs148063610;rs150231142",32]
["ENSG00000204174","NPY4R",10,47083534,47088320,1,"protein_coding",5540,"NPY4R",{"v":6.11597013241374e-09,"d":"6.12E-09"},0.487893073,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":6.8e-11,"d":"6.80E-11"},"rs148063610;rs10793624:rs148063610;rs150231142:rs148063610:rs148063610;rs150231142;rs10793624",32]
["ENSG00000175216","CKAP5",11,46764598,46867847,-1,"protein_coding",9793,"CKAP5",0.99999999753418,-0.360017002,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.6e-09,"d":"1.60E-09"},"11:47650138_AT_A:rs3972616",33]
["ENSG00000134569","LRP4",11,46878419,46940193,-1,"protein_coding",4038,"LRP4",0.10020880429216,0.314361929,0,0,4,{"v":6.68079e-07,"d":"6.68E-07"},{"v":4.55827e-32,"d":"4.56E-32"},"GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops",{"v":4.4e-09,"d":"4.40E-09"},"11:47650138_AT_A;rs12790666",33]
["ENSG00000149179","C11orf49",11,46958240,47185936,1,"protein_coding",79096,"C11orf49",{"v":5.45467879227827e-07,"d":"5.45E-07"},0.564557873,0,0,1,0.000568611,0.000636697,"GTEx/v8/Artery_Tibial","+","No","NA",{"v":2.1E-10,"d":"2.10E-10"},"11:47650138_AT_A",33]
["ENSG00000149182","ARFGAP2",11,47185848,47198676,-1,"protein_coding",84364,"ARFGAP2",0.562990971385505,-0.150781591,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A",33]
["ENSG00000165912","PACSIN3",11,47199076,47207994,-1,"protein_coding",29763,"PACSIN3",0.0167930476176259,-0.514938878,0,0,9,{"v":5.92561e-05,"d":"5.93E-05"},{"v":2.82949E-14,"d":"2.83E-14"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops",{"v":1.8E-10,"d":"1.80E-10"},"rs4752891;rs7124275;11:47650138_AT_A",33]
["ENSG00000134574","DDB2",11,47236493,47260767,1,"protein_coding",1643,"DDB2",0.00511790717237921,0.677015289,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.5e-10,"d":"2.50E-10"},"11:47650138_AT_A",33]
["ENSG00000134575","ACP2",11,47260853,47270457,-1,"protein_coding",53,"ACP2",0.00052597665714545,-0.370782179,0,0,181,{"v":7.55603e-08,"d":"7.56E-08"},{"v":5.15985e-08,"d":"5.16E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs3972616;rs12790666;rs6485802;11:47650138_AT_A:rs12790666:rs3972616",33]
["ENSG00000025434","NR1H3",11,47269851,47290396,1,"protein_coding",10062,"NR1H3",0.856185983167695,0.657584133,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A:rs12790666:rs3972616",33]
["ENSG00000110514","MADD",11,47290712,47351582,1,"protein_coding",8567,"MADD",0.000901823421065546,-0.375050357,0,0,172,{"v":1.40214e-07,"d":"1.40E-07"},{"v":2.07197E-8,"d":"2.07E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":4.3E-11,"d":"4.30E-11"},"rs3972616;11:47650138_AT_A;11:47650138_AT_A:rs3972616",33]
["ENSG00000134571","MYBPC3",11,47352957,47374253,-1,"protein_coding",4607,"MYBPC3",{"v":1.35053975034244E-6,"d":"1.35E-06"},-0.432352402,27,14.21,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:IMR90:Mesenchymal_Stem_Cell",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A;rs3972616",33]
["ENSG00000066336","SPI1",11,47376411,47400127,-1,"protein_coding",6688,"SPI1",0.89723051716191,"NA",52,14.21,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:EP_correlation_organ_oneway:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs3972616;11:47650138_AT_A:rs12790666:rs3972616",33]
["ENSG00000165915","SLC39A13",11,47428683,47438047,1,"protein_coding",91252,"SLC39A13",0.0118520311660311,-0.332418514,35,21.7,190,{"v":4.13876E-17,"d":"4.14E-17"},{"v":1.13327e-12,"d":"1.13E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs12790666;rs3972616;rs374209699;rs7124275;rs56692100;rs6485802;11:47650138_AT_A:rs3972616:rs4752891",33]
["ENSG00000165916","PSMC3",11,47440320,47447993,-1,"protein_coding",5702,"PSMC3",0.979199713289554,-0.404697103,27,14.02,280,{"v":1.87235e-14,"d":"1.87E-14"},{"v":2.36421e-11,"d":"2.36E-11"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs12790666;rs6485802;rs3972616;rs4752891;rs7124275;rs374209699;rs56692100",33]
["ENSG00000165917","RAPSN",11,47459308,47470730,-1,"protein_coding",5913,"RAPSN",0.0326445463388561,0.048781604,10,10.14,185,{"v":2.66002e-08,"d":"2.66E-08"},{"v":6.17155e-05,"d":"6.17E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs3972616;rs12790666;rs6485802;rs4752891",33]
["ENSG00000149187","CELF1",11,47487496,47587121,-1,"protein_coding",10658,"CELF1",0.998616884875254,-0.376215763,17,17.63,8,0.000370412,4.61108E-4,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.9e-11,"d":"5.90E-11"},"11:47650138_AT_A;11:47650138_AT_A:rs374209699;rs7124275;rs56692100:rs7124275;rs4752891:rs12790666:rs3972616",33]
["ENSG00000213619","NDUFS3",11,47586888,47606114,1,"protein_coding",4722,"NDUFS3",0.0471370341289045,-0.012344566,8,14.52,1,{"v":9.79137e-05,"d":"9.79E-05"},0.0271439,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.9e-11,"d":"5.90E-11"},"11:47650138_AT_A;11:47650138_AT_A:rs374209699;rs7124275;rs56692100:rs7124275;rs4752891:rs12790666:rs3972616",33]
["ENSG00000110536","PTPMT1",11,47586982,47595013,1,"protein_coding",114971,"PTPMT1",0.459152455272006,"NA",5,11.24,185,{"v":7.83196e-06,"d":"7.83E-06"},0.000699996,"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.9e-11,"d":"5.90E-11"},"11:47650138_AT_A;rs6485802;rs12790666;rs4752891;rs7124275;rs56692100;rs374209699;11:47650138_AT_A:rs374209699;rs56692100:rs7124275;rs4752891:rs12790666:rs3972616",33]
["ENSG00000123444","KBTBD4",11,47593749,47600567,-1,"protein_coding",55709,"KBTBD4",0.0180743639557145,-0.492620783,5,9.104,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A;11:47650138_AT_A:rs3972616:rs4752891:rs12790666",33]
["ENSG00000231880","KBTBD4",11,47599277,47599823,1,"protein_coding",55709,"KBTBD4","NA",-0.492620783,4,9.104,0,"NA","NA","NA","NA","Yes","EP_links_oneway:Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":5.9e-11,"d":"5.90E-11"},"11:47650138_AT_A;11:47650138_AT_A:rs3972616:rs4752891:rs12790666",33]
["ENSG00000196666","FAM180B",11,47608198,47610746,1,"protein_coding",399888,"FAM180B",0.315838165150116,"NA",5,14.52,230,{"v":4.5199e-05,"d":"4.52E-05"},0.0158999,"GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A;rs7124275;rs56692100;rs374209699;11:47650138_AT_A:rs3972616:rs4752891:rs12790666",33]
["ENSG00000172247","C1QTNF4",11,47611216,47616211,-1,"protein_coding",114900,"C1QTNF4",0.679081390678169,"NA",9,14.52,577,{"v":4.30565e-65,"d":"4.31E-65"},{"v":1.21395E-52,"d":"1.21E-52"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs3972616;rs12790666;rs4752891;rs7124275;rs56692100;rs374209699;rs6485802;11:47650138_AT_A:rs3972616:rs12790666",33]
["ENSG00000109919","MTCH2",11,47638867,47664175,-1,"protein_coding",23788,"MTCH2",0.166788403447163,0.036933631,17,25,169,{"v":7.83136e-06,"d":"7.83E-06"},0.0042687,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs12790666;rs6485802:11:47650138_AT_A:rs3972616:rs4752891",33]
["ENSG00000165923","AGBL2",11,47681143,47736941,-1,"protein_coding",79841,"AGBL2",{"v":6.81051045839789e-12,"d":"6.81E-12"},-0.765874431,13,7.718,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.3E-11,"d":"4.30E-11"},"11:47650138_AT_A;rs3972616;11:47650138_AT_A:rs3972616:rs4752891:rs6485802:rs7124275;rs4752891",33]
["ENSG00000109920","FNBP4",11,47738072,47788995,-1,"protein_coding",23360,"FNBP4",0.999993422916695,-0.713792045,19,7.718,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A;rs6485802:11:47650138_AT_A:rs4752891:rs7124275;rs4752891",33]
["ENSG00000030066","NUP160",11,47799639,47870107,-1,"protein_coding",23279,"NUP160",0.023979152527532,-0.34569366,26,11.78,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.9e-11,"d":"7.90E-11"},"11:47650138_AT_A;rs6485802;11:47650138_AT_A:rs6485802:rs3972616:rs4752891:rs7124275;rs4752891:rs7124275",33]
["ENSG00000149177","PTPRJ",11,48002113,48189670,1,"protein_coding",5795,"PTPRJ",{"v":2.38654353395849E-5,"d":"2.39E-05"},"NA",50,15.35,1064,{"v":8.08469e-19,"d":"8.08E-19"},{"v":1.09337E-14,"d":"1.09E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.3E-11,"d":"4.30E-11"},"rs6485802;rs4752891;rs7124275;rs12790666;rs56692100;rs374209699;11:47650138_AT_A;rs3972616;rs6485802:rs4752891:11:47650138_AT_A:rs7124275;rs4752891:rs12790666",33]
["ENSG00000175619","OR4B1",11,48238344,48239314,1,"protein_coding",119765,"OR4B1",0.0109380186584993,0.304380954,6,8.853,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs7124275;rs4752891;rs56692100;rs374209699;rs56692100:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",33]
["ENSG00000172208","OR4X2",11,48266608,48267622,1,"protein_coding",119764,"OR4X2",{"v":1.10988723254503e-08,"d":"1.11E-08"},0.281681038,3,7.562,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs7124275;rs4752891;rs374209699;rs56692100:rs7124275:rs4752891:rs374209699;rs7124275:rs374209699:rs7124275;rs56692100:rs56692100:rs7124275",33]
["ENSG00000176567","OR4X1",11,48285413,48286330,1,"protein_coding",390113,"OR4X1",0.00015767458987061,0.540389506,5,23.5,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs7124275;rs4752891;rs374209699;rs56692100:rs7124275;rs4752891:rs7124275:rs7124275;rs56692100:rs4752891:rs56692100:rs374209699;rs7124275:rs374209699",33]
["ENSG00000176555","OR4S1",11,48327775,48328704,1,"protein_coding",256148,"OR4S1",4.61719061361746E-3,0.795797779,7,6.242,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs7124275;rs4752891;rs374209699;rs56692100:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",33]
["ENSG00000176547","OR4C3",11,48346472,48347507,1,"protein_coding",256144,"OR4C3",0.00874513097467769,0.097057746,3,2.329,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs7124275;rs4752891;rs374209699;rs56692100:rs374209699:rs374209699;rs7124275:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275",33]
["ENSG00000176540","OR4C5",11,48387037,48388017,-1,"protein_coding",79346,"OR4C5",0.0165676629621224,"NA",10,16.87,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs374209699;rs7124275;rs56692100;rs4752891;rs56692100:rs374209699;rs7124275:rs4752891:rs7124275;rs56692100:rs7124275:rs56692100:rs374209699",33]
["ENSG00000237388","OR4A47",11,48510269,48511332,1,"protein_coding",403253,"OR4A47",{"v":1.43390782604699E-5,"d":"1.43E-05"},0.482908751,25,13.83,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs374209699;rs7124275;rs56692100;rs4752891;rs56692100:rs4752891:rs7124275:rs7124275;rs56692100:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",33]
["ENSG00000182053","TRIM49B",11,49050504,49059579,1,"protein_coding",283116,"TRIM49B",{"v":7.55661253581996e-05,"d":"7.56E-05"},0.045340655,12,10.93,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Mesendoderm",{"v":1.2E-9,"d":"1.20E-09"},"rs374209699;rs7124275;rs56692100;rs4752891:rs4752891:rs374209699;rs56692100:rs7124275;rs56692100:rs7124275:rs56692100",33]
["ENSG00000214891","TRIM64C",11,49075266,49080664,-1,"protein_coding",646754,"TRIM64C",0.012116567412189,"NA",9,3.852,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Left_Ventricle:Right_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.3E-10,"d":"3.30E-10"},"rs374209699;rs7124275;rs56692100;rs4752891:rs4752891:rs374209699;rs56692100:rs374209699:rs374209699;rs7124275:rs7124275:rs7124275;rs56692100:rs56692100",33]
["ENSG00000086205","FOLH1",11,49168187,49230222,-1,"protein_coding",2346,"FOLH1",0.253396884638148,-0.094158315,1,5.51,890,{"v":1.38876e-14,"d":"1.39E-14"},{"v":5.1261e-17,"d":"5.13E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.3E-10,"d":"3.30E-10"},"rs374209699;rs7124275;rs56692100;rs4752891;rs4752891:rs4752891:rs374209699;rs56692100:rs374209699;rs7124275:rs374209699:rs7124275:rs7124275;rs56692100:rs56692100",33]
["ENSG00000258817","OR4C13",11,49973943,49974971,1,"protein_coding",283092,"OR4C13",{"v":8.59262892850206e-09,"d":"8.59E-09"},0.28692396,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":8.2e-11,"d":"8.20E-11"},"rs374209699;rs7124275;rs56692100:rs4752891:rs7124275;rs56692100:rs7124275:rs56692100:rs7124275;rs4752891:rs374209699;rs7124275:rs374209699",33]
["ENSG00000221954","OR4C12",11,50003009,50004071,-1,"protein_coding",283093,"OR4C12",0.23821319029955,0.040232143,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Bladder:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.3E-10,"d":"3.30E-10"},"rs374209699;rs7124275;rs56692100:rs7124275;rs4752891:rs7124275:rs4752891:rs7124275;rs56692100:rs56692100:rs374209699",33]
["ENSG00000221840","OR4A5",11,51411378,51412448,-1,"protein_coding",81318,"OR4A5","NA",0.038778801,0,0,0,"NA","NA","NA","NA","Yes","Aorta:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":6.8e-09,"d":"6.80E-09"},"rs7124275;rs4752891:rs4752891:rs374209699;rs56692100:rs7124275:rs7124275;rs56692100",33]
["ENSG00000137486","ARRB1",11,74975226,75062873,-1,"protein_coding",408,"ARRB1",0.986801821116486,-0.49885402,0,0,8,{"v":5.38751e-05,"d":"5.39E-05"},0.0390548,"GTEx/v8/Artery_Aorta","-","Yes","EP_correlation_cell_type_oneway",{"v":3.3e-12,"d":"3.30E-12"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133;11:75537738_CT_C",34]
["ENSG00000149243","KLHL35",11,75133438,75141674,-1,"protein_coding",283212,"KLHL35",{"v":1.35038973626761e-12,"d":"1.35E-12"},-0.180877162,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.2e-12,"d":"2.20E-12"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs72997616",34]
["ENSG00000171533","MAP6",11,75297963,75380165,-1,"protein_coding",4135,"MAP6",0.0131669155399533,-1.145656715,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1E-13,"d":"1.10E-13"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs72997616;rs10899133:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672:rs11236508:rs144023941:rs72997616;rs28811614;rs11236508:rs72997616;rs28811614:rs12221567:rs28811614:rs72997616",34]
["ENSG00000166391","MOGAT2",11,75428864,75444003,1,"protein_coding",80168,"MOGAT2",0.218649112879292,0.716784085,29,11.19,7,{"v":6.32497E-6,"d":"6.32E-06"},{"v":1.3234e-06,"d":"1.32E-06"},"GTEx/v8/Liver","+","Yes","Promoter_anchored_loops:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-13,"d":"4.60E-13"},"rs11236508;rs144023941;rs72997616;rs28811614;rs144023941:rs72997616;rs11236508:rs72997616;rs28811614:rs72997616;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs72997616;rs10899133:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672:rs72997616",34]
["ENSG00000062282","DGAT2",11,75470557,75512579,1,"protein_coding",84649,"DGAT2",{"v":7.51042690362332e-08,"d":"7.51E-08"},-0.634945675,56,13.56,0,"NA","NA","NA","NA","No","NA",{"v":1.1E-13,"d":"1.10E-13"},"rs12221567;rs72997616;rs28811614;rs11236508;11:75539742_GTA_G;rs10899133;11:75537738_CT_C",34]
["ENSG00000198382","UVRAG",11,75526212,75854239,1,"protein_coding",7405,"UVRAG",0.858602500357733,-0.177213177,96,16.46,137,{"v":6.1014e-10,"d":"6.10E-10"},{"v":4.39681e-06,"d":"4.40E-06"},"GTEx/v8/Artery_Aorta","-","Yes","EP_correlation_cell_type_oneway:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6E-13,"d":"2.60E-13"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133;11:75537738_CT_C;rs141370279;rs72997672;rs28811614;11:75537738_CT_C:rs72997616;rs10899133:rs72997616",34]
["ENSG00000085741","WNT11",11,75897369,75921780,-1,"protein_coding",7481,"WNT11",0.118580135382174,-0.390232041,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-12,"d":"2.20E-12"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs72997616;rs10899133:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672",34]
["ENSG00000137492","PRKRIR",11,76061000,76092015,-1,"protein_coding",5612,"PRKRIR",0.968969189254267,-0.304434935,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.2e-12,"d":"2.20E-12"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997616;rs10899133:rs72997672",34]
["ENSG00000179240","RP11-111M22.2",11,76092357,76125663,1,"protein_coding",100506127,"GVQW3","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.2e-12,"d":"2.20E-12"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997616;rs10899133:rs72997672",34]
["ENSG00000137507","LRRC32",11,76368568,76381791,-1,"protein_coding",2615,"LRRC32",0.0215755256662984,1.347358259,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.2e-12,"d":"2.20E-12"},"rs72997616;rs11236508;11:75539742_GTA_G;rs10899133:rs72997616;rs10899133;11:75537738_CT_C:rs72997616;rs10899133:rs141370279:rs10899133:11:75537738_CT_C:11:75539742_GTA_G:rs72997672",34]
["ENSG00000166682","TMPRSS5",11,113558272,113577095,-1,"protein_coding",80975,"TMPRSS5",{"v":2.57785706102948E-8,"d":"2.58E-08"},0.18379421,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.8E-21,"d":"2.80E-21"},"rs523980:11:116526032_CCT_C;rs523980:rs516226",35]
["ENSG00000048028","USP28",11,113668596,113746292,-1,"protein_coding",57646,"USP28",0.031657505195455,0.869552466,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.3E-116,"d":"2.30E-116"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs11820589;rs6589563:rs1145208:rs2000571;11:116588375_ATT_A;rs6589568:rs11600380:rs2072560:rs11820589:rs180327:rs3087611:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353",35]
["ENSG00000166736","HTR3A",11,113845603,113861035,1,"protein_coding",3359,"HTR3A",{"v":1.02839422335736E-9,"d":"1.03E-09"},-0.005129549,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":7e-40,"d":"7.00E-40"},"rs761166016;rs12721026;rs145384144:rs688456;rs12721028;rs72127154:rs34416738:rs12721026:rs11216275:rs5072;rs473172:11:116715390_ATAT_A:rs769915248;rs374749810;11:116939899_TTGGG_T:rs72127154:rs35477610;rs5070;rs146811643;rs2735181:rs5070;rs2735181:rs761166016;rs145384144;rs34416738:rs769915248:rs5072;rs90192;rs473172:rs688456;rs72127154;rs11216275;11:116903390_CT_C;rs769915248:rs5070;rs2735181:rs3087611:rs769915248;11:116939899_TTGGG_T:rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118",35]
["ENSG00000109906","ZBTB16",11,113930315,114121398,1,"protein_coding",7704,"ZBTB16",0.980087305825708,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.3E-116,"d":"2.30E-116"},"11:116526032_CCT_C;rs523980:rs61905060:rs545108:rs516226:rs486394:rs523980:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118:rs11820589;rs6589563:rs1145208:rs2000571;11:116588375_ATT_A;rs6589568:rs11600380:rs2072560:rs11820589:rs180327:rs3087611:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353",35]
["ENSG00000166741","NNMT",11,114128509,114184007,1,"protein_coding",4837,"NNMT",0.00427916395502723,-0.273618136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118:rs34416738:rs761166016;rs12721026;rs145384144:rs35477610;rs5070;rs146811643;rs2735181:rs5072;rs473172:rs545274:11:116715390_ATAT_A:rs688456;rs12721028;rs72127154:rs118138924:rs769915248;rs374749810;11:116939899_TTGGG_T:rs3087611:rs35477610;rs2735181;rs761166016;rs145384144:rs473172:rs5072;rs90192;rs473172:rs688456;rs72127154;rs11216275;rs145384144:rs12721026:rs12721026;rs145384144:rs769915248;rs374749810:rs10892078;rs11216164:rs12721040:rs1784118:rs57984552;rs11601584:rs17092642;rs2000571;rs11601584:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs2072560:rs67120644:11:116588375_ATT_A:rs1145208:rs6589563:rs1145208;rs1263056:rs61905077:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs11820589:rs964184;rs11604424:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs508487;rs236911:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs236911:rs236913:rs186782888:rs2735181:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs181009570:rs2735181;rs236913:rs522645:rs2041967:rs7118999:rs964184:rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs2239013:rs5070;rs2735181:rs368142965:rs688456;rs11216275:rs12366015:rs2735181;rs769915248;rs374749810:11:116903390_CT_C:rs688456;11:116903390_CT_C;rs769915248:rs12721028",35]
["ENSG00000180425","C11orf71",11,114262165,114271139,-1,"protein_coding",54494,"C11orf71",0.00842481501256066,-0.124748547,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118:rs1784118:rs57984552;rs11601584:rs17092642;rs2000571;rs11601584:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs2072560:rs67120644:11:116588375_ATT_A:rs1145208:rs6589563:rs1145208;rs1263056:rs61905077:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs11820589:rs3087611:rs964184;rs11604424:rs12721040:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs2041967:rs7118999:rs964184:rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs12721026;rs145384144:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs236911:rs236913:rs186782888:rs2735181:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs377371164",35]
["ENSG00000076053","RBM7",11,114270752,114284925,1,"protein_coding",10179,"RBM7",0.769935289328386,-0.240422903,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118:rs1784118:rs57984552;rs11601584:rs17092642;rs2000571;rs11601584:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs2072560:rs67120644:11:116588375_ATT_A:rs1145208:rs6589563:rs1145208;rs1263056:rs61905077:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs11820589:rs3087611:rs964184;rs11604424:rs12721040:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs2041967:rs7118999:rs964184:rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs12721026;rs145384144:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs236911:rs236913:rs186782888:rs2735181:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs377371164",35]
["ENSG00000255663","RP11-212D19.4",11,114271404,114314654,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118:rs1784118:rs57984552;rs11601584:rs17092642;rs2000571;rs11601584:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs2072560:rs67120644:11:116588375_ATT_A:rs1145208:rs6589563:rs1145208;rs1263056:rs61905077:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327:rs11600380:rs11820589:rs3087611:rs964184;rs11604424:rs12721040:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs2041967:rs7118999:rs964184:rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs12721026;rs145384144:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs236911:rs236913:rs186782888:rs2735181:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs377371164",35]
["ENSG00000076043","REXO2",11,114310108,114321001,1,"protein_coding",25996,"REXO2",0.888428672321779,-0.470637003,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs11820589;rs6589563:rs1145208:rs2000571;11:116588375_ATT_A;rs6589568:rs11600380:rs2072560:rs11820589:rs180327:rs3087611:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs1263056;rs1784118:rs1784118:rs57984552;rs11601584:rs61905060:rs758044300:rs17092642;rs2000571;rs11601584:rs57984552:rs1784118;rs558056:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs11824135;rs61905060:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs11822160:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642;rs2000571:rs2000571;11:116588375_ATT_A:11:116588375_ATT_A:rs6589563:rs1145208;rs1263056:rs61905077:rs141414463:rs2041967:rs7118999:rs964184:rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013",35]
["ENSG00000095110","NXPE1",11,114392437,114430617,-1,"protein_coding",120400,"NXPE1",{"v":3.48609216284613e-10,"d":"3.49E-10"},0.560244834,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":2.8E-21,"d":"2.80E-21"},"rs523980:11:116526032_CCT_C;rs523980:rs516226",35]
["ENSG00000137634","NXPE4",11,114441313,114466484,-1,"protein_coding",54827,"NXPE4",{"v":2.74741341116275e-08,"d":"2.75E-08"},-0.225836593,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesenchymal_Stem_Cell",{"v":2.8E-21,"d":"2.80E-21"},"rs523980:11:116526032_CCT_C;rs523980:rs516226",35]
["ENSG00000204361","NXPE2",11,114549108,114579362,1,"protein_coding",120406,"NXPE2",0.244911849376349,-0.045975215,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118:rs1784118:rs57984552;rs11601584:rs17092642;rs2000571;rs11601584:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs2000571:rs2000571;11:116588375_ATT_A:rs2072560:rs67120644:11:116588375_ATT_A:rs1145208:rs6589563:rs1145208;rs1263056:rs61905077:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327",35]
["ENSG00000182985","CADM1",11,115039938,115375675,-1,"protein_coding",23705,"CADM1",0.99438640410443,-1.276282249,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7e-40,"d":"7.00E-40"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs61905060:rs545108:rs486394:11:116526032_CCT_C:rs57984552:rs11824135;rs61905060:rs17092642:rs2186670:rs17092642;rs2000571:rs1784118;rs558056:rs11820504:rs558056:rs509728:rs486915:rs11822160:rs150750906:rs11824135;rs61905060;rs17092642;rs2000571:rs758044300:rs11824135:rs11828763:rs1263056;rs1784118",35]
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["ENSG00000109917","ZNF259",11,116648436,116658766,-1,"protein_coding",8882,"ZNF259",0.0193034953229086,0.002394641,52,23.3,50,{"v":3.77408e-06,"d":"3.77E-06"},0.000361971,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.5e-121,"d":"9.50E-121"},"11:116638691_AAAT_A;rs2072560;rs1268353;rs1145208;rs1263056;rs67120644;rs2041967;rs7118999;rs3087611;rs12721040;rs11600380;rs11820589;rs964184;rs11604424;rs6589567;rs758044300;rs6589563;rs1729408;rs525302;rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs769915248;rs374749810;11:116939899_TTGGG_T:rs34416738:rs761166016;rs12721026;rs145384144:rs769915248;rs374749810:11:116715390_ATAT_A;rs2075547:rs90192;rs473172;rs11449159;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:11:116715390_ATAT_A:rs12721028;rs11216275:rs11216275;rs769915248:rs5072;rs473172:rs11216275:rs10892078;rs11216164:rs5072;rs90192;rs236911:rs34796476:rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:rs2735181:11:116999722_TA_T;rs58065809:rs145384144:rs58065809:rs1263169:rs10892035;rs200839648:rs1263167:rs10892035:rs200839648:rs5130;rs10892035:rs525028:11:116715390_ATAT_A;rs12721028:rs688456;rs769915248;11:116939899_TTGGG_T:rs525302:rs6144523:rs525028;rs35477610;rs5070;rs6144523;rs2735181;11:116715350_AT_A:11:116715350_AT_A:rs12721026;rs145384144:rs595137:rs688456;11:116715390_ATAT_A;rs12721028;rs72127154:rs688456;rs72127154:rs5072:rs525028;11:116715350_AT_A:rs545274:rs35477610;rs2735181:rs525028;rs2735181:11:116733789_CA_C:rs11216164:rs5072;rs473172:rs12721026:rs35477610;rs146811643;rs2735181:11:116715390_ATAT_A;rs141594094:rs473172:rs4938316:rs3087611:rs90192:rs61905077:rs35477610:rs688456;11:116939899_TTGGG_T:rs12721040:rs5070;rs2735181:rs688456;rs11216275;rs761166016;rs145384144:rs688456;rs769915248:rs688456;rs11216275:rs688456;rs11449159:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs5070;rs12366015;rs2735181:rs473172;rs11449159:11:116999722_TA_T:rs90192;11:116999722_TA_T;rs58065809:rs5072;rs236911:rs118138924:rs61905077;rs28917234:rs11820589;rs6589563:rs1145208:rs2000571;11:116588375_ATT_A;rs6589568:rs11600380:rs2072560:rs11820589:rs508487;rs236911:rs90192;11:116999722_TA_T:rs508487:rs5070;rs374749810:rs688456:rs688456;11:116733789_CA_C;rs769915248:rs761166016;rs145384144;rs34416738:rs769915248:rs769915248;11:116939899_TTGGG_T:11:116715390_ATAT_A;rs72127154:11:116927252_GATAGAT_G:11:116939899_TTGGG_T:rs761166016:rs688456;rs145384144:rs763583827:rs90192;rs58065809:rs11449159:rs180327:rs964184;rs11604424:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs141594094:rs374749810:rs35477610;rs145384144:rs368142965:rs2735181;rs374749810:11:116903390_CT_C:rs508487;rs236911:rs236911:rs236913:rs186782888:rs181009570:rs2735181;rs236913:rs522645:rs377371164:rs28917234",35]
["ENSG00000110243","APOA5",11,116660083,116663136,-1,"protein_coding",116519,"APOA5",{"v":1.37735073361006e-06,"d":"1.38E-06"},0.423730278,44,23.3,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Hippocampus:Left_Ventricle:Liver:Pancreas:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3E-116,"d":"2.30E-116"},"rs11820589;rs11600380;rs11604424;rs2072560;rs3087611;rs1145208;rs964184;rs7118999;rs6589567;rs6589568;rs67120644;rs2070669:rs34416738:rs1263167:rs10892035;rs200839648:rs525028:rs12721028:rs5130;rs5072:rs5130:rs3087611:rs525028;rs5070:rs5130;rs10892035;rs5072:rs688456;rs12721028:rs12721026:rs12721026;rs145384144:rs5072:rs5070:11:116715390_ATAT_A;rs12721028:rs35477610;rs5070;rs146811643;rs2735181:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs12721028;rs11216275:rs761166016;rs12721026;rs145384144:rs688456;rs11216275;rs769915248:rs769915248;rs374749810;11:116939899_TTGGG_T:rs5072;rs473172:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:11:116715390_ATAT_A:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs769915248;rs374749810:rs5072;rs11449159;rs236911:11:116715390_ATAT_A;rs2075547:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;rs2735181;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs5070;rs2735181:rs525028;rs12366015;rs2735181:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs61905077:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs2075547:rs58065809;11:116715350_AT_A:rs2735181:rs145384144:rs58065809:rs90192;11:116999722_TA_T;rs58065809:rs508487;rs236911:rs90192;rs236911:rs236911:rs236913:rs186782888:rs5072;rs236911:rs118138924:rs508487;rs236911:rs90192:rs90192;11:116999722_TA_T:rs508487:rs5070;rs374749810:rs525028;rs35477610;rs6144523;11:116715350_AT_A:11:116715350_AT_A:rs688456:rs525302:rs688456;11:116715390_ATAT_A;rs72127154:rs595137:rs688456;rs12721028:rs525028;11:116733789_CA_C;rs769915248:rs525028;11:116715350_AT_A:rs545274:rs35477610;rs2735181:11:116733789_CA_C:rs11216164:rs5072;rs473172:rs688456;rs72127154:11:116715390_ATAT_A;rs141594094:rs5070;rs2735181:rs761166016;rs145384144;rs34416738:rs769915248:rs688456;rs761166016;11:116939899_TTGGG_T:11:116715390_ATAT_A;rs72127154:11:116927252_GATAGAT_G:11:116939899_TTGGG_T:rs761166016:rs688456;rs145384144:rs763583827:rs90192;rs58065809:rs11449159:rs11820589;rs6589563:rs1145208:rs2000571;11:116588375_ATT_A;rs6589568:rs11600380:rs2072560:rs11820589:rs180327:rs964184;rs11604424:rs12721040:rs67120644:rs143811287:rs17440824:11:116638691_AAAT_A:rs1268353:rs473172:rs4938316:rs35477610:rs688456;rs769915248;11:116939899_TTGGG_T:rs141594094:rs374749810:rs35477610;rs145384144:rs368142965:rs2735181;rs374749810:11:116903390_CT_C:rs181009570:rs2735181;rs236913:rs522645:rs377371164:rs61905077;rs28917234:rs28917234",35]
["ENSG00000110244","APOA4",11,116691419,116694022,-1,"protein_coding",337,"APOA4",{"v":3.57595118139907e-05,"d":"3.58E-05"},0.081655096,54,23.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.2e-66,"d":"2.20E-66"},"rs34416738;rs10892035;rs200839648;rs1263169;rs1263167;rs12721040;rs2239013;rs140231532;rs61905077;rs2070669;rs525028;rs12721028;rs5130;rs5072;rs3087611;rs5070;rs10892035:rs525028:11:116715390_ATAT_A;rs12721028:rs688456;rs769915248;11:116939899_TTGGG_T:rs525302:11:116715390_ATAT_A:rs6144523:rs525028;rs35477610;rs6144523;rs2735181;11:116715350_AT_A:11:116715350_AT_A:rs12721026;rs145384144:rs595137:rs688456;11:116715390_ATAT_A;rs72127154:rs34416738:rs688456;rs72127154:rs35477610;rs146811643;rs2735181:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs11216275:rs761166016;rs12721026;rs145384144:rs688456;rs11216275;rs769915248:rs769915248;rs374749810;11:116939899_TTGGG_T:rs5072;rs473172:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs769915248;rs374749810:rs5072;rs11449159;rs236911:11:116715390_ATAT_A;rs2075547:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs146811643:rs12366015:rs5070;rs2735181:rs525028;rs12366015;rs2735181:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs61905077:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs2735181:rs58065809:rs2075547:rs90192;11:116999722_TA_T;rs58065809:rs508487:rs58065809;11:116715350_AT_A:rs90192;rs58065809:rs145384144:rs11449159",35]
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["ENSG00000149577","SIDT2",11,117049449,117068160,1,"protein_coding",51092,"SIDT2",0.00257240105871232,-0.315317931,101,21.8,700,{"v":9.00793e-29,"d":"9.01E-29"},{"v":1.17121e-22,"d":"1.17E-22"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","Yes","EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.5e-121,"d":"9.50E-121"},"rs761166016;rs12721026;rs145384144;rs90192;rs473172;11:116999722_TA_T;rs58065809;rs2735181;rs34416738;rs11449159;rs236911;rs10892078;rs2075547;rs5072;rs508487;11:116715390_ATAT_A;rs118138924;11:116715350_AT_A;rs688456;rs12721028;rs525028;rs72127154;rs11216275;11:116733789_CA_C;11:116903390_CT_C;rs769915248;rs10892035;rs200839648;rs5130;rs2239013;rs3087611;rs374749810;rs1145208;rs1263169;rs2070669;rs5070;rs35477610;rs6144523;rs11216164;rs146811643;11:116984726_CA_C;rs145384144:11:116999722_TA_T;11:116715350_AT_A:rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs10892035:rs200839648:rs5130;rs10892035:rs525028:11:116715390_ATAT_A;rs12721028:rs688456;11:116939899_TTGGG_T:rs525302:11:116715390_ATAT_A:rs6144523:rs525028;11:116715350_AT_A:11:116715350_AT_A:rs12721026;rs145384144:rs595137:rs688456;rs72127154:rs688456;rs72127154:rs5072:rs525028;11:116715350_AT_A:rs545274:rs5072;rs473172:rs35477610;rs2735181:rs525028;rs2735181:11:116733789_CA_C:rs11216164:rs5072;rs473172:rs12721026:rs35477610;rs2735181:11:116715390_ATAT_A;rs141594094:rs473172:rs4938316:rs90192:rs61905077:rs35477610:rs688456;11:116939899_TTGGG_T:rs769915248;rs374749810:rs769915248;11:116939899_TTGGG_T:rs11216275:rs5070;rs2735181:rs688456;rs145384144:rs688456;rs769915248:rs5070;rs2735181:rs769915248;11:116939899_TTGGG_T:rs688456;rs11216275:rs688456;rs769915248:11:116939899_TTGGG_T:rs688456;rs11216275:rs5072;rs11449159:rs12721028;rs11216275:rs11216275;rs769915248:rs10892078;rs11216164:rs5072;rs236911:11:116715390_ATAT_A;rs2075547:rs34796476:rs146811643:rs12366015:rs525028;rs12366015;rs2735181:rs473172;rs11449159:rs10892078:rs12721028;rs72127154:rs90192;rs236911:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs2075547:rs58065809;11:116715350_AT_A:rs2735181:rs145384144:rs58065809:rs90192;11:116999722_TA_T:rs508487:rs61905077;rs28917234:rs28917234:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs2239013:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs688456:rs688456;rs769915248:rs769915248:rs141594094:rs118138924:rs374749810:rs72127154:rs761166016;rs34416738:rs90192;rs58065809:rs90192;rs58065809:rs11449159:rs35477610;rs145384144:rs5072;rs90192:11:116984726_CA_C:rs5070",35]
["ENSG00000149591","TAGLN",11,117070037,117075498,1,"protein_coding",6876,"TAGLN",0.241537680178233,-0.645790474,73,21.8,303,{"v":3.70697E-19,"d":"3.71E-19"},{"v":7.71611E-14,"d":"7.72E-14"},"GTEx/v8/Pancreas","-","Yes","EP_links_oneway:Promoter_anchored_loops:Adult_Cortex:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.5e-121,"d":"9.50E-121"},"rs761166016;rs12721026;rs145384144;rs34416738;rs90192;rs473172;11:116999722_TA_T;rs58065809;rs508487;rs11449159;rs236911;rs2075547;11:116715350_AT_A;rs10892078;rs1263169;rs10892035;rs200839648;rs5130;rs525028;rs5070;rs5072;rs35477610;rs6144523;rs2735181;rs11216164;rs146811643;11:116984726_CA_C;rs236913;rs145384144:rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs6589567:rs6589568:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013:rs10892035:rs200839648:rs688456;rs12721028;rs72127154:rs35477610;rs2735181:11:116715390_ATAT_A;rs141594094:rs595137:rs5072;rs473172:rs10892078;rs11216164:11:116715350_AT_A:rs761166016;rs145384144:rs2735181:11:116999722_TA_T:rs58065809:rs2075547:11:116999722_TA_T;11:116715350_AT_A:rs90192;rs236911:rs90192;rs58065809:rs10892078:rs508487:rs58065809;rs58065809:rs5072:rs525028;11:116715350_AT_A:rs545274:rs5072;rs473172:rs525302:11:116715390_ATAT_A:rs525028;rs2735181:11:116733789_CA_C:rs11216164:rs5072;rs236911:rs118138924:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs525028;11:116715350_AT_A:rs688456:rs688456;11:116715390_ATAT_A;rs72127154:rs525028:rs688456;rs12721028:rs688456;rs72127154;rs11216275:rs688456;11:116733789_CA_C;11:116903390_CT_C;rs11216275;rs769915248:rs12721026:rs35477610;rs2735181:rs473172:rs4938316:rs90192:rs61905077:rs35477610:rs688456;rs769915248;rs374749810;11:116939899_TTGGG_T:rs769915248;rs374749810:rs769915248:rs141594094:rs374749810:rs11216275:rs769915248;11:116939899_TTGGG_T:rs72127154:rs5070;rs2735181:rs761166016;rs34416738:rs688456;rs145384144:rs688456;rs769915248:rs5070;rs2735181:rs769915248;11:116939899_TTGGG_T:rs473172;11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs145384144:rs11449159:rs35477610;rs769915248:rs5072;rs11449159:rs12721028;rs11216275:rs11216275;rs236911:11:116715390_ATAT_A;rs2075547:rs34796476:rs12721028;rs72127154:rs5072;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs146811643:rs12366015:rs525028;rs12366015;rs2735181:rs473172",35]
["ENSG00000160613","PCSK7",11,117075053,117103241,-1,"protein_coding",9159,"PCSK7",0.191369613352617,"NA",97,21.8,70,{"v":1.9685e-11,"d":"1.97E-11"},{"v":3.95162E-7,"d":"3.95E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.5e-121,"d":"9.50E-121"},"rs761166016;rs12721026;rs145384144;rs34416738;rs10892078;11:116999722_TA_T;rs58065809;11:116715350_AT_A;rs90192;rs473172;rs2075547;rs508487;rs236911;rs236913;rs186782888;rs2735181;rs181009570;rs522645;rs595137;rs545274;rs118138924;rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs10892035:rs200839648:rs35477610;rs5070;rs146811643;rs2735181:rs761166016;rs145384144:rs5072;rs473172:rs688456;rs12721028;rs72127154:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs11216275;rs769915248:rs769915248;rs374749810;11:116939899_TTGGG_T:rs5072;rs11449159:rs12721028;rs11216275:11:116715390_ATAT_A:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs769915248;rs374749810:rs5072;rs11449159;rs236911:11:116715390_ATAT_A;rs2075547:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs12721026;rs145384144:rs146811643:rs12366015:rs5070;rs2735181:rs525028;rs12366015;rs2735181:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;11:116715350_AT_A:rs61905077:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs2239013:rs377371164:rs61905077;rs28917234:rs28917234:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs525028;rs35477610;rs6144523;11:116715350_AT_A:11:116715350_AT_A:rs688456:rs525302:rs688456;11:116715390_ATAT_A;rs72127154:rs595137:rs525028:rs688456;rs12721028:rs525028;rs2735181:rs688456;11:116733789_CA_C;rs769915248:rs5072:rs525028;11:116715350_AT_A:rs545274:rs35477610;rs2735181:11:116733789_CA_C:rs11216164:rs5072;rs473172:11:116715390_ATAT_A;rs141594094:rs12721026:rs473172:rs4938316:rs90192:rs35477610:rs688456;rs769915248;11:116939899_TTGGG_T:rs769915248:rs141594094:rs118138924:rs374749810:rs35477610;rs145384144:rs688456",35]
["ENSG00000167257","RNF214",11,117103341,117157161,1,"protein_coding",257160,"RNF214",0.830018244677536,"NA",15,18.5,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.5e-121,"d":"9.50E-121"},"rs2075547;rs12721026;rs145384144;rs2735181;rs181009570;rs34416738;rs236913;rs522645;rs377371164;rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs10892035:rs200839648:rs35477610;rs5070;rs146811643;rs2735181:rs761166016;rs145384144:rs5072;rs473172:rs688456;rs12721028;rs72127154:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs11216275;rs769915248:rs769915248;rs374749810;11:116939899_TTGGG_T:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:11:116715390_ATAT_A:rs11216275;rs769915248:rs11216275:rs10892078;rs11216164:rs769915248;rs374749810:rs5072;rs11449159;rs236911:11:116715390_ATAT_A;rs2075547:rs34796476:rs12721028;rs72127154:rs10892078:rs5072;rs508487;rs90192:11:116984726_CA_C:rs5070;11:116984726_CA_C:rs72127154:rs12721026;rs145384144:rs146811643:rs12366015:rs5070;rs2735181:rs525028;rs12366015;rs2735181:rs473172;rs11449159:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs61905077:rs473172;11:116999722_TA_T:11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs2239013:rs377371164:rs61905077;rs28917234:rs28917234:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353:rs5070;rs374749810:rs525028;rs35477610;rs6144523;11:116715350_AT_A:11:116715350_AT_A:rs688456:rs525302:rs688456;11:116715390_ATAT_A;rs72127154:rs595137:rs525028:rs688456;rs12721028:rs525028;rs2735181:rs688456;11:116733789_CA_C;rs769915248:rs5072:rs525028;11:116715350_AT_A:rs545274:rs35477610;rs2735181:11:116733789_CA_C:rs11216164:rs5072;rs473172:11:116715390_ATAT_A;rs141594094:rs12721026:rs473172:rs4938316:rs90192:rs35477610:rs688456;rs769915248;11:116939899_TTGGG_T:rs769915248:rs141594094:rs118138924:rs374749810:rs35477610;rs761166016;rs145384144:rs688456",35]
["ENSG00000186318","BACE1",11,117156402,117186975,-1,"protein_coding",23621,"BACE1",0.944278809144277,-0.919089932,3,17.44,0,"NA","NA","NA","NA","Yes","EP_correlation_organ_oneway:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs377371164;rs61905077;rs28917234;rs761166016;rs12721026;rs145384144:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs90192;rs473172;rs11449159;rs236911:rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:rs2735181:rs34416738:11:116999722_TA_T;rs58065809:rs145384144:rs58065809:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs5072;rs508487;rs90192;rs236911:11:116715390_ATAT_A:rs118138924:rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs2239013:rs508487;rs236911:rs90192;rs236911:rs236911:rs236913:rs186782888:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs377371164",35]
["ENSG00000110274","CEP164",11,117185273,117283984,1,"protein_coding",22897,"CEP164",{"v":9.66879225304467e-18,"d":"9.67E-18"},0.753351641,2,17.44,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs61905077;rs28917234;rs761166016;rs12721026;rs145384144:rs2075547:rs90192;rs473172;rs11449159;rs236911:rs58065809;11:116715350_AT_A:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:rs2735181:rs34416738:11:116999722_TA_T;rs58065809:rs145384144:rs58065809:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs5072;rs508487;rs90192;rs236911:11:116715390_ATAT_A:rs118138924:rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs2239013:rs508487;rs236911:rs90192;rs236911:rs236911:rs236913:rs186782888:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs377371164",35]
["ENSG00000137747","TMPRSS13",11,117771358,117800174,-1,"protein_coding",84000,"TMPRSS13",{"v":6.08622571727962e-05,"d":"6.09E-05"},2.053021914,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.6e-09,"d":"2.60E-09"},"rs377371164",35]
["ENSG00000110324","IL10RA",11,117857063,117872196,1,"protein_coding",3587,"IL10RA",0.968345855815418,-0.921352137,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.8E-21,"d":"2.80E-21"},"rs523980:11:116526032_CCT_C;rs523980:rs516226",35]
["ENSG00000137648","TMPRSS4",11,117947753,117992605,1,"protein_coding",56649,"TMPRSS4",{"v":1.19754386539244e-08,"d":"1.20E-08"},0.384951766,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.3E-51,"d":"1.30E-51"},"rs523980:11:116526032_CCT_C;rs523980:rs516226:rs1263056;rs1784118:rs1784118:rs57984552;rs11601584:rs61905060:rs758044300:rs17092642;rs2000571;rs11601584:rs57984552:rs1784118;rs558056:rs2000571;rs11601584:rs11601584:11:116569272_TA_T:rs11824135;rs61905060:rs879858:rs1263056:rs1145208;rs1263056;rs1784118:rs11822160:rs12221682:rs61905067:rs11216107:rs2000571:rs11820589;rs6589563;rs61905060:rs7118999;rs57984552;rs11216107;rs17092642;rs2000571:rs2000571;11:116588375_ATT_A:rs2072560:rs67120644:11:116588375_ATT_A:rs1145208:rs6589563:rs1145208;rs1263056:rs61905077:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs141414463:rs180327",35]
["ENSG00000110344","UBE4A",11,118230300,118269926,1,"protein_coding",9354,"UBE4A",0.937619432134248,0.396074413,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4e-32,"d":"1.40E-32"},"rs34416738:rs35477610;rs5070;rs146811643;rs2735181:rs688456;rs72127154;11:116903390_CT_C;rs11216275:rs688456;rs12721028;rs11216275:rs761166016;rs12721026;rs145384144:rs688456;rs11216275;rs769915248:rs769915248;rs374749810;11:116939899_TTGGG_T:rs5072;rs473172:rs5072;rs90192;rs473172;rs11449159:rs12721028;rs11216275:rs2735181:rs90192;rs11449159;rs236911:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs2075547:rs5072;rs508487;rs236911:11:116715390_ATAT_A:rs118138924:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs58065809;11:116715350_AT_A:rs473172;11:116999722_TA_T:11:116999722_TA_T;rs58065809:rs145384144:rs58065809",35]
["ENSG00000254873","RP11-770J1.5",11,118267810,118272610,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs12721026;rs145384144:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs236911:rs236913:rs186782888:rs2735181:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs61905077;rs28917234:rs28917234:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353",35]
["ENSG00000167283","ATP5L",11,118271869,118302211,1,"protein_coding",10632,"ATP5L",0.337891181698725,-0.416063281,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":9.5e-121,"d":"9.50E-121"},"rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013:rs508487;rs90192;rs236911:rs761166016;rs12721026;rs145384144:rs90192;rs236911:11:116999722_TA_T;rs58065809;11:116715350_AT_A:rs2075547:rs236911:rs236913:rs186782888:rs2735181:rs90192;rs473172;11:116999722_TA_T;rs58065809:rs12721026;rs145384144:rs181009570:rs2735181;rs236913:rs522645:rs61905077;rs28917234:rs28917234:rs11820589;rs6589563:rs2000571;11:116588375_ATT_A;rs6589568:rs180327:rs17440824:11:116638691_AAAT_A:rs1268353",35]
["ENSG00000255384","RP11-770J1.4",11,118303836,118305921,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":9.5e-121,"d":"9.50E-121"},"rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013",35]
["ENSG00000118058","KMT2A",11,118307205,118397539,1,"protein_coding",4297,"KMT2A",1,-1.788949198,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":9.5e-121,"d":"9.50E-121"},"rs2072560:rs1145208;rs1263056:rs1145208:rs67120644:rs2041967:rs7118999:rs3087611:rs12721040:rs11600380:rs11820589:rs964184:rs11604424:rs964184;rs11604424:rs2072560;rs6589567:rs6589568:rs6589567:rs143811287:rs1729408:rs1263169:rs10892035;rs200839648:rs1263167:rs34416738:rs2239013",35]
["ENSG00000149582","TMEM25",11,118401756,118417995,1,"protein_coding",84866,"TMEM25",0.00042136891544107,1.146697877,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.6E-27,"d":"8.60E-27"},"rs2735181:rs761166016;rs12721026;rs145384144:rs34416738:rs90192;rs473172;rs11449159;rs236911:rs10892078:rs90192;11:116999722_TA_T;rs58065809:rs2075547:rs5072;rs508487;rs90192;rs236911:11:116715390_ATAT_A:rs118138924:11:116999722_TA_T;rs58065809;11:116715350_AT_A",35]
["ENSG00000136045","PWP1",12,108079509,108106944,1,"protein_coding",11137,"PWP1",{"v":1.8549631577177e-05,"d":"1.85E-05"},-0.171875533,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":8.6e-09,"d":"8.60E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212",36]
["ENSG00000110851","PRDM4",12,108126643,108155049,-1,"protein_coding",11108,"PRDM4",0.833196847904435,-0.18119585,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":7.4e-09,"d":"7.40E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212",36]
["ENSG00000075035","WSCD2",12,108523248,108644314,1,"protein_coding",9671,"WSCD2",0.494025684101003,1.171623886,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.3E-5,"d":"2.30E-05"},"rs7973253",36]
["ENSG00000174600","CMKLR1",12,108681821,108733118,-1,"protein_coding",1240,"CMKLR1",0.0685269634408008,0.847161487,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":8.6e-09,"d":"8.60E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212",36]
["ENSG00000075856","SART3",12,108916357,108955176,-1,"protein_coding",9733,"SART3",0.991709384753294,-0.230330092,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:12:109958548_AT_A",36]
["ENSG00000136003","ISCU",12,108956358,108963160,1,"protein_coding",23479,"ISCU",0.135947771003731,0.494530457,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:12:109958548_AT_A",36]
["ENSG00000110876","SELPLG",12,109015686,109027735,-1,"protein_coding",6404,"SELPLG",0.00495442531161246,0.826234123,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7.4e-09,"d":"7.40E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212",36]
["ENSG00000084112","SSH1",12,109176466,109251366,-1,"protein_coding",54434,"SSH1",0.987158740858356,-2.011808117,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7.4e-09,"d":"7.40E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212",36]
["ENSG00000110887","DAO",12,109252708,109294819,1,"protein_coding",1610,"DAO",{"v":9.26248223544675e-15,"d":"9.26E-15"},0.031721518,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":7.4e-09,"d":"7.40E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212",36]
["ENSG00000166111","SVOP",12,109304658,109459045,-1,"protein_coding",55530,"SVOP","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.3e-08,"d":"1.30E-08"},"rs71079573;rs2241212:rs7973253",36]
["ENSG00000135093","USP30",12,109460894,109525831,1,"protein_coding",84749,"USP30",0.309014179184126,-0.709413278,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.3E-5,"d":"2.30E-05"},"rs7973253",36]
["ENSG00000189046","ALKBH2",12,109525996,109531436,-1,"protein_coding",121642,"ALKBH2",0.000816686414241077,-0.248281919,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:12:109958548_AT_A",36]
["ENSG00000076248","UNG",12,109535379,109548797,1,"protein_coding",7374,"UNG",0.0465811527139078,-1.048065563,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:12:109958548_AT_A",36]
["ENSG00000076555","ACACB",12,109554400,109706031,1,"protein_coding",32,"ACACB",{"v":5.12432725817776e-22,"d":"5.12E-22"},0.136952699,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:12:109958548_AT_A",36]
["ENSG00000139445","FOXN4",12,109715784,109747025,-1,"protein_coding",121643,"FOXN4",0.133060550432118,-0.465356883,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-08,"d":"1.30E-08"},"rs71079573;rs2241212:rs7973253",36]
["ENSG00000174527","MYO1H",12,109785708,109893328,1,"protein_coding",283446,"MYO1H",{"v":2.91611360098295e-17,"d":"2.92E-17"},0.269947126,88,12.85,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.7e-09,"d":"5.70E-09"},"rs7973253;rs71079573;rs2241212;rs7973253:rs71079573;rs2241212:rs7973253",36]
["ENSG00000110906","KCTD10",12,109886461,109915349,-1,"protein_coding",83892,"KCTD10",0.17266981342374,0.585872566,25,10.53,11,{"v":2.78235e-05,"d":"2.78E-05"},{"v":1.43418e-21,"d":"1.43E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253;rs71079573;rs2241212;rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:rs71079573;rs2241212:12:109958548_AT_A",36]
["ENSG00000151148","UBE3B",12,109915207,109974507,1,"protein_coding",89910,"UBE3B",0.00938770579237683,0.786225851,25,21.8,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs7973253;rs2241212;rs71079573;12:109958548_AT_A;rs7973253:rs71079573;rs2241212:rs7973253;rs2241212:rs2241212:rs71079573;rs2241212:12:109958548_AT_A",36]
["ENSG00000139428","MMAB",12,109991542,110011679,-1,"protein_coding",326625,"MMAB",0.00387716022324201,2.918192677,29,12.59,135,{"v":5.15399e-12,"d":"5.15E-12"},{"v":2.27735e-08,"d":"2.28E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs71079573;rs2241212;rs7973253;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212",36]
["ENSG00000110921","MVK",12,110011060,110035067,1,"protein_coding",4598,"MVK",0.0421613966473064,-0.508881997,17,9.067,54,{"v":1.30846E-5,"d":"1.31E-05"},0.036112,"GTEx/v8/Liver","-","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs71079573;rs2241212;rs7973253;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212",36]
["ENSG00000139438","FAM222A",12,110152033,110208312,1,"protein_coding",84915,"FAM222A",0.400389071715135,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":1.1e-09,"d":"1.10E-09"},"rs71079573;rs2241212:rs7973253;rs2241212:12:109958548_AT_A:rs7973253:rs2241212",36]
["ENSG00000111199","TRPV4",12,110220890,110271212,-1,"protein_coding",59341,"TRPV4",{"v":7.31947219105235e-06,"d":"7.32E-06"},-0.738970458,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Spleen:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.1e-09,"d":"1.10E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212:12:109958548_AT_A",36]
["ENSG00000139433","GLTP",12,110288748,110318293,-1,"protein_coding",51228,"GLTP",0.22708870640821,0.063857559,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell",{"v":7.4e-09,"d":"7.40E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212",36]
["ENSG00000139437","TCHP",12,110338069,110421646,1,"protein_coding",84260,"TCHP",{"v":6.99625064835171e-12,"d":"7.00E-12"},-0.572434138,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.3e-08,"d":"1.30E-08"},"rs71079573;rs2241212",36]
["ENSG00000139436","GIT2",12,110367607,110434194,-1,"protein_coding",9815,"GIT2",0.970632700807013,-0.942959049,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212",36]
["ENSG00000076513","ANKRD13A",12,110436991,110477568,1,"protein_coding",88455,"ANKRD13A",0.350624808697698,-0.732035314,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":8.6e-09,"d":"8.60E-09"},"rs71079573;rs2241212:rs7973253:rs7973253;rs2241212:rs2241212",36]
["ENSG00000196510","ANAPC7",12,110810705,110841535,-1,"protein_coding",51434,"ANAPC7",0.999257869586772,-0.621643021,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.2e-10,"d":"6.20E-10"},"rs4766578",37]
["ENSG00000111231","GPN3",12,110890289,110907073,-1,"protein_coding",51184,"GPN3",1.00471691467198E-4,-0.618749154,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8e-12,"d":"8.00E-12"},"rs4766578:rs570920196:rs71079573;rs2241212:rs4766578;rs11066320;rs570920196",1.5256944444444445]
["ENSG00000204856","FAM216A",12,110906169,110928190,1,"protein_coding",29902,"FAM216A",0.0011162985137716,-0.854490491,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":8e-12,"d":"8.00E-12"},"rs4766578:rs570920196:rs71079573;rs2241212:rs4766578;rs11066320;rs570920196",1.5256944444444445]
["ENSG00000111237","VPS29",12,110928902,110939922,-1,"protein_coding",51699,"VPS29",0.934744447933042,-0.696582918,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.3e-10,"d":"1.30E-10"},"rs4766578;rs11066320;rs570920196",37]
["ENSG00000151164","RAD9B",12,110939460,110969891,1,"protein_coding",144715,"RAD9B",{"v":3.62698610369545e-05,"d":"3.63E-05"},-0.76169697,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.3e-10,"d":"1.30E-10"},"rs4766578;rs11066320;rs570920196",37]
["ENSG00000196850","PPTC7",12,110969120,111021125,-1,"protein_coding",160760,"PPTC7",0.354852283261299,-2.603403438,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.3e-10,"d":"1.30E-10"},"rs4766578;rs11066320;rs570920196",37]
["ENSG00000204852","TCTN1",12,111051832,111087235,1,"protein_coding",79600,"TCTN1",{"v":1.86861398243824e-09,"d":"1.87E-09"},-0.456703465,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.3E-11,"d":"1.30E-11"},"rs4766578;rs11066320",37]
["ENSG00000186298","PPP1CC",12,111157485,111180744,-1,"protein_coding",5501,"PPP1CC",0.944905081326266,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.7e-12,"d":"6.70E-12"},"rs71079573;rs2241212:rs4766578;rs11066320;rs570920196:rs4766578;rs11066320:rs7973253:rs7973253;rs2241212:rs2241212",1.5256944444444445]
["ENSG00000111252","SH2B3",12,111843752,111889427,1,"protein_coding",10019,"SH2B3",0.00592218956138136,-0.243853728,3,11.21,9,{"v":1.97397E-5,"d":"1.97E-05"},{"v":3.10557e-07,"d":"3.11E-07"},"GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops",{"v":6.2e-12,"d":"6.20E-12"},"rs4766578;rs11066320;rs570920196;rs565349424;rs4766578:rs4766578",37]
["ENSG00000204842","ATXN2",12,111890018,112037480,-1,"protein_coding",6311,"ATXN2",0.999862271558356,-0.359942109,7,11.21,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":6.2e-12,"d":"6.20E-12"},"rs4766578;rs11066320;rs570920196:rs565349424:rs4766578",37]
["ENSG00000089234","BRAP",12,112079950,112123790,-1,"protein_coding",8315,"BRAP",0.0157033106581831,-0.900035073,3,8.201,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.2e-12,"d":"6.20E-12"},"rs4766578;rs11066320;rs570920196;rs565349424;rs570920196:rs565349424:rs4766578:rs4766578",37]
["ENSG00000111271","ACAD10",12,112123857,112194903,1,"protein_coding",80724,"ACAD10",{"v":4.01457480802773e-20,"d":"4.01E-20"},-0.311041181,4,4.336,3,{"v":5.5102e-05,"d":"5.51E-05"},0.0044547,"GTEx/v8/Heart_Left_Ventricle","+","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.2e-12,"d":"6.20E-12"},"rs565349424;rs4766578;rs11066320;rs570920196;rs570920196:rs565349424:rs4766578:rs4766578",37]
["ENSG00000257767","RP11-162P23.2",12,112191694,112229222,1,"protein_coding","NA","NA","NA","NA",2,4.336,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3e-10,"d":"1.30E-10"},"rs4766578;rs11066320;rs570920196;rs565349424;rs570920196:rs565349424:rs4766578",37]
["ENSG00000111275","ALDH2",12,112204691,112247782,1,"protein_coding",217,"ALDH2",{"v":1.73245219738394E-6,"d":"1.73E-06"},"NA",2,4.336,26,{"v":4.79083E-11,"d":"4.79E-11"},{"v":3.30709e-11,"d":"3.31E-11"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.2e-12,"d":"6.20E-12"},"rs4766578;rs11066320;rs570920196;rs565349424;rs570920196:rs4766578;rs11066320:rs565349424",37]
["ENSG00000089022","MAPKAPK5",12,112279782,112334343,1,"protein_coding",8550,"MAPKAPK5",0.0234226025504899,"NA",1,1.811,16,{"v":9.35224e-05,"d":"9.35E-05"},{"v":9.23515E-17,"d":"9.24E-17"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":6.2e-12,"d":"6.20E-12"},"rs4766578;rs11066320;rs570920196;rs570920196:rs565349424:rs4766578",37]
["ENSG00000198270","TMEM116",12,112369086,112450970,-1,"protein_coding",89894,"TMEM116",{"v":1.14999091475817e-09,"d":"1.15E-09"},-0.6208399,0,0,13,{"v":7.39446e-09,"d":"7.39E-09"},{"v":9.62641e-46,"d":"9.63E-46"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":6.2e-12,"d":"6.20E-12"},"rs4766578;rs11066320;rs565349424;rs570920196;rs570920196:rs570920196",37]
["ENSG00000089248","ERP29",12,112451120,112461255,1,"protein_coding",10961,"ERP29",0.470649236214131,-0.618385075,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.3e-10,"d":"1.30E-10"},"rs4766578;rs11066320;rs570920196:rs570920196",37]
["ENSG00000111300","NAA25",12,112464500,112546826,-1,"protein_coding",80018,"NAA25",0.999989964284881,-1.156261746,4,10.51,3,{"v":8.79199e-07,"d":"8.79E-07"},0.000286623,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":8.5e-11,"d":"8.50E-11"},"rs4766578;rs11066320;rs570920196;rs565349424",37]
["ENSG00000135148","TRAFD1",12,112563305,112591407,1,"protein_coding",10906,"TRAFD1",{"v":1.82691525643369E-5,"d":"1.83E-05"},-1.376326544,1,6.415,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3E-11,"d":"1.30E-11"},"rs4766578;rs11066320;rs570920196;rs570920196:rs4766578;rs11066320:rs4766578;rs570920196:rs565349424",37]
["ENSG00000173064","HECTD4",12,112597992,112819896,-1,"protein_coding",283450,"HECTD4",0.99999999999996,"NA",5,6.415,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-10,"d":"2.60E-10"},"rs4766578;rs11066320;rs570920196;rs570920196:rs4766578",37]
["ENSG00000089009","RPL6",12,112842994,112856642,-1,"protein_coding",6128,"RPL6",0.98828827107104,0.026755082,1,0.396,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.9e-10,"d":"2.90E-10"},"rs4766578;rs11066320;rs570920196",37]
["ENSG00000179295","PTPN11",12,112856155,112947717,1,"protein_coding",5781,"PTPN11",0.999877230878678,-2.25304246,5,9.917,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.3e-10,"d":"1.30E-10"},"rs4766578;rs11066320;rs570920196",37]
["ENSG00000089169","RPH3A",12,113008184,113336686,1,"protein_coding",22895,"RPH3A",0.738603478065915,0.425291504,37,8.899,0,"NA","NA","NA","NA","No","NA",{"v":1.9e-09,"d":"1.90E-09"},"rs570920196;rs233716;rs2384049",37]
["ENSG00000089127","OAS1",12,113344582,113369990,1,"protein_coding",4938,"OAS1",0.00123924128980461,-0.362759403,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesendoderm:hESC",{"v":1.9e-09,"d":"1.90E-09"},"rs4766578;rs11066320:rs2384049",37]
["ENSG00000111331","OAS3",12,113376157,113411054,1,"protein_coding",4940,"OAS3",{"v":1.82237568934062e-23,"d":"1.82E-23"},1.297253453,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.9e-09,"d":"1.90E-09"},"rs2384049",37]
["ENSG00000111335","OAS2",12,113416200,113449528,1,"protein_coding",4939,"OAS2",{"v":1.89091809637863E-14,"d":"1.89E-14"},-0.406420629,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.9e-09,"d":"1.90E-09"},"rs2384049",37]
["ENSG00000111344","RASAL1",12,113536624,113574044,-1,"protein_coding",8437,"RASAL1",{"v":4.85979006124582e-08,"d":"4.86E-08"},1.586043607,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4e-10,"d":"4.00E-10"},"rs4766578;rs11066320;rs570920196",37]
["ENSG00000089225","TBX5",12,114791736,114846247,-1,"protein_coding",6910,"TBX5",0.991878563864068,-0.562004347,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.9e-09,"d":"1.90E-09"},"rs2384049",37]
["ENSG00000089159","PXN",12,120648250,120703574,-1,"protein_coding",5829,"PXN",0.00656841085846847,-0.711885213,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.3e-08,"d":"1.30E-08"},"rs2244608;rs3213545:rs7970695",38]
["ENSG00000089163","SIRT4",12,120740119,120751052,1,"protein_coding",23409,"SIRT4",{"v":1.80676632025049E-7,"d":"1.81E-07"},-0.347424539,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":6.6e-09,"d":"6.60E-09"},"rs7970695:rs2244608;rs3213545",38]
["ENSG00000111775","COX6A1",12,120875893,120878545,1,"protein_coding",1337,"COX6A1",0.0609575623120839,0.176100304,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-12,"d":"3.20E-12"},"rs2244608:12:121386121_AG_A:rs2244608;rs3213545:rs7970695",38]
["ENSG00000111780","AL021546.6",12,120876001,120897809,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-12,"d":"3.20E-12"},"rs2244608:12:121386121_AG_A:rs2244608;rs3213545:rs7970695",38]
["ENSG00000170855","TRIAP1",12,120881764,120884215,-1,"protein_coding",51499,"TRIAP1",0.590216383617478,-0.444361269,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-12,"d":"3.20E-12"},"rs2244608:12:121386121_AG_A",38]
["ENSG00000257218","GATC",12,120884241,120899389,1,"protein_coding",283459,"GATC",{"v":7.79020409773576e-05,"d":"7.79E-05"},1.064180063,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-12,"d":"3.20E-12"},"rs2244608:12:121386121_AG_A",38]
["ENSG00000111786","SRSF9",12,120899471,120907596,-1,"protein_coding",8683,"SRSF9",0.819638672376706,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-12,"d":"2.20E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792",38]
["ENSG00000088986","DYNLL1",12,120907653,120936296,1,"protein_coding",8655,"DYNLL1",0.696580483081237,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-12,"d":"2.20E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792",38]
["ENSG00000110871","COQ5",12,120941077,120972237,-1,"protein_coding",84274,"COQ5",{"v":7.95018460631921e-05,"d":"7.95E-05"},0.02662786,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.6e-09,"d":"6.60E-09"},"rs7970695:rs2244608;rs3213545:rs3213545",38]
["ENSG00000022840","RNF10",12,120971283,121015397,1,"protein_coding",9921,"RNF10",0.502963048424231,0.037115157,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.6e-09,"d":"6.60E-09"},"rs7970695:rs2244608;rs3213545:rs3213545",38]
["ENSG00000167272","POP5",12,121016567,121019201,-1,"protein_coding",51367,"POP5",{"v":1.28002317887135E-5,"d":"1.28E-05"},-0.243976841,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.9E-12,"d":"1.90E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792:rs7970695:rs2244608;rs3213545:rs3213545:12:121386121_AG_A:rs11433243",38]
["ENSG00000157782","CABP1",12,121078355,121105127,1,"protein_coding",9478,"CABP1",0.994401234059643,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-12,"d":"2.20E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792",38]
["ENSG00000110917","MLEC",12,121124672,121139667,1,"protein_coding",9761,"MLEC",0.470920638317783,1.033373744,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":4e-13,"d":"4.00E-13"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792:rs7970695:rs2244608;rs3213545:rs2244608;12:121386121_AG_A:rs7970695;rs2244608;rs2393792:rs7970695;rs11433243:rs7970695;rs3213545:rs3213545:12:121386121_AG_A:rs11433243",38]
["ENSG00000175970","UNC119B",12,121148238,121161443,1,"protein_coding",84747,"UNC119B",0.677325341021738,0.550413245,0,0,5,{"v":2.45816e-05,"d":"2.46E-05"},0.000626415,"GTEx/v8/Adipose_Subcutaneous","+","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":4e-13,"d":"4.00E-13"},"rs2244608;12:121386121_AG_A;rs7970695;rs11433243;rs2393792;rs7970695:rs2244608;rs3213545:rs3213545:rs2244608:rs7970695;rs2393792:rs2393792:rs2244608;12:121386121_AG_A:rs7970695;rs2393792:rs7970695;rs11433243:rs7970695;rs2244608:rs7970695;rs3213545:12:121386121_AG_A:rs11433243",38]
["ENSG00000157837","SPPL3",12,121200313,121342174,-1,"protein_coding",121665,"SPPL3",0.907785634336426,0.151809144,0,0,37,{"v":2.12304e-07,"d":"2.12E-07"},{"v":3.87548e-20,"d":"3.88E-20"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","No","NA",{"v":5e-13,"d":"5.00E-13"},"rs2244608;rs7970695;rs11433243;rs2393792;12:121386121_AG_A;rs3213545",38]
["ENSG00000272214","AC079602.1",12,121407641,121410095,-1,"protein_coding","NA","NA","NA","NA",24,23.4,0,"NA","NA","NA","NA","No","NA",{"v":5e-13,"d":"5.00E-13"},"rs2244608;rs7970695;rs11433243;rs2393792;12:121386121_AG_A;rs3213545",38]
["ENSG00000135100","HNF1A",12,121416346,121440315,1,"protein_coding",6927,"HNF1A",0.969659467322862,-0.628781489,51,23.4,0,"NA","NA","NA","NA","No","NA",{"v":4e-13,"d":"4.00E-13"},"rs2244608;12:121386121_AG_A;rs7970695;rs11433243;rs2393792;rs3213545",38]
["ENSG00000157895","C12orf43",12,121440225,121454305,-1,"protein_coding",64897,"C12orf43",{"v":2.5600625299979e-07,"d":"2.56E-07"},0.963740862,28,22.3,63,{"v":5.40914e-19,"d":"5.41E-19"},{"v":4.17435e-40,"d":"4.17E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","No","NA",{"v":4e-13,"d":"4.00E-13"},"rs2244608;rs3213545;rs7970695;rs11433243;rs2393792;12:121386121_AG_A",38]
["ENSG00000135114","OASL",12,121458095,121477045,-1,"protein_coding",8638,"OASL",{"v":5.07293522290638e-12,"d":"5.07E-12"},0.332934746,9,8.319,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":6.6e-09,"d":"6.60E-09"},"rs2244608;rs3213545;rs7970695;rs7970695:rs2244608",38]
["ENSG00000089041","P2RX7",12,121570622,121623876,1,"protein_coding",5027,"P2RX7",{"v":3.78969928544417e-06,"d":"3.79E-06"},0.326948751,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.7e-08,"d":"4.70E-08"},"rs3213545",38]
["ENSG00000135124","P2RX4",12,121647660,121671909,1,"protein_coding",5025,"P2RX4",{"v":2.36800653754896e-09,"d":"2.37E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1.9E-12,"d":"1.90E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs11433243:rs3213545:rs7970695:rs2244608;rs3213545",38]
["ENSG00000110931","CAMKK2",12,121675497,121736111,-1,"protein_coding",10645,"CAMKK2",0.503475917086193,0.336425978,0,0,4,2.04434E-4,0.0246551,"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":9e-12,"d":"9.00E-12"},"rs2244608",38]
["ENSG00000089094","KDM2B",12,121866900,122018920,-1,"protein_coding",84678,"KDM2B",0.999785914187162,-0.426754489,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":4.7e-08,"d":"4.70E-08"},"rs3213545",38]
["ENSG00000139714","MORN3",12,122089024,122110537,-1,"protein_coding",283385,"MORN3",{"v":1.82555353991208e-06,"d":"1.83E-06"},1.089669662,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-12,"d":"2.20E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792",38]
["ENSG00000139725","RHOF",12,122215664,122241309,-1,"protein_coding",54509,"RHOF",0.00520736033592633,-0.238094128,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-12,"d":"2.20E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792",38]
["ENSG00000139718","SETD1B",12,122242086,122270562,1,"protein_coding",23067,"SETD1B",0.0224563158915498,-1.50972803,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.2e-12,"d":"2.20E-12"},"rs2244608:rs7970695;rs11433243;rs2393792:rs2393792",38]
["ENSG00000119242","CCDC92",12,124403207,124457378,-1,"protein_coding",80212,"CCDC92",0.368849605751602,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":2.8e-10,"d":"2.80E-10"},"rs865716",39]
["ENSG00000179195","ZNF664",12,124456392,124499986,1,"protein_coding",144348,"ZNF664",1.6267937964256E-3,-0.308462098,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":2.8e-10,"d":"2.80E-10"},"rs865716",39]
["ENSG00000178882","FAM101A",12,124457788,124800570,1,"protein_coding",144347,"FAM101A",0.212634236356269,0.253239307,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90",{"v":2.8e-10,"d":"2.80E-10"},"rs865716",39]
["ENSG00000073060","SCARB1",12,125261402,125367214,-1,"protein_coding",949,"SCARB1",0.0772244034409674,"NA",20,8.799,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.8e-10,"d":"2.80E-10"},"rs865716",39]
["ENSG00000150991","UBC",12,125396150,125401914,-1,"protein_coding",7316,"UBC",0.704156666525431,2.942576815,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_organ_oneway:Adult_Cortex",{"v":2.8e-10,"d":"2.80E-10"},"rs865716",39]
["ENSG00000139364","TMEM132B",12,125671382,126146917,1,"protein_coding",114795,"TMEM132B",0.455834501099099,1.571880434,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":1.8E-7,"d":"1.80E-07"},"rs865716",39]
["ENSG00000186009","ATP4B",13,114303119,114312501,-1,"protein_coding",496,"ATP4B",{"v":1.84084732787283e-05,"d":"1.84E-05"},-0.325434206,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-10,"d":"8.80E-10"},"rs6602911",40]
["ENSG00000184497","TMEM255B",13,114462216,114514926,1,"protein_coding",348013,"TMEM255B",{"v":3.85360358148072e-10,"d":"3.85E-10"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-10,"d":"8.80E-10"},"rs6602911",40]
["ENSG00000183087","GAS6",13,114523522,114567046,-1,"protein_coding",2621,"GAS6",0.333438602414211,"NA",20,8.523,19,{"v":2.0962e-12,"d":"2.10E-12"},{"v":8.39817e-08,"d":"8.40E-08"},"GTEx/v8/Liver","-","No","NA",{"v":8.8e-10,"d":"8.80E-10"},"rs6602911",40]
["ENSG00000130177","CDC16",13,115000362,115038198,1,"protein_coding",8881,"CDC16",0.952255349904704,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-10,"d":"8.80E-10"},"rs6602911",40]
["ENSG00000198824","CHAMP1",13,115079988,115092796,1,"protein_coding",283489,"CHAMP1",0.985193951059278,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":8.8e-10,"d":"8.80E-10"},"rs6602911",40]
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["ENSG00000157456","CCNB2",15,59397277,59417244,1,"protein_coding",9133,"CCNB2",{"v":1.58542348538884e-06,"d":"1.59E-06"},-0.394770432,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.4e-114,"d":"3.40E-114"},"rs8192701:rs6494005:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs10162642;rs554369334:rs554369334:rs1077835;rs261341:rs17301746:rs261341:rs488490:rs1077835;rs488490;rs572410:rs572410:rs488490;rs572410:rs35138338:rs79787170:rs413458:rs35550770:rs35550770;rs34433629:rs56195705:rs34433629:rs117459981:rs72740828:rs11853431:rs185221561:rs12907378:rs445093:rs11071373:rs445093;rs1560389:rs1560389:rs77703135;rs59739041:rs59739041:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs75663614:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs723967:rs11853674;rs55696635:rs76898656:rs76898656;rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs13329672;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs261341;15:58719759_CT_C:15:58719759_CT_C",41]
["ENSG00000157483","MYO1E",15,59427113,59665099,-1,"protein_coding",4643,"MYO1E",0.0479778930717418,0.925227799,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-34,"d":"2.60E-34"},"rs28607776;rs55966152:rs55966152:rs117266250:rs28607776:rs10162642:rs35717353:rs149299515:rs10162642;rs554369334:rs554369334",41]
["ENSG00000268327","C15ORF31",15,59439899,59440054,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.4e-114,"d":"3.40E-114"},"rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs10162642;rs554369334:rs554369334:rs413458:rs35550770:rs35550770;rs34433629:rs56195705:rs34433629:rs117459981:rs72740828:rs11853431:rs185221561:rs12907378:rs445093:rs11071373:rs445093;rs1560389:rs1560389:rs77703135;rs59739041:rs59739041:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs75663614:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs723967:rs11853674;rs55696635:rs76898656:rs76898656;rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs13329672;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs8192701:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs1077835;rs261341:rs17301746:rs261341:rs488490:rs1077835;rs488490;rs572410:rs572410:rs488490;rs572410:rs35138338:rs79787170",41]
["ENSG00000171989","LDHAL6B",15,59499042,59500705,1,"protein_coding",92483,"LDHAL6B",{"v":7.95326404010906e-07,"d":"7.95E-07"},1.80708977,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":3.4e-114,"d":"3.40E-114"},"rs72740828:rs11853431:rs445093:rs12907378:rs11071373:rs445093;rs1560389:rs1560389:rs77703135;rs59739041:rs59739041:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs10162642;rs554369334:rs554369334",41]
["ENSG00000157470","FAM81A",15,59664892,59815748,1,"protein_coding",145773,"FAM81A",0.487072320130673,-0.479273207,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-34,"d":"2.60E-34"},"rs28607776;rs55966152:rs55966152:rs117266250:rs28607776:rs10162642:rs35717353:rs149299515:rs10162642;rs554369334:rs554369334",41]
["ENSG00000140297","GCNT3",15,59887074,59932438,1,"protein_coding",9245,"GCNT3",{"v":4.04466927083348e-09,"d":"4.04E-09"},0.663107477,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-114,"d":"3.40E-114"},"rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs10162642;rs554369334:rs554369334:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs261290;rs1601935:rs723967:rs11853674;rs55696635:rs76898656:rs76898656;rs75127556:rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs13329672;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs72740828:rs11853431:rs445093:rs12907378:rs11071373:rs445093;rs1560389:rs1560389:rs77703135;rs59739041:rs59739041:rs147468898:rs145347194:rs200743386:rs4775039:rs10152355:rs1601935:rs117901517:rs8192701:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs1077835;rs261341:rs17301746:rs261341:rs488490:rs1077835;rs488490;rs572410:rs572410:rs488490;rs572410:rs35138338:rs79787170:rs413458:rs35550770:rs35550770;rs34433629:rs56195705:rs34433629:rs117459981:rs185221561",41]
["ENSG00000140307","GTF2A2",15,59930261,59949740,-1,"protein_coding",2958,"GTF2A2",0.386341515138839,0.898900449,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.4e-114,"d":"3.40E-114"},"rs72740828:rs11853431:rs445093:rs12907378:rs11071373:rs445093;rs1560389:rs1560389:rs77703135;rs59739041:rs59739041:rs147468898:rs145347194:rs200743386:rs75127556:rs4775039:rs10152355:rs1601933:rs261290;rs1601935:rs1601935:rs8042174:rs261290:rs723967;rs1601933:rs117901517:rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs261290;rs576650681:15:58682029_TGAA_T:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs75663614:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs723967:rs11853674;rs55696635:rs76898656:rs76898656;rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs13329672;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs28607776:rs10162642:rs149299515:rs10162642;rs554369334:rs554369334:rs413458:rs35550770:rs35550770;rs34433629:rs56195705:rs34433629:rs117459981:rs185221561",41]
["ENSG00000182718","ANXA2",15,60639333,60695082,-1,"protein_coding",302,"ANXA2",0.00984346288196249,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.9e-111,"d":"5.90E-111"},"rs117266250:rs35717353:rs55966152:rs28607776;rs55966152:rs28607776:rs10162642:rs149299515:rs10162642;rs554369334:rs554369334:rs413458:rs35550770:rs35550770;rs34433629:rs56195705:rs34433629:rs117459981:rs72740828:rs11853431:rs185221561:rs12907378:rs261290:rs261290;rs576650681:15:58682029_TGAA_T:rs1601933:rs576650681:rs11853674:rs34718390:15:58682029_TGAA_T;rs17240832:rs12708454:15:58682029_TGAA_T;rs12916206;rs17240832:rs723967;rs12438999:rs8042174:rs75663614:rs723967;rs1601933:rs723967;rs1601933;rs11071380:rs118078695:rs17240832:rs261290;rs1601935:rs723967:rs11853674;rs55696635:rs76898656:rs76898656;rs75127556:rs75127556:rs13329672;rs12708454:rs723967;rs12438999;rs11071380:rs11853674;rs13329672;rs55696635:rs34718390;rs62000866:rs55696635:rs13329672:rs13329672;rs55696635;rs11858279:rs62000866:rs12438999:rs723967;rs11858279:rs35300429:rs402465:rs55696635;rs11858279;rs62000869:rs12916206:rs62000869:rs12438999;rs11071380:rs77703135:rs11071380:rs11858279;rs62000869:rs402465;rs12916206:rs34727257:rs55696635;rs11858279:rs11858279:rs8026082:rs792902:rs515081:rs375372:rs6494005:rs261341;15:58719759_CT_C:15:58719759_CT_C:rs8192701:rs1077835;rs488490:rs1077835:rs11632618:rs1077835;rs261341;15:58719759_CT_C:rs17269250:rs72740877:rs1077835;rs261341:rs17301746:rs261341:rs488490:rs1077835;rs488490;rs572410:rs572410:rs488490;rs572410:rs35138338:rs79787170",41]
["ENSG00000159387","IRX6",16,55357672,55364672,1,"protein_coding",79190,"IRX6",{"v":2.81616051778102e-08,"d":"2.82E-08"},0.438476122,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":6.9e-08,"d":"6.90E-08"},"rs77188937",42]
["ENSG00000087253","LPCAT2",16,55542910,55620582,1,"protein_coding",54947,"LPCAT2",{"v":1.12519142457894e-06,"d":"1.13E-06"},1.042935368,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":2.3e-46,"d":"2.30E-46"},"rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",42]
["ENSG00000159398","CES5A",16,55880066,55989943,-1,"protein_coding",221223,"CES5A",{"v":5.95161189606759e-19,"d":"5.95E-19"},-0.208198829,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.9e-08,"d":"6.90E-08"},"rs77188937",42]
["ENSG00000159461","AMFR",16,56395364,56459450,-1,"protein_coding",267,"AMFR",0.00142575921262617,-0.148588909,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs1968493:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",42]
["ENSG00000167005","NUDT21",16,56463045,56486111,-1,"protein_coding",11051,"NUDT21",0.947296445770822,-0.951045808,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000087263","OGFOD1",16,56485402,56513012,1,"protein_coding",55239,"OGFOD1",{"v":1.29448940600909E-8,"d":"1.29E-08"},1.038879494,0,0,2,1.05209E-4,{"v":2.89269e-09,"d":"2.89E-09"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs59515242;rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000125124","BBS2",16,56500748,56554195,-1,"protein_coding",583,"BBS2",{"v":1.8525443177165E-10,"d":"1.85E-10"},0.988168918,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":7e-08,"d":"7.00E-08"},"rs77188937",42]
["ENSG00000102891","MT4",16,56598961,56602869,1,"protein_coding",84560,"MT4",0.0079945846958122,0.168441799,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs1968493:rs149137006:rs59515242:rs9921780:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",42]
["ENSG00000087250","MT3",16,56622986,56625000,1,"protein_coding",4504,"MT3",0.254133469605707,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs1968493:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs59515242:rs9921780",42]
["ENSG00000125148","MT2A",16,56642111,56643409,1,"protein_coding",4502,"MT2A",0.0538691874978182,-0.424007583,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000169715","MT1E",16,56659387,56661024,1,"protein_coding",4493,"MT1E",0.659212996447356,-0.089953071,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000268317","AC026461.1",16,56662971,56666150,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000205364","MT1M",16,56666145,56667898,1,"protein_coding",4499,"MT1M",{"v":9.83543934507332e-05,"d":"9.84E-05"},-0.29422965,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000205362","MT1A",16,56672578,56673999,1,"protein_coding",4489,"MT1A",0.0077761859390121,0.386134236,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780",42]
["ENSG00000169688","MT1B",16,56685811,56687116,1,"protein_coding",4490,"MT1B",0.248269442186515,0.35296703,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000198417","MT1F",16,56691606,56694610,1,"protein_coding",4494,"MT1F",0.0538496988016702,-0.344970169,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000125144","MT1G",16,56700643,56701977,-1,"protein_coding",4495,"MT1G",0.00811948407601034,0.102812001,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000205358","MT1H",16,56703726,56705041,1,"protein_coding",4496,"MT1H",0.0548412149416522,-0.294410812,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000187193","MT1X",16,56716336,56718108,1,"protein_coding",4501,"MT1X",0.0496111915968201,0.296377401,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs59515242:rs9921780:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000102900","NUP93",16,56764017,56878797,1,"protein_coding",9688,"NUP93",4.86804388235231E-3,"NA",31,21.8,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937;rs77188937:rs149137006:rs59515242:rs9921780:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs1968493:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000070915","SLC12A3",16,56899119,56949762,1,"protein_coding",6559,"SLC12A3",{"v":5.54410952233344e-18,"d":"5.54E-18"},1.058293826,71,15.56,21,{"v":2.23815e-05,"d":"2.24E-05"},0.0195847,"GTEx/v8/Pancreas","-","Yes","Aorta:Left_Ventricle:Liver:Pancreas:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937;rs1968493;rs149137006;rs59515242;rs9921780;rs755671262;rs77188937:rs149137006:rs59515242:rs9921780:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs118146573:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000051108","HERPUD1",16,56965960,56977798,1,"protein_coding",9709,"HERPUD1",0.82104286595303,-0.272869343,33,16.8,12,{"v":3.85117e-09,"d":"3.85E-09"},{"v":9.20685e-07,"d":"9.21E-07"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs149137006;rs755671262;rs193695;rs3764261;rs12448528;rs6499863;rs12923459;rs9921780;rs9921780:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs77188937:rs1968493:rs59515242:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000087237","CETP",16,56995762,57017757,1,"protein_coding",1071,"CETP",{"v":5.18056762742226e-12,"d":"5.18E-12"},0.043908821,77,23.5,28,{"v":2.31346E-8,"d":"2.31E-08"},{"v":7.55584e-05,"d":"7.56E-05"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs6499863;rs12923459;rs3764261;rs28888131;rs12720918;rs4783961;rs3816117;rs1864163;16:56997902_TTTTA_T;rs9929488;rs289713;rs118146573;rs11076174;rs11076176;rs289716;rs56208677;rs117427818;rs1968905;rs1800777;rs77188937:rs1968493:rs149137006:rs59515242:rs9921780:rs755671262:rs1864163;rs289713:rs118146573:rs3816117:rs3764261:rs9929488:rs289713:rs11076174:rs11076176:rs289716:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000140853","NLRC5",16,57023397,57117443,1,"protein_coding",84166,"NLRC5",{"v":6.71793792873124e-05,"d":"6.72E-05"},0.253521756,7,23.5,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-46,"d":"2.30E-46"},"rs117427818;rs1800777;rs289716;rs1968905;rs77188937:rs1968493:rs149137006:rs59515242:rs9921780:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488",42]
["ENSG00000140848","CPNE2",16,57126449,57181878,1,"protein_coding",221184,"CPNE2",0.544003069972159,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":2.1E-45,"d":"2.10E-45"},"rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076174:rs11076176:rs289716:rs77188937:rs1968493",42]
["ENSG00000172775","FAM192A",16,57186378,57220028,-1,"protein_coding",80011,"FAM192A",0.944099351189242,-0.529181943,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076174:rs11076176:rs289716:rs77188937:rs1968493:rs28888131:rs12720918:rs4783961:rs1864163:16:56997902_TTTTA_T:rs1864163;rs289713;rs9929488:rs59515242:rs9921780:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000159579","RSPRY1",16,57220049,57274387,1,"protein_coding",89970,"RSPRY1",0.999778005187676,-0.337763107,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.3e-46,"d":"2.30E-46"},"rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs1864163;rs289713:rs118146573:rs3816117:rs9929488:rs289713:rs11076174:rs11076176:rs289716:rs77188937:rs1968493:rs28888131:rs12720918:rs4783961:rs1864163:16:56997902_TTTTA_T:rs1864163;rs289713;rs9929488:rs59515242:rs9921780:rs56208677:rs117427818:rs1968905:rs117427818;rs1800777:rs1800777",42]
["ENSG00000102931","ARL2BP",16,57279010,57287516,1,"protein_coding",23568,"ARL2BP",0.000774155836962192,-0.164113324,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":2.3e-46,"d":"2.30E-46"},"rs77188937:rs1968493:rs149137006:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs59515242:rs9921780",42]
["ENSG00000102934","PLLP",16,57290004,57318599,-1,"protein_coding",51090,"PLLP",0.519581851885049,-0.311360157,0,0,3,{"v":2.83902e-05,"d":"2.84E-05"},{"v":2.34718e-05,"d":"2.35E-05"},"GTEx/v8/Liver","+","No","NA",{"v":9e-06,"d":"9.00E-06"},"rs149137006",42]
["ENSG00000102962","CCL22",16,57392684,57400102,1,"protein_coding",6367,"CCL22",0.279053454796883,1.694728431,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2.3e-46,"d":"2.30E-46"},"rs149137006:rs59515242:rs9921780:rs755671262:rs193695:rs3764261:rs12448528:rs6499863:rs12923459:rs28888131:rs12720918:rs4783961:rs3816117:rs1864163:16:56997902_TTTTA_T:rs9929488:rs1864163;rs289713:rs1864163;rs289713;rs9929488:rs77188937",42]
["ENSG00000006210","CX3CL1",16,57406370,57418960,1,"protein_coding",6376,"CX3CL1",0.963378216670433,0.27305282,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":5.1e-11,"d":"5.10E-11"},"rs77188937:rs1968493",42]
["ENSG00000102970","CCL17",16,57438679,57449974,1,"protein_coding",6361,"CCL17",0.0771247220885551,-0.1798114,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":5.1e-11,"d":"5.10E-11"},"rs77188937:rs1968493",42]
["ENSG00000103023","PRSS54",16,58313901,58328951,-1,"protein_coding",221191,"PRSS54",{"v":4.49967790564216e-05,"d":"4.50E-05"},0.526428905,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.5E-6,"d":"1.50E-06"},"rs77188937",42]
["ENSG00000181938","GINS3",16,58328984,58440048,1,"protein_coding",64785,"GINS3",0.236040219115464,0.283885897,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.5E-6,"d":"1.50E-06"},"rs77188937",42]
["ENSG00000103061","SLC7A6OS",16,68318406,68344849,-1,"protein_coding",84138,"SLC7A6OS",0.807327025070433,-1.885761498,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.3E-7,"d":"1.30E-07"},"rs76116020",43]
["ENSG00000132600","PRMT7",16,68344877,68392466,1,"protein_coding",54496,"PRMT7",{"v":8.30563679212495e-09,"d":"8.31E-09"},-0.873098608,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.3E-7,"d":"1.30E-07"},"rs76116020",43]
["ENSG00000103056","SMPD3",16,68392231,68482591,-1,"protein_coding",55512,"SMPD3",0.659196149583207,-0.537754418,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.3E-7,"d":"1.30E-07"},"rs76116020",43]
["ENSG00000184939","ZFP90",16,68563993,68609975,1,"protein_coding",146198,"ZFP90",0.00886192807104427,0.919738049,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Mesenchymal_Stem_Cell",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000062038","CDH3",16,68670092,68756519,1,"protein_coding",1001,"CDH3",{"v":1.8060327648012e-08,"d":"1.81E-08"},-0.571174777,1,3.007,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000039068","CDH1",16,68771128,68869451,1,"protein_coding",999,"CDH1",0.338547688109087,-0.027504257,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-7,"d":"1.30E-07"},"rs76116020",43]
["ENSG00000103047","TANGO6",16,68877507,69119083,1,"protein_coding",79613,"TANGO6",{"v":9.71153123642061e-09,"d":"9.71E-09"},-0.883785309,1,1.711,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000103044","HAS3",16,69139467,69152622,1,"protein_coding",3038,"HAS3",0.26938711218293,-0.838005778,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000168802","CHTF8",16,69151913,69166487,-1,"protein_coding",54921,"CHTF8",0.275816998725164,-0.491897054,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000263203","CHTF8",16,69152757,69154331,-1,"protein_coding",54921,"CHTF8","NA",-0.491897054,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000141076","CIRH1A",16,69165194,69265033,1,"protein_coding",84916,"CIRH1A",0.0940277046265138,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000168807","SNTB2",16,69221032,69342955,1,"protein_coding",6645,"SNTB2",0.036218317626175,-1.417098756,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000260914","RP11-343C2.11",16,69333585,69354614,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell:hESC",{"v":1.3E-7,"d":"1.30E-07"},"rs76116020",43]
["ENSG00000132612","VPS4A",16,69345259,69358949,1,"protein_coding",27183,"VPS4A","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell:hESC",{"v":1.3E-7,"d":"1.30E-07"},"rs76116020",43]
["ENSG00000213380","COG8",16,69354043,69373570,-1,"protein_coding",84342,"COG8",{"v":1.87304071695129e-05,"d":"1.87E-05"},-0.173605021,1,0.13,0,"NA","NA","NA","NA","No","NA",{"v":3.4E-8,"d":"3.40E-08"},"rs76116020",43]
["ENSG00000272617","RP11-343C2.12",16,69362547,69368774,-1,"protein_coding",84342,"COG8","NA","NA",1,0.13,0,"NA","NA","NA","NA","No","NA",{"v":3.4E-8,"d":"3.40E-08"},"rs76116020",43]
["ENSG00000260371","RP11-343C2.9",16,69368994,69390209,-1,"protein_coding","NA","NA","NA","NA",2,9.287,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000259900","RP11-343C2.7",16,69369179,69385633,-1,"protein_coding","NA","NA","NA","NA",2,9.287,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000132603","NIP7",16,69373333,69377014,1,"protein_coding",51388,"NIP7",0.603152382697747,1.129236796,2,9.287,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000157315","TMED6",16,69377151,69385712,-1,"protein_coding",146456,"TMED6",0.000563599382674353,-0.289729355,2,9.287,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000132604","TERF2",16,69389464,69442474,-1,"protein_coding",7014,"TERF2",0.927472177448586,-0.576801065,1,9.287,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000102908","NFAT5",16,69598997,69738569,1,"protein_coding",10725,"NFAT5",0.999990941723713,-0.85202623,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000181019","NQO1",16,69740899,69760854,-1,"protein_coding",1728,"NQO1",{"v":4.52404699215664e-11,"d":"4.52E-11"},-0.846833583,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000141101","NOB1",16,69775770,69788843,-1,"protein_coding",28987,"NOB1",{"v":8.61136358207129e-08,"d":"8.61E-08"},-0.798435745,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000198373","WWP2",16,69796209,69975644,1,"protein_coding",11060,"WWP2",0.977902374453959,0.163310833,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.6e-08,"d":"2.60E-08"},"rs76116020",43]
["ENSG00000108379","WNT3",17,44839872,44910520,-1,"protein_coding",7473,"WNT3",0.946108101336536,-0.191110949,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.6e-07,"d":"4.60E-07"},"rs4561509",44]
["ENSG00000158955","WNT9B",17,44910567,44964096,1,"protein_coding",7484,"WNT9B",0.0516168107144711,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":4.6e-07,"d":"4.60E-07"},"rs4561509",44]
["ENSG00000179673","RPRML",17,45055523,45056614,-1,"protein_coding",388394,"RPRML",0.421294822682809,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000004897","CDC27",17,45195069,45266788,-1,"protein_coding",996,"CDC27",0.486673202422918,-0.787143256,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000198336","MYL4",17,45277812,45301045,1,"protein_coding",4635,"MYL4",0.000175624794353708,-0.333740158,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000259207","ITGB3",17,45331212,45421658,1,"protein_coding",3690,"ITGB3",0.141699544644917,-0.21470934,1,1.258,3,2.15295E-4,{"v":2.16068e-14,"d":"2.16E-14"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000259753","ITGB3",17,45331263,45421658,1,"protein_coding",3690,"ITGB3","NA",-0.21470934,1,1.258,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000178852","EFCAB13",17,45400656,45518678,1,"protein_coding",124989,"EFCAB13",{"v":8.2199210022743e-19,"d":"8.22E-19"},-0.190444586,29,12.57,170,{"v":5.94707e-38,"d":"5.95E-38"},{"v":2.74933e-40,"d":"2.75E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000141279","NPEPPS",17,45600308,45700642,1,"protein_coding",9520,"NPEPPS",0.999905920388338,-0.210177495,87,18.74,170,{"v":2.90589e-11,"d":"2.91E-11"},{"v":9.82507e-09,"d":"9.83E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","EP_links_oneway:Promoter_anchored_loops",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000108424","KPNB1",17,45726842,45762871,1,"protein_coding",3837,"KPNB1",0.999994327501246,-0.517927071,40,21.3,2,{"v":7.66924e-05,"d":"7.67E-05"},0.0305572,"GTEx/v8/Artery_Tibial:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000198933","TBKBP1",17,45771447,45789416,1,"protein_coding",9755,"TBKBP1",0.0383777655190971,-1.546187862,25,21.3,170,{"v":2.31691e-79,"d":"2.32E-79"},{"v":5.36782E-67,"d":"5.37E-67"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000073861","TBX21",17,45810610,45823485,1,"protein_coding",30009,"TBX21",0.963242650804377,0.083150474,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000006025","OSBPL7",17,45884738,45899200,-1,"protein_coding",114881,"OSBPL7",0.181605380199765,0.183707295,0,0,43,{"v":5.05125e-06,"d":"5.05E-06"},{"v":1.39226e-09,"d":"1.39E-09"},"GTEx/v8/Artery_Aorta","+","Yes","EP_correlation_cell_type_oneway",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000159111","MRPL10",17,45900638,45908900,-1,"protein_coding",124995,"MRPL10",0.288891351405341,1.414394125,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.7E-6,"d":"1.70E-06"},"rs4561509",44]
["ENSG00000141294","LRRC46",17,45908993,45915079,1,"protein_coding",90506,"LRRC46",0.000135433194771157,-0.757958927,0,0,1,{"v":4.7237e-05,"d":"4.72E-05"},{"v":1.3074e-07,"d":"1.31E-07"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops",{"v":1.7E-6,"d":"1.70E-06"},"rs4561509",44]
["ENSG00000141295","SCRN2",17,45915058,45918699,-1,"protein_coding",90507,"SCRN2",{"v":6.55878589036845e-07,"d":"6.56E-07"},-0.299714101,0,0,21,{"v":2.39749E-5,"d":"2.40E-05"},{"v":1.90223E-29,"d":"1.90E-29"},"GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","No","NA",{"v":9.6e-07,"d":"9.60E-07"},"rs4561509",44]
["ENSG00000189120","SP6",17,45922279,45933240,-1,"protein_coding",80320,"SP6",0.0229475656346052,-1.129577219,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.9e-08,"d":"2.90E-08"},"rs4561509",44]
["ENSG00000108439","PNPO",17,46018872,46025654,1,"protein_coding",55163,"PNPO",{"v":3.71896087830709e-05,"d":"3.72E-05"},0.179349996,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000167183","PRR15L",17,46029333,46035244,-1,"protein_coding",79170,"PRR15L",0.481246950810061,0.303263346,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000108465","CDK5RAP3",17,46045176,46059140,1,"protein_coding",80279,"CDK5RAP3",{"v":2.8653949299435e-12,"d":"2.87E-12"},0.440977845,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Trophoblast-like_Cell",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000120093","HOXB3",17,46626232,46682274,-1,"protein_coding",3213,"HOXB3",0.610993265044198,-1.020697429,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000108511","HOXB6",17,46671639,46682354,-1,"protein_coding",3216,"HOXB6",0.00958340713523565,-0.016604333,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000260027","HOXB7",17,46684594,46710934,-1,"protein_coding",3217,"HOXB7",0.00759639061323712,-0.376189201,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000120068","HOXB8",17,46688739,46692478,-1,"protein_coding",3218,"HOXB8",0.444768417534794,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000170689","HOXB9",17,46698518,46703839,-1,"protein_coding",3219,"HOXB9",0.101637476227325,0.72463007,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2e-07,"d":"2.00E-07"},"rs4561509",44]
["ENSG00000167080","B4GALNT2",17,47209822,47247351,1,"protein_coding",124872,"B4GALNT2",{"v":9.64033158743695e-07,"d":"9.64E-07"},-0.518246922,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.6e-06,"d":"1.60E-06"},"rs4561509",44]
["ENSG00000186665","C17orf58",17,65987217,65989765,-1,"protein_coding",284018,"C17orf58",0.0821564161266073,0.225875314,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":6.1e-07,"d":"6.10E-07"},"rs740516",45]
["ENSG00000196704","AMZ2",17,66243715,66253297,1,"protein_coding",51321,"AMZ2",{"v":1.54653236502662e-08,"d":"1.55E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000141337","ARSG",17,66255323,66418872,1,"protein_coding",22901,"ARSG",{"v":1.55401104160652e-05,"d":"1.55E-05"},-0.073146217,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000108932","SLC16A6",17,66263167,66287408,-1,"protein_coding",9120,"SLC16A6",0.205129420734742,0.544953981,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000070540","WIPI1",17,66417089,66453654,-1,"protein_coding",55062,"WIPI1",0.523500460994852,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000108946","PRKAR1A",17,66507921,66547460,1,"protein_coding",5573,"PRKAR1A",0.999223269468243,-0.526046164,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000108950","FAM20A",17,66531254,66597530,-1,"protein_coding",54757,"FAM20A",0.00250112243343209,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000269657","AC079210.1",17,66539369,66542970,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000141338","ABCA8",17,66863433,66951533,-1,"protein_coding",10351,"ABCA8",{"v":1.71937025604407e-33,"d":"1.72E-33"},-0.722805264,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000154258","ABCA9",17,66970629,67057205,-1,"protein_coding",10350,"ABCA9",{"v":1.27777342298461E-26,"d":"1.28E-26"},0.808506325,0,0,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000154262","ABCA6",17,67074843,67138029,-1,"protein_coding",23460,"ABCA6",{"v":1.83135791674863E-16,"d":"1.83E-16"},0.04887392,1,5.05,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000154263","ABCA10",17,67143355,67240987,-1,"protein_coding",10349,"ABCA10",{"v":1.20688643660446E-27,"d":"1.21E-27"},1.186945085,2,0.6,0,"NA","NA","NA","NA","Yes","Liver:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000153822","KCNJ16",17,68049570,68131749,1,"protein_coding",3773,"KCNJ16",{"v":5.41974671317498e-06,"d":"5.42E-06"},0.221443806,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000123700","KCNJ2",17,68164814,68176189,1,"protein_coding",3759,"KCNJ2",0.820229027644725,0.661521385,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000267893","AC007461.1",17,70036164,70036872,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.4E-8,"d":"2.40E-08"},"rs740516",45]
["ENSG00000206181","TCEB3B",18,44558943,44561988,-1,"protein_coding",51224,"TCEB3B",{"v":1.80367559188731E-8,"d":"1.80E-08"},-0.015254462,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":4.1e-13,"d":"4.10E-13"},"rs150342704;rs7238327:rs2000827:rs9964112:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796",47]
["ENSG00000267228","IER3IP1",18,44661027,44702652,-1,"protein_coding",51124,"IER3IP1","NA",-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.1E-12,"d":"1.10E-12"},"rs9947678:rs150342704;rs7238327:rs9964112:rs2000827:rs498209",47]
["ENSG00000134049","IER3IP1",18,44681413,44702745,-1,"protein_coding",51124,"IER3IP1",0.0184346889412637,-0.130293896,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.1E-12,"d":"1.10E-12"},"rs9947678:rs150342704;rs7238327:rs9964112:rs2000827:rs498209",47]
["ENSG00000215474","SKOR2",18,44746293,44775554,-1,"protein_coding",652991,"SKOR2",0.611171343025554,-0.166850887,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.1e-13,"d":"4.10E-13"},"rs9947678:rs150342704;rs7238327:rs9964112:rs2000827:rs498209:rs79204427:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796",47]
["ENSG00000184828","ZBTB7C",18,45553044,45937123,-1,"protein_coding",201501,"ZBTB7C",0.907221460237709,-0.062747095,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":6.8e-41,"d":"6.80E-41"},"rs113258273:rs12963212:rs6507928:rs61124986:rs62100587:rs7228085:rs9304381:rs12955369:rs9947684:rs374401823:rs61124986;rs62100627:rs9304381;rs1540037:rs62100587;rs61124986:rs118043171:rs73432460:rs62100627:rs7230869:rs4939888:rs62100587;rs1540036:rs1540037:rs1540036:rs11662691:rs6507942:rs34627148:rs150560851:rs7505352:rs6507942;rs8093891:rs75786906:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs12454370:rs62101776;rs12454370;rs8093891:rs950659;rs7238327:rs8093891:18:47211493_ACATC_A:rs2000827:rs58408217:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs7232836:rs6507945;rs12965067;rs7232836;rs112748087:rs147708674:rs80175721;rs79204427:rs9964112:rs3892138:rs7234216;rs2848986:rs7238327:rs147708674;18:47388060_TC_T:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:18:47280133_TACACACACACAC_T:rs7239952:rs9947678:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704;rs7238327:18:47388060_TC_T:rs150342704:rs188501176:rs10639158:rs498209:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796:rs79204427:rs536271135:rs79204427;rs536271135",47]
["ENSG00000134030","CTIF",18,46065417,46389588,1,"protein_coding",9811,"CTIF",0.982754580423637,-0.933481785,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2e-09,"d":"2.00E-09"},"rs75786906:rs138215167:rs113258273:rs12963212:rs6507928",1.9493055555555554]
["ENSG00000101665","SMAD7",18,46446223,46477081,-1,"protein_coding",4092,"SMAD7",0.975695730781462,-0.748267715,3,7.5,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.4e-11,"d":"7.40E-11"},"rs138215167;rs113258273:rs12963212:rs6507928:rs9953300:rs75786906",1.9493055555555554]
["ENSG00000141627","DYM",18,46570039,46987717,-1,"protein_coding",54808,"DYM",{"v":5.18111501130597e-09,"d":"5.18E-09"},-0.135200517,3,4.83,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2E-23,"d":"1.20E-23"},"rs75786906;rs113258273;rs12963212:rs113258273:rs138215167:18:47388060_TC_T:rs9964112:rs188501176:rs150342704;rs7238327:rs10639158:rs498209:rs75786906:rs6507928:rs9953300:rs80175721;rs79204427:rs2000827:rs9947678:rs7238327:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:rs7239952:rs58408217:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704",1.9493055555555554]
["ENSG00000177576","C18orf32",18,47008028,47013622,-1,"protein_coding",497661,"C18orf32",0.18275268888643,-0.238183839,24,11.01,36,{"v":2.18482e-06,"d":"2.18E-06"},{"v":7.11808e-09,"d":"7.12E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs12963212;rs6507928;rs113258273;rs73959582;rs150342704;rs7238327:rs9964112:rs498209:18:47388060_TC_T:rs75786906:rs113258273:rs12963212:rs6507928:18:47099100_TAA_T:rs12966382:rs1320700:rs138215167:rs62100587:rs9304381;rs1540037:rs73432460:rs62100627:rs9304381:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs950659;rs7238327:rs2000827:rs58408217:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7234216;rs2848986:rs7238327:rs80175721;rs79204427:rs147708674;18:47388060_TC_T:rs9947678:rs6507945;rs12965067;rs7232836;rs112748087:rs147708674:rs7232836:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:18:47280133_TACACACACACAC_T:rs7239952:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704:rs188501176:rs10639158:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796:rs536271135:rs79204427;rs536271135:rs113258273;rs12963212:rs80204526:rs12608026:rs61124986:rs7228085:rs12955369:rs9947684:rs374401823:rs61124986;rs62100627:rs62100587;rs61124986:rs118043171:rs62100587;rs1540036:rs1540037:rs1540036:rs11662691:rs150560851:rs7505352:rs543290276:18:47098703_TAAAA_T:rs11662596:rs140608411:rs77960347;rs80204526:rs77960347:rs4121823:rs79204427",1.9493055555555554]
["ENSG00000215472","RPL17-C18orf32",18,47008051,47017956,-1,"protein_coding",100526842,"RPL17-C18orf32",0.605942171595584,-0.340213428,27,11.01,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs12963212;rs6507928;rs113258273;rs150342704;rs7238327:rs9964112:rs498209:18:47388060_TC_T:rs75786906:rs113258273:rs12963212:rs6507928:18:47099100_TAA_T:rs12966382:rs1320700:rs138215167:rs62100587:rs9304381;rs1540037:rs73432460:rs62100627:rs9304381:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs950659;rs7238327:rs2000827:rs58408217:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7234216;rs2848986:rs7238327:rs80175721;rs79204427:rs147708674;18:47388060_TC_T:rs9947678:rs6507945;rs12965067;rs7232836;rs112748087:rs147708674:rs7232836:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:18:47280133_TACACACACACAC_T:rs7239952:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704:rs188501176:rs10639158:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796:rs536271135:rs79204427;rs536271135:rs113258273;rs12963212:rs80204526:rs12608026:rs61124986:rs7228085:rs12955369:rs9947684:rs374401823:rs61124986;rs62100627:rs62100587;rs61124986:rs118043171:rs62100587;rs1540036:rs1540037:rs1540036:rs11662691:rs150560851:rs7505352:rs543290276:18:47098703_TAAAA_T:rs11662596:rs140608411:rs77960347;rs80204526:rs77960347:rs4121823:rs79204427",1.9493055555555554]
["ENSG00000265681","RPL17",18,47014851,47018906,-1,"protein_coding",6139,"RPL17",0.494059426420399,0.186983574,23,11.01,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs12963212;rs6507928;rs113258273;rs150342704;rs7238327:rs9964112:rs498209:18:47388060_TC_T:rs75786906:rs113258273:rs12963212:rs6507928:18:47099100_TAA_T:rs12966382:rs1320700:rs138215167:rs62100587:rs9304381;rs1540037:rs73432460:rs62100627:rs9304381:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs950659;rs7238327:rs2000827:rs58408217:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7234216;rs2848986:rs7238327:rs80175721;rs79204427:rs147708674;18:47388060_TC_T:rs9947678:rs6507945;rs12965067;rs7232836;rs112748087:rs147708674:rs7232836:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:18:47280133_TACACACACACAC_T:rs7239952:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704:rs188501176:rs10639158:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796:rs536271135:rs79204427;rs536271135:rs113258273;rs12963212:rs80204526:rs12608026:rs61124986:rs7228085:rs12955369:rs9947684:rs374401823:rs61124986;rs62100627:rs62100587;rs61124986:rs118043171:rs62100587;rs1540036:rs1540037:rs1540036:rs11662691:rs150560851:rs7505352:rs543290276:18:47098703_TAAAA_T:rs11662596:rs140608411:rs77960347;rs80204526:rs77960347:rs4121823:rs79204427",1.9493055555555554]
["ENSG00000101670","LIPG",18,47087069,47119272,1,"protein_coding",9388,"LIPG",{"v":8.35570265503166e-05,"d":"8.36E-05"},-0.057562727,74,24.1,11,{"v":6.52812e-06,"d":"6.53E-06"},0.00061259,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs1320700;18:47099100_TAA_T;rs12966382;rs543290276;18:47098703_TAAAA_T;rs11662596;rs140608411;rs77960347;rs80204526;rs12608026;rs4121823;18:47126878_GC_G;rs1105654;rs10853582;rs150342704;rs7238327:rs498209:rs9964112:rs2000827:18:47388060_TC_T:rs12963212:rs113258273:rs34627148:rs6507942:rs75786906:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs62100587:rs9304381;rs1540037:rs73432460:rs62100627:rs9304381:rs7230869:rs4939888:rs950659;rs7238327:rs58408217:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs3892138:rs7234216;rs2848986:rs7238327:rs80175721;rs79204427:rs147708674;18:47388060_TC_T:rs12454370:rs62101776;rs12454370;rs8093891:rs8093891:18:47211493_ACATC_A:rs7232836:rs188501176:rs10639158:rs6507945;rs12965067;rs7232836;rs112748087:rs147708674:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:18:47280133_TACACACACACAC_T:rs7239952:rs9947678:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704:rs6507928",47]
["ENSG00000167315","ACAA2",18,47309869,47340330,-1,"protein_coding",10449,"ACAA2","NA","NA",32,16.22,29,{"v":3.29326e-08,"d":"3.29E-08"},{"v":6.07479e-14,"d":"6.07E-14"},"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs75786906;rs2000827;rs9964112;rs150342704;rs7238327;18:47388060_TC_T;rs188501176;rs10639158;rs498209;rs1787328;rs12963212:rs113258273:18:47099100_TAA_T:rs1320700:rs543290276:18:47098703_TAAAA_T:rs11662596:rs150342704;rs7238327:rs498209:rs9964112:rs12966382:rs34627148:rs6507942:rs75786906:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs6507928:rs80175721;rs79204427:rs2000827:18:47388060_TC_T:rs9947678:rs113258273;rs12963212:rs80204526:rs12608026:rs140608411:rs77960347;rs80204526:rs77960347:rs4121823:rs61124986:rs62100587:rs7228085:rs9304381:rs12955369:rs9947684:rs374401823:rs61124986;rs62100627:rs9304381;rs1540037:rs62100587;rs61124986:rs118043171:rs73432460:rs62100627:rs7230869:rs4939888:rs62100587;rs1540036:rs1540037:rs1540036:rs11662691:rs150560851:rs7505352:rs12454370:rs62101776;rs12454370;rs8093891:rs950659;rs7238327:rs8093891:18:47211493_ACATC_A:rs58408217:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs7232836:rs7238327:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:rs7239952:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704",47]
["ENSG00000266997","RP11-886H22.1",18,47322163,47363993,-1,"protein_coding","NA","NA","NA","NA",35,10.54,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs150342704;rs7238327;18:47388060_TC_T;rs9964112;rs188501176;rs10639158;rs498209;rs75786906;rs80175721;rs79204427;rs113258273:rs12963212:rs6507928:rs113258273;rs12963212:rs80204526:rs12608026:rs1320700:18:47099100_TAA_T:18:47388060_TC_T:rs9964112:rs188501176:rs150342704;rs7238327:rs10639158:rs498209:rs75786906:rs7238327:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs9947678;rs7239952:rs7239952:rs58408217:rs9947678:rs9947678;rs7239952:rs7234216:rs2848986:rs80175721;rs79204427:rs2000827:rs150342704:rs12966382:rs543290276:18:47098703_TAAAA_T:rs11662596:rs140608411:rs77960347;rs80204526:rs77960347:rs4121823:18:47126878_GC_G:rs1105654;rs10853582:rs10853582:rs28666039:18:47147111_TCCTCTCCCTCCTC_T:rs1105654:rs7229377:rs34802337:rs11663245:rs73959582:rs35311766:rs7235080:rs61124986;rs62100627:rs11662059:rs7230869:rs9304381:rs7229658:rs62100587:rs61124986:rs7228085:rs12955369:rs9947684:rs374401823:rs9304381;rs1540037:rs62100587;rs61124986:rs118043171:rs73432460:rs62100627:rs4939888:rs62100587;rs1540036:rs1540037:rs1540036:rs11662691:rs6507942:rs34627148:rs150560851:rs7505352:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs12454370:rs62101776;rs12454370;rs8093891:rs950659;rs7238327:rs8093891:18:47211493_ACATC_A:rs6507945:rs12965067:rs112748087:rs12965067;rs112748087:rs7232836:rs6507945;rs12965067;rs7232836;rs112748087:rs147708674:rs3892138:rs7234216;rs2848986:rs147708674",47]
["ENSG00000167306","MYO5B",18,47349183,47721463,-1,"protein_coding",4645,"MYO5B",{"v":5.4231747689238e-10,"d":"5.42E-10"},0.470845589,242,18.42,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.8e-55,"d":"3.80E-55"},"rs498209;18:47388060_TC_T;rs150342704;rs7238327;rs75786906;rs9964112;rs80175721;rs79204427;rs2000827;rs9947678;rs80187959;rs1787328;rs10641449;rs12962112;rs1790796;rs12963212:rs113258273:18:47099100_TAA_T:rs12966382:rs1320700:rs6507928:rs113258273;rs12963212:rs80204526:rs12608026:rs9947678:rs150342704;rs7238327:rs9964112:rs2000827:rs498209:rs79204427;rs536271135:rs536271135:rs543290276:18:47098703_TAAAA_T:rs11662596:rs140608411:rs77960347;rs80204526:rs77960347:rs4121823:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796:rs75786906:rs80175721;rs79204427:rs79204427:18:47388060_TC_T:rs188501176:rs10639158:rs7238327:18:47280133_TACACACACACAC_T:18:47280133_TACACACACACAC_T;rs7239952:rs7239952:rs58408217:rs9947678;rs7239952:rs7234216:rs2848986:rs150342704",47]
["ENSG00000172361","CCDC11",18,47753563,47792892,-1,"protein_coding",220136,"CCDC11",{"v":1.5987996365213e-13,"d":"1.60E-13"},-0.596742517,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.9e-47,"d":"9.90E-47"},"rs12963212:rs113258273:18:47099100_TAA_T:rs12966382:rs1320700:rs498209:18:47388060_TC_T:rs150342704;rs7238327:rs75786906:rs9964112:rs62100587:rs9304381;rs1540037:rs73432460:rs62100627:rs9304381:rs7230869:rs4939888:rs34627148:rs6507942:rs6507942;rs8093891:rs34627148;rs147708674;rs34532269:rs950659:rs34532269:rs62101776:rs80175721:rs2000827:rs536271135:rs79204427;rs536271135:rs6507928:rs113258273;rs12963212:rs80204526:rs12608026:rs80175721;rs79204427:rs9947678:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796",47]
["ENSG00000154832","CXXC1",18,47808713,47814674,-1,"protein_coding",30827,"CXXC1",0.99786210530366,-0.476982834,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-12,"d":"2.30E-12"},"rs150342704;rs7238327:rs9964112",47]
["ENSG00000154839","SKA1",18,47901365,47920543,1,"protein_coding",220134,"SKA1",{"v":1.32265949651803E-6,"d":"1.32E-06"},0.423231094,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":9.9e-47,"d":"9.90E-47"},"rs113258273:rs12963212:18:47099100_TAA_T:rs12966382:rs1320700:rs6507928:rs113258273;rs12963212:rs80204526:rs12608026:rs79204427;rs536271135:rs80175721;rs79204427:rs536271135:rs150342704;rs7238327:rs2000827:rs9964112:rs80187959:rs1787328:rs10641449:rs12962112:rs1790796:rs9947678:rs498209",47]
["ENSG00000130812","ANGPTL6",19,10203014,10213472,-1,"protein_coding",83854,"ANGPTL6",{"v":2.76981473339532E-8,"d":"2.77E-08"},-0.292124052,0,0,1,1.90516E-4,0.0147866,"GTEx/v8/Adipose_Subcutaneous","-","No","NA",{"v":1.2E-10,"d":"1.20E-10"},"rs73015030",48]
["ENSG00000105364","MRPL4",19,10362577,10370721,1,"protein_coding",51073,"MRPL4",{"v":1.13185886619774E-7,"d":"1.13E-07"},0.262339703,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.6E-7,"d":"1.60E-07"},"rs17850995",48]
["ENSG00000105371","ICAM4",19,10397643,10399198,1,"protein_coding",3386,"ICAM4",{"v":1.53444721877808e-05,"d":"1.53E-05"},-0.287199811,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":3.4e-09,"d":"3.40E-09"},"rs17850995:rs140493437",48]
["ENSG00000161847","RAVER1",19,10426888,10444316,-1,"protein_coding",125950,"RAVER1",0.982340267394972,-0.93631161,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-07,"d":"2.30E-07"},"rs12052200",48]
["ENSG00000076662","ICAM3",19,10444452,10450499,-1,"protein_coding",3385,"ICAM3",{"v":2.07707792396741e-22,"d":"2.08E-22"},-0.380120969,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.3e-07,"d":"2.30E-07"},"rs12052200",48]
["ENSG00000079999","KEAP1",19,10596796,10614417,-1,"protein_coding",9817,"KEAP1",0.251629057539983,-0.049345802,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.4e-09,"d":"3.40E-09"},"rs140493437:rs17850995",48]
["ENSG00000180739","S1PR5",19,10623623,10628607,-1,"protein_coding",53637,"S1PR5",0.0574132950803294,-0.598100848,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.6E-7,"d":"1.60E-07"},"rs17850995",48]
["ENSG00000130734","ATG4D",19,10654571,10664094,1,"protein_coding",84971,"ATG4D",0.000323903626106917,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6E-7,"d":"1.60E-07"},"rs17850995",48]
["ENSG00000129347","KRI1",19,10663761,10676713,-1,"protein_coding",65095,"KRI1",{"v":8.4034020734588E-9,"d":"8.40E-09"},-0.684287675,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6E-7,"d":"1.60E-07"},"rs17850995",48]
["ENSG00000129355","CDKN2D",19,10677138,10679735,-1,"protein_coding",1032,"CDKN2D",0.147286959437682,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.6E-7,"d":"1.60E-07"},"rs17850995",48]
["ENSG00000129354","AP1M2",19,10683347,10697991,-1,"protein_coding",10053,"AP1M2",0.00134595247967371,-0.043748277,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.6E-7,"d":"1.60E-07"},"rs17850995",48]
["ENSG00000129353","SLC44A2",19,10713133,10755235,1,"protein_coding",57153,"SLC44A2",0.0414645881648824,-0.378860929,1,0.101,5,{"v":2.77111E-5,"d":"2.77E-05"},0.000289454,"GTEx/v8/Artery_Tibial","+","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-28,"d":"3.20E-28"},"rs17850995;rs142158911;rs59716766",48]
["ENSG00000226104","AC011475.1",19,10751715,10752093,1,"protein_coding","NA","NA","NA","NA",1,0.101,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":2.3e-11,"d":"2.30E-11"},"rs17850995;rs17850995:rs140493437:rs17850995;rs73013159:rs12052200:rs56121005",48]
["ENSG00000129351","ILF3",19,10764937,10803093,1,"protein_coding",3609,"ILF3",0.999996830604967,-0.897292942,2,6.331,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":3.2e-09,"d":"3.20E-09"},"rs17850995",48]
["ENSG00000213339","QTRT1",19,10812106,10824113,1,"protein_coding",81890,"QTRT1",0.000223249642879381,-0.342791499,2,6.331,0,"NA","NA","NA","NA","No","NA",{"v":4.5e-09,"d":"4.50E-09"},"rs17850995;19:10818512_GT_G",48]
["ENSG00000079805","DNM2",19,10828755,10944164,1,"protein_coding",1785,"DNM2",0.999968599089655,-0.475523782,19,10.77,13,{"v":4.06798e-06,"d":"4.07E-06"},{"v":5.39957e-09,"d":"5.40E-09"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","No","NA",{"v":5e-11,"d":"5.00E-11"},"rs140493437;rs17850995;rs73013159",48]
["ENSG00000099203","TMED1",19,10943114,10946994,-1,"protein_coding",11018,"TMED1",0.000162416907640562,-0.379917355,10,10.77,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":2.3e-11,"d":"2.30E-11"},"rs17850995;rs73013159;rs140493437;rs17850995:rs56121005",48]
["ENSG00000214212","C19orf38",19,10947251,10980466,1,"protein_coding",255809,"C19orf38","NA",0.100777924,11,10.77,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Mesenchymal_Stem_Cell",{"v":2.3e-11,"d":"2.30E-11"},"rs17850995;rs73013159;rs140493437;rs17850995:rs56121005",48]
["ENSG00000142453","CARM1",19,10982189,11033453,1,"protein_coding",10498,"CARM1",0.999357708272541,"NA",2,0.761,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-50,"d":"1.80E-50"},"rs17850995;rs73013159:rs140493437:rs17850995:rs73013159:rs12052200:rs59716766:rs142158911;rs59716766:rs142158911",48]
["ENSG00000130733","YIPF2",19,11033444,11039357,-1,"protein_coding",78992,"YIPF2",1.09917458451604E-3,"NA",1,0.761,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-50,"d":"1.80E-50"},"rs17850995;rs12052200:rs737337:rs56048141:rs56121005:rs17850995:rs73013159:rs59716766:rs142158911;rs59716766:rs142158911",48]
["ENSG00000142444","C19orf52",19,11039409,11044211,1,"protein_coding",90580,"C19orf52",0.00198991933916563,-0.096033732,1,0.761,8,{"v":7.92387e-07,"d":"7.92E-07"},0.000675759,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-50,"d":"1.80E-50"},"rs17850995;rs140493437;rs12052200:rs737337:rs56048141:rs56121005:rs17850995:rs73013159:rs59716766:rs142158911;rs59716766:rs142158911",48]
["ENSG00000127616","SMARCA4",19,11071598,11176071,1,"protein_coding",6597,"SMARCA4",0.999999997611829,"NA",20,6.021,21,{"v":1.45947E-7,"d":"1.46E-07"},0.000589482,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","+","Yes","Adult_Cortex",{"v":9.3e-23,"d":"9.30E-23"},"rs73013159;rs12052200;rs59716766;rs140493437;rs12052200:rs737337:rs56048141:rs56121005",48]
["ENSG00000130164","LDLR",19,11200038,11244492,1,"protein_coding",3949,"LDLR",{"v":2.59266073718312e-16,"d":"2.59E-16"},0.415051182,61,13.85,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.8e-50,"d":"1.80E-50"},"rs142158911;rs59716766;rs8102912;rs73015030;rs5742911;rs201091555;rs12052200:rs56121005:rs17850995:rs73013159",48]
["ENSG00000161888","SPC24",19,11242196,11266484,-1,"protein_coding",147841,"SPC24",0.00627554442927794,3.9978869,20,8.935,7,{"v":4.69354e-07,"d":"4.69E-07"},{"v":8.81193e-14,"d":"8.81E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","No","NA",{"v":2.5e-17,"d":"2.50E-17"},"rs5742911;rs201091555;rs79668907;rs746442994",48]
["ENSG00000197256","KANK2",19,11274943,11308467,-1,"protein_coding",25959,"KANK2",0.981511998562845,1.108914572,17,9.828,2,1.1835E-4,{"v":7.22586e-11,"d":"7.23E-11"},"GTEx/v8/Artery_Tibial","-","No","NA",{"v":2e-17,"d":"2.00E-17"},"rs746442994;rs146576912;rs111279811;rs737337;rs56048141",48]
["ENSG00000130158","DOCK6",19,11309971,11373157,-1,"protein_coding",57572,"DOCK6",{"v":2.83089712599404e-19,"d":"2.83E-19"},"NA",57,23.1,40,{"v":1.10227E-6,"d":"1.10E-06"},{"v":2.69192e-05,"d":"2.69E-05"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","No","NA",{"v":5.3e-20,"d":"5.30E-20"},"rs737337;rs56048141;rs56322906;rs201019550;rs72996217",48]
["ENSG00000130173","C19orf80",19,11348178,11352619,1,"protein_coding",55908,"C19orf80",{"v":2.61107498638975e-06,"d":"2.61E-06"},-0.019228124,17,23.1,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.3e-20,"d":"5.30E-20"},"rs737337;rs56322906;rs72996217;rs72996217:rs36022659",48]
["ENSG00000130167","TSPAN16",19,11406824,11437672,1,"protein_coding",26526,"TSPAN16",2.52237775125353E-4,0.747581914,8,10.45,0,"NA","NA","NA","NA","No","NA",{"v":2.3e-11,"d":"2.30E-11"},"rs36022659;rs56121005",48]
["ENSG00000105514","RAB3D",19,11432722,11456946,-1,"protein_coding",9545,"RAB3D",1.42628412727186E-3,1.561182437,1,3.491,0,"NA","NA","NA","NA","No","NA",{"v":4.1e-08,"d":"4.10E-08"},"rs147275653",48]
["ENSG00000105518","TMEM205",19,11453452,11457194,-1,"protein_coding",374882,"TMEM205",0.394574027164483,-0.471673866,1,3.491,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":9.8e-50,"d":"9.80E-50"},"rs147275653;rs142158911:rs8102912",48]
["ENSG00000183401","CCDC159",19,11455360,11465620,1,"protein_coding",126075,"CCDC159",{"v":9.21303782326294e-05,"d":"9.21E-05"},-0.413632241,1,3.491,0,"NA","NA","NA","NA","No","NA",{"v":4.1e-08,"d":"4.10E-08"},"rs147275653",48]
["ENSG00000105520","DKFZP761J1410",19,11466062,11476374,1,"protein_coding",64748,"PLPPR2",0.990015903872762,"NA",1,3.491,0,"NA","NA","NA","NA","No","NA",{"v":4.1e-08,"d":"4.10E-08"},"rs147275653",48]
["ENSG00000173928","SWSAP1",19,11485361,11487627,1,"protein_coding",126074,"SWSAP1",0.000134670403718243,-0.594213988,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8e-50,"d":"1.80E-50"},"rs17850995:rs12052200:rs142158911:rs59716766:rs5742911:rs79668907:rs746442994:rs737337:rs56048141:rs72996217:rs36022659:rs56121005",48]
["ENSG00000187266","EPOR",19,11488236,11495018,-1,"protein_coding",2057,"EPOR",0.058450671852552,-0.617491308,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005:rs36022659",48]
["ENSG00000205517","RGL3",19,11495017,11530018,-1,"protein_coding",57139,"RGL3",{"v":4.36378939273708E-21,"d":"4.36E-21"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.7E-12,"d":"1.70E-12"},"rs737337:rs56048141:rs56121005:rs12052200:rs746442994",48]
["ENSG00000130175","PRKCSH",19,11546109,11561783,1,"protein_coding",5589,"PRKCSH",0.140789247885124,-0.138498039,0,0,1,1.33552E-4,{"v":3.79207e-08,"d":"3.79E-08"},"GTEx/v8/Adipose_Visceral_Omentum","-","No","NA",{"v":3.2e-28,"d":"3.20E-28"},"rs59716766",48]
["ENSG00000196361","ELAVL3",19,11562141,11591861,-1,"protein_coding",1995,"ELAVL3",0.822602583621291,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.5E-10,"d":"1.50E-10"},"rs72996217:rs36022659",48]
["ENSG00000267477","CTC-398G3.6",19,11577055,11616513,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.5e-17,"d":"2.50E-17"},"rs5742911:rs201091555",48]
["ENSG00000161914","ZNF653",19,11594242,11616738,-1,"protein_coding",115950,"ZNF653",0.142112312658903,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.5e-17,"d":"2.50E-17"},"rs5742911:rs201091555",48]
["ENSG00000130159","ECSIT",19,11616731,11639989,-1,"protein_coding",51295,"ECSIT",0.0156465744672347,0.207619557,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000130176","CNN1",19,11649532,11661138,1,"protein_coding",1264,"CNN1",0.861520643189048,0.484495763,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs746442994:rs56121005",48]
["ENSG00000130165","ELOF1",19,11661962,11670051,-1,"protein_coding",84337,"ELOF1",0.403135808004397,0.065704825,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005:rs746442994",48]
["ENSG00000198551","ZNF627",19,11670189,11729950,1,"protein_coding",199692,"ZNF627",0.00564414625423386,0.583732004,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005:rs746442994",48]
["ENSG00000102575","ACP5",19,11685475,11689823,-1,"protein_coding",54,"ACP5",0.123568347500175,-0.16646465,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.8e-50,"d":"1.80E-50"},"rs12052200:rs142158911:rs59716766:rs746442994:rs737337:rs56048141:rs72996217:rs36022659:rs56121005",48]
["ENSG00000197044","ZNF441",19,11877815,11894893,1,"protein_coding",126068,"ZNF441",0.0276670958531812,0.24896725,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.1e-09,"d":"1.10E-09"},"rs746442994",48]
["ENSG00000177599","ZNF491",19,11908482,11920437,1,"protein_coding",126069,"ZNF491",{"v":5.1306652954028E-7,"d":"5.13E-07"},-0.126939715,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000171291","ZNF439",19,11959541,11994565,1,"protein_coding",90594,"ZNF439",{"v":3.21400432787086E-8,"d":"3.21E-08"},0.642917155,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Left_Ventricle",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005:rs73013159:rs12052200",48]
["ENSG00000198429","ZNF69",19,11998599,12025144,1,"protein_coding",7620,"ZNF69",{"v":7.35111939274279e-05,"d":"7.35E-05"},-0.549690848,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle",{"v":1.7E-12,"d":"1.70E-12"},"rs56121005:rs746442994:rs737337:rs56048141:rs73013159:rs12052200",48]
["ENSG00000196757","ZNF700",19,12035883,12061588,1,"protein_coding",90592,"ZNF700",{"v":4.39166088843519E-11,"d":"4.39E-11"},0.364854347,0,0,4,{"v":4.47579e-05,"d":"4.48E-05"},3.03929E-3,"GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56322906;rs737337;rs56121005",48]
["ENSG00000197054","ZNF763",19,12035890,12091196,1,"protein_coding",284390,"ZNF763",0.000236872840014969,2.327700828,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000267179","ZNF763",19,12035890,12090105,1,"protein_coding",284390,"ZNF763","NA",2.327700828,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000132010","ZNF20",19,12203658,12251222,-1,"protein_coding",7568,"ZNF20",0.0235723668010903,-0.869285434,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000213297","ZNF625-ZNF20",19,12242932,12267546,-1,"protein_coding",100529855,"ZNF625-ZNF20","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000257591","ZNF625",19,12251032,12267546,-1,"protein_coding",90589,"ZNF625",0.000825561501317101,-0.035089358,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000197857","ZNF44",19,12335501,12405702,-1,"protein_coding",51710,"ZNF44",{"v":8.93827649124464e-07,"d":"8.94E-07"},-0.200420885,0,0,1,{"v":6.24594e-05,"d":"6.25E-05"},0.0044816,"GTEx/v8/Artery_Tibial","-","No","NA",{"v":4.1e-08,"d":"4.10E-08"},"rs147275653",48]
["ENSG00000132026","RTBDN",19,12936292,12946242,-1,"protein_coding",83546,"RTBDN",{"v":3.27850963623921e-07,"d":"3.28E-07"},0.068260512,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000105613","MAST1",19,12944765,12985765,1,"protein_coding",22983,"MAST1",0.999999024385856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":2.3e-11,"d":"2.30E-11"},"rs56121005",48]
["ENSG00000141979","CTD-3222D19.2",19,16589878,16739015,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.3e-12,"d":"1.30E-12"},"rs116962777:rs143729015",49]
["ENSG00000105085","MED26",19,16685718,16739873,-1,"protein_coding",9441,"MED26",0.948549941884627,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.3e-12,"d":"1.30E-12"},"rs116962777:rs143729015",49]
["ENSG00000105642","KCNN1",19,18062102,18110889,1,"protein_coding",3780,"KCNN1",0.931699633359926,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3.9e-54,"d":"3.90E-54"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626",49]
["ENSG00000254858","MPV17L2",19,18303992,18307758,1,"protein_coding",84769,"MPV17L2",{"v":1.67296107198305e-07,"d":"1.67E-07"},0.464900432,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.9e-12,"d":"4.90E-12"},"rs143729015",49]
["ENSG00000105650","PDE4C",19,18318771,18366229,-1,"protein_coding",5143,"PDE4C",{"v":4.88574724786651e-05,"d":"4.89E-05"},0.288881628,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":2.1e-08,"d":"2.10E-08"},"rs143729015",49]
["ENSG00000130511","SSBP4",19,18529674,18545372,1,"protein_coding",170463,"SSBP4",0.96165888216155,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":9.7e-11,"d":"9.70E-11"},"rs143729015",49]
["ENSG00000105656","ELL",19,18553473,18632937,-1,"protein_coding",8178,"ELL",0.940941238331597,-0.635599911,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.3e-12,"d":"1.30E-12"},"rs143729015:rs116962777",49]
["ENSG00000105701","FKBP8",19,18642561,18654887,-1,"protein_coding",23770,"FKBP8",0.9787380986207,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.9e-12,"d":"4.90E-12"},"rs143729015",49]
["ENSG00000221983","UBA52",19,18682540,18688360,1,"protein_coding",7311,"UBA52",0.4468000697986,1.709183735,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.3e-12,"d":"1.30E-12"},"rs143729015:rs116962777:rs73001020;rs143729015",49]
["ENSG00000006016","CRLF1",19,18683030,18718551,-1,"protein_coding",9244,"CRLF1",0.026855594173361,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.3e-12,"d":"1.30E-12"},"rs116962777:rs143729015:rs73001020;rs143729015",49]
["ENSG00000006015","C19orf60",19,18699495,18703146,1,"protein_coding",55049,"C19orf60",0.249879077699029,0.549025716,0,0,1,{"v":9.44404e-05,"d":"9.44E-05"},{"v":3.85859E-8,"d":"3.86E-08"},"GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Fetal_Cortex:Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.3e-12,"d":"1.30E-12"},"19:19684139_TAC_T;rs143729015:rs116962777:rs73001020;rs143729015",49]
["ENSG00000105696","TMEM59L",19,18718240,18731849,1,"protein_coding",25789,"TMEM59L",0.0151007864967939,"NA",0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.3e-12,"d":"1.30E-12"},"rs116962777:rs143729015:rs73001020;rs143729015",49]
["ENSG00000105662","CRTC1",19,18794487,18893004,1,"protein_coding",23373,"CRTC1",0.980548236291021,-2.587605964,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.9e-12,"d":"4.90E-12"},"rs143729015",49]
["ENSG00000223802","CERS1",19,18979361,19007536,-1,"protein_coding",10715,"CERS1",0.0454570437212016,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.4e-52,"d":"5.40E-52"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs182611493:rs2285626;rs17216693;19:19510831_AT_A",49]
["ENSG00000130283","GDF1",19,18979361,19006905,-1,"protein_coding",2657,"GDF1",0.544923744446604,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.4e-52,"d":"5.40E-52"},"rs11882123:rs2285626:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs182611493:rs2285626;rs17216693;19:19510831_AT_A",49]
["ENSG00000268193","AC002985.3",19,19017822,19045206,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.4e-54,"d":"1.40E-54"},"rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs144787624",49]
["ENSG00000064607","SUGP2",19,19101697,19144832,-1,"protein_coding",10147,"SUGP2",0.999366871236062,0.523631183,6,12.96,20,{"v":6.38872E-7,"d":"6.39E-07"},{"v":4.0018e-05,"d":"4.00E-05"},"GTEx/v8/Adipose_Subcutaneous","-","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.5e-62,"d":"5.50E-62"},"rs143729015;rs73001020;rs116962777;rs113954889;rs143729015:rs113954889:rs8100140:rs11882123:rs58542926:rs2285626:rs144787624:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs113954889;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:19:19269404_GA_G:rs144024112",49]
["ENSG00000105676","ARMC6",19,19144384,19170563,1,"protein_coding",93436,"ARMC6",{"v":7.24407726209859e-07,"d":"7.24E-07"},"NA",1,0.21,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":5.5e-62,"d":"5.50E-62"},"rs143729015;rs143729015:rs113954889:rs8100140:rs11882123:rs58542926:rs2285626:rs144787624:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs2285626;19:19510831_AT_A:19:19510831_AT_A:rs58542926;rs2285626:rs73001020:rs73001020;rs143729015:rs113954889;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:19:19269404_GA_G:rs144024112",49]
["ENSG00000181035","SLC25A42",19,19174808,19223697,1,"protein_coding",284439,"SLC25A42",0.208308450498004,-0.880389707,1,0.194,1,{"v":6.84166e-05,"d":"6.84E-05"},0.0196554,"GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.8e-16,"d":"1.80E-16"},"rs143729015;19:19684139_TAC_T;rs116962777:rs143729015:rs113954889;rs28672836:rs28672836:19:19260892_CAAAAAAAAA_C:rs113954889:19:19269404_GA_G",49]
["ENSG00000064545","TMEM161A",19,19229978,19249322,-1,"protein_coding",54929,"TMEM161A",{"v":2.04658505555468e-06,"d":"2.05E-06"},-0.270254201,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":7e-55,"d":"7.00E-55"},"rs116962777:rs143729015:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs2285626:rs182611493:rs58542926:rs144787624:rs144024112",49]
["ENSG00000064489","MEF2BNB-MEF2B",19,19256376,19302967,-1,"protein_coding",4207,"MEF2BNB-MEF2B",0.247287511423171,-0.149548186,57,12.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4e-54,"d":"1.40E-54"},"rs113954889;rs28672836;19:19260892_CAAAAAAAAA_C;19:19269404_GA_G;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",49]
["ENSG00000213999","MEF2B",19,19256377,19303400,-1,"protein_coding",100271849,"MEF2B",0.590447262915793,"NA",57,12.47,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4e-54,"d":"1.40E-54"},"rs113954889;rs28672836;19:19260892_CAAAAAAAAA_C;19:19269404_GA_G;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",49]
["ENSG00000254901","MEF2BNB",19,19287712,19303400,-1,"protein_coding",729991,"MEF2BNB","NA",0.579437175,21,9.408,12,{"v":1.42511E-7,"d":"1.43E-07"},{"v":3.62201e-19,"d":"3.62E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4e-54,"d":"1.40E-54"},"rs113954889;rs8100140;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",49]
["ENSG00000064490","RFXANK",19,19303008,19312678,1,"protein_coding",8625,"RFXANK",0.000671163624692492,0.789997306,9,9.408,3,0.000100607,0.0177117,"GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.4e-54,"d":"1.40E-54"},"rs113954889;rs8100140;rs182611493;rs73001020;rs73001020:rs2285626;rs17216693;19:19510831_AT_A:rs11882123:rs2285626;19:19510831_AT_A:rs2285626:rs143729015:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs58542926;rs2285626:rs144787624",49]
["ENSG00000184162","NR2C2AP",19,19312225,19314233,-1,"protein_coding",126382,"NR2C2AP",0.527167735331819,-0.417894074,2,6.326,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":3.9e-54,"d":"3.90E-54"},"rs8100140;rs182611493;rs113954889:rs58542926;rs2285626:rs11882123:rs2285626;19:19510831_AT_A:rs73001020:rs58542926:rs2285626",49]
["ENSG00000130287","NCAN",19,19322782,19363042,1,"protein_coding",1463,"NCAN",0.154546738217425,-1.280770396,8,23,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":5.5e-62,"d":"5.50E-62"},"rs8100140;rs182611493;19:19324314_TG_T;rs3761077;rs58542926;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs182611493:19:19510831_AT_A:rs144787624",49]
["ENSG00000187664","HAPLN4",19,19366450,19373605,-1,"protein_coding",404037,"HAPLN4",0.0326847848265823,0.204997517,18,26.2,199,{"v":6.79586E-20,"d":"6.80E-20"},{"v":6.88492e-19,"d":"6.88E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","EP_correlation_cell_type_oneway",{"v":2.7e-62,"d":"2.70E-62"},"rs58542926;rs11882123;rs2285626;19:19510831_AT_A;rs144024112;rs182611493;19:19684139_TAC_T;rs17216693;rs7245672;rs143333049;rs8100204",49]
["ENSG00000213996","TM6SF2",19,19375173,19384200,-1,"protein_coding",53345,"TM6SF2",{"v":1.93541173325793e-05,"d":"1.94E-05"},"NA",36,26.2,267,{"v":1.17275e-20,"d":"1.17E-20"},{"v":8.90299e-16,"d":"8.90E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":2.7e-62,"d":"2.70E-62"},"rs58542926;rs11882123;rs2285626;19:19510831_AT_A;rs144024112;rs182611493;rs35431065;rs8100204;rs17216693;19:19684139_TAC_T;rs7245672;19:19756073_AGCC_A;rs143729015:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs144787624",49]
["ENSG00000105705","SUGP1",19,19386827,19431653,-1,"protein_coding",57794,"SUGP1",0.9996355600486,"NA",86,26.2,13,{"v":4.84498e-06,"d":"4.84E-06"},{"v":5.87709e-05,"d":"5.88E-05"},"GTEx/v8/Heart_Left_Ventricle","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":2.7e-62,"d":"2.70E-62"},"rs11882123;rs144024112;rs58542926;rs182611493;rs2285626;19:19510831_AT_A;rs35431065;rs8100204;rs73001020;rs17216693;rs747862826;19:19438110_GTATT_G;rs7245672;rs11882123:rs2285626:rs2285626",49]
["ENSG00000129933","MAU2",19,19431490,19469563,1,"protein_coding",23383,"MAU2",0.999717755369344,0.014423646,88,15.92,20,{"v":2.45442e-05,"d":"2.45E-05"},0.0377692,"GTEx/v8/Heart_Atrial_Appendage","+","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":7e-55,"d":"7.00E-55"},"rs2285626;19:19510831_AT_A;rs11882123;rs58542926;rs747862826;19:19438110_GTATT_G;rs73001020;rs182611493;rs144787624;rs144024112;rs11882123:rs2285626:rs2285626",49]
["ENSG00000167491","GATAD2A",19,19496635,19619740,1,"protein_coding",54815,"GATAD2A",0.995362828250654,-0.496926306,123,19.09,29,{"v":9.95736e-06,"d":"9.96E-06"},0.0106309,"GTEx/v8/Adipose_Subcutaneous","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":7e-55,"d":"7.00E-55"},"rs11882123;rs2285626;19:19510831_AT_A;rs58542926;19:19756073_AGCC_A;rs17216693;rs73001020;19:19684139_TAC_T;rs77653002;rs144787624;rs144024112;rs143729015:rs11882123:rs58542926:rs2285626;19:19510831_AT_A:rs58542926;rs2285626:rs2285626:rs144787624",49]
["ENSG00000178093","TSSK6",19,19623227,19626838,-1,"protein_coding",83983,"TSSK6",0.587550746537451,-1.568432771,21,19.09,25,{"v":8.90205e-06,"d":"8.90E-06"},{"v":3.58402e-05,"d":"3.58E-05"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex",{"v":2.2e-40,"d":"2.20E-40"},"rs11882123;rs2285626;rs144787624;rs144024112;rs17216693;19:19510831_AT_A;rs7245672;rs11882123:rs2285626",49]
["ENSG00000186010","NDUFA13",19,19626545,19644285,1,"protein_coding",51079,"NDUFA13",1.21026586319051E-4,-0.285091511,24,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":8.6e-40,"d":"8.60E-40"},"rs11882123;rs144787624;rs2285626;rs144024112;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",49]
["ENSG00000250067","YJEFN3",19,19627036,19648390,1,"protein_coding",374887,"YJEFN3",{"v":2.63542608769062e-06,"d":"2.64E-06"},"NA",24,19.09,224,{"v":1.26288E-18,"d":"1.26E-18"},{"v":3.19891e-16,"d":"3.20E-16"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex",{"v":5.5e-62,"d":"5.50E-62"},"rs11882123;rs144787624;rs2285626;rs144024112;rs17216693;19:19510831_AT_A;rs58542926;rs73001020;19:19756073_AGCC_A;rs7245672;rs143729015;19:19684139_TAC_T;rs11882123:rs2285626",49]
["ENSG00000258674","CTC-260F20.3",19,19627036,19646885,1,"protein_coding","NA","NA","NA","NA",22,19.09,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":8.6e-40,"d":"8.60E-40"},"rs11882123;rs144787624;rs2285626;rs144024112;rs17216693;19:19510831_AT_A;rs11882123:rs2285626",49]
["ENSG00000160161","CILP2",19,19649057,19657468,1,"protein_coding",148113,"CILP2",0.000278936233123941,-0.132917182,16,11.63,170,{"v":2.5641e-19,"d":"2.56E-19"},{"v":7.52088e-21,"d":"7.52E-21"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":1.4e-54,"d":"1.40E-54"},"rs11882123;rs2285626;rs17216693;19:19510831_AT_A;rs58542926;19:19684139_TAC_T;rs7245672;rs182611493:19:19324314_TG_T:rs3761077:rs58542926;rs3761077:rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:rs144787624:rs144024112:rs2285626;19:19510831_AT_A:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672",49]
["ENSG00000105717","PBX4",19,19672522,19729725,-1,"protein_coding",80714,"PBX4",0.006772126187306,-0.679896521,74,18.31,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.5e-52,"d":"7.50E-52"},"rs58542926;rs17216693;19:19684139_TAC_T;rs7245672;19:19756073_AGCC_A;19:19684139_TAC_T:rs7245672:rs58542926",49]
["ENSG00000064547","LPAR2",19,19734477,19739739,-1,"protein_coding",9170,"LPAR2",0.337269896843433,-0.426142953,19,18.31,168,{"v":4.1384e-34,"d":"4.14E-34"},{"v":1.22846e-27,"d":"1.23E-27"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":1.7E-51,"d":"1.70E-51"},"rs7245672;19:19684139_TAC_T;rs58542926;19:19756073_AGCC_A;rs11882123",49]
["ENSG00000089639","GMIP",19,19740285,19754476,-1,"protein_coding",51291,"GMIP",{"v":7.29298933296636e-05,"d":"7.29E-05"},-0.277164354,15,18.31,14,{"v":3.96674e-08,"d":"3.97E-08"},1.36079E-4,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta","-","Yes","EP_correlation_cell_type_oneway",{"v":1.3e-48,"d":"1.30E-48"},"19:19684139_TAC_T;rs7245672;rs58542926;19:19756073_AGCC_A;rs11882123",49]
["ENSG00000105726","ATP13A1",19,19756007,19774502,-1,"protein_coding",57130,"ATP13A1",0.994473888962369,"NA",4,8.763,103,{"v":3.16696e-16,"d":"3.17E-16"},{"v":9.80314e-12,"d":"9.80E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":2.7e-62,"d":"2.70E-62"},"rs58542926;19:19756073_AGCC_A;19:19684139_TAC_T;rs143729015;rs113954889;rs3761077;rs35431065;rs8100204;rs73001020;rs17216693;rs2285626;19:19510831_AT_A;rs143333049;rs7245672;19:19684139_TAC_T:rs7245672:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs11882123:rs58542926:rs2285626:rs144787624:rs117414940",49]
["ENSG00000181896","ZNF101",19,19779605,19794318,1,"protein_coding",94039,"ZNF101",{"v":5.76614320550034e-07,"d":"5.77E-07"},-0.001974248,5,11.91,45,{"v":2.56484E-5,"d":"2.56E-05"},{"v":2.22273E-14,"d":"2.22E-14"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":1.4e-54,"d":"1.40E-54"},"19:19756073_AGCC_A;rs143333049;rs113954889;rs58542926;rs3761077;rs7245672;rs11882123:19:19684139_TAC_T:rs7245672:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs58542926:rs2285626:rs144787624:rs117414940",49]
["ENSG00000105708","ZNF14",19,19821280,19843906,-1,"protein_coding",7561,"ZNF14",{"v":5.71582699182454e-16,"d":"5.72E-16"},-0.140934352,1,0.401,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Fetal_Cortex:Mesendoderm",{"v":3.7e-54,"d":"3.70E-54"},"rs117414940;rs58542926:rs2285626;19:19510831_AT_A:rs11882123:rs58542926;rs2285626:rs2285626:19:19756073_AGCC_A:rs143333049",49]
["ENSG00000081665","ZNF506",19,19896648,19932560,-1,"protein_coding",440515,"ZNF506",{"v":1.99612668014446E-8,"d":"2.00E-08"},-0.298399589,0,0,14,{"v":4.66246e-05,"d":"4.66E-05"},{"v":1.69948E-26,"d":"1.70E-26"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Left_Ventricle","-","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":8.7e-55,"d":"8.70E-55"},"rs58542926;rs17216693;19:19756073_AGCC_A;rs73001020;rs2285626;rs117414940:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049:19:19756073_AGCC_A",49]
["ENSG00000256771","ZNF253",19,19976695,20005483,1,"protein_coding",56242,"ZNF253",{"v":1.33295852799606e-06,"d":"1.33E-06"},0.279040894,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.1e-15,"d":"1.10E-15"},"rs117414940:rs143333049",49]
["ENSG00000184635","ZNF93",19,20011722,20046384,1,"protein_coding",81931,"ZNF93",0.00169182185612759,0.174728697,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.3E-51,"d":"1.30E-51"},"rs117414940:rs143333049:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:19:19756073_AGCC_A",49]
["ENSG00000268461","AC007204.1",19,20047769,20048639,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.5e-52,"d":"7.50E-52"},"rs11882123:rs2285626:rs2285626;rs17216693;19:19510831_AT_A:rs58542926;rs17216693:rs17216693:19:19684139_TAC_T:rs7245672:rs58542926;19:19756073_AGCC_A:19:19756073_AGCC_A:rs117414940:rs143333049",49]
["ENSG00000197124","ZNF682",19,20107867,20150315,-1,"protein_coding",91120,"ZNF682",{"v":3.67329437341058e-09,"d":"3.67E-09"},1.212036464,0,0,1,{"v":9.3218e-05,"d":"9.32E-05"},0.00051934,"GTEx/v8/Artery_Tibial","-","No","NA",{"v":5.5e-62,"d":"5.50E-62"},"rs58542926",49]
["ENSG00000213988","ZNF90",19,20188803,20237885,1,"protein_coding",7643,"ZNF90",{"v":1.22410273221888e-07,"d":"1.22E-07"},1.219480619,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.3E-51,"d":"1.30E-51"},"rs117414940:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049",49]
["ENSG00000256229","ZNF486",19,20278037,20311299,1,"protein_coding",90649,"ZNF486",{"v":1.88053183954875e-08,"d":"1.88E-08"},1.705728223,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.3E-51,"d":"1.30E-51"},"19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs117414940",49]
["ENSG00000237440","ZNF737",19,20718631,20748615,-1,"protein_coding",100129842,"ZNF737",{"v":1.10579189398794E-7,"d":"1.11E-07"},1.355633218,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":1.1e-15,"d":"1.10E-15"},"rs117414940:rs143333049",49]
["ENSG00000188171","ZNF626",19,20802867,20844402,-1,"protein_coding",199777,"ZNF626",{"v":2.3449662444854E-7,"d":"2.34E-07"},10.77102824,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.3E-51,"d":"1.30E-51"},"rs117414940:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672",49]
["ENSG00000160229","ZNF66",19,20959110,20991922,1,"protein_coding",7617,"ZNF66",{"v":5.45295491875167e-17,"d":"5.45E-17"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2e-08,"d":"3.20E-08"},"rs117414940",49]
["ENSG00000118620","ZNF430",19,21203426,21242856,1,"protein_coding",80264,"ZNF430",0.000180790697407956,0.502386975,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049:rs117414940",49]
["ENSG00000160352","ZNF714",19,21264965,21308073,1,"protein_coding",148206,"ZNF714",{"v":7.33708061274363e-06,"d":"7.34E-06"},0.728801136,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs117414940",49]
["ENSG00000182141","ZNF708",19,21473962,21512227,-1,"protein_coding",7562,"ZNF708",{"v":4.17756094613551e-09,"d":"4.18E-09"},1.095220078,0,0,0,"NA","NA","NA","NA","Yes","GM12878:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049:19:19756073_AGCC_A",49]
["ENSG00000172687","ZNF738",19,21541732,21562104,1,"protein_coding",148203,"ZNF738",0.106373218916856,"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:rs143333049:rs117414940",49]
["ENSG00000196268","ZNF493",19,21579921,21610375,1,"protein_coding",284443,"ZNF493",{"v":3.18649368326509e-08,"d":"3.19E-08"},2.729194243,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"rs117414940:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:19:19756073_AGCC_A:rs143333049",49]
["ENSG00000269237","CTD-2561J22.3",19,21587961,21674068,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"rs117414940:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672:19:19756073_AGCC_A:rs143333049",49]
["ENSG00000197013","ZNF429",19,21679484,21739072,1,"protein_coding",353088,"ZNF429",{"v":9.7121420957407e-14,"d":"9.71E-14"},-0.124310103,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.3E-51,"d":"1.30E-51"},"rs117414940:19:19684139_TAC_T:rs58542926;19:19756073_AGCC_A:rs7245672",49]
["ENSG00000197020","ZNF100",19,21905568,21950430,-1,"protein_coding",163227,"ZNF100",{"v":7.10189425692909e-13,"d":"7.10E-13"},1.454526972,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":1.1e-15,"d":"1.10E-15"},"rs117414940:rs143333049",49]
["ENSG00000160321","ZNF208",19,22115760,22193751,-1,"protein_coding",7757,"ZNF208",{"v":5.00161251193924e-20,"d":"5.00E-20"},-0.087489856,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs117414940",49]
["ENSG00000196109","ZNF676",19,22361893,22379753,-1,"protein_coding",163223,"ZNF676",{"v":1.6869849435551e-06,"d":"1.69E-06"},0.244027382,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.2e-08,"d":"3.20E-08"},"rs117414940",49]
["ENSG00000197360","ZNF98",19,22573821,22715287,-1,"protein_coding",148198,"ZNF98",{"v":1.80227058167028E-6,"d":"1.80E-06"},0.029177521,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":1.1e-15,"d":"1.10E-15"},"rs143333049",49]
["ENSG00000007129","CEACAM21",19,42055886,42093197,1,"protein_coding",90273,"CEACAM21",{"v":2.37927718675089e-10,"d":"2.38E-10"},0.224041523,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000105352","CEACAM4",19,42125344,42133442,-1,"protein_coding",1089,"CEACAM4",{"v":1.67959503585306e-06,"d":"1.68E-06"},0.380841519,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.4e-06,"d":"1.40E-06"},"rs62116778",50]
["ENSG00000007306","CEACAM7",19,42177235,42210895,-1,"protein_coding",1087,"CEACAM7",{"v":9.14464756921175e-07,"d":"9.14E-07"},-0.513121247,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000105388","CEACAM5",19,42212504,42233718,1,"protein_coding",1048,"CEACAM5",{"v":3.66899588817934e-05,"d":"3.67E-05"},-0.198121862,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000267881","CEA",19,42212531,42265190,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000183103","LYPD4",19,42341148,42348760,-1,"protein_coding",147719,"LYPD4",{"v":3.41494476753975E-5,"d":"3.41E-05"},-0.551774341,0,0,0,"NA","NA","NA","NA","Yes","hESC",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000142025","DMRTC2",19,42348806,42356401,1,"protein_coding",63946,"DMRTC2",0.726527694192844,-0.470761653,0,0,0,"NA","NA","NA","NA","Yes","hESC",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000079435","LIPE",19,42905659,42931578,-1,"protein_coding",3991,"LIPE",{"v":5.7325054658036e-09,"d":"5.73E-09"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-9,"d":"1.50E-09"},"rs62116778:rs151330717",50]
["ENSG00000189377","CXCL17",19,42932440,42947200,-1,"protein_coding",284340,"CXCL17",0.0285883727188355,0.421463847,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.5E-9,"d":"1.50E-09"},"rs62116778:rs151330717",50]
["ENSG00000124469","CEACAM8",19,43084393,43099207,-1,"protein_coding",1088,"CEACAM8",{"v":1.24548133374918E-7,"d":"1.25E-07"},-0.378062842,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000124467","PSG8",19,43256838,43359843,-1,"protein_coding",440533,"PSG8",{"v":1.92926054362959E-10,"d":"1.93E-10"},-0.013341309,0,0,0,"NA","NA","NA","NA","Yes","Trophoblast-like_Cell",{"v":8e-09,"d":"8.00E-09"},"rs62116778",50]
["ENSG00000183668","PSG9",19,43715943,43773682,-1,"protein_coding",5678,"PSG9",{"v":2.7470177840116e-14,"d":"2.75E-14"},0.713823935,0,0,0,"NA","NA","NA","NA","Yes","Mesendoderm",{"v":1.8e-06,"d":"1.80E-06"},"rs62116778",50]
["ENSG00000167378","IRGQ",19,44088521,44100287,-1,"protein_coding",126298,"IRGQ",1.19722791198288E-3,-1.836457701,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:19:45474599_AT_A",50]
["ENSG00000124444","ZNF576",19,44100544,44105309,1,"protein_coding",79177,"ZNF576",0.007545747912442,-1.085568404,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:19:45474599_AT_A",50]
["ENSG00000226763","SRRM5",19,44100769,44118649,1,"protein_coding",100170229,"SRRM5",{"v":7.19141934794887e-06,"d":"7.19E-06"},-0.661940966,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:19:45474599_AT_A",50]
["ENSG00000131116","ZNF428",19,44111371,44124026,-1,"protein_coding",126299,"ZNF428",0.720275479182866,-0.650154352,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":7.6e-54,"d":"7.60E-54"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754",50]
["ENSG00000105767","CADM4",19,44126520,44143991,-1,"protein_coding",199731,"CADM4",0.979491544538579,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":7.6e-54,"d":"7.60E-54"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754",50]
["ENSG00000124449","IRGC",19,44220162,44224173,1,"protein_coding",56269,"IRGC",0.0437355066124445,0.538293874,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90",{"v":1.5E-9,"d":"1.50E-09"},"rs151330717:rs62116778",50]
["ENSG00000105771","SMG9",19,44235301,44259142,-1,"protein_coding",56006,"SMG9",{"v":4.84811349964517e-11,"d":"4.85E-11"},0.280820638,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs62120566;rs2965157",50]
["ENSG00000104783","KCNN4",19,44270685,44285409,-1,"protein_coding",3783,"KCNN4",{"v":8.36465970463448e-06,"d":"8.36E-06"},-0.056751192,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":1.4e-06,"d":"1.40E-06"},"rs62116778",50]
["ENSG00000159871","LYPD5",19,44300081,44331358,-1,"protein_coding",284348,"LYPD5",{"v":9.4450522196327e-05,"d":"9.45E-05"},1.755971449,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7e-51,"d":"3.70E-51"},"rs62116778:rs74747585:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs151330717",50]
["ENSG00000167637","ZNF283",19,44331444,44353307,1,"protein_coding",284349,"ZNF283",{"v":4.46246793803596E-8,"d":"4.46E-08"},1.259853166,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7e-51,"d":"3.70E-51"},"rs62116778:rs74747585:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs151330717",50]
["ENSG00000176222","ZNF404",19,44376515,44405537,-1,"protein_coding",342908,"ZNF404",{"v":1.48958552341176E-5,"d":"1.49E-05"},0.204290579,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs62120566;rs2965157",50]
["ENSG00000124459","ZNF45",19,44416781,44439430,-1,"protein_coding",7596,"ZNF45",1.0251198832844E-4,0.299070466,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs62120566;rs2965157",50]
["ENSG00000159905","ZNF221",19,44455375,44471861,1,"protein_coding",7638,"ZNF221",{"v":2.58051484113414e-09,"d":"2.58E-09"},-0.128373786,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Bladder:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.7e-51,"d":"3.70E-51"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",50]
["ENSG00000204920","ZNF155",19,44472014,44502477,1,"protein_coding",7711,"ZNF155",{"v":1.33952561088838e-09,"d":"1.34E-09"},0.435175767,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Bladder:Dorsolateral_Prefrontal_Cortex:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.7e-51,"d":"3.70E-51"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",50]
["ENSG00000159882","ZNF230",19,44507100,44518078,1,"protein_coding",7773,"ZNF230",0.00834108463646319,1.880496895,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138:rs62116778:rs74747585:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs151330717:rs62120566;rs2965157",50]
["ENSG00000159885","ZNF222",19,44529494,44537265,1,"protein_coding",7673,"ZNF222",{"v":9.20501288480146e-11,"d":"9.21E-11"},0.148041701,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157",50]
["ENSG00000267022","ZNF223",19,44529506,44591471,1,"protein_coding",7766,"ZNF223","NA",0.204654881,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157",50]
["ENSG00000178386","ZNF223",19,44555520,44572144,1,"protein_coding",7766,"ZNF223",{"v":5.14224553323192e-09,"d":"5.14E-09"},0.204654881,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157",50]
["ENSG00000186026","ZNF284",19,44576297,44593766,1,"protein_coding",342909,"ZNF284",{"v":7.90018316515337e-09,"d":"7.90E-09"},0.721071866,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs62120566;rs2965157",50]
["ENSG00000267680","ZNF224",19,44598492,44612479,1,"protein_coding",7767,"ZNF224",{"v":2.0744645910844e-09,"d":"2.07E-09"},-0.281087996,1,1.447,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778;rs62116778:rs74747585:rs62120566;rs2965157",50]
["ENSG00000256294","ZNF225",19,44616334,44637027,1,"protein_coding",7768,"ZNF225",{"v":3.36669333303033e-08,"d":"3.37E-08"},0.547354183,1,1.447,1,1.18239E-4,0.00794975,"GTEx/v8/Adipose_Subcutaneous","-","Yes","Left_Ventricle:Liver:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs62116778;rs145887105;rs62116778:rs74747585:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs111784051:rs558516697:rs60389450:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs117310449:rs2238681:rs142042446:rs1081105:rs184017:rs429358;rs142042446;rs184017:rs157580:rs429358;rs184017:rs11668327:19:45402389_CA_C:rs449647:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:rs151330717",50]
["ENSG00000263002","ZNF234",19,44645710,44663156,1,"protein_coding",10780,"ZNF234",{"v":1.07736675935267E-13,"d":"1.08E-13"},-0.020937289,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs62120566;rs2965157",50]
["ENSG00000167380","ZNF226",19,44669226,44682534,1,"protein_coding",7769,"ZNF226",{"v":5.26919185197287e-15,"d":"5.27E-15"},-0.050655376,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs62120566;rs2965157",50]
["ENSG00000131115","ZNF227",19,44711700,44741421,1,"protein_coding",7770,"ZNF227",{"v":1.69159989152872e-05,"d":"1.69E-05"},0.350230355,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157",50]
["ENSG00000159917","ZNF235",19,44732882,44809199,-1,"protein_coding",9310,"ZNF235",{"v":1.85820362433789E-10,"d":"1.86E-10"},-0.818454032,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:Right_Ventricle:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":3.7e-51,"d":"3.70E-51"},"rs62116778:rs74747585:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",50]
["ENSG00000159915","ZNF233",19,44754318,44779470,1,"protein_coding",353355,"ZNF233",{"v":3.27015906549736e-17,"d":"3.27E-17"},-0.066961399,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":6.2e-27,"d":"6.20E-27"},"rs62116778:rs74747585:rs151330717:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918",50]
["ENSG00000062370","ZNF112",19,44830708,44871377,-1,"protein_coding",7771,"ZNF112",0.154211257518811,0.038237323,1,3.21,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":3.7e-51,"d":"3.70E-51"},"rs62116778;rs62116778:rs74747585:rs151330717:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918",50]
["ENSG00000267173","CTC-512J12.6",19,44833848,44905774,-1,"protein_coding","NA","NA","NA","NA",2,3.21,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778;rs62116778:rs62120566;rs2965157",50]
["ENSG00000267508","ZNF285",19,44886459,44905774,-1,"protein_coding",26974,"ZNF285",0.00240305532090865,0.299255157,1,2.232,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778;rs62116778:rs62120566;rs2965157",50]
["ENSG00000167383","ZNF229",19,44921685,44952766,-1,"protein_coding",7772,"ZNF229",{"v":6.30663414582273e-09,"d":"6.31E-09"},2.836421684,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs62120566;rs2965157",50]
["ENSG00000167384","ZNF180",19,44979854,45004576,-1,"protein_coding",7733,"ZNF180",{"v":7.35726181171227e-06,"d":"7.36E-06"},0.745753328,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:hESC",{"v":4.6e-12,"d":"4.60E-12"},"rs62116778:rs62120566;rs2965157",50]
["ENSG00000216588","IGSF23",19,45116940,45140081,1,"protein_coding",147710,"IGSF23","NA",0.573724812,2,3.57,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.6e-54,"d":"7.60E-54"},"rs151330717;rs62120566;rs2965157;rs62117206:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs151330717:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs62116778:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918",50]
["ENSG00000073008","PVR",19,45147098,45166850,1,"protein_coding",5817,"PVR",{"v":5.51101308161619e-07,"d":"5.51E-07"},-0.732916848,6,11.21,7,{"v":2.88042e-08,"d":"2.88E-08"},{"v":1.93464E-13,"d":"1.93E-13"},"GTEx/v8/Artery_Tibial","+","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs62120566;rs2965157;rs76670936;rs151330717:rs62116778:rs74747585:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133",50]
["ENSG00000186567","CEACAM19",19,45165545,45187631,1,"protein_coding",56971,"CEACAM19",{"v":5.7765093789489e-07,"d":"5.78E-07"},0.414157593,15,12.01,19,{"v":8.1714e-11,"d":"8.17E-11"},{"v":5.12446e-17,"d":"5.12E-17"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver","+","Yes","Liver:IMR90:Mesenchymal_Stem_Cell",{"v":7.6e-54,"d":"7.60E-54"},"rs62120566;rs2965157;rs76670936;rs151330717;rs11878852;rs151330717:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754",50]
["ENSG00000213892","CEACAM16",19,45202421,45213986,1,"protein_coding",388551,"CEACAM16",0.0295802581415047,-0.586640098,24,12.82,4,{"v":3.19459E-6,"d":"3.19E-06"},0.00772948,"GTEx/v8/Pancreas","+","Yes","Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":3e-82,"d":"3.00E-82"},"rs76670936;rs151330717;rs62120566;rs111278137;rs11881756;rs11878852;rs112450640;19:45311297_AGCTTG_A;19:45303122_AAAAG_A:rs112450640:rs113914212:rs148933445:19:45311297_AGCTTG_A:19:45303122_AAAAG_A:rs140824606:rs28399607:rs41290120;rs62117160:rs62116778:rs151330717:rs62120566;rs2965157:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs2965157:rs62120566:rs76670936",50]
["ENSG00000069399","BCL3",19,45250962,45263301,1,"protein_coding",602,"BCL3",0.86217268510329,"NA",18,16.89,0,"NA","NA","NA","NA","No","NA",{"v":7.2e-41,"d":"7.20E-41"},"rs200046586;rs62117206;rs4803748;rs148933445;rs762016934;rs140824606",50]
["ENSG00000142273","CBLC",19,45281126,45303891,1,"protein_coding",23624,"CBLC",1.82989540193376E-4,-0.348046092,26,15.89,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:Left_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":1.9e-55,"d":"1.90E-55"},"19:45276590_GTTA_G;rs112450640;19:45311297_AGCTTG_A;19:45303122_AAAAG_A;rs113914212;rs148933445;rs140824606;19:45531618_GT_G;rs149553138:rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs149214960;rs112588918:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",50]
["ENSG00000187244","BCAM",19,45312328,45324673,1,"protein_coding",4059,"BCAM",0.0368511835228543,"NA",42,15.96,2,{"v":3.9611e-08,"d":"3.96E-08"},0.000117881,"GTEx/v8/Artery_Tibial","+","Yes","Left_Ventricle:Spleen:IMR90:Mesenchymal_Stem_Cell",{"v":3e-82,"d":"3.00E-82"},"rs148933445;rs113914212;19:45311297_AGCTTG_A;19:45303122_AAAAG_A;rs140824606;rs28399607;rs41290120;rs62117160;rs766396778;rs28399637;rs2927482;rs149214960;rs752060506;19:45328407_GAC_G;rs6509173;rs7343130;rs2927472;rs766396778:rs28399637:rs2927482:rs149214960:rs752060506:19:45328407_GAC_G:rs6509173:rs7343130:rs2927472;rs6509173:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143:rs71338733;rs112588918:rs71338733:rs2972558:rs71338733;rs112588918:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",50]
["ENSG00000130202","PVRL2",19,45349432,45392485,1,"protein_coding",5819,"PVRL2",0.531937435077773,-0.314456223,123,21.1,41,{"v":1.60823E-20,"d":"1.61E-20"},{"v":1.20145E-26,"d":"1.20E-26"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Fetal_Cortex:Left_Ventricle:IMR90:Mesenchymal_Stem_Cell",{"v":4E-95,"d":"4.00E-95"},"rs2927482;rs149214960;rs112588918;rs61642202;rs2927472;rs111371860;rs566486324;rs3810143;rs71338733;rs2972558;rs375972689;rs12463239;rs3729640;rs768441224;rs33951304;rs395908;rs111784051;rs558516697;rs60389450;rs548051568;rs393584;rs6859;rs41290120;rs1985129;rs117310449;rs2238681;rs142042446;rs1081105;rs184017;rs429358;rs157580;rs11668327;19:45402389_CA_C;19:45311297_AGCTTG_A;rs7343130;rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs111784051:rs112450640;19:45303122_AAAAG_A:rs112450640:rs113914212:rs148933445:19:45311297_AGCTTG_A:19:45303122_AAAAG_A:rs140824606:rs28399607:rs41290120;rs62117160:rs62116778:rs62120566;rs2965157:rs2965157:rs62120566:rs76670936:rs151330717:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748",50]
["ENSG00000130204","TOMM40",19,45393826,45406946,1,"protein_coding",10452,"TOMM40",0.963682323765023,"NA",82,25.1,2,{"v":4.48241e-05,"d":"4.48E-05"},4.8747E-3,"GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.1e-157,"d":"4.10E-157"},"rs1985129;rs117310449;rs2238681;rs142042446;rs1081105;rs111784051;rs184017;rs429358;rs157580;rs11668327;19:45402389_CA_C;rs449647;rs75627662;rs59325138;rs1065853;rs157595;rs3925681:rs1081105:rs374095935:rs157592:rs71352239;rs3925681:rs157595:rs429358;rs157592:rs144311893:rs1065853:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:19:45531618_GT_G;rs149553138:rs62116778:rs79429216:rs12721109",50]
["ENSG00000130203","APOE",19,45409011,45412650,1,"protein_coding",348,"APOE",0.0345335830833016,-0.237445173,54,25.1,9,{"v":1.25337E-5,"d":"1.25E-05"},0.0289608,"GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","-","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs1081105;rs111784051;rs2238681;19:45402389_CA_C;rs449647;rs157580;rs429358;rs75627662;rs59325138;rs1065853;rs157595;rs3925681;rs374095935;rs157592;rs71352239;rs111606839;rs62117206:19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs62116778:rs62120566;rs2965157",50]
["ENSG00000130208","APOC1",19,45417504,45422606,1,"protein_coding",341,"APOC1",0.0507382728810443,-0.105569458,52,25.1,7,{"v":3.55555e-06,"d":"3.56E-06"},0.00882724,"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Heart_Atrial_Appendage","-","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs2238681;rs449647;rs157580;rs429358;rs75627662;rs59325138;rs1065853;rs1081105;rs157595;rs3925681;rs374095935;rs157592;rs71352239;rs144311893;rs60049679;rs5112;rs7246100;rs62117206:rs5112:rs5112;rs7246100:rs7246100:rs7254133:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:19:45531618_GT_G;rs149553138:rs79429216:rs12721109:rs57465754:rs62116778:rs62120566;rs2965157",50]
["ENSG00000224916","APOC4-APOC2",19,45445495,45452822,1,"protein_coding",100533990,"APOC4-APOC2","NA","NA",40,17.4,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs7246100;rs7254133;19:45440145_CTG_C;rs111606839;rs79429216;rs12721109;19:45474599_AT_A;rs62117206:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs151330717:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs558516697:rs60389450:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs117310449:rs142042446:rs184017:rs429358;rs142042446;rs184017:rs429358;rs184017:rs11668327:rs79890446:rs2965157:rs62120566:rs76670936",50]
["ENSG00000267467","APOC4",19,45445495,45452820,1,"protein_coding",346,"APOC4",0.000150692347626422,0.337274035,40,17.4,60,{"v":4.4607e-14,"d":"4.46E-14"},{"v":3.56734e-09,"d":"3.57E-09"},"GTEx/v8/Liver","+","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs7246100;rs7254133;19:45440145_CTG_C;rs111606839;rs79429216;rs12721109;19:45474599_AT_A;rs57465754;rs7245887;rs62117206:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs151330717:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs558516697:rs60389450:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs117310449:rs142042446:rs184017:rs429358;rs142042446;rs184017:rs429358;rs184017:rs11668327:rs79890446:rs2965157:rs62120566:rs76670936",50]
["ENSG00000234906","APOC2",19,45449243,45452822,1,"protein_coding",344,"APOC2",0.0227961322934307,0.388732718,36,17.4,59,{"v":5.34361e-12,"d":"5.34E-12"},{"v":1.21381e-15,"d":"1.21E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","EP_correlation_cell_type_oneway:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"19:45440145_CTG_C;rs111606839;rs79429216;rs12721109;19:45474599_AT_A;rs5112;rs62117206:rs1081105:rs111784051:rs2238681:19:45402389_CA_C:rs449647:rs157580:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs151330717:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs558516697:rs60389450:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs117310449:rs142042446:rs184017:rs429358;rs142042446;rs184017:rs429358;rs184017:rs11668327:rs79890446:rs2965157:rs62120566:rs76670936",50]
["ENSG00000267114","CTB-129P6.11",19,45453301,45457264,-1,"protein_coding","NA","NA","NA","NA",31,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs111606839;rs79429216;19:45440145_CTG_C;rs12721109;19:45474599_AT_A;rs57465754;rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs111784051:rs184017:rs429358;rs142042446;rs184017:rs117310449:rs142042446:rs157580:rs2238681:rs429358;rs184017:rs1081105:rs11668327:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:19:45402389_CA_C:rs449647:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:rs151330717:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs558516697:rs60389450:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs79890446:rs2965157:rs62120566:rs76670936",50]
["ENSG00000104853","CLPTM1",19,45457842,45496599,1,"protein_coding",1209,"CLPTM1",0.98048307691788,"NA",95,17.4,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"rs111606839;19:45440145_CTG_C;19:45474599_AT_A;rs57465754;rs117261169;19:45500884_CT_C;rs79429216;rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs111784051:rs184017:rs429358;rs142042446;rs184017:rs117310449:rs142042446:rs157580:rs2238681:rs429358;rs184017:rs1081105:rs11668327:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:19:45531618_GT_G;rs149553138:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:19:45402389_CA_C:rs449647:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:rs151330717:rs62120566;rs2965157:rs111278137:rs11881756:rs11878852:19:45224670_GA_G:rs587766117:rs10522867:rs62117206:rs62117160:rs10522867;19:45233631_CA_C:19:45233631_CA_C:rs4803748:rs558516697:rs60389450:rs548051568:rs393584:rs6859:rs41290120:rs1985129:rs79890446:rs2965157:rs62120566:rs76670936",50]
["ENSG00000104856","RELB",19,45504688,45541452,1,"protein_coding",5971,"RELB",0.973562746007932,"NA",44,17.21,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":2e-36,"d":"2.00E-36"},"rs111606839;19:45440145_CTG_C;19:45474599_AT_A;rs57465754;19:45500884_CT_C;rs79429216;19:45506732_CAAAA_C;rs140912273;rs7245887;rs145887105;rs200756447;19:45531618_GT_G;rs149553138;rs62117206",50]
["ENSG00000104859","CLASRP",19,45542298,45574214,1,"protein_coding",11129,"CLASRP",0.964966482147783,-0.085202503,1,1.868,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":4.1e-157,"d":"4.10E-157"},"19:45531618_GT_G;rs149553138;rs181765708:rs375972689:rs12463239:rs3729640:rs768441224:rs33951304:rs395908:rs111784051:rs184017:rs429358;rs142042446;rs184017:rs117310449:rs142042446:rs157580:rs2238681:rs429358;rs184017:rs1081105:rs11668327:rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:rs5112:rs5112;rs7246100:rs7246100:rs7254133:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:rs7245887:rs145887105:rs200756447:rs79429216:rs12721109:rs79890446",50]
["ENSG00000170684","ZNF296",19,45574758,45579846,-1,"protein_coding",162979,"ZNF296",0.97328866403764,"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"rs181765708:19:45531618_GT_G;rs149553138",50]
["ENSG00000142252","GEMIN7",19,45582453,45594782,1,"protein_coding",79760,"GEMIN7",0.347103990823881,-0.101681128,0,0,16,{"v":1.16893E-5,"d":"1.17E-05"},{"v":4.76054E-23,"d":"4.76E-23"},"GTEx/v8/Artery_Tibial","+","No","NA",{"v":4.2e-09,"d":"4.20E-09"},"19:45440145_CTG_C",50]
["ENSG00000007047","MARK4",19,45582546,45808541,1,"protein_coding",57787,"MARK4",0.999932135718548,"NA",3,7.261,16,{"v":2.43126e-09,"d":"2.43E-09"},{"v":1.70606e-05,"d":"1.71E-05"},"GTEx/v8/Artery_Aorta","-","No","NA",{"v":1.2e-28,"d":"1.20E-28"},"rs12721109;rs149553138;rs79890446;19:45440145_CTG_C",50]
["ENSG00000104866","PPP1R37",19,45594654,45651335,1,"protein_coding",284352,"PPP1R37","NA",0.143949947,1,7.261,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"rs12721109;19:45531618_GT_G;rs149553138",50]
["ENSG00000179846","NKPD1",19,45653008,45663408,-1,"protein_coding",284353,"NKPD1",{"v":1.88741865526868e-09,"d":"1.89E-09"},"NA",2,7.261,0,"NA","NA","NA","NA","No","NA",{"v":1.2e-28,"d":"1.20E-28"},"rs12721109;rs149553138",50]
["ENSG00000007255","TRAPPC6A",19,45666186,45681495,-1,"protein_coding",79090,"TRAPPC6A",0.000705277787371492,-0.133842318,1,0.065,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.1e-157,"d":"4.10E-157"},"rs149553138;rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs1081105:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:19:45531618_GT_G;rs149553138:rs181765708:rs2927482:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143",50]
["ENSG00000189114","BLOC1S3",19,45682003,45685059,1,"protein_coding",388552,"BLOC1S3",0.0184297702580611,-0.115773028,1,0.065,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.1e-157,"d":"4.10E-157"},"rs149553138;rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs1081105:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:19:45531618_GT_G;rs149553138:rs181765708:rs2927482:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143",50]
["ENSG00000267545","AC005779.2",19,45683080,45705702,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.1e-157,"d":"4.10E-157"},"rs429358;rs75627662:rs59325138;rs2238681:rs429358:rs1065853:rs1081105:rs75627662:rs157595:rs59325138:rs3925681:rs374095935:rs157592:rs71352239;rs59325138;rs3925681:rs429358;rs157592:rs144311893:rs71352239:rs60049679:19:45440145_CTG_C:rs111606839:19:45474599_AT_A:rs57465754:19:45531618_GT_G;rs149553138:rs181765708:rs2927482:rs149214960;rs112588918:rs112588918:rs61642202:rs2927472:rs111371860:rs566486324:rs3810143",50]
["ENSG00000266958","AC006126.3",19,45690646,45720191,1,"protein_coding","NA","NA","NA","NA",1,0.062,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.9e-55,"d":"1.90E-55"},"rs79890446;rs113914212:rs148933445:19:45311297_AGCTTG_A:19:45303122_AAAAG_A:19:45440145_CTG_C:rs111606839:19:45474599_AT_A",50]
["ENSG00000130201","EXOC3L2",19,45715879,45737469,-1,"protein_coding",90332,"EXOC3L2",0.925564031557031,"NA",1,0.062,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":7.6e-54,"d":"7.60E-54"},"rs79890446;19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:19:45531618_GT_G;rs149553138:rs181765708",50]
["ENSG00000104879","CKM",19,45809672,45826235,-1,"protein_coding",1158,"CKM",0.00505058616928749,0.03849229,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":7.6e-54,"d":"7.60E-54"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs79890446:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:19:45531618_GT_G;rs149553138",50]
["ENSG00000104892","KLC3",19,45836692,45854778,1,"protein_coding",147700,"KLC3",{"v":3.15849310261577e-06,"d":"3.16E-06"},"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":7.6e-54,"d":"7.60E-54"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs79890446:rs7245887:rs145887105:rs200756447:19:45531618_GT_G:19:45531618_GT_G;rs149553138",50]
["ENSG00000268341","L47234.1",19,45842445,45842639,1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.6e-54,"d":"7.60E-54"},"19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs79890446",50]
["ENSG00000104884","ERCC2",19,45853095,45874176,-1,"protein_coding",2068,"ERCC2",{"v":3.14163491830693e-13,"d":"3.14E-13"},-0.123245341,1,0.743,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.6e-54,"d":"7.60E-54"},"rs181765708;19:45440145_CTG_C:rs111606839:rs79429216:rs12721109:19:45474599_AT_A:rs57465754:rs79890446",50]
["ENSG00000104881","PPP1R13L",19,45882892,45909607,-1,"protein_coding",10848,"PPP1R13L",0.00265401837731973,-0.293274669,2,0.743,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":7.7e-13,"d":"7.70E-13"},"rs181765708;rs79890446",50]
["ENSG00000117877","CD3EAP",19,45909467,45914024,1,"protein_coding",10849,"CD3EAP",{"v":5.68877488151799e-05,"d":"5.69E-05"},1.568549218,1,0.241,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3e-12,"d":"3.00E-12"},"rs181765708;rs79890446",50]
["ENSG00000012061","ERCC1",19,45910591,45982086,-1,"protein_coding",2067,"ERCC1",0.000286883321902936,-0.011078743,1,0.241,6,{"v":2.72709E-5,"d":"2.73E-05"},{"v":8.93421e-09,"d":"8.93E-09"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","GM12878:IMR90",{"v":6.3e-15,"d":"6.30E-15"},"rs181765708;rs2927482",50]
["ENSG00000125740","FOSB",19,45971253,45978437,1,"protein_coding",2354,"FOSB",0.852916176747718,-1.205388313,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway:Adult_Cortex:Fetal_Cortex:GM12878:IMR90",{"v":1.2e-35,"d":"1.20E-35"},"rs181765708:19:45531618_GT_G;rs149553138",50]
["ENSG00000125744","RTN2",19,45988547,46000319,-1,"protein_coding",6253,"RTN2",0.636179982447555,"NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":7.7e-13,"d":"7.70E-13"},"rs181765708",50]
["ENSG00000213889","PPM1N",19,45992035,46005768,1,"protein_coding",147699,"PPM1N",1.04897385207125E-4,-0.142647997,0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90",{"v":7.7e-13,"d":"7.70E-13"},"rs181765708",50]
["ENSG00000125753","VASP",19,46009837,46030241,1,"protein_coding",7408,"VASP",0.583670616080661,-0.335330773,1,0.158,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":4.9E-9,"d":"4.90E-09"},"rs181765708",50]
["ENSG00000125746","EML2",19,46110252,46148887,-1,"protein_coding",24139,"EML2",{"v":7.57699496433696e-10,"d":"7.58E-10"},0.190257397,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"rs111606839:19:45474599_AT_A:rs117261169:19:45440145_CTG_C:rs57465754:19:45500884_CT_C:rs79429216:19:45506732_CAAAA_C:rs140912273:19:45531618_GT_G;rs149553138",50]
["ENSG00000267757","C19orf83",19,46144752,46146098,1,"protein_coding",100287177,"C19orf83","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"rs111606839:19:45474599_AT_A:rs117261169:19:45440145_CTG_C:rs57465754:19:45500884_CT_C:rs79429216:19:45506732_CAAAA_C:rs140912273:19:45531618_GT_G;rs149553138",50]
["ENSG00000125743","SNRPD2",19,46190712,46195827,-1,"protein_coding",6633,"SNRPD2",0.747515256284436,-0.475801412,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000011478","QPCTL",19,46195741,46207247,1,"protein_coding",54814,"QPCTL",0.000261539862441849,-0.638078993,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000177051","FBXO46",19,46213887,46234162,-1,"protein_coding",23403,"FBXO46",0.876437042044124,0.090543664,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138:rs181765708",50]
["ENSG00000237452","AC074212.3",19,46236509,46267792,1,"protein_coding",388553,"BHMG1",0.376320934323438,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138:rs181765708",50]
["ENSG00000104941","RSPH6A",19,46298968,46318577,-1,"protein_coding",81492,"RSPH6A",{"v":2.54884442731765e-08,"d":"2.55E-08"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1.8E-51,"d":"1.80E-51"},"rs5112:rs5112;rs7246100:rs7246100:rs7254133",50]
["ENSG00000125755","SYMPK",19,46318668,46366548,-1,"protein_coding",8189,"SYMPK",0.997278492187137,-0.384639791,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000170608","FOXA3",19,46367247,46377055,1,"protein_coding",3171,"FOXA3",0.395510308295114,-0.452953673,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000176182","MYPOP",19,46393278,46405862,-1,"protein_coding",339344,"MYPOP",0.810391050855017,-0.668694835,0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":4.9E-9,"d":"4.90E-09"},"rs181765708",50]
["ENSG00000230510","PPP5D1",19,46984053,47104457,-1,"protein_coding",100506012,"PPP5D1",0.0393450229909042,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000268423","AC011551.3",19,47050313,47104118,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000160014","CALM3",19,47104331,47114050,1,"protein_coding",808,"CALM3",0.580172431977243,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000197380","DACT3",19,47150869,47164395,-1,"protein_coding",147906,"DACT3","NA",0.236210063,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":4.6e-12,"d":"4.60E-12"},"rs62120566;rs2965157",50]
["ENSG00000090372","STRN4",19,47222764,47250251,-1,"protein_coding",29888,"STRN4",0.999575131657329,-0.5987751,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":1.2e-35,"d":"1.20E-35"},"19:45531618_GT_G;rs149553138",50]
["ENSG00000130751","NPAS1",19,47523077,47549033,1,"protein_coding",4861,"NPAS1",0.916472527076156,"NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3e-06,"d":"3.00E-06"},"rs59774409",52]
["ENSG00000130748","TMEM160",19,47549165,47551888,-1,"protein_coding",54958,"TMEM160",0.654855932901688,-0.35853148,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":3e-06,"d":"3.00E-06"},"rs59774409",52]
["ENSG00000118160","SLC8A2",19,47931274,47975425,-1,"protein_coding",6543,"SLC8A2","NA",-0.264690994,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.6E-6,"d":"4.60E-06"},"rs35106244",51]
["ENSG00000088002","SULT2B1",19,49055332,49102682,1,"protein_coding",6820,"SULT2B1",0.827919001656143,0.006419371,0,0,1,{"v":3.37192e-05,"d":"3.37E-05"},{"v":7.35172e-19,"d":"7.35E-19"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":4.9e-07,"d":"4.90E-07"},"rs35106244",51]
["ENSG00000063177","RPL18",19,49118585,49122793,-1,"protein_coding",6141,"RPL18",0.554781180671353,-0.9363722,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.6E-6,"d":"4.60E-06"},"rs35106244",51]
["ENSG00000063176","SPHK2",19,49122548,49133974,1,"protein_coding",56848,"SPHK2",{"v":8.66423863572204e-06,"d":"8.66E-06"},-1.641176237,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":4.6E-6,"d":"4.60E-06"},"rs35106244",51]
["ENSG00000142233","NTN5",19,49164664,49176338,-1,"protein_coding",126147,"NTN5",{"v":3.27017246498834e-06,"d":"3.27E-06"},-0.402192771,2,2.777,33,{"v":4.34105e-06,"d":"4.34E-06"},0.000447775,"GTEx/v8/Artery_Tibial:GTEx/v8/Pancreas","+","No","NA",{"v":9.4e-09,"d":"9.40E-09"},"rs35106244",51]
["ENSG00000176920","FUT2",19,49199228,49209207,1,"protein_coding",2524,"FUT2",{"v":5.46581459214613e-12,"d":"5.47E-12"},4.200433008,38,52,38,{"v":2.64666e-63,"d":"2.65E-63"},{"v":1.45969e-53,"d":"1.46E-53"},"GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","-","No","NA",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000176909","MAMSTR",19,49215999,49222978,-1,"protein_coding",284358,"MAMSTR",1.23325809401916E-3,-0.052031801,38,52,38,{"v":6.2349e-18,"d":"6.23E-18"},{"v":2.98816e-20,"d":"2.99E-20"},"GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle","+","No","NA",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000105538","RASIP1",19,49223844,49243978,-1,"protein_coding",54922,"RASIP1",0.975494281851725,-0.599190215,3,13.01,29,{"v":4.54663e-06,"d":"4.55E-06"},{"v":7.9078e-05,"d":"7.91E-05"},"GTEx/v8/Artery_Aorta:GTEx/v8/Heart_Atrial_Appendage","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000182264","IZUMO1",19,49244109,49250166,-1,"protein_coding",284359,"IZUMO1",0.00241626337305742,0.753533326,0,0,24,{"v":8.76584e-06,"d":"8.77E-06"},{"v":9.97708e-19,"d":"9.98E-19"},"GTEx/v8/Heart_Atrial_Appendage","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000174951","FUT1",19,49251268,49258647,-1,"protein_coding",2523,"FUT1",0.000508774873537715,0.370474173,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000105550","FGF21",19,49258816,49261587,1,"protein_coding",26291,"FGF21",0.213002020207769,-0.215278159,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000105552","BCAT2",19,49298319,49314286,-1,"protein_coding",587,"BCAT2",{"v":1.71339042998067E-11,"d":"1.71E-11"},-0.850643193,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:hESC",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000087076","HSD17B14",19,49316274,49339935,-1,"protein_coding",51171,"HSD17B14",1.37252498082087E-3,0.796635241,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":4.6E-6,"d":"4.60E-06"},"rs35106244:rs59774409",2.161111111111111]
["ENSG00000087088","BAX",19,49458072,49465055,1,"protein_coding",581,"BAX",0.167938540925625,"NA",0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000087086","FTL",19,49468558,49470135,1,"protein_coding",2512,"FTL",0.000458652707063046,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000104812","GYS1",19,49471382,49496567,-1,"protein_coding",2997,"GYS1",0.00832267410134216,-0.427100909,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244:rs59774409",2.161111111111111]
["ENSG00000183207","RUVBL2",19,49496705,49519252,1,"protein_coding",10856,"RUVBL2",0.999110080217839,1.176884172,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244:rs59774409",2.161111111111111]
["ENSG00000104826","LHB",19,49519237,49520338,-1,"protein_coding",3972,"LHB",0.065600109491978,0.574913604,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244",51]
["ENSG00000267335","CTB-60B18.6",19,49526210,49540152,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244:rs59774409",2.161111111111111]
["ENSG00000104818","CGB2",19,49535169,49536495,1,"protein_coding",114336,"CGB2",0.0694219778865575,0.025765237,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":6.5e-09,"d":"6.50E-09"},"rs35106244:rs59774409",2.161111111111111]
["ENSG00000221916","C19orf73",19,49621655,49622397,-1,"protein_coding",55150,"C19orf73",0.48401312075747,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000177380","PPFIA3",19,49622646,49654283,1,"protein_coding",8541,"PPFIA3",0.99999959495107,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000063127","SLC6A16",19,49792895,49828482,-1,"protein_coding",28968,"SLC6A16",{"v":4.47639511693954e-11,"d":"4.48E-11"},-0.803886516,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000104872","PIH1D1",19,49949555,49956754,-1,"protein_coding",55011,"PIH1D1",0.087951252701366,0.323376102,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000161618","ALDH16A1",19,49956426,49974305,1,"protein_coding",126133,"ALDH16A1",{"v":1.35194745543971e-07,"d":"1.35E-07"},0.132278749,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000142541","RPL13A",19,49990811,49995565,1,"protein_coding",23521,"RPL13A",0.633828368843267,0.703415176,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000142534","RPS11",19,49999622,50002946,1,"protein_coding",6205,"RPS11",0.913344861476602,-0.285364057,0,0,107,{"v":1.68917E-10,"d":"1.69E-10"},{"v":1.11567E-23,"d":"1.12E-23"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Promoter_anchored_loops:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":5.3e-09,"d":"5.30E-09"},"rs59774409;rs35106244:rs59774409",2.161111111111111]
["ENSG00000268000","hsa-mir-150",19,50003781,50004614,1,"protein_coding","NA","NA","NA","NA",1,0.345,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":3.5e-08,"d":"3.50E-08"},"rs59774409;rs35106244:rs59774409",2.161111111111111]
["ENSG00000104870","FCGRT",19,50010073,50029590,1,"protein_coding",2217,"FCGRT",0.825587179671645,-0.630530045,52,11.58,107,{"v":9.5205e-17,"d":"9.52E-17"},{"v":2.30313e-12,"d":"2.30E-12"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Liver","-","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":5.3e-09,"d":"5.30E-09"},"rs59774409;rs35106244:rs59774409",2.161111111111111]
["ENSG00000142552","RCN3",19,50030875,50050219,1,"protein_coding",57333,"RCN3",{"v":1.77726445447237E-9,"d":"1.78E-09"},-0.511517783,115,25.3,107,{"v":1.56035e-31,"d":"1.56E-31"},{"v":1.2424e-25,"d":"1.24E-25"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":5.3e-09,"d":"5.30E-09"},"rs59774409",52]
["ENSG00000142546","NOSIP",19,50058968,50093519,-1,"protein_coding",51070,"NOSIP",0.00230156568092138,-0.458734704,12,8.226,0,"NA","NA","NA","NA","No","NA",{"v":3e-06,"d":"3.00E-06"},"rs59774409",52]
["ENSG00000126458","RRAS",19,50138549,50143458,-1,"protein_coding",6237,"RRAS",0.287257428796457,-0.530932413,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":3e-06,"d":"3.00E-06"},"rs59774409:rs35106244",2.161111111111111]
["ENSG00000126461","SCAF1",19,50145382,50161899,1,"protein_coding",58506,"SCAF1",0.998787538768532,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":3e-06,"d":"3.00E-06"},"rs59774409:rs35106244",2.161111111111111]
["ENSG00000126457","PRMT1",19,50179043,50192286,1,"protein_coding",3276,"PRMT1",0.993587786937211,-0.276977945,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000169169","CPT1C",19,50194155,50216988,1,"protein_coding",126129,"CPT1C",0.0002846277169503,-0.155830562,0,0,5,{"v":2.63762E-5,"d":"2.64E-05"},{"v":5.93031e-08,"d":"5.93E-08"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":1.4E-5,"d":"1.40E-05"},"rs59774409",52]
["ENSG00000126467","TSKS",19,50243010,50266587,-1,"protein_coding",60385,"TSKS",0.980813772290248,-0.204731972,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000196961","AP2A1",19,50270225,50310370,1,"protein_coding",160,"AP2A1",0.9998472799622,"NA",0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000039650","PNKP",19,50364461,50371166,-1,"protein_coding",11284,"PNKP",{"v":2.8844490761323e-07,"d":"2.88E-07"},0.180578716,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":7.2e-06,"d":"7.20E-06"},"rs59774409",52]
["ENSG00000198646","NCOA6",20,33284722,33413452,-1,"protein_coding",23054,"NCOA6",0.990815417122809,-0.852306051,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000078804","TP53INP2",20,33292094,33301243,1,"protein_coding",58476,"TP53INP2",0.341454389532318,-2.209102226,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000131067","GGT7",20,33432523,33460663,-1,"protein_coding",2686,"GGT7",0.998200259468736,-0.466160926,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000131069","ACSS2",20,33459949,33515769,1,"protein_coding",55902,"ACSS2",{"v":8.97239307211796e-11,"d":"8.97E-11"},-0.504093957,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":6.9e-08,"d":"6.90E-08"},"rs2378390",53]
["ENSG00000078814","MYH7B",20,33563206,33590240,1,"protein_coding",57644,"MYH7B",{"v":1.33080887914663E-23,"d":"1.33E-23"},0.056785336,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000100991","TRPC4AP",20,33590207,33680674,-1,"protein_coding",26133,"TRPC4AP",0.999538656142253,0.007918921,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.4e-06,"d":"2.40E-06"},"rs2378390",53]
["ENSG00000088298","EDEM2",20,33703167,33865928,-1,"protein_coding",55741,"EDEM2",0.000137533138342907,-0.173488786,0,0,41,{"v":5.093e-06,"d":"5.09E-06"},{"v":1.1604e-15,"d":"1.16E-15"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","IMR90",{"v":1.5e-08,"d":"1.50E-08"},"rs2378390",53]
["ENSG00000101000","PROCR",20,33759876,33765165,1,"protein_coding",10544,"PROCR",0.0101308888898987,-0.393625919,0,0,33,{"v":9.4446e-05,"d":"9.44E-05"},{"v":2.24902e-25,"d":"2.25E-25"},"GTEx/v8/Adipose_Subcutaneous","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-08,"d":"2.50E-08"},"rs2378390",53]
["ENSG00000125966","MMP24",20,33814457,33864801,1,"protein_coding",10893,"MMP24",0.0287623289506785,-0.485751474,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000242372","EIF6",20,33866714,33872788,-1,"protein_coding",3692,"EIF6",0.781942924365479,-0.028008437,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000125998","FAM83C",20,33873534,33880204,-1,"protein_coding",128876,"FAM83C",{"v":3.49242479222024E-5,"d":"3.49E-05"},0.230701112,0,0,0,"NA","NA","NA","NA","Yes","Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.4e-06,"d":"2.40E-06"},"rs2378390",53]
["ENSG00000101019","UQCC1",20,33890369,33999944,-1,"protein_coding",55245,"UQCC1",0.00485442531990324,-0.818063366,0,0,19,{"v":2.58274e-05,"d":"2.58E-05"},{"v":2.28438e-19,"d":"2.28E-19"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":3.5e-08,"d":"3.50E-08"},"rs2378390",53]
["ENSG00000125965","GDF5",20,34021145,34042568,-1,"protein_coding",8200,"GDF5",0.923194898928876,0.072736153,2,5.975,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000126001","CEP250",20,34042985,34099804,1,"protein_coding",11190,"CEP250",{"v":8.25125524749097e-17,"d":"8.25E-17"},-0.898375889,14,15.49,2,{"v":2.21568e-07,"d":"2.22E-07"},{"v":1.15239e-08,"d":"1.15E-08"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","-","Yes","Adult_Cortex:Fetal_Cortex:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000125975","C20orf173",20,34111014,34117481,-1,"protein_coding",140873,"C20orf173","NA",-0.017046168,22,7.783,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1.5e-08,"d":"1.50E-08"},"rs2378390",53]
["ENSG00000125991","ERGIC3",20,34129770,34145405,1,"protein_coding",51614,"ERGIC3",0.0038590767192969,-0.537742885,36,11.27,55,{"v":1.25435e-05,"d":"1.25E-05"},0.00650288,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum","+","Yes","Adult_Cortex:Fetal_Cortex",{"v":1E-8,"d":"1.00E-08"},"rs2378390",53]
["ENSG00000061656","SPAG4",20,34203814,34208971,1,"protein_coding",6676,"SPAG4",0.110567923366472,-0.441954464,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000214078","CPNE1",20,34213953,34252878,-1,"protein_coding",8904,"CPNE1",{"v":3.87095095726686e-07,"d":"3.87E-07"},"NA",0,0,56,{"v":2.57501e-71,"d":"2.58E-71"},{"v":6.32869e-144,"d":"6.33E-144"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Liver:GTEx/v8/Pancreas","+","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000272897","RP1-309K20.6",20,34220262,34262466,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000244462","RBM12",20,34236847,34252878,-1,"protein_coding",10137,"RBM12",0.474673920574839,-0.297433929,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000244005","NFS1",20,34255977,34287281,-1,"protein_coding",9054,"NFS1",0.832120909457389,-0.782190672,0,0,1,1.15992E-4,0.0344117,"GTEx/v8/Heart_Left_Ventricle","-","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000125995","ROMO1",20,34287194,34288906,1,"protein_coding",140823,"ROMO1",0.726806954057013,-0.303915371,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Left_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Trophoblast-like_Cell",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000131051","RBM39",20,34291531,34330234,-1,"protein_coding",9584,"RBM39",0.9999969154952,-0.857805175,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":6.9e-08,"d":"6.90E-08"},"rs2378390",53]
["ENSG00000025293","PHF20",20,34359896,34538303,1,"protein_coding",51230,"PHF20",0.975739227580779,-0.31477599,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex:Mesenchymal_Stem_Cell",{"v":6.9e-08,"d":"6.90E-08"},"rs2378390",53]
["ENSG00000171222","SCAND1",20,34541539,34547394,-1,"protein_coding",51282,"SCAND1",0.158311342081053,-1.080083136,0,0,1,{"v":1.33542e-08,"d":"1.34E-08"},{"v":4.83704e-16,"d":"4.84E-16"},"GTEx/v8/Artery_Aorta","-","Yes","Adult_Cortex:Fetal_Cortex:Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1E-8,"d":"1.00E-08"},"rs2378390",53]
["ENSG00000149646","CNBD2",20,34556512,34618622,1,"protein_coding",140894,"CNBD2",{"v":2.29296795546672e-07,"d":"2.29E-07"},-0.003103386,0,0,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":1.4E-8,"d":"1.40E-08"},"rs2378390",53]
["ENSG00000088367","EPB41L1",20,34679426,34820721,1,"protein_coding",2036,"EPB41L1",0.645386132721516,-0.629643623,0,0,1,{"v":5.84572e-06,"d":"5.85E-06"},{"v":1.69076E-23,"d":"1.69E-23"},"GTEx/v8/Artery_Tibial","-","Yes","Left_Ventricle",{"v":7.4e-07,"d":"7.40E-07"},"rs2378390",53]
["ENSG00000269650","AL121895.1",20,34756461,34758180,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm",{"v":3.2e-06,"d":"3.20E-06"},"rs2378390",53]
["ENSG00000101084","C20orf24",20,35234137,35240960,1,"protein_coding",55969,"C20orf24",0.856745481043852,"NA",0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs2378390",53]
["ENSG00000101342","TLDC2",20,35504524,35522638,1,"protein_coding",140711,"TLDC2",0.113178686310675,-0.852968274,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":6.9e-08,"d":"6.90E-08"},"rs2378390",53]
["ENSG00000170471","RALGAPB",20,37101459,37207504,1,"protein_coding",57148,"RALGAPB",0.999999955632558,-1.599770985,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.8e-08,"d":"2.80E-08"},"rs2179372;rs6129762",55]
["ENSG00000101442","ACTR5",20,37377085,37400834,1,"protein_coding",79913,"ACTR5",{"v":1.00014232070039E-12,"d":"1.00E-12"},0.539172179,0,0,0,"NA","NA","NA","NA","Yes","Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":5.5e-13,"d":"5.50E-13"},"rs2179372;rs6129762:rs2179372:rs1883711",2.288194444444444]
["ENSG00000101452","DHX35",20,37590942,37668366,1,"protein_coding",60625,"DHX35",{"v":9.69273790916275e-11,"d":"9.69E-11"},-0.629421294,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762:rs2179372:rs6129762",55]
["ENSG00000204103","MAFB",20,39314488,39317880,-1,"protein_coding",9935,"MAFB","NA",-1.167100522,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle:Liver:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":7.1e-15,"d":"7.10E-15"},"rs1883711:rs2179372;rs6129762:rs2179372",2.288194444444444]
["ENSG00000198900","TOP1",20,39657458,39753127,1,"protein_coding",7150,"TOP1",0.999999399962319,-1.244368761,14,6.727,0,"NA","NA","NA","NA","Yes","Aorta:Left_Ventricle:Liver:Right_Ventricle:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Neural_Progenitor_Cell:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762;rs6129762:rs2179372:rs6129762",55]
["ENSG00000124181","PLCG1",20,39765600,39811629,1,"protein_coding",5335,"PLCG1",0.76335235197211,"NA",15,22.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Hippocampus:Left_Ventricle:Liver:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762;rs6129762:rs2179372",55]
["ENSG00000174306","ZHX3",20,39807088,39946312,-1,"protein_coding",23051,"ZHX3",0.354421202947907,-2.86061457,63,22.9,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:Fetal_Cortex:Aorta:Hippocampus:Left_Ventricle:Liver:Right_Ventricle:Spleen:GM12878:IMR90:Mesenchymal_Stem_Cell:Mesendoderm:Trophoblast-like_Cell:hESC",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762;rs6129762:rs2179372:rs6129762",55]
["ENSG00000132793","LPIN3",20,39969560,39989222,1,"protein_coding",64900,"LPIN3",{"v":4.43532236084843e-11,"d":"4.44E-11"},1.280780073,1,3.264,80,{"v":6.72024e-18,"d":"6.72E-18"},{"v":1.60147e-33,"d":"1.60E-33"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Pancreas","+","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762;rs6129762:rs6129762:rs2179372",55]
["ENSG00000183798","EMILIN3",20,39988606,39995467,-1,"protein_coding",90187,"EMILIN3",0.00139809720973059,0.56095672,0,0,76,{"v":3.02111E-6,"d":"3.02E-06"},{"v":7.35136E-5,"d":"7.35E-05"},"GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Liver","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762;rs6129762:rs6129762:rs2179372",55]
["ENSG00000124177","CHD6",20,40030741,40247133,-1,"protein_coding",84181,"CHD6",0.99999999999754,-0.875165314,0,0,0,"NA","NA","NA","NA","Yes","Fetal_Cortex",{"v":2.7E-8,"d":"2.70E-08"},"rs2179372;rs6129762",55]
["ENSG00000196090","PTPRT",20,40701392,41818610,-1,"protein_coding",11122,"PTPRT",0.999998893194682,2.656289086,0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":3.3e-09,"d":"3.30E-09"},"rs2179372;rs6129762:rs6129762:rs2179372",55]
["ENSG00000124193","SRSF6",20,42086568,42092245,1,"protein_coding",6431,"SRSF6",0.992976413171211,-0.317719212,0,0,0,"NA","NA","NA","NA","Yes","IMR90:Mesendoderm",{"v":3.3e-09,"d":"3.30E-09"},"rs2179372;rs6129762:rs6129762:rs2179372",55]
["ENSG00000185513","L3MBTL1",20,42136320,42179590,1,"protein_coding",26013,"L3MBTL1",{"v":2.0785493269036e-07,"d":"2.08E-07"},"NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell:Mesendoderm",{"v":2.8e-08,"d":"2.80E-08"},"rs2179372;rs6129762",55]
["ENSG00000101049","SGK2",20,42187608,42216877,1,"protein_coding",10110,"SGK2",{"v":2.93457296557479e-07,"d":"2.93E-07"},0.613864962,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":2.5e-09,"d":"2.50E-09"},"rs2179372;rs6129762:rs2179372",55]
["ENSG00000124194","GDAP1L1",20,42875887,42909013,1,"protein_coding",78997,"GDAP1L1",0.353968502367603,-0.354242621,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":2.6e-10,"d":"2.60E-10"},"rs1800961",56]
["ENSG00000101076","HNF4A",20,42984340,43061485,1,"protein_coding",3172,"HNF4A",0.919225678145736,-0.204329418,1,22.3,0,"NA","NA","NA","NA","No","NA",{"v":2.6e-10,"d":"2.60E-10"},"rs1800961",56]
["ENSG00000269605","Z97053.1",20,43234346,43248126,-1,"protein_coding","NA","NA","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Mesenchymal_Stem_Cell",{"v":2.6e-10,"d":"2.60E-10"},"rs1800961",56]
["ENSG00000183773","AIFM3",22,21319396,21335649,1,"protein_coding",150209,"AIFM3",{"v":1.95828310839448e-10,"d":"1.96E-10"},"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_links_oneway:IMR90",{"v":5.6e-09,"d":"5.60E-09"},"rs5754102",57]
["ENSG00000099949","LZTR1",22,21333751,21353327,1,"protein_coding",8216,"LZTR1",{"v":3.38323005538586e-52,"d":"3.38E-52"},-0.417759553,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":5.2e-09,"d":"5.20E-09"},"rs5754102",57]
["ENSG00000183246","RIMBP3C",22,21899646,21905750,-1,"protein_coding",150221,"RIMBP3C","NA",-0.653022692,3,6.529,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":5.9e-09,"d":"5.90E-09"},"rs5754102",57]
["ENSG00000185651","UBE2L3",22,21903736,21978323,1,"protein_coding",7332,"UBE2L3",0.778719690860565,"NA",107,23.9,85,{"v":6.15638e-08,"d":"6.16E-08"},0.000141069,"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage","-","Yes","Promoter_anchored_loops",{"v":2.1e-09,"d":"2.10E-09"},"rs5754102",57]
["ENSG00000161179","YDJC",22,21982378,21984353,-1,"protein_coding",150223,"YDJC",2.15046445208775E-3,-0.006438946,20,23.9,87,{"v":4.44029e-07,"d":"4.44E-07"},{"v":4.161e-15,"d":"4.16E-15"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Heart_Atrial_Appendage","-","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-09,"d":"4.40E-09"},"rs5754102",57]
["ENSG00000161180","CCDC116",22,21987005,21991616,1,"protein_coding",164592,"CCDC116",{"v":3.97673357670938e-05,"d":"3.98E-05"},-0.389172516,15,23.9,87,{"v":1.07941e-46,"d":"1.08E-46"},{"v":1.45678e-40,"d":"1.46E-40"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Coronary:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","Yes","IMR90:Mesenchymal_Stem_Cell",{"v":4.4e-09,"d":"4.40E-09"},"rs5754102",57]
["ENSG00000128228","SDF2L1",22,21996550,21998587,1,"protein_coding",23753,"SDF2L1",0.0542960896755155,-0.138940151,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":4.7e-09,"d":"4.70E-09"},"rs5754102",57]
["ENSG00000100023","PPIL2",22,22006559,22054304,1,"protein_coding",23759,"PPIL2",0.0274929870468308,-0.620763606,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:Fetal_Cortex",{"v":5.2e-09,"d":"5.20E-09"},"rs5754102",57]
["ENSG00000100034","PPM1F",22,22273793,22307209,-1,"protein_coding",9647,"PPM1F",0.000267470134913572,-1.051395101,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex",{"v":5.2e-09,"d":"5.20E-09"},"rs5754102",57]
["ENSG00000073150","PANX2",22,50609160,50618723,1,"protein_coding",56666,"PANX2",0.0149007665484345,0.796408959,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-05,"d":"1.00E-05"},"rs9616847",58]
["ENSG00000100429","HDAC10",22,50683612,50689834,-1,"protein_coding",83933,"HDAC10",{"v":3.2788087078515e-12,"d":"3.28E-12"},"NA",0,0,1,{"v":1.62995e-05,"d":"1.63E-05"},{"v":7.7937e-31,"d":"7.79E-31"},"GTEx/v8/Adipose_Subcutaneous","+","No","NA",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000196576","PLXNB2",22,50713408,50746056,-1,"protein_coding",23654,"PLXNB2",0.992862470603308,"NA",0,0,1,{"v":3.12276e-05,"d":"3.12E-05"},{"v":8.27871e-06,"d":"8.28E-06"},"GTEx/v8/Artery_Aorta","-","Yes","Promoter_anchored_loops",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000100239","PPP6R2",22,50781733,50883514,1,"protein_coding",9701,"PPP6R2",0.718789474101901,"NA",73,9.766,69,{"v":9.94469e-09,"d":"9.94E-09"},{"v":1.04154E-19,"d":"1.04E-19"},"GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial","+","Yes","Promoter_anchored_loops:Adult_Cortex",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000100241","SBF1",22,50883429,50913454,-1,"protein_coding",6305,"SBF1",0.690538813887376,"NA",5,5.902,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":3.4e-06,"d":"3.40E-06"},"rs9616847",58]
["ENSG00000128165","ADM2",22,50919985,50924869,1,"protein_coding",79924,"ADM2",0.0153000381093707,1.175329061,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000100253","MIOX",22,50925213,50929077,1,"protein_coding",55586,"MIOX",{"v":4.60477630861768e-12,"d":"4.60E-12"},0.468067493,0,0,0,"NA","NA","NA","NA","Yes","Adult_Cortex:IMR90:Mesenchymal_Stem_Cell",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000100258","LMF2",22,50941376,50946135,-1,"protein_coding",91289,"LMF2","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000025770","NCAPH2",22,50946645,50961901,1,"protein_coding",29781,"NCAPH2","NA","NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:IMR90:Mesenchymal_Stem_Cell",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000130489","SCO2",22,50961997,50964868,-1,"protein_coding",9997,"SCO2",1.01907145142781E-4,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000025708","TYMP",22,50964181,50968485,-1,"protein_coding",1890,"TYMP",0.000465858647806756,"NA",0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops:EP_correlation_cell_type_oneway",{"v":1E-8,"d":"1.00E-08"},"rs9616847",58]
["ENSG00000177989","ODF3B",22,50968139,50971009,-1,"protein_coding",440836,"ODF3B",9.16745822195973E-3,"NA",0,0,0,"NA","NA","NA","NA","Yes","EP_correlation_cell_type_oneway",{"v":1.1E-5,"d":"1.10E-05"},"rs9616847",58]
["ENSG00000079974","RABL2B",22,51205929,51222091,-1,"protein_coding",11158,"RABL2B",0.765589454248129,-0.430721455,0,0,0,"NA","NA","NA","NA","Yes","Promoter_anchored_loops",{"v":1e-05,"d":"1.00E-05"},"rs9616847",58]
["ENSG00000157600","TMEM164",23,109245859,109425962,1,"protein_coding",84187,"TMEM164",0.877400449225457,-2.007872381,0,0,0,"NA","NA","NA","NA","Yes","IMR90",{"v":1.5E-10,"d":"1.50E-10"},"rs372038686",59]
["ENSG00000101935","AMMECR1",23,109437414,109683461,-1,"protein_coding",9949,"AMMECR1",0.910792997313756,-2.109243506,7,13.98,0,"NA","NA","NA","NA","Yes","Mesendoderm:hESC",{"v":1.5E-10,"d":"1.50E-10"},"rs372038686",59]
["ENSG00000243978","RGAG1",23,109602044,109699562,1,"protein_coding",57529,"RGAG1",0.912655333274139,0.494918933,22,13.98,376,{"v":3.01409e-06,"d":"3.01E-06"},0.00335742,"GTEx/v8/Heart_Atrial_Appendage","-","No","NA",{"v":1.3e-10,"d":"1.30E-10"},"rs372038686",59]
["ENSG00000101938","CHRDL1",23,109917084,110039286,-1,"protein_coding",91851,"CHRDL1",0.0536284936083553,"NA",77,16.15,392,{"v":7.97604e-50,"d":"7.98E-50"},{"v":1.32344E-42,"d":"1.32E-42"},"GTEx/v8/Adipose_Subcutaneous:GTEx/v8/Adipose_Visceral_Omentum:GTEx/v8/Artery_Aorta:GTEx/v8/Artery_Tibial:GTEx/v8/Heart_Atrial_Appendage:GTEx/v8/Heart_Left_Ventricle:GTEx/v8/Pancreas","+","No","NA",{"v":1.3e-10,"d":"1.30E-10"},"rs372038686",59]
["ENSG00000077279","DCX",23,110537007,110655603,-1,"protein_coding",1641,"DCX",0.863196407367064,-3.566269335,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.3e-08,"d":"1.30E-08"},"rs372038686",59]
["ENSG00000187823","ZCCHC16",23,111697727,111700473,1,"protein_coding",340595,"ZCCHC16",0.000561724706329207,1.180700486,0,0,0,"NA","NA","NA","NA","Yes","Left_Ventricle",{"v":1.5E-10,"d":"1.50E-10"},"rs372038686",59]

{"sheet":"ST5A","index":8,"n_rows":53,"n_cols":7,"rows_kept":53}
["Gene Set","N genes","Beta","Beta STD","SE","P","Pbon"]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_remodeling",13,3.2261,0.083088,0.28572,{"v":9.1447e-30,"d":"9.14E-30"},{"v":1.416331136e-25,"d":"1.42E-25"}]
["GO_bp:go_reverse_cholesterol_transport",17,2.7504,0.080998,0.24439,{"v":1.3896e-29,"d":"1.39E-29"},{"v":2.15207352e-25,"d":"2.15E-25"}]
["GO_bp:go_very_low_density_lipoprotein_particle_remodeling",11,3.3731,0.079917,0.30826,{"v":4.433e-28,"d":"4.43E-28"},{"v":6.8649438e-24,"d":"6.86E-24"}]
["GO_bp:go_high_density_lipoprotein_particle_remodeling",17,2.3272,0.068535,0.22937,{"v":2.0073e-24,"d":"2.01E-24"},{"v":3.10830405e-20,"d":"3.11E-20"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_remodeling",32,1.599,0.064582,0.17193,{"v":7.7836e-21,"d":"7.78E-21"},{"v":1.205212624E-16,"d":"1.21E-16"}]
["Curated_gene_sets:reactome_hdl_remodeling",10,2.6248,0.059296,0.28833,{"v":4.8296e-20,"d":"4.83E-20"},{"v":7.47766968e-16,"d":"7.48E-16"}]
["GO_bp:go_protein_containing_complex_remodeling",30,1.5699,0.061396,0.17691,{"v":3.8569e-19,"d":"3.86E-19"},{"v":5.97125258e-15,"d":"5.97E-15"}]
["GO_mf:go_apolipoprotein_a_i_binding",5,3.9091,0.062452,0.45646,{"v":5.8885e-18,"d":"5.89E-18"},{"v":9.11598685e-14,"d":"9.12E-14"}]
["GO_cc:go_protein_lipid_complex",40,1.1315,0.051081,0.14009,{"v":3.5338e-16,"d":"3.53E-16"},{"v":5.4703224e-12,"d":"5.47E-12"}]
["Curated_gene_sets:reactome_chylomicron_clearance",5,3.3396,0.053354,0.41717,{"v":6.3154E-16,"d":"6.32E-16"},{"v":9.77560766e-12,"d":"9.78E-12"}]
["GO_cc:go_high_density_lipoprotein_particle",27,1.4197,0.052676,0.17767,{"v":7.1318e-16,"d":"7.13E-16"},{"v":1.103860004E-11,"d":"1.10E-11"}]
["GO_bp:go_protein_lipid_complex_subunit_organization",50,1.0662,0.053802,0.13421,{"v":1.0362E-15,"d":"1.04E-15"},{"v":1.60372674E-11,"d":"1.60E-11"}]
["GO_mf:go_apolipoprotein_binding",17,1.9327,0.056916,0.24392,{"v":1.2234e-15,"d":"1.22E-15"},{"v":1.89333384e-11,"d":"1.89E-11"}]
["GO_bp:go_lipid_homeostasis",128,0.60884,0.049059,0.077734,{"v":2.5284e-15,"d":"2.53E-15"},{"v":3.912699e-11,"d":"3.91E-11"}]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_clearance",9,2.6188,0.056126,0.33552,{"v":3.1319e-15,"d":"3.13E-15"},{"v":4.84630206e-11,"d":"4.85E-11"}]
["GO_bp:go_sterol_homeostasis",78,0.78027,0.049143,0.10207,{"v":1.1E-14,"d":"1.10E-14"},{"v":1.70203e-10,"d":"1.70E-10"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly_remodeling_and_clearance",71,0.79939,0.048044,0.10484,{"v":1.2838e-14,"d":"1.28E-14"},{"v":1.98629536e-10,"d":"1.99E-10"}]
["GO_bp:go_regulation_of_plasma_lipoprotein_particle_levels",86,0.72126,0.047689,0.095659,{"v":2.4642e-14,"d":"2.46E-14"},{"v":3.81236382e-10,"d":"3.81E-10"}]
["GO_bp:go_protein_lipid_complex_assembly",32,1.1319,0.045715,0.16857,{"v":9.7059e-12,"d":"9.71E-12"},{"v":1.50150273e-07,"d":"1.50E-07"}]
["GO_bp:go_acylglycerol_homeostasis",33,0.98678,0.040471,0.14721,{"v":1.0501E-11,"d":"1.05E-11"},{"v":1.62439969e-07,"d":"1.62E-07"}]
["GO_bp:go_plasma_lipoprotein_particle_clearance",54,0.74464,0.039046,0.11786,{"v":1.3582E-10,"d":"1.36E-10"},{"v":2.10086376e-06,"d":"2.10E-06"}]
["GO_bp:go_steroid_esterification",14,1.5336,0.040988,0.24334,{"v":1.5015e-10,"d":"1.50E-10"},{"v":2.32237005E-6,"d":"2.32E-06"}]
["GO_cc:go_intermediate_density_lipoprotein_particle",5,3.224,0.051506,0.51375,{"v":1.7841e-10,"d":"1.78E-10"},{"v":2.75928906e-06,"d":"2.76E-06"}]
["GO_bp:go_secondary_alcohol_metabolic_process",85,0.57848,0.038027,0.093155,{"v":2.7109e-10,"d":"2.71E-10"},{"v":4.19240685e-06,"d":"4.19E-06"}]
["GO_bp:go_neutral_lipid_metabolic_process",119,0.53479,0.04156,0.087242,{"v":4.4866e-10,"d":"4.49E-10"},{"v":6.93807824e-06,"d":"6.94E-06"}]
["GO_bp:go_neutral_lipid_catabolic_process",40,0.96924,0.043758,0.16021,{"v":7.3988e-10,"d":"7.40E-10"},{"v":1.144076444E-5,"d":"1.14E-05"}]
["GO_bp:go_glycerolipid_catabolic_process",61,0.76859,0.042827,0.12774,{"v":9.0602e-10,"d":"9.06E-10"},{"v":1.400888124E-5,"d":"1.40E-05"}]
["GO_bp:go_chylomicron_remodeling",9,2.1987,0.047122,0.37017,{"v":1.4538e-09,"d":"1.45E-09"},{"v":2.24772018e-05,"d":"2.25E-05"}]
["GO_bp:go_sterol_transport",94,0.58126,0.040172,0.098556,{"v":1.8759e-09,"d":"1.88E-09"},{"v":2.9001414e-05,"d":"2.90E-05"}]
["GO_mf:go_protein_lipid_complex_binding",28,1.1638,0.043971,0.19736,{"v":1.8874e-09,"d":"1.89E-09"},{"v":2.91773166e-05,"d":"2.92E-05"}]
["Curated_gene_sets:reactome_chylomicron_remodeling",10,2.0156,0.045533,0.34502,{"v":2.6254e-09,"d":"2.63E-09"},{"v":4.05834332e-05,"d":"4.06E-05"}]
["GO_bp:go_high_density_lipoprotein_particle_assembly",15,1.2829,0.035489,0.21976,{"v":2.6952E-9,"d":"2.70E-09"},{"v":4.16597064E-5,"d":"4.17E-05"}]
["GO_bp:go_high_density_lipoprotein_particle_clearance",13,1.4259,0.036724,0.24601,{"v":3.4529e-09,"d":"3.45E-09"},{"v":5.33680224e-05,"d":"5.34E-05"}]
["GO_bp:go_sterol_metabolic_process",96,0.51779,0.036163,0.090238,{"v":4.8677e-09,"d":"4.87E-09"},{"v":7.52303035e-05,"d":"7.52E-05"}]
["GO_bp:go_triglyceride_catabolic_process",33,1.0422,0.042745,0.18194,{"v":5.1508E-9,"d":"5.15E-09"},{"v":7.96004632E-5,"d":"7.96E-05"}]
["GO_bp:go_phospholipid_homeostasis",10,1.6547,0.037382,0.30362,{"v":2.5512E-8,"d":"2.55E-08"},0.000394236936]
["GO_bp:go_steroid_metabolic_process",303,0.27112,0.03346,0.051983,{"v":9.2713e-08,"d":"9.27E-08"},0.001432601276]
["GO_bp:go_acylglycerol_metabolic_process",60,0.61877,0.034196,0.11955,{"v":1.1455E-7,"d":"1.15E-07"},1.76991205E-3]
["GO_bp:go_chylomicron_assembly",10,1.8019,0.040706,0.35171,{"v":1.5182e-07,"d":"1.52E-07"},0.002345619]
["GO_bp:go_lipoprotein_metabolic_process",30,0.91453,0.035766,0.18216,{"v":2.603e-07,"d":"2.60E-07"},0.0040213747]
["GO_mf:go_o_acyltransferase_activity",47,0.68492,0.033513,0.14025,{"v":5.2528e-07,"d":"5.25E-07"},0.00811452544]
["GO_bp:go_regulation_of_lipoprotein_lipase_activity",21,1.0575,0.03461,0.21855,{"v":6.5891e-07,"d":"6.59E-07"},0.01017818277]
["Curated_gene_sets:nikolsky_breast_cancer_11q12_q14_amplicon",155,0.56426,0.049998,0.11846,{"v":9.6002e-07,"d":"9.60E-07"},0.01482846892]
["GO_bp:go_cholesterol_efflux",41,0.66765,0.030516,0.14058,{"v":1.0281e-06,"d":"1.03E-06"},0.0158790045]
["GO_cc:go_triglyceride_rich_plasma_lipoprotein_particle",20,1.0264,0.032784,0.21685,{"v":1.1128E-6,"d":"1.11E-06"},0.0171860832]
["Curated_gene_sets:reactome_plasma_lipoprotein_clearance",33,0.66492,0.027271,0.14074,{"v":1.1615E-6,"d":"1.16E-06"},0.0179370445]
["GO_cc:go_clathrin_coated_endocytic_vesicle_membrane",41,0.68664,0.031383,0.14793,{"v":1.74e-06,"d":"1.74E-06"},0.02686908]
["GO_bp:go_positive_regulation_of_cholesterol_storage",7,1.8779,0.035496,0.4046,{"v":1.7428e-06,"d":"1.74E-06"},0.0269105748]
["GO_bp:go_phospholipid_catabolic_process",38,0.69328,0.030508,0.14987,{"v":1.8781e-06,"d":"1.88E-06"},0.028997864]
["GO_bp:go_triglyceride_metabolic_process",41,0.65802,0.030076,0.14333,{"v":2.2213e-06,"d":"2.22E-06"},0.0342946507]
["Curated_gene_sets:reactome_synthesis_of_16_20_hydroxyeicosatetraenoic_acids_hete",9,1.3859,0.029703,0.30316,{"v":2.4372e-06,"d":"2.44E-06"},0.0376254936]
["GO_bp:go_omega_hydroxylase_p450_pathway",9,1.3859,0.029703,0.30316,{"v":2.4372e-06,"d":"2.44E-06"},0.0376254936]

{"sheet":"ST5B","index":9,"n_rows":65,"n_cols":7,"rows_kept":65}
["Gene Set","N genes","Beta","Beta STD","SE","P","Pbon"]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_remodeling",13,2.9107,0.074489,0.30097,{"v":2.2621e-22,"d":"2.26E-22"},{"v":3.50354048e-18,"d":"3.50E-18"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_remodeling",32,1.6856,0.067648,0.18078,{"v":6.2212e-21,"d":"6.22E-21"},{"v":9.63477244e-17,"d":"9.63E-17"}]
["GO_bp:go_very_low_density_lipoprotein_particle_remodeling",11,2.9669,0.069847,0.32624,{"v":5.2353e-20,"d":"5.24E-20"},{"v":8.10738558e-16,"d":"8.11E-16"}]
["GO_bp:go_reverse_cholesterol_transport",17,2.2276,0.065186,0.25772,{"v":2.9406E-18,"d":"2.94E-18"},{"v":4.5535191e-14,"d":"4.55E-14"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly_remodeling_and_clearance",71,0.92417,0.055192,0.1082,{"v":7.1273e-18,"d":"7.13E-18"},{"v":1.103591132E-13,"d":"1.10E-13"}]
["GO_bp:go_regulation_of_lipoprotein_lipase_activity",21,1.7918,0.058268,0.22436,{"v":7.3767e-16,"d":"7.38E-16"},{"v":1.142134461E-11,"d":"1.14E-11"}]
["Curated_gene_sets:reactome_chylomicron_remodeling",10,2.8775,0.064591,0.36826,{"v":2.9248e-15,"d":"2.92E-15"},{"v":4.52817536e-11,"d":"4.53E-11"}]
["GO_bp:go_protein_containing_complex_remodeling",30,1.429,0.055533,0.18687,{"v":1.0776E-14,"d":"1.08E-14"},{"v":1.66823256e-10,"d":"1.67E-10"}]
["GO_cc:go_protein_lipid_complex",40,1.163,0.052174,0.15243,{"v":1.2328E-14,"d":"1.23E-14"},{"v":1.9083744e-10,"d":"1.91E-10"}]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_clearance",9,2.8084,0.059807,0.36986,{"v":1.6369e-14,"d":"1.64E-14"},{"v":2.53375751e-10,"d":"2.53E-10"}]
["Curated_gene_sets:reactome_assembly_of_active_lpl_and_lipc_lipase_complexes",19,1.7855,0.055232,0.24298,{"v":1.047E-13,"d":"1.05E-13"},{"v":1.6205466e-09,"d":"1.62E-09"}]
["GO_bp:go_sterol_homeostasis",78,0.82509,0.051637,0.11311,{"v":1.5562E-13,"d":"1.56E-13"},{"v":2.40853074e-09,"d":"2.41E-09"}]
["GO_cc:go_high_density_lipoprotein_particle",27,1.3612,0.050185,0.18993,{"v":3.9822e-13,"d":"3.98E-13"},{"v":6.16285272e-09,"d":"6.16E-09"}]
["GO_bp:go_regulation_of_plasma_lipoprotein_particle_levels",86,0.68901,0.045269,0.09655,{"v":4.9691e-13,"d":"4.97E-13"},{"v":7.68968225e-09,"d":"7.69E-09"}]
["GO_bp:go_protein_lipid_complex_subunit_organization",50,0.93093,0.04668,0.13076,{"v":5.6232e-13,"d":"5.62E-13"},{"v":8.70133968e-09,"d":"8.70E-09"}]
["GO_bp:go_high_density_lipoprotein_particle_remodeling",17,1.7058,0.049915,0.24342,{"v":1.2549E-12,"d":"1.25E-12"},{"v":1.94170677e-08,"d":"1.94E-08"}]
["GO_bp:go_chylomicron_remodeling",9,2.6915,0.057317,0.39582,{"v":5.3987e-12,"d":"5.40E-12"},{"v":8.35286864e-08,"d":"8.35E-08"}]
["GO_bp:go_neutral_lipid_catabolic_process",40,1.1234,0.050398,0.16576,{"v":6.3006E-12,"d":"6.30E-12"},{"v":9.74765826e-08,"d":"9.75E-08"}]
["GO_bp:go_acylglycerol_homeostasis",33,1.0471,0.042675,0.15885,{"v":2.2272e-11,"d":"2.23E-11"},{"v":3.4454784E-7,"d":"3.45E-07"}]
["GO_mf:go_apolipoprotein_binding",17,1.5937,0.046634,0.24615,{"v":4.8776e-11,"d":"4.88E-11"},{"v":7.54515944e-07,"d":"7.55E-07"}]
["GO_cc:go_chylomicron",13,1.818,0.046527,0.28123,{"v":5.2075e-11,"d":"5.21E-11"},{"v":8.054961e-07,"d":"8.05E-07"}]
["GO_bp:go_lipid_homeostasis",128,0.54603,0.043721,0.084517,{"v":5.3454e-11,"d":"5.35E-11"},{"v":8.26773018e-07,"d":"8.27E-07"}]
["GO_bp:go_glycerolipid_catabolic_process",61,0.82187,0.045507,0.13031,{"v":1.4526E-10,"d":"1.45E-10"},{"v":2.24659116e-06,"d":"2.25E-06"}]
["GO_bp:go_triglyceride_catabolic_process",33,1.1671,0.047565,0.18566,{"v":1.6604E-10,"d":"1.66E-10"},{"v":2.5678086e-06,"d":"2.57E-06"}]
["GO_bp:go_lipoprotein_metabolic_process",30,1.2271,0.047684,0.19534,{"v":1.7126e-10,"d":"1.71E-10"},{"v":2.64836464E-6,"d":"2.65E-06"}]
["Curated_gene_sets:reactome_chylomicron_clearance",5,3.0103,0.047787,0.48131,{"v":2.0408e-10,"d":"2.04E-10"},{"v":3.15568904e-06,"d":"3.16E-06"}]
["GO_bp:go_phospholipid_efflux",12,2.0534,0.050491,0.33395,{"v":3.9793e-10,"d":"3.98E-10"},{"v":6.15279366e-06,"d":"6.15E-06"}]
["GO_cc:go_triglyceride_rich_plasma_lipoprotein_particle",20,1.4043,0.04457,0.23348,{"v":9.1651e-10,"d":"9.17E-10"},{"v":1.417016111E-5,"d":"1.42E-05"}]
["GO_bp:go_plasma_lipoprotein_particle_clearance",54,0.73916,0.038514,0.12424,{"v":1.3678E-9,"d":"1.37E-09"},{"v":2.1146188e-05,"d":"2.11E-05"}]
["GO_bp:go_protein_lipid_complex_assembly",32,0.93737,0.037619,0.15802,{"v":1.5226e-09,"d":"1.52E-09"},{"v":2.35378734E-5,"d":"2.35E-05"}]
["Curated_gene_sets:hsiao_liver_specific_genes",247,0.35378,0.039231,0.061255,{"v":3.8975e-09,"d":"3.90E-09"},{"v":6.0247555e-05,"d":"6.02E-05"}]
["Curated_gene_sets:kegg_retinol_metabolism",64,0.84175,0.047736,0.14892,{"v":8.0259e-09,"d":"8.03E-09"},0.0001240563363]
["GO_bp:go_neutral_lipid_metabolic_process",119,0.49676,0.03836,0.08854,{"v":1.0229E-8,"d":"1.02E-08"},0.000158099424]
["GO_bp:go_sterol_transport",94,0.5579,0.038314,0.10159,{"v":2.0149e-08,"d":"2.01E-08"},0.000311402795]
["Curated_gene_sets:reactome_glucuronidation",26,1.6215,0.058665,0.29646,{"v":2.2881e-08,"d":"2.29E-08"},0.000353602974]
["GO_cc:go_intermediate_density_lipoprotein_particle",5,2.9119,0.046225,0.53929,{"v":3.3848E-8,"d":"3.38E-08"},0.000523053144]
["GO_bp:go_regulation_of_lipoprotein_metabolic_process",10,1.7371,0.038993,0.32776,{"v":5.8589e-08,"d":"5.86E-08"},0.000905317228]
["Curated_gene_sets:kegg_metabolism_of_xenobiotics_by_cytochrome_p450",70,0.72135,0.042776,0.13861,{"v":9.8381e-08,"d":"9.84E-08"},1.520084831E-3]
["GO_bp:go_monocarboxylic_acid_metabolic_process",463,0.23565,0.035579,0.045443,{"v":1.0883E-7,"d":"1.09E-07"},1.6814235E-3]
["Curated_gene_sets:kegg_drug_metabolism_cytochrome_p450",72,0.6948,0.041784,0.13503,{"v":1.3485e-07,"d":"1.35E-07"},2.08329765E-3]
["GO_mf:go_phosphatidylcholine_sterol_o_acyltransferase_activator_activity",6,1.9392,0.033722,0.37952,{"v":1.6298e-07,"d":"1.63E-07"},0.00251771504]
["GO_bp:go_high_density_lipoprotein_particle_assembly",15,1.104,0.030348,0.21638,{"v":1.6954e-07,"d":"1.70E-07"},0.00261888438]
["GO_bp:go_uronic_acid_metabolic_process",20,1.7803,0.056502,0.34932,{"v":1.7468E-7,"d":"1.75E-07"},0.00269810728]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly",19,1.1088,0.034301,0.21817,{"v":1.8817E-7,"d":"1.88E-07"},0.00290628565]
["GO_bp:go_phospholipid_homeostasis",10,1.6207,0.03638,0.32223,{"v":2.4802e-07,"d":"2.48E-07"},0.00383042088]
["GO_bp:go_cholesterol_storage",17,1.2339,0.036106,0.24554,{"v":2.5404e-07,"d":"2.54E-07"},0.00392313972]
["GO_bp:go_high_density_lipoprotein_particle_clearance",13,1.4186,0.036306,0.28505,{"v":3.2595e-07,"d":"3.26E-07"},0.0050333199]
["Curated_gene_sets:reactome_hdl_remodeling",10,1.5074,0.033838,0.30423,{"v":3.651e-07,"d":"3.65E-07"},0.0056375091]
["Curated_gene_sets:reactome_plasma_lipoprotein_clearance",33,0.73621,0.030003,0.15021,{"v":4.8018e-07,"d":"4.80E-07"},0.0074139792]
["GO_bp:go_regulation_of_sterol_transport",45,0.72839,0.034654,0.15074,{"v":6.8108e-07,"d":"6.81E-07"},0.01051519412]
["GO_bp:go_steroid_metabolic_process",304,0.26433,0.032472,0.054751,{"v":6.9547e-07,"d":"6.95E-07"},0.01073666586]
["GO_bp:go_cholesterol_efflux",41,0.68699,0.031201,0.14301,{"v":7.8495E-7,"d":"7.85E-07"},0.01211727315]
["GO_mf:go_ketosteroid_monooxygenase_activity",6,2.5216,0.043849,0.52677,{"v":8.5353e-07,"d":"8.54E-07"},0.01317508908]
["GO_bp:go_steroid_esterification",14,1.2211,0.032428,0.25568,{"v":9.0227e-07,"d":"9.02E-07"},0.01392653745]
["GO_bp:go_lipid_storage",67,0.5917,0.03433,0.12463,{"v":1.0373E-6,"d":"1.04E-06"},0.0160096882]
["GO_bp:go_secondary_alcohol_metabolic_process",85,0.47972,0.031335,0.10131,{"v":1.1025E-6,"d":"1.10E-06"},0.0170148825]
["Curated_gene_sets:nikolsky_breast_cancer_11q12_q14_amplicon",156,0.57773,0.051033,0.12236,{"v":1.1777E-6,"d":"1.18E-06"},0.0181742664]
["GO_bp:go_sterol_metabolic_process",96,0.46495,0.032267,0.098527,{"v":1.1933e-06,"d":"1.19E-06"},0.0184138123]
["GO_bp:go_organic_acid_metabolic_process",883,0.15116,0.031174,0.032557,{"v":1.7301E-6,"d":"1.73E-06"},0.026695443]
["GO_bp:go_intestinal_absorption",35,0.74643,0.031327,0.16213,{"v":2.0862E-6,"d":"2.09E-06"},0.0321879798]
["GO_mf:go_protein_lipid_complex_binding",28,0.95665,0.035917,0.21071,{"v":2.8303e-06,"d":"2.83E-06"},0.0436658684]
[]
["MAGMA gene-set analysis is performed for curated gene sets and GO terms obtained from MsigDB (see details: https://fuma.ctglab.nl/tutorial#magma).\n"]
["The table displays significant gene sets with Pbon < 0.05 using the full distribution of SNP p-values."]

{"sheet":"ST5C","index":10,"n_rows":88,"n_cols":7,"rows_kept":88}
["Gene Set","N genes","Beta","Beta STD","SE","P","Pbon"]
["GO_bp:go_reverse_cholesterol_transport",17,3.1403,0.092481,0.25153,{"v":6.3553e-36,"d":"6.36E-36"},{"v":9.84308864e-32,"d":"9.84E-32"}]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_remodeling",13,3.4523,0.088914,0.29422,{"v":5.5959e-32,"d":"5.60E-32"},{"v":8.66637033e-28,"d":"8.67E-28"}]
["GO_bp:go_very_low_density_lipoprotein_particle_remodeling",11,3.5664,0.084497,0.31746,{"v":1.7395E-29,"d":"1.74E-29"},{"v":2.6937897e-25,"d":"2.69E-25"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_remodeling",32,1.9582,0.07909,0.17691,{"v":1.1004e-28,"d":"1.10E-28"},{"v":1.7039694E-24,"d":"1.70E-24"}]
["GO_mf:go_apolipoprotein_binding",17,2.679,0.078895,0.25089,{"v":7.7427e-27,"d":"7.74E-27"},{"v":1.198879668E-22,"d":"1.20E-22"}]
["GO_bp:go_protein_containing_complex_remodeling",30,1.9092,0.074664,0.18206,{"v":5.9366e-26,"d":"5.94E-26"},{"v":9.19163778e-22,"d":"9.19E-22"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly_remodeling_and_clearance",71,1.0719,0.064424,0.10787,{"v":1.6431E-23,"d":"1.64E-23"},{"v":2.54384742e-19,"d":"2.54E-19"}]
["GO_bp:go_high_density_lipoprotein_particle_remodeling",17,2.3364,0.068805,0.2363,{"v":2.7037e-23,"d":"2.70E-23"},{"v":4.18559797e-19,"d":"4.19E-19"}]
["GO_bp:go_sterol_transport",94,0.98216,0.067879,0.10135,{"v":1.8685E-22,"d":"1.87E-22"},{"v":2.892438E-18,"d":"2.89E-18"}]
["GO_bp:go_protein_lipid_complex_subunit_organization",50,1.3099,0.066103,0.13814,{"v":1.3894e-21,"d":"1.39E-21"},{"v":2.15065226E-17,"d":"2.15E-17"}]
["GO_mf:go_apolipoprotein_a_i_binding",5,4.4222,0.070649,0.46997,{"v":2.7843e-21,"d":"2.78E-21"},{"v":4.30953954e-17,"d":"4.31E-17"}]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_clearance",9,3.2138,0.068878,0.34534,{"v":7.3831e-21,"d":"7.38E-21"},{"v":1.142682387E-16,"d":"1.14E-16"}]
["GO_bp:go_lipid_homeostasis",128,0.73733,0.059413,0.080016,{"v":1.7297e-20,"d":"1.73E-20"},{"v":2.67688372E-16,"d":"2.68E-16"}]
["GO_cc:go_protein_lipid_complex",40,1.3267,0.059898,0.14421,{"v":1.9879e-20,"d":"1.99E-20"},{"v":3.07627525e-16,"d":"3.08E-16"}]
["GO_bp:go_sterol_homeostasis",78,0.95786,0.060328,0.10506,{"v":4.2489e-20,"d":"4.25E-20"},{"v":6.57474786e-16,"d":"6.57E-16"}]
["GO_cc:go_high_density_lipoprotein_particle",27,1.6243,0.060268,0.18293,{"v":3.6768e-19,"d":"3.68E-19"},{"v":5.68911264e-15,"d":"5.69E-15"}]
["GO_bp:go_lipoprotein_metabolic_process",30,1.6373,0.06403,0.18737,{"v":1.2863E-18,"d":"1.29E-18"},{"v":1.99016336e-14,"d":"1.99E-14"}]
["GO_bp:go_regulation_of_sterol_transport",45,1.2902,0.061775,0.14835,{"v":1.8479E-18,"d":"1.85E-18"},{"v":2.85888609e-14,"d":"2.86E-14"}]
["GO_bp:go_regulation_of_plasma_lipoprotein_particle_levels",86,0.8326,0.055052,0.098491,{"v":1.5202E-17,"d":"1.52E-17"},{"v":2.3517494e-13,"d":"2.35E-13"}]
["GO_bp:go_cholesterol_efflux",41,1.1913,0.054449,0.14461,{"v":9.3789e-17,"d":"9.38E-17"},{"v":1.450822041e-12,"d":"1.45E-12"}]
["Curated_gene_sets:reactome_chylomicron_clearance",5,3.5189,0.056218,0.42966,{"v":1.3943E-16,"d":"1.39E-16"},{"v":2.15670324e-12,"d":"2.16E-12"}]
["GO_bp:go_phospholipid_homeostasis",10,2.4853,0.056144,0.31245,{"v":9.5433e-16,"d":"9.54E-16"},{"v":1.476062211e-11,"d":"1.48E-11"}]
["GO_bp:go_phospholipid_efflux",12,2.5634,0.063432,0.32291,{"v":1.0836e-15,"d":"1.08E-15"},{"v":1.67589576e-11,"d":"1.68E-11"}]
["GO_bp:go_organic_hydroxy_compound_transport",239,0.49155,0.053968,0.063331,{"v":4.4173e-15,"d":"4.42E-15"},{"v":6.83135445e-11,"d":"6.83E-11"}]
["Curated_gene_sets:reactome_chylomicron_remodeling",10,2.7206,0.061459,0.35514,{"v":9.7321e-15,"d":"9.73E-15"},{"v":1.504971944e-10,"d":"1.50E-10"}]
["GO_bp:go_regulation_of_lipoprotein_lipase_activity",21,1.7047,0.055791,0.2249,{"v":1.8156e-14,"d":"1.82E-14"},{"v":2.80746228e-10,"d":"2.81E-10"}]
["GO_bp:go_protein_lipid_complex_assembly",32,1.2987,0.052451,0.17358,{"v":3.8372e-14,"d":"3.84E-14"},{"v":5.93307864e-10,"d":"5.93E-10"}]
["GO_mf:go_protein_lipid_complex_binding",28,1.5024,0.056766,0.20317,{"v":7.4006e-14,"d":"7.40E-14"},{"v":1.144206766E-9,"d":"1.14E-09"}]
["Curated_gene_sets:reactome_hdl_remodeling",10,2.1721,0.049068,0.29724,{"v":1.4184E-13,"d":"1.42E-13"},{"v":2.1928464E-9,"d":"2.19E-09"}]
["GO_bp:go_acylglycerol_homeostasis",33,1.0964,0.044968,0.1516,{"v":2.4709e-13,"d":"2.47E-13"},{"v":3.81976431e-09,"d":"3.82E-09"}]
["Curated_gene_sets:reactome_assembly_of_active_lpl_and_lipc_lipase_complexes",19,1.6903,0.052621,0.24064,{"v":1.1169E-12,"d":"1.12E-12"},{"v":1.72650402e-08,"d":"1.73E-08"}]
["GO_bp:go_steroid_metabolic_process",303,0.37229,0.045947,0.053513,{"v":1.7979E-12,"d":"1.80E-12"},{"v":2.77901403e-08,"d":"2.78E-08"}]
["GO_cc:go_triglyceride_rich_plasma_lipoprotein_particle",20,1.5449,0.049344,0.22321,{"v":2.3115E-12,"d":"2.31E-12"},{"v":3.5726544E-8,"d":"3.57E-08"}]
["GO_bp:go_regulation_of_phospholipid_catabolic_process",6,3.0073,0.052629,0.43591,{"v":2.7064e-12,"d":"2.71E-12"},{"v":4.1827412E-8,"d":"4.18E-08"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly",19,1.6273,0.050662,0.23864,{"v":4.7252e-12,"d":"4.73E-12"},{"v":7.30232408e-08,"d":"7.30E-08"}]
["GO_bp:go_chylomicron_remodeling",9,2.538,0.054394,0.38119,{"v":1.4271E-11,"d":"1.43E-11"},{"v":2.20529763e-07,"d":"2.21E-07"}]
["GO_bp:go_sterol_metabolic_process",96,0.61489,0.042944,0.09292,{"v":1.8804e-11,"d":"1.88E-11"},{"v":2.90559408E-7,"d":"2.91E-07"}]
["GO_bp:go_phosphatidylcholine_catabolic_process",8,2.1867,0.044187,0.33105,{"v":2.0359e-11,"d":"2.04E-11"},{"v":3.14566909E-7,"d":"3.15E-07"}]
["GO_bp:go_high_density_lipoprotein_particle_assembly",15,1.4913,0.041256,0.2263,{"v":2.262e-11,"d":"2.26E-11"},{"v":3.49479E-7,"d":"3.49E-07"}]
["GO_bp:go_high_density_lipoprotein_particle_clearance",13,1.6642,0.042862,0.25333,{"v":2.5997e-11,"d":"2.60E-11"},{"v":4.01627653e-07,"d":"4.02E-07"}]
["GO_bp:go_plasma_lipoprotein_particle_clearance",54,0.78939,0.041393,0.1214,{"v":4.0517E-11,"d":"4.05E-11"},{"v":6.25906616e-07,"d":"6.26E-07"}]
["GO_bp:go_secondary_alcohol_metabolic_process",85,0.62269,0.040933,0.095943,{"v":4.3996e-11,"d":"4.40E-11"},{"v":6.79606212e-07,"d":"6.80E-07"}]
["GO_cc:go_chylomicron",13,1.7426,0.044881,0.26945,{"v":5.1188e-11,"d":"5.12E-11"},{"v":7.90649848e-07,"d":"7.91E-07"}]
["GO_bp:go_lipid_localization",388,0.32186,0.044852,0.050031,{"v":6.4063e-11,"d":"6.41E-11"},{"v":9.89453035e-07,"d":"9.89E-07"}]
["Curated_gene_sets:reactome_vldl_assembly",5,2.8199,0.04505,0.45107,{"v":2.0791e-10,"d":"2.08E-10"},{"v":3.21096204e-06,"d":"3.21E-06"}]
["GO_bp:go_intestinal_absorption",35,1.0308,0.043537,0.16553,{"v":2.4269e-10,"d":"2.43E-10"},{"v":3.74786167e-06,"d":"3.75E-06"}]
["GO_bp:go_steroid_esterification",14,1.5461,0.041322,0.25066,{"v":3.5304E-10,"d":"3.53E-10"},{"v":5.45164368e-06,"d":"5.45E-06"}]
["GO_bp:go_negative_regulation_of_sterol_transport",12,1.7584,0.043513,0.28799,{"v":5.2225e-10,"d":"5.22E-10"},{"v":8.06406225e-06,"d":"8.06E-06"}]
["GO_bp:go_very_low_density_lipoprotein_particle_clearance",9,1.7812,0.038174,0.30519,{"v":2.7156E-9,"d":"2.72E-09"},{"v":4.1928864e-05,"d":"4.19E-05"}]
["GO_mf:go_sterol_transporter_activity",34,0.9252,0.038516,0.1597,{"v":3.5114e-09,"d":"3.51E-09"},{"v":5.42125046e-05,"d":"5.42E-05"}]
["GO_cc:go_intermediate_density_lipoprotein_particle",5,3.0144,0.048157,0.52928,{"v":6.2585e-09,"d":"6.26E-09"},{"v":9.6618723E-5,"d":"9.66E-05"}]
["GO_bp:go_chylomicron_assembly",10,2.0506,0.046324,0.36222,{"v":7.6318e-09,"d":"7.63E-09"},1.178120966E-4]
["GO_bp:go_regulation_of_lipid_localization",135,0.47738,0.039497,0.084363,{"v":7.7473e-09,"d":"7.75E-09"},0.0001195873228]
["GO_bp:go_cholesterol_storage",17,1.3782,0.040586,0.24493,{"v":9.317E-9,"d":"9.32E-09"},1.43807895E-4]
["Curated_gene_sets:schmidt_por_targets_in_limb_bud_dn",7,2.2721,0.042948,0.41076,{"v":1.6102e-08,"d":"1.61E-08"},0.000248518268]
["GO_bp:go_regulation_of_cholesterol_efflux",23,1.036,0.035482,0.18854,{"v":1.9806e-08,"d":"1.98E-08"},0.000305665998]
["GO_bp:go_negative_regulation_of_lipid_localization",42,0.81256,0.037588,0.14791,{"v":1.9958e-08,"d":"2.00E-08"},0.000307991856]
["GO_mf:go_phosphatidylcholine_sterol_o_acyltransferase_activator_activity",6,1.9875,0.034783,0.362,{"v":2.0312E-8,"d":"2.03E-08"},0.000313434472]
["Curated_gene_sets:reactome_abacavir_transmembrane_transport",5,2.6919,0.043006,0.49089,{"v":2.1112e-08,"d":"2.11E-08"},3.2575816E-4]
["GO_bp:go_phospholipid_catabolic_process",38,0.84626,0.03724,0.15433,{"v":2.1158E-8,"d":"2.12E-08"},3.26446782E-4]
["GO_bp:go_regulation_of_macrophage_derived_foam_cell_differentiation",30,1.0129,0.039612,0.1853,{"v":2.3312e-08,"d":"2.33E-08"},0.000359657536]
["GO_bp:go_receptor_mediated_endocytosis_involved_in_cholesterol_transport",5,2.3774,0.037982,0.43604,{"v":2.5188E-8,"d":"2.52E-08"},0.000388575276]
["GO_bp:go_phospholipid_transport",88,0.58991,0.039453,0.10868,{"v":2.8845e-08,"d":"2.88E-08"},4.4496297E-4]
["GO_bp:go_low_density_lipoprotein_particle_remodeling",14,1.4143,0.0378,0.26258,{"v":3.6448e-08,"d":"3.64E-08"},0.0005622104]
["GO_mf:go_cholesterol_transporter_activity",20,1.0999,0.035131,0.20693,{"v":5.3873e-08,"d":"5.39E-08"},0.000830937152]
["GO_bp:go_intestinal_lipid_absorption",16,1.2449,0.035569,0.23597,{"v":6.6809E-8,"d":"6.68E-08"},1.030395207E-3]
["GO_mf:go_low_density_lipoprotein_particle_binding",16,1.4199,0.040566,0.27186,{"v":8.9186e-08,"d":"8.92E-08"},0.001375426492]
["GO_bp:go_regulation_of_lipid_transport",105,0.49133,0.035879,0.094882,{"v":1.1315E-7,"d":"1.13E-07"},1.74488615E-3]
["GO_bp:go_anion_homeostasis",56,0.63312,0.033806,0.12428,{"v":1.7685E-7,"d":"1.77E-07"},0.002727027]
["Curated_gene_sets:reactome_plasma_lipoprotein_clearance",33,0.73666,0.030213,0.14495,{"v":1.8842e-07,"d":"1.88E-07"},0.00290524798]
["GO_bp:go_glycerolipid_catabolic_process",61,0.66853,0.037252,0.13163,{"v":1.9174E-7,"d":"1.92E-07"},2.95624732E-3]
["GO_bp:go_positive_regulation_of_sterol_transport",22,0.97028,0.032501,0.19297,{"v":2.4998e-07,"d":"2.50E-07"},3.85394166E-3]
["GO_bp:go_lipid_storage",67,0.60866,0.035539,0.12143,{"v":2.7115e-07,"d":"2.71E-07"},0.0041800484]
["Curated_gene_sets:roversi_glioma_copy_number_up",97,0.60722,0.042628,0.12128,{"v":2.7921e-07,"d":"2.79E-07"},0.00430402215]
["GO_bp:go_positive_regulation_of_cholesterol_storage",7,2.0818,0.03935,0.41671,{"v":2.9583e-07,"d":"2.96E-07"},0.00455992362]
["GO_bp:go_organophosphate_ester_transport",115,0.45521,0.034779,0.092072,{"v":3.8611e-07,"d":"3.86E-07"},0.00595111343]
["GO_mf:go_lipid_transporter_activity",144,0.39169,0.033463,0.079921,{"v":4.8089e-07,"d":"4.81E-07"},0.00741147668]
["GO_bp:go_positive_regulation_of_cholesterol_esterification",9,1.5405,0.033016,0.31521,{"v":5.1582e-07,"d":"5.16E-07"},7.94930202E-3]
["GO_bp:go_regulation_of_lipoprotein_metabolic_process",10,1.5255,0.034462,0.3156,{"v":6.7564e-07,"d":"6.76E-07"},0.0104116124]
["GO_bp:go_regulation_of_cdc42_protein_signal_transduction",7,2.0092,0.037979,0.41938,{"v":8.3626E-7,"d":"8.36E-07"},0.01288593034]
["GO_bp:go_neutral_lipid_metabolic_process",119,0.42524,0.033047,0.089906,{"v":1.1321e-06,"d":"1.13E-06"},0.0174433968]
["GO_bp:go_lipid_digestion",18,1.0534,0.031921,0.22316,{"v":1.1854e-06,"d":"1.19E-06"},0.0182634578]
["GO_bp:go_organic_hydroxy_compound_metabolic_process",473,0.20369,0.03127,0.043214,{"v":1.2261E-6,"d":"1.23E-06"},0.0188892966]
["GO_bp:go_foam_cell_differentiation",36,0.74567,0.03194,0.16285,{"v":2.3527e-06,"d":"2.35E-06"},0.0362433435]
["GO_bp:go_positive_regulation_of_receptor_catabolic_process",5,2.1832,0.034879,0.47756,{"v":2.4362e-06,"d":"2.44E-06"},0.0375272248]
["GO_bp:go_negative_regulation_of_lipoprotein_lipase_activity",6,1.8055,0.031596,0.39571,{"v":2.5427e-06,"d":"2.54E-06"},0.0391652081]
["Curated_gene_sets:reactome_chylomicron_assembly",10,1.4319,0.032347,0.31638,{"v":3.0284e-06,"d":"3.03E-06"},0.0466434168]

{"sheet":"ST5D","index":11,"n_rows":87,"n_cols":7,"rows_kept":87}
["Gene Set","N genes","Beta","Beta STD","SE","P","Pbon"]
["GO_bp:go_reverse_cholesterol_transport",17,3.0571,0.090028,0.25419,{"v":1.7287e-33,"d":"1.73E-33"},{"v":2.67741056E-29,"d":"2.68E-29"}]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_remodeling",13,3.1753,0.08178,0.29743,{"v":7.9539e-27,"d":"7.95E-27"},{"v":1.231820493e-22,"d":"1.23E-22"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_remodeling",32,1.8293,0.073881,0.17882,{"v":8.5284e-25,"d":"8.53E-25"},{"v":1.320708024E-20,"d":"1.32E-20"}]
["GO_bp:go_very_low_density_lipoprotein_particle_remodeling",11,3.2797,0.077704,0.32091,{"v":9.4377e-25,"d":"9.44E-25"},{"v":1.461427845e-20,"d":"1.46E-20"}]
["GO_mf:go_apolipoprotein_binding",17,2.4882,0.073277,0.25358,{"v":5.6917e-23,"d":"5.69E-23"},{"v":8.81302828e-19,"d":"8.81E-19"}]
["GO_bp:go_protein_containing_complex_remodeling",30,1.8022,0.07048,0.184,{"v":6.7892e-23,"d":"6.79E-23"},{"v":1.051171836E-18,"d":"1.05E-18"}]
["GO_mf:go_apolipoprotein_a_i_binding",5,4.4441,0.070999,0.4748,{"v":4.4525e-21,"d":"4.45E-21"},{"v":6.8933605e-17,"d":"6.89E-17"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly_remodeling_and_clearance",71,1.0123,0.060837,0.10901,{"v":8.9319e-21,"d":"8.93E-21"},{"v":1.382747439e-16,"d":"1.38E-16"}]
["GO_bp:go_sterol_transport",94,0.94994,0.065653,0.10241,{"v":9.7924e-21,"d":"9.79E-21"},{"v":1.51586352E-16,"d":"1.52E-16"}]
["GO_bp:go_high_density_lipoprotein_particle_remodeling",17,2.1955,0.064655,0.23881,{"v":2.1087e-20,"d":"2.11E-20"},{"v":3.26405673e-16,"d":"3.26E-16"}]
["GO_bp:go_protein_lipid_complex_subunit_organization",50,1.2617,0.063671,0.13959,{"v":8.6906e-20,"d":"8.69E-20"},{"v":1.345131068E-15,"d":"1.35E-15"}]
["GO_bp:go_sterol_homeostasis",78,0.94539,0.059543,0.10615,{"v":2.8846e-19,"d":"2.88E-19"},{"v":4.46449542e-15,"d":"4.46E-15"}]
["GO_bp:go_lipid_homeostasis",128,0.71895,0.057932,0.08085,{"v":3.2692e-19,"d":"3.27E-19"},{"v":5.05941392E-15,"d":"5.06E-15"}]
["GO_cc:go_protein_lipid_complex",40,1.292,0.058329,0.14572,{"v":4.1318e-19,"d":"4.13E-19"},{"v":6.3939605e-15,"d":"6.39E-15"}]
["GO_cc:go_high_density_lipoprotein_particle",27,1.5887,0.058949,0.18483,{"v":4.4837e-18,"d":"4.48E-18"},{"v":6.93807738e-14,"d":"6.94E-14"}]
["GO_bp:go_lipoprotein_metabolic_process",30,1.6137,0.063107,0.18931,{"v":8.3111e-18,"d":"8.31E-18"},{"v":1.285976503E-13,"d":"1.29E-13"}]
["GO_bp:go_regulation_of_plasma_lipoprotein_particle_levels",86,0.83675,0.055326,0.099504,{"v":2.2184e-17,"d":"2.22E-17"},{"v":3.43230848e-13,"d":"3.43E-13"}]
["GO_bp:go_regulation_of_sterol_transport",45,1.2397,0.059354,0.1499,{"v":7.1837e-17,"d":"7.18E-17"},{"v":1.111390227E-12,"d":"1.11E-12"}]
["GO_bp:go_phospholipid_homeostasis",10,2.6006,0.058749,0.31561,{"v":9.2127e-17,"d":"9.21E-17"},{"v":1.42520469E-12,"d":"1.43E-12"}]
["GO_bp:go_cholesterol_efflux",41,1.1329,0.051779,0.14613,{"v":4.7451e-15,"d":"4.75E-15"},{"v":7.34019519e-11,"d":"7.34E-11"}]
["Curated_gene_sets:reactome_chylomicron_clearance",5,3.3474,0.053478,0.43416,{"v":6.6162e-15,"d":"6.62E-15"},{"v":1.023393816E-10,"d":"1.02E-10"}]
["GO_bp:go_triglyceride_rich_lipoprotein_particle_clearance",9,2.687,0.057588,0.34915,{"v":7.3932e-15,"d":"7.39E-15"},{"v":1.143506244E-10,"d":"1.14E-10"}]
["GO_bp:go_organic_hydroxy_compound_transport",239,0.48159,0.052875,0.063987,{"v":2.7315e-14,"d":"2.73E-14"},{"v":4.2245379E-10,"d":"4.22E-10"}]
["GO_bp:go_phospholipid_efflux",12,2.3892,0.059122,0.3263,{"v":1.2739E-13,"d":"1.27E-13"},{"v":1.97008635e-09,"d":"1.97E-09"}]
["GO_bp:go_acylglycerol_homeostasis",33,1.1117,0.045596,0.15315,{"v":2.0314e-13,"d":"2.03E-13"},{"v":3.14135696e-09,"d":"3.14E-09"}]
["GO_bp:go_steroid_metabolic_process",303,0.3917,0.048343,0.054056,{"v":2.229e-13,"d":"2.23E-13"},{"v":3.4467027e-09,"d":"3.45E-09"}]
["GO_mf:go_protein_lipid_complex_binding",28,1.4692,0.055513,0.20527,{"v":4.2698e-13,"d":"4.27E-13"},{"v":6.60196476e-09,"d":"6.60E-09"}]
["GO_bp:go_protein_lipid_complex_assembly",32,1.2249,0.049472,0.17539,{"v":1.4883E-12,"d":"1.49E-12"},{"v":2.30106063e-08,"d":"2.30E-08"}]
["Curated_gene_sets:reactome_assembly_of_active_lpl_and_lipc_lipase_complexes",19,1.6813,0.052342,0.24312,{"v":2.4096e-12,"d":"2.41E-12"},{"v":3.7252416e-08,"d":"3.73E-08"}]
["GO_bp:go_secondary_alcohol_metabolic_process",85,0.66618,0.043792,0.096913,{"v":3.225e-12,"d":"3.23E-12"},{"v":4.9855275e-08,"d":"4.99E-08"}]
["GO_bp:go_sterol_metabolic_process",96,0.63529,0.044369,0.093868,{"v":6.7346E-12,"d":"6.73E-12"},{"v":1.041034468e-07,"d":"1.04E-07"}]
["GO_bp:go_high_density_lipoprotein_particle_assembly",15,1.5368,0.042515,0.22861,{"v":9.2114e-12,"d":"9.21E-12"},{"v":1.423806098e-07,"d":"1.42E-07"}]
["GO_bp:go_regulation_of_phospholipid_catabolic_process",6,2.9169,0.051046,0.44042,{"v":1.8119e-11,"d":"1.81E-11"},{"v":2.80047264E-7,"d":"2.80E-07"}]
["GO_bp:go_regulation_of_lipoprotein_lipase_activity",21,1.494,0.048896,0.2273,{"v":2.5366E-11,"d":"2.54E-11"},{"v":3.9203153e-07,"d":"3.92E-07"}]
["GO_bp:go_lipid_localization",388,0.32832,0.045751,0.050543,{"v":4.2417e-11,"d":"4.24E-11"},{"v":6.55512318e-07,"d":"6.56E-07"}]
["Curated_gene_sets:reactome_plasma_lipoprotein_assembly",19,1.5649,0.048717,0.24112,{"v":4.4018e-11,"d":"4.40E-11"},{"v":6.80210154e-07,"d":"6.80E-07"}]
["GO_bp:go_steroid_esterification",14,1.635,0.043698,0.25321,{"v":5.4726e-11,"d":"5.47E-11"},{"v":8.45626152E-7,"d":"8.46E-07"}]
["Curated_gene_sets:reactome_chylomicron_remodeling",10,2.3099,0.052182,0.35896,{"v":6.3313e-11,"d":"6.33E-11"},{"v":9.78249163e-07,"d":"9.78E-07"}]
["Curated_gene_sets:reactome_hdl_remodeling",10,1.9229,0.043439,0.30039,{"v":7.8965e-11,"d":"7.90E-11"},{"v":1.22000925e-06,"d":"1.22E-06"}]
["GO_bp:go_plasma_lipoprotein_particle_clearance",54,0.77653,0.040719,0.12265,{"v":1.244E-10,"d":"1.24E-10"},{"v":1.9218556e-06,"d":"1.92E-06"}]
["GO_bp:go_intestinal_absorption",35,1.0538,0.044508,0.16722,{"v":1.5075E-10,"d":"1.51E-10"},{"v":2.328786e-06,"d":"2.33E-06"}]
["GO_bp:go_phosphatidylcholine_catabolic_process",8,2.1013,0.042461,0.33448,{"v":1.7052E-10,"d":"1.71E-10"},{"v":2.63402244e-06,"d":"2.63E-06"}]
["Curated_gene_sets:reactome_vldl_assembly",5,2.736,0.04371,0.45574,{"v":9.85e-10,"d":"9.85E-10"},{"v":1.521431E-5,"d":"1.52E-05"}]
["GO_mf:go_phosphatidylcholine_sterol_o_acyltransferase_activator_activity",6,2.1665,0.037915,0.36566,{"v":1.5903E-9,"d":"1.59E-09"},{"v":2.45621835e-05,"d":"2.46E-05"}]
["GO_cc:go_triglyceride_rich_plasma_lipoprotein_particle",20,1.3189,0.042124,0.22558,{"v":2.5539E-9,"d":"2.55E-09"},{"v":3.94424316e-05,"d":"3.94E-05"}]
["GO_bp:go_regulation_of_cholesterol_efflux",23,1.1007,0.037697,0.19045,{"v":3.8124e-09,"d":"3.81E-09"},{"v":5.88748932e-05,"d":"5.89E-05"}]
["GO_bp:go_regulation_of_lipoprotein_metabolic_process",10,1.8275,0.041285,0.31875,{"v":5.001e-09,"d":"5.00E-09"},{"v":7.7225442e-05,"d":"7.72E-05"}]
["GO_mf:go_cholesterol_transporter_activity",20,1.1836,0.037803,0.20903,{"v":7.5855e-09,"d":"7.59E-09"},0.0001171277055]
["GO_mf:go_sterol_transporter_activity",34,0.91352,0.038029,0.16135,{"v":7.6089e-09,"d":"7.61E-09"},1.17481416E-4]
["GO_bp:go_anion_homeostasis",56,0.70775,0.037791,0.12554,{"v":8.7396e-09,"d":"8.74E-09"},0.0001349306844]
["GO_bp:go_high_density_lipoprotein_particle_clearance",13,1.4363,0.036993,0.25602,{"v":1.0249E-8,"d":"1.02E-08"},0.000158224062]
["GO_bp:go_alcohol_metabolic_process",220,0.34593,0.036457,0.061662,{"v":1.0262E-8,"d":"1.03E-08"},0.000158414494]
["GO_bp:go_intestinal_lipid_absorption",16,1.3332,0.038089,0.23836,{"v":1.1322E-8,"d":"1.13E-08"},0.000174766392]
["GO_bp:go_organic_hydroxy_compound_metabolic_process",473,0.24378,0.037424,0.043646,{"v":1.1834E-8,"d":"1.18E-08"},0.00018265779]
["GO_bp:go_cholesterol_storage",17,1.3817,0.04069,0.24744,{"v":1.1929E-8,"d":"1.19E-08"},0.000184112186]
["GO_bp:go_phospholipid_catabolic_process",38,0.86448,0.038042,0.15591,{"v":1.494E-8,"d":"1.49E-08"},2.3056902E-4]
["GO_mf:go_low_density_lipoprotein_particle_binding",16,1.49,0.042569,0.27464,{"v":2.9321e-08,"d":"2.93E-08"},0.000452481672]
["GO_bp:go_lipid_storage",67,0.66338,0.038734,0.12266,{"v":3.2215e-08,"d":"3.22E-08"},0.000497109665]
["GO_bp:go_regulation_of_lipid_localization",135,0.45888,0.037966,0.085235,{"v":3.6961e-08,"d":"3.70E-08"},5.7030823E-4]
["Curated_gene_sets:schmidt_por_targets_in_limb_bud_dn",7,2.232,0.042189,0.415,{"v":3.806e-08,"d":"3.81E-08"},0.00058722774]
["GO_bp:go_low_density_lipoprotein_particle_remodeling",14,1.4235,0.038045,0.26528,{"v":4.0757e-08,"d":"4.08E-08"},6.28798996E-4]
["GO_bp:go_positive_regulation_of_sterol_transport",22,1.0299,0.034498,0.19493,{"v":6.421e-08,"d":"6.42E-08"},0.00099056767]
["GO_bp:go_chylomicron_remodeling",9,2.0282,0.043469,0.38528,{"v":7.1167e-08,"d":"7.12E-08"},0.001097822142]
["GO_cc:go_chylomicron",13,1.4322,0.036886,0.27232,{"v":7.3218e-08,"d":"7.32E-08"},0.00112938765]
["GO_bp:go_chylomicron_assembly",10,1.9087,0.04312,0.36598,{"v":9.275e-08,"d":"9.28E-08"},1.430576E-3]
["GO_bp:go_positive_regulation_of_cholesterol_esterification",9,1.6339,0.035017,0.31843,{"v":1.4555E-7,"d":"1.46E-07"},0.00224481765]
["Curated_gene_sets:roversi_glioma_copy_number_up",97,0.62017,0.043537,0.12252,{"v":2.0972E-7,"d":"2.10E-07"},0.00323430184]
["GO_bp:go_lipid_digestion",18,1.1276,0.034169,0.22543,{"v":2.8632e-07,"d":"2.86E-07"},4.41534072E-3]
["GO_bp:go_lipid_metabolic_process",1208,0.1404,0.033777,0.028215,{"v":3.2734e-07,"d":"3.27E-07"},0.0050475828]
["GO_bp:go_receptor_mediated_endocytosis_involved_in_cholesterol_transport",5,2.1869,0.034938,0.44057,{"v":3.4883e-07,"d":"3.49E-07"},0.00537860977]
["GO_bp:go_negative_regulation_of_lipid_localization",42,0.73261,0.03389,0.14945,{"v":4.7855e-07,"d":"4.79E-07"},0.0073782839]
["GO_bp:go_regulation_of_cholesterol_esterification",11,1.4553,0.03448,0.30073,{"v":6.5735e-07,"d":"6.57E-07"},0.01013436495]
["GO_bp:go_regulation_of_lipid_transport",105,0.46297,0.033808,0.095865,{"v":6.9027E-7,"d":"6.90E-07"},0.01064120232]
["GO_mf:go_lipid_transporter_activity",144,0.38303,0.032723,0.080744,{"v":1.0573E-6,"d":"1.06E-06"},0.0162982795]
["GO_bp:go_regulation_of_steroid_metabolic_process",114,0.41215,0.031353,0.086963,{"v":1.0801E-6,"d":"1.08E-06"},0.0166486614]
["Curated_gene_sets:reactome_plasma_lipoprotein_clearance",33,0.69313,0.028428,0.14645,{"v":1.1152e-06,"d":"1.12E-06"},0.0171885776]
["GO_bp:go_neutral_lipid_metabolic_process",119,0.4298,0.033401,0.090829,{"v":1.1201e-06,"d":"1.12E-06"},0.0172629812]
["GO_bp:go_regulation_of_intestinal_absorption",8,1.4297,0.02889,0.30364,{"v":1.2568E-6,"d":"1.26E-06"},0.0193685448]
["Curated_gene_sets:reactome_abacavir_transmembrane_transport",5,2.315,0.036984,0.49605,{"v":1.5405e-06,"d":"1.54E-06"},0.023739105]
["GO_bp:go_glycerolipid_catabolic_process",61,0.61993,0.034544,0.133,{"v":1.5823e-06,"d":"1.58E-06"},0.0243816607]
["GO_bp:go_regulation_of_macrophage_derived_foam_cell_differentiation",30,0.8714,0.034079,0.18725,{"v":1.6417e-06,"d":"1.64E-06"},0.0252953136]
["GO_bp:go_phospholipid_transport",88,0.50935,0.034066,0.10981,{"v":1.7695E-6,"d":"1.77E-06"},0.0272626865]
["GO_bp:go_acylglycerol_transport",4,2.6844,0.03836,0.58095,{"v":1.9252e-06,"d":"1.93E-06"},0.0296596312]
["GO_bp:go_positive_regulation_of_receptor_catabolic_process",5,2.2018,0.035176,0.48246,{"v":2.5303e-06,"d":"2.53E-06"},0.0389792715]
["GO_bp:go_regulation_of_lipid_metabolic_process",374,0.22278,0.030491,0.048829,{"v":2.5444e-06,"d":"2.54E-06"},0.0391939376]
["Curated_gene_sets:reactome_scavenging_by_class_b_receptors",6,1.8443,0.032277,0.40831,{"v":3.1562E-6,"d":"3.16E-06"},0.0486149486]

{"sheet":"ST6A","index":12,"n_rows":2894,"n_cols":37,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["GenomicLocus","IndSigSNP","chr","bp","snp","DateAddedToCatalog","PMID","FirstAuth","Date","Journal","Link","Study","Trait","InitialN","ReplicationN","Region","ReportedGene","MappedGene","UpGene","DownGene","SNP_Gene_ID","UpGeneDist","DownGeneDist","Strongest","SNPs","marged","SNP_ID_cur","Context","intergenic","RiskAF","P","Pmlog","Ptext","OrBeta","95CI","Platform","CNV"]
[3,"rs629301",1,109817192,"rs7528419","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7782,{"v":0,"d":"0.00E+00"},308.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[31,"rs3816117",16,56996211,"rs711752","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs711752-A","rs711752",0,711752,"splice_region_variant",0,"NR",{"v":4e-308,"d":"4.00E-308"},307.397940008672,{"$nulls":3},"NR [2501543] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1e-302,"d":"1.00E-302"},302,"(BIRC2)",1.6999545,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[3,"rs11102967",1,109815252,"rs611917","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs611917-A","rs611917",0,611917,"non_coding_transcript_exon_variant",0,0.6818,{"v":1E-300,"d":"1.00E-300"},300,null,0.1122,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7715,{"v":1E-300,"d":"1.00E-300"},300,null,0.1364,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.379,{"v":1E-300,"d":"1.00E-300"},300,null,0.1118,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19830170,"rs1569209","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,5400,106455,"rs1569209-T","rs1569209",0,1569209,"regulatory_region_variant",1,0.9206,{"v":1E-300,"d":"1.00E-300"},300,null,0.2112,"[0.2-0.22] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.685,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.216,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.213,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.208,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.219,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.683,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.218,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.212,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.6902,{"v":1E-300,"d":"1.00E-300"},300,null,0.2211,"[0.22-0.23] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.716,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.218,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.685,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.212,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.822,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.217,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.207,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.564,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.821,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11187324,"rs143020224","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs143020224-C","rs143020224",0,143020224,"intron_variant",0,0.8693,{"v":1E-300,"d":"1.00E-300"},300,null,0.1619,"[0.15-0.17] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs41290120",19,45319631,"rs118147862","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","BCAM","BCAM",null,null,"ENSG00000187244",null,null,"rs118147862-A","rs118147862",0,118147862,"intron_variant",0,0.0369,{"v":1E-300,"d":"1.00E-300"},300,null,0.3977,"[0.38-0.41] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.493,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.498,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.342,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.348,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","HERPUD1, CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-?","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":2e-300,"d":"2.00E-300"},299.698970004336,null,0.2656,"[0.25-0.28] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-297,"d":"3.00E-297"},296.52287874528,null,0.14,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19850099,"rs79407615","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,25329,86526,"rs79407615-T","rs79407615",0,79407615,"intergenic_variant",1,0.9025,{"v":3e-293,"d":"3.00E-293"},292.52287874528,null,0.1799,"[0.17-0.19] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":4E-289,"d":"4.00E-289"},288.397940008672,"(Trans-ethnic initial)",0.16,"[0.15-0.17] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[21,"rs201220977",10,65066186,"rs10761741","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean platelet volume","164,454 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.4182,{"v":5e-287,"d":"5.00E-287"},286.301029995663,null,0.1326053,"[0.13-0.14] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19q13.32","APOC1, APOE, APOC2","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.066,{"v":2e-286,"d":"2.00E-286"},285.698970004336,"(Trans-ethnic initial)",0.59,"[0.57-0.61] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[36,"rs151113958",19,11196886,"rs8106503","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,6784,3152,"rs8106503-T","rs8106503",0,8106503,"intergenic_variant",1,0.8354,{"v":2E-281,"d":"2.00E-281"},280.698970004336,null,0.1334,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-272,"d":"2.00E-272"},271.698970004336,"(EA)",0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-268,"d":"5.00E-268"},267.301029995663,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,"NR",{"v":1e-266,"d":"1.00E-266"},266,null,0.122,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":4E-262,"d":"4.00E-262"},261.397940008672,null,0.221,"[NR] unit decrease","NR [NR] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3642,{"v":3e-259,"d":"3.00E-259"},258.52287874528,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0149,{"v":3e-257,"d":"3.00E-257"},256.52287874528,null,0.3952,"[0.37-0.42] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.413,{"v":4e-253,"d":"4.00E-253"},252.397940008672,"(Trans-ethnic initial)",0.115,"[0.11-0.12] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[36,"rs151113958",19,11191197,"rs114846969","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19p13.2","NR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,1095,8841,"rs114846969-A","rs114846969",0,114846969,"intergenic_variant",1,0.1172,{"v":2e-252,"d":"2.00E-252"},251.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-251,"d":"3.00E-251"},250.52287874528,"(EA)",0.141,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.393,{"v":4e-251,"d":"4.00E-251"},250.397940008672,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":3e-250,"d":"3.00E-250"},249.52287874528,"(EA)",0.169,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3E-249,"d":"3.00E-249"},248.52287874528,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",0.76,"[0.72-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2E-247,"d":"2.00E-247"},246.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":2e-245,"d":"2.00E-245"},244.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-242,"d":"5.00E-242"},241.301029995663,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":7e-242,"d":"7.00E-242"},241.154901959985,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":5e-241,"d":"5.00E-241"},240.301029995663,null,0.167,"[NR] unit decrease","NR [NR] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-239,"d":"1.00E-239"},239,"(Centrosomal protein of 57 kDa, CEP57.11276.1.3)",1.33,"[1.25-1.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":2e-239,"d":"2.00E-239"},238.698970004336,null,0.115,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93,{"v":8e-239,"d":"8.00E-239"},238.096910013008,null,0.413,"[0.39-0.44] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":1E-236,"d":"1.00E-236"},236,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1E-230,"d":"1.00E-230"},230,null,0.227,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.215441066,{"v":9e-230,"d":"9.00E-230"},229.04575749056,"(GRN)",0.727792,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[5,"rs562338",2,21299867,"rs577584","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,32922,46922,"rs577584-A","rs577584",0,577584,"intergenic_variant",1,0.6896,{"v":1e-229,"d":"1.00E-229"},229,null,0.1008,"[0.095-0.107] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-228,"d":"9.00E-228"},227.04575749056,null,0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-227,"d":"4.00E-227"},226.397940008672,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19819328,"rs325","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs325-T","rs325",0,325,"intron_variant",0,0.9032,{"v":4e-227,"d":"4.00E-227"},226.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":3E-226,"d":"3.00E-226"},225.52287874528,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","2q21.3","LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.711,{"v":2e-222,"d":"2.00E-222"},221.698970004336,"(Lactase-phlorizin hydrolase, LCT.9017.58.3)",0.78,"[0.74-0.82] unit increase","Affymetrix [10572788] (imputed)","N"]
[7,"rs11681659",2,136381348,"rs12465802","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","2q21.3","NR","R3HDM1",null,null,"ENSG00000048991",null,null,"rs12465802-A","rs12465802",0,12465802,"intron_variant",0,0.282,{"v":3e-218,"d":"3.00E-218"},217.52287874528,"(Lactase-phlorizin hydrolase, LCT.9017.58.3)",0.78,"[0.74-0.82] unit decrease","Affymetrix [10572788] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.879,{"v":5e-217,"d":"5.00E-217"},216.301029995663,"(Trans-ethnic initial)",0.17,"[0.16-0.18] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.367,{"v":1e-213,"d":"1.00E-213"},213,"(Trans-ethnic initial)",0.107,"[0.1-0.11] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":8e-211,"d":"8.00E-211"},210.096910013008,"(Granulins, GRN.4992.49.1)",0.83,"[0.77-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-210,"d":"4.00E-210"},209.397940008672,"(UBA2)",1.4728388,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","2q21.3","LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-G","rs4988235",0,4988235,"intron_variant",0,0.148,{"v":5e-210,"d":"5.00E-210"},209.301029995663,"(LCT)",0.963,"[0.91-1.02] unit decrease","Illumina [> 1000000] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":1E-206,"d":"1.00E-206"},206,"(EA)",0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":5E-205,"d":"5.00E-205"},204.301029995663,"(Protein CEI, C5orf38.6378.2.3)",1.25,"[1.17-1.33] unit decrease","Affymetrix [10572788] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(Trans-ethnic initial)",0.128,"[0.12-0.14] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(EA)",0.22,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.228,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":4e-202,"d":"4.00E-202"},201.397940008672,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":5e-202,"d":"5.00E-202"},201.301029995663,null,0.185,"[NR] unit decrease","NR [NR] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":1e-201,"d":"1.00E-201"},201,"(EA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":3E-201,"d":"3.00E-201"},200.52287874528,"(EA)",0.18,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":2E-200,"d":"2.00E-200"},199.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.13,{"v":2E-199,"d":"2.00E-199"},198.698970004336,null,0.17,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,"NR",{"v":3e-199,"d":"3.00E-199"},198.52287874528,null,0.186,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":1E-194,"d":"1.00E-194"},194,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,"NR",{"v":2E-191,"d":"2.00E-191"},190.698970004336,null,0.181,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,73025975,"rs13234131","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13234131-A","rs13234131",0,13234131,"intron_variant",0,0.8853,{"v":4e-191,"d":"4.00E-191"},190.397940008672,null,0.1275,"[0.12-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":1e-189,"d":"1.00E-189"},189,"(EA)",0.176,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":1e-188,"d":"1.00E-188"},188,null,0.107,"[NR] unit increase","NR [NR] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":8e-182,"d":"8.00E-182"},181.096910013008,null,0.168,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44773783,"rs199441","2019-02-01",30573740,"Yap CX","2018-12-20","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30573740","Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.","Male-pattern baldness","205,327 European ancestry males","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199441-A","rs199441",0,199441,"intron_variant",0,0.215491,{"v":1E-181,"d":"1.00E-181"},181,null,0.109361,"[0.1-0.12] unit decrease","NR [19129689] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":5e-181,"d":"5.00E-181"},180.301029995663,null,0.19,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":4e-179,"d":"4.00E-179"},178.397940008672,null,0.171,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.879,{"v":4E-176,"d":"4.00E-176"},175.397940008672,"(Trans-ethnic initial)",0.155,"[0.14-0.17] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":7E-176,"d":"7.00E-176"},175.154901959985,null,0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.015,{"v":8E-175,"d":"8.00E-175"},174.096910013008,null,0.325,"[0.3-0.35] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":1E-173,"d":"1.00E-173"},173,null,0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":1e-170,"d":"1.00E-170"},170,null,5.65,"[5.24-6.06] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":2E-170,"d":"2.00E-170"},169.698970004336,null,0.134,"[NR] unit decrease","NR [NR] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-170,"d":"4.00E-170"},169.397940008672,{"$nulls":3},"NR [2501749] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-169,"d":"1.00E-169"},169,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2e-168,"d":"2.00E-168"},167.698970004336,null,0.148,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":4E-167,"d":"4.00E-167"},166.397940008672,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":4E-165,"d":"4.00E-165"},164.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":3e-164,"d":"3.00E-164"},163.52287874528,null,0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-164,"d":"4.00E-164"},163.397940008672,null,0.144,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.897,{"v":9e-164,"d":"9.00E-164"},163.04575749056,"(EA)",0.184,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-162,"d":"1.00E-162"},162,"(CUB and zona pellucida-like domain-containing protein 1, CUZD1.7943.16.3)",1.14,"[1.06-1.22] unit decrease","Affymetrix [10572788] (imputed)","N"]
[17,"rs117026536",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.897,{"v":4e-162,"d":"4.00E-162"},161.397940008672,"(EA)",0.184,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":2e-161,"d":"2.00E-161"},160.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3798,{"v":3E-160,"d":"3.00E-160"},159.52287874528,null,0.0748,"[0.069-0.08] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":9e-160,"d":"9.00E-160"},159.04575749056,"(EA)",0.191,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2e-158,"d":"2.00E-158"},157.698970004336,"(EA)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0194,{"v":6E-158,"d":"6.00E-158"},157.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.896,{"v":9E-158,"d":"9.00E-158"},157.04575749056,"(EA)",0.182,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21291312,"rs548145","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24367,55477,"rs548145-T","rs548145",0,548145,"intergenic_variant",1,0.2416,{"v":6e-156,"d":"6.00E-156"},155.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.6,{"v":9e-155,"d":"9.00E-155"},154.04575749056,"(Triglycerides in very large HDL)",0.26,"[0.24-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[17,"rs117026536",8,19824563,"rs1059611","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs1059611-?","rs1059611",0,1059611,"3_prime_UTR_variant",0,"NR",{"v":1e-154,"d":"1.00E-154"},154,null,0.1698,"[0.16-0.18] unit decrease novel","Illumina [6108953] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-154,"d":"4.00E-154"},153.397940008672,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-154,"d":"9.00E-154"},153.04575749056,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.879,{"v":1e-152,"d":"1.00E-152"},152,"(EA)",0.168,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-151,"d":"4.00E-151"},150.397940008672,{"$nulls":3},"NR [25015711] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.13,{"v":1e-149,"d":"1.00E-149"},149,null,0.155,"[NR] unit increase","NR [NR] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.346,{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix [NR]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3E-148,"d":"3.00E-148"},147.52287874528,"(glucose/mannose)",0.041,"[0.037-0.045] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[18,"rs33924196",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7181,{"v":7e-148,"d":"7.00E-148"},147.154901959985,null,0.0776,"[0.072-0.083] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.892,{"v":2e-147,"d":"2.00E-147"},146.698970004336,"(EA)",0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-147,"d":"2.00E-147"},146.698970004336,"(VPS29)",1.2477906,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":1E-146,"d":"1.00E-146"},146,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2e-145,"d":"2.00E-145"},144.698970004336,null,0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":2e-142,"d":"2.00E-142"},141.698970004336,null,0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":7e-142,"d":"7.00E-142"},141.154901959985,null,0.25,"[0.23-0.27] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[29,"rs1077835",15,58723939,"rs2070895","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":1e-140,"d":"1.00E-140"},140,null,0.1322,"[0.12-0.14] unit increase novel","Illumina [6108953] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-140,"d":"4.00E-140"},139.397940008672,null,0.139,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,73001021,"rs35173225","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,7900,6503,"rs35173225-T","rs35173225",0,35173225,"intergenic_variant",1,0.108,{"v":1e-137,"d":"1.00E-137"},137,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-137,"d":"4.00E-137"},136.397940008672,"(Proteasome activator complex subunit 1, PSME1.5918.5.3)",1.06,"[0.98-1.14] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":8e-137,"d":"8.00E-137"},136.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":7e-135,"d":"7.00E-135"},134.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":9e-135,"d":"9.00E-135"},134.04575749056,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":2e-134,"d":"2.00E-134"},133.698970004336,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.981,{"v":4e-134,"d":"4.00E-134"},133.397940008672,"(EA)",0.481,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":5e-134,"d":"5.00E-134"},133.301029995663,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":3e-133,"d":"3.00E-133"},132.52287874528,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":6e-133,"d":"6.00E-133"},132.221848749616,null,8.76,"[7.98-9.54] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":7e-133,"d":"7.00E-133"},132.154901959985,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2E-132,"d":"2.00E-132"},131.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":6e-132,"d":"6.00E-132"},131.221848749616,{"$nulls":3},"NR [2501549] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":6e-131,"d":"6.00E-131"},130.221848749616,null,5.41,"[4.94-5.88] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":9e-131,"d":"9.00E-131"},130.04575749056,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,"NR",{"v":2e-130,"d":"2.00E-130"},129.698970004336,null,0.137,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":3e-130,"d":"3.00E-130"},129.52287874528,null,0.131,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-129,"d":"1.00E-129"},129,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":1e-129,"d":"1.00E-129"},129,"(Asian initial, BMI unadjusted)",0.523,"[0.48-0.56] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":2e-128,"d":"2.00E-128"},127.698970004336,null,0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":8e-128,"d":"8.00E-128"},127.096910013008,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":1E-127,"d":"1.00E-127"},127,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":2e-127,"d":"2.00E-127"},126.698970004336,null,0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":3e-126,"d":"3.00E-126"},125.52287874528,"(EA)",0.14,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":7E-126,"d":"7.00E-126"},125.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":1E-125,"d":"1.00E-125"},125,"(EA)",0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-?","rs261334",0,261334,"intron_variant",0,"NR",{"v":1E-125,"d":"1.00E-125"},125,"(Triglycerides in very large HDL, conditioned)",0.2686627,"[0.25-0.29] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41926126,"rs72836561","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","17q21.31","CD300LG","CD300LG",null,null,"ENSG00000161649",null,null,"rs72836561-T","rs72836561",0,72836561,"missense_variant",0,0.029,{"v":1e-123,"d":"1.00E-123"},123,null,0.1987,"[0.18-0.22] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,"NR",{"v":9e-123,"d":"9.00E-123"},122.04575749056,null,0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-122,"d":"8.00E-122"},121.096910013008,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-121,"d":"1.00E-121"},121,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":2E-121,"d":"2.00E-121"},120.698970004336,null,0.126,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-A","rs2954022",0,2954022,"intron_variant",0,0.47,{"v":7e-121,"d":"7.00E-121"},120.154901959985,"(Trans-ethnic initial)",0.078,"[0.072-0.084] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":8e-121,"d":"8.00E-121"},120.096910013008,null,0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-120,"d":"1.00E-120"},120,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06,{"v":2E-120,"d":"2.00E-120"},119.698970004336,"(Free cholesterol in large LDL)",0.59,"[0.53-0.65] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2E-120,"d":"2.00E-120"},119.698970004336,"(Selenoprotein S, VIMP.11286.78.3)",1.01,"[0.93-1.09] unit decrease","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-119,"d":"1.00E-119"},119,"(Quinone oxidoreductase-like protein 1, CRYZL1.9207.60.3)",1,"[0.92-1.08] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":3e-119,"d":"3.00E-119"},118.52287874528,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-118,"d":"1.00E-118"},118,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44081064,"rs8070723","2011-07-14",21685912,"Hoglinger GU","2011-06-19","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21685912","Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.","Progressive supranuclear palsy","1,069 European ancestry cases, 2,958 European ancestry controls, 45 cases, 329 controls","1,051 European ancestry cases, 3,560 European ancestry controls","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs8070723-?","rs8070723",0,8070723,"intron_variant",0,0.23,{"v":2E-118,"d":"2.00E-118"},117.698970004336,null,5.11,"[4.43-5.91]","Illumina [531451]","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":3e-118,"d":"3.00E-118"},117.52287874528,null,0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":4e-117,"d":"4.00E-117"},116.397940008672,null,6.99,"[6.4-7.58] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs562338",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":8e-117,"d":"8.00E-117"},116.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":8e-117,"d":"8.00E-117"},116.096910013008,null,0.089,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":2e-115,"d":"2.00E-115"},114.698970004336,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.12,{"v":2e-115,"d":"2.00E-115"},114.698970004336,null,13.64,"[12.37-14.91] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","up to 4,420 African ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,0.13,{"v":3e-115,"d":"3.00E-115"},114.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":5e-115,"d":"5.00E-115"},114.301029995663,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":2e-114,"d":"2.00E-114"},113.698970004336,"(Complement C1q tumor necrosis factor-related protein 1, C1QTNF1.6304.8.3)",0.64,"[0.58-0.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.3261,{"v":1e-113,"d":"1.00E-113"},113,null,0.26576465,"[0.24-0.29] mg/dl increase","Illumina [24111857] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":2E-113,"d":"2.00E-113"},112.698970004336,null,0.217,"[0.2-0.24] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":1e-112,"d":"1.00E-112"},112,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3e-112,"d":"3.00E-112"},111.52287874528,null,0.119,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63107526,"rs995000","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.3454,{"v":6e-112,"d":"6.00E-112"},111.221848749616,null,0.0618,"[0.056-0.067] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":3e-111,"d":"3.00E-111"},110.52287874528,null,0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.117,{"v":2e-110,"d":"2.00E-110"},109.698970004336,"(Trans-ethnic initial)",0.115,"[0.1-0.13] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":7e-110,"d":"7.00E-110"},109.154901959985,null,0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":2E-109,"d":"2.00E-109"},108.698970004336,null,0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":3e-109,"d":"3.00E-109"},108.52287874528,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-?","rs261291",0,261291,"intron_variant",0,"NR",{"v":7e-109,"d":"7.00E-109"},108.154901959985,null,0.1158,"[0.11-0.13] unit increase novel","Illumina [6108953] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,null,0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":1E-107,"d":"1.00E-107"},107,null,0.076,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.5747,{"v":4e-106,"d":"4.00E-106"},105.397940008672,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.879,{"v":5e-106,"d":"5.00E-106"},105.301029995663,"(EA)",0.127,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","RP11-115J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1054,{"v":1e-105,"d":"1.00E-105"},105,null,0.0954,"[0.087-0.104] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-04-30",28714976,"Sims R","2017-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714976","Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.","Alzheimer's disease (late onset)","up to 16,097 European ancestry cases, up to 18,077 European ancestry controls","up to 20,693 European ancestry cases, up to 30,266 European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-105,"d":"3.00E-105"},104.52287874528,null,2.3065467,null,"Illumina [241551]","N"]
[29,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,"NR",{"v":5e-105,"d":"5.00E-105"},104.301029995663,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,"NR",{"v":6e-105,"d":"6.00E-105"},104.221848749616,null,0.106,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":9e-105,"d":"9.00E-105"},104.04575749056,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.897,{"v":9e-104,"d":"9.00E-104"},103.04575749056,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,0.44,{"v":9e-104,"d":"9.00E-104"},103.04575749056,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs2074404",17,44800046,"rs7224296","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Balding type 1","approximately 208,000 European ancestry individuals","NA","17q21.31",null,"NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs7224296-?","rs7224296",0,7224296,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[17,"rs117026536",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.897,{"v":2e-103,"d":"2.00E-103"},102.698970004336,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,"NR",{"v":2e-102,"d":"2.00E-102"},101.698970004336,null,0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":6e-101,"d":"6.00E-101"},100.221848749616,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":8e-101,"d":"8.00E-101"},100.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":8e-101,"d":"8.00E-101"},100.096910013008,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":2E-100,"d":"2.00E-100"},99.698970004336,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.67,{"v":4e-100,"d":"4.00E-100"},99.397940008672,null,0.32,"[0.29-0.35] µg/mL increase","Illumina [NR] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":6e-100,"d":"6.00E-100"},99.2218487496163,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":7e-100,"d":"7.00E-100"},99.1549019599857,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.88,{"v":1E-99,"d":"1.00E-99"},99,"(EA)",0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.07994,{"v":1E-99,"d":"1.00E-99"},99,null,21.199877,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-99,"d":"1.00E-99"},99,"(Cardiotrophin-1, CTF1.13732.79.3)",0.92,"[0.84-1] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":2E-99,"d":"2.00E-99"},98.698970004336,"(EA)",0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":9e-99,"d":"9.00E-99"},98.0457574905606,null,0.115,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":3E-98,"d":"3.00E-98"},97.5228787452803,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44095467,"rs58879558","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs58879558-?","rs58879558",0,58879558,"intron_variant",0,"NR",{"v":3E-98,"d":"3.00E-98"},97.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":4e-98,"d":"4.00E-98"},97.397940008672,"(EA)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.12,{"v":1E-97,"d":"1.00E-97"},97,null,2.25,"[2.01-2.49] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs9939224",16,57002732,"rs9939224","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs9939224-?","rs9939224",0,9939224,"intron_variant",0,"NR",{"v":1E-97,"d":"1.00E-97"},97,null,0.1861,"[0.17-0.2] unit decrease novel","Illumina [6108953] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-97,"d":"1.00E-97"},97,"(Hemoglobin subunit theta-1, HBQ1.7965.25.3)",0.92,"[0.84-1] unit decrease","Affymetrix [10572788] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.896,{"v":2e-97,"d":"2.00E-97"},96.698970004336,"(EA)",0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.17,{"v":2e-97,"d":"2.00E-97"},96.698970004336,null,3.353,"[3.04-3.66] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-A","rs247617",0,247617,"regulatory_region_variant",1,0.3,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(Total cholesterol in HDL)",0.23,"[0.21-0.25] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":7e-97,"d":"7.00E-97"},96.1549019599857,null,7.09,"[6.42-7.76] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[15,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.809,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(EA)",0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":2e-96,"d":"2.00E-96"},95.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs201220977",10,65066186,"rs10761741","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.4176,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,null,0.07693902,"[0.07-0.084] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.39,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,null,1.45,"[1.29-1.61] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":6e-96,"d":"6.00E-96"},95.2218487496163,null,0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.81,{"v":2E-95,"d":"2.00E-95"},94.698970004336,"(EA)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-94,"d":"2.00E-94"},93.698970004336,null,0.08881,"[0.08-0.097] unit decrease novel","Illumina [6108953] (imputed)","N"]
[29,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0779,{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.41957754,"[0.38-0.46] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-94,"d":"6.00E-94"},93.2218487496163,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-C","rs1532624",0,1532624,"intron_variant",0,0.57,{"v":9e-94,"d":"9.00E-94"},93.0457574905606,null,0.21,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(HDL-C.assay, whole)",3.096,"[NR] unit increase","Illumina [335603]","N"]
[31,"rs3816117",16,56995236,"rs1800775","2009-12-29",20031564,"Ridker PM","2009-02-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031564","Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.","HDL cholesterol","18,245 European ancestry females","NA","16q13","SLC12A3, HERPUD1, CETP, NUP93","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.49,{"v":4e-93,"d":"4.00E-93"},92.397940008672,null,3.09,"mg/dL increase","Illumina [~ 318237]","N"]
[1,"rs11591147",1,55505647,"rs11591147","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.98,{"v":2E-92,"d":"2.00E-92"},91.698970004336,null,0.528,"[0.48-0.58] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2E-92,"d":"2.00E-92"},91.698970004336,"(C5orf38)",1.016853,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,63107526,"rs995000","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.309,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,"(Trans-ethnic initial)",0.0691,"[0.062-0.076] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,null,0.073,"[0.065-0.081] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":6e-92,"d":"6.00E-92"},91.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":7e-92,"d":"7.00E-92"},91.1549019599857,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,0.146,"[0.13-0.16] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":2E-91,"d":"2.00E-91"},90.698970004336,"(EA)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.09,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-91,"d":"4.00E-91"},90.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2E-90,"d":"2.00E-90"},89.698970004336,"(Ubiquitin carboxyl-terminal hydrolase 21, USP21.12681.63.3)",0.49,"[0.45-0.53] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-90,"d":"3.00E-90"},89.5228787452803,"(Inactive gamma-glutamyltranspeptidase 2, GGT2.6334.9.3)",0.88,"[0.8-0.96] unit decrease","Affymetrix [10572788] (imputed)","N"]
[15,"rs33951980",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":4E-90,"d":"4.00E-90"},89.397940008672,null,0.118,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.36,{"v":5e-88,"d":"5.00E-88"},87.3010299956639,null,0.123,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.892,{"v":1E-87,"d":"1.00E-87"},87,"(EA)",0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,{"$nulls":3},"NR [2501543] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3e-87,"d":"3.00E-87"},86.5228787452803,"(ARL2)",0.97562826,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":5e-87,"d":"5.00E-87"},86.3010299956639,"(HDL.large, whole)",0.729,"[NR] unit increase","Illumina [335603]","N"]
[29,"rs261291",15,58680178,"rs261291","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-C","rs261291",0,261291,"intron_variant",0,0.37,{"v":6e-87,"d":"6.00E-87"},86.2218487496163,null,0.122,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[2,"rs638714",1,63124465,"rs4495740","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs4495740-T","rs4495740",0,4495740,"intron_variant",0,0.6678,{"v":2e-86,"d":"2.00E-86"},85.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.4,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(BMI-adjusted)",0.077,"[0.069-0.085] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":3e-85,"d":"3.00E-85"},84.5228787452803,null,0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56991363,"rs183130","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,12588,4399,"rs183130-T","rs183130",0,183130,"intergenic_variant",1,0.3073,{"v":1E-84,"d":"1.00E-84"},84,null,0.0549,"[0.049-0.06] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.707,{"v":5e-84,"d":"5.00E-84"},83.3010299956639,"(EA)",0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.874,{"v":8e-84,"d":"8.00E-84"},83.096910013008,"(EA)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41926126,"rs72836561","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","17q21.31","CD300LG","CD300LG",null,null,"ENSG00000161649",null,null,"rs72836561-T","rs72836561",0,72836561,"missense_variant",0,0.0288,{"v":8e-84,"d":"8.00E-84"},83.096910013008,null,0.1636,"[0.15-0.18] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.89,{"v":9e-84,"d":"9.00E-84"},83.0457574905606,null,0.186,"[0.17-0.21] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[2,"rs638714",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.295,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,"(Trans-ethnic initial)",0.0758,"[0.069-0.083] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[18,"rs2954021",8,126478450,"rs2001846","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27803,731,"rs2001846-T","rs2001846",0,2001846,"intergenic_variant",1,0.4479,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,null,0.0539,"[0.048-0.059] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":1e-81,"d":"1.00E-81"},81,"(HDL-C.by.NMR, whole)",2.658,"[NR] unit increase","Illumina [335603]","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-81,"d":"4.00E-81"},80.397940008672,"(Guanine nucleotide-binding protein G(k) subunit alpha, GNAI3.12650.43.3)",0.84,"[0.76-0.92] unit increase","Affymetrix [10572788] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":5e-81,"d":"5.00E-81"},80.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-80,"d":"2.00E-80"},79.698970004336,"(CUZD1)",0.9441912,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":4e-80,"d":"4.00E-80"},79.397940008672,null,0.075,"[NR] unit decrease","NR [NR] (imputed)","N"]
[17,"rs117026536",8,19819328,"rs325","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs325-?","rs325",0,325,"intron_variant",0,"NR",{"v":2E-79,"d":"2.00E-79"},78.698970004336,null,0.1483,"[0.13-0.16] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-78,"d":"2.00E-78"},77.698970004336,"(women)",0.09,"[NR] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q21.3","ALDH1A2","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.3451,{"v":4E-78,"d":"4.00E-78"},77.397940008672,null,0.0522,"[0.047-0.058] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[34,"rs7225002",17,44189067,"rs7225002","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","17q21.31",null,"KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs7225002-?","rs7225002",0,7225002,"intron_variant",0,"NR",{"v":7e-78,"d":"7.00E-78"},77.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":8E-78,"d":"8.00E-78"},77.096910013008,"(HDL.mean.size, whole)",0.086,"[NR] unit increase","Illumina [335603]","N"]
[38,"rs7412",19,45412079,"rs7412","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06071,{"v":8E-78,"d":"8.00E-78"},77.096910013008,null,17.11,"[15.31-18.91] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-77,"d":"1.00E-77"},77,"(mannose)",0.044,"[0.04-0.048] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":1e-77,"d":"1.00E-77"},77,"(Trans-ethnic initial)",0.0622,"[0.055-0.069] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":4e-77,"d":"4.00E-77"},76.397940008672,null,0.137,"[NR] unit decrease","NR [NR] (imputed)","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":5e-77,"d":"5.00E-77"},76.3010299956639,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-76,"d":"2.00E-76"},75.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[29,"rs261291",15,58680643,"rs35853021","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs35853021-?","rs35853021",0,35853021,"intron_variant",0,"NR",{"v":7e-76,"d":"7.00E-76"},75.1549019599857,"(XL-HDL-TG)",0.31,"[0.27-0.35] unit increase","Illumina [~ 7700000] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-T","rs173539",0,173539,"intergenic_variant",1,0.32,{"v":4e-75,"d":"4.00E-75"},74.397940008672,null,0.25,"[0.21-0.29] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5e-75,"d":"5.00E-75"},74.3010299956639,"(Trans-ethnic initial)",0.137,"[0.12-0.15] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.169,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Asian initial, BMI unadjusted)",0.262,"[0.23-0.29] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs9304381",18,47181668,"rs2156552","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.178,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Trans-ethnic initial)",0.0793,"[0.07-0.088] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.066,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-A","rs12720922",0,12720922,"intron_variant",0,0.17,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.35,"[0.31-0.39] µg/mL increase","Illumina [NR] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,"(Collectin-10, COLEC10.6558.5.3)",0.81,"[0.73-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.981,{"v":6e-74,"d":"6.00E-74"},73.2218487496163,"(EA)",0.347,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.51,{"v":1E-73,"d":"1.00E-73"},73,null,0.18,"[0.16-0.20] unit decrease","Affymetrix [389878]","N"]
[35,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":3e-73,"d":"3.00E-73"},72.5228787452803,null,0.2326,"[0.21-0.26] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.0692,{"v":3e-72,"d":"3.00E-72"},71.5228787452803,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs190921611",19,45452812,"rs1130742","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC2, APOC4-APOC2",null,null,"ENSG00000234906, ENSG00000224916",null,null,"rs1130742-T","rs1130742",0,1130742,"3_prime_UTR_variant",0,0.261,{"v":5e-72,"d":"5.00E-72"},71.3010299956639,"(PH and SEC7 domain-containing protein 2, PSD2.9118.7.3)",0.49,"[0.43-0.55] unit decrease","Affymetrix [10572788] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5E-71,"d":"5.00E-71"},70.3010299956639,"(Trans-ethnic initial)",0.121,"[0.11-0.13] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-70,"d":"3.00E-70"},69.5228787452803,null,0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-?","rs173539",0,173539,"intergenic_variant",1,0.28,{"v":3e-70,"d":"3.00E-70"},69.5228787452803,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":6e-70,"d":"6.00E-70"},69.2218487496163,"(EA)",0.475,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":7e-70,"d":"7.00E-70"},69.1549019599857,"(CEP57)",0.89456034,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":1e-69,"d":"1.00E-69"},69,null,0.121,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC4, APOC4-APOC2, APOC2, CTB-129P6.11","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.3510532,{"v":2e-69,"d":"2.00E-69"},68.698970004336,"(EA, Granulocyte colony-stimulating factor)",0.7496,"[0.67-0.83] unit increase","Affymetrix [509946]","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":6e-69,"d":"6.00E-69"},68.2218487496163,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43994648,"rs17649553","2017-10-24",28892059,"Chang D","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892059","A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.","Parkinson's disease","20,184 European ancestry cases, 397,324 European ancestry controls","5,851 European ancestry cases, 5,866 European ancestry controls","17q21.31","ARHGAP27, CRHR1, KANSL1, SPPL2C, MAPT, STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17649553-C","rs17649553",0,17649553,"intron_variant",0,0.779,{"v":1e-68,"d":"1.00E-68"},68,null,1.2820514,"[1.25-1.32]","Illumina [11933700] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.701,{"v":3E-68,"d":"3.00E-68"},67.5228787452803,"(Hispanic)",0.235,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.695,{"v":1e-67,"d":"1.00E-67"},67,"(Hispanic)",0.233,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15129459,"rs4985155","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)","8,631 European ancestry individuals","NA","16p13.11","PDXDC1, NTAN1, C16orf45, KIAA0430, MYH11, NDEI, RRN3, PARN","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.648,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.22,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.7,{"v":2e-67,"d":"2.00E-67"},66.698970004336,"(Hispanic)",0.234,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":1e-66,"d":"1.00E-66"},66,"(HDL-C.assay, fasting)",3.094,"[NR] unit increase","Illumina [335603]","N"]
[18,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.062,"[NR] unit decrease","NR [NR] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-T","rs173539",0,173539,"intergenic_variant",1,0.32,{"v":3E-65,"d":"3.00E-65"},64.5228787452803,"(HDL)",0.255,"[0.23-0.28] mmol/l increase","Illumina [NR] (imputed)","N"]
[22,"rs55891451",10,96734676,"rs1934963","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","10q23.33","CYP2C9","CYP2C9",null,null,"ENSG00000138109",null,null,"rs1934963-T","rs1934963",0,1934963,"intron_variant",0,0.8,{"v":9e-65,"d":"9.00E-65"},64.0457574905606,"(X-11787)",0.029,"[0.025-0.033] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,null,0.12,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[7,"rs11681659",2,136616754,"rs182549","2017-09-05",28588231,"Li M","2017-06-06","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28588231","Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.","1,5-anhydroglucitol levels","7,550 European ancestry individuals","8,790 European ancestry individuals, 2,030 African American individuals","2q21.3","MCM6/LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs182549-C","rs182549",0,182549,"intron_variant",0,0.33,{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(EA)",16.91,"z-score decrease","Affymetrix [at least 8500000] (imputed)","N"]
[7,"rs11681659",2,136616754,"rs182549","2017-09-05",28588231,"Li M","2017-06-06","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28588231","Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.","1,5-anhydroglucitol levels","7,550 European ancestry individuals","8,790 European ancestry individuals, 2,030 African American individuals","2q21.3","MCM6/LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs182549-C","rs182549",0,182549,"intron_variant",0,"NR",{"v":4e-64,"d":"4.00E-64"},63.397940008672,null,16.91,"z-score decrease","Affymetrix [at least 8500000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":6e-64,"d":"6.00E-64"},63.2218487496163,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.711,{"v":6e-64,"d":"6.00E-64"},63.2218487496163,"(Hispanic)",0.23,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-C","rs515135",0,515135,"intergenic_variant",1,0.83,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.135,"[0.12-0.15] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1012,{"v":2e-63,"d":"2.00E-63"},62.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.11,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.162,"[0.14-0.18] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [2501549] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-63,"d":"3.00E-63"},62.5228787452803,"(Mediator of RNA polymerase II transcription subunit 4, MED4.14021.81.3)",0.42,"[0.38-0.46] unit increase","Affymetrix [10572788] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":4e-63,"d":"4.00E-63"},62.397940008672,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.733,{"v":7e-63,"d":"7.00E-63"},62.1549019599857,"(Hispanic)",0.244,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.69,{"v":1E-62,"d":"1.00E-62"},62,"(Hispanic)",0.222,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-04-12",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Free cholesterol levels in large LDL","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.642,"unit decrease","Illumina [15144991] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-62,"d":"2.00E-62"},61.698970004336,"(S100A13)",0.82494706,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":9e-62,"d":"9.00E-62"},61.0457574905606,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":3e-61,"d":"3.00E-61"},60.5228787452803,"(Free cholesterol in large LDL, conditioned)",0.5335034,"[0.47-0.60] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.709,{"v":5e-61,"d":"5.00E-61"},60.3010299956639,"(Hispanic)",0.226,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":1e-60,"d":"1.00E-60"},60,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs11407273",11,61639573,"rs174448","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS3","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,"NR",{"v":3e-60,"d":"3.00E-60"},59.5228787452803,null,0.05,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":4e-60,"d":"4.00E-60"},59.397940008672,"(RAC-beta serine/threonine-protein kinase, AKT2.14685.17.3)",0.73,"[0.65-0.81] unit decrease","Affymetrix [10572788] (imputed)","N"]
[17,"rs117026536",8,19820433,"rs12679834","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8p21.3",null,"LPL",null,null,"ENSG00000175445",null,null,"rs12679834-?","rs12679834",0,12679834,"intron_variant",0,"NR",{"v":9E-60,"d":"9.00E-60"},59.0457574905606,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.72,{"v":9E-60,"d":"9.00E-60"},59.0457574905606,"(HDL)",0.25,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[3,"rs629301",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2346,{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.112,"[0.098-0.126] unit decrease","NR [8041861] (imputed)","N"]
[23,"rs198435",11,61442492,"rs7925523","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","AP002754.2 - DAGLA","ENSG00000255947","ENSG00000134780",null,19318,5413,"rs7925523-G","rs7925523",0,7925523,"intergenic_variant",1,0.7873,{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.3969,"[0.35-0.44] unit decrease","Illumina [up to 1980188] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":2e-59,"d":"2.00E-59"},58.698970004336,"(HDL.large, fasting)",0.703,"[NR] unit increase","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-59,"d":"4.00E-59"},58.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","19q13.32","APOE, APOC1, APOC2","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(BMI unadjusted)",0.568,"[0.5-0.64] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-G","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.19,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,null,7.91,"[6.93-8.89] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.952,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,"(Hispanic)",0.574,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(Cell surface glycoprotein CD200 receptor 2, CD200R1L.8980.19.3)",0.72,"[0.64-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(Apolipoprotein E (isoform E3), APOE.2937.10.2)",0.72,"[0.64-0.8] unit decrease","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-58,"d":"3.00E-58"},57.5228787452803,"(L-LDL-FC)",0.75,"[0.65-0.85] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[3,"rs629301",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2343,{"v":4e-58,"d":"4.00E-58"},57.397940008672,null,0.0999,"[0.088-0.112] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","1p13.3","CELSR2, PSRC1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.219,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.124,"[0.11-0.14] unit decrease","Affymetrix [7947838] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":2e-57,"d":"2.00E-57"},56.698970004336,"(EA)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.31,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,3.47,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[35,"rs9304381",18,47158234,"rs9304381","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32682,18486,"rs9304381-T","rs9304381",0,9304381,"intergenic_variant",1,0.8098,{"v":1E-56,"d":"1.00E-56"},56,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","19q13.32","APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-T","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.11,{"v":1E-56,"d":"1.00E-56"},56,"(activity)",0.071,"[0.049-0.093] ng/ml decrease","Illumina [796174]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131705458,"rs2631367","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","5q31.1",null,"SLC22A5, MIR3936HG",null,null,"ENSG00000197375, ENSG00000233006",null,null,"rs2631367-?","rs2631367",0,2631367,"5_prime_UTR_variant",0,"NR",{"v":2e-56,"d":"2.00E-56"},55.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(Trans-ethnic initial)",0.0564,"[0.049-0.063] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.789,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(Trans-ethnic initial)",0.0652,"[0.057-0.074] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.937,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(APOE)",0.795,"[0.7-0.89] unit increase","Illumina [> 1000000] (imputed)","N"]
[21,"rs7924036",10,65154885,"rs10761751","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","10q21.3",null,"JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761751-?","rs10761751",0,10761751,"intron_variant",0,"NR",{"v":4e-56,"d":"4.00E-56"},55.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":5E-56,"d":"5.00E-56"},55.3010299956639,"(EA)",0.413,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-02-05",25898920,"Korostishevsky M","2015-04-22","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/25898920","Genomics and metabolomics of muscular mass in a community-based sample of UK females.","Blood metabolite levels","3,953 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-56,"d":"6.00E-56"},55.2218487496163,"(Mannose levels)",null,null,"Illumina [2300000]","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":8e-56,"d":"8.00E-56"},55.096910013008,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,5.64,"[4.88-6.4] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":3e-55,"d":"3.00E-55"},54.5228787452803,"(HDL-C.by.NMR, fasting)",2.608,"[NR] unit increase","Illumina [335603]","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":2e-54,"d":"2.00E-54"},53.698970004336,null,0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.118,"[NR] unit decrease","NR [NR] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,null,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.1615,"[0.14-0.18] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1E-53,"d":"1.00E-53"},53,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":1E-53,"d":"1.00E-53"},53,"(HDL.mean.size, fasting)",0.084,"[NR] unit increase","Illumina [335603]","N"]
[34,"rs16940904",17,44083402,"rs1991556","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FVC)","approximately 372,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1991556-?","rs1991556",0,1991556,"intron_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-53,"d":"2.00E-53"},52.698970004336,"(APOB.assay, whole)",5.205,"[NR] unit decrease","Illumina [335603]","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.12,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(LDL-C)",0.48,"[0.42-0.54] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":4e-53,"d":"4.00E-53"},52.397940008672,null,0.05965,"[0.052-0.067] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.399,{"v":6e-53,"d":"6.00E-53"},52.2218487496163,"(glucose/mannose + 54 other traits)",0.101,"[NR] unit increase","Affymetrix, Illumina [534665]","N"]
[3,"rs629301",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":1E-52,"d":"1.00E-52"},52,"(Granulins)",0.7583,"[0.67-0.85] unit decrease","Affymetrix [509946]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3929,{"v":1E-52,"d":"1.00E-52"},52,null,0.034923363,"[0.03-0.039] unit decrease","Affymetrix [11514936] (imputed)","N"]
[36,"rs2278426",19,11350488,"rs2278426","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","C19orf80","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-T","rs2278426",0,2278426,"missense_variant",0,0.1249,{"v":1E-52,"d":"1.00E-52"},52,null,0.0756,"[0.066-0.085] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.076340503,{"v":1E-52,"d":"1.00E-52"},52,"(APOB)",0.5368132,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.08,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":6E-52,"d":"6.00E-52"},51.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":1E-51,"d":"1.00E-51"},51,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs111784051",19,45389596,"rs7254892","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","NECTIN2, AC011481.2",null,null,"ENSG00000130202, ENSG00000267114",null,null,"rs7254892-A","rs7254892",0,7254892,"intron_variant",0,0.07,{"v":1E-51,"d":"1.00E-51"},51,"(Asian initial, BMI unadjusted)",0.4,"[0.35-0.45] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[36,"rs151113958",19,11202306,"rs6511720","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.26,"[0.22-0.30] unit decrease","Affymetrix [389878]","N"]
[2,"rs638714",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs272863",5,131665378,"rs272889","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272889-A","rs272889",0,272889,"intron_variant",0,0.37,{"v":3E-51,"d":"3.00E-51"},50.5228787452803,"(valine/isovalerylcarnitine)",0.039,"[0.033-0.045] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[21,"rs201220977",10,65101207,"rs10740118","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet distribution width","164,433 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10740118-C","rs10740118",0,10740118,"intron_variant",0,0.419,{"v":3E-51,"d":"3.00E-51"},50.5228787452803,null,0.05482214,"[0.048-0.062] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":5E-51,"d":"5.00E-51"},50.3010299956639,null,0.247,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.06402,"[0.056-0.072] unit increase novel","Illumina [6108953] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":6E-51,"d":"6.00E-51"},50.2218487496163,"(Trans-ethnic initial)",0.118,"[0.1-0.13] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":8e-51,"d":"8.00E-51"},50.096910013008,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2E-50,"d":"2.00E-50"},49.698970004336,null,0.056,"[NR] unit decrease","NR [NR] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Total cholesterol levels in LDL","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-50,"d":"5.00E-50"},49.3010299956639,null,0.573,"unit decrease","Illumina [15144991] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2018-01-08",29186428,"Tonjes A","2017-11-27","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/29186428","Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin.","Progranulin levels","1,963 European ancestry individuals, 848 Sorbian (founder/genetic isolate) individuals","1800 European ancestry individuals","1p13.3","CELSR2, PSRC1, MYBPHL, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-C","rs660240",0,660240,"3_prime_UTR_variant",0,0.784,{"v":6e-50,"d":"6.00E-50"},49.2218487496163,null,0.169,"unit increase","Affymetrix [2069113] (imputed)","N"]
[35,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,"NR",{"v":7e-50,"d":"7.00E-50"},49.1549019599857,null,0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,{"$nulls":3},"Affymetrix [NR]","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8p23.1","LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,0.124,"[0.1-0.14] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[15,"rs138574868",7,73023881,"rs12531645","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL, AC005089.1",null,null,"ENSG00000009950, ENSG00000274080",null,null,"rs12531645-?","rs12531645",0,12531645,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,0.1056,"[0.092-0.12] unit decrease novel","Illumina [6108953] (imputed)","N"]
[34,"rs16940904",17,43940021,"rs79412431","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","FEV1","321,047 European ancestry individuals","79,005 European ancestry individuals","17q21.31","MAPT-AS1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs79412431-A","rs79412431",0,79412431,"intron_variant",0,0.2161,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,0.0426,"[0.037-0.048] unit decrease","Affymetrix [19819130] (imputed)","N"]
[35,"rs9304381",18,47160953,"rs7241918","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.17,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,1.31,"[1.11-1.51] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","HDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.773,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(Hispanic)",0.243,"[0.21-0.27] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[23,"rs61896141",11,61595564,"rs968567","2019-04-24",30453627,"Marklund M","2018-11-17","Nutrients","www.ncbi.nlm.nih.gov/pubmed/30453627","Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity.","Fatty acid desaturase activity (serum)","1,453 European ancestry individuals","NA","11q12.2","FADS2, FADS1, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-T","rs968567",0,968567,"5_prime_UTR_variant",0,0.15,{"v":5e-49,"d":"5.00E-49"},48.3010299956639,"(D5D)",null,null,"Illumina [at least 738879] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.794,{"v":6E-49,"d":"6.00E-49"},48.2218487496163,"(Hispanic)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294715,"rs4846913","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","1q42.13",null,"GALNT2",null,null,"ENSG00000143641",null,null,"rs4846913-?","rs4846913",0,4846913,"intron_variant",0,"NR",{"v":1e-48,"d":"1.00E-48"},48,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.06015,"[0.052-0.068] unit decrease novel","Illumina [6108953] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":1e-48,"d":"1.00E-48"},48,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2010-09-13",20694148,"Zabaneh D","2010-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20694148","A genome-wide association study of the metabolic syndrome in Indian Asian men.","Metabolic syndrome","2,554 Indian Asian ancestry individuals","2,240 Indian Asian ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.36,{"v":1e-48,"d":"1.00E-48"},48,"(HDL)",0.07,"[0.06-0.08] mmol/l increase","Illumina [308011]","N"]
[34,"rs16940904",17,43994648,"rs17649553","2015-05-09",25064009,"Nalls MA","2014-07-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25064009","Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.","Parkinson's disease","13,708 European ancestry cases, 95,282 European ancestry controls","5,353 European ancestry cases, 5,551 European ancestry controls","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17649553-C","rs17649553",0,17649553,"intron_variant",0,0.774,{"v":2e-48,"d":"2.00E-48"},47.698970004336,null,1.3,"[1.27-1.34]","Illumina [7893274] (imputed)","N"]
[35,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.987,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3e-48,"d":"3.00E-48"},47.5228787452803,"(Il16)",0.7322723,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[3,"rs629301",1,109821797,"rs4970836","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3425,381,"rs4970836-A","rs4970836",0,4970836,"intergenic_variant",1,0.771,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(Group XIIB secretory phospholipase A2-like protein, PLA2G12B.9380.2.3)",0.42,"[0.36-0.48] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-A","rs4846914",0,4846914,"intron_variant",0,0.5456,{"v":4e-48,"d":"4.00E-48"},47.397940008672,null,0.0409,"[0.035-0.046] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.828,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(East Asian)",0.256,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.829,{"v":7e-48,"d":"7.00E-48"},47.1549019599857,"(East Asian)",0.254,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.821,{"v":9e-48,"d":"9.00E-48"},47.0457574905606,"(East Asian)",0.258,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.109,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.08,"[0.068-0.092] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.828,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(East Asian)",0.254,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2012-03-14",22331829,"Chasman DI","2012-02-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22331829","Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.","Response to statins (LDL cholesterol change)","6,989 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(baseline LDL-C)",6.2,"[5.42-6.98] mg/dL decrease","Illumina [814418]","N"]
[6,"rs1260326",2,27742603,"rs780093","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.413,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Trans-ethnic initial)",0.0515,"[0.044-0.059] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.086,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.628,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,"(Hispanic)",0.184,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.054,"[NR] unit increase","NR [NR] (imputed)","N"]
[36,"rs151113958",19,11190652,"rs142130958","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,550,9386,"rs142130958-A","rs142130958",0,142130958,"intergenic_variant",1,0.11,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,"(Free cholesterol in large LDL)",0.24,"[0.2-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":1E-46,"d":"1.00E-46"},46,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1E-46,"d":"1.00E-46"},46,"(CRYZL1)",0.7133005,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":2E-46,"d":"2.00E-46"},45.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.826,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(East Asian)",0.249,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43940021,"rs79412431","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","Lung function (FVC)","321,047 European ancestry individuals","79,005 European ancestry individuals","17q21.31","MAPT-AS1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs79412431-A","rs79412431",0,79412431,"intron_variant",0,0.2161,{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.0415,"[0.036-0.047] unit decrease","Affymetrix [19819130] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11882123",19,19475088,"rs2965199","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,5524,21547,"rs2965199-?","rs2965199",0,2965199,"intergenic_variant",1,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,"NR",{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":8e-45,"d":"8.00E-45"},44.096910013008,null,0.020889835,"[0.018-0.024] unit increase","NR [~ 10000000] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-A","rs7570971",0,7570971,"intron_variant",0,0.33,{"v":8e-45,"d":"8.00E-45"},44.096910013008,"(1,5-anhydroglucitol (1,5-AG))",0.037,"[0.031-0.043] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.793,{"v":8e-45,"d":"8.00E-45"},44.096910013008,"(Hispanic)",0.214,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-03-15",23263486,"Kottgen A","2012-12-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23263486","Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.","Urate levels","49,825 European ancestry males, 60,522 European ancestry females","Up to 32,813 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-44,"d":"1.00E-44"},44,null,0.074,"[0.063-0.084] mg/dl increase","Affymetrix, Illumina, Perlegen [2450547] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-A","rs247617",0,247617,"regulatory_region_variant",1,0.262,{"v":1e-44,"d":"1.00E-44"},44,"(AA)",0.0619,"[NR] unit increase","Affymetrix [NR]","N"]
[35,"rs9304381",18,47160953,"rs7241918","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.19,{"v":1e-44,"d":"1.00E-44"},44,null,0.09,"[NR] unit decrease","NR [NR] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-44,"d":"1.00E-44"},44,null,0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.01,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.47,"[0.41-0.53] unit decrease","Affymetrix [389878]","N"]
[2,"rs638714",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":2e-44,"d":"2.00E-44"},43.698970004336,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-A","rs4846914",0,4846914,"intron_variant",0,0.584,{"v":2e-44,"d":"2.00E-44"},43.698970004336,"(Trans-ethnic initial)",0.0479,"[0.041-0.055] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[21,"rs201220977",10,65050659,"rs7075195","2015-05-05",22139419,"Gieger C","2011-11-30","Nature","www.ncbi.nlm.nih.gov/pubmed/22139419","New gene functions in megakaryopoiesis and platelet formation.","Mean platelet volume","13,106 European ancestry individuals, 1,652 Val Borbera (founder/genetic isolate) individuals, 593 Carlantino (founder/genetic isolate) individuals, 1,146 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,213 South Tyrolean (founder/genetic isolate) individuals, 890 Sorbian (founder/genetic isolate) individuals","Up to 16,960 European ancestry individuals, 855 Cliento (founder/genetic isolate) individuals, 1,023 Talana (founder/genetic isolate) individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7075195-A","rs7075195",0,7075195,"intron_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.014,"[0.012-0.016] ln(fl) increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0793,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.08988161,"[0.077-0.102] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.0187927,"[0.016-0.021] unit increase","NR [~ 9732723] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":6e-44,"d":"6.00E-44"},43.2218487496163,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-43,"d":"1.00E-43"},43,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs149580368","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs149580368-C","rs149580368",1,112259268,"intergenic_variant",1,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.159,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.392,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,"(East Asian)",0.201,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":4e-43,"d":"4.00E-43"},42.397940008672,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-43,"d":"4.00E-43"},42.397940008672,"(Cofilin-1, CFL1.4203.50.2)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[28,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,"NR",{"v":5e-43,"d":"5.00E-43"},42.3010299956639,null,0.16,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-43,"d":"6.00E-43"},42.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,null,0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-?","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(levels)",0,"[0.80-4.70] % increase","Illumina [NR] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.35,{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(Indian)",3.18,"[2.73-3.63] unit increase","Illumina [551825]","N"]
[2,"rs638714",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.674,{"v":8e-43,"d":"8.00E-43"},42.096910013008,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19847690,"rs10503669","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-T","rs10503669",0,10503669,"intergenic_variant",1,0.12,{"v":8e-43,"d":"8.00E-43"},42.096910013008,null,0.0426,"[0.037-0.049] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":9e-43,"d":"9.00E-43"},42.0457574905606,null,4.94,"[4.16-5.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[16,"rs9987289",8,9184231,"rs4240624","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-A","rs4240624",0,4240624,"intron_variant",0,0.925,{"v":1E-42,"d":"1.00E-42"},42,"(Trans-ethnic initial)",0.0818,"[0.07-0.093] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":1E-42,"d":"1.00E-42"},42,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.21,{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.23,"[0.19-0.27] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41840849,"rs77697917","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-C","rs77697917",0,77697917,"intergenic_variant",1,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.154,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-42,"d":"3.00E-42"},41.5228787452803,null,0.051,"[NR] unit increase","NR [NR] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.399,{"v":4e-42,"d":"4.00E-42"},41.397940008672,"(East Asian)",0.197,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58727325,"rs261332","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-?","rs261332",0,261332,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-42,"d":"4.00E-42"},41.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[38,"rs7412",19,45415640,"rs445925","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","19q13.32","APOEC1, APOEC2, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-?","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.06,{"v":6e-42,"d":"6.00E-42"},41.2218487496163,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":7e-42,"d":"7.00E-42"},41.1549019599857,null,0.05782,"[0.049-0.066] unit decrease novel","Illumina [6108953] (imputed)","N"]
[37,"rs73001020",19,19394368,"rs138295924","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.11","SUGP1","SUGP1",null,null,"ENSG00000105705",null,null,"rs138295924-A","rs138295924",0,138295924,"intron_variant",0,0.9553,{"v":8e-42,"d":"8.00E-42"},41.096910013008,null,0.098,"[0.084-0.112] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs33924196",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7182,{"v":1E-41,"d":"1.00E-41"},41,null,0.041,"[0.035-0.047] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.35,{"v":1E-41,"d":"1.00E-41"},41,"(Hispanic)",0.188,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,"NR",{"v":1E-41,"d":"1.00E-41"},41,null,0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4253,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,6.8761177,"[5.88-7.88] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131652529,"rs11950562","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs11950562-A","rs11950562",0,11950562,"intron_variant",0,0.52,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(isovalerylcarnitine)",0.036,"[0.03-0.042] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.082,"[NR] unit decrease","NR [NR] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.1065,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,4.9720945,"[4.25-5.7] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.1,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.25,"[0.19-0.31] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.857,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(East Asian)",0.267,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-G","rs821840",0,821840,"regulatory_region_variant",1,0.168,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.0656,"[0.056-0.075] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(PSME1)",0.66324866,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":3e-41,"d":"3.00E-41"},40.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,0.41,{"v":4E-41,"d":"4.00E-41"},40.397940008672,null,0.048,"[NR] unit decrease","NR [NR] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs149580368","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs149580368-C","rs149580368",1,112259268,"intergenic_variant",1,0.973,{"v":4E-41,"d":"4.00E-41"},40.397940008672,"(EA)",0.158,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,2.6,"[2.21-2.99] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.117,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.136,"[0.12-0.16] unit decrease","Affymetrix [7947838] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1167,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.1359,"[0.12-0.16] unit decrease","NR [8041861] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":8E-41,"d":"8.00E-41"},40.096910013008,"(Furin, FURIN.6276.16.3)",0.34,"[0.28-0.4] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"rs11122450",1,230297136,"rs2281721","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2281721-T","rs2281721",0,2281721,"intron_variant",0,0.5522,{"v":1e-40,"d":"1.00E-40"},40,null,0.0377,"[0.032-0.043] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum albumin level","102,223 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.05949,"[0.051-0.068] unit decrease","Illumina [6108953] (imputed)","N"]
[15,"rs62466318",7,72999105,"rs9638182","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.81,{"v":1e-40,"d":"1.00E-40"},40,null,0.1,"[0.084-0.116] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[35,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.059,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,72877166,"rs2074755","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2074755-?","rs2074755",0,2074755,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-40,"d":"3.00E-40"},39.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-40,"d":"5.00E-40"},39.3010299956639,null,0.072,"[0.06-0.08] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"NR [2501543] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":1e-39,"d":"1.00E-39"},39,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.355,{"v":1e-39,"d":"1.00E-39"},39,"(Hispanic)",0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,"(APOA1.assay, fasting)",3.92,"[NR] unit increase","Illumina [335603]","N"]
[35,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":1e-39,"d":"1.00E-39"},39,null,0.1674,"[0.14-0.19] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-39,"d":"1.00E-39"},39,"(Cytoskeleton-associated protein 2, CKAP2.5345.51.3)",0.6,"[0.5-0.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.586,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(Asian initial, BMI unadjusted)",0.133,"[0.11-0.15] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[33,"rs72836561",17,41840849,"rs77697917","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-C","rs77697917",0,77697917,"intergenic_variant",1,0.972,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(EA)",0.152,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.08,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,null,0.16,"[0.14-0.18] unit decrease","Affymetrix [7947838] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0799,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,null,0.1603,"[0.14-0.18] unit decrease","NR [8041861] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,"(Endothelial monocyte-activating polypeptide 2, AIMP1.2714.78.2)",0.33,"[0.27-0.39] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.17646,{"v":4e-39,"d":"4.00E-39"},38.397940008672,null,7.44,"[6.32-8.56] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-39,"d":"4.00E-39"},38.397940008672,"(APOB.assay, fasting)",5.251,"[NR] unit decrease","Illumina [335603]","N"]
[17,"rs117026536",8,19832646,"rs17482753","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.1065,{"v":6e-39,"d":"6.00E-39"},38.2218487496163,null,10.830257,"[9.2-12.46] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.053,"[0.045-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs117026536",8,19847690,"rs10503669","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-T","rs10503669",0,10503669,"intergenic_variant",1,0.12,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.0857,"[0.073-0.098] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[31,"rs1864163",16,56997233,"rs1864163","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1864163-G","rs1864163",0,1864163,"intron_variant",0,0.8,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,4.12,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,"(Histone-lysine N-methyltransferase 2C, KMT2C.11402.17.3)",0.59,"[0.49-0.69] unit increase","Affymetrix [10572788] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":1e-38,"d":"1.00E-38"},38,null,0.08,"[0.068-0.092] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-38,"d":"1.00E-38"},38,"(Protocadherin beta-10, PCDHB10.9963.19.3)",0.59,"[0.49-0.69] unit decrease","Affymetrix [10572788] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,null,4.74,"[3.92-5.56] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,null,0.08416118,"[0.071-0.097] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Immature fraction of reticulocytes","170,548 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":4e-38,"d":"4.00E-38"},37.397940008672,null,0.08313494,"[0.071-0.096] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,43896032,"rs62057107","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (MTAG)","1,311,438 European ancestry individuals","NA","17q21.31","Intergenic","MAPT-AS1, MAPT-AS1, MAPT-AS1, CRHR1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000278232, ENSG00000263715, ENSG00000282456",null,null,"rs62057107-T","rs62057107",0,62057107,"intron_variant",0,0.2192,{"v":5e-38,"d":"5.00E-38"},37.3010299956639,"(MTAG)",0.0209,"[0.018-0.024] unit decrease","Affymetrix, Illumina [7100000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2010-02-28",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Fasting blood glucose","46,186 European ancestry individuals","76,558 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":6e-38,"d":"6.00E-38"},37.2218487496163,null,0.029,"[0.023-0.035] mmol/L increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.925,{"v":7e-38,"d":"7.00E-38"},37.1549019599857,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":8e-38,"d":"8.00E-38"},37.096910013008,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-38,"d":"8.00E-38"},37.096910013008,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs35717353",15,58577777,"rs12903590","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12903590-?","rs12903590",0,12903590,"intron_variant",0,"NR",{"v":9e-38,"d":"9.00E-38"},37.0457574905606,null,0.06743,"[0.057-0.078] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,"(TG.assay, whole)",0.07,"[NR] unit increase","Illumina [335603]","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126485294,"rs2954027","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954027-A","rs2954027",0,2954027,"intron_variant",0,0.4663,{"v":2e-37,"d":"2.00E-37"},36.698970004336,null,0.04543718,"[0.038-0.052] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.164,{"v":2e-37,"d":"2.00E-37"},36.698970004336,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3E-37,"d":"3.00E-37"},36.5228787452803,"(VIMP)",0.62421465,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs149580368","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs149580368-C","rs149580368",1,112259268,"intergenic_variant",1,"NR",{"v":4e-37,"d":"4.00E-37"},36.397940008672,null,0.16,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.163,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.168,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.927,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs7357361",8,9219887,"rs34597048","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8p23.1",null,"AC022784.1",null,null,"ENSG00000248538",null,null,"rs34597048-?","rs34597048",0,34597048,"intron_variant",0,"NR",{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.0455021,"[0.038-0.053] unit decrease","Affymetrix [20259828] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,0.17,{"v":5e-37,"d":"5.00E-37"},36.3010299956639,"(EA)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs13329672",15,58699937,"rs13329672","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-?","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":7e-37,"d":"7.00E-37"},36.1549019599857,null,0.0965,"[0.082-0.111] unit increase novel","Illumina [6108953] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.897,{"v":1e-36,"d":"1.00E-36"},36,"(Asian initial, BMI unadjusted)",0.163,"[0.14-0.19] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-?","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":1e-36,"d":"1.00E-36"},36,"(HDL-C)",0.22,"[0.18-0.26] unit increase","Illumina [~ 7700000] (imputed)","N"]
[35,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,0.164,{"v":1e-36,"d":"1.00E-36"},36,"(EA)",0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,0.084,"[NR] unit decrease","NR [NR] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,0.97,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(EA)",0.155,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11188153,"rs55791371","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs55791371-A","rs55791371",0,55791371,"intron_variant",0,0.8868,{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,0.1157,"[0.098-0.134] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(Amyloid beta A4 precursor protein-binding family B member 2, APBB2.12753.6.3)",0.57,"[0.47-0.67] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.892,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(AA)",0.522,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs7012637",8,9173209,"rs7012637","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs7012637-A","rs7012637",0,7012637,"intron_variant",0,0.47,{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.054,"[0.046-0.062] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43919096,"rs2106786","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","17q21.31","SPPL2C","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs2106786-G","rs2106786",0,2106786,"non_coding_transcript_exon_variant",0,0.2242,{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.0537452,"[0.045-0.062] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.294,{"v":4e-36,"d":"4.00E-36"},35.397940008672,"(Trans-ethnic initial)",0.0503,"[0.042-0.058] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.46,{"v":5E-36,"d":"5.00E-36"},35.3010299956639,null,2.3,"[1.93-2.67] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":5E-36,"d":"5.00E-36"},35.3010299956639,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-36,"d":"6.00E-36"},35.2218487496163,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":7e-36,"d":"7.00E-36"},35.1549019599857,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47158186,"rs10438978","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-C","rs10438978",0,10438978,"intergenic_variant",1,0.81,{"v":8e-36,"d":"8.00E-36"},35.096910013008,null,0.095,"[0.079-0.111] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,0.969,{"v":1E-35,"d":"1.00E-35"},35,"(EA)",0.151,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":1E-35,"d":"1.00E-35"},35,null,0.13,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[37,"rs58542926",19,19329924,"rs2228603","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2228603-T","rs2228603",0,2228603,"missense_variant",0,"NR",{"v":1E-35,"d":"1.00E-35"},35,{"$nulls":3},"NR [2501549] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":1E-35,"d":"1.00E-35"},35,null,0.08121525,"[0.068-0.094] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-19",30604766,"Morris AP","2019-01-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30604766","Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.","Estimated glomerular filtration rate","134,070 European ancestry individuals, 143,658 East Asian ancestry individuals, 26,344 Hispanic or Latino ancestry individuals, 8,224 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.534,{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.675,"[0.49-0.86] ml/min/1.73m2 decrease","Affymetrix, Illumina [at least 5248638] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.054,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58727325,"rs261332","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-?","rs261332",0,261332,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-35,"d":"2.00E-35"},34.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[33,"rs72836561",17,41840849,"rs77697917","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-C","rs77697917",0,77697917,"intergenic_variant",1,"NR",{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.153,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.079,{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.1368,"[0.12-0.16] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(TG.by.NMR, whole)",0.052,"[NR] unit increase","Illumina [335603]","N"]
[16,"rs7012637",8,9173209,"rs7012637","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs7012637-A","rs7012637",0,7012637,"intron_variant",0,0.47,{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(BMI-adjusted)",0.05,"[0.042-0.058] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[23,"rs174468",11,61663691,"rs174468","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","RAB3IL1","FADS3 - RAB3IL1","ENSG00000221968","ENSG00000167994",null,4168,1082,"rs174468-A","rs174468",0,174468,"regulatory_region_variant",1,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,null,0.04,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,null,0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44289232,"rs2732631","2019-01-28",30535121,"Gao XR","2018-12-07","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30535121","Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.","Macular thickness","59,814 European ancestry individuals","8,609 European ancestry individuals","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2732631-?","rs2732631",0,2732631,"intron_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,null,0.959,"[0.8-1.12] unit decrease","Affymetrix [11100000] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":4E-35,"d":"4.00E-35"},34.397940008672,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43654468,"rs62064364","2019-01-28",30535121,"Gao XR","2018-12-07","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30535121","Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.","Macular thickness","59,814 European ancestry individuals","8,609 European ancestry individuals","17q21.31","LRRC37A4P, MAPK8IP1P2","AC091132.4 - DND1P1","ENSG00000267198","ENSG00000282614",null,13872,8769,"rs62064364-?","rs62064364",0,62064364,"intron_variant",1,"NR",{"v":4E-35,"d":"4.00E-35"},34.397940008672,null,0.978,"[0.81-1.14] unit decrease","Affymetrix [11100000] (imputed)","N"]
[6,"rs1728918",2,27635463,"rs1728918","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":5e-35,"d":"5.00E-35"},34.3010299956639,{"$nulls":3},"Affymetrix [NR]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.087,{"v":5e-35,"d":"5.00E-35"},34.3010299956639,"(EA)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65138910,"rs7910927","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7910927-T","rs7910927",0,7910927,"intron_variant",0,0.51,{"v":6e-35,"d":"6.00E-35"},34.2218487496163,"(Men + Women)",0.048,"[0.040-0.056] umol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":7e-35,"d":"7.00E-35"},34.1549019599857,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs149580368","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs149580368-C","rs149580368",1,112259268,"intergenic_variant",1,0.973,{"v":8e-35,"d":"8.00E-35"},34.096910013008,"(EA)",0.16,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-34,"d":"1.00E-34"},34,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.0752,{"v":1e-34,"d":"1.00E-34"},34,"(Trans-ethnic initial)",0.0842,"[0.072-0.097] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-34,"d":"1.00E-34"},34,"(Uncharacterized protein C14orf93, C14orf93.6439.59.3)",0.56,"[0.46-0.66] unit decrease","Affymetrix [10572788] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.67,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,0.076,"[0.064-0.088] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.1,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,0.23,"[0.17-0.29] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.38,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,1.462,"[1.23-1.69] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,0.053,"[NR] unit decrease","NR [NR] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-34,"d":"2.00E-34"},33.698970004336,"(HBQ1)",0.60210574,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.674,{"v":3E-34,"d":"3.00E-34"},33.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.68,{"v":6E-34,"d":"6.00E-34"},33.2218487496163,null,0.077,"[0.065-0.089] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":7e-34,"d":"7.00E-34"},33.1549019599857,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-C","rs2144300",0,2144300,"intron_variant",0,"NR",{"v":7e-34,"d":"7.00E-34"},33.1549019599857,null,0.043,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity or levels","24,075 European ancestry individuals, 3,420 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.42,{"v":8e-34,"d":"8.00E-34"},33.096910013008,null,0.024,"NR unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2008-09-15",18262040,"Sandhu MS","2008-02-09","Lancet","www.ncbi.nlm.nih.gov/pubmed/18262040","LDL-cholesterol concentrations: a genome-wide association study.","LDL cholesterol","11,685 European ancestry individuals","Up to 4,979 European ancestry individuals","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.19,{"v":1e-33,"d":"1.00E-33"},33,null,0.16,"[0.14-0.18] mmol/L decrease","Affymetrix, Illumina [up to 461986]","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":1e-33,"d":"1.00E-33"},33,"(EA)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs28690720",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,"NR",{"v":1e-33,"d":"1.00E-33"},33,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.293,{"v":1e-33,"d":"1.00E-33"},33,"(Trans-ethnic initial)",0.0547,"[0.047-0.063] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":2e-33,"d":"2.00E-33"},32.698970004336,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,0.096,{"v":2e-33,"d":"2.00E-33"},32.698970004336,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131652529,"rs11950562","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean platelet volume","164,454 European ancestry individuals","NA","5q31.1","AC034220.3, SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs11950562-C","rs11950562",0,11950562,"intron_variant",0,0.4766,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,null,0.04343237,"[0.036-0.051] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[19,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":4e-33,"d":"4.00E-33"},32.397940008672,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41840849,"rs77697917","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.31","NR","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-C","rs77697917",0,77697917,"intergenic_variant",1,0.972,{"v":4e-33,"d":"4.00E-33"},32.397940008672,"(EA)",0.153,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":5e-33,"d":"5.00E-33"},32.3010299956639,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.77,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,null,5.48,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,"(EA)",0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43871982,"rs56319902","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","17q21.31",null,"CRHR1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456",null,null,"rs56319902-T","rs56319902",0,56319902,"intron_variant",0,0.2155,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,null,0.0206,"[0.017-0.024] unit decrease","Affymetrix, Illumina [10000000] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-G","rs9989419",0,9989419,"regulatory_region_variant",1,0.6,{"v":1e-32,"d":"1.00E-32"},32,null,0.04,"[0.03-0.05] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,"NR",{"v":1e-32,"d":"1.00E-32"},32,null,0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.21,{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,0.14,"[0.12-0.16] unit increase","Affymetrix [389878]","N"]
[31,"rs3764261",16,56987369,"rs56156922","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","16q13","HERPUD1, CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-?","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,0.05698,"[0.048-0.066] unit increase novel","Illumina [6108953] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.181,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(Trans-ethnic initial)",0.0555,"[0.046-0.065] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","19p13.11","SF4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":2e-32,"d":"2.00E-32"},31.698970004336,{"$nulls":3},"NR [25015711] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,null,0.049,"[NR] unit decrease","NR [NR] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,"(EA)",0.056,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.934,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,"(EA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62965621,"rs35529421","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs35529421-?","rs35529421",0,35529421,"intron_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,null,0.07475,"[0.062-0.087] unit decrease novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,"(TG.assay, fasting)",0.075,"[NR] unit increase","Illumina [335603]","N"]
[34,"rs16940904",17,43705601,"rs365825","2017-05-11",27182965,"Pickrell JK","2016-05-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27182965","Detection and interpretation of shared genetic influences on 42 human traits.","Parkinson's disease","9,619 European ancestry cases, 324,522 European ancestry controls","NA","17q21.31","CRHR1, LRRC37A3","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs365825-?","rs365825",0,365825,"intron_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,null,1.2722646,"[1.22-1.33]","Illumina [12438219] (imputed)","N"]
[4,"rs11122450",1,230307222,"rs4846923","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846923-T","rs4846923",0,4846923,"intron_variant",0,"NR",{"v":5e-32,"d":"5.00E-32"},31.3010299956639,null,0.044,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15132108,"rs2740","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","16p13.11","PDXDC1","PDXDC1, NTAN1",null,null,"ENSG00000179889, ENSG00000157045",null,null,"rs2740-A","rs2740",0,2740,"3_prime_UTR_variant",0,0.71,{"v":5e-32,"d":"5.00E-32"},31.3010299956639,"(linoleate (18:2n6)/dihomo-linolenate (20:3n3 or n6))",0.022,"[0.018-0.026] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[4,"rs11122450",1,230307222,"rs4846923","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846923-T","rs4846923",0,4846923,"intron_variant",0,0.291,{"v":6e-32,"d":"6.00E-32"},31.2218487496163,"(EA)",0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.39,{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,8.59,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[34,"rs16940904",17,44096553,"rs62062288","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.211505,{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,11.77,"z score increase","NR [10847151] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,"(EA)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43776741,"rs76761706","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs76761706-T","rs76761706",0,76761706,"intron_variant",0,0.215553,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,null,11.76,"z score decrease","NR [10847151] (imputed)","N"]
[17,"rs117026536",8,19848080,"rs17410962","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,23310,88545,"rs17410962-A","rs17410962",0,17410962,"intergenic_variant",1,0.1366,{"v":8e-32,"d":"8.00E-32"},31.096910013008,null,3.9662154,"[3.3-4.63] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[36,"rs2278426",19,11350488,"rs2278426","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","19p13.2","NR","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,"NR",{"v":8e-32,"d":"8.00E-32"},31.096910013008,null,0.05178,"[0.043-0.06] unit decrease novel","Illumina [6108953] (imputed)","N"]
[2,"rs638714",1,63094207,"rs11485618","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11485618-A","rs11485618",0,11485618,"3_prime_UTR_variant",0,0.691,{"v":1e-31,"d":"1.00E-31"},31,"(Trans-ethnic initial)",0.05,"[0.042-0.058] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[6,"rs1728918",2,27635463,"rs1728918","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"Affymetrix [NR]","N"]
[16,"rs9987289",8,9185146,"rs2126259","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"NR [2501549] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":1e-31,"d":"1.00E-31"},31,"(EA)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43810896,"rs77804065","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,null,11.693,"z score increase","Affymetrix [10847151] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.931,{"v":2e-31,"d":"2.00E-31"},30.698970004336,"(Asian initial, BMI unadjusted)",0.187,"[0.16-0.22] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.45,{"v":2e-31,"d":"2.00E-31"},30.698970004336,null,0.12,"[0.08-0.16] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":2e-31,"d":"2.00E-31"},30.698970004336,"(LDL-C.assay, whole)",6.532,"[NR] unit decrease","Illumina [335603]","N"]
[4,"rs11122450",1,230295691,"rs4846914","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,null,0.041,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(APOB.assay, whole)",4.093,"[NR] unit decrease","Illumina [335603]","N"]
[31,"rs9989419",16,56985139,"rs9989419","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-G","rs9989419",0,9989419,"regulatory_region_variant",1,0.65,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,null,1.72,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.952,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(Hispanic)",0.411,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":4e-31,"d":"4.00E-31"},30.397940008672,"(EA)",0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,{"v":4e-31,"d":"4.00E-31"},30.397940008672,null,0.05,"[NR] unit increase","NR [NR] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-31,"d":"4.00E-31"},30.397940008672,"(Carboxypeptidase A2, CPA2.9276.7.3)",0.3,"[0.24-0.36] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-29",30224653,"Evangelou E","2018-09-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30224653","Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.","Pulse pressure","757,601 European ancestry individuals","249,262 European ancestry individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412--T","rs7412",0,7412,"missense_variant",0,0.0817,{"v":5e-31,"d":"5.00E-31"},30.3010299956639,null,0.3753,"[0.31-0.44] unit decrease","Affymetrix, Illumina [~ 7100000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":5e-31,"d":"5.00E-31"},30.3010299956639,"(EA)",0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,0.41,{"v":7e-31,"d":"7.00E-31"},30.1549019599857,null,0.04,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-A","rs4846914",0,4846914,"intron_variant",0,0.584,{"v":8e-31,"d":"8.00E-31"},30.096910013008,"(Trans-ethnic initial)",0.0401,"[0.033-0.047] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[24,"rs648336",11,68732026,"rs7940105","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hair color","approximately 452,000 European ancestry individuals","NA","11q13.3",null,"AP000808.2 - MRGPRD","ENSG00000255741","ENSG00000172938",null,21705,15464,"rs7940105-?","rs7940105",0,7940105,"intergenic_variant",1,"NR",{"v":9e-31,"d":"9.00E-31"},30.0457574905606,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[28,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,"NR",{"v":9e-31,"d":"9.00E-31"},30.0457574905606,null,0.138,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43555253,"rs56192752","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","17q21.31",null,"PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs56192752-A","rs56192752",0,56192752,"3_prime_UTR_variant",0,0.8218,{"v":9e-31,"d":"9.00E-31"},30.0457574905606,"(conditional-joint)",0.0218,"[0.018-0.026] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":1e-30,"d":"1.00E-30"},30,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44207932,"rs79301522","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs79301522-A","rs79301522",0,79301522,"intron_variant",0,0.217029,{"v":1e-30,"d":"1.00E-30"},30,null,11.51,"z score decrease","NR [10847151] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2011-01-14",21087763,"Carrasquillo MM","2010-12-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/21087763","Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.","Progranulin levels","518 European ancestry controls","459 European ancestry controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.21,{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.18,"[0.16-0.20] ng/ml decrease","Illumina [313504]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.024,"[0.02-0.028] unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[17,"rs117026536",8,19845376,"rs7841189","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,20606,91249,"rs7841189-T","rs7841189",0,7841189,"TF_binding_site_variant",1,0.1,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(BMI unadjusted)",0.172,"[0.14-0.2] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.095,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.12,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(TC)",0.09,"[0.070-0.110] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[19,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":3e-30,"d":"3.00E-30"},29.5228787452803,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-A","rs1532624",0,1532624,"intron_variant",0,0.49,{"v":3e-30,"d":"3.00E-30"},29.5228787452803,"(Indian)",2.53,"[2.1-2.96] unit increase","Illumina [551825]","N"]
[34,"rs7225002",17,44189067,"rs7225002","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","17q21.31",null,"KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs7225002-?","rs7225002",0,7225002,"intron_variant",0,"NR",{"v":3e-30,"d":"3.00E-30"},29.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs261291",15,58674308,"rs2043082","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043082-?","rs2043082",0,2043082,"intron_variant",0,"NR",{"v":4e-30,"d":"4.00E-30"},29.397940008672,null,0.04481,"[0.037-0.053] unit increase novel","Illumina [6108953] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,0.053,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":6e-30,"d":"6.00E-30"},29.2218487496163,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,"NR",{"v":6e-30,"d":"6.00E-30"},29.2218487496163,null,0.057,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.52,{"v":7e-30,"d":"7.00E-30"},29.1549019599857,"(Asian initial, BMI unadjusted)",0.1,"[0.082-0.118] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.416,{"v":8e-30,"d":"8.00E-30"},29.096910013008,null,0.063,"[0.051-0.075] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":9e-30,"d":"9.00E-30"},29.0457574905606,"(APOB)",0.57334346,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.16,{"v":1e-29,"d":"1.00E-29"},29,"(BMI unadjusted)",0.232,"[0.19-0.27] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[34,"rs16940904",17,44096553,"rs62062288","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Risk-taking tendency (4-domain principal component model)","315,894 European ancestry individuals","NA","17q21.31","KANSL1","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.2207,{"v":1e-29,"d":"1.00E-29"},29,null,0.035170935,"[0.029-0.041] unit decrease","Affymetrix [~ 11515000] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230304914,"rs10864728","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs10864728-A","rs10864728",0,10864728,"intron_variant",0,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.04,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230305312,"rs1321257","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs1321257-G","rs1321257",0,1321257,"intron_variant",0,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.04,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,7.83,"[6.22-9.44] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","1p13.3","PSRC1, CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.24,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.16,"[0.14-0.18] unit decrease","Affymetrix [389878]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,"(TG.by.NMR, fasting)",0.056,"[NR] unit increase","Illumina [335603]","N"]
[18,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.46,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,1.84,"[1.51-2.17] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.04,"[NR] unit increase","NR [NR] (imputed)","N"]
[34,"rs16940904",17,44018399,"rs62061733","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62061733-?","rs62061733",0,62061733,"intron_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs7412",19,45416831,"rs390082","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs390082-?","rs390082",0,390082,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.09747,"[0.08-0.114] unit increase novel","Illumina [6108953] (imputed)","N"]
[34,"rs16940904",17,44363929,"rs2696500","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2696500-T","rs2696500",0,2696500,"intron_variant",0,0.214048,{"v":4e-29,"d":"4.00E-29"},28.397940008672,null,11.21,"z score increase","NR [10847151] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.798,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(Hispanic)",0.21,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.2,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,null,0.16,"[0.12-0.20] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.21,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(HDL)",0.254,"[0.21-0.3] unit increase","Illumina [561583]","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":6e-29,"d":"6.00E-29"},28.2218487496163,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-C","rs2144300",0,2144300,"intron_variant",0,0.397,{"v":7e-29,"d":"7.00E-29"},28.1549019599857,"(EA)",0.043,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","HDL cholesterol","4,763 Northern Finnish founder individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.28,{"v":7e-29,"d":"7.00E-29"},28.1549019599857,null,0.09,"[0.08-0.11] mmol/l increase","Illumina [329091]","N"]
[34,"rs16940904",17,43844560,"rs55657917","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","HOXB2","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs55657917-T","rs55657917",0,55657917,"intron_variant",0,0.213403,{"v":7e-29,"d":"7.00E-29"},28.1549019599857,null,11.16,"z score decrease","NR [10847151] (imputed)","N"]
[4,"rs11122450",1,230304914,"rs10864728","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs10864728-A","rs10864728",0,10864728,"intron_variant",0,0.387,{"v":8e-29,"d":"8.00E-29"},28.096910013008,"(EA)",0.043,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57006378,"rs11076175","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs11076175-?","rs11076175",0,11076175,"intron_variant",0,"NR",{"v":8e-29,"d":"8.00E-29"},28.096910013008,"(Total cholesterol in HDL, conditioned)",0.1511545,"[0.12-0.18] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[34,"rs16940904",17,44066172,"rs112385572","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","CRHR1, KANSL1, MAPT, PLEKHM1, SPPL2C, STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs112385572-G","rs112385572",0,112385572,"intron_variant",0,"NR",{"v":8e-29,"d":"8.00E-29"},28.096910013008,null,0.0768246,"NR unit decrease","NR [NR] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.11","CILP2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.92,{"v":8e-29,"d":"8.00E-29"},28.096910013008,null,0.122,"[0.1-0.14] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","LDL cholesterol","7,565 African American individuals","3,789 African American and Afro-Caribbean individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.25,{"v":9e-29,"d":"9.00E-29"},28.0457574905606,null,0.1815,"[0.15-0.21] unit decrease","Affymetrix [~ 2740000] (imputed)","N"]
[4,"rs11122450",1,230305312,"rs1321257","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs1321257-G","rs1321257",0,1321257,"intron_variant",0,0.387,{"v":9e-29,"d":"9.00E-29"},28.0457574905606,"(EA)",0.043,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2015-06-08",25350695,"Postmus I","2014-10-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25350695","Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.","Response to statins (LDL cholesterol change)","18,596 European ancestry individuals","23,279 European ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.157,{"v":9e-29,"d":"9.00E-29"},28.0457574905606,null,0.051,"[0.041-0.061] unit decrease","Affymetrix, Illumina, Perlegen [at least 2500000] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.797,{"v":1e-28,"d":"1.00E-28"},28,"(Hispanic)",0.208,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","LDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-C","rs660240",0,660240,"3_prime_UTR_variant",0,0.793,{"v":1e-28,"d":"1.00E-28"},28,"(Hispanic)",0.179,"[0.15-0.21] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-28,"d":"1.00E-28"},28,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43714850,"rs2942168","2015-04-20",21292315,"Nalls MA","2011-02-01","Lancet","www.ncbi.nlm.nih.gov/pubmed/21292315","Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.","Parkinson's disease","5,333 European ancestry cases, 12,019 European ancestry controls","7,053 cases, 9,007 controls","17q21.31","MAPT","LINC02210-CRHR1, LINC02210-CRHR1, LINC02210",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000204650",null,null,"rs2942168-G","rs2942168",0,2942168,"non_coding_transcript_exon_variant",0,0.78,{"v":1e-28,"d":"1.00E-28"},28,null,1.27,"[1.23-1.31]","Illumina [7689524] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-?","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.1122,"[0.092-0.132] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2e-28,"d":"2.00E-28"},27.698970004336,"(EA)",0.025,"NR unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.19,"[0.15-0.23] unit decrease","Affymetrix [389878]","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43811072,"rs17563683","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","17q21.31","CRHR1, RP11-105N13.4, RP11-293E1.1","AC217774.2, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000265964, ENSG00000263715, ENSG00000282456",null,null,"rs17563683-G","rs17563683",0,17563683,"intron_variant",0,0.2333,{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.04515636,"[0.037-0.053] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,44018399,"rs62061733","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62061733-A","rs62061733",0,62061733,"intron_variant",0,0.22111,{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,11.07,"z score decrease","NR [10847151] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2e-28,"d":"2.00E-28"},27.698970004336,"(Pregnancy-specific beta-1-glycoprotein 5, PSG5.9314.9.3)",0.5,"[0.4-0.6] unit decrease","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3E-28,"d":"3.00E-28"},27.5228787452803,"(VLDL.large, whole)",0.342,"[NR] unit increase","Illumina [335603]","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44192957,"rs17661015","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs17661015-T","rs17661015",0,17661015,"intron_variant",0,0.215131,{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,11.02,"z score decrease","NR [10847151] (imputed)","N"]
[34,"rs16940904",17,44797919,"rs199456","2019-01-28",30535121,"Gao XR","2018-12-07","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30535121","Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.","Macular thickness","59,814 European ancestry individuals","8,609 European ancestry individuals","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199456-?","rs199456",0,199456,"intron_variant",0,"NR",{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,0.86,"[0.7-1.02] unit decrease","Affymetrix [11100000] (imputed)","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.677,{"v":4e-28,"d":"4.00E-28"},27.397940008672,"(East Asian)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43896032,"rs62057107","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Highest math class taken (MTAG)","811,539 European ancestry individuals","NA","17q21.31","Intergenic","MAPT-AS1, MAPT-AS1, MAPT-AS1, CRHR1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000278232, ENSG00000263715, ENSG00000282456",null,null,"rs62057107-T","rs62057107",0,62057107,"intron_variant",0,0.2219,{"v":4e-28,"d":"4.00E-28"},27.397940008672,"(MTAG)",{"v":0.022,"d":"2.20E-02"},"[0.018-0.026] unit decrease","Affymetrix, Illumina [7100000] (imputed)","N"]
[17,"rs117026536",8,19848080,"rs17410962","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,23310,88545,"rs17410962-A","rs17410962",0,17410962,"intergenic_variant",1,0.1366,{"v":5e-28,"d":"5.00E-28"},27.3010299956639,null,8.334999,"[6.85-9.82] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q15.3","MAP1A","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-T","rs55707100",0,55707100,"missense_variant",0,0.0279,{"v":5e-28,"d":"5.00E-28"},27.3010299956639,null,0.0939,"[0.077-0.111] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs11407273",11,61639573,"rs174448","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS3","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,"NR",{"v":7e-28,"d":"7.00E-28"},27.1549019599857,null,0.05,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":7e-28,"d":"7.00E-28"},27.1549019599857,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":8e-28,"d":"8.00E-28"},27.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,44324572,"rs555203107","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","17q21.31","NR","MAPK8IP1P1 - AC005829.2","ENSG00000281283","ENSG00000262539",null,2162,12345,"rs555203107-G","rs555203107",1,62073112,"regulatory_region_variant",1,"NR",{"v":8e-28,"d":"8.00E-28"},27.096910013008,null,0.0516895,"[0.042-0.061] unit increase","Affymetrix [16832071] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,0.397,{"v":9e-28,"d":"9.00E-28"},27.0457574905606,"(EA)",0.042,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":1E-27,"d":"1.00E-27"},27,null,0.0422174,"[0.034-0.05] unit increase","Affymetrix [16832071] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2008-06-22",18454146,"Chambers JC","2008-05-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18454146","Common genetic variation near MC4R is associated with waist circumference and insulin resistance.","Waist circumference and related phenotypes","2,684 Indian Asian ancestry male individuals","7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-?","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":1E-27,"d":"1.00E-27"},27,"(HDL cholesterol)",null,null,"Illumina [308067]","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.821,{"v":1E-27,"d":"1.00E-27"},27,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43924219,"rs12373124","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","NR","SPPL2C, SPPL2C, SPPL2C, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000277106, ENSG00000185294, ENSG00000278194, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs12373124-C","rs12373124",0,12373124,"synonymous_variant",0,"NR",{"v":1E-27,"d":"1.00E-27"},27,null,0.08,"NR unit decrease","NR [NR] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(LDL.total, whole)",0.042,"[NR] unit decrease","Illumina [335603]","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,0.056,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58730498,"rs588136","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","15q21.3","LIPC","LIPC-AS1, ALDH1A2, LIPC",null,null,"ENSG00000259293, ENSG00000128918, ENSG00000166035",null,null,"rs588136-T","rs588136",0,588136,"intron_variant",0,0.794,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Trans-ethnic initial)",0.0495,"[0.041-0.058] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.874,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Hispanic)",0.201,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44098967,"rs17652520","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Neuroticism","approximately 372,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17652520-?","rs17652520",0,17652520,"intron_variant",0,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,44787312,"rs1378358","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs1378358-T","rs1378358",0,1378358,"intron_variant",0,0.206287,{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,10.86,"z score increase","NR [10847151] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease","10,874 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06071,{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,0.04,"[-1.5672-1.6472] unit decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(FAM159B)",0.5431671,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Tumor protein p53-inducible protein 11, TP53I11.13022.20.3)",0.5,"[0.4-0.6] unit decrease","Affymetrix [10572788] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Melanoma-associated antigen 3, MAGEA3.12576.21.3)",0.28,"[0.22-0.34] unit increase","Affymetrix [10572788] (imputed)","N"]
[19,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.294,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(Trans-ethnic initial)",0.0395,"[0.032-0.047] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.927,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.925,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(EA)",0.095,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.782,{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,1.11,"[1.09-1.14]","Affymetrix [9149595] (imputed)","N"]
[29,"rs28690720",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.861,{"v":4e-27,"d":"4.00E-27"},26.397940008672,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44787313,"rs538628","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","ARL17A, LRRC37A2, NSF, WNT3","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs538628-C","rs538628",0,538628,"intron_variant",0,"NR",{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,0.0800835,"NR unit decrease","NR [NR] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-27,"d":"5.00E-27"},26.3010299956639,null,0.08159,"[0.067-0.096] unit increase novel","Illumina [6108953] (imputed)","N"]
[17,"rs117026536",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.9,{"v":6e-27,"d":"6.00E-27"},26.2218487496163,"(BMI unadjusted)",0.175,"[0.14-0.21] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.39,{"v":6e-27,"d":"6.00E-27"},26.2218487496163,"(Indian)",2.4,"[1.97-2.83] unit decrease","Illumina [551825]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":7e-27,"d":"7.00E-27"},26.1549019599857,null,1.91,"[1.54-2.28] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[28,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,0.971,{"v":7e-27,"d":"7.00E-27"},26.1549019599857,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230295307,"rs17315646","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs17315646-G","rs17315646",0,17315646,"intron_variant",0,0.592,{"v":8e-27,"d":"8.00E-27"},26.096910013008,"(Dual specificity mitogen-activated protein kinase kinase 4, MAP2K4.5242.37.3)",0.27,"[0.23-0.31] unit decrease","Affymetrix [10572788] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.792,{"v":9e-27,"d":"9.00E-27"},26.0457574905606,"(Hispanic)",0.172,"[0.14-0.2] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2010-01-13",20031538,"Heid IM","2008-10-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031538","Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.","HDL cholesterol","Up to 4,274 European ancestry individuals","Up to 15,873 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.38,{"v":9e-27,"d":"9.00E-27"},26.0457574905606,null,2.66,"[NR] mg/dl decrease","Affymetrix [up to 2557253] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-A","rs660240",0,660240,"3_prime_UTR_variant",0,0.21,{"v":1E-26,"d":"1.00E-26"},26,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.368,{"v":1E-26,"d":"1.00E-26"},26,"(Hispanic)",0.15,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs2603187",4,69338311,"rs969114","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4q13.2","TMPRSS11E","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs969114-A","rs969114",0,969114,"intron_variant",0,0.5722,{"v":1E-26,"d":"1.00E-26"},26,null,0.029,"[0.024-0.034] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-T","rs10808546",0,10808546,"intron_variant",0,0.446,{"v":1E-26,"d":"1.00E-26"},26,"(Trans-ethnic initial)",0.0409,"[0.034-0.048] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[28,"rs139974673",15,44028047,"rs147233090","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","15q15.3","NR","CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs147233090-T","rs147233090",0,147233090,"intron_variant",0,0.0267,{"v":1E-26,"d":"1.00E-26"},26,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[34,"rs16940904",17,44065740,"rs919462","2018-01-12",29146897,"Pirastu N","2017-11-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29146897","GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.","Male-pattern baldness","25,662 British ancestry cases, 17,928 British ancestry controls","13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls","17q21.31","WNT3, MAPT, PLEKHM1","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs919462-C","rs919462",0,919462,"intron_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,null,0.168393,"[0.14-0.2] unit decrease","Affymetrix [27512692] (imputed)","N"]
[34,"rs16940904",17,44318184,"rs2696668","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","KANSL1 - MAPK8IP1P1","ENSG00000278458","ENSG00000281283",null,15429,2788,"rs2696668-A","rs2696668",0,2696668,"intergenic_variant",1,0.215905,{"v":1E-26,"d":"1.00E-26"},26,null,10.68,"z score decrease","NR [10847151] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.03923603,"[0.032-0.046] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[17,"rs117026536",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.9,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(Asian initial, BMI unadjusted)",0.175,"[0.14-0.21] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","15q15.3","MAP1A","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-T","rs55707100",0,55707100,"missense_variant",0,0.0261,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.1223192,"[0.1-0.145] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.822,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44812188,"rs199447","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199447-T","rs199447",0,199447,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,10.659,"z score increase","Affymetrix [10847151] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.26,"[0.18-0.34] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(Surfeit locus protein 1, SURF1.8009.121.3)",0.49,"[0.39-0.59] unit decrease","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Total cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.063,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,13.1251,"[10.72-15.53] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.895,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,"(Asian initial, BMI unadjusted)",0.15,"[0.12-0.18] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-?","rs261291",0,261291,"intron_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.04531,"[0.037-0.054] unit increase novel","Illumina [6108953] (imputed)","N"]
[34,"rs16940904",17,43811072,"rs17563683","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","17q21.31","CRHR1, RP11-105N13.4, RP11-293E1.1","AC217774.2, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000265964, ENSG00000263715, ENSG00000282456",null,null,"rs17563683-G","rs17563683",0,17563683,"intron_variant",0,0.2333,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.04344178,"[0.035-0.051] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,43950976,"rs10491140","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","17q21.31",null,"MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs10491140-?","rs10491140",0,10491140,"intron_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.0257143,"[0.021-0.031] unit increase","Affymetrix [20259828] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,"(Nuclear receptor-binding protein, NRBP1.12616.45.3)",0.49,"[0.39-0.59] unit decrease","Affymetrix [10572788] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":4e-26,"d":"4.00E-26"},25.397940008672,null,0.066,"[0.054-0.078] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.763,{"v":4e-26,"d":"4.00E-26"},25.397940008672,"(East Asian)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.9,{"v":4e-26,"d":"4.00E-26"},25.397940008672,null,9.17,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[27,"rs78689694",11,126238633,"rs74612335","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum alkaline phosphatase levels","105,030 Japanese ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs74612335-?","rs74612335",0,74612335,"intron_variant",0,"NR",{"v":6e-26,"d":"6.00E-26"},25.2218487496163,null,0.04903,"[0.04-0.058] unit decrease novel","Illumina [6108953] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.931,{"v":7e-26,"d":"7.00E-26"},25.1549019599857,"(Asian initial, BMI unadjusted)",0.168,"[0.14-0.2] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (small molecules and protein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.64,{"v":7e-26,"d":"7.00E-26"},25.1549019599857,"(Alanine)",0.1,"[0.08-0.12] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":7e-26,"d":"7.00E-26"},25.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[17,"rs117026536",8,19819328,"rs325","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs325-T","rs325",0,325,"intron_variant",0,0.89,{"v":8e-26,"d":"8.00E-26"},25.096910013008,null,0.05,"[0.04-0.06] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[34,"rs16940904",17,43810896,"rs77804065","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","ARHGAP27, CRHR1, KANSL1, MAPT, PLEKHM1, SPPL2C, STH","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,0.21716,{"v":8e-26,"d":"8.00E-26"},25.096910013008,null,10.503,"z score increase","Illumina [18485882] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.209,{"v":9e-26,"d":"9.00E-26"},25.0457574905606,"(Hispanic)",0.194,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43933941,"rs139097404","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q15.3","CATSPER2","CATSPER2",null,null,"ENSG00000166762",null,null,"rs139097404-T","rs139097404",0,139097404,"intron_variant",0,0.9746,{"v":9e-26,"d":"9.00E-26"},25.0457574905606,null,0.0988,"[0.08-0.117] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[4,"rs11122450",1,230296153,"rs10864726","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs10864726-T","rs10864726",0,10864726,"intron_variant",0,0.5956,{"v":1E-25,"d":"1.00E-25"},25,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[5,"rs562338",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":1E-25,"d":"1.00E-25"},25,"(APOB.assay, fasting)",4.355,"[NR] unit decrease","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[10,"rs272863",5,131661156,"rs273913","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs273913-T","rs273913",0,273913,"intron_variant",0,0.38,{"v":1E-25,"d":"1.00E-25"},25,"(3-dehydrocarnitine)",0.026,"[0.02-0.032] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.5421,{"v":1E-25,"d":"1.00E-25"},25,null,0.0666,"[0.054-0.079] unit increase","NR [8041861] (imputed)","N"]
[21,"rs7924036",10,65138910,"rs7910927","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7910927-T","rs7910927",0,7910927,"intron_variant",0,0.51,{"v":1E-25,"d":"1.00E-25"},25,"(Men)",0.05,"[0.041-0.059] umol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs490098",15,58694020,"rs16940212","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940212-T","rs16940212",0,16940212,"intron_variant",0,0.3,{"v":1E-25,"d":"1.00E-25"},25,"(BMI unadjusted)",0.102,"[0.082-0.122] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[34,"rs16940904",17,43688317,"rs28768976","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,2033,9377,"rs28768976-A","rs28768976",0,28768976,"intergenic_variant",1,0.77211,{"v":1E-25,"d":"1.00E-25"},25,null,10.453,"z score decrease","Illumina [18485882] (imputed)","N"]
[34,"rs16940904",17,44098967,"rs17652520","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17652520-A","rs17652520",0,17652520,"intron_variant",0,0.2216,{"v":1E-25,"d":"1.00E-25"},25,null,10.472,"z score increase","Illumina [18485882] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,"(LDL-C.assay, fasting)",6.892,"[NR] unit decrease","Illumina [335603]","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.016,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.282,"[0.23-0.33] unit decrease","Affymetrix [7947838] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0163,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.2821,"[0.23-0.34] unit decrease","NR [8041861] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.605,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.03860428,"[0.031-0.046] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.09,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.065,"[0.053-0.077] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.11,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(Triglycerides in small VLDL)",0.18,"[0.14-0.22] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.04,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-T","rs3764261",0,3764261,"regulatory_region_variant",1,0.16,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(HDL)",0.062,"[0.046-0.078] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43953719,"rs2214258","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs2214258-C","rs2214258",0,2214258,"intron_variant",0,0.21533,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,10.415,"z score increase","Illumina [18485882] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","19p13.11","CILP2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.92,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.116,"[0.094-0.138] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(TBCA)",0.51885974,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.209,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,"(Hispanic)",0.192,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-?","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[15,"rs33951980",7,72971231,"rs13233571","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","7q11.23","BCL7B","BCL7B",null,null,"ENSG00000106635",null,null,"rs13233571-C","rs13233571",0,13233571,"intron_variant",0,0.12,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.057,"[0.047-0.067] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[15,"rs62466318",7,73037366,"rs55747707","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","7q11.23",null,"MLXIPL",null,null,"ENSG00000009950",null,null,"rs55747707-?","rs55747707",0,55747707,"intron_variant",0,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.0422,"[0.034-0.05] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58678720,"rs261290","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","15q21.3","ALDH1A2","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261290-C","rs261290",0,261290,"intron_variant",0,0.3442,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.121454455,"[0.099-0.144] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[31,"rs1864163",16,56997233,"rs1864163","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1864163-?","rs1864163",0,1864163,"intron_variant",0,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,"(LDL.large, whole)",27.87,"[NR] unit decrease","Illumina [335603]","N"]
[34,"rs7221167",17,43933307,"rs7221167","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","17q21.31",null,"MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs7221167-?","rs7221167",0,7221167,"intron_variant",0,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,44221836,"rs2696589","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2696589-T","rs2696589",0,2696589,"intron_variant",0,0.19528,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,10.371,"z score increase","Illumina [18485882] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.91,{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.044,"[0.036-0.052] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs11407273",11,61639573,"rs174448","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS3","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.01,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-25,"d":"4.00E-25"},24.397940008672,"(Cadherin-related family member 5, CDHR5.9962.1.3)",0.47,"[0.37-0.57] unit decrease","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Serum total cholesterol levels","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.399,"unit decrease","Illumina [15144991] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.63,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,null,1.06,"[1.05-1.08]","Affymetrix, Illumina [247470]","N"]
[23,"rs7943992",11,61272565,"rs7125196","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","11q12.2","LOC105369329, MIR4488","AP003108.1 - MIR4488","ENSG00000255931","ENSG00000266006",null,5017,3503,"rs7125196-T","rs7125196",0,7125196,"intergenic_variant",1,0.77,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,"(Asian, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[36,"rs151113958",19,11193949,"rs10412048","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19p13.2","intergenic","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,3847,6089,"rs10412048-G","rs10412048",0,10412048,"intergenic_variant",1,0.1086,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,null,0.18101913,"[0.15-0.22] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":5e-25,"d":"5.00E-25"},24.3010299956639,"(APOB.assay, whole)",4.516,"[NR] unit decrease","Illumina [335603]","N"]
[38,"rs7412",19,45415640,"rs445925","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-25,"d":"5.00E-25"},24.3010299956639,null,0.0631036,"[0.051-0.076] unit increase","Affymetrix [16832071] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.09,{"v":6e-25,"d":"6.00E-25"},24.2218487496163,null,1.21,"[0.96-1.46] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":7e-25,"d":"7.00E-25"},24.1549019599857,null,0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43964567,"rs62055546","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","17q21.31","MAPT","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs62055546-A","rs62055546",0,62055546,"intron_variant",0,0.7779,{"v":8e-25,"d":"8.00E-25"},24.096910013008,null,0.027622232,"[0.022-0.033] unit increase","Affymetrix [11514936] (imputed)","N"]
[11,"rs59136961",6,34603646,"rs2492863","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p21.31","C6orf106, SNRPC, UHRF1BP1","C6orf106",null,null,"ENSG00000196821",null,null,"rs2492863-A","rs2492863",0,2492863,"intron_variant",0,0.139616,{"v":1e-24,"d":"1.00E-24"},24,"(females)",0.04558,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[28,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,"NR",{"v":1e-24,"d":"1.00E-24"},24,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs490098",15,58694020,"rs16940212","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","15q21.3","intergenic","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940212-T","rs16940212",0,16940212,"intron_variant",0,0.34,{"v":1e-24,"d":"1.00E-24"},24,null,0.0222,"[0.018-0.027] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","16q13","NLRC5, SLC12A3, HERPUD1, CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-A","rs1532624",0,1532624,"intron_variant",0,0.43,{"v":1e-24,"d":"1.00E-24"},24,null,0.23,"[0.19-0.27] unit increase","Illumina [1361436] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":1e-24,"d":"1.00E-24"},24,"(DNA/RNA-binding protein KIN17, KIN.14643.27.3)",0.47,"[0.37-0.57] unit increase","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,"(mannose)",0.04725,"[NR] unit decrease","Affymetrix [655658]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,{"$nulls":3},"NR [2501749] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-A","rs112875651",0,112875651,"intron_variant",0,0.3925,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.03782324,"[0.031-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[21,"rs201220977",10,65027610,"rs10761731","2015-05-05",22139419,"Gieger C","2011-11-30","Nature","www.ncbi.nlm.nih.gov/pubmed/22139419","New gene functions in megakaryopoiesis and platelet formation.","Platelet count","38,891 European ancestry individuals, 1,661 Val Borbera (founder/genetic isolate) individuals, 521 Carlantino (founder/genetic isolate) individuals, 1,198 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,213 South Tyrolean (founder/genetic isolate) individuals, 890 Sorbian (founder/genetic isolate) individuals, 4,292 Sardinian (founder/genetic isolate) individuals","Up to 16,949 European ancestry individuals, 854 Cliento (founder/genetic isolate) individuals, 1,035 Talana (founder/genetic isolate) individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,3.849,"[3.11-4.59] 10^9/l increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.69,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.069,"[0.055-0.083] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[34,"rs16940904",17,43573419,"rs62065453","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,5304,10688,"rs62065453-T","rs62065453",0,62065453,"intergenic_variant",1,0.21717,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,10.227,"z score increase","Illumina [18485882] (imputed)","N"]
[36,"rs151113958",19,11192193,"rs61194703","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","19p13.2",null,"SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,2091,7845,"rs61194703-?","rs61194703",0,61194703,"intergenic_variant",1,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[37,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.091,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-01-23",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Homeostasis model assessment of insulin resistance","37,037 European ancestry individuals","62,264 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.035,"[0.027-0.043] unit increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.3995,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.0318,"[0.026-0.038] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,"(DNA repair protein XRCC4, XRCC4.9886.28.3)",0.26,"[0.2-0.32] unit increase","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(VLDL.large, fasting)",0.362,"[NR] unit increase","Illumina [335603]","N"]
[6,"rs1260326",2,27741237,"rs780094","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4008,{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,1E-3,"[-0.00034-0.00234] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723939,"rs2070895","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-A","rs2070895",0,2070895,"intron_variant",0,0.43,{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,0.0374,"[0.03-0.045] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[34,"rs16940904",17,44773783,"rs199441","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199441-A","rs199441",0,199441,"intron_variant",0,0.217502,{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,10.14,"z score increase","NR [10847151] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(GGT2)",0.51045436,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Pulse pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0833,{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,0.3606,"[0.29-0.43] mmHg decrease","Affymetrix [NR] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-?","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":5e-24,"d":"5.00E-24"},23.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.798,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(Hispanic)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(EA)",0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.57,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(HDL)",0.13,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[34,"rs16940904",17,43853922,"rs56303031","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","17q21.31",null,"LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs56303031-?","rs56303031",0,56303031,"intron_variant",0,"NR",{"v":6e-24,"d":"6.00E-24"},23.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-10-17",28937693,"Clarke TK","2017-07-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28937693","Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).","Alcohol consumption in current drinkers","108,309 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-G","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":7e-24,"d":"7.00E-24"},23.1549019599857,null,0.03,"[0.024-0.036] unit decrease","Affymetrix [12489781] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.838,{"v":8e-24,"d":"8.00E-24"},23.096910013008,"(East Asian)",0.181,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-T","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,3.14,"[2.51-3.77] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,0.071,"[NR] unit decrease","NR [NR] (imputed)","N"]
[36,"rs151113958",19,11210912,"rs2228671","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs2228671-G","rs2228671",0,2228671,"stop_gained",0,0.88,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,0.16,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.797,{"v":1e-23,"d":"1.00E-23"},23,"(Hispanic)",0.187,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.199,{"v":1e-23,"d":"1.00E-23"},23,"(Hispanic)",0.19,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.478,{"v":1e-23,"d":"1.00E-23"},23,"(East Asian)",0.145,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":1e-23,"d":"1.00E-23"},23,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2017-09-12",20838585,"Smith EN","2010-09-09","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20838585","Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.","Cardiovascular risk factors","525 European ancestry individuals","2,442 Finnish ancestry individuals","16q13","CETP, HERPUD1","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":1e-23,"d":"1.00E-23"},23,"(HDL-cholesterol)",2.99,"[2.42-3.56] unit increase","Illumina [2173391] (imputed)","N"]
[34,"rs16940904",17,43569909,"rs146746174","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Cognitive performance (MTAG)","402,382 European ancestry individuals","NA","17q21.31","Intergenic","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,1794,14198,"rs146746174-T","rs146746174",1,62065449,"intergenic_variant",1,0.815,{"v":1e-23,"d":"1.00E-23"},23,"(MTAG)",0.0297,"[0.024-0.036] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[37,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.934,{"v":1e-23,"d":"1.00E-23"},23,"(EA)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs190921611",19,45490192,"rs11672748","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","CLPTM1","CLPTM1",null,null,"ENSG00000104853",null,null,"rs11672748-G","rs11672748",0,11672748,"non_coding_transcript_exon_variant",0,0.3171,{"v":1e-23,"d":"1.00E-23"},23,null,10.028075,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.78582,{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,1.12,"[1.10- 1.15]","Affymetrix, Illumina [8600000] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.223,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(Carbonic anhydrase-related protein 10, CA10.13666.222.3)",0.3,"[0.24-0.36] unit decrease","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-04-26",26974007,"Ellinghaus D","2016-03-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26974007","Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.","Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)","8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(subset analysis)",null,null,"Illumina [130052]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.07,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65010672,"rs10995477","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10995477-C","rs10995477",0,10995477,"intron_variant",0,0.4723,{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.03576595,"[0.029-0.043] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","15q15.3","MAP1A","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-T","rs55707100",0,55707100,"missense_variant",0,0.0261,{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.1142708,"[0.092-0.137] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,44351387,"rs2732708","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","AC005829.1 - ARL17B","ENSG00000261575","ENSG00000228696",null,5327,763,"rs2732708-T","rs2732708",0,2732708,"intergenic_variant",1,0.21404,{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,9.955,"z score increase","Illumina [18485882] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(KIN)",0.4950121,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.369,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,"(Hispanic)",0.14,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65134778,"rs2893919","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs2893919-A","rs2893919",0,2893919,"intron_variant",0,0.4446,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[37,"rs58542926",19,19460541,"rs73001065","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19p13.11","CILP2","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.93,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,null,0.114,"[0.09-0.138] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":4e-23,"d":"4.00E-23"},22.397940008672,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65010672,"rs10995477","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10995477-C","rs10995477",0,10995477,"intron_variant",0,0.4722,{"v":5e-23,"d":"5.00E-23"},22.3010299956639,null,0.03549842,"[0.028-0.043] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.08,{"v":5e-23,"d":"5.00E-23"},22.3010299956639,"(X-11820/cholesterol)",0.089,"[0.071-0.107] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.5398,{"v":6e-23,"d":"6.00E-23"},22.2218487496163,null,0.0546,"[0.044-0.065] unit increase","NR [8041861] (imputed)","N"]
[21,"rs7924036",10,65133822,"rs7923609","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alkaline phosphatase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","10q21.3","JMJD1C, NRBF2","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7923609-G","rs7923609",0,7923609,"intron_variant",0,0.5,{"v":6e-23,"d":"6.00E-23"},22.2218487496163,null,2.2,"[1.70-2.70] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs72789541",16,15140211,"rs4500751","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","16p13.11","PDXDC1","PDXDC1, NTAN1",null,null,"ENSG00000179889, ENSG00000157045",null,null,"rs4500751-?","rs4500751",0,4500751,"intron_variant",0,"NR",{"v":6e-23,"d":"6.00E-23"},22.2218487496163,"(levels)",0,"[0.80-2.40] % increase","Illumina [NR] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.16,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":8e-23,"d":"8.00E-23"},22.096910013008,"(men)",0.052,"[NR] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.467,{"v":8e-23,"d":"8.00E-23"},22.096910013008,"(East Asian)",0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126479362,"rs6982502","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982502-T","rs6982502",0,6982502,"intron_variant",0,0.5298,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.0498,"[0.04-0.06] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.3,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.1,"[0.06-0.14] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":9e-23,"d":"9.00E-23"},22.0457574905606,null,0.17,"[0.13-0.21] unit increase","Affymetrix [389878]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.0752,{"v":1E-22,"d":"1.00E-22"},22,"(Trans-ethnic initial)",0.0714,"[0.058-0.084] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1E-22,"d":"1.00E-22"},22,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs201220977",10,65104500,"rs7896518","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-G","rs7896518",0,7896518,"intron_variant",0,0.4277,{"v":1E-22,"d":"1.00E-22"},22,null,0.03597332,"[0.029-0.043] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65118203,"rs10822161","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum alkaline phosphatase levels","105,030 Japanese ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10822161-?","rs10822161",0,10822161,"intron_variant",0,"NR",{"v":1E-22,"d":"1.00E-22"},22,null,0.04283,"[0.034-0.051] unit increase novel","Illumina [6108953] (imputed)","N"]
[27,"rs78689694",11,126241979,"rs10893499","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs10893499-G","rs10893499",0,10893499,"intron_variant",0,"NR",{"v":1E-22,"d":"1.00E-22"},22,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":1E-22,"d":"1.00E-22"},22,"(EA)",0.048,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.17,{"v":1E-22,"d":"1.00E-22"},22,null,4.439,"[3.56-5.32] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0164,{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.2406,"[0.19-0.29] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.22,{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(activity)",0.0344,"[0.027-0.042] ng/ml decrease","Illumina [796174]","N"]
[3,"rs629301",1,109817838,"rs660240","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.22,{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(LDL)",0.17,"[0.14-0.20] mmol/l decrease","Illumina [NR] (imputed)","N"]
[5,"rs562338",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(LDL.total, whole)",0.04,"[NR] unit decrease","Illumina [335603]","N"]
[18,"rs2954021",8,126478350,"rs2980853","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8q24.13","NR","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27703,831,"rs2980853-?","rs2980853",0,2980853,"intergenic_variant",1,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[21,"rs7924036",10,64988931,"rs7916868","2016-10-05",26561523,"de Vries PS","2015-11-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/26561523","A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.","Fibrinogen levels","120,246 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7916868-A","rs7916868",0,7916868,"intron_variant",0,0.49,{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.0089,"NR unit increase","Affymetrix, Illumina [~ 10700000] (imputed)","N"]
[27,"rs78689694",11,126243952,"rs11220462","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220462-G","rs11220462",0,11220462,"intron_variant",0,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43564222,"rs144733372","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","ACBD4, ARHGAP27, FMNL1, HEXIM1, HEXIM2, MAP3K14, PLCD3, PLEKHM1, SPATA32","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs144733372-G","rs144733372",1,9899111,"intron_variant",0,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.076714,"NR unit decrease","NR [NR] (imputed)","N"]
[34,"rs16940904",17,43856639,"rs62057061","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs62057061-G","rs62057061",0,62057061,"intron_variant",0,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.02689,"[0.021-0.032] unit increase","Affymetrix [10847151] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":3e-22,"d":"3.00E-22"},21.5228787452803,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.707,{"v":3e-22,"d":"3.00E-22"},21.5228787452803,"(EA)",0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,"NR",{"v":3e-22,"d":"3.00E-22"},21.5228787452803,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-22,"d":"4.00E-22"},21.397940008672,null,0.21751,"[0.17-0.26] unit increase","Affymetrix [7794483] (imputed)","N"]
[17,"rs117026536",8,19847690,"rs10503669","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-C","rs10503669",0,10503669,"intergenic_variant",1,0.9,{"v":4e-22,"d":"4.00E-22"},21.397940008672,null,11.57,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[38,"rs111784051",19,45389596,"rs7254892","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","19q13.32","APOE, APOC1, APOC2","NECTIN2, AC011481.2",null,null,"ENSG00000130202, ENSG00000267114",null,null,"rs7254892-A","rs7254892",0,7254892,"intron_variant",0,0.07,{"v":4e-22,"d":"4.00E-22"},21.397940008672,"(BMI unadjusted)",0.408,"[0.33-0.49] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[21,"rs7924036",10,65010672,"rs10995477","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte count","169,822 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10995477-C","rs10995477",0,10995477,"intron_variant",0,0.4722,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.03472657,"[0.028-0.042] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.2,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.03,"[0.02-0.04] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[2,"rs638714",1,63107526,"rs995000","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.3452,{"v":6e-22,"d":"6.00E-22"},21.2218487496163,null,0.0265,"[0.021-0.032] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Platelet count","108,208 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-22,"d":"6.00E-22"},21.2218487496163,null,0.04103,"[0.033-0.049] unit decrease novel","Illumina [6108953] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","7q11.23","TBL2, MLXIPL, BCL7B","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":7e-22,"d":"7.00E-22"},21.1549019599857,null,0.14,"[0.25-0.53] unit decrease","Affymetrix [389878]","N"]
[37,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":7e-22,"d":"7.00E-22"},21.1549019599857,null,3.11,"[2.37-3.85] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.2288,{"v":8e-22,"d":"8.00E-22"},21.096910013008,null,0.12353132,"[0.098-0.149] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.884,{"v":8e-22,"d":"8.00E-22"},21.096910013008,null,1.14,"[1.11-1.17]","Affymetrix [9149595] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,null,0.13,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[21,"rs7924036",10,65010672,"rs10995477","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10995477-C","rs10995477",0,10995477,"intron_variant",0,0.4723,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,null,0.03441704,"[0.027-0.041] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65162153,"rs7896783","2014-03-14",23969696,"Sabater-Lleal M","2013-08-22","Circulation","www.ncbi.nlm.nih.gov/pubmed/23969696","Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.","Fibrinogen","91,323 European ancestry individuals","8,423 African American individuals, 1,447 Hispanic individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896783-A","rs7896783",0,7896783,"intron_variant",0,0.48,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,"(EA)",0.01,"[0.008-0.012] unit decrease","Affymetrix, Illumina [2515567] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-10-17",28937693,"Clarke TK","2017-07-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28937693","Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).","Alcohol consumption","59,088 European ancestry females, 53,029 European ancestry males","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":1e-21,"d":"1.00E-21"},21,null,0.028,"[0.022-0.034] unit decrease","Affymetrix [12489781] (imputed)","N"]
[15,"rs138574868",7,73042614,"rs7786376","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","7q11.23","MLXIPL, VPS37D","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3741,39541,"rs7786376-?","rs7786376",0,7786376,"intergenic_variant",1,"NR",{"v":1e-21,"d":"1.00E-21"},21,null,0.06432,"[0.051-0.078] unit decrease novel","Illumina [6108953] (imputed)","N"]
[30,"rs72789541",16,15130594,"rs6498540","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","16p13.11","NTAN1, PDXDC1, PLA2G10","PDXDC1",null,null,"ENSG00000179889",null,null,"rs6498540-A","rs6498540",0,6498540,"3_prime_UTR_variant",0,0.6989,{"v":1e-21,"d":"1.00E-21"},21,"(lysoPhosphatidylcholine acyl C20:3)",0.0556,"[0.044-0.067] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":1e-21,"d":"1.00E-21"},21,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27748624,"rs1260333","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2073,11629,"rs1260333-A","rs1260333",0,1260333,"intergenic_variant",1,0.52,{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.022,"[0.018-0.026] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[6,"rs77200710",2,27755825,"rs4665987","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Creatinine levels","142,097 Japanese ancestry individuals","NA","2p23.3","GCKR, C2orf16","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,9274,4428,"rs4665987-?","rs4665987",0,4665987,"intergenic_variant",1,"NR",{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.03616,"[0.029-0.044] unit decrease novel","Illumina [6108953] (imputed)","N"]
[23,"rs61896141",11,61595564,"rs968567","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-T","rs968567",0,968567,"5_prime_UTR_variant",0,0.18,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(dihomo-linolenate (20:3n3 or n6))",0.033,"[0.025-0.041] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(EA)",0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65191645,"rs7924036","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","10q21.3",null,"JMJD1C",null,null,"ENSG00000171988",null,null,"rs7924036-T","rs7924036",0,7924036,"intron_variant",0,0.5124,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.0133,"[0.011-0.016] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[29,"rs55760919",15,58552606,"rs7165301","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7165301-?","rs7165301",0,7165301,"intron_variant",0,"NR",{"v":3e-21,"d":"3.00E-21"},20.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,"(EA)",0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44126765,"rs113434679","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs113434679-C","rs113434679",0,113434679,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.016272,"[0.013-0.02] unit increase","Affymetrix [18485882] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,0.4,{"v":4e-21,"d":"4.00E-21"},20.397940008672,null,0.61,"[0.47-0.75] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Systolic blood pressure","approximately 422,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":4e-21,"d":"4.00E-21"},20.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.209,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,"(Hispanic)",0.173,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2019-01-11",30054458,"Xue A","2018-07-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30054458","Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.","Type 2 diabetes","61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.387154700626533,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,0.0692,"[0.055-0.084] unit decrease","NR [5035015] (imputed)","N"]
[21,"rs7924036",10,65365385,"rs1896995","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Platelet count","108,208 Japanese ancestry individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs1896995-?","rs1896995",0,1896995,"intron_variant",0,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,0.04105,"[0.033-0.05] unit increase novel","Illumina [6108953] (imputed)","N"]
[28,"rs139974673",15,44028047,"rs147233090","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","15q15.3",null,"CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs147233090-?","rs147233090",0,147233090,"intron_variant",0,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,"(EA)",0.048,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs6503451",17,43978988,"rs1560312","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1560312-A","rs1560312",0,1560312,"intron_variant",0,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,9.409,"z score decrease","Affymetrix [10847151] (imputed)","N"]
[6,"rs780110",2,27716004,"rs780088","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Age at menopause","approximately 143,000 European ancestry individuals","NA","2p23.3",null,"FNDC4",null,null,"ENSG00000115226",null,null,"rs780088-?","rs780088",0,780088,"intron_variant",0,"NR",{"v":6e-21,"d":"6.00E-21"},20.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[23,"rs61896141",11,61556039,"rs61896141","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hair color","approximately 452,000 European ancestry individuals","NA","11q12.2",null,"TMEM258",null,null,"ENSG00000134825",null,null,"rs61896141-?","rs61896141",0,61896141,"intron_variant",0,"NR",{"v":6e-21,"d":"6.00E-21"},20.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":6e-21,"d":"6.00E-21"},20.2218487496163,"(EA)",0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-T","rs3764261",0,3764261,"regulatory_region_variant",1,0.34,{"v":7e-21,"d":"7.00E-21"},20.1549019599857,"(mass)",0.0224,"[0.014-0.030] ng/ml increase","Illumina [796174]","N"]
[37,"rs58542926",19,19329924,"rs2228603","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2228603-T","rs2228603",0,2228603,"missense_variant",0,"NR",{"v":7e-21,"d":"7.00E-21"},20.1549019599857,{"$nulls":3},"NR [2501749] (imputed)","N"]
[4,"rs11122450",1,230307222,"rs4846923","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846923-T","rs4846923",0,4846923,"intron_variant",0,"NR",{"v":8e-21,"d":"8.00E-21"},20.096910013008,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21399216,"rs478442","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,33072,22174,"rs478442-?","rs478442",0,478442,"regulatory_region_variant",1,"NR",{"v":8e-21,"d":"8.00E-21"},20.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[29,"rs1601935",15,58671765,"rs1601935","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.36,{"v":8e-21,"d":"8.00E-21"},20.096910013008,null,0.059,"[0.047-0.071] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.685,{"v":8e-21,"d":"8.00E-21"},20.096910013008,"(EA)",0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58727325,"rs261332","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","15q21.3","LIPC, LIPC-AS1","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-T","rs261332",0,261332,"non_coding_transcript_exon_variant",0,0.1955,{"v":9e-21,"d":"9.00E-21"},20.0457574905606,null,2.5879784,"[2.05-3.13] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[4,"rs11122450",1,230304914,"rs10864728","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs10864728-A","rs10864728",0,10864728,"intron_variant",0,"NR",{"v":1e-20,"d":"1.00E-20"},20,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19824563,"rs1059611","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs1059611-?","rs1059611",0,1059611,"3_prime_UTR_variant",0,"NR",{"v":1e-20,"d":"1.00E-20"},20,"(VLDL.medium, fasting)",2.875,"[NR] unit decrease","Illumina [335603]","N"]
[18,"rs2954021",8,126477978,"rs2001945","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-C","rs2001945",0,2001945,"intergenic_variant",1,0.42,{"v":1e-20,"d":"1.00E-20"},20,null,0.0405,"[0.032-0.049] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-20,"d":"1.00E-20"},20,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":1e-20,"d":"1.00E-20"},20,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(LDL.total, fasting)",0.043,"[NR] unit decrease","Illumina [335603]","N"]
[5,"rs562338",2,21286057,"rs515135","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-A","rs515135",0,515135,"intergenic_variant",1,0.19,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.41,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.023,"[0.019-0.027] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[18,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,0.513,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(EA)",0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(EA)",0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.741,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(AA)",0.229,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(AKT2)",0.46390483,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(Apolipoprotein B, APOB.2797.56.2)",0.43,"[0.33-0.53] unit decrease","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-G","rs780094",0,780094,"intron_variant",0,0.63,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,0.1,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[27,"rs78689694",11,126241979,"rs10893499","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs10893499-G","rs10893499",0,10893499,"intron_variant",0,0.876,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,"(EA)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-C","rs4775041",0,4775041,"intron_variant",0,0.33,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,1.38,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[31,"rs3816117",16,57005479,"rs1532624","2010-01-21",20066028,"Igl W","2010-01-08","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20066028","Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels.","Cholesterol","656 European ancestry individuals","Up to 3,282 European ancestry individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,9.99,"[NR] mg/dl increase between hmz","Illumina [~ 311388]","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.892,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,"(AA)",0.381,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.199,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(Hispanic)",0.173,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2010-02-28",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Fasting blood insulin","38,238 European ancestry individuals","62,264 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.032,"[0.024-0.04] pmol/L increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[15,"rs33951980",7,73026378,"rs17145750","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","7q11.23","MLX1PL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-T","rs17145750",0,17145750,"intron_variant",0,0.15,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(VLDL diameter)",0.13,"[0.11-0.15] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[29,"rs490098",15,58694020,"rs16940212","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","15q21.3","LOC101928635","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940212-?","rs16940212",0,16940212,"intron_variant",0,"NR",{"v":4e-20,"d":"4.00E-20"},19.397940008672,{"$nulls":3},"Affymetrix [344366]","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-T","rs5167",0,5167,"missense_variant",0,"NR",{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.6,{"v":5e-20,"d":"5.00E-20"},19.3010299956639,null,0.06,"[0.046-0.074] unit increase","Affymetrix [7947838] (imputed)","N"]
[27,"rs78689694",11,126248211,"rs11220463","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220463-A","rs11220463",0,11220463,"intron_variant",0,0.881,{"v":5e-20,"d":"5.00E-20"},19.3010299956639,"(EA)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":5e-20,"d":"5.00E-20"},19.3010299956639,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43849415,"rs79730878","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","17q21.31","CRHR1-IT1-CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs79730878-T","rs79730878",0,79730878,"intron_variant",0,0.771203,{"v":6e-20,"d":"6.00E-20"},19.2218487496163,null,0.0202142,"[0.016-0.025] unit increase","NR [13737936] (imputed)","N"]
[2,"rs1183851",1,62902874,"rs646179","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","1p31.3",null,"USP1",null,null,"ENSG00000162607",null,null,"rs646179-?","rs646179",0,646179,"5_prime_UTR_variant",0,"NR",{"v":8e-20,"d":"8.00E-20"},19.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,43731719,"rs241036","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs241036-A","rs241036",0,241036,"non_coding_transcript_exon_variant",0,0.217056,{"v":8e-20,"d":"8.00E-20"},19.096910013008,null,9.11,"z score decrease","NR [10847151] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.39,{"v":9e-20,"d":"9.00E-20"},19.0457574905606,null,1.54,"[1.15-1.93] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":1e-19,"d":"1.00E-19"},19,null,0.03308063,"[0.026-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[17,"rs117026536",8,19847690,"rs10503669","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-A","rs10503669",0,10503669,"intergenic_variant",1,0.11,{"v":1e-19,"d":"1.00E-19"},19,"(BMI unadjusted)",0.16,"[0.13-0.19] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":1e-19,"d":"1.00E-19"},19,"(IDL.total, whole)",0.107,"[NR] unit increase","Illumina [335603]","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.685,{"v":1e-19,"d":"1.00E-19"},19,"(EA)",0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs149580368","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","17q21.31","NR","CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs149580368-A","rs149580368",1,112259268,"intergenic_variant",1,0.0254,{"v":1e-19,"d":"1.00E-19"},19,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1e-19,"d":"1.00E-19"},19,"(CTF1)",0.4569444,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[6,"rs1260326",2,27748624,"rs1260333","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2073,11629,"rs1260333-C","rs1260333",0,1260333,"intergenic_variant",1,0.55,{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.05,"[0.04-0.06] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.0556565,"[0.043-0.068] unit increase","Affymetrix [16832071] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.883,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47160953,"rs7241918","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-A","rs7241918",0,7241918,"intergenic_variant",1,0.17,{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,1.94,"[1.43-2.45] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.922,{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,1.15,"[1.12-1.19]","Affymetrix [9149595] (imputed)","N"]
[38,"rs190921611",19,45440529,"rs73045691","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,5886,4966,"rs73045691-?","rs73045691",0,73045691,"intergenic_variant",1,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.03525,"[0.028-0.043] unit decrease novel","Illumina [6108953] (imputed)","N"]
[21,"rs201220977",10,65066186,"rs10761741","2016-12-01",26910538,"Choi SH","2016-02-24","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26910538","Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.","Vascular endothelial growth factor levels","9541 European ancestry individuals, 1,115 Cilento (founder/genetic isolated) individuals, 897 Ogliastran (founder/genetic isolated) individuals, 1,759 Val Borbera (founder/genetic isolated) individuals","2,141 European ancestry individuals, 659 Sorbian (founder/genetic isolated) individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.43,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.08,"[0.062-0.098] unit increase","Affymetrix, Illumina [6705861] (imputed)","N"]
[21,"rs7924036",10,65301725,"rs7897379","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","10q21.3","JMJD1C","REEP3",null,null,"ENSG00000165476",null,null,"rs7897379-T","rs7897379",0,7897379,"intron_variant",0,0.532,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(Trans-ethnic initial)",0.0274,"[0.021-0.034] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.3071,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,{"v":0.0255,"d":"2.55E-02"},"[0.02-0.031] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43569245,"rs113322852","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Neuroticism","523,783 European ancestry individuals","59,206 European ancestry individuals","17q21.31","NR","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,1130,14862,"rs113322852-A","rs113322852",0,113322852,"intergenic_variant",1,0.190284825959502,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.021021854,"[0.016-0.026] unit increase","NR [NR]","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-17",28548082,"Southam L","2017-05-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28548082","Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.","Low density lipoprotein cholesterol levels","up to 1,476 Mylopotamos (founder/genetic isolate) individuals, up to 1,737 Pomak (founder/genetic isolate) individuals","NA","19q13.32","APOC2, APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.079,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.419,"[0.33-0.51] unit decrease","Illumina [at least 13541454] (imputed)","N"]
[23,"rs61896141",11,61547068,"rs7943728","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs7943728-A","rs7943728",0,7943728,"intron_variant",0,"NR",{"v":4e-19,"d":"4.00E-19"},18.397940008672,"(Phosphatidylcholine with acyl-alkyl residue sum C34:2/Phosphatidylcholine with acyl-alkyl residue sum C36:3)",0.484582,"[0.38-0.59] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[34,"rs16940904",17,43659975,"rs2668680","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","17q21.31","NR","AC091132.4 - DND1P1","ENSG00000267198","ENSG00000282614",null,19379,3262,"rs2668680-C","rs2668680",0,2668680,"intron_variant",1,0.177,{"v":4e-19,"d":"4.00E-19"},18.397940008672,null,0.0174888,"[0.014-0.021] unit decrease","NR [~ 9732723] (imputed)","N"]
[4,"rs11122450",1,230304914,"rs10864728","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs10864728-A","rs10864728",0,10864728,"intron_variant",0,0.387,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230305312,"rs1321257","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs1321257-G","rs1321257",0,1321257,"intron_variant",0,0.387,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,"NR",{"v":5e-19,"d":"5.00E-19"},18.3010299956639,null,0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,"(EA)",0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21274167,"rs13011615","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,7222,72622,"rs13011615-?","rs13011615",0,13011615,"intergenic_variant",1,"NR",{"v":6e-19,"d":"6.00E-19"},18.2218487496163,"(Free cholesterol in large LDL, conditioned)",0.1247424,"[0.097-0.152] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[15,"rs62466318",7,73037366,"rs55747707","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs55747707-A","rs55747707",0,55747707,"intron_variant",0,0.1796,{"v":6e-19,"d":"6.00E-19"},18.2218487496163,null,0.0314,"[0.025-0.038] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":8e-19,"d":"8.00E-19"},18.096910013008,"(EA)",0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":8e-19,"d":"8.00E-19"},18.096910013008,null,0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-09-12",20838585,"Smith EN","2010-09-09","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20838585","Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.","Cardiovascular risk factors","525 European ancestry individuals","2,442 Finnish ancestry individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":9e-19,"d":"9.00E-19"},18.0457574905606,"(LDL-cholesterol)",11.96,"[9.33-14.59] unit increase","Illumina [2173391] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":1e-18,"d":"1.00E-18"},18,null,0.03246703,"[0.025-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[23,"rs61896141",11,61595564,"rs968567","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS2, FADS1, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-T","rs968567",0,968567,"5_prime_UTR_variant",0,0.1587,{"v":1e-18,"d":"1.00E-18"},18,"(lysoPhosphatidylcholine acyl C20:3)",0.0675,"[0.052-0.083] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,0.969,{"v":1e-18,"d":"1.00E-18"},18,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":1e-18,"d":"1.00E-18"},18,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.716,{"v":1e-18,"d":"1.00E-18"},18,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44248769,"rs1881193","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs1881193-T","rs1881193",0,1881193,"missense_variant",0,0.21737,{"v":1e-18,"d":"1.00E-18"},18,null,8.84,"z score decrease","NR [10847151] (imputed)","N"]
[34,"rs16940904",17,44357351,"rs17665188","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs17665188-T","rs17665188",0,17665188,"intron_variant",0,0.213949,{"v":1e-18,"d":"1.00E-18"},18,null,8.79,"z score decrease","NR [10847151] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.223,{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(Four-jointed box protein 1, FJX1.7921.65.3)",0.26,"[0.2-0.32] unit decrease","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.03202804,"[0.025-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[17,"rs117026536",8,19830921,"rs10096633","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-G","rs10096633",0,10096633,"regulatory_region_variant",1,0.88,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.17,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[18,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,0.485,{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.031,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[34,"rs16940904",17,44787312,"rs1378358","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Neuroticism","523,783 European ancestry individuals","59,206 European ancestry individuals","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs1378358-T","rs1378358",0,1378358,"intron_variant",0,0.217292507620124,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.019632332,"[0.015-0.024] unit increase","NR [NR]","N"]
[35,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Metabolite levels","8,330 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(Ala, Gln)",0.15,"[0.11-0.19] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[10,"rs272863",5,131633355,"rs419291","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","SLC22A4",null,null,"ENSG00000197208",null,null,"rs419291-T","rs419291",0,419291,"intron_variant",0,0.37,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(carnitine)",0.008,"[0.006-0.01] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[17,"rs117026536",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.89,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(BMI unadjusted)",0.165,"[0.13-0.2] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[21,"rs201220977",10,65050659,"rs7075195","2014-03-25",24026423,"Shameer K","2013-09-12","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/24026423","A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.","Mean platelet volume","6,291 European ancestry individuals","NA","10q21.3","JMJD1C, NRBF2, REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7075195-A","rs7075195",0,7075195,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.13,"[NR] unit increase","Illumina [476395]","N"]
[29,"rs16940168",15,58687790,"rs495348","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","15q21.3","LOC101928635","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs495348-?","rs495348",0,495348,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,{"$nulls":3},"Affymetrix [344366]","N"]
[35,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(APOB.assay, fasting)",4.492,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs9304381",18,47160953,"rs7241918","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.19,{"v":4e-18,"d":"4.00E-18"},17.397940008672,null,0.058,"[NR] unit decrease","NR [NR] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":5e-18,"d":"5.00E-18"},17.3010299956639,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44773783,"rs199441","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199441-A","rs199441",0,199441,"intron_variant",0,0.217502,{"v":6e-18,"d":"6.00E-18"},17.2218487496163,null,8.63,"z score increase","NR [10847151] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,"NR",{"v":6e-18,"d":"6.00E-18"},17.2218487496163,null,0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":8e-18,"d":"8.00E-18"},17.096910013008,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[12,"rs6931604",6,98578215,"rs6931604","2018-09-12",29942086,"Savage JE","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942086","Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.","Intelligence","269,867 European ancestry individuals","NA","6q16.1","NR","AL589740.1",null,null,"ENSG00000271860",null,null,"rs6931604-T","rs6931604",0,6931604,"intron_variant",0,"NR",{"v":8e-18,"d":"8.00E-18"},17.096910013008,null,8.606,"z-score increase","Affymetrix, Illumina [9295118] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":8e-18,"d":"8.00E-18"},17.096910013008,"(CKAP2)",0.429486,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":9e-18,"d":"9.00E-18"},17.0457574905606,"(EA)",0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":9e-18,"d":"9.00E-18"},17.0457574905606,null,0.05598592,"[0.043-0.069] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":1e-17,"d":"1.00E-17"},17,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-C","rs2144300",0,2144300,"intron_variant",0,0.397,{"v":1e-17,"d":"1.00E-17"},17,"(EA)",0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.13","NR","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,0.397,{"v":1e-17,"d":"1.00E-17"},17,"(EA)",0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,72877166,"rs2074755","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2074755-?","rs2074755",0,2074755,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-17,"d":"1.00E-17"},17,{"$nulls":3},"Affymetrix [NR]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.087,{"v":1e-17,"d":"1.00E-17"},17,"(EA)",0.07,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.588,{"v":1e-17,"d":"1.00E-17"},17,"(East Asian)",0.116,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44192568,"rs4630591","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling fed-up","374,971 European ancestry individuals","NA","17q21.31","ACBD4","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs4630591-T","rs4630591",0,4630591,"intron_variant",0,0.198844,{"v":1e-17,"d":"1.00E-17"},17,null,8.54,"z score increase","NR [10847151] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0169,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.36090583,"[0.28-0.44] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-09-19",29748315,"Pott J","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29748315","Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes.","Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease","2,022 European ancestry individuals without statin treatment, 1,268 European ancestry individuals with statin treatment","NR","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0121655389057751,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.315,"[0.24-0.39] unit decrease","Affymetrix [9882017] (imputed)","N"]
[2,"rs638714",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.5895,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.064,"[0.048-0.08] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[11,"rs59136961",6,34769765,"rs4472337","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs4472337-T","rs4472337",0,4472337,"intron_variant",0,0.1616,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.04212671,"[0.032-0.052] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[23,"rs174468",11,61663691,"rs174468","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","RAB3IL1","FADS3 - RAB3IL1","ENSG00000221968","ENSG00000167994",null,4168,1082,"rs174468-A","rs174468",0,174468,"regulatory_region_variant",1,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.05,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.596,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(East Asian)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.164,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(EA)",0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62960250,"rs1168041","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipid measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168041-C","rs1168041",0,1168041,"non_coding_transcript_exon_variant",0,0.72,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(serum total triglycerides)",0.1,"[0.08-0.12] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.915,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(Hispanic)",0.204,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.89,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(East Asian)",0.194,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs7943992",11,61272565,"rs7125196","2018-10-18",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption interaction (2df test)","63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers,  2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers","11q12.2","LOC105369329, MIR4488","AP003108.1 - MIR4488","ENSG00000255931","ENSG00000266006",null,5017,3503,"rs7125196-T","rs7125196",0,7125196,"intergenic_variant",1,0.77,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(Asian, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[27,"rs78689694",11,126241979,"rs10893499","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs10893499-G","rs10893499",0,10893499,"intron_variant",0,"NR",{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,0.054,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44856641,"rs199515","2012-04-20",22451204,"Pankratz N","2012-03-01","Ann Neurol","www.ncbi.nlm.nih.gov/pubmed/22451204","Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.","Parkinson's disease","4,238 European ancestry cases, 4,239 European ancestry controls","3,738 European ancestry cases, 2,111 European ancestry controls","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199515-?","rs199515",0,199515,"intron_variant",0,"NR",{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,1.32,"[NR]","Illumina [2500000] (imputed)","N"]
[35,"rs9304381",18,47172283,"rs2187375","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,46731,4437,"rs2187375-A","rs2187375",0,2187375,"intergenic_variant",1,0.17,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(X-03094)",0.022,"[0.016-0.028] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2010-10-15",20884846,"Yang Q","2010-09-30","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20884846","Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.","Urate levels","28,283 European ancestry individuals","22,054 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":4e-17,"d":"4.00E-17"},16.397940008672,"(Urate)",5.15,"[3.95-6.35] umol/l increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131694077,"rs4705938","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FVC)","approximately 372,000 European ancestry individuals","NA","5q31.1",null,"MIR3936HG",null,null,"ENSG00000233006",null,null,"rs4705938-?","rs4705938",0,4705938,"intron_variant",0,"NR",{"v":4e-17,"d":"4.00E-17"},16.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[18,"rs2954021",8,126486409,"rs17321515","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-G","rs17321515",0,17321515,"intron_variant",0,0.49,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.08,"[0.06-0.10] unit decrease","Affymetrix [389878]","N"]
[18,"rs112875651",8,126506694,"rs112875651","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-A","rs112875651",0,112875651,"intron_variant",0,0.3925,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.03120159,"[0.024-0.038] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs525028",11,116705516,"rs525028","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","11q23.3","NR","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,1728,951,"rs525028-?","rs525028",0,525028,"intergenic_variant",1,"NR",{"v":4e-17,"d":"4.00E-17"},16.397940008672,"(conditional on round 4)",0.05190519,"[0.04-0.064] unit decrease novel","Illumina [6108953] (imputed)","N"]
[27,"rs78689694",11,126243952,"rs11220462","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220462-G","rs11220462",0,11220462,"intron_variant",0,"NR",{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":5e-17,"d":"5.00E-17"},16.3010299956639,"(ER membrane protein complex subunit 4, EMC4.13516.46.3)",0.39,"[0.29-0.49] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.1837,{"v":6e-17,"d":"6.00E-17"},16.2218487496163,null,0.0555,"[0.043-0.068] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[27,"rs78689694",11,126248211,"rs11220463","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","11q24.2","ST3GAL4","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220463-A","rs11220463",0,11220463,"intron_variant",0,"NR",{"v":6e-17,"d":"6.00E-17"},16.2218487496163,{"$nulls":3},"NR [2501749] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.308,{"v":7e-17,"d":"7.00E-17"},16.1549019599857,"(Hispanic)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":8e-17,"d":"8.00E-17"},16.096910013008,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or large artery stroke","2,167 Large artery stroke cases, 22,233 Coronary artery disease cases, ~ 75,921 controls","NA","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-?","rs599839",0,599839,"regulatory_region_variant",1,null,{"v":8e-17,"d":"8.00E-17"},16.096910013008,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":8e-17,"d":"8.00E-17"},16.096910013008,null,0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11188153,"rs55791371","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs55791371-?","rs55791371",0,55791371,"intron_variant",0,"NR",{"v":8e-17,"d":"8.00E-17"},16.096910013008,"(M-LDL-C/M-LDL-PL)",0.26,"[0.2-0.32] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[38,"rs34827707",19,45541782,"rs34827707","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19q13.32","NR","RELB - CLASRP","ENSG00000104856","ENSG00000104859",null,326,516,"rs34827707-A","rs34827707",0,34827707,"regulatory_region_variant",1,0.0340516,{"v":9e-17,"d":"9.00E-17"},16.0457574905606,null,0.272045,"[0.21-0.34] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[4,"rs11122450",1,230307222,"rs4846923","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846923-G","rs4846923",0,4846923,"intron_variant",0,0.71,{"v":1e-16,"d":"1.00E-16"},16,null,0.055,"[0.041-0.069] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[11,"rs59136961",6,34603646,"rs2492863","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p21.31","C6orf106, SNRPC, UHRF1BP1","C6orf106",null,null,"ENSG00000196821",null,null,"rs2492863-A","rs2492863",0,2492863,"intron_variant",0,0.139616,{"v":1e-16,"d":"1.00E-16"},16,"(females)",0.03596,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[12,"rs6931604",6,98578215,"rs6931604","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","6q16.1","RP11-436D23.1","AL589740.1",null,null,"ENSG00000271860",null,null,"rs6931604-T","rs6931604",0,6931604,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,8.266,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (small molecules and protein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-G","rs2169387",0,2169387,"intron_variant",0,0.87,{"v":1e-16,"d":"1.00E-16"},16,"(Glycine)",0.13,"[0.091-0.169] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.909,{"v":1e-16,"d":"1.00E-16"},16,"(Hispanic)",0.196,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs78689694",11,126248211,"rs11220463","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220463-A","rs11220463",0,11220463,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.053,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723939,"rs2070895","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","15q21.3",null,"ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs112557952",17,43836953,"rs56214516","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling fed-up","374,971 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs56214516-A","rs56214516",0,56214516,"intron_variant",0,0.189219,{"v":1e-16,"d":"1.00E-16"},16,null,8.27,"z score decrease","NR [10847151] (imputed)","N"]
[34,"rs6503451",17,43978988,"rs1560312","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1560312G","rs1560312",0,1560312,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.02016,"[0.015-0.025] unit increase","Affymetrix [10847151] (imputed)","N"]
[6,"rs1728918",2,27635463,"rs1728918","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","2p23.3","intergenic","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(mannose)",0.04006,"[NR] unit decrease","Affymetrix [655658]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Blood sugar levels","93,146 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.03854,"[0.029-0.048] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(Men + Women)",0.032,"[0.024-0.040] nmol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2017-07-06",28452372,"Gorski M","2017-04-28","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28452372","1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.","Glomerular filtration rate (creatinine)","110,517 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.0081,"[0.0063-0.0099] unit increase","Affymetrix, Illumina [up to 10971307] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131722951,"rs274555","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","5q31.1","NR","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274555-?","rs274555",0,274555,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.18633,"[0.14-0.23] unit decrease","Affymetrix [7794483] (imputed)","N"]
[15,"rs62466318",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.03673838,"[0.028-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[27,"rs78689694",11,126244955,"rs4307732","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs4307732-G","rs4307732",0,4307732,"non_coding_transcript_exon_variant",0,0.901,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(EA)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.04,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43915497,"rs62054807","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","CRHR1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs62054807-C","rs62054807",0,62054807,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.014157,"[0.011-0.018] unit increase","Affymetrix [18485882] (imputed)","N"]
[34,"rs16940904",17,44192618,"rs4606752","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs4606752-G","rs4606752",0,4606752,"intron_variant",0,0.2267,{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.03470527,"[0.026-0.043] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs58542926",19,19366632,"rs72999033","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"HAPLN4, AC138430.1, AC138430.2",null,null,"ENSG00000187664, ENSG00000267629, ENSG00000280282",null,null,"rs72999033-?","rs72999033",0,72999033,"3_prime_UTR_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.174,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Hispanic)",0.161,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.03656896,"[0.028-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-G","rs2169387",0,2169387,"intron_variant",0,0.89,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.083,"[0.063-0.103] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.891,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(East Asian)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.48,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Triglycerides in very small VLDL)",0.09,"[0.07-0.11] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[30,"rs11644601",16,15172118,"rs11644601","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","RRN3, PDXDC1",null,null,"ENSG00000085721, ENSG00000179889",null,null,"rs11644601-T","rs11644601",0,11644601,"intron_variant",0,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.298,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Hispanic)",0.0509,"[NR] unit increase","Affymetrix [NR]","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.041,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44837217,"rs199529","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","NSF","NSF - WNT3","ENSG00000073969","ENSG00000277641",null,2387,2655,"rs199529-A","rs199529",0,199529,"intergenic_variant",1,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.014192,"[0.011-0.018] unit increase","Affymetrix [18485882] (imputed)","N"]
[5,"rs7419374",2,21319016,"rs672889","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,52071,27773,"rs672889-G","rs672889",0,672889,"intergenic_variant",1,0.1356,{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.1294899,"[0.098-0.161] mg/dl increase","Illumina [24111857] (imputed)","N"]
[5,"rs562338",2,21399216,"rs478442","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,33072,22174,"rs478442-?","rs478442",0,478442,"regulatory_region_variant",1,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.64,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(East Asian)",0.113,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(IDL.total, fasting)",0.112,"[NR] unit increase","Illumina [335603]","N"]
[35,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(KLRC3)",0.4164335,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[11,"rs59136961",6,34603646,"rs2492863","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p21.31","C6orf106, SNRPC, UHRF1BP1","C6orf106",null,null,"ENSG00000196821",null,null,"rs2492863-A","rs2492863",0,2492863,"intron_variant",0,0.139616,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,0.02467,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(EA)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15129970,"rs7200543","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs7200543-G","rs7200543",0,7200543,"synonymous_variant",0,0.304,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(SM-15 + 12 other traits)",0.073,"[NR] unit decrease","Affymetrix, Illumina [534665]","N"]
[31,"rs3764261",16,56988044,"rs173539","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,0.26,"[0.20-0.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[35,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(EA)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(Low-density lipoprotein receptor-related protein 1B, LRP1B.7640.29.3)",0.37,"[0.27-0.47] unit decrease","Affymetrix [10572788] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,0.096,{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(EA)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.875,{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(East Asian)",0.178,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43728376,"rs417968","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Educational attainment (years of education)","approximately 455,000 European ancestry individuals","NA","17q21.31",null,"LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs417968-?","rs417968",0,417968,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-16,"d":"6.00E-16"},15.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs71279459",17,43777313,"rs1724422","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs1724422-A","rs1724422",0,1724422,"intron_variant",0,"NR",{"v":6e-16,"d":"6.00E-16"},15.2218487496163,null,8.092,"z score decrease","Affymetrix [10847151] (imputed)","N"]
[35,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.987,{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(EA)",0.166,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131590534,"rs7727544","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","P4HA2",null,null,"ENSG00000072682",null,null,"rs7727544-T","rs7727544",0,7727544,"intron_variant",0,0.56,{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(propionylcarnitine)",0.015,"[0.011-0.019] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[10,"rs272863",5,131699867,"rs274546","2012-10-24",20881960,"Lango Allen H","2010-09-29","Nature","www.ncbi.nlm.nih.gov/pubmed/20881960","Hundreds of variants clustered in genomic loci and biological pathways affect human height.","Height","133,653 European ancestry individuals","50,074 European ancestry individuals","5q31.1","SLC22A5","MIR3936HG",null,null,"ENSG00000233006",null,null,"rs274546-A","rs274546",0,274546,"intron_variant",0,0.4,{"v":7e-16,"d":"7.00E-16"},15.1549019599857,null,0.029,"[NR] unit decrease","Affymetrix, Illumina [2834208] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum alkaline phosphatase levels","105,030 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,null,0.03517,"[0.027-0.044] unit decrease novel","Illumina [6108953] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(HDL-C.by.NMR, whole)",1.513,"[NR] unit decrease","Illumina [335603]","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(Disintegrin and metalloproteinase domain-containing protein 11, ADAM11.6586.19.3)",0.37,"[0.27-0.47] unit decrease","Affymetrix [10572788] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131656997,"rs270601","2016-06-01",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Acylcarnitine levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","5q31.1","SLC22A4, SLC22A5","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs270601-T","rs270601",0,270601,"intron_variant",0,0.2979,{"v":8e-16,"d":"8.00E-16"},15.096910013008,"(Octadecenoylcarnitine)",0.0433,"[0.033-0.054] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[15,"rs62466318",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.03591725,"[0.027-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs11644601",16,15172118,"rs11644601","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","RRN3, PDXDC1",null,null,"ENSG00000085721, ENSG00000179889",null,null,"rs11644601-T","rs11644601",0,11644601,"intron_variant",0,0.703,{"v":8e-16,"d":"8.00E-16"},15.096910013008,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47176261,"rs6507939","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,50709,459,"rs6507939-C","rs6507939",0,6507939,"intergenic_variant",1,0.84,{"v":8e-16,"d":"8.00E-16"},15.096910013008,"(HDL diameter)",0.11,"[0.09-0.13] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.178,{"v":1e-15,"d":"1.00E-15"},15,"(Hispanic)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Type 2 diabetes","approximately 459,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.617,{"v":1e-15,"d":"1.00E-15"},15,null,1.06,"[1.04-1.07]","Affymetrix, Illumina [247470]","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,null,0.057,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.4184,{"v":1e-15,"d":"1.00E-15"},15,null,0.02902436,"[0.022-0.036] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[27,"rs78689694",11,126243952,"rs11220462","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220462-G","rs11220462",0,11220462,"intron_variant",0,0.88,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43726625,"rs150844304","2017-02-24",27036123,"van Leeuwen EM","2016-04-01","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/27036123","Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.","Triglycerides","41,142 European ancestry individuals, 705 East Asian ancestry individuals, 6,287 African American individuals, 1,415 Hispanic individuals","60,827 European ancestry individuals, 9,982 Indian Asian ancestry individuals, 2,710 African American/Afro-Caribbean individuals","15q15.3","TP53BP1","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,0.96,{"v":1e-15,"d":"1.00E-15"},15,null,0.066,"[0.05-0.082] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[30,"rs72789541",16,15131974,"rs1136001","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","16p13.11","PDXDC1, NTAN1, C16orf45, KIAA0430, MYH11, NDEI, RRN3, PARN","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs1136001-T","rs1136001",0,1136001,"missense_variant",0,0.309,{"v":1e-15,"d":"1.00E-15"},15,null,0.35,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[35,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,0.164,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs778356958",1,63199936,"rs6679002","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","1p31.3","ANGPTL3","AC103923.1 - ATG4C","ENSG00000235545","ENSG00000125703",null,23571,49870,"rs6679002-T","rs6679002",0,6679002,"TF_binding_site_variant",1,0.59,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(X-03094)",0.014,"[0.01-0.018] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.177,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Hispanic)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs780110",2,27716494,"rs704795","2018-02-21",26414677,"Day FR","2015-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26414677","Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.","Menopause (age at onset)","up to 69,626 European ancestry women","NA","2p23.3","BRE, GTF3C2, EIFB4","FNDC4",null,null,"ENSG00000115226",null,null,"rs704795-A","rs704795",0,704795,"intron_variant",0,0.4,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.16,"[0.12-0.2] years decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[16,"rs7012637",8,9173209,"rs7012637","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs7012637-G","rs7012637",0,7012637,"intron_variant",0,0.525,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(conditional)",null,null,"Affymetrix, Illumina [NR] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.917,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Hispanic)",0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"10:22255616_CT_C",10,22285371,"rs4364959","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","10p12.31","NR","DNAJC1",null,null,"ENSG00000136770",null,null,"rs4364959-?","rs4364959",0,4364959,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[27,"rs78689694",11,126241979,"rs10893499","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs10893499-G","rs10893499",0,10893499,"intron_variant",0,0.876,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs78689694",11,126248211,"rs11220463","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs11220463-A","rs11220463",0,11220463,"intron_variant",0,0.881,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44364649,"rs2696497","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling fed-up","374,971 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2696497-T","rs2696497",0,2696497,"intron_variant",0,0.21384,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,7.92,"z score increase","NR [10847151] (imputed)","N"]
[35,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47179516,"rs1943973","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,1986,86677,"rs1943973-?","rs1943973",0,1943973,"regulatory_region_variant",1,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.04347,"[0.033-0.054] unit decrease novel","Illumina [6108953] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11882123",19,19657632,"rs7245983","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","19p13.11","CILP2","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,164,14884,"rs7245983-C","rs7245983",0,7245983,"intergenic_variant",1,0.3445,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.02971055,"[0.022-0.037] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.15,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2010-05-26",20442857,"Suchindran S","2010-04-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20442857","Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.","Lipoprotein-associated phospholipase A2 activity and mass","6,668 European ancestry individuals","NA","1p13.3","PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.22,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(activity)",5.5,"[NR] nmol/ml/min decrease","Affymetrix [360811]","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Triglycerides","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.356,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(Hispanic)",0.108,"[0.081-0.135] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[15,"rs62466318",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.03519386,"[0.026-0.044] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.056,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs546735951",17,43474668,"rs62064598","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","ENSG00000267344","AC003070.1, ARHGAP27, ARHGAP27, ARHGAP27",null,null,"ENSG00000267344, ENSG00000276836, ENSG00000276907, ENSG00000159314",null,null,"rs62064598-C","rs62064598",0,62064598,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.013541,"[0.01-0.017] unit increase","Affymetrix [18485882] (imputed)","N"]
[34,"rs16940904",17,43569909,"rs146746174","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Self-reported math ability (MTAG)","670,471 European ancestry individuals","NA","17q21.31","Intergenic","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,1794,14198,"rs146746174-T","rs146746174",1,62065449,"intergenic_variant",1,0.8153,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(MTAG)",0.0182,"[0.014-0.023] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Triglyceride levels in small VLDL","8,372 Finnish ancestry males","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-?","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,null,0.2,"unit decrease","Illumina [15144991] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.392,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(East Asian)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs35076622",17,43854655,"rs34186148","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs34186148-C","rs34186148",0,34186148,"intron_variant",0,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,null,7.869,"z score increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs16940904",17,44038785,"rs62063281","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Number of sexual partners","370,711 European ancestry individuals","NA","17q21.31","STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62063281-A","rs62063281",0,62063281,"intron_variant",0,0.7784,{"v":4e-15,"d":"4.00E-15"},14.397940008672,null,0.022359965,"[0.017-0.028] unit increase","Affymetrix [11515109] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19849757,"rs17091905","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,24987,86868,"rs17091905-A","rs17091905",0,17091905,"intergenic_variant",1,0.12,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(TRIG)",0.174,"[0.13-0.22] mmol/l decrease","Illumina [NR] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.399,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(East Asian)",0.105,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs11644601",16,15150505,"rs12928099","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16p13.11","intergenic","PDXDC1",null,null,"ENSG00000179889",null,null,"rs12928099-A","rs12928099",0,12928099,"intron_variant",0,0.2698,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.0253,"[0.019-0.032] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[34,"rs6503451",17,43992943,"rs9899833","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs9899833-G","rs9899833",0,9899833,"intron_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.013529,"[0.01-0.017] unit increase","Affymetrix [18485882] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1162,{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.0307,"[0.021-0.04] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[34,"rs16940904",17,43810896,"rs77804065","2018-03-01",29397368,"Meng W","2018-01-31","EBioMedicine","www.ncbi.nlm.nih.gov/pubmed/29397368","A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).","Headache","74,461 British ancestry cases, 149,321 British ancestry controls","NA","17q21.31","LINC02210, CRHR1, MAPT","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,"NR",{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.013,"[0.0097-0.0163] unit increase","Affymetrix [9304965] (imputed)","N"]
[34,"rs16940904",17,43940021,"rs79412431","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","Peak expiratory flow","321,047 European ancestry individuals","24,218 European ancestry individuals","17q21.31","MAPT-AS1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs79412431-A","rs79412431",0,79412431,"intron_variant",0,0.2161,{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.0239,"[0.018-0.03] unit decrease","Affymetrix [19819130] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,0.776,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(Neogenin, NEO1.8900.28.3)",0.23,"[0.17-0.29] unit decrease","Affymetrix [10572788] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Ratio of apolipoprotein A1 to apolipoprotein B","8,372 Finnish ancestry males","NA","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-?","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.151,"unit increase","Illumina [15144991] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2008-06-22",18439548,"Ridker PM","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439548","Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.","C-reactive protein","6,345 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-A","rs780094",0,780094,"intron_variant",0,"NR",{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.14,"[NR] mg/dl increase","Illumina [336108]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-T","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,2.22,"[1.65-2.79] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[35,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,0.17,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.17,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.14,"[0.10-0.18] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[2,"rs638714",1,62950858,"rs10889332","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889332-?","rs10889332",0,10889332,"3_prime_UTR_variant",0,0.29,{"v":8e-15,"d":"8.00E-15"},14.096910013008,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[34,"rs16940904",17,44187257,"rs9303525","2012-06-01",22504418,"Ikram MA","2012-04-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22504418","Common variants at 6q22 and 17q21 are associated with intracranial volume.","Intracranial volume","8,175 European ancestry individuals","1,752 European ancestry individuals","17q21.31","MAPT, GRN, CRHR1, STH","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs9303525-G","rs9303525",0,9303525,"intron_variant",0,0.22,{"v":8e-15,"d":"8.00E-15"},14.096910013008,null,14.9,"[NR] ml decrease","Affymetrix, Illumina [2229753] (imputed)","N"]
[15,"rs33951980",7,73052057,"rs799165","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,13184,30098,"rs799165-?","rs799165",0,799165,"intergenic_variant",1,"NR",{"v":9e-15,"d":"9.00E-15"},14.0457574905606,{"$nulls":3},"Affymetrix [NR]","N"]
[18,"rs2954021",8,126482077,"rs2954021","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte percentage of white cells","171,748 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5053,{"v":9e-15,"d":"9.00E-15"},14.0457574905606,null,0.02756497,"[0.021-0.035] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":9e-15,"d":"9.00E-15"},14.0457574905606,"(HDL-C.assay, fasting)",1.421,"[NR] unit increase","Illumina [335603]","N"]
[2,"rs638714",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,"(VLDL.total, whole)",2.973,"[NR] unit decrease","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.617,{"v":1E-14,"d":"1.00E-14"},14,null,1.05,"[1.04-1.07]","Affymetrix, Illumina [247470]","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.909,{"v":1E-14,"d":"1.00E-14"},14,"(Hispanic)",0.165,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.49,{"v":1E-14,"d":"1.00E-14"},14,"(HDL)",0.14,"[0.1-0.18] unit decrease","Illumina [561583]","N"]
[33,"rs72836561",17,41840849,"rs77697917","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","17q21.31","SOST, DUSP3","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-C","rs77697917",0,77697917,"intergenic_variant",1,0.97,{"v":1E-14,"d":"1.00E-14"},14,null,0.176,"[0.13-0.22] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[34,"rs16940904",17,44828931,"rs199533","2009-12-10",19915575,"Simon-Sanchez J","2009-11-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19915575","Genome-wide association study reveals genetic risk underlying Parkinson's disease.","Parkinson's disease","1,713 European ancestry cases, 3,978 European ancestry controls","3,361 European ancestry cases, 4,573 European ancestry controls","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199533-C","rs199533",0,199533,"synonymous_variant",0,0.83,{"v":1E-14,"d":"1.00E-14"},14,null,1.28,"[NR]","Illumina [463185]","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.897,{"v":1E-14,"d":"1.00E-14"},14,"(Hispanic)",0.193,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-03-28",30510157,"Franceschini N","2018-12-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30510157","GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.","Carotid intima media thickness","Up to 71,128 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.08,{"v":1E-14,"d":"1.00E-14"},14,null,0.0119,"[0.009-0.0148] unit decrease","Affymetrix, Illumina [9574088] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(HDL)",0.04,"[0.020-0.060] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.915,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(Hispanic)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65315800,"rs7919685","2018-08-13",29892015,"Roselli C","2018-06-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29892015","Multi-ethnic genome-wide association study for atrial fibrillation.","Atrial fibrillation","55,114 European ancestry cases, 482,295 European ancestry controls, 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls, 1,307 African American ancestry cases, 7,660 African American ancestry controls, 845 Hispanic cases, 4,177 Hispanic controls","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs7919685-G","rs7919685",0,7919685,"intron_variant",0,0.52,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(EA)",1.06,"[1.04-1.08]","Affymetrix, Illumina [up to 12149979] (imputed)","N"]
[23,"rs174477",11,61678754,"rs174479","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Sphingolipid levels","4,034 European ancestry individuals","NA","11q12.3","FADS1, FADS2, FADS3","RAB3IL1",null,null,"ENSG00000167994",null,null,"rs174479-?","rs174479",0,174479,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(levels)",0,"[0.80-1.50] % increase","Illumina [NR] (imputed)","N"]
[29,"rs1077835",15,58723426,"rs1077835","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-G","rs1077835",0,1077835,"intron_variant",0,0.22,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.059,"[0.043-0.075] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-?","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(HDL.total, fasting)",0.742,"[NR] unit decrease","Illumina [335603]","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.756,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(AA)",0.227,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-T","rs2144300",0,2144300,"intron_variant",0,0.6,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,1.11,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum albumin level","Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.0124,"[0.0093-0.0155] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-11-25",26831199,"Pattaro C","2016-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26831199","Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.","Glomerular filtration rate (creatinine)","133,413 European ancestry individuals","42,166 European ancestry individuals, up to 16,471 African ancestry individuals, up to 42,296 Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.42,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.0068,"[0.005-0.0086] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,{"$nulls":3},"NR [25015711] (imputed)","N"]
[17,"rs117026536",8,19928582,"rs9644568","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103812,8043,"rs9644568-A","rs9644568",0,9644568,"intergenic_variant",1,0.254704,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.12829615,"[0.095-0.161] mg/dl increase","Illumina [24111857] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.548,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(East Asian)",0.102,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.38,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.018,"[0.014-0.022] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[34,"rs16940904",17,43923683,"rs12185268","2011-07-20",21738487,"Do CB","2011-06-23","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21738487","Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.","Parkinson's disease","3,426 European ancestry cases, 29,624 European ancestry controls","NA","17q21.31","MAPT","MAPT-AS1, MAPT-AS1, MAPT-AS1, SPPL2C, SPPL2C, SPPL2C",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000277106, ENSG00000185294, ENSG00000278194",null,null,"rs12185268-A","rs12185268",0,12185268,"missense_variant",0,0.79,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,1.3,"[1.22-1.39]","Illumina [522782]","N"]
[38,"rs7412",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(Interleukin-22 receptor subunit alpha-1, IL22RA1.3620.67.2)",0.35,"[0.25-0.45] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs562338",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.175,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.148,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.174,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.149,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs673335",11,75450576,"rs673335","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","11q13.5",null,"MOGAT2 - RN7SL786P","ENSG00000166391","ENSG00000263993",null,6573,2598,"rs673335-?","rs673335",0,673335,"intergenic_variant",1,"NR",{"v":4E-14,"d":"4.00E-14"},13.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs488490",15,58742418,"rs261336","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","15q21.3","LIPC, LIPC-AS1","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261336-C","rs261336",0,261336,"intron_variant",0,0.1795,{"v":4E-14,"d":"4.00E-14"},13.397940008672,null,2.2511744,"[1.67-2.83] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":5e-14,"d":"5.00E-14"},13.3010299956639,null,0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136806959,"rs925966","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","2q21.3",null,"DARS-AS1 - AC068492.1","ENSG00000231890","ENSG00000237262",null,26796,28503,"rs925966-?","rs925966",0,925966,"intergenic_variant",1,"NR",{"v":5e-14,"d":"5.00E-14"},13.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[17,"rs117026536",8,19843171,"rs17091891","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,18401,93454,"rs17091891-T","rs17091891",0,17091891,"intergenic_variant",1,0.8709,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,null,0.0585,"[0.043-0.074] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[23,"rs61896141",11,61595564,"rs968567","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-T","rs968567",0,968567,"5_prime_UTR_variant",0,"NR",{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(Phosphatidylcholine with diacyl residue sum C42:0/Phosphatidylcholine with acyl-alkyl residue sum C44:6)",0.395747,"[0.29-0.5] unit increase","Illumina [up to 9281895] (imputed)","N"]
[2,"rs1183851",1,62902874,"rs646179","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","1p31.3",null,"USP1",null,null,"ENSG00000162607",null,null,"rs646179-?","rs646179",0,646179,"5_prime_UTR_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.183,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(Hispanic)",0.146,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(alanine)",0.013,"[0.0091-0.0169] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[18,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,0.758,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(EA)",0.042,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs78689694",11,126232337,"rs4055121","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q24.2","ST3GAL4","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs4055121-T","rs4055121",0,4055121,"intron_variant",0,0.14,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(Immunoglobulin superfamily containing leucine-rich repeat protein 2, ISLR2.13124.20.3)",0.27,"[0.19-0.35] unit decrease","Affymetrix [10572788] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(APOA1.assay, whole)",2.529,"[NR] unit decrease","Illumina [335603]","N"]
[36,"rs151113958",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.896,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(Hispanic)",0.188,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs780093-?","rs780093",0,780093,"intron_variant",0,"NR",{"v":7e-14,"d":"7.00E-14"},13.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs7225002",17,44572068,"rs3874943","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","Reaction time","330,069 European ancestry individuals","NA","17q21.31","NSFP1","NSFP1 - RDM1P2","ENSG00000282733","ENSG00000281797",null,7561,9244,"rs3874943-?","rs3874943",0,3874943,"intron_variant",1,"NR",{"v":7e-14,"d":"7.00E-14"},13.1549019599857,null,0.01303,"[0.0096-0.0164] unit increase","Affymetrix [805426] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2017-04-05",27899403,"Jones GT","2016-11-29","Circ Res","www.ncbi.nlm.nih.gov/pubmed/27899403","Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.","Abdominal aortic aneurysm","4,972 European ancestry cases, 99,858 European ancestry controls","2,482 European ancestry cases, 2,750 cases, 2,645 European ancestry controls, 5,263 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.096,{"v":8E-14,"d":"8.00E-14"},13.096910013008,null,1.24,"[1.18-1.32]","Affymetrix, Illumina [5363770] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(APBB2)",0.37522233,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[17,"rs117026536",8,19830921,"rs10096633","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-T","rs10096633",0,10096633,"regulatory_region_variant",1,0.12,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,null,0.169,"[0.12-0.21] unit decrease","Illumina [561583]","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.891,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,"(East Asian)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"19:19510831_AT_A",19,19591066,"rs10401193","2015-09-24",25282103,"Wood AR","2014-10-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25282103","Defining the role of common variation in the genomic and biological architecture of adult human height.","Height","253,288 European ancestry individuals","80,067 European ancestry individuals","19p13.11","GATAD2A","GATAD2A",null,null,"ENSG00000167491",null,null,"rs10401193-A","rs10401193",0,10401193,"intron_variant",0,0.819,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,null,0.028,"[0.02-0.036] unit increase","Affymetrix, Illumina, Perlegen [2550858] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":1E-13,"d":"1.00E-13"},13,"(TG.by.NMR, whole)",0.033,"[NR] unit decrease","Illumina [335603]","N"]
[3,"rs629301",1,109818530,"rs646776","2019-04-30",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Low density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.27,{"v":1E-13,"d":"1.00E-13"},13,"(Indian)",5.26,"[3.87-6.65] unit decrease","Illumina [551825]","N"]
[7,"rs11681659",2,135837906,"rs7570971","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-A","rs7570971",0,7570971,"intron_variant",0,0.35,{"v":1E-13,"d":"1.00E-13"},13,null,0.03,"[NR] unit increase","NR [NR] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.842,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",0.0367,"[0.027-0.046] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1045,{"v":1E-13,"d":"1.00E-13"},13,null,0.0312,"[0.022-0.041] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.707,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44192590,"rs35524223","2017-06-16",28166213,"Wain LV","2017-02-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28166213","Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.","Lung function (FEV1)","48,943 European ancestry individuals.","57,176 European ancestry individuals, 38,199 individuals.","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs35524223-A","rs35524223",0,35524223,"intron_variant",0,0.22,{"v":1E-13,"d":"1.00E-13"},13,null,0.061,"[0.045-0.077] unit decrease","Affymetrix [up to 27624732] (imputed)","N"]
[37,"rs3761077",19,19336608,"rs2238675","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.887,{"v":1E-13,"d":"1.00E-13"},13,"(Hispanic)",0.164,"[0.12-0.21] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1E-13,"d":"1.00E-13"},13,"(KMT2C)",0.38122472,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","LDL cholesterol levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","656 Han Chinese ancestry cases, 933 Han Chinese ancestry controls","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":1E-13,"d":"1.00E-13"},13,null,0.22,"[0.16-0.28] mmol/L decrease","Illumina [4642479] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.748,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(AA)",0.218,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230295691,"rs4846914","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846914-G","rs4846914",0,4846914,"intron_variant",0,0.4,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.07,"[0.05-0.09] unit decrease","Affymetrix [389878]","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Total cholesterol levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4253,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.0656419,"[0.78-1.35] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2017-03-14",27599772,"Ram R","2016-09-07","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/27599772","A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.","Hypertriglyceridemia","927 Saudi Arabian ancestry cases, 3,159 Saudi Arabian ancestry controls","317 Saudi Arabian ancestry cases, 1,098 Saudi Arabian ancestry controls","7q11.23","TBL2, MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.82,"[1.41-2.38]","Affymetrix [~ 8000000] (imputed)","N"]
[17,"rs117026536",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.89,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(East Asian)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alkaline phosphatase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.5,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.4,"[0.50-2.30] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[21,"rs201220977",10,65048306,"rs7080386","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7080386-A","rs7080386",0,7080386,"intron_variant",0,0.416,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(Heparin-binding EGF-like growth factor, HBEGF.14094.29.3)",0.19,"[0.13-0.25] unit increase","Affymetrix [10572788] (imputed)","N"]
[21,"rs7924036",10,65138910,"rs7910927","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7910927-T","rs7910927",0,7910927,"intron_variant",0,0.51,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(Women)",0.046,"[0.034-0.058] umol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[23,"rs2727263",11,61603358,"rs2727271","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Non-albumin protein levels","98,538 Japanese ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs2727271-?","rs2727271",0,2727271,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.03693,"[0.027-0.047] unit increase novel","Illumina [6108953] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.358,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(East Asian)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43567337,"rs1879586","2017-08-03",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Invasive epithelial ovarian cancer","22,406 European ancestry cases, 40,941 European ancestry controls","NA","17q21.31","NR","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs1879586-G","rs1879586",0,1879586,"intron_variant",0,0.181254,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.1339011,"[1.09660984313914-1.1724605092959]","Illumina [11595112] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.041,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs2278426",19,11350488,"rs2278426","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","19p13.2","ANGPTL8","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.03571,"[0.026-0.045] unit decrease novel","Illumina [6108953] (imputed)","N"]
[37,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(HLA-DRB3)",0.37757713,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference adjusted for BMI","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.8425,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(EA)",0.0362,"[0.026-0.046] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.069,"[0.05-0.09] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.917,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Hispanic)",0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.44,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Asian initial, BMI unadjusted)",0.064,"[0.046-0.082] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(EA)",0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15146061,"rs35574015","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","16p13.11","NTAN1","PDXDC1, NTAN1",null,null,"ENSG00000179889, ENSG00000157045",null,null,"rs35574015-C","rs35574015",0,35574015,"intron_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Lysophosphatidylcholine with acyl residue C18:1/Lysophosphatidylcholine with acyl residue C20:3)",0.31705,"[0.23-0.4] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2017-11-01",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","HDL cholesterol levels","2,623 European ancestry type 2 diabetes cases and controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.47,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,2.1,"(% variance) increase","Affymetrix [389878]","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43567337,"rs1879586","2017-08-07",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","High-grade serous ovarian cancer","13,037 European ancestry cases, 40,941 European ancestry controls","NA","17q21.31","NR","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs1879586-G","rs1879586",0,1879586,"intron_variant",0,0.181254,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,1.1585579,"[1.11378456264581-1.20513099189349]","Illumina [11595112] (imputed)","N"]
[37,"rs12985293",19,19663850,"rs892023","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Highest math class taken (MTAG)","811,539 European ancestry individuals","NA","19p13.11","Intergenic","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,6382,8666,"rs892023-A","rs892023",0,892023,"regulatory_region_variant",1,0.6077,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(MTAG)",0.0124,"[0.0091-0.0157] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21428289,"rs71435601","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","2p24.1","NR","AC067959.1 - AC018742.1","ENSG00000271629","ENSG00000233005",null,6521,15758,"rs71435601-G","rs71435601",0,71435601,"intergenic_variant",1,0.133847,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,0.11650893,"[0.085-0.148] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","2p23.3","GCKR, C2orf16","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,3.2,"[2.40-4.0] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[17,"rs117026536",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.889,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(East Asian)",0.154,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.928632,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,2.214072,"[1.79-2.64]","Affymetrix, Illumina [2928658] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(Leucine-rich repeat and transmembrane domain-containing protein 2, LRTM2.8906.60.3)",0.19,"[0.13-0.25] unit increase","Affymetrix [10572788] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.041,"[NR] unit increase","NR [NR] (imputed)","N"]
[17,"rs117026536",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.916,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Hispanic)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.541,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,1.06,"[1.04-1.08]","Affymetrix [9149595] (imputed)","N"]
[29,"rs1077835",15,58723939,"rs2070895","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-A","rs2070895",0,2070895,"intron_variant",0,0.41,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Asian initial, BMI unadjusted)",0.077,"[0.055-0.099] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(HDL-C.by.NMR, fasting)",1.591,"[NR] unit decrease","Illumina [335603]","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.308,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(Hispanic)",0.117,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs2736598",11,61706011,"rs2736600","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FVC)","approximately 372,000 European ancestry individuals","NA","11q12.3",null,"RNU6-1243P - BEST1","ENSG00000200898","ENSG00000167995",null,539,11282,"rs2736600-?","rs2736600",0,2736600,"regulatory_region_variant",1,"NR",{"v":6e-13,"d":"6.00E-13"},12.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[28,"rs139974673",15,44355362,"rs143573049","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","15q15.3",null,"FRMD5",null,null,"ENSG00000171877",null,null,"rs143573049-?","rs143573049",0,143573049,"intron_variant",0,"NR",{"v":6e-13,"d":"6.00E-13"},12.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,43758787,"rs62055701","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs62055701-A","rs62055701",0,62055701,"intron_variant",0,0.214491,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,7.19,"z score increase","NR [~ 10847151] (imputed)","N"]
[34,"rs2074404",17,44865439,"rs2074404","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs2074404-T","rs2074404",0,2074404,"intron_variant",0,"NR",{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,0.012507,"[0.0091-0.0159] unit increase","Affymetrix [18485882] (imputed)","N"]
[18,"rs2954021",8,126486409,"rs17321515","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-A","rs17321515",0,17321515,"intron_variant",0,0.56,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,6.42,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.4184,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,0.02607749,"[0.019-0.033] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,43731719,"rs241036","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Menarche (age at onset)","approximately 242,000 European ancestry individuals","NA","17q21.31",null,"LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs241036-?","rs241036",0,241036,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-13,"d":"7.00E-13"},12.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs35076622",17,43854655,"rs34186148","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs34186148C","rs34186148",0,34186148,"intron_variant",0,"NR",{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,0.01715,"[0.012-0.022] unit increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs16940904",17,44252468,"rs2532263","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2532263-G","rs2532263",0,2532263,"intron_variant",0,0.81,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(EA)",1.0526316,"[1.03-1.08] (Oncoarray)","Illumina [~ 11800000] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(Apolipoprotein L1, APOL1.9506.10.3)",0.18,"[0.12-0.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[15,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.81,{"v":8e-13,"d":"8.00E-13"},12.096910013008,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19836646,"rs78963197","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,11876,99979,"rs78963197-C","rs78963197",0,78963197,"intergenic_variant",1,0.124,{"v":8e-13,"d":"8.00E-13"},12.096910013008,null,0.0905,"[0.066-0.115] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[30,"rs11644601",16,15172118,"rs11644601","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipid measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16p13.11","NPIPA5, PDXC1","RRN3, PDXDC1",null,null,"ENSG00000085721, ENSG00000179889",null,null,"rs11644601-C","rs11644601",0,11644601,"intron_variant",0,0.28,{"v":8e-13,"d":"8.00E-13"},12.096910013008,"(ratio of bis-allylic bonds to double bonds in lipids)",0.1,"[0.08-0.12] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[33,"rs72836561",17,41840849,"rs77697917","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","17q21.31","SOST, DUSP3","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-T","rs77697917",0,77697917,"intergenic_variant",1,0.03,{"v":8e-13,"d":"8.00E-13"},12.096910013008,null,0.163,"[0.12-0.21] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-?","rs12678919",0,12678919,"intergenic_variant",1,0.09,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","HDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.384,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,"(Hispanic)",0.094,"[0.069-0.119] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2017-02-15",27587472,"Postmus I","2016-09-01","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/27587472","Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.","Response to statins (HDL cholesterol change)","16,769 European ancestry individuals","10,951 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.326,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,0.0071,"[0.0090-0.0130] unit increase","Affymetrix, Illumina, Perlegen [up to 2500000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-T","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,1.45,"[1.06-1.84] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[37,"rs58542926",19,19610596,"rs3794991","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19p13.11","GATAD2A, CILP2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs3794991-T","rs3794991",0,3794991,"intron_variant",0,0.0775,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,"(EA)",0.1299,"[0.094-0.166] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-?","rs5167",0,5167,"missense_variant",0,"NR",{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,0.03734,"[0.027-0.048] unit decrease novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,"(male)",0.25305,"[0.18-0.32] unit increase","Affymetrix [7794483] (imputed)","N"]
[15,"rs33951980",7,72856269,"rs2240466","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2240466-G","rs2240466",0,2240466,"3_prime_UTR_variant",0,0.87,{"v":1e-12,"d":"1.00E-12"},12,null,0.14,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[15,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.809,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19847690,"rs10503669","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-?","rs10503669",0,10503669,"intergenic_variant",1,null,{"v":1e-12,"d":"1.00E-12"},12,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[23,"rs174468",11,61663691,"rs174468","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","RAB3IL1","FADS3 - RAB3IL1","ENSG00000221968","ENSG00000167994",null,4168,1082,"rs174468-A","rs174468",0,174468,"regulatory_region_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.01,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[28,"rs139974673",15,43726625,"rs150844304","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","15q15.3",null,"TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-?","rs150844304",0,150844304,"intron_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.45,{"v":1e-12,"d":"1.00E-12"},12,null,2.88,"[2.14-3.62] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.745,{"v":1e-12,"d":"1.00E-12"},12,"(AA)",0.183,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43569909,"rs146746174","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Cognitive performance","257,841 European ancestry individuals","NA","17q21.31","Intergenic","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,1794,14198,"rs146746174-T","rs146746174",1,62065449,"intergenic_variant",1,0.815,{"v":1e-12,"d":"1.00E-12"},12,null,0.0263,"[0.019-0.034] unit increase","Affymetrix, Illumina [10100000] (imputed)","N"]
[34,"rs16940904",17,43719143,"rs393152","2016-07-08",26077951,"Kouri N","2015-06-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26077951","Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.","Corticobasal degeneration","152 cases, 3,111 controls","67 cases, 457 controls","17q21.31","MAPT","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs393152-?","rs393152",0,393152,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,3.7,"[NR]","Illumina [533898] (imputed)","N"]
[34,"rs7225002",17,44572068,"rs3874943","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hair color","approximately 452,000 European ancestry individuals","NA","17q21.31",null,"NSFP1 - RDM1P2","ENSG00000282733","ENSG00000281797",null,7561,9244,"rs3874943-?","rs3874943",0,3874943,"intron_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs80204526",18,47106028,"rs149615216","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-T","rs149615216",0,149615216,"intron_variant",0,0.01,{"v":1e-12,"d":"1.00E-12"},12,null,0.229,"[0.17-0.29] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity (ABCA-1 dependent assay)","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","19q13.32","APOE/C1/C2/C4","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-G","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.886,{"v":1e-12,"d":"1.00E-12"},12,null,0.2155,"[0.16-0.27] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.989,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Hispanic)",0.507,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","LDL cholesterol","4,763 Northern Finnish founder individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.21,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.16,"[0.11-0.20] mmol/l decrease","Illumina [329091]","N"]
[6,"rs780110",2,27715416,"rs2303369","2012-02-10",22267201,"Stolk L","2012-01-22","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22267201","Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.","Menopause (age at onset)","38,968 European ancestry female individuals","Up to 14,435 European ancestry female individuals","2p23.3","FNDC4","FNDC4",null,null,"ENSG00000115226",null,null,"rs2303369-T","rs2303369",0,2303369,"intron_variant",0,0.388,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.175,"[0.13-0.22] years decrease","Affymetrix, Illumina [2551160] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-12-01",26831199,"Pattaro C","2016-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26831199","Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.","Glomerular filtration rate in non diabetics (creatinine)","118,448 European ancestry individuals","36,433 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.0065,"[0.0047-0.0083] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte counts","171,643 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6052,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.02574395,"[0.019-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[15,"rs62466318",7,72856430,"rs1178979","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","7q11.23","TBL2, MLXIPL, BAZ1B, BCL7B","BAZ1B",null,null,"ENSG00000009954",null,null,"rs1178979-A","rs1178979",0,1178979,"3_prime_UTR_variant",0,0.8,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.05,"[0.03-0.07] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.84,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,8.21,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.596,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Hispanic)",0.099,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs201220977",10,65104500,"rs7896518","2012-04-03",22423221,"Qayyum R","2012-03-08","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22423221","A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.","Mean platelet volume","16,388 African American individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-A","rs7896518",0,7896518,"intron_variant",0,0.324,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Platelet Count)",5.18,"[3.73-6.63] 10^9 L increase","Affymetrix, Illumina [~ 2200000] (imputed)","N"]
[23,"rs7943992",11,61272565,"rs7125196","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","11q12.2","LOC105369329, MIR4488","AP003108.1 - MIR4488","ENSG00000255931","ENSG00000266006",null,5017,3503,"rs7125196-T","rs7125196",0,7125196,"intergenic_variant",1,0.77,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Asian, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[27,"rs78689694",11,126244955,"rs4307732","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs4307732-G","rs4307732",0,4307732,"non_coding_transcript_exon_variant",0,0.901,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(EA)",0.059,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.795,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(East Asian)",0.117,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.49,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(East Asian)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs3867518",16,15378697,"rs1629212","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","16p13.11","MPV17L, PDXDC1, PLA2G10","AC126763.1 - AC137803.1","ENSG00000257391","ENSG00000277770",null,127820,74138,"rs1629212-A","rs1629212",0,1629212,"intergenic_variant",1,0.5974,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(lysoPhosphatidylcholine acyl C20:3)",0.0493,"[0.036-0.063] unit decrease","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2015-11-07",25629512,"Cheng CY","2015-01-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25629512","New loci and coding variants confer risk for age-related macular degeneration in East Asians.","Exudative age-related macular degeneration","2,119 East Asian ancestry cases, 5,691 East Asian ancestry controls","4,226 East Asian ancestry cases, 10,289 East Asian ancestry controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-?","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,1.41,null,"Illumina [4471719] (imputed)","N"]
[34,"rs16940904",17,44037491,"rs17650842","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17650842-A","rs17650842",0,17650842,"intron_variant",0,0.21663,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,7.01,"z score decrease","NR [~ 10847151] (imputed)","N"]
[35,"rs9304381",18,47181668,"rs2156552","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-T","rs2156552",0,2156552,"intergenic_variant",1,0.81,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.03,"[0.02-0.04] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.493,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs272863",5,131714409,"rs274567","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274567-T","rs274567",0,274567,"non_coding_transcript_exon_variant",0,0.37,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(acetylcarnitine)",0.018,"[0.012-0.024] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[21,"rs201220977",10,65027610,"rs10761731","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,0.43,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,2.38,"[1.64-3.12] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[27,"rs78689694",11,126244955,"rs4307732","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","11q24.2","ST3GAL4","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs4307732-A","rs4307732",0,4307732,"non_coding_transcript_exon_variant",0,0.11,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.067,"[0.047-0.087] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.33,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(HDL)",0.104,"[0.075-0.133] mmol/l increase","Illumina [NR] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.29,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(1-palmitoylglycerophosphoethanolamine)",0.019,"[0.013-0.025] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2009-05-05",19359809,"Hiura Y","2009-04-10","Circ J","www.ncbi.nlm.nih.gov/pubmed/19359809","Identification of genetic markers associated with high-density lipoprotein-cholesterol by genome-wide screening in a Japanese population: the Suita study.","HDL cholesterol","900 Japanese ancestry individuals","1,810 Japanese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.2,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,6.2,"mg/dl increase","Illumina [368274]","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43567337,"rs1879586","2017-08-07",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Serous invasive ovarian cancer","14,049 European ancestry cases, 40,941 European ancestry controls","NA","17q21.31","NR","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs1879586-G","rs1879586",0,1879586,"intron_variant",0,0.181254,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,1.1472089,"[1.10406141518038-1.19204274035159]","Illumina [11595112] (imputed)","N"]
[34,"rs16940904",17,44326864,"rs2696625","2019-01-18",30531941,"Doherty A","2018-12-10","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30531941","GWAS identifies 14 loci for device-measured physical activity and sleep duration.","Physical activity (overall physical activity time)","91,105 European ancestry individuals","NA","17q21.31","KANSL1-AS1","MAPK8IP1P1 - AC005829.2","ENSG00000281283","ENSG00000262539",null,4454,10053,"rs2696625-A","rs2696625",0,2696625,"intergenic_variant",1,0.77,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.037,"[0.027-0.047] SD units decrease","NR [9926106] (imputed)","N"]
[2,"rs638714",1,63118196,"rs10889353","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.32,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.08,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[15,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,73056750,"rs6957745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Monocyte percentage of white cells","170,494 European ancestry individuals","NA","7q11.23","intergenic","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,17877,25405,"rs6957745-C","rs6957745",0,6957745,"intergenic_variant",1,0.2032,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0308444,"[0.022-0.04] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[20,"10:22255616_CT_C",10,21849769,"rs11012737","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","10p12.31","MLLT10","MLLT10",null,null,"ENSG00000078403",null,null,"rs11012737-?","rs11012737",0,11012737,"intron_variant",0,null,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,1.07,"[1.05-1.10]","Affymetrix, Illumina [43000000] (imputed)","N"]
[21,"rs7924036",10,64955581,"rs10761723","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Prothrombin time","58,110 Japanese ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761723-?","rs10761723",0,10761723,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0405,"[0.029-0.052] unit increase novel","Illumina [6108953] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.686,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.1466,"[0.11-0.19] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[34,"rs2435200",17,44078982,"rs2435201","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs2435201-A","rs2435201",0,2435201,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,6.944,"z score decrease","Affymetrix [10847151] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-01-11",30054458,"Xue A","2018-07-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30054458","Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.","Type 2 diabetes","61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls","NA","19p13.11","SUGP1","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.0765857554285534,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0921,"[0.066-0.118] unit increase","NR [5035015] (imputed)","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.183,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,"(Hispanic)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43991272,"rs17563986","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability (MTAG)","436,124 European ancestry individuals","NA","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17563986-?","rs17563986",0,17563986,"intron_variant",0,"NR",{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,6.905,"z score increase","Affymetrix, Illumina, Perlegen [7333576] (imputed)","N"]
[34,"rs16940904",17,44038785,"rs62063281","2019-02-08",30664745,"Tachmazidou I","2019-01-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30664745","Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.","Osteoarthritis (hip)","15,704 European ancestry cases, 378,169 European ancestry controls","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62063281-G","rs62063281",0,62063281,"intron_variant",0,0.22,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,1.1,"[1.07-1.13]","Affymetrix, Illumina [up to 17000000] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.0755,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,1.07,"[1.05-1.10]","Affymetrix, Illumina [247470]","N"]
[6,"rs1260326",2,27741237,"rs780094","2015-09-24",25282103,"Wood AR","2014-10-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25282103","Defining the role of common variation in the genomic and biological architecture of adult human height.","Height","253,288 European ancestry individuals","80,067 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.386,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,null,0.021,"[0.015-0.027] unit decrease","Affymetrix, Illumina, Perlegen [2550858] (imputed)","N"]
[17,"rs117026536",8,19849757,"rs17091905","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,24987,86868,"rs17091905-A","rs17091905",0,17091905,"intergenic_variant",1,0.124,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(HDL)",0.15,"[0.11-0.19] mmol/l increase","Illumina [NR] (imputed)","N"]
[21,"rs7924036",10,65191645,"rs7924036","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","10q21.3",null,"JMJD1C",null,null,"ENSG00000171988",null,null,"rs7924036-?","rs7924036",0,7924036,"intron_variant",0,"NR",{"v":6e-12,"d":"6.00E-12"},11.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs490098",15,58694020,"rs16940212","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","15q21.3","Intergenic","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940212-?","rs16940212",0,16940212,"intron_variant",0,null,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[35,"rs9304381",18,47181668,"rs2156552","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-T","rs2156552",0,2156552,"intergenic_variant",1,0.84,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,null,1.2,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[37,"rs11882123",19,19545696,"rs2965183","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","19p13.11","GATAD2A, MIR640","GATAD2A",null,null,"ENSG00000167491",null,null,"rs2965183-A","rs2965183",0,2965183,"intron_variant",0,0.35,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(EA)",1.04,"[1.02-1.06] (Oncoarray)","Illumina [~ 11800000] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2018-11-19",30220432,"Haas ME","2018-09-06","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30220432","Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.","Urinary albumin excretion","382,500 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-T","rs4665972",0,4665972,"intron_variant",0,0.393,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,0.01176,"[0.0084-0.0151] unit increase","Affymetrix [11709857] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-A","rs2126259",0,2126259,"intron_variant",0,0.13,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,0.02,"[0.01-0.03] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[18,"rs2954021",8,126479315,"rs6982636","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982636-?","rs6982636",0,6982636,"intron_variant",0,"NR",{"v":7e-12,"d":"7.00E-12"},11.1549019599857,"(APOB.assay, whole)",1.95,"[NR] unit decrease","Illumina [335603]","N"]
[34,"rs16940904",17,44081064,"rs8070723","2011-01-03",21044948,"Spencer CC","2010-11-02","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21044948","Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.","Parkinson's disease","1,705 European ancestry cases, 5,175 European ancestry controls","1,039 European ancestry cases, 1,984 European ancestry controls","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs8070723-?","rs8070723",0,8070723,"intron_variant",0,0.76,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,1.3,"[1.19-1.43]","Illumina [532616]","N"]
[37,"rs11882123",19,19484295,"rs2905432","2018-12-17",29483656,"Pardinas AF","2018-02-26","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29483656","Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.","Schizophrenia","40,675 European ancestry cases, 64,643 European ancestry controls","1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls","19p13.11","CILP2, GATAD2A, HAPLN4, MAU2, NCAN, NDUFA13, PBX4, SUGP1, TM6SF2, TSSK6, YJEFN3","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,14731,12340,"rs2905432-?","rs2905432",0,2905432,"intergenic_variant",1,"NR",{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,1.071,"[1.05-1.09]","Illumina [8000000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2009-03-01",19198609,"Kathiresan S","2009-02-08","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19198609","Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.","Myocardial infarction (early onset)","2,967 European ancestry cases, 3,075 European ancestry controls","9,746 European ancestry cases, 9,746 European ancestry controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.81,{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,1.19,"[1.13-1.26]","Affymetrix [~ 2500000] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.597,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(Hispanic)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs7935835",11,61796396,"rs11230876","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","11q12.3",null,"AP003733.1 - AP003733.2","ENSG00000244176","ENSG00000254424",null,16322,43958,"rs11230876-?","rs11230876",0,11230876,"intergenic_variant",1,"NR",{"v":8e-12,"d":"8.00E-12"},11.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[24,"rs2229738",11,68562328,"rs17610395","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","11q13.3","CPT1A","CPT1A",null,null,"ENSG00000110090",null,null,"rs17610395-?","rs17610395",1,2229738,"missense_variant",0,"NR",{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(LA/PUFA)",0.17,"[0.13-0.21] unit increase","Illumina [~ 7700000] (imputed)","N"]
[29,"rs1077835",15,58730498,"rs588136","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","15q21.3","LIPC","LIPC-AS1, ALDH1A2, LIPC",null,null,"ENSG00000259293, ENSG00000128918, ENSG00000166035",null,null,"rs588136-T","rs588136",0,588136,"intron_variant",0,0.8,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(1-stearoylglycerophosphoethanolamine)",0.029,"[0.021-0.037] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[34,"rs16940904",17,43844560,"rs55657917","2019-01-18",30531941,"Doherty A","2018-12-10","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30531941","GWAS identifies 14 loci for device-measured physical activity and sleep duration.","Physical activity (overall physical activity time)","91,105 European ancestry individuals","NA","17q21.31","LINC02210-CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs55657917-T","rs55657917",0,55657917,"intron_variant",0,0.779584,{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,0.036815435,"[0.026-0.047] SD units decrease","NR [9926106] (imputed)","N"]
[21,"rs7924036",10,64927823,"rs1935","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs1935-?","rs1935",0,1935,"missense_variant",0,null,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,1.07,"[1.05-1.09]","Affymetrix, Illumina [43000000] (imputed)","N"]
[21,"rs7924036",10,65301725,"rs7897379","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs7897379-C","rs7897379",0,7897379,"intron_variant",0,0.48,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,"(Lysosomal protective protein, CTSA.3179.51.2)",0.17,"[0.11-0.23] unit increase","Affymetrix [10572788] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p32.3",null,"PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.45,{"v":1e-11,"d":"1.00E-11"},11,null,0.101,"[0.072-0.13] unit decrease","Illumina [561583]","N"]
[11,"rs59136961",6,34618893,"rs2814993","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6p21.31","C6orf106","C6orf106",null,null,"ENSG00000196821",null,null,"rs2814993-A","rs2814993",0,2814993,"intron_variant",0,0.1431,{"v":1e-11,"d":"1.00E-11"},11,null,0.061,"[0.044-0.078] unit increase","NR [8041861] (imputed)","N"]
[15,"rs62466318",7,72857049,"rs1178977","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs1178977-A","rs1178977",0,1178977,"splice_region_variant",0,0.89,{"v":1e-11,"d":"1.00E-11"},11,"(BMI unadjusted)",0.122,"[0.087-0.157] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-A","rs112875651",0,112875651,"intron_variant",0,0.3925,{"v":1e-11,"d":"1.00E-11"},11,null,0.02517532,"[0.018-0.032] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[21,"rs201220977",10,65027610,"rs10761731","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Vascular endothelial growth factor levels","7,118 Finnish ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,null,{"v":1e-11,"d":"1.00E-11"},11,null,0.1187,"[0.085-0.153] SD units increase","NR [10700000] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.32,{"v":1e-11,"d":"1.00E-11"},11,"(X-11550)",0.01,"[0.008-0.012] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.5,{"v":1e-11,"d":"1.00E-11"},11,"(X-12038)",0.013,"[0.0091-0.0169] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs112259268","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","17q21.31","intergenic","CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs112259268-A","rs112259268",0,112259268,"intergenic_variant",1,0.0275,{"v":1e-11,"d":"1.00E-11"},11,null,0.0632,"[0.045-0.081] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[34,"rs71279459",17,43777313,"rs1724422","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs1724422G","rs1724422",0,1724422,"intron_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.01616,"[0.012-0.021] unit increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs2435200",17,44065263,"rs713522","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs713522-T","rs713522",0,713522,"intron_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,6.804,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.869,{"v":1e-11,"d":"1.00E-11"},11,"(AA)",0.255,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45426792,"rs141622900","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity (BHK stimulated assay)","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","19q13.32","APOE/C1/C2/C4","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,4186,3269,"rs141622900-G","rs141622900",0,141622900,"intergenic_variant",1,0.942,{"v":1e-11,"d":"1.00E-11"},11,null,0.2833,"[0.20-0.37] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.67,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.043,"[0.031-0.055] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA, Catalase)",0.3359,"[0.24-0.43] unit decrease","Affymetrix [509946]","N"]
[5,"rs562338",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.196,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(Hispanic)",0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs59136961",6,34552797,"rs2814944","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","6p21.31","C6orf106","AL031577.1 - C6orf106","ENSG00000196114","ENSG00000196821",null,8364,2268,"rs2814944-A","rs2814944",0,2814944,"intergenic_variant",1,0.1554,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.0479,"[0.034-0.062] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[15,"rs62466318",7,73017005,"rs13226650","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13226650-A","rs13226650",0,13226650,"intron_variant",0,0.83,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(TG)",0.12,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.46,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.57,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(BMI-adjusted)",0.026,"[0.018-0.034] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[29,"rs1077835",15,58723939,"rs2070895","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA)",1.1494253,null,"Illumina [12023830] (imputed)","N"]
[30,"rs3198697",16,15129940,"rs3198697","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-C","rs3198697",0,3198697,"missense_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.027,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41926126,"rs72836561","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","17q21.31","CD300LG","CD300LG",null,null,"ENSG00000161649",null,null,"rs72836561-T","rs72836561",0,72836561,"missense_variant",0,0.0294,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.23653477,"[0.17-0.31] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[34,"rs546735951",17,43488792,"rs62064641","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","17q21.31","NR","ARHGAP27, ARHGAP27, ARHGAP27",null,null,"ENSG00000276836, ENSG00000276907, ENSG00000159314",null,null,"rs62064641-C","rs62064641",0,62064641,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.02055,"[0.015-0.027] unit increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs16940904",17,44787312,"rs1378358","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling miserable","376,097 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs1378358-T","rs1378358",0,1378358,"intron_variant",0,0.206287,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,6.69,"z score increase","NR [10847151] (imputed)","N"]
[34,"rs16940904",17,44826056,"rs9896243","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs9896243-G","rs9896243",0,9896243,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.01934,"[0.014-0.025] unit increase","Affymetrix [10847151] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(APOA1.assay, fasting)",2.616,"[NR] unit decrease","Illumina [335603]","N"]
[37,"rs58542926",19,19407718,"rs10401969","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-?","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[37,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.01434,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Systolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0833,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.3255,"[0.23-0.42] mmHg decrease","Affymetrix [NR] (imputed)","N"]
[10,"rs272863",5,131660431,"rs273914","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs273914-A","rs273914",0,273914,"intron_variant",0,0.37,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(oleoylcarnitine)",0.023,"[0.015-0.031] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[15,"rs138574868",7,73035857,"rs7800944","2015-07-07",25288136,"Cornelis MC","2014-10-07","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25288136","Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.","Coffee consumption (cups per day)","91,462 European ancestry individuals","30,062 European ancestry individuals, 7,964 African American individuals","7q11.23","MLXIPL, TBL2, VPS37D","MLXIPL",null,null,"ENSG00000009950",null,null,"rs7800944-T","rs7800944",0,7800944,"intron_variant",0,0.72,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.05,"[0.030-0.070] unit decrease","Affymetrix, Illumina [2373958] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.875,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(East Asian)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.614,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(Hispanic)",0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2018-11-19",30220432,"Haas ME","2018-09-06","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30220432","Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.","Urinary albumin excretion","382,500 European ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.579,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.01136,"[0.008-0.0147] unit increase","Affymetrix [11709857] (imputed)","N"]
[21,"rs201220977",10,65027610,"rs10761731","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of white cells","171,542 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,0.4177,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.02406048,"[0.017-0.031] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[23,"rs2924438",11,61313525,"rs77128898","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Cognitive performance (MTAG)","402,382 European ancestry individuals","NA","11q12.2","Intergenic","SYT7",null,null,"ENSG00000011347",null,null,"rs77128898-T","rs77128898",0,77128898,"missense_variant",0,0.0358,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(MTAG)",0.041,"[0.029-0.053] unit decrease","Affymetrix, Illumina [7100000] (imputed)","N"]
[23,"rs2727263",11,61603358,"rs2727271","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q12.2","FADS1","FADS2",null,null,"ENSG00000134824",null,null,"rs2727271-A","rs2727271",0,2727271,"intron_variant",0,0.89,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(X-12990--docosapentaenoic acid (n6-DPA))",0.055,"[0.039-0.071] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[29,"rs723967",15,58688467,"rs920915","2013-07-31",23455636,"Fritsche LG","2013-03-03","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23455636","Seven new loci associated with age-related macular degeneration.","Age-related macular degeneration","6,713 European ancestry cases, 48,402 European ancestry contols, 110 Southern Indian ancestry cases, 119 Southern Indian ancestry controls, 827 Japanese ancestry cases, 3,323 Japanese ancestry controls","9,070 European ancestry cases, 7,683 European ancestry contols, 461 East Asian ancestry cases, 547 East Asian ancestry controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs920915-C","rs920915",0,920915,"intron_variant",0,0.48,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,1.13,"[1.09-1.17]","Affymetrix, Illumina [2442884] (imputed)","N"]
[30,"rs72789541",16,15130594,"rs6498540","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs6498540-A","rs6498540",0,6498540,"3_prime_UTR_variant",0,0.7,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(dihomo-linolenate (20:3n3 or n6))",0.017,"[0.011-0.023] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[34,"rs16940904",17,43778680,"rs17688916","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling worry","372,869 European ancestry individuals","NA","17q21.31","SPATA32","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs17688916-A","rs17688916",0,17688916,"intron_variant",0,0.196725,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,6.653,"unit increase","NR [10847151] (imputed)","N"]
[34,"rs16940904",17,44351387,"rs2732708","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling miserable","376,097 European ancestry individuals","NA","17q21.31","NR","AC005829.1 - ARL17B","ENSG00000261575","ENSG00000228696",null,5327,763,"rs2732708-T","rs2732708",0,2732708,"intergenic_variant",1,0.214039,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,6.64,"z score increase","NR [10847151] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2011-11-16",22003152,"Grallert H","2011-10-14","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/22003152","Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.","Lipoprotein-associated phospholipase A2 activity and mass","12,126 European ancestry individuals, 1,538 individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(Activity concentrations)",0.045,"[0.031-0.059] unit decrease","Affymetrix, Illumina [2661766] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.756,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(AA)",0.196,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136707982,"rs6754311","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","2q21.3","DARS","DARS",null,null,"ENSG00000115866",null,null,"rs6754311-T","rs6754311",0,6754311,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.0390103,"[0.027-0.051] unit increase","Illumina [13520550] (imputed)","N"]
[15,"rs33951980",7,73042443,"rs6460047","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3570,39712,"rs6460047-C","rs6460047",0,6460047,"intergenic_variant",1,0.208,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.0108214,"[0.0076-0.014] unit increase","NR [~ 9732723] (imputed)","N"]
[17,"rs117026536",8,19928582,"rs9644568","2013-08-01",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","Hypertriglyceridemia","1,122 Mexican ancestry cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry cases, 1,054 Mexican ancestry controls","8p21.3","SLC18A1, INTS10, LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103812,8043,"rs9644568-?","rs9644568",0,9644568,"intergenic_variant",1,0.93,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,2,"[1.80-2.20]","Illumina [1361436] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.39,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(Indian)",1.51,"[1.06-1.96] unit decrease","Illumina [551825]","N"]
[34,"rs71279459",17,43781747,"rs1724425","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","RP11-105N13.4","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs1724425-C","rs1724425",0,1724425,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.011456,"[0.0081-0.0149] unit increase","Affymetrix [18485882] (imputed)","N"]
[37,"rs58542926",19,19662220,"rs17216525","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","19p13.11","NCAN, CILP2, PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,4752,10296,"rs17216525-T","rs17216525",0,17216525,"regulatory_region_variant",1,0.07,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.11,"[0.05-0.17] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2012-12-21",23031429,"Surakka I","2012-10-03","Twin Res Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23031429","A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.","Apolipoprotein Levels","1,720 European ancestry monozygotic twins","NA","19q13.32","APOE/APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-G","rs445925",0,445925,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(APOE)",0.229,"[0.16-0.30] unit decrease","Illumina [~ 2500000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.334,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(AA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2012-10-19",21102463,"Franke A","2010-11-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21102463","Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.","Crohn's disease","6,333 European ancestry cases, 15,056 European ancestry controls","15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.418,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,1.15,"[1.10-1.21]","Affymetrix, Illumina [953241] (imputed)","N"]
[25,"rs673335",11,75455021,"rs499974","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q13.5","MOGAT2, DGAT2","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1550,14479,"rs499974-A","rs499974",0,499974,"regulatory_region_variant",1,0.175,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(Trans-ethnic initial)",0.0263,"[0.018-0.035] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2014-03-22",24023261,"Keller M","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023261","THOC5: a novel gene involved in HDL-cholesterol metabolism.","Lipid traits","839 European ancestry individuals","up to 5,248 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.42,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(HDL-C)",6.57,"unit decrease","Affymetrix [390619]","N"]
[34,"rs16940904",17,43991515,"rs192818565","2017-02-25",27225129,"Okbay A","2016-05-26","Nature","www.ncbi.nlm.nih.gov/pubmed/27225129","Genome-wide association study identifies 74 loci associated with educational attainment.","Educational attainment (college completion)","280,007 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs192818565-T","rs192818565",1,62056842,"intron_variant",0,0.8097,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,1.0534867,"[NR]","Affymetrix, Illumina, Perlegen [~ 9300000] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.825,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(AA)",0.215,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(LRP1B)",0.32986814,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.336,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(AA)",0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs72836561",17,41874745,"rs112259268","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","17q21.31",null,"CFAP97D1 - MPP3","ENSG00000231256","ENSG00000161647",null,9765,3422,"rs112259268-?","rs112259268",0,112259268,"intergenic_variant",1,"NR",{"v":6E-11,"d":"6.00E-11"},10.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,43830938,"rs17426174","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","17q21.31","RP11-105N13.4","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs17426174-C","rs17426174",0,17426174,"intron_variant",0,"NR",{"v":6E-11,"d":"6.00E-11"},10.2218487496163,null,0.023148796,"[0.016-0.03] unit decrease","Affymetrix [NR]","N"]
[34,"rs16940904",17,44142332,"rs193236081","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Neuroticism","170,911 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs193236081-T","rs193236081",1,77184207,"intron_variant",0,0.774,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,null,0.028413428,"[0.02-0.037] unit decrease","Affymetrix [up to 6544775] (imputed)","N"]
[36,"rs151113958",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.833,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(AA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs77200710",2,27840640,"rs4666002","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","2p23.3","GCKR","ZNF512, AC074091.1",null,null,"ENSG00000243943, ENSG00000259080",null,null,"rs4666002-?","rs4666002",0,4666002,"intron_variant",0,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(levels)",0,"[1.10-0.70] % increase","Illumina [NR] (imputed)","N"]
[10,"5:131664516_TTATATA_T",5,131652529,"rs11950562","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs11950562-A","rs11950562",0,11950562,"intron_variant",0,0.53,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(homostachydrine)",0.03,"[0.020-0.040] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[21,"rs7924036",10,64934548,"rs10822145","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10822145-C","rs10822145",0,10822145,"intron_variant",0,0.5,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,0.038,"[0.026-0.05] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[29,"rs28690720",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs7228085",18,47160814,"rs7228085","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35262,15906,"rs7228085-?","rs7228085",0,7228085,"intergenic_variant",1,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(XL-HDL-TG)",0.11,"[0.071-0.149] unit increase","Illumina [~ 7700000] (imputed)","N"]
[37,"rs12985293",19,19663850,"rs892023","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (MTAG)","1,311,438 European ancestry individuals","NA","19p13.11","Intergenic","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,6382,8666,"rs892023-A","rs892023",0,892023,"regulatory_region_variant",1,0.6038,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(MTAG)",0.0087,"[0.0062-0.0112] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[15,"rs33951980",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,44027885,"rs139974673","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","15q15.3","CATSPER2P1","CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs139974673-C","rs139974673",0,139974673,"intron_variant",0,0.0261,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.07306267,"[0.051-0.095] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":8e-11,"d":"8.00E-11"},10.096910013008,"(EA)",0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.989,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,"(Hispanic)",0.464,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.748,{"v":1E-10,"d":"1.00E-10"},10,"(AA)",0.19,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-04",29769521,"Ramirez J","2018-05-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29769521","Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.","Resting heart rate","67,062 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.397939,{"v":1E-10,"d":"1.00E-10"},10,null,0.422407,"[0.29-0.55] unit increase","Affymetrix [~ 7800000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-10-16",29743933,"Wu B","2018-03-18","Comput Math Methods Med","www.ncbi.nlm.nih.gov/pubmed/29743933","Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits.","Glycemic traits (multi-trait analysis)","5,947 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,{"$nulls":3},"NR [~ 2500000] (imputed)","N"]
[11,"rs59136961",6,34763982,"rs9469890","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469890-T","rs9469890",0,9469890,"intron_variant",0,0.142,{"v":1E-10,"d":"1.00E-10"},10,null,0.054,"[0.038-0.07] unit increase","Affymetrix [7947838] (imputed)","N"]
[15,"rs33951980",7,73042443,"rs6460047","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3570,39712,"rs6460047-C","rs6460047",0,6460047,"intergenic_variant",1,0.208,{"v":1E-10,"d":"1.00E-10"},10,null,0.011623538,"[0.0081-0.0151] unit increase","NR [~ 10000000] (imputed)","N"]
[18,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,0.758,{"v":1E-10,"d":"1.00E-10"},10,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,64988931,"rs7916868","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7916868-?","rs7916868",0,7916868,"intron_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.0329,"[0.023-0.043] unit decrease novel","Illumina [6108953] (imputed)","N"]
[23,"rs762923346",11,61398595,"rs11230757","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","11q12.2",null,"RPLP0P2",null,null,"ENSG00000243742",null,null,"rs11230757-?","rs11230757",0,11230757,"intron_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":1E-10,"d":"1.00E-10"},10,"(EA)",0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs9303521",17,43805194,"rs9303521","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs9303521-T","rs9303521",0,9303521,"intron_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,6.437,"z score increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs112557952",17,43902541,"rs4327090","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Highest math class taken","430,445 European ancestry individuals","NA","17q21.31","Intergenic","CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000278232, ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000263715, ENSG00000282456",null,null,"rs4327090-A","rs4327090",0,4327090,"intron_variant",0,0.8074,{"v":1E-10,"d":"1.00E-10"},10,null,0.0186,"[0.013-0.024] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[34,"rs2732699",17,44354904,"rs2732699","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2732699-C","rs2732699",0,2732699,"intron_variant",0,0.8401,{"v":1E-10,"d":"1.00E-10"},10,"(EA)",0.0595,"[0.041-0.078] unit increase","Illumina [~ 11800000] (imputed)","N"]
[37,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":1E-10,"d":"1.00E-10"},10,null,0.01472,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.7,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,7.12,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[2,"rs638714",1,63107526,"rs995000","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.18,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(BMI unadjusted)",0.085,"[0.06-0.11] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.21541,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.014155,"[0.0098-0.0185] unit increase","NR [13737936] (imputed)","N"]
[4,"rs11122450",1,230293530,"rs4631704","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4631704-T","rs4631704",0,4631704,"intron_variant",0,0.6104,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.02382391,"[0.016-0.031] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[7,"rs11681659",2,136381348,"rs12465802","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","2q21.3","R3HDM1","R3HDM1",null,null,"ENSG00000048991",null,null,"rs12465802-G","rs12465802",0,12465802,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0368262,"[0.026-0.048] unit increase","Illumina [13520550] (imputed)","N"]
[9,"rs9884390",4,69349018,"rs1117816","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4q13.2","TMPRSS11E","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs1117816-A","rs1117816",0,1117816,"intron_variant",0,0.78,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0212,"[0.015-0.028] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[15,"rs33951980",7,73020337,"rs3812316","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs3812316-C","rs3812316",0,3812316,"missense_variant",0,0.8812,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0213,"[0.015-0.028] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[15,"rs62466318",7,73037366,"rs55747707","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","7q11.23",null,"MLXIPL",null,null,"ENSG00000009950",null,null,"rs55747707-?","rs55747707",0,55747707,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[16,"rs9987289",8,9178268,"rs6984305","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alkaline phosphatase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6984305-A","rs6984305",0,6984305,"intron_variant",0,0.11,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,2.7,"[1.10-4.40] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin (BMI interaction)","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0937,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.001989,"[0.0001-0.00388] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,0.096,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9187242,"rs1461729","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","8p23.1",null,"AC022784.1",null,null,"ENSG00000248538",null,null,"rs1461729-?","rs1461729",0,1461729,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[23,"rs198435",11,61458595,"rs11827215","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","DAGLA",null,null,"ENSG00000134780",null,null,"rs11827215-G","rs11827215",0,11827215,"intron_variant",0,0.7873,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0394,"[0.027-0.052] unit increase","Illumina [up to 1980188] (imputed)","N"]
[28,"rs139974673",15,44027885,"rs139974673","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","15q15.3",null,"CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs139974673-?","rs139974673",0,139974673,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.028,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.369,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(Hispanic)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15130351,"rs1741","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","8,631 European ancestry individuals","NA","16p13.11","PDXDC1, NTAN1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs1741-C","rs1741",0,1741,"3_prime_UTR_variant",0,0.308,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.2,"[NR] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.685,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.683,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.632,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(AA)",0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs2074404",17,44836302,"rs9912530","2018-10-17",29785010,"Khawaja AP","2018-05-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29785010","Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma.","Intraocular pressure","139,555 European ancestry individuals","NA","17q21.31","WNT3","NSF - WNT3","ENSG00000073969","ENSG00000277641",null,1472,3570,"rs9912530-T","rs9912530",0,9912530,"regulatory_region_variant",1,0.272,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.091,"[0.064-0.118] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[34,"rs2074404",17,44865439,"rs2074404","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs2074404-T","rs2074404",0,2074404,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,6.362,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[37,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.051,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19379549,"rs58542926","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.079,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.09,"[1.06-1.12]","Affymetrix, Illumina [247470]","N"]
[1,"rs11591147",1,55505647,"rs11591147","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.984,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,1.25,"[1.16-1.34]","Affymetrix [9149595] (imputed)","N"]
[2,"rs638714",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(VLDL.medium, fasting)",1.32,"[NR] unit decrease","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2010-02-08",20081857,"Saxena R","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081857","Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.","Two-hour glucose challenge","15,234 individuals","up to 30,620 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.07,"[0.05-0.09] mmol/L increase","Affymetrix, Illumina [NR]","N"]
[6,"rs1260326",2,27741237,"rs780094","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin (BMI interaction)","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.3988,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,{"v":0.0006511,"d":"6.51E-04"},"[-0.00059-0.00189] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[15,"rs33951980",7,73020337,"rs3812316","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs3812316-C","rs3812316",0,3812316,"missense_variant",0,0.876,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.0221,"[0.015-0.029] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[17,"rs117026536",8,19819724,"rs328","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(TG)",0.071,"[0.026-0.116] mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[30,"rs559115405",16,14674204,"rs112210983","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","16p13.12",null,"PARN",null,null,"ENSG00000140694",null,null,"rs112210983-A","rs112210983",0,112210983,"intron_variant",0,0.2308,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.0105,"[0.0072-0.0138] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[34,"rs16940904",17,43682323,"rs186806998","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FEV1)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","LOC644172, CRHR1","MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,2617,3614,"rs186806998-T","rs186806998",1,56383763,"intergenic_variant",1,0.82,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,29.5,"[20.29-38.71] ml increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,null,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,3.34,"[2.03-4.65] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(CD200R1L)",0.32238275,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,63085997,"rs12239736","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12239736-A","rs12239736",0,12239736,"intron_variant",0,0.352174,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.07167609,"[0.049-0.094] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27734972,"rs6547692","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Lactate dehydrogenase levels","126,319 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs6547692-?","rs6547692",0,6547692,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.02508,"[0.017-0.033] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-11-25",26833098,"Kilpelainen TO","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833098","Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.","circulating leptin levels adjusted for BMI","up to 14,094 European ancestry men, up to 19,893 European ancestry women","up to 9,076 European ancestry men, up to 9,150 European ancestry women","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,0.61,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.024,"[0.016-0.032] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.161,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(Hispanic)",0.104,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.029,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs2727263",11,61603358,"rs2727271","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Albumin-globulin ratio","98,626 Japanese ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs2727271-?","rs2727271",0,2727271,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.03124,"[0.021-0.041] unit decrease novel","Illumina [6108953] (imputed)","N"]
[25,"rs10899133",11,75531695,"rs10899133","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","11q13.5","UVRAG","UVRAG",null,null,"ENSG00000198382",null,null,"rs10899133-T","rs10899133",0,10899133,"intron_variant",0,0.1063,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.03597418,"[0.025-0.047] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.716,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(EA)",0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs118146573",16,57000938,"rs118146573","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","Cholesterol, total","3,701 Mexican ancestry individuals","5,114 Mexican ancestry individuals, 903 Mexican ancestry individuals from 73 dyslipidemic families","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-A","rs118146573",0,118146573,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.2,"[NR] unit decrease","Illumina [1661241] (imputed)","N"]
[34,"rs56755526",17,44762589,"rs77819282","2019-01-14",30367059,"Teumer A","2018-10-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30367059","Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.","Thyroid stimulating hormone levels","54,288 European ancestry individuals","up to 22,383 European ancestry individuals","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs77819282-A","rs77819282",1,199461,"intron_variant",0,0.24,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.043,"[0.029-0.057] unit increase","Affymetrix, Illumina [8048941] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(HDL.large, whole)",0.312,"[NR] unit decrease","Illumina [335603]","N"]
[38,"rs7412",19,45412079,"rs7412","2017-07-01",28135244,"Warren HR","2017-01-30","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28135244","Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.","Pulse pressure","140,886 European ancestry individuals","190,318 European ancestry individuals","19q13.32","chr19mb45","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078406042,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.3826,"[0.26-0.5] unit decrease","Affymetrix [~ 9800000] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA, Repulsive guidance molecule A)",0.3237,"[0.22-0.42] unit decrease","Affymetrix [509946]","N"]
[11,"rs59136961",6,34548206,"rs2744939","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","6p21.31",null,"AL031577.1 - C6orf106","ENSG00000196114","ENSG00000196821",null,3773,6859,"rs2744939-?","rs2744939",0,2744939,"intergenic_variant",1,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[11,"rs59136961",6,34773727,"rs2395607","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs2395607-?","rs2395607",0,2395607,"intron_variant",0,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[18,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,0.485,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA)",0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65121565,"rs12355784","2008-12-01",18940312,"Yuan X","2008-10-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18940312","Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.","Liver enzyme levels","7,751 European ancestry individuals","1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs12355784-A","rs12355784",0,12355784,"intron_variant",0,0.48,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(ALP)",0.03,"[0.017-0.033] U/L increase","Affymetrix, Illumina [up to 496032]","N"]
[24,"rs653264",11,68699775,"rs653264","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","11q13.3",null,"IGHMBP2",null,null,"ENSG00000132740",null,null,"rs653264-?","rs653264",0,653264,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[28,"rs139974673",15,44028047,"rs147233090","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","15q15.3","CATSPER2P1","CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs147233090-T","rs147233090",0,147233090,"intron_variant",0,0.0241,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.073863,"[0.051-0.097] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,44096553,"rs62062288","2018-12-14",30336701,"Sanchez-Roige S","2018-10-19","Am J Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30336701","Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.","Alcohol use disorder (total score)","141,932 European ancestry individuals","NA","17q21.31","CRHR1, DND1P1, ENSG00000262372, ENSG00000262500, ENSG00000262881, KANSL1, MAPT, MAPT-AS1, NSF, PLEKHM1, SPPL2C, STH, RP11-105N13.4, WNT3","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,6.21,"[NR] z score decrease","NR [16213998]","N"]
[34,"rs16940904",17,44227393,"rs2696579","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2696579-A","rs2696579",0,2696579,"intron_variant",0,0.3371,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.02511521,"[0.017-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.321,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(AA)",0.171,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2011-04-11",21378988,"Coronary Artery Disease (C4D) Genetics Consortium","2011-03-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21378988","A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.","Coronary heart disease","8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls","18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,1.14,"[1.09-1.19]","Illumina [574919]","N"]
[15,"rs138574868",7,72977898,"rs12539316","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Gamma glutamyl transpeptidase","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","7q11.23","TBL2","BCL7B - TBL2","ENSG00000106635","ENSG00000106638",null,5566,3965,"rs12539316-C","rs12539316",0,12539316,"intergenic_variant",1,0.1,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.0051,"[0.0035-0.0067] IU/L increase","Affymetrix [~ 2200000] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2014-03-22",24023261,"Keller M","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023261","THOC5: a novel gene involved in HDL-cholesterol metabolism.","Lipid traits","839 European ancestry individuals","up to 5,248 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.09,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(Triglycerides)",0.24,"unit decrease","Affymetrix [390619]","N"]
[23,"rs509360",11,61548559,"rs509360","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","MYRF, TMEM258",null,null,"ENSG00000124920, ENSG00000134825",null,null,"rs509360-A","rs509360",0,509360,"intron_variant",0,0.3148,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(Cis/trans-18:2, EA)",0.0031,"[0.0021-0.0041] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.4905,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.0405,"[0.028-0.053] unit decrease","NR [8041861] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(TP53I11)",0.31360647,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(VLDL.small, whole)",1.323,"[NR] unit decrease","Illumina [335603]","N"]
[10,"rs272863",5,131677997,"rs272869","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference adjusted for body mass index","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4038,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(EA)",0.0212,"[0.015-0.028] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[15,"rs62466318",7,73042085,"rs62466318","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.204,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,0.01704703,"[0.012-0.022] unit increase","Affymetrix [11514936] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(EA)",0.044,"[0.03-0.058] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65274927,"rs10761779","2008-12-01",18940312,"Yuan X","2008-10-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18940312","Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.","Liver enzyme levels","7,751 European ancestry individuals","1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals","10q21.3","REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761779-G","rs10761779",0,10761779,"intron_variant",0,0.49,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(ALP)",0.03,"[0.017-0.033] U/L increase","Affymetrix, Illumina [up to 496032]","N"]
[23,"rs10897232",11,61939119,"rs10897221","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","11q12.3",null,"EEF1DP8 - SCGB1D1","ENSG00000236607","ENSG00000168515",null,1819,18569,"rs10897221-?","rs10897221",0,10897221,"regulatory_region_variant",1,"NR",{"v":7e-10,"d":"7.00E-10"},9.15490195998574,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.49,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(East Asian)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44096553,"rs62062288","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling guilty","373,380 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.211505,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,6.17,"z score increase","NR [10847151] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(SUMF1)",0.31651577,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.02209369,"[0.015-0.029] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27734972,"rs6547692","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Chloride levels","126,402 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs6547692-?","rs6547692",0,6547692,"intron_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.02467,"[0.017-0.033] unit increase","Illumina [6108953] (imputed)","N"]
[17,"rs117026536",8,19821782,"rs77069344","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs77069344-G","rs77069344",0,77069344,"intron_variant",0,0.099,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.2008,"[0.14-0.26] unit increase","Illumina [at least 9000000] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs525028",11,116710968,"rs613808","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FVC)","approximately 372,000 European ancestry individuals","NA","11q23.3",null,"APOA1-AS",null,null,"ENSG00000235910",null,null,"rs613808-?","rs613808",0,613808,"intron_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs1077835",15,58723939,"rs2070895","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-G","rs2070895",0,2070895,"intron_variant",0,0.77,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.1424,"[0.097-0.188] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[30,"rs72789541",16,15138413,"rs3803573","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","16p13.11","NR","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs3803573-?","rs3803573",0,3803573,"non_coding_transcript_exon_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.14809,"[0.1-0.2] unit decrease","Affymetrix [7794483] (imputed)","N"]
[33,"rs72836561",17,41840849,"rs77697917","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum eosinophil basophil counts","171,771 European ancestry individuals","NA","17q21.31","SOST","SOST - DUSP3","ENSG00000167941","ENSG00000108861",null,4693,2640,"rs77697917-T","rs77697917",0,77697917,"intergenic_variant",1,0.0286,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.06580746,"[0.045-0.087] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2015-05-05",22139419,"Gieger C","2011-11-30","Nature","www.ncbi.nlm.nih.gov/pubmed/22139419","New gene functions in megakaryopoiesis and platelet formation.","Platelet count","38,891 European ancestry individuals, 1,661 Val Borbera (founder/genetic isolate) individuals, 521 Carlantino (founder/genetic isolate) individuals, 1,198 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,213 South Tyrolean (founder/genetic isolate) individuals, 890 Sorbian (founder/genetic isolate) individuals, 4,292 Sardinian (founder/genetic isolate) individuals","Up to 16,949 European ancestry individuals, 854 Cliento (founder/genetic isolate) individuals, 1,035 Talana (founder/genetic isolate) individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,2.334,"[1.59-3.08] 10^9/l increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference adjusted for BMI","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.8425,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(EA,men)",0.0433,"[0.029-0.057] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[23,"rs7943992",11,61272565,"rs7125196","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","11q12.2",null,"AP003108.1 - MIR4488","ENSG00000255931","ENSG00000266006",null,5017,3503,"rs7125196-?","rs7125196",0,7125196,"intergenic_variant",1,"NR",{"v":9e-10,"d":"9.00E-10"},9.04575749056067,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs16940904",17,43685698,"rs143246821","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FEV1)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","LOC644172, CRHR1","MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,5992,239,"rs143246821-A","rs143246821",1,444967,"intergenic_variant",1,0.79,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(EA)",30.58,"[20.8-40.36] ml increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[37,"rs58542926",19,19702384,"rs17217098","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte percentage of white cells","171,748 European ancestry individuals","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs17217098-A","rs17217098",0,17217098,"intron_variant",0,0.0677,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,0.04375895,"[0.03-0.058] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs7412",19,45415640,"rs445925","2016-11-01",27179730,"Allen NB","2016-01-23","Am Heart J","www.ncbi.nlm.nih.gov/pubmed/27179730","Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies.","Ideal cardiovascular health (clinical)","2,242 European ancestry individuals with clinical ideal cardiovascular health, 9,466 European ancestry individuals without clinical ideal cardiovascular health","522 European ancestry individuals","19q13.32","APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.14,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,1.72,null,"Affymetrix [~ 25000000] (imputed)","N"]
[4,"rs11122450",1,230295789,"rs10127775","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs10127775-?","rs10127775",0,10127775,"intron_variant",0,0.44,{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2008-09-15",18262040,"Sandhu MS","2008-02-09","Lancet","www.ncbi.nlm.nih.gov/pubmed/18262040","LDL-cholesterol concentrations: a genome-wide association study.","LDL cholesterol","11,685 European ancestry individuals","Up to 4,979 European ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-T","rs562338",0,562338,"intergenic_variant",1,0.2,{"v":1e-09,"d":"1.00E-09"},9,null,0.04,"[0.02-0.06] mmol/L decrease","Affymetrix, Illumina [up to 461986]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-02-20",29385134,"Kawaguchi T","2018-01-31","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29385134","Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.","Nonalcoholic fatty liver disease","902 Japanese ancestry cases, 7,672 Japanese ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.57,{"v":1e-09,"d":"1.00E-09"},9,null,1.38,"[1.25-1.53]","Illumina [93606]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Isoleucine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-09,"d":"1.00E-09"},9,null,0.06,"[0.036-0.084] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[6,"rs77200710",2,27851918,"rs3749147","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","2p23.3","CCDC121","GPN1, AC074091.1",null,null,"ENSG00000198522, ENSG00000259080",null,null,"rs3749147-C","rs3749147",0,3749147,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.18,"[0.12-0.24] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index","up to 309,889 European ancestry individuals","NA","2q21.3","ZRANB3, MIR128-1, R3HDM1, LCT, LOC100507600, UBXN4, DARS, CXCR4","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.665850251591651,{"v":1e-09,"d":"1.00E-09"},9,null,0.0183999,"unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[11,"rs59136961",6,34785079,"rs73419621","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","6p21.31",null,"UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs73419621-?","rs73419621",0,73419621,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[15,"rs62466318",7,72977249,"rs34594435","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","7q11.23","BCL7B, TBL2","BCL7B - TBL2","ENSG00000106635","ENSG00000106638",null,4917,4614,"rs34594435-C","rs34594435",0,34594435,"intergenic_variant",1,null,{"v":1e-09,"d":"1.00E-09"},9,null,0.183,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[15,"rs33951980",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2012-01-10",22171074,"Tan A","2011-12-30","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/22171074","A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.","Triglycerides","1,999 Han Chinese ancestry male individuals","1,496 Han Chinese ancestry male individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-?","rs328",0,328,"stop_gained",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"Illumina [1940243] (imputed)","N"]
[18,"rs2954021",8,126479315,"rs6982636","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982636-?","rs6982636",0,6982636,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(TG.assay, whole)",0.033,"[NR] unit decrease","Illumina [335603]","N"]
[18,"rs33924196",8,126481475,"rs2980879","2012-05-10",22479202,"Dastani Z","2012-03-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22479202","Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.","Adiponectin levels","29,347 European ancestry individuals, 4,232 African American individuals, 1,776 Filipino ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980879-T","rs2980879",0,2980879,"intron_variant",0,0.69,{"v":1e-09,"d":"1.00E-09"},9,null,0.03,"[0.022-0.038] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[20,"10:22255616_CT_C",10,22288132,"rs4748779","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Smoking status (ever vs never smokers)","518,633 European ancestry individuals","NA","10p12.31","EBLN1","DNAJC1",null,null,"ENSG00000136770",null,null,"rs4748779-T","rs4748779",0,4748779,"intron_variant",0,0.7244,{"v":1e-09,"d":"1.00E-09"},9,null,0.013735452,"[0.0093-0.0181] unit decrease","Affymetrix [11514654] (imputed)","N"]
[21,"rs7924036",10,65308750,"rs10761784","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs10761784-A","rs10761784",0,10761784,"intron_variant",0,0.51,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",0.014,"NR unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[23,"rs198459",11,61471678,"rs198457","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Depressive symptoms","1,067,913 European ancestry individuals","228,033 European ancestry individuals","11q12.2","NR","DAGLA",null,null,"ENSG00000134780",null,null,"rs198457-T","rs198457",0,198457,"intron_variant",0,0.18779776750139,{"v":1e-09,"d":"1.00E-09"},9,null,0.007265015,"[0.0049-0.0096] unit decrease","NR [NR]","N"]
[23,"rs198459",11,61471678,"rs198457","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Neuroticism","523,783 European ancestry individuals","59,206 European ancestry individuals","11q12.2","NR","DAGLA",null,null,"ENSG00000134780",null,null,"rs198457-T","rs198457",0,198457,"intron_variant",0,0.18779776750139,{"v":1e-09,"d":"1.00E-09"},9,null,0.011377572,"[0.0077-0.0151] unit decrease","NR [NR]","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.6,{"v":1e-09,"d":"1.00E-09"},9,"(Hispanic)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.599,{"v":1e-09,"d":"1.00E-09"},9,"(Hispanic)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993161,"rs12149545","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14386,2601,"rs12149545-A","rs12149545",0,12149545,"regulatory_region_variant",1,0.3035,{"v":1e-09,"d":"1.00E-09"},9,null,0.0374,"[0.025-0.05] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[34,"rs16940904",17,43682323,"rs186806998","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FEV1)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","CRHR1","MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,2617,3614,"rs186806998-T","rs186806998",1,56383763,"intergenic_variant",1,0.79,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",36.39,"[24.71-48.07] unit increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[34,"rs9303521",17,43805194,"rs9303521","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs9303521T","rs9303521",0,9303521,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.01413,"[0.0096-0.0187] unit increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs16940904",17,43903842,"rs62057151","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling worry","372,869 European ancestry individuals","NA","17q21.31","NR","CRHR1, LINC02210-CRHR1, LINC02210-CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs62057151-T","rs62057151",0,62057151,"non_coding_transcript_exon_variant",0,0.223812,{"v":1e-09,"d":"1.00E-09"},9,null,6.049,"unit increase","NR [10847151] (imputed)","N"]
[34,"rs16940904",17,43923683,"rs12185268","2016-07-08",26077951,"Kouri N","2015-06-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26077951","Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.","Corticobasal degeneration","152 cases, 1,986 controls","NA","17q21.31","MAPT","MAPT-AS1, MAPT-AS1, MAPT-AS1, SPPL2C, SPPL2C, SPPL2C",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000277106, ENSG00000185294, ENSG00000278194",null,null,"rs12185268-?","rs12185268",0,12185268,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,3.46,"[2.27-5.28]","Illumina [533898] (imputed)","N"]
[34,"rs16940904",17,44224940,"rs80103986","2018-02-02",29313844,"Willems SM","2017-07-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29313844","Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.","Hand grip strength","142,035 European ancestry individuals","53,145 European ancestry individuals","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs80103986-A","rs80103986",0,80103986,"intron_variant",0,0.805,{"v":1e-09,"d":"1.00E-09"},9,null,0.171,"[0.12-0.23] kg increase","Affymetrix [at least 17000000] (imputed)","N"]
[34,"rs16940904",17,44847834,"rs199525","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FEV1)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199525-T","rs199525",0,199525,"intron_variant",0,0.8,{"v":1e-09,"d":"1.00E-09"},9,null,18.85,"[12.81-24.89] ml increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[35,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(HDL.large, fasting)",0.353,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs12965067",18,47229717,"rs9964304","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","18q21.1","intergenic","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,52187,36476,"rs9964304-A","rs9964304",0,9964304,"intergenic_variant",1,0.714,{"v":1e-09,"d":"1.00E-09"},9,null,0.043,"[0.029-0.057] unit decrease","Affymetrix [7947838] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.9,{"v":1e-09,"d":"1.00E-09"},9,"(Hispanic)",0.153,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs61061000",19,19263938,"rs58190593","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Mean arterial pressure","136,482 Japanese ancestry individuals","NA","19p13.11","MEF2B, MEF2BNB-MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-?","rs58190593",0,58190593,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.02567,"[0.017-0.034] unit increase novel","Illumina [6108953] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",0.054,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[2,"rs638714",1,63118196,"rs10889353","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.14,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.126,"[0.085-0.167] unit decrease","Illumina [561583]","N"]
[3,"rs6657811",1,109807283,"rs6657811","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-T","rs6657811",0,6657811,"intron_variant",0,0.12,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.057,"[0.039-0.075] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[5,"rs12618122",2,21328825,"rs312945","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","2p24.1",null,"APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,61880,17964,"rs312945-A","rs312945",0,312945,"intergenic_variant",1,0.3051,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0091,"[0.0062-0.012] unit decrease","Affymetrix, Illumina [10000000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","White blood cell count","107,964 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0256,"[0.017-0.034] unit decrease novel","Illumina [6108953] (imputed)","N"]
[6,"rs77200710",2,27801759,"rs1919128","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919128-A","rs1919128",0,1919128,"missense_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.18,"[0.12-0.24] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[7,"rs11681659",2,135954797,"rs1375131","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","2q21.3","Intergenic","ZRANB3",null,null,"ENSG00000121988",null,null,"rs1375131-T","rs1375131",0,1375131,"3_prime_UTR_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0345404,"[0.023-0.046] unit increase","Illumina [13520550] (imputed)","N"]
[15,"rs33951980",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.8759,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0207,"[0.014-0.028] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[15,"rs33951980",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.8797,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02,"[0.014-0.026] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","8p23.1","LOC157273, PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.09,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(EA)",0.06,"[0.040-0.080] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","8p23.1","PPP1R3B, TNKS","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-?","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.15,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[17,"rs117026536",8,19830921,"rs10096633","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-A","rs10096633",0,10096633,"regulatory_region_variant",1,0.1,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(Indian)",13.66,"[9.21-18.11] unit decrease","Illumina [551825]","N"]
[17,"rs117026536",8,19919655,"rs4128744","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,94885,16970,"rs4128744-A","rs4128744",0,4128744,"regulatory_region_variant",1,0.11,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(Indian)",13.59,"[9.12-18.06] unit decrease","Illumina [551825]","N"]
[18,"rs2954021",8,126491733,"rs2954031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-T","rs2954031",0,2954031,"intron_variant",0,0.4452,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02164556,"[0.015-0.029] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[18,"rs35309034",8,126498828,"rs4870941","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-?","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.15755,"[0.11-0.21] unit decrease","Affymetrix [7794483] (imputed)","N"]
[23,"rs2924438",11,61313525,"rs77128898","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Cognitive performance","257,841 European ancestry individuals","NA","11q12.2","Intergenic","SYT7",null,null,"ENSG00000011347",null,null,"rs77128898-T","rs77128898",0,77128898,"missense_variant",0,0.0358,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0463,"[0.031-0.061] unit decrease","Affymetrix, Illumina [10100000] (imputed)","N"]
[23,"rs2521572",11,61711475,"rs2521572","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.3","BEST1","RNU6-1243P - BEST1","ENSG00000200898","ENSG00000167995",null,6003,5818,"rs2521572-T","rs2521572",0,2521572,"regulatory_region_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.05,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[31,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-03-14",30263045,"Blackburn NB","2018-09-17","BMC Proc","www.ncbi.nlm.nih.gov/pubmed/30263045","Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships.","Response to fenofibrate (HDL cholesterol levels)","817 individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.332,"[0.22-0.44] unit increase","NR [718407]","N"]
[34,"rs16940904",17,44006601,"rs17564829","2018-05-14",22961000,"Liu JZ","2012-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22961000","Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.","Primary biliary cirrhosis","2,861 British and Irish ancestry cases, 8,514 British and Irish ancestry controls","NA","17q21.31","CRHR1, MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17564829-G","rs17564829",0,17564829,"intron_variant",0,0.24,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1.25,"[1.16-1.35]","Illumina [237619] (imputed)","N"]
[34,"rs16940904",17,44096553,"rs62062288","2018-12-14",30336701,"Sanchez-Roige S","2018-10-19","Am J Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30336701","Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.","Alcohol use disorder (consumption score)","121,604 British ancestry individuals","NA","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.008,"[0.006-0.01] unit decrease","NR [16213998]","N"]
[36,"rs2278426",19,11350488,"rs2278426","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","19p13.2","NR","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.03563,"[0.024-0.047] unit decrease novel","Illumina [6108953] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2012-11-19",23067351,"Rasmussen-Torvik LJ","2012-08-23","Clin Transl Sci","www.ncbi.nlm.nih.gov/pubmed/23067351","High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE.","LDL cholesterol","1,249 African American individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,0.1,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,12.3,"[8.4-16.3] mg/dL decrease","Illumina [910341]","N"]
[5,"rs7419374",2,21414142,"rs503662","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","LDL cholesterol","7,565 African American individuals","3,789 African American and Afro-Caribbean individuals","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,47998,7248,"rs503662-T","rs503662",0,503662,"intergenic_variant",1,0.652,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.11,"[0.075-0.145] unit decrease","Affymetrix [~ 2740000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-06-22",22558069,"Osman W","2012-04-27","PLoS One","www.ncbi.nlm.nih.gov/pubmed/22558069","Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.","Non-albumin protein levels","Up to 9,103 Japanese ancestry individuals","Up to 1,629 Japanese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.445,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(ALB)",0.08,"[0.053-0.107] unit decrease","Illumina [2178644] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"Affymetrix [344366]","N"]
[7,"rs11399929",2,136322676,"rs6759321","2018-07-09",29691431,"Tikkanen E","2018-04-24","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29691431","Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.","Hand grip strength","223,215 British ancestry individuals","111,610 British ancestry individuals","2q21.3","R3HDM1","R3HDM1",null,null,"ENSG00000048991",null,null,"rs6759321-T","rs6759321",0,6759321,"intron_variant",0,0.24,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,2E-3,"[0.0012-0.0028] unit increase","Affymetrix [15275733] (imputed)","N"]
[15,"rs33951980",7,73026378,"rs17145750","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-C","rs17145750",0,17145750,"intron_variant",0,0.86,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,4.5,"[2.90-6.30] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[15,"rs33951980",7,73026378,"rs17145750","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-T","rs17145750",0,17145750,"intron_variant",0,0.1611,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.02935932,"[0.02-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183664,"rs4841133","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","8p23.1","RP11-115 J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841133-G","rs4841133",0,4841133,"non_coding_transcript_exon_variant",0,0.0929,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.11155177,"[0.075-0.148] mg/dl increase","Illumina [24111857] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.196,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Hispanic)",0.111,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126500031,"rs28601761","2018-10-19",30220432,"Haas ME","2018-09-06","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30220432","Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.","Urinary albumin excretion (no hypertensive medication)","302,687 European ancestry individuals without hypertensive medication","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.579,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.01059,"[0.0071-0.0141] unit increase","Affymetrix [11709857] (imputed)","N"]
[18,"rs35309034",8,126504726,"rs6987702","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6987702-G","rs6987702",0,6987702,"intron_variant",0,0.29,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(EA)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[23,"rs198459",11,61471678,"rs198457","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Well-being spectrum (multivariate analysis)","2,083,151 European ancestry individuals","287,239 European ancestry individuals","11q12.2","NR","DAGLA",null,null,"ENSG00000134780",null,null,"rs198457-T","rs198457",0,198457,"intron_variant",0,0.18779776750139,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.007003807,"[0.0047-0.0093] unit decrease","NR [NR]","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.548,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(East Asian)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.603,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Hispanic)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.4,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(HDL-C)",0.04,"[0.020-0.060] unit increase","Affymetrix [~ 3700000] (imputed)","N"]
[34,"rs16940904",17,43696159,"rs675600","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Myeloid white cell count","169,219 European ancestry individuals","NA","17q21.31","CRHR1-IT1, CRHR1, RP11-105N13.4","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,9875,1535,"rs675600-T","rs675600",0,675600,"intergenic_variant",1,0.2046,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.02733148,"[0.018-0.036] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,44083402,"rs1991556","2019-01-18",30531941,"Doherty A","2018-12-10","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30531941","GWAS identifies 14 loci for device-measured physical activity and sleep duration.","Sleep duration","91,105 European ancestry individuals","NA","17q21.31","STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1991556-G","rs1991556",0,1991556,"intron_variant",0,0.774711,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.03280479,"[0.022-0.044] SD units increase","NR [9926106] (imputed)","N"]
[34,"rs7225002",17,44189067,"rs7225002","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs7225002G","rs7225002",0,7225002,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.01401,"[0.0094-0.0186] unit increase","Affymetrix [10847151] (imputed)","N"]
[36,"rs2278426",19,11350488,"rs2278426","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","19p13.2","TSPAN16, SPC24, RAB3D, KANK2, DOCK6, LOC55908","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,0.3,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.14,"[0.1-0.18] unit decrease","Illumina [1361436] (imputed)","N"]
[37,"rs11882123",19,19473445,"rs2905424","2014-03-18",23974872,"Ripke S","2013-08-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23974872","Genome-wide association analysis identifies 13 new risk loci for schizophrenia.","Schizophrenia","5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls","4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios","19p13.11","CILP2, PBX4, MAU2, GMIP, LPAR2, MIR640, NCAN, GATAD2A, HAPLN4, YJEFN3, NDUFA13, SUGP1, TM6SF2, TSSK6","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,3881,23190,"rs2905424-T","rs2905424",0,2905424,"intergenic_variant",1,0.348,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,1.092,"[1.06-1.12]","Affymetrix, Illumina [9871789]","N"]
[37,"rs58542926",19,19658472,"rs16996148","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","19p13.11","NCAN, CILP2","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-G","rs16996148",0,16996148,"intergenic_variant",1,0.89,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,3.32,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[37,"rs58542926",19,19658472,"rs16996148","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","19p13.11","CILP2, NCAN","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-G","rs16996148",0,16996148,"intergenic_variant",1,0.92,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,6.1,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(MAPK8)",0.30471954,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[2,"rs638714",1,62931632,"rs1167998","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1167998-?","rs1167998",0,1167998,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(VLDL.small, fasting)",1.505,"[NR] unit decrease","Illumina [335603]","N"]
[3,"rs629301",1,109821511,"rs602633","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (father's attained age)","415,311 British ancestry individuals","NA","1p13.3","CLESR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2008-06-16",17634449,"Samani NJ","2007-07-18","N Engl J Med","www.ncbi.nlm.nih.gov/pubmed/17634449","Genomewide association analysis of coronary artery disease.","Coronary heart disease","1,926 European ancestry cases, 2,938 European ancestry controls","875 European ancestry cases, 1,644 European ancestry controls","1p13.3","PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.77,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,1.29,"[1.18-1.40]","Affymetrix [377857]","N"]
[6,"rs1260326",2,27741237,"rs780094","2015-04-24",25187374,"Hwang JY","2014-09-03","Diabetes","www.ncbi.nlm.nih.gov/pubmed/25187374","Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.","Fasting plasma glucose","24,740 East Asian ancestry individuals","21,345 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.052,"[0.034-0.070] unit increase","Affymetrix, Illumina [up to 2315813] (imputed)","N"]
[11,"rs59136961",6,34552797,"rs2814944","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","6p21.31","C6orf106","AL031577.1 - C6orf106","ENSG00000196114","ENSG00000196821",null,8364,2268,"rs2814944-A","rs2814944",0,2814944,"intergenic_variant",1,0.16,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.49,"[0.29-0.69] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[15,"rs33951980",7,73020337,"rs3812316","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women","up to 62,368 European ancestry women","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs3812316-C","rs3812316",0,3812316,"missense_variant",0,0.8809,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.0276,"[0.018-0.037] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[15,"rs33951980",7,73042443,"rs6460047","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum uric acid levels","109,029 Japanese ancestry individuals","NA","7q11.23","MLXIPL, VPS37D","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3570,39712,"rs6460047-?","rs6460047",0,6460047,"intergenic_variant",1,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.04096,"[0.027-0.055] unit decrease novel","Illumina [6108953] (imputed)","N"]
[17,"rs117026536",8,19905904,"rs78299715","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","8p21.3",null,"LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,81134,30721,"rs78299715-?","rs78299715",0,78299715,"intergenic_variant",1,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[18,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(Asian initial, BMI unadjusted)",0.049,"[0.033-0.065] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[21,"rs7924036",10,65308750,"rs10761784","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity or levels","24,075 European ancestry individuals, 3,420 African American individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs10761784-A","rs10761784",0,10761784,"intron_variant",0,0.53,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.011,"NR unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.833,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(AA)",0.169,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.075,"[0.05-0.1] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[37,"rs58542926",19,19610596,"rs3794991","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19p13.11","GATAD2A, CILP2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs3794991-T","rs3794991",0,3794991,"intron_variant",0,0.0775,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.077,"[0.052-0.102] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[37,"rs58542926",19,19658472,"rs16996148","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","19p13.11","CILP2, PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-T","rs16996148",0,16996148,"intergenic_variant",1,0.1,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.1,"[0.06-0.14] unit decrease","Affymetrix [389878]","N"]
[1,"rs11591147",1,55505647,"rs11591147","2012-03-14",22331829,"Chasman DI","2012-02-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22331829","Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.","Response to statins (LDL cholesterol change)","6,989 European ancestry individuals","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(baseline LDL-C)",5,"[3.43-6.57] mg/dL decrease","Illumina [814418]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-04-21",27899376,"Nakayama A","2016-11-29","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/27899376","GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.","Renal overload gout","560 Japanese ancestry cases, 1,213 Japanese ancestry controls","618 Japanese ancestry cases, 1,268 Japanese ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.535,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,1.35,"[1.22-1.49]","Illumina [570442]","N"]
[7,"rs11681659",2,136608646,"rs4988235","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","2q21.3","NR","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-G","rs4988235",0,4988235,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.016,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[11,"rs114863007",6,34728071,"rs75398113","2019-02-28",30677029,"Riveros-McKay F","2019-01-24","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/30677029","Genetic architecture of human thinness compared to severe obesity.","Obese vs. thin","1,456 British ancestry obese children, 1,471 European ancestry thin adults","up to 7,526 British ancestry obese individuals, 7,962 obese individuals, up to 3,532 British ancestry thin individuals, 8,106 thin individuals","6p21.31","SNRPC","SNRPC",null,null,"ENSG00000124562",null,null,"rs75398113-C","rs75398113",0,75398113,"intron_variant",0,0.0803933,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,1.3,"[1.19-1.42]","Illumina [41266535] (imputed)","N"]
[15,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.869,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(Hispanic)",0.12,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs33951980",7,73020337,"rs3812316","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women","up to 62,368 European ancestry women","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs3812316-C","rs3812316",0,3812316,"missense_variant",0,0.8761,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.0283,"[0.019-0.038] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[18,"rs2954021",8,126482077,"rs2954021","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alanine transaminase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.5,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,1.6,"[0.60-2.60] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.02379,"[0.016-0.032] unit decrease novel","Illumina [6108953] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.0384,"[0.025-0.051] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[23,"rs112657532",11,61722645,"rs1109748","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.3","BEST1","BEST1",null,null,"ENSG00000167995",null,null,"rs1109748-A","rs1109748",0,1109748,"synonymous_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.05,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[34,"rs16940904",17,44205690,"rs4471723","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling guilty","373,380 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs4471723-T","rs4471723",0,4471723,"intron_variant",0,0.219254,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,5.84,"z score increase","NR [10847151] (imputed)","N"]
[34,"rs2074404",17,44800046,"rs7224296","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs7224296-A","rs7224296",0,7224296,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.01891837,"[0.013-0.025] unit increase","Affymetrix [NR]","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.66,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(Hispanic)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(EA)",0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136092061,"rs1561277","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","2q21.3","ZRANB3","ZRANB3",null,null,"ENSG00000121988",null,null,"rs1561277-A","rs1561277",0,1561277,"intron_variant",0,0.3354,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(EA)",0.0239,"[0.016-0.032] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[7,"rs11681659",2,136806959,"rs925966","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2q21.3","NR","DARS-AS1 - AC068492.1","ENSG00000231890","ENSG00000237262",null,26796,28503,"rs925966-C","rs925966",0,925966,"intergenic_variant",1,0.3847,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.196,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(Hispanic)",0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19912370,"rs115849089","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin concentration","172,851 European ancestry individuals","NA","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.1165,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.0314433,"[0.021-0.042] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[18,"rs35309034",8,126501528,"rs7846135","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs7846135-?","rs7846135",0,7846135,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs525028",11,116710968,"rs613808","2019-02-01",30573740,"Yap CX","2018-12-20","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30573740","Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.","Male-pattern baldness","205,327 European ancestry males","NA","11q23.3","NR","APOA1-AS",null,null,"ENSG00000235910",null,null,"rs613808-A","rs613808",0,613808,"intron_variant",0,0.28105,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.0201897,"[0.013-0.027] unit increase","NR [19129689] (imputed)","N"]
[30,"rs72789541",16,15129970,"rs7200543","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs7200543-A","rs7200543",0,7200543,"synonymous_variant",0,0.681,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(Trans-ethnic initial)",0.021,"[0.014-0.028] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[34,"rs16940904",17,43696159,"rs675600","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","17q21.31","CRHR1-IT1, CRHR1, RP11-105N13.4","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,9875,1535,"rs675600-T","rs675600",0,675600,"intergenic_variant",1,0.2045,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.02652443,"[0.018-0.035] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,43925297,"rs17690703","2014-08-06",24429156,"Noth I","2013-04-17","Lancet Respir Med","www.ncbi.nlm.nih.gov/pubmed/24429156","Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.","Idiopathic pulmonary fibrosis","542 European ancestry cases, 542 European ancestry controls","868 European ancestry cases, 1,389 European ancestry controls","17q21.31","SPPL2C, KANSL1, MAPT, CRHR1, STH","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs17690703-C","rs17690703",0,17690703,"intron_variant",0,0.76,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,1.43,"[1.27-1.61]","Affymetrix [10601812] (imputed)","N"]
[34,"rs2435200",17,44071851,"rs2435200","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs2435200A","rs2435200",0,2435200,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.01363,"[0.009-0.0182] unit increase","Affymetrix [10847151] (imputed)","N"]
[3,"rs629301",1,109821511,"rs602633","2017-04-05",27899403,"Jones GT","2016-11-29","Circ Res","www.ncbi.nlm.nih.gov/pubmed/27899403","Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.","Abdominal aortic aneurysm","4,972 European ancestry cases, 99,858 European ancestry controls","2,482 European ancestry cases, 2,750 cases, 2,645 European ancestry controls, 5,263 controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.199,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.14,"[1.09-1.19]","Affymetrix, Illumina [5363770] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-?","rs599839",0,599839,"regulatory_region_variant",1,null,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.358,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Hispanic)",0.0688,"[NR] unit increase","Affymetrix [NR]","N"]
[11,"rs59136961",6,34563060,"rs2744977","2019-02-01",30573740,"Yap CX","2018-12-20","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30573740","Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.","Male-pattern baldness","205,327 European ancestry males","NA","6p21.31","NR","C6orf106",null,null,"ENSG00000196821",null,null,"rs2744977-G","rs2744977",0,2744977,"intron_variant",0,0.140382,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.0254041,"[0.017-0.034] unit decrease","NR [19129689] (imputed)","N"]
[16,"rs9987289",8,9187242,"rs1461729","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs1461729-T","rs1461729",0,1461729,"intron_variant",0,0.116,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(AA)",0.0355,"[NR] unit decrease","Affymetrix [NR]","N"]
[17,"rs117026536",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.903,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.05,"[1.03-1.08]","Affymetrix, Illumina [247470]","N"]
[18,"rs33924196",8,126481475,"rs2980879","2012-05-10",22479202,"Dastani Z","2012-03-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22479202","Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.","Adiponectin levels","29,347 European ancestry individuals","10,536 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980879-T","rs2980879",0,2980879,"intron_variant",0,0.7,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.03,"[0.020-0.040] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.647,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Hispanic)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs201220977",10,65066186,"rs10761741","2017-02-24",27225129,"Okbay A","2016-05-26","Nature","www.ncbi.nlm.nih.gov/pubmed/27225129","Genome-wide association study identifies 74 loci associated with educational attainment.","Educational attainment (years of education)","405,072 European ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.4237,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.013062275,"NR unit increase","Affymetrix, Illumina, Perlegen [~ 9300000] (imputed)","N"]
[23,"rs2727263",11,61603237,"rs2727270","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2727270-T","rs2727270",0,2727270,"intron_variant",0,0.1209,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Cis/trans-18:2, EA)",3.8E-3,"[0.0026-0.005] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[29,"rs1077835",15,58727325,"rs261332","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","15q21.3","RP11-355N15.1","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-G","rs261332",0,261332,"non_coding_transcript_exon_variant",0,0.792,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.02541862,"[0.017-0.034] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs11644601",16,15172118,"rs11644601","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","RRN3, PDXDC1",null,null,"ENSG00000085721, ENSG00000179889",null,null,"rs11644601-T","rs11644601",0,11644601,"intron_variant",0,"NR",{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2011-06-29",21665990,"Yu Y","2011-06-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21665990","Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.","Age-related macular degeneration","2,594 European ancestry cases, 4,134 European ancestry controls","5,640 European ancestry cases, 52,174 European ancestry controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.33,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.15,"[NR]","Affymetrix [6036699] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.869,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(AA)",0.217,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741105,"rs780095","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Fasting plasma glucose","15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780095-G","rs780095",0,780095,"intron_variant",0,0.4267,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(Non diabetics)",0.070907116,"[0.047-0.095] mmol/L increase","Illumina [24111857] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.6165,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.02097104,"[0.014-0.028] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs7012637",8,9173358,"rs7012814","2017-06-01",28107422,"de Vries PS","2017-01-20","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28107422","Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.","Fibrinogen levels","91,953 European ancestry individuals (imputed to 1000 Genomes)",null,"8p23.1","PPP1R3B, LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs7012814-?","rs7012814",0,7012814,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.0061,"unit increase","Affymetrix, Illumina [10883314] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0936,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,{"v":0.0006183,"d":"6.18E-04"},"[-0.00148-0.00272] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[18,"rs2954021",8,126479362,"rs6982502","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum total protein level","113,509 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982502-?","rs6982502",0,6982502,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.02423,"[0.016-0.032] unit decrease novel","Illumina [6108953] (imputed)","N"]
[18,"rs33924196",8,126484526,"rs2954026","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954026-G","rs2954026",0,2954026,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.16,"[0.10-0.22] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,43906828,"rs17689882","2015-11-03",25607358,"Hibar DP","2015-01-21","Nature","www.ncbi.nlm.nih.gov/pubmed/25607358","Common genetic variants influence human subcortical brain structures.","Subcortical brain region volumes","up to 13,171 European ancestry individuals","up to 15,130 European ancestry individuals, 545 Japanese ancestry individuals, 736 Mexican American individuals","17q21.31","CRHR1","CRHR1, LINC02210-CRHR1, LINC02210-CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs17689882-A","rs17689882",0,17689882,"intron_variant",0,0.22,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(Intracranial volume, EA)",13460.47,"[8891.61-18029.33] mm3 decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[34,"rs16940904",17,44187492,"rs17577094","2014-12-05",24842889,"Vacic V","2014-05-19","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/24842889","Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.","Parkinson's disease","1,130 Ashkenazi Jewish cases, 2,611 Ashkenazi Jewish controls","306 Ashkenazi Jewish cases, 2,583 Ashkenazi Jewish controls","17q21.31","MAPT","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs17577094-?","rs17577094",0,17577094,"intron_variant",0,0.74,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,1.56,"[1.39-1.79]","Affymetrix, Illumina [1069161] (imputed)","N"]
[37,"rs2285626",19,19425141,"rs12459676","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","19p13.11",null,"SUGP1",null,null,"ENSG00000105705",null,null,"rs12459676-?","rs12459676",0,12459676,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,"NR",{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,0.02,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[29,"rs28690720",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.861,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome","22,161 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,0.16,"[0.10-0.22] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[2,"rs638714",1,62922660,"rs4350231","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p31.3",null,"DOCK7",null,null,"ENSG00000116641",null,null,"rs4350231-?","rs4350231",0,4350231,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","Cholesterol, total","3,701 Mexican ancestry individuals","5,114 Mexican ancestry individuals, 903 Mexican ancestry individuals from 73 dyslipidemic families","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-A","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.15,"[NR] unit increase","Illumina [1661241] (imputed)","N"]
[4,"rs11122450",1,230296153,"rs10864726","2017-06-01",28107422,"de Vries PS","2017-01-20","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28107422","Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.","Fibrinogen levels","91,953 European ancestry individuals (imputed to 1000 Genomes)",null,"1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs10864726-?","rs10864726",0,10864726,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.0059,"unit increase","Affymetrix, Illumina [10883314] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","2p23.3","GCKR","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-T","rs4665972",0,4665972,"intron_variant",0,0.123,{"v":1E-8,"d":"1.00E-08"},8,"(AA)",0.065,"[NR] unit increase","Affymetrix [NR]","N"]
[7,"rs11681659",2,135837906,"rs7570971","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-T","rs7570971",0,7570971,"intron_variant",0,0.31,{"v":1E-8,"d":"1.00E-08"},8,null,1.18,"[0.75-1.61] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[11,"rs59136961",6,34827085,"rs9469913","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals","132,177 European ancestry individuals","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469913-A","rs9469913",0,9469913,"missense_variant",0,0.8471,{"v":1E-8,"d":"1.00E-08"},8,null,0.0207,"[0.014-0.028] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.168,{"v":1E-8,"d":"1.00E-08"},8,"(Hispanic)",0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","8p23.1","LOC100129150","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.25,"[0.17-0.33] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65337153,"rs10822184","2012-10-28",22936694,"Jin G","2012-08-30","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/22936694","Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.","Androgen levels","3,225 European ancestry male individuals","NA","10q21.3","JMJD1C","REEP3",null,null,"ENSG00000165476",null,null,"rs10822184-T","rs10822184",0,10822184,"intron_variant",0,0.49,{"v":1E-8,"d":"1.00E-08"},8,"(serum testosterone)",0.058,"[0.038-0.078] unit decrease","Illumina [642461]","N"]
[23,"rs546240759",11,61417472,"rs1692120","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","DAGLA","RPLP0P2 - AP002754.2","ENSG00000243742","ENSG00000255947",null,10551,4665,"rs1692120-A","rs1692120",0,1692120,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.01,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[23,"rs2727263",11,61601908,"rs2845573","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2845573-A","rs2845573",0,2845573,"intron_variant",0,0.9173,{"v":1E-8,"d":"1.00E-08"},8,"(Cis/trans-18:2, EA)",0.0044,"[0.0028-0.006] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[25,"rs673335",11,75455021,"rs499974","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q13.5","MOGAT2, DGAT2","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1550,14479,"rs499974-A","rs499974",0,499974,"regulatory_region_variant",1,0.19,{"v":1E-8,"d":"1.00E-08"},8,null,0.026,"[NR] unit decrease","NR [NR] (imputed)","N"]
[29,"rs261291",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.78,{"v":1E-8,"d":"1.00E-08"},8,"(Hispanic)",0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680954,"rs2043085","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043085-A","rs2043085",0,2043085,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,"(HDLC-GLUC)",0.17,"[0.11-0.23] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.27,{"v":1E-8,"d":"1.00E-08"},8,"(East Asian)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-03-14",30263045,"Blackburn NB","2018-09-17","BMC Proc","www.ncbi.nlm.nih.gov/pubmed/30263045","Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships.","High density lipoprotein cholesterol levels","817 individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.315,"[0.21-0.42] unit increase","NR [718407]","N"]
[31,"rs1864163",16,56997233,"rs1864163","2018-10-18",30108155,"Hebbar P","2018-08-14","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/30108155","Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population.","High density lipoprotein cholesterol levels","1,353 Kuwaiti ancestry individuals","1,176 Kuwaiti ancestry individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1864163-A","rs1864163",0,1864163,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,"(additive model)",5.707,"z-score decrease","Illumina [632375]","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.883,{"v":1E-8,"d":"1.00E-08"},8,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43516402,"rs17631303","2013-08-02",23544013,"Couch FJ","2013-03-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23544013","Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.","Ovarian cancer in BRCA1 mutation carriers","683 European ancestry cases, 2,044 European ancestry controls","1,706 European ancestry cases, 10,258 European ancestry controls","17q21.31","intergenic","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs17631303-G","rs17631303",0,17631303,"intron_variant",0,0.19,{"v":1E-8,"d":"1.00E-08"},8,null,1.27,"[1.17-1.38]","Illumina [2568349] (imputed)","N"]
[34,"rs16940904",17,43682323,"rs186806998","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FVC)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31",null,"MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,2617,3614,"rs186806998-?","rs186806998",1,56383763,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,30.52,"[20.01-41.03] unit increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[34,"rs16940904",17,43893716,"rs8072451","2015-11-03",25607358,"Hibar DP","2015-01-21","Nature","www.ncbi.nlm.nih.gov/pubmed/25607358","Common genetic variants influence human subcortical brain structures.","Subcortical brain region volumes","up to 13,171 European ancestry individuals","up to 15,130 European ancestry individuals, 545 Japanese ancestry individuals, 736 Mexican American individuals","17q21.31","MAPT, GRN, CRHR1, STH","CRHR1, LINC02210-CRHR1, LINC02210-CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs8072451-?","rs8072451",0,8072451,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,"(Intracranial volume, EA)",14489.99,"[9539.28-19440.70] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[34,"rs16940904",17,44162597,"rs8080583","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability","107,207 European ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs8080583-?","rs8080583",0,8080583,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,5.717,"z score decrease","Affymetrix, Illumina [7357080] (imputed)","N"]
[36,"rs2278426",19,11350488,"rs2278426","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","19p13.2",null,"ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs2278426",19,11350488,"rs2278426","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Total cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19p13.2","C19orf80, DOCK6","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-T","rs2278426",0,2278426,"missense_variant",0,0.273,{"v":1E-8,"d":"1.00E-08"},8,null,3.8231,"[2.51-5.13] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-08-18",28548082,"Southam L","2017-05-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28548082","Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.","Total cholesterol levels","up to 1,476 Mylopotamos (founder/genetic isolate) individuals, up to 1,737 Pomak (founder/genetic isolate) individuals","NA","19q13.32","APOC1, APOC2, APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.079,{"v":1E-8,"d":"1.00E-08"},8,null,0.27,"[0.18-0.36] unit decrease","Illumina [at least 13541454] (imputed)","N"]
[2,"rs10889363",1,63191777,"rs12130333","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","1p31.3","DOCK7, ANGPTL3, ATG4C","AC103923.1 - ATG4C","ENSG00000235545","ENSG00000125703",null,15412,58029,"rs12130333-T","rs12130333",0,12130333,"intergenic_variant",1,0.22,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.11,"[0.07-0.15] unit decrease","Affymetrix [389878]","N"]
[5,"rs12618122",2,21327635,"rs97458","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (MTAG)","1,311,438 European ancestry individuals","NA","2p24.1","Intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,60690,19154,"rs97458-A","rs97458",0,97458,"intergenic_variant",1,0.6957,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(MTAG)",0.008,"[0.0053-0.0107] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.4,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(TRIG)",0.082,"[0.053-0.111] mmol/l increase","Illumina [NR] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2016-01-22",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in obese individuals","4,613 European ancestry male individuals, 4,690 European ancestry female individuals, 142 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.6,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.085,"[0.056-0.114] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-03-14",27599772,"Ram R","2016-09-07","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/27599772","A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.","Hypertriglyceridemia","927 Saudi Arabian ancestry cases, 3,159 Saudi Arabian ancestry controls","317 Saudi Arabian ancestry cases, 1,098 Saudi Arabian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.22,"[1.01-1.48]","Affymetrix [~ 8000000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.369,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.467,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","2q21.3","NR","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-C","rs7570971",0,7570971,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.015,"[NR] unit increase","Affymetrix [at least 28613428] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","2q21.3","MCM6","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.6486,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.0217,"[0.014-0.029] unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[10,"rs272863",5,131677997,"rs272869","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist circumference adjusted for BMI (adjusted for smoking behaviour)","97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4005,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0194,"[0.013-0.026] unit decrease","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[10,"rs272863",5,131677997,"rs272869","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)","97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4005,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.842,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA,women)",0.0366,"[0.024-0.049] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[15,"rs62466318",7,72885810,"rs6976930","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","7q11.23","BAZ1B","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-?","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[18,"rs2954021",8,126479362,"rs6982502","2017-03-14",27599772,"Ram R","2016-09-07","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/27599772","A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.","Hypertriglyceridemia","927 Saudi Arabian ancestry cases, 3,159 Saudi Arabian ancestry controls","317 Saudi Arabian ancestry cases, 1,098 Saudi Arabian ancestry controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982502-C","rs6982502",0,6982502,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.35,"[1.05-2]","Affymetrix [~ 8000000] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8q24.13","TRIB1, LOC100130231","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,null,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.226,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[19,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"10:22255616_CT_C",10,21878144,"rs35587371","2019-02-14",30258056,"Vojinovic D","2018-09-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30258056","Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.","Lateral ventricular volume in normal aging","22,045 European ancestry individuals, 1,488 African American individuals","NA","10p12.31","MLLT10","MLLT10",null,null,"ENSG00000078403",null,null,"rs35587371-A","rs35587371",0,35587371,"intron_variant",0,0.3,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,5.61,"z score decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[21,"rs7924036",10,65314711,"rs2163188","2017-10-27",28892062,"Akiyama M","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892062","Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.","Body mass index","up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men","up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs2163188-C","rs2163188",0,2163188,"intron_variant",0,0.5,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.015,"[0.0091-0.0209] kg/m2 increase","Illumina [6108953] (imputed)","N"]
[23,"rs7943992",11,61272565,"rs7125196","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Systolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","11q12.2","MIR4488","AP003108.1 - MIR4488","ENSG00000255931","ENSG00000266006",null,5017,3503,"rs7125196-C","rs7125196",0,7125196,"intergenic_variant",1,0.8548,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.2642,"[0.17-0.36] mmHg increase","Affymetrix [NR] (imputed)","N"]
[23,"rs198422",11,61506468,"rs198442","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FVC)","approximately 372,000 European ancestry individuals","NA","11q12.2",null,"DAGLA",null,null,"ENSG00000134780",null,null,"rs198442-?","rs198442",0,198442,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[23,"rs61896141",11,61595564,"rs968567","2014-08-05",24390342,"Okada Y","2013-12-25","Nature","www.ncbi.nlm.nih.gov/pubmed/24390342","Genetics of rheumatoid arthritis contributes to biology and drug discovery.","Rheumatoid arthritis","up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls","up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-C","rs968567",0,968567,"5_prime_UTR_variant",0,0.83,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",1.12,"[1.07-1.16]","Affymetrix, Illumina [up to 9739303] (imputed)","N"]
[25,"rs673335",11,75455373,"rs600518","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q13.5","NR","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1902,14127,"rs600518-A","rs600518",0,600518,"regulatory_region_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.35,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.548,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680954,"rs2043085","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043085-T","rs2043085",0,2043085,"intron_variant",0,0.47,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(HDL)",0.012,"[0.00024-0.02376] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[30,"rs3198697",16,15129940,"rs3198697","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-T","rs3198697",0,3198697,"missense_variant",0,0.43,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.02,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[31,"rs9989419",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.022,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs546735951",17,43471489,"rs4763","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","17q21.31","NR","ARHGAP27, ARHGAP27, ARHGAP27",null,null,"ENSG00000276836, ENSG00000276907, ENSG00000159314",null,null,"rs4763-A","rs4763",0,4763,"3_prime_UTR_variant",0,0.1745,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.0464,"[0.03-0.063] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[34,"rs16940904",17,43666492,"rs112010353","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Self-reported math ability","564,698 European ancestry individuals","NA","17q21.31","Intergenic","AC126544.2 - AC126544.1","ENSG00000285668","ENSG00000280022",null,747,3495,"rs112010353-C","rs112010353",0,112010353,"intergenic_variant",1,0.8237,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0143,"[0.0092-0.0194] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[34,"rs35076622",17,43851498,"rs35909029","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs35909029T","rs35909029",0,35909029,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.01299,"[0.0085-0.0175] unit increase","Affymetrix [10847151] (imputed)","N"]
[34,"rs16940904",17,43927290,"rs17769552","2018-07-09",29691431,"Tikkanen E","2018-04-24","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29691431","Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.","Hand grip strength","334,825 British ancestry individuals","NA","17q21.31","SPPL2C","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs17769552-A","rs17769552",0,17769552,"intron_variant",0,0.2235,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,2E-3,"[0.0014-0.0026] unit decrease","Affymetrix [15275733] (imputed)","N"]
[34,"rs2074404",17,44863133,"rs916888","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs916888-T","rs916888",0,916888,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.019683955,"[0.013-0.027] unit increase","Affymetrix [NR]","N"]
[34,"rs2074404",17,44865603,"rs199498","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","17q21.31","NR","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199498-C","rs199498",0,199498,"intron_variant",0,0.2094,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.0433,"[0.028-0.058] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[37,"rs3761077",19,19336608,"rs2238675","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","LDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.887,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.125,"[0.082-0.168] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","19p13.11","NCAN, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.06,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.05,"[-0.03-0.13] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[37,"19:19510831_AT_A",19,19545099,"rs4808199","2018-02-20",29385134,"Kawaguchi T","2018-01-31","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29385134","Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.","Nonalcoholic fatty liver disease","902 Japanese ancestry cases, 7,672 Japanese ancestry controls","NA","19p13.11","GATAD2A, NCAN, TM6SF2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808199-A","rs4808199",0,4808199,"intron_variant",0,0.27,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.37,"[1.23-1.53]","Illumina [93606]","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2018-07-30",27618447,"Surendran P","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618447","Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.","Diastolic blood pressure","up to 165,276 European ancestry individuals, up to 27,487 South Asian ancestry individuals","up to 125,713 European ancestry individuals, up to 2,641 South Asian ancestry individuals, 4,632 Hispanic individuals, 22,077 African American individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.9146,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.292,"mmHg decrease","Illumina [242296]","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.634,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.022,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Gondoic acid (20:1n-9) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,2E-3,"[-0.00192-0.00592] unit decrease","Affymetrix, Illumina [2200000] (imputed)","N"]
[6,"rs1260326",2,27748624,"rs1260333","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2073,11629,"rs1260333-A","rs1260333",0,1260333,"intergenic_variant",1,0.52,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.773,"[1.15-2.4] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[6,"rs77200710",2,27761436,"rs4665988","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Creatine kinase levels","106,080 Japanese ancestry individuals","NA","2p23.3","GCKR, C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs4665988-?","rs4665988",0,4665988,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.02399,"[0.016-0.032] unit decrease novel","Illumina [6108953] (imputed)","N"]
[11,"rs114863007",6,34592090,"rs6907508","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6p21.31","C6orf106","C6orf106",null,null,"ENSG00000196821",null,null,"rs6907508-A","rs6907508",0,6907508,"intron_variant",0,0.888,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.0244,"[0.016-0.033] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.844,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(EA)",0.0262,"[0.017-0.036] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[15,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.865,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.161,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.112,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"10:22255616_CT_C",10,21894028,"rs11012750","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Smoking status","approximately 458,000 European ancestry individuals","NA","10p12.31",null,"MLLT10",null,null,"ENSG00000078403",null,null,"rs11012750-?","rs11012750",0,11012750,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[21,"rs7924036",10,65365385,"rs1896995","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs1896995-T","rs1896995",0,1896995,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.017029727,"[0.011-0.023] unit increase","Affymetrix [NR]","N"]
[23,"rs509360",11,61548559,"rs509360","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Red blood cell count","108,794 Japanese ancestry individuals","NA","11q12.2","MYRF","MYRF, TMEM258",null,null,"ENSG00000124920, ENSG00000134825",null,null,"rs509360-?","rs509360",0,509360,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.02414,"[0.016-0.033] unit increase novel","Illumina [6108953] (imputed)","N"]
[25,"rs673335",11,75455021,"rs499974","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q13.5","NR","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1550,14479,"rs499974-C","rs499974",0,499974,"regulatory_region_variant",1,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs139974673",15,43677979,"rs201393666","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","15q15.3","TUBGCP4","TUBGCP4",null,null,"ENSG00000137822",null,null,"rs201393666-A","rs201393666",0,201393666,"intron_variant",0,0.029,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.097,"[0.064-0.13] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[28,"rs139974673",15,43757184,"rs190543502","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","15q15.3","TP53BP1","TP53BP1",null,null,"ENSG00000067369",null,null,"rs190543502-C","rs190543502",0,190543502,"intron_variant",0,0.02721,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,7.61,"[4.92-10.3] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[30,"rs34936342",16,14753259,"rs34936342","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","16p13.12",null,"BFAR, BFAR",null,null,"ENSG00000103429, ENSG00000275618",null,null,"rs34936342-?","rs34936342",0,34936342,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs3764261",16,56987765,"rs56228609","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","16q13","CETP, HERPUD1","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8990,7997,"rs56228609-T","rs56228609",0,56228609,"intergenic_variant",1,0.303,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.039,"[0.025-0.053] unit decrease","Affymetrix [7947838] (imputed)","N"]
[31,"rs1864163",16,56997233,"rs1864163","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1864163-A","rs1864163",0,1864163,"intron_variant",0,0.13,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Asian initial, BMI unadjusted)",0.088,"[0.057-0.119] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[34,"rs9303521",17,43805194,"rs9303521","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","RP11-105N13.4","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs9303521-T","rs9303521",0,9303521,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.0097067,"[0.0063-0.0131] unit decrease","Affymetrix [18485882] (imputed)","N"]
[34,"rs7225002",17,44189067,"rs7225002","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs7225002-A","rs7225002",0,7225002,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.0096215,"[0.0062-0.013] unit increase","Affymetrix [18485882] (imputed)","N"]
[34,"rs56755526",17,44788310,"rs183211","2013-08-02",23544013,"Couch FJ","2013-03-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23544013","Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.","Ovarian cancer in BRCA1 mutation carriers","683 European ancestry cases, 2,044 European ancestry controls","1,706 European ancestry cases, 10,258 European ancestry controls","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs183211-?","rs183211",0,183211,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"Illumina [2568349] (imputed)","N"]
[37,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.874,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.121,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19658472,"rs16996148","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.11","CILP2, PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-T","rs16996148",0,16996148,"intergenic_variant",1,0.1,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.1,"[0.06-0.14] unit decrease","Affymetrix [389878]","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.897,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.125,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.639,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(Hispanic)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-?","rs2144300",0,2144300,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.03663,"[0.024-0.05] unit increase novel","Illumina [6108953] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-?","rs2144300",0,2144300,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.02985,"[0.019-0.041] unit decrease novel","Illumina [6108953] (imputed)","N"]
[4,"rs11122450",1,230307182,"rs4846922","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs4846922-T","rs4846922",0,4846922,"intron_variant",0,0.39,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(HDL)",0.08,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2008-06-22",18454146,"Chambers JC","2008-05-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18454146","Common genetic variation near MC4R is associated with waist circumference and insulin resistance.","Waist circumference and related phenotypes","2,684 Indian Asian ancestry male individuals","7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(triglycerides)",null,null,"Illumina [308067]","N"]
[16,"rs9987289",8,9183358,"rs9987289","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","8p23.1","LOC100129150","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(HDLC-WC)",0.24,"[0.16-0.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65005399,"rs7902343","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7902343-C","rs7902343",0,7902343,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65314711,"rs2163188","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","10q21.3","NR","REEP3",null,null,"ENSG00000165476",null,null,"rs2163188-G","rs2163188",0,2163188,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.015,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[23,"rs72914277",11,61384563,"rs12807999","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","11q12.2",null,"RPLP0P2",null,null,"ENSG00000243742",null,null,"rs12807999-?","rs12807999",0,12807999,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[23,"11:61648649_AAATG_A",11,61664757,"rs17764935","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","11q12.2",null,"FADS3 - RAB3IL1","ENSG00000221968","ENSG00000167994",null,5234,16,"rs17764935-?","rs17764935",0,17764935,"regulatory_region_variant",1,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[25,"rs72997616",11,75474195,"rs72997616","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q13.5","CTD-2530H12.1","AP001922.1, DGAT2",null,null,"ENSG00000247867, ENSG00000062282",null,null,"rs72997616-A","rs72997616",0,72997616,"intron_variant",0,0.1232,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.0243,"[0.016-0.033] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[34,"rs16940904",17,44355602,"rs2696532","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling guilty","373,380 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2696532-A","rs2696532",0,2696532,"intron_variant",0,0.212157,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,5.49,"z score decrease","NR [10847151] (imputed)","N"]
[34,"rs16940904",17,44837217,"rs199529","2018-10-10",30054594,"MacGregor S","2018-07-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30054594","Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.","Intraocular pressure","133,492 European ancestry individuals","NA","17q21.31","NSF","NSF - WNT3","ENSG00000073969","ENSG00000277641",null,2387,2655,"rs199529-?","rs199529",0,199529,"intergenic_variant",1,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.083,"[0.053-0.113] unit decrease","Affymetrix, Illumina [up to 40000000] (imputed)","N"]
[37,"rs11882123",19,19440066,"rs3764567","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","19p13.11","MAU2","MAU2",null,null,"ENSG00000129933",null,null,"rs3764567-T","rs3764567",0,3764567,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,1.045,"[1.03-1.06]","Illumina [6627481] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","19p13.11","CILP2, ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.09,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.07,"[0.04-0.10] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.655,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(Hispanic)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049819,"rs12042319","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs12042319-G","rs12042319",0,12042319,"3_prime_UTR_variant",0,0.81,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,2.229,"[1.44-3.02] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-T","rs2144300",0,2144300,"intron_variant",0,0.18,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(Asian initial, BMI adjusted)",0.056,"[0.036-0.076] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[6,"rs1260326",2,27741072,"rs780096","2018-03-05",29304378,"Medina-Gomez C","2018-01-04","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29304378","Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.","Total body bone mineral density","56,284 European ancestry individuals, up to 1,333 African American individuals, up to 9,328 admixed individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780096-C","rs780096",0,780096,"intron_variant",0,0.4406,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0311,"unit decrease","Affymetrix, Illumina [~ 23700000] (imputed)","N"]
[18,"rs33924196",8,126507308,"rs2980888","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","8q24.13","Intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980888-T","rs2980888",0,2980888,"intron_variant",0,0.285,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0506,"[NR] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[18,"rs35309034",8,126508746,"rs6989280","2018-01-15",27680694,"Horikoshi M","2016-10-13","Nature","www.ncbi.nlm.nih.gov/pubmed/27680694","Genome-wide associations for birth weight and correlations with adult disease.","Birth weight","133,903 European ancestry individuals, 6,635 African American individuals, 420 Turkish ancestry individuals, 365 Moroccan ancestry individuals, 395 Surinamese ancestry individuals, 840 Chinese ancestry individuals.","9,799 European ancestry individuals, 1,449 Filipino ancestry individuals.","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6989280-G","rs6989280",0,6989280,"intron_variant",0,0.7,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0221,"[0.014-0.03] unit increase","Affymetrix, Illumina [at least 22434434] (imputed)","N"]
[29,"rs1077835",15,58727325,"rs261332","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Total cholesterol levels","up to 33,431 European ancestry individuals","NA","15q21.3","LIPC, LIPC-AS1","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-T","rs261332",0,261332,"non_coding_transcript_exon_variant",0,0.1955,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.96994877,"[0.62-1.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs72789541",16,15130594,"rs6498540","2019-04-24",30453627,"Marklund M","2018-11-17","Nutrients","www.ncbi.nlm.nih.gov/pubmed/30453627","Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity.","Fatty acid desaturase activity (serum)","1,453 European ancestry individuals","NA","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs6498540-A","rs6498540",0,6498540,"3_prime_UTR_variant",0,0.71,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(D6D)",null,null,"Illumina [at least 738879] (imputed)","N"]
[34,"rs7225002",17,44189067,"rs7225002","2019-04-15",30696823,"Jones SE","2019-01-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30696823","Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.","Chronotype","449,734  European ancestry individuals","248,098 European ancestry individuals","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs7225002-G","rs7225002",0,7225002,"intron_variant",0,0.4084,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,1.0180612,null,"Affymetrix [11880941] (imputed)","N"]
[34,"rs549080390",17,44764775,"rs199460","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199460-?","rs199460",0,199460,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,5.447,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs111784051",19,45400747,"rs61679753","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs61679753-?","rs61679753",0,61679753,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[38,"rs12721109",19,45447221,"rs12721109","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-?","rs12721109",0,12721109,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[2,"rs638714",1,62996838,"rs1168013","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168013-G","rs1168013",0,1168013,"intron_variant",0,0.65,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.04,"[0.03-0.05] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[5,"rs380240",2,21428049,"rs312053","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","2p24.1",null,"AC067959.1 - AC018742.1","ENSG00000271629","ENSG00000233005",null,6281,15998,"rs312053-?","rs312053",0,312053,"intergenic_variant",1,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[15,"rs62466318",7,73005776,"rs35866503","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,12655,1748,"rs35866503-C","rs35866503",0,35866503,"intergenic_variant",1,0.82,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.015,"[0.0091-0.0209] unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[21,"rs201220977",10,65027610,"rs10761731","2016-11-30",26805783,"Schick UM","2016-01-21","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26805783","Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.","Platelet count","12,491 Hispanic/Latin American individuals","7,170 Hispanic/Latin American individuals","10q21.3","RCL1","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,0.31,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,4.81,"[3.07-6.55] unit increase","Illumina [2232944] (imputed)","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43513441,"rs11012","2010-02-05",20070850,"Edwards TL","2010-01-13","Ann Hum Genet","www.ncbi.nlm.nih.gov/pubmed/20070850","Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.","Parkinson's disease","1,752 European ancestry cases, 1,745 European ancestry controls","NA","17q21.31","MAPT, PLEKHM1, IMP5","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs11012-T","rs11012",0,11012,"3_prime_UTR_variant",0,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,1.43,"[1.27-1.61]","Illumina [495715] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2015-07-07",25288136,"Cornelis MC","2014-10-07","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25288136","Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.","Coffee consumption (cups per day)","91,462 European ancestry individuals","30,062 European ancestry individuals, 7,964 African American individuals","2p23.3","GCKR, FNDC4","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.04,"[0.020-0.060] unit decrease","Affymetrix, Illumina [2373958] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2017-08-21",28334935,"Raffield LM","2017-05-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334935","Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?","Iron status biomarkers (total iron binding capacity)","12,586 Hispanic/Latino individuals","NA","8p23.1","LOC157273, PP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.116,"[0.073-0.159] unit decrease","Illumina [27700000] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.392,{"v":7e-08,"d":"7.00E-08"},7.15490195998574,"(Filipino)",0.195,"[0.12-0.27] unit increase","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[34,"rs16940904",17,43685698,"rs143246821","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FVC)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31",null,"MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,5992,239,"rs143246821-?","rs143246821",1,444967,"intergenic_variant",1,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,"(EA)",30.54,"[19.45-41.63] unit increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[37,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2019-03-28",30510157,"Franceschini N","2018-12-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30510157","GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.","Carotid intima media thickness","Up to 71,128 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.18,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.0487,"[0.047-0.05] unit decrease","Affymetrix, Illumina [9574088] (imputed)","N"]
[11,"rs59136961",6,34773727,"rs2395607","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs2395607-T","rs2395607",0,2395607,"intron_variant",0,0.1724,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(EA)",0.03,"[0.019-0.041] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.842,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(EA, men)",0.0366,"[0.023-0.05] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[15,"rs33951980",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women","up to 62,368 European ancestry women","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.8791,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.0255,"[0.016-0.035] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[23,"rs2727263",11,61623793,"rs2526678","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2526678-A","rs2526678",0,2526678,"non_coding_transcript_exon_variant",0,0.0833,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(Cis/trans-18:2, EA)",4.3E-3,"[0.0027-0.0059] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[34,"rs16940904",17,43991272,"rs17563986","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability","107,207 European ancestry individuals","NA","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17563986-?","rs17563986",0,17563986,"intron_variant",0,"NR",{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,5.368,"z score increase","Affymetrix, Illumina [7357080] (imputed)","N"]
[34,"rs16940904",17,44073889,"rs1052553","2018-04-26",25751624,"Onengut-Gumuscu S","2015-04-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25751624","Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.","Type 1 diabetes","6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios","NA","17q21.31","Intergenic","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1052553-A","rs1052553",0,1052553,"synonymous_variant",0,0.76,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,1.1235955,null,"Illumina [135870]","N"]
[6,"rs1260326",2,27741237,"rs780094","2009-02-13",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","Triglycerides","2,659 European ancestry type 2 diabetes cases and controls","5,217 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.35,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,0.5,"(% variance) increase","Affymetrix [389878]","N"]
[11,"rs59136961",6,34763982,"rs9469890","2013-05-31",23449627,"Cousminer DL","2013-02-27","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/23449627","Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.","Pubertal anthropometrics","up to 5,043 European ancestry males, up to 5,756 European ancestry females","NA","6p21.31","C6orf106","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469890-C","rs9469890",0,9469890,"intron_variant",0,0.88,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(Pubertal growth)",0.12,"[0.077-0.163] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,65128619,"rs10761750","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Vascular endothelial growth factor levels","7,118 Finnish ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761750-G","rs10761750",0,10761750,"intron_variant",0,null,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,0.0903,"[0.057-0.123] SD units decrease","NR [10700000] (imputed)","N"]
[29,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.601,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(East Asian)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19494483,"rs150268548","2017-09-21",28736931,"Rotroff DM","2017-07-24","Clin Pharmacol Ther","www.ncbi.nlm.nih.gov/pubmed/28736931","Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.","LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes","781 European ancestry individuals, 138 African American ancestry individuals, 345 unknown ancestry individuals",null,"19p13.11","PBX4, MAU2","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,24919,2152,"rs150268548-?","rs150268548",0,150268548,"intergenic_variant",1,"NR",{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(EA)",0.028,"unit decrease","Affymetrix, Illumina [8129838] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2008-06-16",18179892,"Wallace C","2008-01-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18179892","Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.","LDL cholesterol","1,955 European ancestry hypertensive individuals","2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.24,{"v":1e-07,"d":"1.00E-07"},7,null,0.95,"[0.93-0.97] mMol/l increase","Affymetrix [400496]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.478,{"v":1e-07,"d":"1.00E-07"},7,"(East Asian)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1349849",4,69349893,"rs138151052","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","4q13.2","NR","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs138151052-T","rs138151052",1,13114070,"intron_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,0.027,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.168,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.105,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-?","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":1e-07,"d":"1.00E-07"},7,"(Indian)",null,null,"Illumina [551825]","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.529,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,64878118,"rs6479877","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Vascular endothelial growth factor levels","7,118 Finnish ancestry individuals","NA","10q21.3","NR","RNU6-543P - AL590502.1","ENSG00000199446","ENSG00000224301",null,8112,5580,"rs6479877-G","rs6479877",0,6479877,"intergenic_variant",1,null,{"v":1e-07,"d":"1.00E-07"},7,null,0.0897,"[0.056-0.123] SD units increase","NR [10700000] (imputed)","N"]
[21,"rs7924036",10,65005399,"rs7902343","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7902343-C","rs7902343",0,7902343,"intron_variant",0,0.535,{"v":1e-07,"d":"1.00E-07"},7,"(EA)",0.026,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.355,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1601935",15,58674695,"rs4775041","2008-12-11",19043545,"Gieger C","2008-11-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19043545","Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.","Metabolite levels","284 European ancestry male individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-?","rs4775041",0,4775041,"intron_variant",0,0.28,{"v":1e-07,"d":"1.00E-07"},7,"(PE)",null,null,"Affymetrix [187454]","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.569,{"v":1e-07,"d":"1.00E-07"},7,"(AA)",0.114,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2011-10-07",21909108,"Bis JC","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909108","Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.","Carotid intima media thickness","Up to 31,211 European ancestry individuals","10,553 European ancestry individuals, 687 Orcadian individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,"(Plaque)",0.1778,"[0.11-0.25] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[37,"rs61061000",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Diastolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.3413,{"v":1e-07,"d":"1.00E-07"},7,"(Japanese)",0.2807,"[0.18-0.38] unit increase","Illumina [6200000] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19793545,"rs56408111","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","19p13.11",null,"ZNF101",null,null,"ENSG00000181896",null,null,"rs56408111-?","rs56408111",0,56408111,"3_prime_UTR_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.629,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.905,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-03-20",27588450,"Mahajan A","2016-09-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27588450","Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.","Glomerular filtration rate","23,553 European ancestry individuals, 23,536 Japanese individuals, 16,325 Hispanic individuals, 8,224 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.83,"[0.52-1.14] unit decrease","Affymetrix, Illumina [at least 6581000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Leucine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.049,"[0.023-0.075] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-08-03",28485404,"Jorgenson E","2017-05-09","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28485404","Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.","Alcohol consumption (drinks per week)","23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.          ","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.41,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.034,"unit decrease","Affymetrix [NR] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.5895,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.0552,"[0.035-0.076] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[10,"rs272863",5,131677997,"rs272869","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference adjusted for body mass index","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4038,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA, men)",0.025,"[0.016-0.034] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[10,"rs272863",5,131677997,"rs272869","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist circumference adjusted for BMI in non-smokers","77,113 European ancestry women, 47,319 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men","16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4005,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.0205,"[0.013-0.028] unit decrease","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[11,"rs59136961",6,34827085,"rs9469913","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469913-T","rs9469913",0,9469913,"missense_variant",0,0.1823,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(women)",0.0385,"[0.024-0.053] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","8p23.1","PPP1R3B, LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.09,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.05,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.196,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19876746,"rs7016880","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,51976,59879,"rs7016880-?","rs7016880",0,7016880,"intergenic_variant",1,0.9,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,3.13,"[2.04-4.76]","Affymetrix [~ 2100000] (imputed)","N"]
[23,"rs198435",11,61494327,"rs4963243","2012-08-07",22610502,"Kennedy RB","2012-05-19","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/22610502","Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.","Immune reponse to smallpox (secreted IL-2)","Up to 512 European ancestry individuals, up to 199 African American individuals","NA","11q12.2","DAGLA","DAGLA",null,null,"ENSG00000134780",null,null,"rs4963243-A","rs4963243",0,4963243,"intron_variant",0,null,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(AA)",null,null,"Illumina [NR]","N"]
[35,"rs9304381",18,47181668,"rs2156552","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","18q21.1","LIPG, ACAA2","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.18,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.07,"[0.05-0.09] unit decrease","Affymetrix [389878]","N"]
[37,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(females)",0.01621,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[4,"rs11122450",1,230297659,"rs2281719","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2281719-T","rs2281719",0,2281719,"intron_variant",0,0.5775,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.0289,"[0.018-0.04] unit decrease","NR [8041861] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(TG)",0.07,"mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[15,"rs33951980",7,72864869,"rs714052","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","7q11.23","MIXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-G","rs714052",0,714052,"intron_variant",0,0.11,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.123,"[0.076-0.170] unit decrease","Illumina [561583]","N"]
[15,"rs33951980",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.908,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(East Asian)",0.13,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.53,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.076,"[0.047-0.105] unit decrease","Illumina [561583]","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.701,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Hispanic)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs56755526",17,44788310,"rs183211","2011-09-14",21812969,"Liu X","2011-08-03","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21812969","Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.","Parkinson's disease","268 Ashkenazi Jewish cases, 178 Ashkenazi Jewish controls","1,782 European ancestry cases, 1,658 European ancestry controls","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs183211-T","rs183211",0,183211,"intron_variant",0,0.24,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,{"$nulls":3},"Illumina [525124]","N"]
[37,"rs58542926",19,19407718,"rs10401969","2015-06-11",25246029,"DiStefano JK","2014-09-23","Acta Diabetol","www.ncbi.nlm.nih.gov/pubmed/25246029","Genome-wide analysis of hepatic lipid content in extreme obesity.","Hepatic lipid content in extreme obesity","1,868 European ancestry cases","NA","19p13.11","SUGP1","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-?","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,{"$nulls":3},"Illumina [605718]","N"]
[37,"rs58542926",19,19407718,"rs10401969","2017-12-11",22885922,"Morris AP","2012-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22885922","Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.","Type 2 diabetes","6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls","12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(men)",1.15,"[1.09-1.21]","Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[5,"rs562338",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11399929",2,136721603,"rs12615624","2018-06-29",28714469,"Langefeld CD","2017-07-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28714469","Transancestral mapping and genetic load in systemic lupus erythematosus.","Systemic lupus erythematosus","6,748 European ancestry cases, 11,516 European ancestry controls, 2,970 African American cases, 2,452 African American controls, 1,872 Hispanic cases, 2,016 Hispanic controls","NA","2q21.3","DARS","DARS",null,null,"ENSG00000115866",null,null,"rs12615624-?","rs12615624",0,12615624,"intron_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,1.1111112,"[1.08-1.16]","Illumina [at least 5000000] (imputed)","N"]
[21,"rs7924036",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.05,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.954,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(AA)",0.262,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,62920008,"rs636523","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs636523-G","rs636523",0,636523,"non_coding_transcript_exon_variant",0,0.2,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(LDL)",0.021,"mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-12-11",22885922,"Morris AP","2012-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22885922","Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.","Type 2 diabetes","6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls","12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.613751766081311,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,1.06,"[1.04-1.09]","Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2009-02-13",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","Triglycerides","2,659 European ancestry type 2 diabetes cases and controls","5,217 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.1,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,1,"(% variance) increase","Affymetrix [389878]","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.294,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15129459,"rs4985155","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.66,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.018,"unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[37,"rs11882123",19,19446936,"rs769267","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs769267-?","rs769267",0,769267,"synonymous_variant",0,"NR",{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.0434,"[0.027-0.06] unit increase","Illumina [at least 560000] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.906,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.028,"[0.017-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[3,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.066,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(East Asian)",0.169,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs562338",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,null,0.022,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.906,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(East Asian)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","HDL cholesterol levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","8p21.3","LPL, RPL30P9","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(Japanese)",0.24,"[0.15-0.33] unit increase","Illumina [1294241]","N"]
[18,"rs2954021",8,126477978,"rs2001945","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist-to-hip ratio adjusted for BMI in non-smokers","75,379 European ancestry women, 45,811 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men","16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men","8q24.13","TRIB1","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-G","rs2001945",0,2001945,"intergenic_variant",1,0.46,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(AA, women)",0.014,"[0.0081-0.0199] unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.596,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(Hispanic)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4963452",11,61815803,"rs4963452","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.3","INCENP","AP003733.1 - AP003733.2","ENSG00000244176","ENSG00000254424",null,35729,24551,"rs4963452-T","rs4963452",0,4963452,"regulatory_region_variant",1,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,null,0.02,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[25,"rs673335",11,75455021,"rs499974","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q13.5","NR","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1550,14479,"rs499974-C","rs499974",0,499974,"regulatory_region_variant",1,0.832,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs673335",11,75455373,"rs600518","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q13.5","NR","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1902,14127,"rs600518-A","rs600518",0,600518,"regulatory_region_variant",1,0.832,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15129459,"rs4985155","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.665,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA, men)",0.021,"[0.013-0.029] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[37,"rs58542926",19,19720399,"rs57504626","2017-09-21",28736931,"Rotroff DM","2017-07-24","Clin Pharmacol Ther","www.ncbi.nlm.nih.gov/pubmed/28736931","Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.","Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes","781 European ancestry individuals, 138 African American ancestry individuals, 345 unknown ancestry individuals",null,"19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs57504626-?","rs57504626",0,57504626,"intron_variant",0,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",0.014,"unit decrease","Affymetrix, Illumina [8129838] (imputed)","N"]
[2,"rs638714",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.656,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.66,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63128081,"rs1168103","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","1p31.3","DOCK7, ATG4C, USP1","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168103-T","rs1168103",0,1168103,"intron_variant",0,"NR",{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,4.968,"[NR] Z score decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.161,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.101,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.502,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.647,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,64963449,"rs4379723","2013-03-15",23263863,"Li J","2012-12-20","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/23263863","GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.","Platelet count","7,943 African American children, 6,234 European ancestry children","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs4379723-T","rs4379723",0,4379723,"intron_variant",0,"NR",{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,5.4297,"[3.28-7.58] unit decrease","Illumina [544917]","N"]
[21,"rs7924036",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,0.513,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(EA)",0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7924036",10,65318766,"rs10761785","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)","8,631 European ancestry individuals","NA","10q21.3","JMJD1C, NRBF2, REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs10761785-T","rs10761785",0,10761785,"intron_variant",0,0.498,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,0.01,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[23,"rs61896141",11,61595564,"rs968567","2019-01-25",30423114,"Laufer VA","2018-11-13","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30423114","Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.","Rheumatoid arthritis","916 African American cases, 1,392 African American controls,","4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-T","rs968567",0,968567,"5_prime_UTR_variant",0,0.18,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(EA)",0.10388,"[0.063-0.145] unit decrease","Illumina [8380626] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.711,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.564,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(EA)",0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs9303521",17,43805194,"rs9303521","2017-03-20",27629089,"Sailer A","2016-09-14","Neurology","www.ncbi.nlm.nih.gov/pubmed/27629089","A genome-wide association study in multiple system atrophy.","Multiple system atrophy","918 European ancestry cases, 3,864 European ancestry controls","NA","17q21.31","CRHR1, MAPT","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs9303521-G","rs9303521",0,9303521,"intron_variant",0,0.49,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,1.3157895,null,"Illumina [4903804] (imputed)","N"]
[34,"rs16940904",17,44859144,"rs415430","2011-09-14",21812969,"Liu X","2011-08-03","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21812969","Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.","Parkinson's disease","268 Ashkenazi Jewish cases, 178 Ashkenazi Jewish controls","1,782 European ancestry cases, 1,658 European ancestry controls","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs415430-T","rs415430",0,415430,"intron_variant",0,0.786,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,{"$nulls":3},"Illumina [525124]","N"]
[2,"rs638714",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.639,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Hispanic)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.905,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Hispanic)",0.128,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-C","rs2144300",0,2144300,"intron_variant",0,0.4,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,4.25,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[4,"rs11122450",1,230304988,"rs10489615","2017-06-01",28107422,"de Vries PS","2017-01-20","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28107422","Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.","Fibrinogen levels","91,953 European ancestry individuals (imputed to HapMap)",null,"1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs10489615-?","rs10489615",0,10489615,"intron_variant",0,"NR",{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,0.0052,"unit increase","Affymetrix, Illumina [2749429] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,0.055,"[0.033-0.077] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-11-25",26833098,"Kilpelainen TO","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833098","Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.","circulating leptin levels","14,586 European ancestry men, 20,706 European ancestry women","8,554 European ancestry men, 8,337 European ancestry women","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,0.61,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(women)",0.033,"[0.019-0.047] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[15,"rs62466318",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(EA, women)",0.0326,"[0.02-0.046] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[18,"rs2954021",8,126486409,"rs17321515","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-A","rs17321515",0,17321515,"intron_variant",0,0.47,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(LDL)",0.07,"mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[21,"rs201220977",10,65104500,"rs7896518","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability","107,207 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-?","rs7896518",0,7896518,"intron_variant",0,"NR",{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,4.926,"z score decrease","Affymetrix, Illumina [7357080] (imputed)","N"]
[23,"rs11407273",11,61640379,"rs174449","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,5553,612,"rs174449-A","rs174449",0,174449,"intergenic_variant",1,0.6452,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Cis/trans-18:2, EA)",0.0021,"[0.0013-0.0029] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs72789541",16,15129970,"rs7200543","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs7200543-A","rs7200543",0,7200543,"synonymous_variant",0,"NR",{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,0.013,"[NR] unit increase","Affymetrix [at least 28613428] (imputed)","N"]
[34,"rs2074404",17,44865603,"rs199498","2014-10-21",24511991,"Hill-Burns EM","2014-02-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/24511991","Identification of a novel Parkinson's disease locus via stratified genome-wide association study.","Parkinson's disease","1,565 European ancestry sproadic Parkinson's disease cases, 435 European ancestry familial Parkinson's disease cases, 1,986 European ancestry controls","1,528 European ancestry sporadic Parkinson's disease cases, 707 European ancestry familial Parkinson's disease cases, 796 European ancestry controls","17q21.31","MAPT","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199498-T","rs199498",0,199498,"intron_variant",0,0.764,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Familial)",1.69,"[1.57-1.81]","Illumina [811597]","N"]
[2,"rs638714",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.66,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(Hispanic)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11102967",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.091,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(East Asian)",0.146,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Valine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,0.05,"[0.024-0.076] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[17,"rs117026536",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.934,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(AA)",0.225,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126478450,"rs2001846","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","8q24.13","TRIB1","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27803,731,"rs2001846-T","rs2001846",0,2001846,"intergenic_variant",1,0.49,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,1.05,"[1.03-1.07]","Affymetrix, Illumina [8600000] (imputed)","N"]
[34,"rs16940904",17,44301840,"rs142920272","2019-04-10",30804558,"Grove J","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804558","Identification of common genetic risk variants for autism spectrum disorder.","Autism spectrum disorder","18,381 European ancestry cases, 27,969 European ancestry controls","2,119 European ancestry cases, 142,379 European ancestry controls","17q21.31","Intergenic","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs142920272-C","rs142920272",1,2532407,"intron_variant",0,0.187,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,1.0881393,"[NR]","Illumina [9112387] (imputed)","N"]
[3,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.933,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.162,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.068,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2012-08-20",22747683,"Eriksson N","2012-06-30","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/22747683","Genetic variants associated with breast size also influence breast cancer risk.","Breast size","16,175 European ancestry female individuals","NA","2p23.3","SLC4A1AP, GCKR","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-T","rs4665972",0,4665972,"intron_variant",0,0.448,{"v":1e-06,"d":"1.00E-06"},6,null,0.08,"[0.047-0.113] cup size increase","Illumina [7422970] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(Indian)",null,null,"Illumina [551825]","N"]
[6,"rs1260326",2,27742603,"rs780093","2015-09-22",25524916,"Palmer ND","2014-12-18","Diabetes","www.ncbi.nlm.nih.gov/pubmed/25524916","Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.","Glucose homeostasis traits","up to 4,176 Mexican American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-?","rs780093",0,780093,"intron_variant",0,null,{"v":1e-06,"d":"1.00E-06"},6,"(SG)",0.14,"[0.081-0.199] unit increase","Illumina [693128]","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-11-25",26833098,"Kilpelainen TO","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833098","Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.","circulating leptin levels adjusted for BMI","up to 14,094 European ancestry men, up to 19,893 European ancestry women","up to 9,076 European ancestry men, up to 9,150 European ancestry women","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,0.61,{"v":1e-06,"d":"1.00E-06"},6,"(women)",0.025,"[0.015-0.035] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs4665985",2,27753878,"rs4665985","2017-08-03",28485404,"Jorgenson E","2017-05-09","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28485404","Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.","Alcohol consumption (drinks per week)","23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.          ","NA","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,7327,6375,"rs4665985-C","rs4665985",0,4665985,"intergenic_variant",1,0.28,{"v":1e-06,"d":"1.00E-06"},6,"(EA, adjusted for lean body mass)",0.04,"[0.02-0.05] drinks per week increase","Affymetrix [NR] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-C","rs7570971",0,7570971,"intron_variant",0,0.627,{"v":1e-06,"d":"1.00E-06"},6,null,0.016,"[0.0099-0.0229] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[7,"rs11399929",2,136506927,"rs6430585","2011-11-04",21979947,"Li X","2011-10-06","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21979947","A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries.","Corneal structure","222 European ancestry cases, 3,324 European ancestry controls","304 European ancestry cases, 518 European ancestry controls, 146 European ancestry cases and 161 European ancestry controls from 70 families","2q21.3","UBXD2","UBXN4",null,null,"ENSG00000144224",null,null,"rs6430585-?","rs6430585",0,6430585,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,1.39,null,"Illumina [~ 290000]","N"]
[15,"rs33951980",7,72856269,"rs2240466","2011-05-26",21490707,"Cornelis MC","2011-04-07","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21490707","Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.","Caffeine consumption","47,431 European ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2240466-A","rs2240466",0,2240466,"3_prime_UTR_variant",0,0.12,{"v":1e-06,"d":"1.00E-06"},6,null,0.1109,"[0.07-0.15] mg/day increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.168,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-A","rs2126259",0,2126259,"intron_variant",0,0.39,{"v":1e-06,"d":"1.00E-06"},6,null,0.11,"[0.071-0.149] unit decrease","Illumina [1361436] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.597,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.598,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-06,"d":"1.00E-06"},6,null,0.0395,"[0.024-0.055] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",0.0395,"[0.024-0.055] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[21,"rs7924036",10,64927823,"rs1935","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals","132,177 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs1935-C","rs1935",0,1935,"missense_variant",0,0.5168,{"v":1e-06,"d":"1.00E-06"},6,null,0.011,"[0.0065-0.0155] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[21,"rs7924036",10,65133822,"rs7923609","2015-05-08",25201988,"Rietveld CA","2014-09-08","Proc Natl Acad Sci U S A","www.ncbi.nlm.nih.gov/pubmed/25201988","Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.","Educational attainment","106,736 European ancestry individuals","NA","10q21.3","JMJD1C, REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7923609-A","rs7923609",0,7923609,"intron_variant",0,0.521,{"v":1e-06,"d":"1.00E-06"},6,null,0.021,"[NR] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[29,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.588,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.588,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261341",15,58738423,"rs12914626","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs12914626-C","rs12914626",0,12914626,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,1.0526316,"[NR]","Illumina [7158791] (imputed)","N"]
[31,"rs3764261",16,56989590,"rs247616","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.678,{"v":1e-06,"d":"1.00E-06"},6,null,1.04,"[1.03-1.06]","Affymetrix [9149595] (imputed)","N"]
[31,"rs3764261",16,56991363,"rs183130","2018-10-24",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","188,577 European and other ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,12588,4399,"rs183130-?","rs183130",0,183130,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(Yoruban)",null,null,"Illumina [4454201] (imputed)","N"]
[31,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.983,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.281,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44828931,"rs199533","2010-09-22",20711177,"Hamza TH","2010-08-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20711177","Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.","Parkinson's disease","2,000 European ancestry cases, 1,986 European ancestry controls","Up to 1,447 cases, 1,468 controls","17q21.31","MAPT","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199533-C","rs199533",0,199533,"synonymous_variant",0,0.78,{"v":1e-06,"d":"1.00E-06"},6,null,1.35,"[1.19-1.52]","Illumina [811597]","N"]
[34,"rs2074404",17,44865439,"rs2074404","2010-03-29",20190752,"Dubois PC","2010-02-28","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20190752","Multiple common variants for celiac disease influencing immune gene expression.","Celiac disease","4,533 European ancestry cases, 10,750 European ancestry controls","4,918 European ancestry cases, 5,684 European ancestry controls","17q21.31","intergenic","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs2074404-?","rs2074404",0,2074404,"intron_variant",0,0.75,{"v":1e-06,"d":"1.00E-06"},6,null,1.11,"[1.06-1.16]","Illumina [292387]","N"]
[35,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,0.675,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",0.019,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.986,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.34,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.938,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.139,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.655,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.634,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.187,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Asian initial, BMI unadjusted)",0.0494,"[0.029-0.07] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[3,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.933,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.16,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.069,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-12-01",26818947,"Imamura M","2016-01-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26818947","Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.","Type 2 diabetes","15,463 Japanese ancestry cases, 26,183 Japanese ancestry controls","20,490 East Asian ancestry cases, 22,922 East Asian ancestry controls, 38,947 European ancestry cases, 121,903 European ancestry controls, 10,587 South Asian ancestry cases, 14,378 South Asian ancestry controls, 3,848 Mexican/Latino cases, 4,366 Mexican/Latino controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Japanese)",1.0758183,"[1.04425991211509-1.10832920480705]","Illumina [7521072] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-C","rs7570971",0,7570971,"intron_variant",0,0.64,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA)",0.017,"[0.0098-0.0232] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[7,"rs11681659",2,136092061,"rs1561277","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","2q21.3","ZRANB3","ZRANB3",null,null,"ENSG00000121988",null,null,"rs1561277-A","rs1561277",0,1561277,"intron_variant",0,0.3354,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA,women)",0.0254,"[0.015-0.036] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","MCM6","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.646,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.016,"[0.0094-0.0224] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[11,"rs59136961",6,34603646,"rs2492863","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (arm fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p21.31","C6orf106, SNRPC, UHRF1BP1","C6orf106",null,null,"ENSG00000196821",null,null,"rs2492863-A","rs2492863",0,2492863,"intron_variant",0,0.139616,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.01842,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[11,"rs59136961",6,34769765,"rs4472337","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","6p21.31","ANKS1A","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs4472337-T","rs4472337",0,4472337,"intron_variant",0,0.155,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.06,"[1.03-1.08]","Affymetrix [9149595] (imputed)","N"]
[11,"rs59136961",6,34827085,"rs9469913","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469913-?","rs9469913",0,9469913,"missense_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[15,"rs62466318",7,72885810,"rs6976930","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-?","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[15,"rs138574868",7,72987354,"rs2286276","2013-08-01",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","Hypertriglyceridemia","1,122 Mexican ancestry cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry cases, 1,054 Mexican ancestry controls","7q11.23","TBL2, VPS37D, MLXIPL, BAZ1B, BCL7B","TBL2",null,null,"ENSG00000106638",null,null,"rs2286276-?","rs2286276",0,2286276,"non_coding_transcript_exon_variant",0,0.88,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.39,"[1.25-1.53]","Illumina [1361436] (imputed)","N"]
[16,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.163,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.096,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.092,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,3.7,"[2.19-5.21] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[18,"rs2954021",8,126477978,"rs2001945","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)","95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","8q24.13","TRIB1","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-G","rs2001945",0,2001945,"intergenic_variant",1,0.484,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(women)",null,null,"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.689,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[21,"rs201220977",10,65027610,"rs10761731","2014-03-25",24026423,"Shameer K","2013-09-12","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/24026423","A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.","Platelet count","13,582 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-A","rs10761731",0,10761731,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,3.81,"[NR] unit decrease","Illumina [476395]","N"]
[23,"rs11407273",11,61639573,"rs174448","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,0.6472,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Cis/trans-18:2, EA)",2E-3,"[0.0012-0.0028] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[29,"rs12900738",15,58635583,"rs4775031","2012-11-13",20125193,"Cirulli ET","2010-02-03","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/20125193","Common genetic variation and performance on standardized cognitive tests.","Cognitive performance","Up to 813 European ancestry individuals, up to 167 East Asian ancestry individuals, up to 7 Hispanic/Latin American individuals, up to 74 South Asian ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775031-?","rs4775031",0,4775031,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(TrailsB)",null,null,"Illumina [up to 563855]","N"]
[29,"rs17301739",15,58730639,"rs17301739","2013-06-26",23535033,"Sherva R","2013-03-24","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/23535033","Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.","Alzheimer's disease (cognitive decline)","303 European ancestry cases",null,"15q21.3","LIPC","LIPC-AS1, LIPC, ALDH1A2",null,null,"ENSG00000259293, ENSG00000166035, ENSG00000128918",null,null,"rs17301739-?","rs17301739",0,17301739,"intron_variant",0,0.07,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.28,"unit decrease","Illumina [NR] (imputed)","N"]
[30,"rs72789541",16,15129459,"rs4985155","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.662,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.015,"[0.0089-0.0211] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[30,"rs3198697",16,15129940,"rs3198697","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-C","rs3198697",0,3198697,"missense_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.017,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.69,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs2074404",17,44865603,"rs199498","2014-10-21",24511991,"Hill-Burns EM","2014-02-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/24511991","Identification of a novel Parkinson's disease locus via stratified genome-wide association study.","Parkinson's disease","1,565 European ancestry sproadic Parkinson's disease cases, 435 European ancestry familial Parkinson's disease cases, 1,986 European ancestry controls","1,528 European ancestry sporadic Parkinson's disease cases, 707 European ancestry familial Parkinson's disease cases, 796 European ancestry controls","17q21.31","MAPT","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199498-T","rs199498",0,199498,"intron_variant",0,0.764,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.35,"[1.25-1.45]","Illumina [811597]","N"]
[35,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.137,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.017,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs6417108",18,47328029,"rs617619","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","18q21.1","NR","ACAA2, AC090227.1",null,null,"ENSG00000167315, ENSG00000266997",null,null,"rs617619-?","rs617619",0,617619,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"Affymetrix [NR]","N"]
[36,"rs151113958",19,11202306,"rs6511720","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.083,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,3.75,"[2.20-5.30] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.881,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.0165,"[0.0096-0.0234] unit increase","Affymetrix [11535925] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.986,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.33,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11202306,"rs6511720","2019-04-30",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Total cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Indian)",null,null,"Illumina [551825]","N"]
[38,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.99,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.439,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.371,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.067,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs11122450",1,230294916,"rs2144300","2013-09-10",23620142,"Reiner AP","2013-04-24","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/23620142","Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.","Circulating myeloperoxidase levels (serum)","9,305 European ancestry individuals",null,"1q42.13","GALNT2","GALNT2",null,null,"ENSG00000143641",null,null,"rs2144300-C","rs2144300",0,2144300,"intron_variant",0,0.39,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.05,"[0.030-0.070] unit decrease","Affymetrix, Illumina [2397181]","N"]
[5,"rs562338",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-03-31",27702941,"Cornelis MC","2016-10-03","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/27702941","Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.","Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio)","5,323 European ancestry individuals","824 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,4.69,"Z-score decrease","Illumina [~ 31000000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Palmitic acid (16:0) levels","8,961 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1261,"unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference adjusted for BMI","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.8425,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0298,"[0.017-0.042] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[11,"rs59136961",6,34827085,"rs9469913","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women","up to 62,368 European ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469913-A","rs9469913",0,9469913,"missense_variant",0,0.8474,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0251,"[0.015-0.036] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[15,"rs33951980",7,72864869,"rs714052","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-?","rs714052",0,714052,"intron_variant",0,0.87,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,2.27,"[1.61-3.23]","Affymetrix [~ 2100000] (imputed)","N"]
[15,"rs62466318",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0351,"[0.02-0.05] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[15,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.905,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.902,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.05,"[1.03-1.08]","Affymetrix, Illumina [247470]","N"]
[17,"rs117026536",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.902,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.05,"[1.03-1.07]","Affymetrix, Illumina [247470]","N"]
[17,"rs117026536",8,19833156,"rs80073370","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Pulse pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8p21.3","LPL, SLC18A1","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,8386,103469,"rs80073370-A","rs80073370",0,80073370,"regulatory_region_variant",1,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.219,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[18,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.045,"[0.025-0.065] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.551395,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.04,"[1.03- 1.06]","Affymetrix, Illumina [8600000] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs35309034",8,126498828,"rs4870941","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-?","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(male)",0.1938,"[0.11-0.28] unit decrease","Affymetrix [7794483] (imputed)","N"]
[18,"rs35309034",8,126504726,"rs6987702","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6987702-G","rs6987702",0,6987702,"intron_variant",0,0.29,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[21,"rs7924036",10,65318766,"rs10761785","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs10761785-G","rs10761785",0,10761785,"intron_variant",0,0.486,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.019,"[0.011-0.026] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[23,"rs7943992",11,61273700,"rs3802951","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","11q12.2","NR","AP003108.1 - MIR4488","ENSG00000255931","ENSG00000266006",null,6152,2368,"rs3802951-?","rs3802951",0,3802951,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,4.648,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[23,"rs174607",11,61639488,"rs422249","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4662,1503,"rs422249-T","rs422249",0,422249,"regulatory_region_variant",1,0.3218,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Cis/trans-18:2, EA)",0.0021,"[0.0013-0.0029] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[23,"rs2736598",11,61705207,"rs2158027","2019-03-25",30589442,"Whitfield JB","2018-12-27","Alcohol Clin Exp Res","www.ncbi.nlm.nih.gov/pubmed/30589442","Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers.","Gamma glutamyl transferase levels in low alcohol consumption","8,716 individuals","NA","11q12.3","NR","RAB3IL1 - RNU6-1243P","ENSG00000167994","ENSG00000200898",null,17466,159,"rs2158027-?","rs2158027",0,2158027,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0195,"[0.011-0.028] unit decrease","Illumina [~ 7800000] (imputed)","N"]
[23,"rs2727260",11,61712131,"rs2727261","2012-07-27",22675492,"Prescott J","2012-06-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/22675492","Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.","Estradiol levels","1,583 European ancestry female individuals","NA","11q12.3","FTH1, BEST1","RNU6-1243P - BEST1","ENSG00000200898","ENSG00000167995",null,6659,5162,"rs2727261-T","rs2727261",0,2727261,"regulatory_region_variant",1,0.09,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.159,"[NR] unit increase","Illumina [~ 2500000] (imputed)","N"]
[28,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,0.973,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.204,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs28690720",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.888,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.64,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.612,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs60315394",15,58712203,"rs11857380","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs11857380-C","rs11857380",0,11857380,"5_prime_UTR_variant",0,0.131,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Weight )",0.03,"[NR] kg increase","Illumina [899892]","N"]
[29,"rs1077835",15,58723675,"rs1800588","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.41,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.078,"[0.045-0.111] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[30,"rs1684546",16,15587497,"rs34792","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","16p13.11","C16orf45","C16orf45, C16orf45, AC140504.1",null,null,"ENSG00000278823, ENSG00000166780, ENSG00000261130",null,null,"rs34792-C","rs34792",0,34792,"intron_variant",0,0.38,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.21,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.709,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3816117",16,56995236,"rs1800775","2017-11-01",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","Apolipoprotein A1 levels","1,451 European ancestry type 2 diabetes cases and controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.44,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.6,"(% variance) increase","Affymetrix [389878]","N"]
[34,"rs16940904",17,44819565,"rs199443","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199443-T","rs199443",0,199443,"intron_variant",0,0.2,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Ajusted for ApoE)",0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[37,"rs11882123",19,19552413,"rs4808955","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808955-?","rs4808955",0,4808955,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0401,"[0.023-0.057] unit decrease","Illumina [at least 560000] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.12,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63049593,"rs1748195","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Crohn's disease","12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls","NA","1p31.3","ANGPTL3, AL138847.1, DOCK7, USP1","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-?","rs1748195",0,1748195,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [9560910] (imputed)","N"]
[3,"rs629301",1,109818530,"rs646776","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.19,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(chol, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[5,"rs562338",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum total protein level","Up to 25,539 European ancestry individuals, 10,168 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.56,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Japanese)",0.031,"[0.017-0.045] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[10,"rs272863",5,131721204,"rs274557","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","8,631 European ancestry individuals","NA","5q31.1","SLC22A5","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274557-T","rs274557",0,274557,"intron_variant",0,0.599,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.14,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[11,"rs59136961",6,34773727,"rs2395607","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs2395607-T","rs2395607",0,2395607,"intron_variant",0,0.1724,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.0282,"[0.016-0.04] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[19,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs174597",11,61602003,"rs174575","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174575-C","rs174575",0,174575,"intron_variant",0,0.7453,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Cis/trans-18:2, EA)",0.0021,"[0.0011-0.0031] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[29,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.33,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.628,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.104,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.52,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs3198697",16,15129940,"rs3198697","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-C","rs3198697",0,3198697,"missense_variant",0,0.585,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.018,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15138413,"rs3803573","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","16p13.11","NR","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs3803573-?","rs3803573",0,3803573,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(female)",0.12148,"[0.07-0.173] unit decrease","Affymetrix [7794483] (imputed)","N"]
[34,"rs9303521",17,43795433,"rs11655470","2012-05-25",22504419,"Taal HR","2012-04-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22504419","Common variants at 12q15 and 12q24 are associated with infant head circumference.","Head circumference (infant)","10,768 European ancestry infants","8,321 European ancestry infants","17q21.31","MAPT, CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs11655470-T","rs11655470",0,11655470,"intron_variant",0,0.49,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.048,"[0.028-0.068] SD increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[34,"rs9303521",17,43805194,"rs9303521","2009-10-16",19801982,"Rivadeneira F","2009-10-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19801982","Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.","Bone mineral density (hip)","19,195 European ancestry individuals","NA","17q21.31","CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs9303521-T","rs9303521",0,9303521,"intron_variant",0,0.46,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.06,"[0.04-0.07] s.d. decrease","Affymetrix, Illumina [2543686] (imputed)","N"]
[34,"rs16940904",17,44819565,"rs199443","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199443-T","rs199443",0,199443,"intron_variant",0,0.2,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[34,"rs2074404",17,44863133,"rs916888","2017-03-20",27629089,"Sailer A","2016-09-14","Neurology","www.ncbi.nlm.nih.gov/pubmed/27629089","A genome-wide association study in multiple system atrophy.","Multiple system atrophy","918 European ancestry cases, 3,864 European ancestry controls","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs916888-T","rs916888",0,916888,"intron_variant",0,0.75,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,1.35,null,"Illumina [4903804] (imputed)","N"]
[35,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,0.675,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.31,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs151113958",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.308,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs58542926",19,19721722,"rs12610185","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs12610185-A","rs12610185",0,12610185,"intron_variant",0,0.053,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(TG )",0.03,"[NR] mg/dL increase","Illumina [899892]","N"]
[38,"rs7412",19,45415640,"rs445925","2011-10-07",21909108,"Bis JC","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909108","Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.","Carotid intima media thickness","Up to 31,211 European ancestry individuals","10,553 European ancestry individuals, 687 Orcadian individuals","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-G","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.89,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(plaque)",1.22,"[1.12-1.32]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(mass)",5.3E-3,"[-0.00215-0.01275] ng/ml decrease","Illumina [796174]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.012,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Urate levels","8,868 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.57,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.069,"[0.040,0.098] unit increase","Illumina [561583]","N"]
[6,"rs1260326",2,27742603,"rs780093","2012-08-20",22747683,"Eriksson N","2012-06-30","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/22747683","Genetic variants associated with breast size also influence breast cancer risk.","Breast size","16,175 European ancestry female individuals","NA","2p23.3","SLC4A1AP","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.416,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.072,"[0.041-0.103] cup size increase","Illumina [7422970] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","MCM6","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.66,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.016,"[0.0091-0.0225] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA, women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[19,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[25,"rs673335",11,75455309,"rs600626","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)","8,631 European ancestry individuals","NA","11q13.5","MOGAT2","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1838,14191,"rs600626-A","rs600626",0,600626,"regulatory_region_variant",1,0.827,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.07,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[28,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,0.974,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.198,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.596,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15129459,"rs4985155","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.664,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.015,"[0.0084-0.0214] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[31,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.02,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,43824360,"rs7207400","2016-02-03",25778476,"Jun G","2015-03-17","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25778476","A novel Alzheimer disease locus located near the gene encoding tau protein.","Alzheimer's disease in APOE e4- carriers","7,184 cases, 26,968 controls","718 European ancestry cases, 1,699 European ancestry controls","17q21.31","CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs7207400-T","rs7207400",0,7207400,"intron_variant",0,0.75,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.1363636,"[1.08-1.2]","NR [NR]","N"]
[34,"rs2074404",17,44863133,"rs916888","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs916888-T","rs916888",0,916888,"intron_variant",0,0.763,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.051,"NR unit increase","Illumina [NR] (imputed)","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.914,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.027,"[0.015-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.065,"[0.038-0.092] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.59,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.05,"[0.028-0.072] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[11,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.844,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA, women)",0.0278,"[0.016-0.04] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[19,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs7102974",11,61560035,"rs7102974","2018-03-05",29367611,"Gao B","2018-01-24","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29367611","Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.","Carboplatin disposition in epthelial ovarian cancer","42 European ancestry cases, 14 Asian ancestry cases","NA","11q12.2","C11orf10","TMEM258",null,null,"ENSG00000134825",null,null,"rs7102974-?","rs7102974",0,7102974,"5_prime_UTR_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(adjusted for dose, GFR & AST)",1.49,"unit decrease (EA)","Illumina [610255]","N"]
[30,"rs72789541",16,15138413,"rs3803573","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","16p13.11","NR","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs3803573-?","rs3803573",0,3803573,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(male)",0.17267,"[0.098-0.247] unit decrease","Affymetrix [7794483] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.794,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Hispanic)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs2074404",17,44865498,"rs199499","2016-02-03",25778476,"Jun G","2015-03-17","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25778476","A novel Alzheimer disease locus located near the gene encoding tau protein.","Alzheimer's disease in APOE e4- carriers","7,184 cases, 26,968 controls","718 European ancestry cases, 1,699 European ancestry controls","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199499-C","rs199499",0,199499,"intron_variant",0,0.81,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.1627907,"[1.09-1.23]","NR [NR]","N"]
[37,"rs61061000",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Systolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.34,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Japanese)",0.3725,"[0.21-0.53] unit increase","Illumina [6200000] (imputed)","N"]
[3,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.078,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.134,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2010-09-21",20705733,"O'Seaghdha CM","2010-08-12","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20705733","Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.","Calcium levels","20,611 European ancestry individuals","NA","2p23.3","FNDC4, IFT172, GCKR, C2orf16","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs77200710",2,27801759,"rs1919128","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919128-G","rs1919128",0,1919128,"missense_variant",0,0.529,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0379,"[0.021-0.054] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.614,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs33924196",8,126507389,"rs2954038","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","8q24.13","NSMCE2, KIAA0196, TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-C","rs2954038",0,2954038,"intron_variant",0,0.32,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Triglyceride, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[27,"rs78689694",11,126244955,"rs4307732","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q24.2","NR","ST3GAL4",null,null,"ENSG00000110080",null,null,"rs4307732-G","rs4307732",0,4307732,"non_coding_transcript_exon_variant",0,0.901,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(EA)",0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.376,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.057,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.815,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs72789541",16,15131974,"rs1136001","2010-03-25",20189936,"Okada Y","2010-02-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20189936","A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.","Height","19,633 Japanese ancestry individuals","NA","16p13.11","PDXDC1, NTAN1","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs1136001-T","rs1136001",0,1136001,"missense_variant",0,0.44,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.05,"[0.03-0.07] cm decrease","Illumina [420885]","N"]
[34,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43567337,"rs1879586","2017-08-03",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Ovarian cancer in BRCA1 mutation carriers","2,933 European ancestry carrier cases, 16,103 European ancestry carrier controls","NA","17q21.31","NR","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs1879586-G","rs1879586",0,1879586,"intron_variant",0,0.181254,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,1.1804551,"[1.0983093028467-1.26874471717965]","Illumina [11595112] (imputed)","N"]
[34,"rs16940904",17,44364209,"rs2732614","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","KIAA1267, LRRC37","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2732614-T","rs2732614",0,2732614,"intron_variant",0,0.2,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Ajusted for ApoE)",0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[35,"rs11662596",18,47121316,"rs17798991","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs17798991-A","rs17798991",0,17798991,"3_prime_UTR_variant",0,0.387,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Light activity )",0.03,"[NR] %awake time increase","Illumina [899892]","N"]
[35,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs638714",1,63118196,"rs10889353","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.32,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.06,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[5,"rs562338",2,21294975,"rs541041","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","2p24.1","FLJ21820, GDF7, APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.16,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(LDL, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[16,"rs9987289",8,9184231,"rs4240624","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-G","rs4240624",0,4240624,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.0869565,"[NR]","Illumina [7158791] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.502,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs112875651",8,126506694,"rs112875651","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8q24.13","TRIB1, LOC100130231","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.11,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[21,"rs7924036",10,65271488,"rs10740131","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma levels","7,701 Finnish ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10740131-T","rs10740131",0,10740131,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.0727,"[0.041-0.104] SD units increase","NR [10700000] (imputed)","N"]
[23,"rs2727263",11,61616012,"rs2851682","2017-02-27",27490719,"Bacelis J","2016-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/27490719","Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways.","Gestational age at birth (child effect)","1,109 Norwegian ancestry children","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2851682-G","rs2851682",0,2851682,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,{"$nulls":3},"NR [525577]","N"]
[24,"rs648336",11,68601974,"rs597539","2018-01-19",29221444,"Divers J","2017-12-08","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/29221444","Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.","Coronary artery calcified atherosclerotic plaque score in type 2 diabetes","691 African American individuals","205 African American individuals","11q13.3","CPT1A","CPT1A",null,null,"ENSG00000110090",null,null,"rs597539-?","rs597539",0,597539,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.948,"[0.74-3.16] unit decrease","Illumina [at least 13000000] (imputed)","N"]
[29,"rs261291",15,58683366,"rs1532085","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.403,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(Filipino)",1.634,"[1.56-1.70] unit decrease","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[29,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.358,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs16940904",17,44364209,"rs2732614","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","KIAA1267, LRRC37","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2732614-T","rs2732614",0,2732614,"intron_variant",0,0.2,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[36,"rs2278426",19,11330942,"rs17699030","2012-11-02",20889312,"Wang KS","2010-10-01","Schizophr Res","www.ncbi.nlm.nih.gov/pubmed/20889312","A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.","Bipolar disorder and schizophrenia","651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs17699030-?","rs17699030",0,17699030,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7062,"[NR]","Affymetrix [722112]","N"]
[37,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[1,"rs11591147",1,55505647,"rs11591147","2018-05-11",29436472,"Casalone E","2018-02-07","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/29436472","A novel variant in GLIS3 is associated with osteoarthritis.","Osteoarthritis of the knee (with total joint replacement)","2,188 European ancestry cases, 9,939 European ancestry healthy controls","2,281 European ancestry cases, 9,194 European ancestry healthy controls","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.017137,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,1.56,"[1.25-1.95]","Illumina [270934]","N"]
[2,"rs638714",1,62912919,"rs10158897","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","1p31.3","USP1","USP1",null,null,"ENSG00000162607",null,null,"rs10158897-T","rs10158897",0,10158897,"intron_variant",0,0.2,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(LDL)",0.021,"mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[5,"rs562338",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.021,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs67798437",2,27801418,"rs1919126","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919126-C","rs1919126",0,1919126,"missense_variant",0,null,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.20432469,"[0.11-0.29] unit decrease","Illumina [247039]","N"]
[11,"rs59136961",6,34552797,"rs2814944","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6p21.31","NR","AL031577.1 - C6orf106","ENSG00000196114","ENSG00000196821",null,8364,2268,"rs2814944-G","rs2814944",0,2814944,"intergenic_variant",1,0.844,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs117026536",8,19844222,"rs12678919","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.18,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(HDL)",0.125,"[0.070-0.180] unit increase","Illumina [561583]","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs9939224",16,57006590,"rs7499892","2009-03-31",19260141,"Zemunik T","2009-02-01","Croat Med J","www.ncbi.nlm.nih.gov/pubmed/19260141","Genome-wide association study of biochemical traits in Korcula Island, Croatia.","Biochemical measures","898 Korculan (founder/genetic isolate) individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-A","rs7499892",0,7499892,"intron_variant",0,0.16,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(HDL cholesterol)",0.24,"[0.14-0.34] mmol/L decrease","Illumina [316730]","N"]
[37,"rs11085253",19,19276359,"rs7249142","2013-06-14",23382691,"Lauc G","2013-01-31","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23382691","Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.","IgG glycosylation","2,247 European ancestry individuals","NA","19p13.11","NR","MEF2B, BORCS8-MEF2B",null,null,"ENSG00000213999, ENSG00000064489",null,null,"rs7249142-G","rs7249142",0,7249142,"intron_variant",0,0.619273395452519,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(IGP30)",0.1523,"[0.085-0.219] unit increase","Illumina [~ 2500000] (imputed)","N"]
[31,"rs3764261",16,56985514,"rs72786786","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6739,10248,"rs72786786-A","rs72786786",0,72786786,"regulatory_region_variant",1,0.3106,"1E-500",500,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs41290120",19,45382675,"rs41290120","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs41290120-A","rs41290120",0,41290120,"intron_variant",0,0.0416,"1E-500",500,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,"1E-769",769,null,0.241,"[NR] unit increase","NR [NR] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,"3E-484",483.52287874528,"(Vacuolar protein sorting-associated protein 29, VPS29.14318.1.3)",1.69,"[1.61-1.77] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs7412",19,45413233,"rs1065853","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-G","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.93,"5E-324",323.301029995663,null,0.603,"[0.58-0.63] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[31,"rs3764261",16,56994528,"rs17231506","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-T","rs17231506",0,17231506,"regulatory_region_variant",1,0.31,"7E-316",315.154901959985,null,0.243,"[0.23-0.25] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[38,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,"7E-370",369.154901959985,"(Valine--tRNA ligase, VARS.13083.18.3)",0.87,"[0.83-0.91] unit increase","Affymetrix [10572788] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,"7E-380",379.154901959985,null,3.39,"[3.21-3.57] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs7412",19,45412079,"rs7412","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.066,"8E-315",314.096910013008,"(Trans-ethnic initial)",0.374,"[0.36-0.39] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs3764261",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.294,"9E-311",310.04575749056,"(Trans-ethnic initial)",0.241,"[0.23-0.25] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]

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["GenomicLocus","IndSigSNP","chr","bp","snp","DateAddedToCatalog","PMID","FirstAuth","Date","Journal","Link","Study","Trait","InitialN","ReplicationN","Region","ReportedGene","MappedGene","UpGene","DownGene","SNP_Gene_ID","UpGeneDist","DownGeneDist","Strongest","SNPs","marged","SNP_ID_cur","Context","intergenic","RiskAF","P","Pmlog","Ptext","OrBeta","95CI","Platform","CNV"]
[4,"rs629301",1,109817192,"rs7528419","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7782,{"v":0,"d":"0.00E+00"},308.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":1E-305,"d":"1.00E-305"},305,null,0.229,"[0.22-0.24] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7715,{"v":1E-300,"d":"1.00E-300"},300,null,0.1364,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.379,{"v":1E-300,"d":"1.00E-300"},300,null,0.1118,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19830170,"rs1569209","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,5400,106455,"rs1569209-T","rs1569209",0,1569209,"regulatory_region_variant",1,0.9206,{"v":1E-300,"d":"1.00E-300"},300,null,0.2112,"[0.2-0.22] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs2266788",11,116586283,"rs7350481","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-T","rs7350481",0,7350481,"regulatory_region_variant",1,0.0708,{"v":1E-300,"d":"1.00E-300"},300,null,0.2272,"[0.22-0.24] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.251,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.25,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs139857231",11,117002403,"rs6589598","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","PCSK7","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,12506,3841,"rs6589598-G","rs6589598",0,6589598,"intergenic_variant",1,0.778,{"v":1E-300,"d":"1.00E-300"},300,"(PCSK7)",1.043,"[1-1.09] unit increase","Illumina [> 1000000] (imputed)","N"]
[34,"rs142158911",19,11187324,"rs143020224","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs143020224-C","rs143020224",0,143020224,"intron_variant",0,0.8693,{"v":1E-300,"d":"1.00E-300"},300,null,0.1619,"[0.15-0.17] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[27,"rs7970695",12,121424861,"rs7310409","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.39,{"v":3e-299,"d":"3.00E-299"},298.52287874528,null,0.137,"[0.13-0.14] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-297,"d":"3.00E-297"},296.52287874528,null,0.14,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19850099,"rs79407615","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,25329,86526,"rs79407615-T","rs79407615",0,79407615,"intergenic_variant",1,0.9025,{"v":3e-293,"d":"3.00E-293"},292.52287874528,null,0.1799,"[0.17-0.19] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":4E-289,"d":"4.00E-289"},288.397940008672,"(Trans-ethnic initial)",0.16,"[0.15-0.17] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":6e-289,"d":"6.00E-289"},288.221848749616,null,0.247,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65066186,"rs10761741","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean platelet volume","164,454 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.4182,{"v":5e-287,"d":"5.00E-287"},286.301029995663,null,0.1326053,"[0.13-0.14] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":7E-287,"d":"7.00E-287"},286.154901959985,null,0.246,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs56393506",6,161089307,"rs56393506","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,null,{"v":8e-285,"d":"8.00E-285"},284.096910013008,null,13.6,"[12.78-14.42] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":6e-284,"d":"6.00E-284"},283.221848749616,null,0.239,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-283,"d":"1.00E-283"},283,{"$nulls":3},"NR [2501749] (imputed)","N"]
[34,"rs142158911",19,11196886,"rs8106503","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,6784,3152,"rs8106503-T","rs8106503",0,8106503,"intergenic_variant",1,0.8354,{"v":2E-281,"d":"2.00E-281"},280.698970004336,null,0.1334,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-272,"d":"2.00E-272"},271.698970004336,"(EA)",0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131785684,"rs12515180","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","5q31.1",null,"AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs12515180-?","rs12515180",0,12515180,"intron_variant",0,"NR",{"v":1e-271,"d":"1.00E-271"},271,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs7970695",12,121424861,"rs7310409","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-A","rs7310409",0,7310409,"intron_variant",0,0.39,{"v":8e-269,"d":"8.00E-269"},268.096910013008,null,0.147,"[0.14-0.15] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-268,"d":"5.00E-268"},267.301029995663,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":4E-262,"d":"4.00E-262"},261.397940008672,null,0.221,"[NR] unit decrease","NR [NR] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3642,{"v":3e-259,"d":"3.00E-259"},258.52287874528,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0149,{"v":3e-257,"d":"3.00E-257"},256.52287874528,null,0.3952,"[0.37-0.42] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.413,{"v":4e-253,"d":"4.00E-253"},252.397940008672,"(Trans-ethnic initial)",0.115,"[0.11-0.12] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[34,"rs142158911",19,11191197,"rs114846969","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19p13.2","NR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,1095,8841,"rs114846969-A","rs114846969",0,114846969,"intergenic_variant",1,0.1172,{"v":2e-252,"d":"2.00E-252"},251.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-251,"d":"3.00E-251"},250.52287874528,"(EA)",0.141,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":3e-250,"d":"3.00E-250"},249.52287874528,"(EA)",0.169,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3E-249,"d":"3.00E-249"},248.52287874528,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",0.76,"[0.72-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":4e-249,"d":"4.00E-249"},248.397940008672,{"$nulls":3},"NR [2501549] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2E-247,"d":"2.00E-247"},246.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":2e-245,"d":"2.00E-245"},244.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-242,"d":"5.00E-242"},241.301029995663,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":7e-242,"d":"7.00E-242"},241.154901959985,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":5e-241,"d":"5.00E-241"},240.301029995663,null,0.167,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":7e-240,"d":"7.00E-240"},239.154901959985,null,16.95,"[16.01-17.89] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":2e-239,"d":"2.00E-239"},238.698970004336,null,0.115,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":1E-236,"d":"1.00E-236"},236,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,null,{"v":4E-231,"d":"4.00E-231"},230.397940008672,null,64.74,"[62.11-67.37] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1E-230,"d":"1.00E-230"},230,null,0.227,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.232,{"v":4e-230,"d":"4.00E-230"},229.397940008672,"(CUB and zona pellucida-like domain-containing protein 1, CUZD1.7943.16.3)",0.82,"[0.76-0.88] unit decrease","Affymetrix [10572788] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.215441066,{"v":9e-230,"d":"9.00E-230"},229.04575749056,"(GRN)",0.727792,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[5,"rs668948",2,21299867,"rs577584","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,32922,46922,"rs577584-A","rs577584",0,577584,"intergenic_variant",1,0.6896,{"v":1e-229,"d":"1.00E-229"},229,null,0.1008,"[0.095-0.107] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-228,"d":"9.00E-228"},227.04575749056,null,0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-227,"d":"4.00E-227"},226.397940008672,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19819328,"rs325","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs325-T","rs325",0,325,"intron_variant",0,0.9032,{"v":4e-227,"d":"4.00E-227"},226.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":3E-226,"d":"3.00E-226"},225.52287874528,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":7e-224,"d":"7.00E-224"},223.154901959985,null,0.234,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","2q21.3","LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.711,{"v":2e-222,"d":"2.00E-222"},221.698970004336,"(Lactase-phlorizin hydrolase, LCT.9017.58.3)",0.78,"[0.74-0.82] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-G","rs157580",0,157580,"intron_variant",0,0.3949,{"v":8e-220,"d":"8.00E-220"},219.096910013008,null,31.6502,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":2e-219,"d":"2.00E-219"},218.698970004336,null,0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136381348,"rs12465802","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","2q21.3","NR","R3HDM1",null,null,"ENSG00000048991",null,null,"rs12465802-A","rs12465802",0,12465802,"intron_variant",0,0.282,{"v":3e-218,"d":"3.00E-218"},217.52287874528,"(Lactase-phlorizin hydrolase, LCT.9017.58.3)",0.78,"[0.74-0.82] unit decrease","Affymetrix [10572788] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.879,{"v":5e-217,"d":"5.00E-217"},216.301029995663,"(Trans-ethnic initial)",0.17,"[0.16-0.18] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.367,{"v":1e-213,"d":"1.00E-213"},213,"(Trans-ethnic initial)",0.107,"[0.1-0.11] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.28,{"v":4e-213,"d":"4.00E-213"},212.397940008672,null,0.081,"[0.075-0.087] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[13,"rs10455872",6,161123451,"rs4252185","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","PLG",null,null,"ENSG00000122194",null,null,"rs4252185-C","rs4252185",0,4252185,"intron_variant",0,null,{"v":5e-211,"d":"5.00E-211"},210.301029995663,null,23.93,"[22.64-25.22] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":8e-211,"d":"8.00E-211"},210.096910013008,"(Granulins, GRN.4992.49.1)",0.83,"[0.77-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","2q21.3","LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-G","rs4988235",0,4988235,"intron_variant",0,0.148,{"v":5e-210,"d":"5.00E-210"},209.301029995663,"(LCT)",0.963,"[0.91-1.02] unit decrease","Illumina [> 1000000] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":2e-208,"d":"2.00E-208"},207.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,null,{"v":2e-207,"d":"2.00E-207"},206.698970004336,null,49.06,"[46.85-51.27] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":1E-206,"d":"1.00E-206"},206,"(EA)",0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(Trans-ethnic initial)",0.128,"[0.12-0.14] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(EA)",0.22,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.228,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":4e-202,"d":"4.00E-202"},201.397940008672,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":5e-202,"d":"5.00E-202"},201.301029995663,null,0.185,"[NR] unit decrease","NR [NR] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":1e-201,"d":"1.00E-201"},201,"(EA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":3E-201,"d":"3.00E-201"},200.52287874528,"(EA)",0.18,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":2E-200,"d":"2.00E-200"},199.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.13,{"v":2E-199,"d":"2.00E-199"},198.698970004336,null,0.17,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,"NR",{"v":3e-199,"d":"3.00E-199"},198.52287874528,null,0.186,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":1E-194,"d":"1.00E-194"},194,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.072,{"v":5e-193,"d":"5.00E-193"},192.301029995663,"(EA)",0.237,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,"NR",{"v":2E-191,"d":"2.00E-191"},190.698970004336,null,0.181,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73025975,"rs13234131","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13234131-A","rs13234131",0,13234131,"intron_variant",0,0.8853,{"v":4e-191,"d":"4.00E-191"},190.397940008672,null,0.1275,"[0.12-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":3e-190,"d":"3.00E-190"},189.52287874528,"(EA)",0.231,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":1e-189,"d":"1.00E-189"},189,"(EA)",0.176,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":1e-188,"d":"1.00E-188"},188,null,0.107,"[NR] unit increase","NR [NR] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":3E-187,"d":"3.00E-187"},186.52287874528,null,0.193,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs58253018",8,126490498,"rs58253018","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs58253018-A","rs58253018",0,58253018,"intron_variant",0,0.3738,{"v":2e-182,"d":"2.00E-182"},181.698970004336,null,0.0984,"[0.092-0.105] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.936,{"v":3e-182,"d":"3.00E-182"},181.52287874528,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":8e-182,"d":"8.00E-182"},181.096910013008,null,0.168,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44773783,"rs199441","2019-02-01",30573740,"Yap CX","2018-12-20","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30573740","Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.","Male-pattern baldness","205,327 European ancestry males","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199441-A","rs199441",0,199441,"intron_variant",0,0.215491,{"v":1E-181,"d":"1.00E-181"},181,null,0.109361,"[0.1-0.12] unit decrease","NR [19129689] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.067,{"v":5e-181,"d":"5.00E-181"},180.301029995663,"(EA)",0.24,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":5e-181,"d":"5.00E-181"},180.301029995663,null,0.19,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422160,"rs12721051","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs12721051-C","rs12721051",0,12721051,"3_prime_UTR_variant",0,0.8427,{"v":1E-179,"d":"1.00E-179"},179,null,0.1061,"[0.099-0.113] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":4e-179,"d":"4.00E-179"},178.397940008672,null,0.171,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":2e-178,"d":"2.00E-178"},177.698970004336,null,0.225,"[NR] unit increase","NR [NR] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,"NR",{"v":1e-177,"d":"1.00E-177"},177,null,0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,"NR",{"v":5E-177,"d":"5.00E-177"},176.301029995663,null,0.115,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.879,{"v":4E-176,"d":"4.00E-176"},175.397940008672,"(Trans-ethnic initial)",0.155,"[0.14-0.17] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":7E-176,"d":"7.00E-176"},175.154901959985,null,0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.015,{"v":8E-175,"d":"8.00E-175"},174.096910013008,null,0.325,"[0.3-0.35] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":1E-173,"d":"1.00E-173"},173,null,0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-171,"d":"2.00E-171"},170.698970004336,{"$nulls":3},"NR [25015711] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":1e-170,"d":"1.00E-170"},170,null,5.65,"[5.24-6.06] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":2E-170,"d":"2.00E-170"},169.698970004336,null,0.134,"[NR] unit decrease","NR [NR] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-170,"d":"4.00E-170"},169.397940008672,{"$nulls":3},"NR [2501749] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2e-168,"d":"2.00E-168"},167.698970004336,null,0.148,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":4E-167,"d":"4.00E-167"},166.397940008672,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":2e-164,"d":"2.00E-164"},163.698970004336,"(EA)",0.199,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-164,"d":"2.00E-164"},163.698970004336,{"$nulls":3},"NR [2501543] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":3e-164,"d":"3.00E-164"},163.52287874528,null,0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-164,"d":"4.00E-164"},163.397940008672,null,0.144,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.897,{"v":9e-164,"d":"9.00E-164"},163.04575749056,"(EA)",0.184,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,null,{"v":4e-163,"d":"4.00E-163"},162.397940008672,null,16.77,"[15.63-17.91] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":6e-163,"d":"6.00E-163"},162.221848749616,null,0.163,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,"NR",{"v":7e-163,"d":"7.00E-163"},162.154901959985,null,0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":3E-162,"d":"3.00E-162"},161.52287874528,null,0.161,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.897,{"v":4e-162,"d":"4.00E-162"},161.397940008672,"(EA)",0.184,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,"NR",{"v":4e-161,"d":"4.00E-161"},160.397940008672,null,0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3798,{"v":3E-160,"d":"3.00E-160"},159.52287874528,null,0.0748,"[0.069-0.08] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":9e-160,"d":"9.00E-160"},159.04575749056,"(EA)",0.191,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":4E-159,"d":"4.00E-159"},158.397940008672,"(Protein CEI, C5orf38.6378.2.3)",0.82,"[0.76-0.88] unit increase","Affymetrix [10572788] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2e-158,"d":"2.00E-158"},157.698970004336,"(EA)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0194,{"v":6E-158,"d":"6.00E-158"},157.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[18,"rs76722925",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.896,{"v":9E-158,"d":"9.00E-158"},157.04575749056,"(EA)",0.182,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","11q23.3","APO-cluster","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":2e-157,"d":"2.00E-157"},156.698970004336,null,0.244,"[0.23-0.26] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":2e-157,"d":"2.00E-157"},156.698970004336,"(EA)",0.174,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-157,"d":"3.00E-157"},156.52287874528,null,0.194,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21291312,"rs548145","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24367,55477,"rs548145-T","rs548145",0,548145,"intergenic_variant",1,0.2416,{"v":6e-156,"d":"6.00E-156"},155.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.6,{"v":9e-155,"d":"9.00E-155"},154.04575749056,"(Triglycerides in very large HDL)",0.26,"[0.24-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[18,"rs7819706",8,19824563,"rs1059611","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs1059611-?","rs1059611",0,1059611,"3_prime_UTR_variant",0,"NR",{"v":1e-154,"d":"1.00E-154"},154,null,0.1698,"[0.16-0.18] unit decrease novel","Illumina [6108953] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.069,{"v":3e-154,"d":"3.00E-154"},153.52287874528,null,0.337,"[0.31-0.36] unit increase","Affymetrix [7947838] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.0686,{"v":3e-154,"d":"3.00E-154"},153.52287874528,null,0.3368,"[0.31-0.36] unit increase","NR [8041861] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-154,"d":"4.00E-154"},153.397940008672,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-154,"d":"9.00E-154"},153.04575749056,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.0693,{"v":1E-153,"d":"1.00E-153"},153,null,0.3122,"[0.29-0.34] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.879,{"v":1e-152,"d":"1.00E-152"},152,"(EA)",0.168,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-151,"d":"4.00E-151"},150.397940008672,{"$nulls":3},"NR [25015711] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.13,{"v":1e-149,"d":"1.00E-149"},149,null,0.155,"[NR] unit increase","NR [NR] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.346,{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":1e-149,"d":"1.00E-149"},149,null,0.197,"[NR] unit increase","NR [NR] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2012-08-14",22832961,"Kamboh MI","2012-05-15","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/22832961","Genome-wide association study of Alzheimer's disease.","Alzheimer's disease","1,291 European ancestry cases, 938 European ancestry controls","509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls","19q13.32","APOE, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-149,"d":"8.00E-149"},148.096910013008,null,3.45,"[NR]","Illumina [2543888] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3E-148,"d":"3.00E-148"},147.52287874528,"(glucose/mannose)",0.041,"[0.037-0.045] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":4e-148,"d":"4.00E-148"},147.397940008672,"(Cardiotrophin-1, CTF1.13732.79.3)",0.8,"[0.74-0.86] unit increase","Affymetrix [10572788] (imputed)","N"]
[19,"rs33924196",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7181,{"v":7e-148,"d":"7.00E-148"},147.154901959985,null,0.0776,"[0.072-0.083] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.892,{"v":2e-147,"d":"2.00E-147"},146.698970004336,"(EA)",0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.7,{"v":9e-147,"d":"9.00E-147"},146.04575749056,"(EA)",0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":9e-147,"d":"9.00E-147"},146.04575749056,null,7.14,"[6.57-7.71] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":1E-146,"d":"1.00E-146"},146,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.7,{"v":1E-146,"d":"1.00E-146"},146,"(EA)",0.115,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-145,"d":"1.00E-145"},145,null,0.167,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2e-145,"d":"2.00E-145"},144.698970004336,null,0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.8416,{"v":1E-142,"d":"1.00E-142"},142,null,0.093,"[0.086-0.1] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":2e-142,"d":"2.00E-142"},141.698970004336,null,0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":7e-142,"d":"7.00E-142"},141.154901959985,null,0.25,"[0.23-0.27] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[30,"rs1077835",15,58723939,"rs2070895","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":1e-140,"d":"1.00E-140"},140,null,0.1322,"[0.12-0.14] unit increase novel","Illumina [6108953] (imputed)","N"]
[5,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-140,"d":"4.00E-140"},139.397940008672,null,0.139,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,"NR",{"v":1E-139,"d":"1.00E-139"},139,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,"NR",{"v":3e-139,"d":"3.00E-139"},138.52287874528,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":9e-139,"d":"9.00E-139"},138.04575749056,null,0.236,"[0.22-0.26] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73001021,"rs35173225","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,7900,6503,"rs35173225-T","rs35173225",0,35173225,"intergenic_variant",1,0.108,{"v":1e-137,"d":"1.00E-137"},137,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-136,"d":"5.00E-136"},135.301029995663,"(EA)",0.195,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.731,{"v":8E-136,"d":"8.00E-136"},135.096910013008,"(EA)",0.115,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":7e-135,"d":"7.00E-135"},134.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":9e-135,"d":"9.00E-135"},134.04575749056,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":2e-134,"d":"2.00E-134"},133.698970004336,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":5e-134,"d":"5.00E-134"},133.301029995663,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":3e-133,"d":"3.00E-133"},132.52287874528,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":6e-133,"d":"6.00E-133"},132.221848749616,null,8.76,"[7.98-9.54] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":7e-133,"d":"7.00E-133"},132.154901959985,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2E-132,"d":"2.00E-132"},131.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":6e-132,"d":"6.00E-132"},131.221848749616,{"$nulls":3},"NR [2501549] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":6e-131,"d":"6.00E-131"},130.221848749616,null,5.41,"[4.94-5.88] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":9e-131,"d":"9.00E-131"},130.04575749056,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.693,{"v":2e-130,"d":"2.00E-130"},129.698970004336,"(EA)",0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,"NR",{"v":2e-130,"d":"2.00E-130"},129.698970004336,null,0.137,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":3e-130,"d":"3.00E-130"},129.52287874528,null,0.131,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-129,"d":"1.00E-129"},129,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":2e-128,"d":"2.00E-128"},127.698970004336,null,0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116647607,"rs2160669","2014-05-13",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","8,743 East Asian ancestry individuals","11q23.3","A4, C3, A1, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs2160669-?","rs2160669",0,2160669,"3_prime_UTR_variant",0,0.73,{"v":3e-128,"d":"3.00E-128"},127.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[27,"rs7970695",12,121420807,"rs1183910","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-A","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":6e-128,"d":"6.00E-128"},127.221848749616,{"$nulls":3},"NR [2501749] (imputed)","N"]
[18,"rs76722925",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":8e-128,"d":"8.00E-128"},127.096910013008,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121420807,"rs1183910","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-A","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":8e-128,"d":"8.00E-128"},127.096910013008,{"$nulls":3},"NR [2501549] (imputed)","N"]
[5,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":1E-127,"d":"1.00E-127"},127,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":2e-127,"d":"2.00E-127"},126.698970004336,null,0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":3e-126,"d":"3.00E-126"},125.52287874528,"(EA)",0.14,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121420260,"rs7979473","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7979473-?","rs7979473",0,7979473,"intron_variant",0,"NR",{"v":3e-126,"d":"3.00E-126"},125.52287874528,null,0.09719,"[0.089-0.105] unit increase novel","Illumina [6108953] (imputed)","N"]
[5,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":7E-126,"d":"7.00E-126"},125.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":1E-125,"d":"1.00E-125"},125,"(EA)",0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-?","rs261334",0,261334,"intron_variant",0,"NR",{"v":1E-125,"d":"1.00E-125"},125,"(Triglycerides in very large HDL, conditioned)",0.2686627,"[0.25-0.29] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,"NR",{"v":2E-125,"d":"2.00E-125"},124.698970004336,null,0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.725,{"v":2E-125,"d":"2.00E-125"},124.698970004336,"(Asian initial, BMI unadjusted)",0.279,"[0.26-0.3] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[27,"rs7970695",12,121420807,"rs1183910","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-G","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":2e-124,"d":"2.00E-124"},123.698970004336,null,0.149,"[0.14-0.16] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":1e-123,"d":"1.00E-123"},123,"(EA)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,"NR",{"v":9e-123,"d":"9.00E-123"},122.04575749056,null,0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,"NR",{"v":7e-122,"d":"7.00E-122"},121.154901959985,null,0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-122,"d":"8.00E-122"},121.096910013008,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-121,"d":"1.00E-121"},121,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":2E-121,"d":"2.00E-121"},120.698970004336,null,0.126,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-A","rs2954022",0,2954022,"intron_variant",0,0.47,{"v":7e-121,"d":"7.00E-121"},120.154901959985,"(Trans-ethnic initial)",0.078,"[0.072-0.084] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":8e-121,"d":"8.00E-121"},120.096910013008,null,0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-120,"d":"1.00E-120"},120,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":2E-120,"d":"2.00E-120"},119.698970004336,null,0.137,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":3e-120,"d":"3.00E-120"},119.52287874528,null,0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":6e-120,"d":"6.00E-120"},119.221848749616,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[5,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":3e-119,"d":"3.00E-119"},118.52287874528,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-118,"d":"1.00E-118"},118,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44081064,"rs8070723","2011-07-14",21685912,"Hoglinger GU","2011-06-19","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21685912","Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.","Progressive supranuclear palsy","1,069 European ancestry cases, 2,958 European ancestry controls, 45 cases, 329 controls","1,051 European ancestry cases, 3,560 European ancestry controls","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs8070723-?","rs8070723",0,8070723,"intron_variant",0,0.23,{"v":2E-118,"d":"2.00E-118"},117.698970004336,null,5.11,"[4.43-5.91]","Illumina [531451]","N"]
[30,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":3e-118,"d":"3.00E-118"},117.52287874528,null,0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":2e-117,"d":"2.00E-117"},116.698970004336,null,0.08,"[0.08-0.09] unit increase","Illumina [4642479] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":4e-117,"d":"4.00E-117"},116.397940008672,null,6.99,"[6.4-7.58] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":8e-117,"d":"8.00E-117"},116.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":8e-117,"d":"8.00E-117"},116.096910013008,null,0.089,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-116,"d":"3.00E-116"},115.52287874528,{"$nulls":3},"Affymetrix [NR]","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":7e-116,"d":"7.00E-116"},115.154901959985,null,0.101,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":2e-115,"d":"2.00E-115"},114.698970004336,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.12,{"v":2e-115,"d":"2.00E-115"},114.698970004336,null,13.64,"[12.37-14.91] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","up to 4,420 African ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,0.13,{"v":3e-115,"d":"3.00E-115"},114.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[5,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":5e-115,"d":"5.00E-115"},114.301029995663,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":2e-114,"d":"2.00E-114"},113.698970004336,"(Complement C1q tumor necrosis factor-related protein 1, C1QTNF1.6304.8.3)",0.64,"[0.58-0.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-114,"d":"2.00E-114"},113.698970004336,null,0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":6e-114,"d":"6.00E-114"},113.221848749616,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":2E-113,"d":"2.00E-113"},112.698970004336,null,0.217,"[0.2-0.24] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2E-113,"d":"2.00E-113"},112.698970004336,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":1e-112,"d":"1.00E-112"},112,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3e-112,"d":"3.00E-112"},111.52287874528,null,0.119,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63107526,"rs995000","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.3454,{"v":6e-112,"d":"6.00E-112"},111.221848749616,null,0.0618,"[0.056-0.067] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.7,{"v":2e-111,"d":"2.00E-111"},110.698970004336,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":3e-111,"d":"3.00E-111"},110.52287874528,null,0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":5e-111,"d":"5.00E-111"},110.301029995663,null,6.83,"[6.2-7.46] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[16,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.7,{"v":1e-110,"d":"1.00E-110"},110,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.117,{"v":2e-110,"d":"2.00E-110"},109.698970004336,"(Trans-ethnic initial)",0.115,"[0.1-0.13] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[5,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":7e-110,"d":"7.00E-110"},109.154901959985,null,0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":3e-109,"d":"3.00E-109"},108.52287874528,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-?","rs261291",0,261291,"intron_variant",0,"NR",{"v":7e-109,"d":"7.00E-109"},108.154901959985,null,0.1158,"[0.11-0.13] unit increase novel","Illumina [6108953] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,null,0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[19,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":1E-107,"d":"1.00E-107"},107,null,0.076,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.5747,{"v":4e-106,"d":"4.00E-106"},105.397940008672,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.879,{"v":5e-106,"d":"5.00E-106"},105.301029995663,"(EA)",0.127,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs12791103",11,116665079,"rs9804646","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-?","rs9804646",0,9804646,"intergenic_variant",1,"NR",{"v":5e-106,"d":"5.00E-106"},105.301029995663,null,0.1509,"[0.14-0.16] unit decrease novel","Illumina [6108953] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","RP11-115J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1054,{"v":1e-105,"d":"1.00E-105"},105,null,0.0954,"[0.087-0.104] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs139857231",11,116999225,"rs9326248","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","11q23.3","RP11-109L13.1, TAGLN, PCSK7, PAFAH1B2, SIDT2, RP11-109L13.5, AP000892.6","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,9328,7019,"rs9326248-T","rs9326248",0,9326248,"intergenic_variant",1,0.2386935,{"v":2e-105,"d":"2.00E-105"},104.698970004336,"(Proprotein convertase subtilisin/kexin type 7)",0.9929,"[0.91-1.07] unit decrease","Affymetrix [509946]","N"]
[13,"rs56393506",6,161089307,"rs56393506","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,null,{"v":3e-105,"d":"3.00E-105"},104.52287874528,null,7.07,"[6.37-7.77] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,"NR",{"v":5e-105,"d":"5.00E-105"},104.301029995663,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,"NR",{"v":6e-105,"d":"6.00E-105"},104.221848749616,null,0.106,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":8e-105,"d":"8.00E-105"},104.096910013008,"(EA)",0.102,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":9e-105,"d":"9.00E-105"},104.04575749056,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":7e-104,"d":"7.00E-104"},103.154901959985,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.897,{"v":9e-104,"d":"9.00E-104"},103.04575749056,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,0.44,{"v":9e-104,"d":"9.00E-104"},103.04575749056,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs199500",17,44800046,"rs7224296","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Balding type 1","approximately 208,000 European ancestry individuals","NA","17q21.31",null,"NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs7224296-?","rs7224296",0,7224296,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.731,{"v":2e-103,"d":"2.00E-103"},102.698970004336,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.897,{"v":2e-103,"d":"2.00E-103"},102.698970004336,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,"NR",{"v":2e-102,"d":"2.00E-102"},101.698970004336,null,0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":6e-101,"d":"6.00E-101"},100.221848749616,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":8e-101,"d":"8.00E-101"},100.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[30,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":8e-101,"d":"8.00E-101"},100.096910013008,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":2E-100,"d":"2.00E-100"},99.698970004336,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":6e-100,"d":"6.00E-100"},99.2218487496163,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":7e-100,"d":"7.00E-100"},99.1549019599857,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.88,{"v":1E-99,"d":"1.00E-99"},99,"(EA)",0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":2E-99,"d":"2.00E-99"},98.698970004336,"(EA)",0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":9e-99,"d":"9.00E-99"},98.0457574905606,null,0.115,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":3E-98,"d":"3.00E-98"},97.5228787452803,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44095467,"rs58879558","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs58879558-?","rs58879558",0,58879558,"intron_variant",0,"NR",{"v":3E-98,"d":"3.00E-98"},97.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":4e-98,"d":"4.00E-98"},97.397940008672,"(EA)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.12,{"v":1E-97,"d":"1.00E-97"},97,null,2.25,"[2.01-2.49] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[18,"rs76722925",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.896,{"v":2e-97,"d":"2.00E-97"},96.698970004336,"(EA)",0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":7e-97,"d":"7.00E-97"},96.1549019599857,null,7.09,"[6.42-7.76] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil counts","172,275 European ancestry individuals","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-A","rs2248116",0,2248116,"intron_variant",0,0.5626,{"v":1e-96,"d":"1.00E-96"},96,null,0.07316622,"[0.066-0.08] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.809,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(EA)",0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":2e-96,"d":"2.00E-96"},95.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(PH and SEC7 domain-containing protein 1, PSD.13055.53.3)",0.66,"[0.6-0.72] unit increase","Affymetrix [10572788] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.693,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65066186,"rs10761741","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.4176,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,null,0.07693902,"[0.07-0.084] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.39,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,null,1.45,"[1.29-1.61] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":6e-96,"d":"6.00E-96"},95.2218487496163,null,0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.81,{"v":2E-95,"d":"2.00E-95"},94.698970004336,"(EA)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":3e-95,"d":"3.00E-95"},94.5228787452803,null,0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum eosinophil basophil counts","171,771 European ancestry individuals","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-A","rs2248116",0,2248116,"intron_variant",0,0.5627,{"v":3e-95,"d":"3.00E-95"},94.5228787452803,null,0.07275038,"[0.066-0.08] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":9e-95,"d":"9.00E-95"},94.0457574905606,null,0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-94,"d":"2.00E-94"},93.698970004336,null,0.08881,"[0.08-0.097] unit decrease novel","Illumina [6108953] (imputed)","N"]
[18,"rs34669405",8,19928013,"rs6999158","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103243,8612,"rs6999158-T","rs6999158",0,6999158,"intergenic_variant",1,"NR",{"v":2e-94,"d":"2.00E-94"},93.698970004336,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal fluid AB1-42 levels","3,146 individuals","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.101,"[0.091-0.111] unit decrease","Illumina [7358575] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-94,"d":"6.00E-94"},93.2218487496163,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-C","rs3135506",0,3135506,"missense_variant",0,0.071,{"v":2e-93,"d":"2.00E-93"},92.698970004336,null,0.1053,"[0.095-0.115] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.98,{"v":2E-92,"d":"2.00E-92"},91.698970004336,null,0.528,"[0.48-0.58] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[3,"rs1167998",1,63107526,"rs995000","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.309,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,"(Trans-ethnic initial)",0.0691,"[0.062-0.076] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,null,0.073,"[0.065-0.081] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q26","intergenic","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,0.0131,{"v":5e-92,"d":"5.00E-92"},91.3010299956639,null,0.5467,"[0.49-0.6] unit increase","NR [8041861] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":6e-92,"d":"6.00E-92"},91.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":7e-92,"d":"7.00E-92"},91.1549019599857,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,0.146,"[0.13-0.16] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,3.9972339,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.09,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-91,"d":"4.00E-91"},90.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[26,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,"NR",{"v":5E-91,"d":"5.00E-91"},90.3010299956639,null,0.19,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2E-90,"d":"2.00E-90"},89.698970004336,"(Ubiquitin carboxyl-terminal hydrolase 21, USP21.12681.63.3)",0.49,"[0.45-0.53] unit increase","Affymetrix [10572788] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":4E-90,"d":"4.00E-90"},89.397940008672,null,0.118,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2011-06-23",21627779,"Antunez C","2011-05-31","Genome Med","www.ncbi.nlm.nih.gov/pubmed/21627779","The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.","Alzheimer's disease","319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls","4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls","19q13.32","APOE","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":8e-89,"d":"8.00E-89"},88.096910013008,null,1.69,"[NR]","Affymetrix, Illumina [696707] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.36,{"v":5e-88,"d":"5.00E-88"},87.3010299956639,null,0.123,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.892,{"v":1E-87,"d":"1.00E-87"},87,"(EA)",0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,{"$nulls":3},"NR [2501543] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.274,{"v":4e-87,"d":"4.00E-87"},86.397940008672,"(East Asian)",0.32,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-C","rs261291",0,261291,"intron_variant",0,0.37,{"v":6e-87,"d":"6.00E-87"},86.2218487496163,null,0.122,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[3,"rs1167998",1,63124465,"rs4495740","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs4495740-T","rs4495740",0,4495740,"intron_variant",0,0.6678,{"v":2e-86,"d":"2.00E-86"},85.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[26,"rs1269325",11,116654435,"rs603446","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13","ZPR1",null,null,"ENSG00000109917",null,null,"rs603446-T","rs603446",0,603446,"intron_variant",0,0.23,{"v":2e-86,"d":"2.00E-86"},85.698970004336,null,0.0876,"[0.079-0.096] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(EA)",0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.4,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(BMI-adjusted)",0.077,"[0.069-0.085] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[18,"rs34669405",8,19928160,"rs10106652","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103390,8465,"rs10106652-G","rs10106652",0,10106652,"intergenic_variant",1,"NR",{"v":1e-85,"d":"1.00E-85"},85,null,0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.28,{"v":2E-85,"d":"2.00E-85"},84.698970004336,null,2.516,"[2.27-2.76] unit decrease","Affymetrix, Illumina [2573667] (imputed)","N"]
[4,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":3e-85,"d":"3.00E-85"},84.5228787452803,null,0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,0.945,{"v":9e-85,"d":"9.00E-85"},84.0457574905606,"(EA)",0.193,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.707,{"v":5e-84,"d":"5.00E-84"},83.3010299956639,"(EA)",0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","Triglyceride levels","1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":7e-84,"d":"7.00E-84"},83.1549019599857,"(additive)",32.91,"[29.62-36.20] unit increase","Affymetrix [583469]","N"]
[16,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.874,{"v":8e-84,"d":"8.00E-84"},83.096910013008,"(EA)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.89,{"v":9e-84,"d":"9.00E-84"},83.0457574905606,null,0.186,"[0.17-0.21] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-83,"d":"2.00E-83"},82.698970004336,null,3.8717523,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Triglycerides","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":3e-83,"d":"3.00E-83"},82.5228787452803,"(Hispanic)",0.275,"[0.25-0.3] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[3,"rs1167998",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.295,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,"(Trans-ethnic initial)",0.0758,"[0.069-0.083] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[19,"rs2954021",8,126478450,"rs2001846","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27803,731,"rs2001846-T","rs2001846",0,2001846,"intergenic_variant",1,0.4479,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,null,0.0539,"[0.048-0.059] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[36,"rs157595",19,45425460,"rs157595","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-A","rs157595",0,157595,"intergenic_variant",1,0.39,{"v":5e-82,"d":"5.00E-82"},81.3010299956639,null,0.096,"[0.086-0.106] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":5e-81,"d":"5.00E-81"},80.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":4e-80,"d":"4.00E-80"},79.397940008672,null,0.075,"[NR] unit decrease","NR [NR] (imputed)","N"]
[18,"rs76722925",8,19819328,"rs325","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs325-?","rs325",0,325,"intron_variant",0,"NR",{"v":2E-79,"d":"2.00E-79"},78.698970004336,null,0.1483,"[0.13-0.16] unit increase novel","Illumina [6108953] (imputed)","N"]
[18,"rs34669405",8,19928013,"rs6999158","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103243,8612,"rs6999158-T","rs6999158",0,6999158,"intergenic_variant",1,0.708,{"v":3E-79,"d":"3.00E-79"},78.5228787452803,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-78,"d":"2.00E-78"},77.698970004336,"(women)",0.09,"[NR] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":3e-78,"d":"3.00E-78"},77.5228787452803,"(EA)",0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q21.3","ALDH1A2","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.3451,{"v":4E-78,"d":"4.00E-78"},77.397940008672,null,0.0522,"[0.047-0.058] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-77,"d":"1.00E-77"},77,"(mannose)",0.044,"[0.04-0.048] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of white cells","172,378 European ancestry individuals","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-A","rs2248116",0,2248116,"intron_variant",0,0.5626,{"v":1e-77,"d":"1.00E-77"},77,null,0.06536061,"[0.058-0.072] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":1e-77,"d":"1.00E-77"},77,"(Trans-ethnic initial)",0.0622,"[0.055-0.069] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":4e-77,"d":"4.00E-77"},76.397940008672,null,0.137,"[NR] unit decrease","NR [NR] (imputed)","N"]
[4,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":5e-77,"d":"5.00E-77"},76.3010299956639,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":6e-77,"d":"6.00E-77"},76.2218487496163,null,3.2625577,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":9e-77,"d":"9.00E-77"},76.0457574905606,null,3.2591338,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[30,"rs261290",15,58680643,"rs35853021","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs35853021-?","rs35853021",0,35853021,"intron_variant",0,"NR",{"v":7e-76,"d":"7.00E-76"},75.1549019599857,"(XL-HDL-TG)",0.31,"[0.27-0.35] unit increase","Illumina [~ 7700000] (imputed)","N"]
[26,"rs5128",11,116704178,"rs7123454","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","NR","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,390,2289,"rs7123454-?","rs7123454",0,7123454,"intergenic_variant",1,"NR",{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.08217,"[0.073-0.091] unit increase novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5e-75,"d":"5.00E-75"},74.3010299956639,"(Trans-ethnic initial)",0.137,"[0.12-0.15] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.845,{"v":1e-74,"d":"1.00E-74"},74,null,0.0566,"[0.051-0.063] unit decrease","Affymetrix [11535925] (imputed)","N"]
[33,"rs9304381",18,47181668,"rs2156552","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.178,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Trans-ethnic initial)",0.0793,"[0.07-0.088] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.066,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[33,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":3e-73,"d":"3.00E-73"},72.5228787452803,null,0.2326,"[0.21-0.26] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":1e-72,"d":"1.00E-72"},72,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.0692,{"v":3e-72,"d":"3.00E-72"},71.5228787452803,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs190921611",19,45452812,"rs1130742","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC2, APOC4-APOC2",null,null,"ENSG00000234906, ENSG00000224916",null,null,"rs1130742-T","rs1130742",0,1130742,"3_prime_UTR_variant",0,0.261,{"v":5e-72,"d":"5.00E-72"},71.3010299956639,"(PH and SEC7 domain-containing protein 2, PSD2.9118.7.3)",0.49,"[0.43-0.55] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":7E-72,"d":"7.00E-72"},71.1549019599857,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-71,"d":"2.00E-71"},70.698970004336,null,0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.725,{"v":2e-71,"d":"2.00E-71"},70.698970004336,"(Asian initial, BMI unadjusted)",0.182,"[0.16-0.2] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.92,{"v":3e-71,"d":"3.00E-71"},70.5228787452803,"(Trans-ethnic initial)",0.1,"[0.086-0.114] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":4e-71,"d":"4.00E-71"},70.397940008672,null,0.1558,"[0.14-0.17] unit increase novel","Illumina [6108953] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5E-71,"d":"5.00E-71"},70.3010299956639,"(Trans-ethnic initial)",0.121,"[0.11-0.13] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":9e-71,"d":"9.00E-71"},70.0457574905606,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":1E-70,"d":"1.00E-70"},70,null,0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs34669405",8,19928160,"rs10106652","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103390,8465,"rs10106652-G","rs10106652",0,10106652,"intergenic_variant",1,0.725,{"v":1E-70,"d":"1.00E-70"},70,"(EA)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-70,"d":"3.00E-70"},69.5228787452803,null,0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":6e-70,"d":"6.00E-70"},69.2218487496163,"(EA)",0.475,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1e-69,"d":"1.00E-69"},69,null,0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":1e-69,"d":"1.00E-69"},69,null,0.121,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.762,{"v":1e-69,"d":"1.00E-69"},69,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":2e-69,"d":"2.00E-69"},68.698970004336,null,0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC4, APOC4-APOC2, APOC2, CTB-129P6.11","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.3510532,{"v":2e-69,"d":"2.00E-69"},68.698970004336,"(EA, Granulocyte colony-stimulating factor)",0.7496,"[0.67-0.83] unit increase","Affymetrix [509946]","N"]
[13,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.989,{"v":3e-69,"d":"3.00E-69"},68.5228787452803,"(EA)",0.397,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,"NR",{"v":4e-69,"d":"4.00E-69"},68.397940008672,null,0.382,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":6e-69,"d":"6.00E-69"},68.2218487496163,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43994648,"rs17649553","2017-10-24",28892059,"Chang D","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892059","A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.","Parkinson's disease","20,184 European ancestry cases, 397,324 European ancestry controls","5,851 European ancestry cases, 5,866 European ancestry controls","17q21.31","ARHGAP27, CRHR1, KANSL1, SPPL2C, MAPT, STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17649553-C","rs17649553",0,17649553,"intron_variant",0,0.779,{"v":1e-68,"d":"1.00E-68"},68,null,1.2820514,"[1.25-1.32]","Illumina [11933700] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (mother's attained age)","412,937 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-68,"d":"1.00E-68"},68,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":2e-68,"d":"2.00E-68"},67.698970004336,"(EA)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21204025,"rs6544366","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,119492,18160,"rs6544366-T","rs6544366",0,6544366,"intergenic_variant",1,0.2243,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.0549,"[0.049-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs72789541",16,15129459,"rs4985155","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)","8,631 European ancestry individuals","NA","16p13.11","PDXDC1, NTAN1, C16orf45, KIAA0430, MYH11, NDEI, RRN3, PARN","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.648,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.22,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":3e-67,"d":"3.00E-67"},66.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of granulocytes","170,536 European ancestry individuals","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-A","rs2248116",0,2248116,"intron_variant",0,0.5627,{"v":3e-67,"d":"3.00E-67"},66.5228787452803,null,0.06102022,"[0.054-0.068] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.231,{"v":6e-67,"d":"6.00E-67"},66.2218487496163,"(Hispanic)",0.275,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.785,{"v":8e-67,"d":"8.00E-67"},66.096910013008,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.215,{"v":9e-67,"d":"9.00E-67"},66.0457574905606,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":1e-66,"d":"1.00E-66"},66,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":4e-66,"d":"4.00E-66"},65.397940008672,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.86,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(Triglycerides in small VLDL)",0.24,"[0.22-0.26] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.062,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.105,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs55891451",10,96734676,"rs1934963","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","10q23.33","CYP2C9","CYP2C9",null,null,"ENSG00000138109",null,null,"rs1934963-T","rs1934963",0,1934963,"intron_variant",0,0.8,{"v":9e-65,"d":"9.00E-65"},64.0457574905606,"(X-11787)",0.029,"[0.025-0.033] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.3,{"v":1e-64,"d":"1.00E-64"},64,null,0.155,"[0.14-0.17] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,null,0.12,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[26,"rs2266788",11,116639104,"rs10790162","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,"(BMI unadjusted)",0.214,"[0.19-0.24] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-02-09",29263008,"Guerreiro R","2018-01-01","Lancet Neurol","www.ncbi.nlm.nih.gov/pubmed/29263008","Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.","Dementia with Lewy bodies","1,216 European ancestry cases, 3,791 European ancestry controls","527 European ancestry cases, 663 European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.14,{"v":3e-64,"d":"3.00E-64"},63.5228787452803,null,2.46,"[2.22-2.74]","Illumina [8397716] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(VLDL.small, whole)",4.219,"[NR] unit decrease","Illumina [335603]","N"]
[7,"rs11681659",2,136616754,"rs182549","2017-09-05",28588231,"Li M","2017-06-06","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28588231","Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.","1,5-anhydroglucitol levels","7,550 European ancestry individuals","8,790 European ancestry individuals, 2,030 African American individuals","2q21.3","MCM6/LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs182549-C","rs182549",0,182549,"intron_variant",0,0.33,{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(EA)",16.91,"z-score decrease","Affymetrix [at least 8500000] (imputed)","N"]
[7,"rs11681659",2,136616754,"rs182549","2017-09-05",28588231,"Li M","2017-06-06","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28588231","Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.","1,5-anhydroglucitol levels","7,550 European ancestry individuals","8,790 European ancestry individuals, 2,030 African American individuals","2q21.3","MCM6/LCT","MCM6",null,null,"ENSG00000076003",null,null,"rs182549-C","rs182549",0,182549,"intron_variant",0,"NR",{"v":4e-64,"d":"4.00E-64"},63.397940008672,null,16.91,"z-score decrease","Affymetrix [at least 8500000] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.989,{"v":5e-64,"d":"5.00E-64"},63.3010299956639,"(EA)",0.372,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":6e-64,"d":"6.00E-64"},63.2218487496163,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":8e-64,"d":"8.00E-64"},63.096910013008,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,"NR",{"v":8e-64,"d":"8.00E-64"},63.096910013008,null,0.359,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs1374117",11,116708413,"rs670","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","APOA1","APOA1-AS, APOA1",null,null,"ENSG00000235910, ENSG00000118137",null,null,"rs670-T","rs670",0,670,"5_prime_UTR_variant",0,0.167,{"v":8e-64,"d":"8.00E-64"},63.096910013008,"(Beta-endorphin, POMC.2558.51.3)",0.54,"[0.48-0.6] unit decrease","Affymetrix [10572788] (imputed)","N"]
[18,"rs34669405",8,19928013,"rs6999158","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103243,8612,"rs6999158-T","rs6999158",0,6999158,"intergenic_variant",1,"NR",{"v":1e-63,"d":"1.00E-63"},63,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-C","rs515135",0,515135,"intergenic_variant",1,0.83,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.135,"[0.12-0.15] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1012,{"v":2e-63,"d":"2.00E-63"},62.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.11,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.162,"[0.14-0.18] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [2501549] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-63,"d":"3.00E-63"},62.5228787452803,"(Mediator of RNA polymerase II transcription subunit 4, MED4.14021.81.3)",0.42,"[0.38-0.46] unit increase","Affymetrix [10572788] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":4e-63,"d":"4.00E-63"},62.397940008672,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-A","rs676210",0,676210,"missense_variant",0,0.2052,{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.0546,"[0.048-0.061] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45416178,"rs483082","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs483082-?","rs483082",0,483082,"non_coding_transcript_exon_variant",0,0.738441,{"v":1E-62,"d":"1.00E-62"},62,null,2.6436493,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of granulocytes","170,672 European ancestry individuals","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-A","rs2248116",0,2248116,"intron_variant",0,0.5627,{"v":2e-62,"d":"2.00E-62"},61.698970004336,null,0.05873789,"[0.052-0.066] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Dementia and core Alzheimer's disease neuropathologic changes","up to 3,887 cases, up to 1,027 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2883,{"v":2e-62,"d":"2.00E-62"},61.698970004336,"(Primary)",1.6136,"[1.42-1.8] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":4e-62,"d":"4.00E-62"},61.397940008672,null,0.3,"[0.24-0.36] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":3e-61,"d":"3.00E-61"},60.5228787452803,"(Free cholesterol in large LDL, conditioned)",0.5335034,"[0.47-0.60] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":7e-61,"d":"7.00E-61"},60.1549019599857,null,0.099,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":1e-60,"d":"1.00E-60"},60,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19q13.32","APOC2, APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.2,{"v":1e-60,"d":"1.00E-60"},60,null,0.19,"[0.15-0.23] unit increase","Affymetrix [389878]","N"]
[18,"rs76722925",8,19820433,"rs12679834","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8p21.3",null,"LPL",null,null,"ENSG00000175445",null,null,"rs12679834-?","rs12679834",0,12679834,"intron_variant",0,"NR",{"v":9E-60,"d":"9.00E-60"},59.0457574905606,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.234,{"v":9E-60,"d":"9.00E-60"},59.0457574905606,"(East Asian)",0.274,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2346,{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.112,"[0.098-0.126] unit decrease","NR [8041861] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":2e-59,"d":"2.00E-59"},58.698970004336,"(TG)",0.17,"[0.14-0.20] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-59,"d":"4.00E-59"},58.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-G","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.19,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,null,7.91,"[6.93-8.89] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2343,{"v":4e-58,"d":"4.00E-58"},57.397940008672,null,0.0999,"[0.088-0.112] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":5e-58,"d":"5.00E-58"},57.3010299956639,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":6e-58,"d":"6.00E-58"},57.2218487496163,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs34669405",8,19928160,"rs10106652","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103390,8465,"rs10106652-G","rs10106652",0,10106652,"intergenic_variant",1,"NR",{"v":1e-57,"d":"1.00E-57"},57,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","1p13.3","CELSR2, PSRC1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.219,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.124,"[0.11-0.14] unit decrease","Affymetrix [7947838] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":2e-57,"d":"2.00E-57"},56.698970004336,"(EA)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.1052,"[0.092-0.118] unit increase novel","Illumina [6108953] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":6E-57,"d":"6.00E-57"},56.2218487496163,null,4.68,"[4.11-5.25] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1E-56,"d":"1.00E-56"},56,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1E-56,"d":"1.00E-56"},56,"(EA)",0.105,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47158234,"rs9304381","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32682,18486,"rs9304381-T","rs9304381",0,9304381,"intergenic_variant",1,0.8098,{"v":1E-56,"d":"1.00E-56"},56,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131705458,"rs2631367","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","5q31.1",null,"SLC22A5, MIR3936HG",null,null,"ENSG00000197375, ENSG00000233006",null,null,"rs2631367-?","rs2631367",0,2631367,"5_prime_UTR_variant",0,"NR",{"v":2e-56,"d":"2.00E-56"},55.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(Trans-ethnic initial)",0.0564,"[0.049-0.063] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.226,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(East Asian)",0.269,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.789,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(Trans-ethnic initial)",0.0652,"[0.057-0.074] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.393,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(EA)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65154885,"rs10761751","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","10q21.3",null,"JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761751-?","rs10761751",0,10761751,"intron_variant",0,"NR",{"v":4e-56,"d":"4.00E-56"},55.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":5E-56,"d":"5.00E-56"},55.3010299956639,"(EA)",0.413,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-02-05",25898920,"Korostishevsky M","2015-04-22","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/25898920","Genomics and metabolomics of muscular mass in a community-based sample of UK females.","Blood metabolite levels","3,953 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-56,"d":"6.00E-56"},55.2218487496163,"(Mannose levels)",null,null,"Illumina [2300000]","N"]
[5,"rs10184054",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":7e-56,"d":"7.00E-56"},55.1549019599857,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":8e-56,"d":"8.00E-56"},55.096910013008,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":9e-56,"d":"9.00E-56"},55.0457574905606,"(VLDL.total, whole)",6.384,"[NR] unit decrease","Illumina [335603]","N"]
[9,"rs10075801",5,131778452,"rs17622378","2018-04-26",26974007,"Ellinghaus D","2016-03-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26974007","Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.","Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)","8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs17622378-?","rs17622378",0,17622378,"intron_variant",0,"NR",{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(subset analysis)",null,null,"Illumina [130052]","N"]
[26,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0,{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(Trans-ethnic initial)",0.121,"[0.11-0.14] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[36,"rs7246100",19,45436244,"rs7246099","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,1601,9251,"rs7246099-C","rs7246099",0,7246099,"intergenic_variant",1,0.389,{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(Tubulin-specific chaperone A, TBCA.12501.10.3)",0.44,"[0.38-0.5] unit increase","Affymetrix [10572788] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,5.64,"[4.88-6.4] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,0.121,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.237,{"v":9e-55,"d":"9.00E-55"},54.0457574905606,"(East Asian)",0.265,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":2e-54,"d":"2.00E-54"},53.698970004336,null,0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.9351,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.0881,"[0.077-0.099] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.118,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-A","rs1041968",0,1041968,"synonymous_variant",0,0.48,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,null,0.095,"[0.083-0.107] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1E-53,"d":"1.00E-53"},53,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44083402,"rs1991556","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FVC)","approximately 372,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1991556-?","rs1991556",0,1991556,"intron_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,"(females)",3.921738,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-53,"d":"2.00E-53"},52.698970004336,"(APOB.assay, whole)",5.205,"[NR] unit decrease","Illumina [335603]","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":4e-53,"d":"4.00E-53"},52.397940008672,null,0.05965,"[0.052-0.067] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.399,{"v":6e-53,"d":"6.00E-53"},52.2218487496163,"(glucose/mannose + 54 other traits)",0.101,"[NR] unit increase","Affymetrix, Illumina [534665]","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":8e-53,"d":"8.00E-53"},52.096910013008,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":1E-52,"d":"1.00E-52"},52,"(Granulins)",0.7583,"[0.67-0.85] unit decrease","Affymetrix [509946]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3929,{"v":1E-52,"d":"1.00E-52"},52,null,0.034923363,"[0.03-0.039] unit decrease","Affymetrix [11514936] (imputed)","N"]
[9,"rs10075801",5,131770805,"rs2188962","2013-02-12",23128233,"Jostins L","2012-11-01","Nature","www.ncbi.nlm.nih.gov/pubmed/23128233","Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.","Inflammatory bowel disease","12,924 European ancestry cases, 21,442 European ancestry controls","25,683 European ancestry cases, 17,015 European ancestry controls","5q31.1","CSF2, IL13, IL4, IL5, IL3, IRF1, SLC22A5, ACSL6, PDLIM4, SLC22A4","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs2188962-T","rs2188962",0,2188962,"intron_variant",0,0.425,{"v":1E-52,"d":"1.00E-52"},52,null,1.158,"[1.125-1.191]","Affymetrix, Illumina [1230000] (imputed)","N"]
[34,"rs737338",19,11350488,"rs2278426","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","C19orf80","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-T","rs2278426",0,2278426,"missense_variant",0,0.1249,{"v":1E-52,"d":"1.00E-52"},52,null,0.0756,"[0.066-0.085] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":2E-52,"d":"2.00E-52"},51.698970004336,"(EA)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs34669405",8,19928013,"rs6999158","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103243,8612,"rs6999158-T","rs6999158",0,6999158,"intergenic_variant",1,0.708,{"v":3E-52,"d":"3.00E-52"},51.5228787452803,"(EA)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.08,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":6E-52,"d":"6.00E-52"},51.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":1E-51,"d":"1.00E-51"},51,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid AB1-42 levels","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":1E-51,"d":"1.00E-51"},51,null,0.8,"[0.7-0.9] unit decrease","Illumina [8454933] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(EA)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.26,"[0.22-0.30] unit decrease","Affymetrix [389878]","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs200800380",5,131665378,"rs272889","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272889-A","rs272889",0,272889,"intron_variant",0,0.37,{"v":3E-51,"d":"3.00E-51"},50.5228787452803,"(valine/isovalerylcarnitine)",0.039,"[0.033-0.045] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[18,"rs15285",8,19866274,"rs765547","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,41504,70351,"rs765547-?","rs765547",0,765547,"regulatory_region_variant",1,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[22,"rs538711822",10,65101207,"rs10740118","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet distribution width","164,433 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10740118-C","rs10740118",0,10740118,"intron_variant",0,0.419,{"v":3E-51,"d":"3.00E-51"},50.5228787452803,null,0.05482214,"[0.048-0.062] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":5E-51,"d":"5.00E-51"},50.3010299956639,null,0.247,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.06402,"[0.056-0.072] unit increase novel","Illumina [6108953] (imputed)","N"]
[33,"rs77535126",18,47119579,"rs11082764","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs11082764-?","rs11082764",0,11082764,"3_prime_UTR_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.07838,"[0.068-0.089] unit increase novel","Illumina [6108953] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":6E-51,"d":"6.00E-51"},50.2218487496163,"(Trans-ethnic initial)",0.118,"[0.1-0.13] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[3,"rs1167998",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":8e-51,"d":"8.00E-51"},50.096910013008,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":8e-51,"d":"8.00E-51"},50.096910013008,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.215,{"v":9e-51,"d":"9.00E-51"},50.0457574905606,"(EA)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.785,{"v":1E-50,"d":"1.00E-50"},50,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2E-50,"d":"2.00E-50"},49.698970004336,null,0.056,"[NR] unit decrease","NR [NR] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-08-22",29860282,"Scelsi MA","2018-05-30","Brain","www.ncbi.nlm.nih.gov/pubmed/29860282","Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.","Cortical amyloid beta load","936 European ancestry individuals","NA","19q13.32","APOE4","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,null,{"v":3e-50,"d":"3.00E-50"},49.5228787452803,"(uncorrected for APOE4 status)",null,null,"Illumina [5137218] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-50,"d":"3.00E-50"},49.5228787452803,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2018-01-08",29186428,"Tonjes A","2017-11-27","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/29186428","Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin.","Progranulin levels","1,963 European ancestry individuals, 848 Sorbian (founder/genetic isolate) individuals","1800 European ancestry individuals","1p13.3","CELSR2, PSRC1, MYBPHL, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-C","rs660240",0,660240,"3_prime_UTR_variant",0,0.784,{"v":6e-50,"d":"6.00E-50"},49.2218487496163,null,0.169,"unit increase","Affymetrix [2069113] (imputed)","N"]
[33,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,"NR",{"v":7e-50,"d":"7.00E-50"},49.1549019599857,null,0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,{"$nulls":3},"Affymetrix [NR]","N"]
[26,"rs2266788",11,116586283,"rs7350481","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-G","rs7350481",0,7350481,"regulatory_region_variant",1,0.43,{"v":1e-49,"d":"1.00E-49"},49,null,0.241,"[0.21-0.27] unit increase","Illumina [561583]","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":1e-49,"d":"1.00E-49"},49,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","6q25.3","SLC22A3, LPAL2, LPA, PLG","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.065,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,1.31,"[1.27-1.36]","Affymetrix [9149595] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8p23.1","LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,0.124,"[0.1-0.14] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[16,"rs138574868",7,73023881,"rs12531645","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL, AC005089.1",null,null,"ENSG00000009950, ENSG00000274080",null,null,"rs12531645-?","rs12531645",0,12531645,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,0.1056,"[0.092-0.12] unit decrease novel","Illumina [6108953] (imputed)","N"]
[32,"rs16940904",17,43940021,"rs79412431","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","FEV1","321,047 European ancestry individuals","79,005 European ancestry individuals","17q21.31","MAPT-AS1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs79412431-A","rs79412431",0,79412431,"intron_variant",0,0.2161,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,0.0426,"[0.037-0.048] unit decrease","Affymetrix [19819130] (imputed)","N"]
[33,"rs9304381",18,47160953,"rs7241918","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.17,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,1.31,"[1.11-1.51] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.06015,"[0.052-0.068] unit decrease novel","Illumina [6108953] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":1e-48,"d":"1.00E-48"},48,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43994648,"rs17649553","2015-05-09",25064009,"Nalls MA","2014-07-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25064009","Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.","Parkinson's disease","13,708 European ancestry cases, 95,282 European ancestry controls","5,353 European ancestry cases, 5,551 European ancestry controls","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17649553-C","rs17649553",0,17649553,"intron_variant",0,0.774,{"v":2e-48,"d":"2.00E-48"},47.698970004336,null,1.3,"[1.27-1.34]","Illumina [7893274] (imputed)","N"]
[33,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.987,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109821797,"rs4970836","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3425,381,"rs4970836-A","rs4970836",0,4970836,"intergenic_variant",1,0.771,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(Group XIIB secretory phospholipase A2-like protein, PLA2G12B.9380.2.3)",0.42,"[0.36-0.48] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(females)",3.2052002,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":6e-48,"d":"6.00E-48"},47.2218487496163,null,0.106,"[NR] unit increase","NR [NR] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","HDL cholesterol","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":6e-48,"d":"6.00E-48"},47.2218487496163,null,0.07,"[0.060-0.080] mmol/L decrease","Illumina [4642479] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-48,"d":"8.00E-48"},47.096910013008,"(females)",3.1868043,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":1e-47,"d":"1.00E-47"},47,"(EA)",0.092,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.109,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.08,"[0.068-0.092] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.933,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2013-03-06",23247145,"Makela KM","2012-12-17","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23247145","Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.","LDL (oxidized)","2,080 European ancestry individuals","4,238 European ancestry individuals","2p24.1","apoB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.77,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,null,10.5,"U/L increase","Illumina [2543887] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.413,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Trans-ethnic initial)",0.0515,"[0.044-0.059] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neuritic plaque","up to 4,232 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3155,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Ordinal)",0.9467,"[0.82-1.08] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-04-17",29458411,"Chung J","2018-02-20","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/29458411","Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.","Neuritic plaques or neurofibrillary tangles (pleiotropy)","3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-47,"d":"3.00E-47"},46.5228787452803,{"$nulls":3},"NR [6500000] (imputed)","N"]
[5,"rs10184054",2,21206183,"rs6754295","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,121650,16002,"rs6754295-?","rs6754295",0,6754295,"intergenic_variant",1,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,"(VLDL.small, fasting)",4.127,"[NR] unit decrease","Illumina [335603]","N"]
[17,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.086,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet distribution width","164,433 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8668,{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.07616955,"[0.066-0.087] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,null,1.5,"[1.28-1.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neurofibrillary tangles","up to 4,707 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3285,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,"(Ordinal I)",0.6632,"[0.57-0.75] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-47,"d":"6.00E-47"},46.2218487496163,"(females)",3.7354689,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":6e-47,"d":"6.00E-47"},46.2218487496163,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.054,"[NR] unit increase","NR [NR] (imputed)","N"]
[34,"rs142158911",19,11190652,"rs142130958","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,550,9386,"rs142130958-A","rs142130958",0,142130958,"intergenic_variant",1,0.11,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,"(Free cholesterol in large LDL)",0.24,"[0.2-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-T","rs651821",0,651821,"5_prime_UTR_variant",0,0.72,{"v":9E-47,"d":"9.00E-47"},46.0457574905606,"(BMI unadjusted)",0.187,"[0.16-0.21] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[30,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":1E-46,"d":"1.00E-46"},46,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":2E-46,"d":"2.00E-46"},45.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.249,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(East Asian)",0.238,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43940021,"rs79412431","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","Lung function (FVC)","321,047 European ancestry individuals","79,005 European ancestry individuals","17q21.31","MAPT-AS1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs79412431-A","rs79412431",0,79412431,"intron_variant",0,0.2161,{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.0415,"[0.036-0.047] unit decrease","Affymetrix [19819130] (imputed)","N"]
[13,"rs10455872",6,160997118,"rs74617384","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-A","rs74617384",0,74617384,"intron_variant",0,0.942,{"v":4e-46,"d":"4.00E-46"},45.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (both parents in top 10%)","7,182 cases, 79,767 controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.842,{"v":7e-46,"d":"7.00E-46"},45.1549019599857,null,0.0388,"[0.034-0.044] unit increase","Affymetrix [11535925] (imputed)","N"]
[18,"rs34669405",8,19928160,"rs10106652","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103390,8465,"rs10106652-G","rs10106652",0,10106652,"intergenic_variant",1,0.725,{"v":8e-46,"d":"8.00E-46"},45.096910013008,"(EA)",0.059,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.22,{"v":1e-45,"d":"1.00E-45"},45,null,5.99,"[5.11-6.87] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11882123",19,19475088,"rs2965199","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,5524,21547,"rs2965199-?","rs2965199",0,2965199,"intergenic_variant",1,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.762,{"v":6e-45,"d":"6.00E-45"},44.2218487496163,"(EA)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121424861,"rs7310409","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","12q24.31","C12orf27, HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.59,{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,6.8,"[5.70-7.80] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[33,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,"NR",{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":7E-45,"d":"7.00E-45"},44.1549019599857,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",1.5,"[1.28-1.72] unit increase","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":8e-45,"d":"8.00E-45"},44.096910013008,null,0.020889835,"[0.018-0.024] unit increase","NR [~ 10000000] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-A","rs7570971",0,7570971,"intron_variant",0,0.33,{"v":8e-45,"d":"8.00E-45"},44.096910013008,"(1,5-anhydroglucitol (1,5-AG))",0.037,"[0.031-0.043] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-03-15",23263486,"Kottgen A","2012-12-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23263486","Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.","Urate levels","49,825 European ancestry males, 60,522 European ancestry females","Up to 32,813 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-44,"d":"1.00E-44"},44,null,0.074,"[0.063-0.084] mg/dl increase","Affymetrix, Illumina, Perlegen [2450547] (imputed)","N"]
[33,"rs9304381",18,47160953,"rs7241918","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.19,{"v":1e-44,"d":"1.00E-44"},44,null,0.09,"[NR] unit decrease","NR [NR] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-44,"d":"1.00E-44"},44,null,0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.01,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.47,"[0.41-0.53] unit decrease","Affymetrix [389878]","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":2e-44,"d":"2.00E-44"},43.698970004336,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,29206683,"rs3130820","2018-12-17",29483656,"Pardinas AF","2018-02-26","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29483656","Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.","Schizophrenia","40,675 European ancestry cases, 64,643 European ancestry controls","1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls","6p22.1","xMHC","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130820-?","rs3130820",0,3130820,"intron_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,1.281,"[1.25-1.32]","Illumina [8000000] (imputed)","N"]
[18,"rs15285",8,19852045,"rs17489268","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27275,84580,"rs17489268-A","rs17489268",0,17489268,"regulatory_region_variant",1,0.2874,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,3.514711,"[3.02-4.01] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[18,"rs15285",8,19866274,"rs765547","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,41504,70351,"rs765547-?","rs765547",0,765547,"regulatory_region_variant",1,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[22,"rs538711822",10,65050659,"rs7075195","2015-05-05",22139419,"Gieger C","2011-11-30","Nature","www.ncbi.nlm.nih.gov/pubmed/22139419","New gene functions in megakaryopoiesis and platelet formation.","Mean platelet volume","13,106 European ancestry individuals, 1,652 Val Borbera (founder/genetic isolate) individuals, 593 Carlantino (founder/genetic isolate) individuals, 1,146 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,213 South Tyrolean (founder/genetic isolate) individuals, 890 Sorbian (founder/genetic isolate) individuals","Up to 16,960 European ancestry individuals, 855 Cliento (founder/genetic isolate) individuals, 1,023 Talana (founder/genetic isolate) individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7075195-A","rs7075195",0,7075195,"intron_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.014,"[0.012-0.016] ln(fl) increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[26,"rs180327",11,116624703,"rs180326","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs180326-C","rs180326",0,180326,"intron_variant",0,0.22,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.06,"[0.05-0.06] unit increase","Illumina [4642479] (imputed)","N"]
[26,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2009-09-28",17998437,"Li H","2007-11-12","Arch Neurol","www.ncbi.nlm.nih.gov/pubmed/17998437","Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.","Alzheimer's disease","753 European ancestry cases, 736 European ancestry controls","418 European ancestry cases, 249 European ancestry controls","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,{"$nulls":3},"Affymetrix [469438]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.0187927,"[0.016-0.021] unit increase","NR [~ 9732723] (imputed)","N"]
[17,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","11q23.3",null,"ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs5128",11,116703640,"rs5128","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","NR","APOC3",null,null,"ENSG00000110245",null,null,"rs5128-C","rs5128",0,5128,"3_prime_UTR_variant",0,0.916,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(Beta-endorphin, POMC.2558.51.3)",0.6,"[0.52-0.68] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neurofibrillary tangles","up to 4,707 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3219,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(Ordinal II)",0.7871,"[0.68-0.9] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":6e-44,"d":"6.00E-44"},43.2218487496163,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2015-06-08",25350695,"Postmus I","2014-10-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25350695","Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.","Response to statins (LDL cholesterol change)","18,596 European ancestry individuals","23,279 European ancestry individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.087,{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.052,"[0.044-0.060] unit increase","Affymetrix, Illumina, Perlegen [at least 2500000] (imputed)","N"]
[36,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":7e-44,"d":"7.00E-44"},43.1549019599857,"(Valine--tRNA ligase, VARS.13083.18.3)",1.48,"[1.26-1.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs1167998",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-43,"d":"1.00E-43"},43,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.334,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(Trans-ethnic initial)",0.0508,"[0.044-0.058] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.392,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,"(East Asian)",0.201,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","19q13.32","APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,6.61,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":4e-43,"d":"4.00E-43"},42.397940008672,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131672657,"rs56399423","2016-07-24",26192919,"Liu JZ","2015-07-20","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26192919","Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.","Inflammatory bowel disease","12,882 European ancestry cases, 21,770 European ancestry controls","25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls","5q31.1","NR","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs56399423-?","rs56399423",0,56399423,"intron_variant",0,"NR",{"v":4e-43,"d":"4.00E-43"},42.397940008672,"(EA)",null,null,"Affymetrix, Illumina [~ 9000000] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-43,"d":"4.00E-43"},42.397940008672,"(Cofilin-1, CFL1.4203.50.2)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[29,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,"NR",{"v":5e-43,"d":"5.00E-43"},42.3010299956639,null,0.16,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-43,"d":"6.00E-43"},42.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,null,0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-?","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(levels)",0,"[0.80-4.70] % increase","Illumina [NR] (imputed)","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.674,{"v":8e-43,"d":"8.00E-43"},42.096910013008,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19847690,"rs10503669","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-T","rs10503669",0,10503669,"intergenic_variant",1,0.12,{"v":8e-43,"d":"8.00E-43"},42.096910013008,null,0.0426,"[0.037-0.049] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":9e-43,"d":"9.00E-43"},42.0457574905606,null,4.94,"[4.16-5.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[9,"rs10075801",5,131778452,"rs17622378","2016-07-24",26192919,"Liu JZ","2015-07-20","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26192919","Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.","Inflammatory bowel disease","12,882 European ancestry cases, 21,770 European ancestry controls","25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls","5q31.1","NR","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs17622378-G","rs17622378",0,17622378,"intron_variant",0,0.4186,{"v":1E-42,"d":"1.00E-42"},42,"(EA)",1.1465615,"[1.13-1.17]","Affymetrix, Illumina [~ 9000000] (imputed)","N"]
[17,"rs9987289",8,9184231,"rs4240624","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-A","rs4240624",0,4240624,"intron_variant",0,0.925,{"v":1E-42,"d":"1.00E-42"},42,"(Trans-ethnic initial)",0.0818,"[0.07-0.093] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":1E-42,"d":"1.00E-42"},42,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.21,{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.23,"[0.19-0.27] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[18,"rs15285",8,19852045,"rs17489268","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27275,84580,"rs17489268-A","rs17489268",0,17489268,"regulatory_region_variant",1,0.2874,{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,7.776916,"[6.66-8.89] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,"(EA)",1.4285715,null,"Illumina [12023830] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-42,"d":"3.00E-42"},41.5228787452803,null,0.051,"[NR] unit increase","NR [NR] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-42,"d":"3.00E-42"},41.5228787452803,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.399,{"v":4e-42,"d":"4.00E-42"},41.397940008672,"(East Asian)",0.197,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58727325,"rs261332","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-?","rs261332",0,261332,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-42,"d":"4.00E-42"},41.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[5,"rs10184054",2,21237544,"rs673548","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs673548-?","rs673548",0,673548,"intron_variant",0,"NR",{"v":5E-42,"d":"5.00E-42"},41.3010299956639,"(VLDL.total, fasting)",6.624,"[NR] unit decrease","Illumina [335603]","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid AB1-42 levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":6e-42,"d":"6.00E-42"},41.2218487496163,{"$nulls":3},"Illumina [563980]","N"]
[19,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":7e-42,"d":"7.00E-42"},41.1549019599857,null,0.05782,"[0.049-0.066] unit decrease novel","Illumina [6108953] (imputed)","N"]
[10,"rs6882345",5,156392248,"rs12517431","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q33.3","intergenic","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,1982,64176,"rs12517431-T","rs12517431",0,12517431,"intergenic_variant",1,0.6045,{"v":8e-42,"d":"8.00E-42"},41.096910013008,null,0.0365,"[0.031-0.042] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs73001020",19,19394368,"rs138295924","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.11","SUGP1","SUGP1",null,null,"ENSG00000105705",null,null,"rs138295924-A","rs138295924",0,138295924,"intron_variant",0,0.9553,{"v":8e-42,"d":"8.00E-42"},41.096910013008,null,0.098,"[0.084-0.112] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[19,"rs33924196",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7182,{"v":1E-41,"d":"1.00E-41"},41,null,0.041,"[0.035-0.047] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.35,{"v":1E-41,"d":"1.00E-41"},41,"(Hispanic)",0.188,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,"NR",{"v":1E-41,"d":"1.00E-41"},41,null,0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4253,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,6.8761177,"[5.88-7.88] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs10075801",5,131652529,"rs11950562","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs11950562-A","rs11950562",0,11950562,"intron_variant",0,0.52,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(isovalerylcarnitine)",0.036,"[0.03-0.042] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.082,"[NR] unit decrease","NR [NR] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.1065,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,4.9720945,"[4.25-5.7] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.1,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.25,"[0.19-0.31] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":3e-41,"d":"3.00E-41"},40.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":4E-41,"d":"4.00E-41"},40.397940008672,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.9351,{"v":4E-41,"d":"4.00E-41"},40.397940008672,null,0.0762,"[0.065-0.087] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,2.6,"[2.21-2.99] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.36,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.051,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.117,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.136,"[0.12-0.16] unit decrease","Affymetrix [7947838] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1167,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.1359,"[0.12-0.16] unit decrease","NR [8041861] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.933,{"v":6e-41,"d":"6.00E-41"},40.2218487496163,"(EA)",0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":7e-41,"d":"7.00E-41"},40.1549019599857,null,0.101,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":8E-41,"d":"8.00E-41"},40.096910013008,"(Furin, FURIN.6276.16.3)",0.34,"[0.28-0.4] unit increase","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum albumin level","102,223 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.05949,"[0.051-0.068] unit decrease","Illumina [6108953] (imputed)","N"]
[16,"rs62466318",7,72999105,"rs9638182","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.81,{"v":1e-40,"d":"1.00E-40"},40,null,0.1,"[0.084-0.116] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.122,{"v":1e-40,"d":"1.00E-40"},40,"(Hispanic)",0.278,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.059,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2009-02-25",19125160,"Feulner TM","2009-01-07","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/19125160","Examination of the current top candidate genes for AD in a genome-wide association study.","Alzheimer's disease","491 European ancestry cases, 479 European ancestry controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":1e-40,"d":"1.00E-40"},40,{"$nulls":3},"Illumina [~ 550000]","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":2e-40,"d":"2.00E-40"},39.698970004336,null,0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","19q13.32","APOC2, APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":2e-40,"d":"2.00E-40"},39.698970004336,null,0.06,"[0.05-0.07] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72877166,"rs2074755","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2074755-?","rs2074755",0,2074755,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-40,"d":"3.00E-40"},39.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":4e-40,"d":"4.00E-40"},39.397940008672,null,0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-40,"d":"5.00E-40"},39.3010299956639,null,0.072,"[0.06-0.08] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-04-17",29458411,"Chung J","2018-02-20","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/29458411","Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.","Neuritic plaques or cerebral amyloid angiopathy (pleiotropy)","3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":5e-40,"d":"5.00E-40"},39.3010299956639,{"$nulls":3},"NR [6500000] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"NR [2501543] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":1e-39,"d":"1.00E-39"},39,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.355,{"v":1e-39,"d":"1.00E-39"},39,"(Hispanic)",0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":1e-39,"d":"1.00E-39"},39,null,0.1674,"[0.14-0.19] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,null,0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2008-09-08",17474819,"Coon KD","2007-04-01","J Clin Psychiatry","www.ncbi.nlm.nih.gov/pubmed/17474819","A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.","Alzheimer's disease (late onset)","664 European ancestry cases, 422 European ancestry controls","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-39,"d":"1.00E-39"},39,null,4.01,"[NR]","Affymetrix [~ 502627]","N"]
[36,"rs429358",19,45422946,"rs4420638","2008-09-15",17975299,"Webster JA","2007-11-01","Neurodegener Dis","www.ncbi.nlm.nih.gov/pubmed/17975299","Sorl1 as an Alzheimer's disease predisposition gene?","Alzheimer's disease","664 cases, 422 controls","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"Affymetrix [~ 502627]","N"]
[5,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":2e-39,"d":"2.00E-39"},38.698970004336,null,0.151,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.115,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(Hispanic)",0.281,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.586,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(Asian initial, BMI unadjusted)",0.133,"[0.11-0.15] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.274,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,"(East Asian)",0.196,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,"(Endothelial monocyte-activating polypeptide 2, AIMP1.2714.78.2)",0.33,"[0.27-0.39] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.17646,{"v":4e-39,"d":"4.00E-39"},38.397940008672,null,7.44,"[6.32-8.56] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-39,"d":"4.00E-39"},38.397940008672,"(APOB.assay, fasting)",5.251,"[NR] unit decrease","Illumina [335603]","N"]
[26,"rs964184",11,116648917,"rs964184","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","11q23.3","APO-cluster","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":4e-39,"d":"4.00E-39"},38.397940008672,null,0.118,"[0.1-0.14] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","6q25.3","SLC22A3, LPAL2, LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.056243,{"v":5e-39,"d":"5.00E-39"},38.3010299956639,null,1.37,"[1.31- 1.44]","Affymetrix, Illumina [8600000] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2011-09-30",21900290,"Qi Q","2011-09-06","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/21900290","Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes.","Lp (a) levels","1,450 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.07,{"v":5e-39,"d":"5.00E-39"},38.3010299956639,null,1.28,"[1.08-1.48] mg/dL increase","Illumina [~ 2500000] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.1065,{"v":6e-39,"d":"6.00E-39"},38.2218487496163,null,10.830257,"[9.2-12.46] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.053,"[0.045-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs76722925",8,19847690,"rs10503669","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-T","rs10503669",0,10503669,"intergenic_variant",1,0.12,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.0857,"[0.073-0.098] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":1e-38,"d":"1.00E-38"},38,null,0.08,"[0.068-0.092] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":1e-38,"d":"1.00E-38"},38,null,0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Itch intensity from mosquito bite","84,724 European ancestry individuals","NA","5q31.1","C5orf56, IRF1","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-C","rs2248116",0,2248116,"intron_variant",0,0.414,{"v":2e-38,"d":"2.00E-38"},37.698970004336,null,0.0485949,"[0.041-0.056] unit increase","Illumina [13520550] (imputed)","N"]
[21,"rs56068105",10,5256272,"rs17134585","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","10p15.1","AKR1C4","AKR1C4",null,null,"ENSG00000198610",null,null,"rs17134585-T","rs17134585",0,17134585,"intron_variant",0,0.84,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,"(androsterone sulfate/epiandrosterone sulfate)",0.043,"[0.037-0.049] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,null,4.74,"[3.92-5.56] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Dementia and core Alzheimer's disease neuropathologic changes","up to 3,887 cases, up to 1,027 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2864,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,"(Complete)",1.501,"[1.27-1.73] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[10,"rs6882345",5,156394441,"rs9715911","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q33.3","intergenic","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,4175,61983,"rs9715911-A","rs9715911",0,9715911,"intergenic_variant",1,0.6039,{"v":5e-38,"d":"5.00E-38"},37.3010299956639,null,0.035,"[0.03-0.04] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[32,"rs16940904",17,43896032,"rs62057107","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (MTAG)","1,311,438 European ancestry individuals","NA","17q21.31","Intergenic","MAPT-AS1, MAPT-AS1, MAPT-AS1, CRHR1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000278232, ENSG00000263715, ENSG00000282456",null,null,"rs62057107-T","rs62057107",0,62057107,"intron_variant",0,0.2192,{"v":5e-38,"d":"5.00E-38"},37.3010299956639,"(MTAG)",0.0209,"[0.018-0.024] unit decrease","Affymetrix, Illumina [7100000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2010-02-28",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Fasting blood glucose","46,186 European ancestry individuals","76,558 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":6e-38,"d":"6.00E-38"},37.2218487496163,null,0.029,"[0.023-0.035] mmol/L increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.925,{"v":7e-38,"d":"7.00E-38"},37.1549019599857,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131630852,"rs35260072","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Itch intensity from mosquito bite","84,724 European ancestry individuals","NA","5q31.1","SLC22A4","SLC22A4, P4HA2",null,null,"ENSG00000197208, ENSG00000072682",null,null,"rs35260072-C","rs35260072",0,35260072,"intron_variant",0,"NR",{"v":8e-38,"d":"8.00E-38"},37.096910013008,null,0.0482062,"[0.041-0.056] unit increase","Illumina [13520550] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":8e-38,"d":"8.00E-38"},37.096910013008,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-38,"d":"8.00E-38"},37.096910013008,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs35717353",15,58577777,"rs12903590","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12903590-?","rs12903590",0,12903590,"intron_variant",0,"NR",{"v":9e-38,"d":"9.00E-38"},37.0457574905606,null,0.06743,"[0.057-0.078] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,"(TG.assay, whole)",0.07,"[NR] unit increase","Illumina [335603]","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.072,{"v":1e-37,"d":"1.00E-37"},37,"(EA)",0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45416178,"rs483082","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs483082-?","rs483082",0,483082,"non_coding_transcript_exon_variant",0,0.734105,{"v":1e-37,"d":"1.00E-37"},37,"(females)",2.6149259,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[19,"rs2954021",8,126485294,"rs2954027","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954027-A","rs2954027",0,2954027,"intron_variant",0,0.4663,{"v":2e-37,"d":"2.00E-37"},36.698970004336,null,0.04543718,"[0.038-0.052] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.164,{"v":2e-37,"d":"2.00E-37"},36.698970004336,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.151,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.163,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.168,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.927,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs7357361",8,9219887,"rs34597048","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8p23.1",null,"AC022784.1",null,null,"ENSG00000248538",null,null,"rs34597048-?","rs34597048",0,34597048,"intron_variant",0,"NR",{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.0455021,"[0.038-0.053] unit decrease","Affymetrix [20259828] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,0.17,{"v":5e-37,"d":"5.00E-37"},36.3010299956639,"(EA)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs13329672",15,58699937,"rs13329672","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-?","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":7e-37,"d":"7.00E-37"},36.1549019599857,null,0.0965,"[0.082-0.111] unit increase novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.24,{"v":9e-37,"d":"9.00E-37"},36.0457574905606,null,0.096,"[0.08-0.112] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.897,{"v":1e-36,"d":"1.00E-36"},36,"(Asian initial, BMI unadjusted)",0.163,"[0.14-0.19] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[33,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,0.164,{"v":1e-36,"d":"1.00E-36"},36,"(EA)",0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,0.084,"[NR] unit decrease","NR [NR] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,0.97,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(EA)",0.155,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11188153,"rs55791371","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs55791371-A","rs55791371",0,55791371,"intron_variant",0,0.8868,{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,0.1157,"[0.098-0.134] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43919096,"rs2106786","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","17q21.31","SPPL2C","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs2106786-G","rs2106786",0,2106786,"non_coding_transcript_exon_variant",0,0.2242,{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.0537452,"[0.045-0.062] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2014-10-29",24688116,"Deelen J","2014-03-31","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/24688116","Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.","Longevity (90 years and older)","5,406 European ancestry cases, 15,112 European ancestry controls","7,330 European ancestry cases, 61,156 European ancestry controls","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,0.798,{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,1.39,"[1.32-1.47]","Illumina [2470825] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.46,{"v":5E-36,"d":"5.00E-36"},35.3010299956639,null,2.3,"[1.93-2.67] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":5E-36,"d":"5.00E-36"},35.3010299956639,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131770805,"rs2188962","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Crohn's disease","12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls","NA","5q31.1","IL3, CSF2, HINT1, LYRM7, SLC22A4, C5orf56, IRF1, CDC42SE2, RAPGEF6, ACSL6, P4HA2, PDLIM4, SLC22A5, CTC-432M15.3, FNIP1","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs2188962-?","rs2188962",0,2188962,"intron_variant",0,null,{"v":6e-36,"d":"6.00E-36"},35.2218487496163,{"$nulls":3},"Illumina [9560910] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-36,"d":"6.00E-36"},35.2218487496163,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":7e-36,"d":"7.00E-36"},35.1549019599857,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","C-reactive protein levels","75,391 Japanese ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":7e-36,"d":"7.00E-36"},35.1549019599857,null,0.1086,"[0.092-0.126] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2266788",11,116652491,"rs7483863","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs7483863-?","rs7483863",0,7483863,"intron_variant",0,"NR",{"v":8e-36,"d":"8.00E-36"},35.096910013008,null,0.07245,"[0.061-0.084] unit decrease novel","Illumina [6108953] (imputed)","N"]
[33,"rs9304381",18,47158186,"rs10438978","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-C","rs10438978",0,10438978,"intergenic_variant",1,0.81,{"v":8e-36,"d":"8.00E-36"},35.096910013008,null,0.095,"[0.079-0.111] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":1E-35,"d":"1.00E-35"},35,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,0.969,{"v":1E-35,"d":"1.00E-35"},35,"(EA)",0.151,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":1E-35,"d":"1.00E-35"},35,null,0.13,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[35,"rs58542926",19,19329924,"rs2228603","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2228603-T","rs2228603",0,2228603,"missense_variant",0,"NR",{"v":1E-35,"d":"1.00E-35"},35,{"$nulls":3},"NR [2501549] (imputed)","N"]
[3,"rs1167998",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-19",30604766,"Morris AP","2019-01-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30604766","Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.","Estimated glomerular filtration rate","134,070 European ancestry individuals, 143,658 East Asian ancestry individuals, 26,344 Hispanic or Latino ancestry individuals, 8,224 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.534,{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.675,"[0.49-0.86] ml/min/1.73m2 decrease","Affymetrix, Illumina [at least 5248638] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.054,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.121,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(Hispanic)",0.261,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58727325,"rs261332","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-?","rs261332",0,261332,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-35,"d":"2.00E-35"},34.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(TG.by.NMR, whole)",0.052,"[NR] unit increase","Illumina [335603]","N"]
[32,"rs16940904",17,44289232,"rs2732631","2019-01-28",30535121,"Gao XR","2018-12-07","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30535121","Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.","Macular thickness","59,814 European ancestry individuals","8,609 European ancestry individuals","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2732631-?","rs2732631",0,2732631,"intron_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,null,0.959,"[0.8-1.12] unit decrease","Affymetrix [11100000] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":4E-35,"d":"4.00E-35"},34.397940008672,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43654468,"rs62064364","2019-01-28",30535121,"Gao XR","2018-12-07","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30535121","Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.","Macular thickness","59,814 European ancestry individuals","8,609 European ancestry individuals","17q21.31","LRRC37A4P, MAPK8IP1P2","AC091132.4 - DND1P1","ENSG00000267198","ENSG00000282614",null,13872,8769,"rs62064364-?","rs62064364",0,62064364,"intron_variant",1,"NR",{"v":4E-35,"d":"4.00E-35"},34.397940008672,null,0.978,"[0.81-1.14] unit decrease","Affymetrix [11100000] (imputed)","N"]
[6,"rs1728918",2,27635463,"rs1728918","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":5e-35,"d":"5.00E-35"},34.3010299956639,{"$nulls":3},"Affymetrix [NR]","N"]
[17,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.087,{"v":5e-35,"d":"5.00E-35"},34.3010299956639,"(EA)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2013-08-01",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","Hypertriglyceridemia","1,122 Mexican ancestry cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry cases, 1,054 Mexican ancestry controls","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13, KIAA0999","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,0.3,{"v":5e-35,"d":"5.00E-35"},34.3010299956639,null,1.77,"[1.67-1.87]","Illumina [1361436] (imputed)","N"]
[22,"rs538711822",10,65138910,"rs7910927","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7910927-T","rs7910927",0,7910927,"intron_variant",0,0.51,{"v":6e-35,"d":"6.00E-35"},34.2218487496163,"(Men + Women)",0.048,"[0.040-0.056] umol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-04-17",29458411,"Chung J","2018-02-20","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/29458411","Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.","Neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy)","3,135 European ancestry Alzheimer's diseases cases, 463 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":6e-35,"d":"6.00E-35"},34.2218487496163,{"$nulls":3},"NR [6500000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":6e-35,"d":"6.00E-35"},34.2218487496163,"(Selenoprotein S, VIMP.11286.78.3)",0.41,"[0.35-0.47] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":7e-35,"d":"7.00E-35"},34.1549019599857,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":8e-35,"d":"8.00E-35"},34.096910013008,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-35,"d":"8.00E-35"},34.096910013008,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-34,"d":"1.00E-34"},34,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.0752,{"v":1e-34,"d":"1.00E-34"},34,"(Trans-ethnic initial)",0.0842,"[0.072-0.097] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":1e-34,"d":"1.00E-34"},34,"(EA)",0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,0.857,{"v":1e-34,"d":"1.00E-34"},34,"(EA)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049551,"rs11207995","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.67,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,0.076,"[0.064-0.088] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.1,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,0.23,"[0.17-0.29] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.38,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,1.462,"[1.23-1.69] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.674,{"v":3E-34,"d":"3.00E-34"},33.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs11216127",11,116617240,"rs11216126","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,88272,1646,"rs11216126-C","rs11216126",0,11216126,"intergenic_variant",1,0.2,{"v":3E-34,"d":"3.00E-34"},33.5228787452803,null,0.0322,"[0.027-0.037] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":3E-34,"d":"3.00E-34"},33.5228787452803,"(Estrogen sulfotransferase, SULT1E1.9878.3.3)",0.4,"[0.34-0.46] unit decrease","Affymetrix [10572788] (imputed)","N"]
[3,"rs1167998",1,62924448,"rs9988450","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.68,{"v":6E-34,"d":"6.00E-34"},33.2218487496163,null,0.077,"[0.065-0.089] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.814,{"v":6E-34,"d":"6.00E-34"},33.2218487496163,"(Trans-ethnic initial)",0.0669,"[0.054-0.08] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[3,"rs1167998",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":7e-34,"d":"7.00E-34"},33.1549019599857,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity or levels","24,075 European ancestry individuals, 3,420 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.42,{"v":8e-34,"d":"8.00E-34"},33.096910013008,null,0.024,"NR unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.232,{"v":8e-34,"d":"8.00E-34"},33.096910013008,"(Protein MENT, MENT.5744.12.3)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":9e-34,"d":"9.00E-34"},33.0457574905606,"(EA)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2008-09-15",18262040,"Sandhu MS","2008-02-09","Lancet","www.ncbi.nlm.nih.gov/pubmed/18262040","LDL-cholesterol concentrations: a genome-wide association study.","LDL cholesterol","11,685 European ancestry individuals","Up to 4,979 European ancestry individuals","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.19,{"v":1e-33,"d":"1.00E-33"},33,null,0.16,"[0.14-0.18] mmol/L decrease","Affymetrix, Illumina [up to 461986]","N"]
[10,"rs6882345",5,156390297,"rs6882076","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.334,{"v":1e-33,"d":"1.00E-33"},33,"(Trans-ethnic initial)",0.0456,"[0.038-0.053] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[17,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":1e-33,"d":"1.00E-33"},33,"(EA)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,"NR",{"v":1e-33,"d":"1.00E-33"},33,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":2e-33,"d":"2.00E-33"},32.698970004336,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,0.096,{"v":2e-33,"d":"2.00E-33"},32.698970004336,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.067,{"v":2e-33,"d":"2.00E-33"},32.698970004336,"(EA)",0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,"(EA)",0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131652529,"rs11950562","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean platelet volume","164,454 European ancestry individuals","NA","5q31.1","AC034220.3, SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs11950562-C","rs11950562",0,11950562,"intron_variant",0,0.4766,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,null,0.04343237,"[0.036-0.051] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.936,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,"(EA)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs12791103",11,116665079,"rs9804646","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-C","rs9804646",0,9804646,"intergenic_variant",1,"NR",{"v":3e-33,"d":"3.00E-33"},32.5228787452803,null,0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs6602911",13,114544024,"rs7140110","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","13q34",null,"GAS6-AS1, GAS6",null,null,"ENSG00000233695, ENSG00000183087",null,null,"rs7140110-?","rs7140110",0,7140110,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-33,"d":"3.00E-33"},32.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[20,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":4e-33,"d":"4.00E-33"},32.397940008672,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","11q23.3","APOC, APOA","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":4e-33,"d":"4.00E-33"},32.397940008672,"(Hispanic)",0.1567,"[NR] unit increase","Affymetrix [NR]","N"]
[36,"rs429358",19,45411941,"rs429358","2018-08-22",29860282,"Scelsi MA","2018-05-30","Brain","www.ncbi.nlm.nih.gov/pubmed/29860282","Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.","Alzheimer's disease progression score","944 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,null,{"v":4e-33,"d":"4.00E-33"},32.397940008672,"(uncorrected for APOE4 status and baseline cortical amyloid)",null,null,"Illumina [5137218] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":5e-33,"d":"5.00E-33"},32.3010299956639,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal P-tau181p levels","3,146 individuals","NA","19q13.32","APOE, TOMM40, PVRL2, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":5e-33,"d":"5.00E-33"},32.3010299956639,null,0.079,"[0.067-0.091] unit increase","Illumina [7358575] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.77,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,null,5.48,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","Triglycerides","1,678 Mexican ancestry high triglyceride cases, 1,645 Mexican ancestry low triglyceride controls","2,129 Mexican ancestry high triglyceride cases, 2,985 Mexican ancestry low triglyceride controls, 903 Mexican ancestry individuals from 73 dyslipidemic families","11q23.3","ZNF259, BUD13","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":6e-33,"d":"6.00E-33"},32.2218487496163,null,1.89,"[1.69-2.08]","Illumina [1661241] (imputed)","N"]
[26,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,"(EA)",0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43871982,"rs56319902","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","17q21.31",null,"CRHR1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456",null,null,"rs56319902-T","rs56319902",0,56319902,"intron_variant",0,0.2155,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,null,0.0206,"[0.017-0.024] unit decrease","Affymetrix, Illumina [10000000] (imputed)","N"]
[39,"rs200991074",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,"NR",{"v":7e-33,"d":"7.00E-33"},32.1549019599857,null,0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs10455872",6,161123451,"rs4252185","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","6q26","PLG","PLG",null,null,"ENSG00000122194",null,null,"rs4252185-C","rs4252185",0,4252185,"intron_variant",0,0.059661,{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,1.34,"[1.28- 1.41]","Affymetrix, Illumina [8600000] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.21,{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,0.14,"[0.12-0.16] unit increase","Affymetrix [389878]","N"]
[33,"rs9304381",18,47167214,"rs4939883","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.181,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(Trans-ethnic initial)",0.0555,"[0.046-0.065] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","19p13.11","SF4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":2e-32,"d":"2.00E-32"},31.698970004336,{"$nulls":3},"NR [25015711] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(EA)",0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(EA)",0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,null,0.049,"[NR] unit decrease","NR [NR] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,"(EA)",0.056,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.934,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,"(EA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,62965621,"rs35529421","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs35529421-?","rs35529421",0,35529421,"intron_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,null,0.07475,"[0.062-0.087] unit decrease novel","Illumina [6108953] (imputed)","N"]
[5,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,null,0.133,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,"(TG.assay, fasting)",0.075,"[NR] unit increase","Illumina [335603]","N"]
[32,"rs16940904",17,43705601,"rs365825","2017-05-11",27182965,"Pickrell JK","2016-05-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27182965","Detection and interpretation of shared genetic influences on 42 human traits.","Parkinson's disease","9,619 European ancestry cases, 324,522 European ancestry controls","NA","17q21.31","CRHR1, LRRC37A3","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs365825-?","rs365825",0,365825,"intron_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,null,1.2722646,"[1.22-1.33]","Illumina [12438219] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.072,{"v":5e-32,"d":"5.00E-32"},31.3010299956639,"(EA)",0.105,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15132108,"rs2740","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","16p13.11","PDXDC1","PDXDC1, NTAN1",null,null,"ENSG00000179889, ENSG00000157045",null,null,"rs2740-A","rs2740",0,2740,"3_prime_UTR_variant",0,0.71,{"v":5e-32,"d":"5.00E-32"},31.3010299956639,"(linoleate (18:2n6)/dihomo-linolenate (20:3n3 or n6))",0.022,"[0.018-0.026] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.39,{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,8.59,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[32,"rs16940904",17,44096553,"rs62062288","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.211505,{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,11.77,"z score increase","NR [10847151] (imputed)","N"]
[39,"rs200991074",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,"NR",{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.3,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,null,0.0473,"[0.039-0.055] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,"(EA)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43776741,"rs76761706","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs76761706-T","rs76761706",0,76761706,"intron_variant",0,0.215553,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,null,11.76,"z score decrease","NR [10847151] (imputed)","N"]
[18,"rs7819706",8,19848080,"rs17410962","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,23310,88545,"rs17410962-A","rs17410962",0,17410962,"intergenic_variant",1,0.1366,{"v":8e-32,"d":"8.00E-32"},31.096910013008,null,3.9662154,"[3.3-4.63] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[34,"rs737338",19,11350488,"rs2278426","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","19p13.2","NR","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,"NR",{"v":8e-32,"d":"8.00E-32"},31.096910013008,null,0.05178,"[0.043-0.06] unit decrease novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2016-09-08",26252872,"Li QS","2015-08-07","PLoS One","www.ncbi.nlm.nih.gov/pubmed/26252872","Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.","Cerebral amyloid deposition (PET imaging)","up to 883 European and other ancestry individuals","NA","19q13.32","PVRL2, APOE, APOC1, APOC1P1, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.02,{"v":8e-32,"d":"8.00E-32"},31.096910013008,null,0.13,"[NR] unit decrease","Illumina [~ 9000000] (imputed)","N"]
[3,"rs1167998",1,63094207,"rs11485618","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11485618-A","rs11485618",0,11485618,"3_prime_UTR_variant",0,0.691,{"v":1e-31,"d":"1.00E-31"},31,"(Trans-ethnic initial)",0.05,"[0.042-0.058] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[5,"rs10184054",2,21221035,"rs4665710","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-C","rs4665710",0,4665710,"intergenic_variant",1,0.76,{"v":1e-31,"d":"1.00E-31"},31,null,0.082,"[0.068-0.096] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[6,"rs1728918",2,27635463,"rs1728918","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"Affymetrix [NR]","N"]
[17,"rs9987289",8,9185146,"rs2126259","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"NR [2501549] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":1e-31,"d":"1.00E-31"},31,"(EA)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43810896,"rs77804065","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,null,11.693,"z score increase","Affymetrix [10847151] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.931,{"v":2e-31,"d":"2.00E-31"},30.698970004336,"(Asian initial, BMI unadjusted)",0.187,"[0.16-0.22] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.45,{"v":2e-31,"d":"2.00E-31"},30.698970004336,null,0.12,"[0.08-0.16] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2018-05-02",29511194,"Helgadottir A","2018-03-07","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29511194","Genome-wide analysis yields new loci associating with aortic valve stenosis.","Aortic valve stenosis","2,457 Icelandic ancestry cases, 349,342 Icelandic ancestry controls (including non-array genotyped, whole genome imputed individuals)","4,850 European ancestry cases, 451,731 European ancestry controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.062,{"v":2e-31,"d":"2.00E-31"},30.698970004336,null,1.46,"[1.37-1.56]","Illumina [32500000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":2e-31,"d":"2.00E-31"},30.698970004336,"(LDL-C.assay, whole)",6.532,"[NR] unit decrease","Illumina [335603]","N"]
[5,"rs668948",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(APOB.assay, whole)",4.093,"[NR] unit decrease","Illumina [335603]","N"]
[10,"rs6882345",5,156390297,"rs6882076","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.36,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,null,0.046,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.15,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(TG)",0.23,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.067,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(EA)",0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(males)",3.8628085,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":4e-31,"d":"4.00E-31"},30.397940008672,"(EA)",0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-31,"d":"4.00E-31"},30.397940008672,"(Carboxypeptidase A2, CPA2.9276.7.3)",0.3,"[0.24-0.36] unit increase","Affymetrix [10572788] (imputed)","N"]
[29,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,"NR",{"v":9e-31,"d":"9.00E-31"},30.0457574905606,null,0.138,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43555253,"rs56192752","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","17q21.31",null,"PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs56192752-A","rs56192752",0,56192752,"3_prime_UTR_variant",0,0.8218,{"v":9e-31,"d":"9.00E-31"},30.0457574905606,"(conditional-joint)",0.0218,"[0.018-0.026] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[36,"rs79429216",19,45504527,"rs117612135","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","CLPTM1 - RELB","ENSG00000104853","ENSG00000104856",null,7928,161,"rs117612135-?","rs117612135",0,117612135,"regulatory_region_variant",1,"NR",{"v":9e-31,"d":"9.00E-31"},30.0457574905606,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.22,{"v":1e-30,"d":"1.00E-30"},30,null,0.9,"[0.72-1.08] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","Triglyceride levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","11q23.3","BUD13, APOA5, ZNF259, APOA4, APOC3, APOA1, KIAA0999, LOC645044APOA1","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-G","rs651821",0,651821,"5_prime_UTR_variant",0,null,{"v":1e-30,"d":"1.00E-30"},30,"(Japanese)",0.32,"[0.27-0.37] unit increase","Illumina [1294241]","N"]
[27,"rs7970695",12,121420807,"rs1183910","2009-07-12",19567438,"Elliott P","2009-07-01","JAMA","www.ncbi.nlm.nih.gov/pubmed/19567438","Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.","C-reactive protein","17,967 European ancestry and Indian Asian ancestry individuals","13,615 European ancestry and Indian Asian ancestry Individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-T","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":1e-30,"d":"1.00E-30"},30,null,13.8,"[10.9-16.6] % decrease","Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":1e-30,"d":"1.00E-30"},30,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44207932,"rs79301522","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs79301522-A","rs79301522",0,79301522,"intron_variant",0,0.217029,{"v":1e-30,"d":"1.00E-30"},30,null,11.51,"z score decrease","NR [10847151] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.36,{"v":1e-30,"d":"1.00E-30"},30,null,5.5,"[4.64-6.36] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2011-01-14",21087763,"Carrasquillo MM","2010-12-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/21087763","Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.","Progranulin levels","518 European ancestry controls","459 European ancestry controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.21,{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.18,"[0.16-0.20] ng/ml decrease","Illumina [313504]","N"]
[5,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(EA)",0.133,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.024,"[0.02-0.028] unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[18,"rs7819706",8,19845376,"rs7841189","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,20606,91249,"rs7841189-T","rs7841189",0,7841189,"TF_binding_site_variant",1,0.1,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(BMI unadjusted)",0.172,"[0.14-0.2] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.095,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid AB1-42 levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":2e-30,"d":"2.00E-30"},29.698970004336,{"$nulls":3},"Illumina [563980]","N"]
[20,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":3e-30,"d":"3.00E-30"},29.5228787452803,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs143875230",15,43099550,"rs149492745","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.2","NR","TTBK2",null,null,"ENSG00000128881",null,null,"rs149492745-C","rs149492745",0,149492745,"intron_variant",0,"NR",{"v":3e-30,"d":"3.00E-30"},29.5228787452803,null,0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58674308,"rs2043082","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043082-?","rs2043082",0,2043082,"intron_variant",0,"NR",{"v":4e-30,"d":"4.00E-30"},29.397940008672,null,0.04481,"[0.037-0.053] unit increase novel","Illumina [6108953] (imputed)","N"]
[26,"rs6589567",11,116670676,"rs6589567","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","11q23.3","ZPR1, APOA5, APOA4","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,7540,13244,"rs6589567-T","rs6589567",0,6589567,"intergenic_variant",1,0.1178,{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,8.971131,"[7.43-10.52] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs77535126",18,47118923,"rs3786247","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs3786247-?","rs3786247",0,3786247,"3_prime_UTR_variant",0,"NR",{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,0.04427,"[0.037-0.052] unit increase novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2011-11-16",22003152,"Grallert H","2011-10-14","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/22003152","Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.","Lipoprotein-associated phospholipase A2 activity and mass","12,126 European ancestry individuals, 1,538 individuals","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.84,{"v":5e-30,"d":"5.00E-30"},29.3010299956639,"(Activity concentrations)",0.054,"[0.044-0.064] unit decrease","Affymetrix, Illumina [2661766] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":6e-30,"d":"6.00E-30"},29.2218487496163,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,"NR",{"v":6e-30,"d":"6.00E-30"},29.2218487496163,null,0.057,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.52,{"v":7e-30,"d":"7.00E-30"},29.1549019599857,"(Asian initial, BMI unadjusted)",0.1,"[0.082-0.118] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[27,"rs7970695",12,121423956,"rs2393791","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Gamma glutamyl transpeptidase","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs2393791-G","rs2393791",0,2393791,"intron_variant",0,0.48,{"v":7e-30,"d":"7.00E-30"},29.1549019599857,null,7.6E-3,"[0.0062-0.0090] IU/L increase","Affymetrix [~ 2200000] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-30,"d":"7.00E-30"},29.1549019599857,"(males)",3.921353,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":7e-30,"d":"7.00E-30"},29.1549019599857,"(Adhesion G-protein coupled receptor F1, ADGRF1.11243.90.3)",0.38,"[0.32-0.44] unit increase","Affymetrix [10572788] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.416,{"v":8e-30,"d":"8.00E-30"},29.096910013008,null,0.063,"[0.051-0.075] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.21,{"v":8e-30,"d":"8.00E-30"},29.096910013008,"(Indian)",18.69,"[15.46-21.92] unit increase","Illumina [551825]","N"]
[39,"rs200991074",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,"NR",{"v":8e-30,"d":"8.00E-30"},29.096910013008,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.21,{"v":9e-30,"d":"9.00E-30"},29.0457574905606,null,0.18,"[NR] unit increase","Illumina [at least 7000000] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,"NR",{"v":1e-29,"d":"1.00E-29"},29,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,29206683,"rs150817755","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","6p22.1","OR2G1P","AL672167.1",null,null,"ENSG00000197171",null,null,"rs150817755-T","rs150817755",1,3130820,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,"(EA)",1.261,"[1.22-1.3]","Illumina [6627481] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.897,{"v":1e-29,"d":"1.00E-29"},29,"(Hispanic)",0.251,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44096553,"rs62062288","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Risk-taking tendency (4-domain principal component model)","315,894 European ancestry individuals","NA","17q21.31","KANSL1","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.2207,{"v":1e-29,"d":"1.00E-29"},29,null,0.035170935,"[0.029-0.041] unit decrease","Affymetrix [~ 11515000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":2e-29,"d":"2.00E-29"},28.698970004336,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs6882345",5,156398169,"rs1501908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,28306671,"rs13217619","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","6p22.1","NR","ZSCAN31",null,null,"ENSG00000235109",null,null,"rs13217619-T","rs13217619",0,13217619,"intron_variant",0,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,1.25,"[NR]","Illumina [7158791] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","11q23.3",null,"ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,7.83,"[6.22-9.44] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","1p13.3","PSRC1, CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.24,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.16,"[0.14-0.18] unit decrease","Affymetrix [389878]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,"(TG.by.NMR, fasting)",0.056,"[NR] unit increase","Illumina [335603]","N"]
[19,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.46,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,1.84,"[1.51-2.17] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.04,"[NR] unit increase","NR [NR] (imputed)","N"]
[27,"rs7970695",12,121419926,"rs1169284","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","C-reactive protein levels","75,391 Japanese ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1169284-?","rs1169284",0,1169284,"intron_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.05766,"[0.048-0.068] unit decrease novel","Illumina [6108953] (imputed)","N"]
[32,"rs16940904",17,44018399,"rs62061733","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62061733-?","rs62061733",0,62061733,"intron_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,44363929,"rs2696500","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2696500-T","rs2696500",0,2696500,"intron_variant",0,0.214048,{"v":4e-29,"d":"4.00E-29"},28.397940008672,null,11.21,"z score increase","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal T-tau levels","3,146 individuals","NA","19q13.32","APOE, APOC1, TOMM40, PVRL2","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":4e-29,"d":"4.00E-29"},28.397940008672,null,0.078,"[0.064-0.092] unit increase","Illumina [7358575] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.798,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(Hispanic)",0.21,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.2,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,null,0.16,"[0.12-0.20] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":6e-29,"d":"6.00E-29"},28.2218487496163,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43844560,"rs55657917","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","HOXB2","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs55657917-T","rs55657917",0,55657917,"intron_variant",0,0.213403,{"v":7e-29,"d":"7.00E-29"},28.1549019599857,null,11.16,"z score decrease","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":7e-29,"d":"7.00E-29"},28.1549019599857,null,0.1276141,"[NR] unit decrease","Illumina [575353]","N"]
[26,"rs688456",11,116728630,"rs12225230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs12225230-G","rs12225230",0,12225230,"missense_variant",0,0.823,{"v":8e-29,"d":"8.00E-29"},28.096910013008,"(EA)",0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44066172,"rs112385572","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","CRHR1, KANSL1, MAPT, PLEKHM1, SPPL2C, STH","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs112385572-G","rs112385572",0,112385572,"intron_variant",0,"NR",{"v":8e-29,"d":"8.00E-29"},28.096910013008,null,0.0768246,"NR unit decrease","NR [NR] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.11","CILP2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.92,{"v":8e-29,"d":"8.00E-29"},28.096910013008,null,0.122,"[0.1-0.14] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":8e-29,"d":"8.00E-29"},28.096910013008,null,0.072,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","LDL cholesterol","7,565 African American individuals","3,789 African American and Afro-Caribbean individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.25,{"v":9e-29,"d":"9.00E-29"},28.0457574905606,null,0.1815,"[0.15-0.21] unit decrease","Affymetrix [~ 2740000] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.797,{"v":1e-28,"d":"1.00E-28"},28,"(Hispanic)",0.208,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","LDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-C","rs660240",0,660240,"3_prime_UTR_variant",0,0.793,{"v":1e-28,"d":"1.00E-28"},28,"(Hispanic)",0.179,"[0.15-0.21] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","11q23.3","APO-cluster","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.87,{"v":1e-28,"d":"1.00E-28"},28,null,0.102,"[0.084-0.12] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-28,"d":"1.00E-28"},28,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43714850,"rs2942168","2015-04-20",21292315,"Nalls MA","2011-02-01","Lancet","www.ncbi.nlm.nih.gov/pubmed/21292315","Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.","Parkinson's disease","5,333 European ancestry cases, 12,019 European ancestry controls","7,053 cases, 9,007 controls","17q21.31","MAPT","LINC02210-CRHR1, LINC02210-CRHR1, LINC02210",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000204650",null,null,"rs2942168-G","rs2942168",0,2942168,"non_coding_transcript_exon_variant",0,0.78,{"v":1e-28,"d":"1.00E-28"},28,null,1.27,"[1.23-1.31]","Illumina [7689524] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-?","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.1122,"[0.092-0.132] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2e-28,"d":"2.00E-28"},27.698970004336,"(EA)",0.025,"NR unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[11,"rs147662640",6,29244219,"rs144447022","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","6p22.1","NR","AL672167.1",null,null,"ENSG00000197171",null,null,"rs144447022-G","rs144447022",0,144447022,"intron_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,1.25,"[NR]","Illumina [7158791] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.19,"[0.15-0.23] unit decrease","Affymetrix [389878]","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43811072,"rs17563683","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","17q21.31","CRHR1, RP11-105N13.4, RP11-293E1.1","AC217774.2, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000265964, ENSG00000263715, ENSG00000282456",null,null,"rs17563683-G","rs17563683",0,17563683,"intron_variant",0,0.2333,{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.04515636,"[0.037-0.053] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,44018399,"rs62061733","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62061733-A","rs62061733",0,62061733,"intron_variant",0,0.22111,{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,11.07,"z score decrease","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (father's attained age)","415,311 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[39,"rs200991074",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3E-28,"d":"3.00E-28"},27.5228787452803,"(VLDL.large, whole)",0.342,"[NR] unit increase","Illumina [335603]","N"]
[23,"rs4418728",10,94839642,"rs2068888","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","10q23.33","intergenic","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-A","rs2068888",0,2068888,"regulatory_region_variant",1,0.4268,{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,0.0296,"[0.024-0.035] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[32,"rs16940904",17,44192957,"rs17661015","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs17661015-T","rs17661015",0,17661015,"intron_variant",0,0.215131,{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,11.02,"z score decrease","NR [10847151] (imputed)","N"]
[32,"rs16940904",17,44797919,"rs199456","2019-01-28",30535121,"Gao XR","2018-12-07","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30535121","Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.","Macular thickness","59,814 European ancestry individuals","8,609 European ancestry individuals","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199456-?","rs199456",0,199456,"intron_variant",0,"NR",{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,0.86,"[0.7-1.02] unit decrease","Affymetrix [11100000] (imputed)","N"]
[10,"rs6882345",5,156391628,"rs6874202","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,1362,64796,"rs6874202-T","rs6874202",0,6874202,"intergenic_variant",1,0.3857,{"v":4e-28,"d":"4.00E-28"},27.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[32,"rs16940904",17,43896032,"rs62057107","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Highest math class taken (MTAG)","811,539 European ancestry individuals","NA","17q21.31","Intergenic","MAPT-AS1, MAPT-AS1, MAPT-AS1, CRHR1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000278232, ENSG00000263715, ENSG00000282456",null,null,"rs62057107-T","rs62057107",0,62057107,"intron_variant",0,0.2219,{"v":4e-28,"d":"4.00E-28"},27.397940008672,"(MTAG)",0.022,"[0.018-0.026] unit decrease","Affymetrix, Illumina [7100000] (imputed)","N"]
[18,"rs7819706",8,19848080,"rs17410962","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,23310,88545,"rs17410962-A","rs17410962",0,17410962,"intergenic_variant",1,0.1366,{"v":5e-28,"d":"5.00E-28"},27.3010299956639,null,8.334999,"[6.85-9.82] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[29,"rs139974673",15,43820717,"rs55707100","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q15.3","MAP1A","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-T","rs55707100",0,55707100,"missense_variant",0,0.0279,{"v":5e-28,"d":"5.00E-28"},27.3010299956639,null,0.0939,"[0.077-0.111] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.35,{"v":7e-28,"d":"7.00E-28"},27.1549019599857,null,1.98,"[1.59-2.37] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":7e-28,"d":"7.00E-28"},27.1549019599857,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":8e-28,"d":"8.00E-28"},27.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,44324572,"rs555203107","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","17q21.31","NR","MAPK8IP1P1 - AC005829.2","ENSG00000281283","ENSG00000262539",null,2162,12345,"rs555203107-G","rs555203107",1,62073112,"regulatory_region_variant",1,"NR",{"v":8e-28,"d":"8.00E-28"},27.096910013008,null,0.0516895,"[0.042-0.061] unit increase","Affymetrix [16832071] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":1E-27,"d":"1.00E-27"},27,null,0.0422174,"[0.034-0.05] unit increase","Affymetrix [16832071] (imputed)","N"]
[26,"rs90192",11,117091609,"rs236918","2011-01-15",21149283,"Oexle K","2010-12-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21149283","Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.","Iron status biomarkers","Up to 6,616 individuals","NA","11q23.3","PCSK7","PCSK7",null,null,"ENSG00000160613",null,null,"rs236918-C","rs236918",0,236918,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-27,"d":"1.00E-27"},27,"(sTfR)",0.038,"[0.03-0.05] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,43924219,"rs12373124","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","NR","SPPL2C, SPPL2C, SPPL2C, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000277106, ENSG00000185294, ENSG00000278194, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs12373124-C","rs12373124",0,12373124,"synonymous_variant",0,"NR",{"v":1E-27,"d":"1.00E-27"},27,null,0.08,"NR unit decrease","NR [NR] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2017-11-27",29030599,"Joshi PK","2017-10-13","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29030599","Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.","Parental lifespan","up to 586,626 European ancestry individuals, up to 19,433 African ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.142,{"v":1E-27,"d":"1.00E-27"},27,"(EA)",0.9,"years decrease","Affymetrix, Illumina [at least 13643373] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(LDL.total, whole)",0.042,"[NR] unit decrease","Illumina [335603]","N"]
[5,"rs952275",2,21221399,"rs952275","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136866,786,"rs952275-G","rs952275",0,952275,"intergenic_variant",1,0.43,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Free cholesterol in IDL)",0.11,"[0.09-0.13] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,0.056,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58730498,"rs588136","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","15q21.3","LIPC","LIPC-AS1, ALDH1A2, LIPC",null,null,"ENSG00000259293, ENSG00000128918, ENSG00000166035",null,null,"rs588136-T","rs588136",0,588136,"intron_variant",0,0.794,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Trans-ethnic initial)",0.0495,"[0.041-0.058] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[32,"rs16940904",17,44098967,"rs17652520","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Neuroticism","approximately 372,000 European ancestry individuals","NA","17q21.31",null,"MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17652520-?","rs17652520",0,17652520,"intron_variant",0,"NR",{"v":2e-27,"d":"2.00E-27"},26.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,44787312,"rs1378358","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs1378358-T","rs1378358",0,1378358,"intron_variant",0,0.206287,{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,10.86,"z score increase","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neuritic plaque","up to 4,232 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2661,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Case/control)",1.2932,"[1.06-1.53] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Melanoma-associated antigen 3, MAGEA3.12576.21.3)",0.28,"[0.22-0.34] unit increase","Affymetrix [10572788] (imputed)","N"]
[20,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.927,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.925,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(EA)",0.095,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.01336468,"[NR] unit decrease","Illumina [575353]","N"]
[4,"rs629301",1,109817192,"rs7528419","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.782,{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,1.11,"[1.09-1.14]","Affymetrix [9149595] (imputed)","N"]
[9,"rs10075801",5,131770805,"rs2188962","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Inflammatory bowel disease","25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls","NA","5q31.1","IL3, CSF2, HINT1, LYRM7, SLC22A4, C5orf56, IRF1, CDC42SE2, RAPGEF6, ACSL6, P4HA2, PDLIM4, SLC22A5, CTC-432M15.3, FNIP1","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs2188962-?","rs2188962",0,2188962,"intron_variant",0,null,{"v":4e-27,"d":"4.00E-27"},26.397940008672,{"$nulls":3},"Illumina [9725440] (imputed)","N"]
[30,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.861,{"v":4e-27,"d":"4.00E-27"},26.397940008672,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44787313,"rs538628","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","ARL17A, LRRC37A2, NSF, WNT3","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs538628-C","rs538628",0,538628,"intron_variant",0,"NR",{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,0.0800835,"NR unit decrease","NR [NR] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","19q13.32","APOC2, APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.16,{"v":4e-27,"d":"4.00E-27"},26.397940008672,null,0.29,"[0.17-0.41] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2011-12-03",22054870,"De Jager PL","2011-11-03","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/22054870","A genome-wide scan for common variants affecting the rate of age-related cognitive decline.","Cognitive decline","749 European ancestry individuals","1,562 European ancestry individuals, 717 cases","19q13.32","APOE, TOMM40","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":4e-27,"d":"4.00E-27"},26.397940008672,{"$nulls":3},"Affymetrix [672266]","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau:AB1-42 ratio","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":4e-27,"d":"4.00E-27"},26.397940008672,{"$nulls":3},"Illumina [563980]","N"]
[4,"rs629301",1,109818530,"rs646776","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-27,"d":"5.00E-27"},26.3010299956639,null,0.08159,"[0.067-0.096] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs3817588",2,27743154,"rs780092","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-G","rs780092",0,780092,"intron_variant",0,0.33,{"v":5e-27,"d":"5.00E-27"},26.3010299956639,null,0.05,"[0.041-0.059] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2009-07-12",19567438,"Elliott P","2009-07-01","JAMA","www.ncbi.nlm.nih.gov/pubmed/19567438","Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.","C-reactive protein","17,967 European ancestry and Indian Asian ancestry individuals","13,615 European ancestry and Indian Asian ancestry Individuals","19q13.32","APOE, APOCII, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":5e-27,"d":"5.00E-27"},26.3010299956639,null,21.8,"[18.1-25.3] % decrease","Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)","N"]
[18,"rs76722925",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.9,{"v":6e-27,"d":"6.00E-27"},26.2218487496163,"(BMI unadjusted)",0.175,"[0.14-0.21] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal AB1-42 levels in mild cognitive impairment","581 European ancestry MCI dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":6e-27,"d":"6.00E-27"},26.2218487496163,null,0.77,"[0.63-0.91] unit decrease","Illumina [8448490] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":7e-27,"d":"7.00E-27"},26.1549019599857,null,1.91,"[1.54-2.28] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[29,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,0.971,{"v":7e-27,"d":"7.00E-27"},26.1549019599857,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.792,{"v":9e-27,"d":"9.00E-27"},26.0457574905606,"(Hispanic)",0.172,"[0.14-0.2] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.05,{"v":9e-27,"d":"9.00E-27"},26.0457574905606,null,1.33,"[1.27-1.4]","Affymetrix, Illumina [8600000] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-A","rs660240",0,660240,"3_prime_UTR_variant",0,0.21,{"v":1E-26,"d":"1.00E-26"},26,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[5,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.368,{"v":1E-26,"d":"1.00E-26"},26,"(Hispanic)",0.15,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs2603187",4,69338311,"rs969114","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4q13.2","TMPRSS11E","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs969114-A","rs969114",0,969114,"intron_variant",0,0.5722,{"v":1E-26,"d":"1.00E-26"},26,null,0.029,"[0.024-0.034] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-T","rs10808546",0,10808546,"intron_variant",0,0.446,{"v":1E-26,"d":"1.00E-26"},26,"(Trans-ethnic initial)",0.0409,"[0.034-0.048] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":1E-26,"d":"1.00E-26"},26,null,2.85,"[2.32-3.38] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[26,"rs56224630",11,116652207,"rs12286037","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","11q23.3","APOC3, APOA4, APOA5, APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs12286037-T","rs12286037",0,12286037,"intron_variant",0,0.06,{"v":1E-26,"d":"1.00E-26"},26,null,25.82,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[28,"rs6602911",13,114551993,"rs6602909","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","13q34",null,"GAS6",null,null,"ENSG00000183087",null,null,"rs6602909-?","rs6602909",0,6602909,"intron_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs139974673",15,44028047,"rs147233090","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","15q15.3","NR","CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs147233090-T","rs147233090",0,147233090,"intron_variant",0,0.0267,{"v":1E-26,"d":"1.00E-26"},26,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[32,"rs16940904",17,44065740,"rs919462","2018-01-12",29146897,"Pirastu N","2017-11-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29146897","GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.","Male-pattern baldness","25,662 British ancestry cases, 17,928 British ancestry controls","13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls","17q21.31","WNT3, MAPT, PLEKHM1","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs919462-C","rs919462",0,919462,"intron_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,null,0.168393,"[0.14-0.2] unit decrease","Affymetrix [27512692] (imputed)","N"]
[32,"rs16940904",17,44318184,"rs2696668","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","17q21.31","NR","KANSL1 - MAPK8IP1P1","ENSG00000278458","ENSG00000281283",null,15429,2788,"rs2696668-A","rs2696668",0,2696668,"intergenic_variant",1,0.215905,{"v":1E-26,"d":"1.00E-26"},26,null,10.68,"z score decrease","NR [10847151] (imputed)","N"]
[39,"rs200991074",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,0.597,{"v":1E-26,"d":"1.00E-26"},26,"(EA)",0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[39,"rs200991074",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,0.597,{"v":1E-26,"d":"1.00E-26"},26,"(EA)",0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.03923603,"[0.032-0.046] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.367,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.9,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(Asian initial, BMI unadjusted)",0.175,"[0.14-0.21] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2266788",11,116607437,"rs1558861","2008-06-16",18193046,"Kooner JS","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193046","Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.","Triglycerides","1,005 European ancestry male individuals, 1,006 Indian Asian ancestry male individuals","6,827 European ancestry individuals, 2,528 Mexican ancestry individuals, 1,181 Indian Asian ancestry female individuals","11q23.3","MGC13125, LOC440069","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,78469,11449,"rs1558861-C","rs1558861",0,1558861,"regulatory_region_variant",1,0.18,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,17,"[13.28-20.72] % increase","Perlegen [up to 216774]","N"]
[26,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.086,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs688456",11,116726048,"rs12099358","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","11q23.3","SIK3, APOA1-AS, AP000936.4, SIK3-IT1, AP000936.2, RNY4P6, AP000936.1","SIK3, APOA1-AS",null,null,"ENSG00000160584, ENSG00000235910",null,null,"rs12099358-A","rs12099358",0,12099358,"non_coding_transcript_exon_variant",0,0.1557789,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(Beta-endorphin)",0.6234,"[0.51-0.73] unit decrease","Affymetrix [509946]","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44812188,"rs199447","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199447-T","rs199447",0,199447,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,10.659,"z score increase","Affymetrix [10847151] (imputed)","N"]
[36,"rs79429216",19,45504527,"rs117612135","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","CLPTM1 - RELB","ENSG00000104853","ENSG00000104856",null,7928,161,"rs117612135-?","rs117612135",0,117612135,"regulatory_region_variant",1,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[10,"rs6882345",5,156398169,"rs1501908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,0.366,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43811072,"rs17563683","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","17q21.31","CRHR1, RP11-105N13.4, RP11-293E1.1","AC217774.2, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000265964, ENSG00000263715, ENSG00000282456",null,null,"rs17563683-G","rs17563683",0,17563683,"intron_variant",0,0.2333,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.04344178,"[0.035-0.051] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,43950976,"rs10491140","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","17q21.31",null,"MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs10491140-?","rs10491140",0,10491140,"intron_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.0257143,"[0.021-0.031] unit increase","Affymetrix [20259828] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":4e-26,"d":"4.00E-26"},25.397940008672,null,0.066,"[0.054-0.078] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":4e-26,"d":"4.00E-26"},25.397940008672,null,0.1421661,"[NR] unit decrease","Illumina [575353]","N"]
[9,"rs10075801",5,131677642,"rs10075801","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","5q31.1","AC034220.3, SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs10075801-G","rs10075801",0,10075801,"intron_variant",0,0.4856,{"v":7e-26,"d":"7.00E-26"},25.1549019599857,null,0.03816809,"[0.031-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":7e-26,"d":"7.00E-26"},25.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,43810896,"rs77804065","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","ARHGAP27, CRHR1, KANSL1, MAPT, PLEKHM1, SPPL2C, STH","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,0.21716,{"v":8e-26,"d":"8.00E-26"},25.096910013008,null,10.503,"z score increase","Illumina [18485882] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.209,{"v":9e-26,"d":"9.00E-26"},25.0457574905606,"(Hispanic)",0.194,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,43933941,"rs139097404","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q15.3","CATSPER2","CATSPER2",null,null,"ENSG00000166762",null,null,"rs139097404-T","rs139097404",0,139097404,"intron_variant",0,0.9746,{"v":9e-26,"d":"9.00E-26"},25.0457574905606,null,0.0988,"[0.08-0.117] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":1E-25,"d":"1.00E-25"},25,"(EA)",0.056,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs200800380",5,131661156,"rs273913","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs273913-T","rs273913",0,273913,"intron_variant",0,0.38,{"v":1E-25,"d":"1.00E-25"},25,"(3-dehydrocarnitine)",0.026,"[0.02-0.032] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[11,"rs147662640",6,28983274,"rs116757206","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","6p22.1","ZNF311","ZNF311 - OR2AD1P","ENSG00000197935","ENSG00000233650",null,10181,11183,"rs116757206-G","rs116757206",1,3131082,"regulatory_region_variant",1,"NR",{"v":1E-25,"d":"1.00E-25"},25,"(EA)",1.239,"[1.2-1.28]","Illumina [6627481] (imputed)","N"]
[26,"rs12718462",11,116791307,"rs78692246","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","11q23.3",null,"SIK3",null,null,"ENSG00000160584",null,null,"rs78692246-?","rs78692246",0,78692246,"intron_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs17240832",15,58694020,"rs16940212","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940212-T","rs16940212",0,16940212,"intron_variant",0,0.3,{"v":1E-25,"d":"1.00E-25"},25,"(BMI unadjusted)",0.102,"[0.082-0.122] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,"(LDL-C.assay, fasting)",6.892,"[NR] unit decrease","Illumina [335603]","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":1E-25,"d":"1.00E-25"},25,"(Beta-soluble NSF attachment protein, NAPB.12655.30.3)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0163,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.2821,"[0.23-0.34] unit decrease","NR [8041861] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43953719,"rs2214258","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs2214258-C","rs2214258",0,2214258,"intron_variant",0,0.21533,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,10.415,"z score increase","Illumina [18485882] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","19p13.11","CILP2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.92,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.116,"[0.094-0.138] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[39,"rs200991074",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,0.592,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(EA)",0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72971231,"rs13233571","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","7q11.23","BCL7B","BCL7B",null,null,"ENSG00000106635",null,null,"rs13233571-C","rs13233571",0,13233571,"intron_variant",0,0.12,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.057,"[0.047-0.067] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.0422,"[0.034-0.05] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44221836,"rs2696589","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2696589-T","rs2696589",0,2696589,"intron_variant",0,0.19528,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,10.371,"z score increase","Illumina [18485882] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.91,{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.044,"[0.036-0.052] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.63,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,null,1.06,"[1.05-1.08]","Affymetrix, Illumina [247470]","N"]
[9,"rs10075801",5,131677642,"rs10075801","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Myeloid white cell count","169,219 European ancestry individuals","NA","5q31.1","AC034220.3, SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs10075801-G","rs10075801",0,10075801,"intron_variant",0,0.4855,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,null,0.0376138,"[0.03-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[36,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,"(Ubiquitin carboxyl-terminal hydrolase 21, USP21.12681.63.3)",1.12,"[0.9-1.34] unit increase","Affymetrix [10572788] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.09,{"v":6e-25,"d":"6.00E-25"},24.2218487496163,null,1.21,"[0.96-1.46] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[32,"rs16940904",17,43964567,"rs62055546","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","17q21.31","MAPT","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs62055546-A","rs62055546",0,62055546,"intron_variant",0,0.7779,{"v":8e-25,"d":"8.00E-25"},24.096910013008,null,0.027622232,"[0.022-0.033] unit increase","Affymetrix [11514936] (imputed)","N"]
[29,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,"NR",{"v":1e-24,"d":"1.00E-24"},24,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,"(mannose)",0.04725,"[NR] unit decrease","Affymetrix [655658]","N"]
[13,"rs10455872",6,161108144,"rs2315065","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","6q26","PLG","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,10589,11176,"rs2315065-A","rs2315065",0,2315065,"intergenic_variant",1,0.06,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,1.3,"[1.24-1.36]","Affymetrix, Illumina [8600000] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-A","rs112875651",0,112875651,"intron_variant",0,0.3925,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.03782324,"[0.031-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,43573419,"rs62065453","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,5304,10688,"rs62065453-T","rs62065453",0,62065453,"intergenic_variant",1,0.21717,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,10.227,"z score increase","Illumina [18485882] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.08948,"[0.072-0.107] unit decrease novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,"(males)",3.3425252,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs143875230",15,43099550,"rs149492745","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.2","NR","TTBK2",null,null,"ENSG00000128881",null,null,"rs149492745-C","rs149492745",0,149492745,"intron_variant",0,0.973,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(VLDL.large, fasting)",0.362,"[NR] unit increase","Illumina [335603]","N"]
[6,"rs1260326",2,27741237,"rs780094","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4008,{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,1E-3,"[-0.00034-0.00234] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[30,"rs1077835",15,58723939,"rs2070895","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-A","rs2070895",0,2070895,"intron_variant",0,0.43,{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,0.0374,"[0.03-0.045] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-?","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":5e-24,"d":"5.00E-24"},23.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(EA)",0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","11q23.3","APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,null,3.28,"[2.61-4.14]","Affymetrix [~ 2100000] (imputed)","N"]
[32,"rs16940904",17,43853922,"rs56303031","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","17q21.31",null,"LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs56303031-?","rs56303031",0,56303031,"intron_variant",0,"NR",{"v":6e-24,"d":"6.00E-24"},23.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":6e-24,"d":"6.00E-24"},23.2218487496163,null,0.01467512,"[NR] unit decrease","Illumina [575353]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-10-17",28937693,"Clarke TK","2017-07-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28937693","Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).","Alcohol consumption in current drinkers","108,309 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-G","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":7e-24,"d":"7.00E-24"},23.1549019599857,null,0.03,"[0.024-0.036] unit decrease","Affymetrix [12489781] (imputed)","N"]
[9,"rs10075801",5,131567924,"rs11955347","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","5q31.1","P4HA2","P4HA2",null,null,"ENSG00000072682",null,null,"rs11955347-A","rs11955347",0,11955347,"intron_variant",0,0.472,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,"(Complement C1q tumor necrosis factor-related protein 5, C1QTNF5.7810.20.3)",0.25,"[0.21-0.29] unit decrease","Affymetrix [10572788] (imputed)","N"]
[34,"rs142158911",19,11210912,"rs2228671","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs2228671-G","rs2228671",0,2228671,"stop_gained",0,0.88,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,0.16,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.797,{"v":1e-23,"d":"1.00E-23"},23,"(Hispanic)",0.187,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":1e-23,"d":"1.00E-23"},23,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs139857231",11,117079433,"rs199605734","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","PCSK7","PCSK7, AP000892.3",null,null,"ENSG00000160613, ENSG00000280143",null,null,"rs199605734-G","rs199605734",1,1784617,"non_coding_transcript_exon_variant",0,0.208,{"v":1e-23,"d":"1.00E-23"},23,"(Proprotein convertase subtilisin/kexin type 7, PCSK7.4459.68.2)",0.31,"[0.25-0.37] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs190921611",19,45490192,"rs11672748","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","CLPTM1","CLPTM1",null,null,"ENSG00000104853",null,null,"rs11672748-G","rs11672748",0,11672748,"non_coding_transcript_exon_variant",0,0.3171,{"v":1e-23,"d":"1.00E-23"},23,null,10.028075,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.78582,{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,1.12,"[1.10- 1.15]","Affymetrix, Illumina [8600000] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.07,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65010672,"rs10995477","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10995477-C","rs10995477",0,10995477,"intron_variant",0,0.4723,{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.03576595,"[0.029-0.043] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.369,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,"(Hispanic)",0.14,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65134778,"rs2893919","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs2893919-A","rs2893919",0,2893919,"intron_variant",0,0.4446,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","19q13.32",null,"AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-?","rs6857",0,6857,"3_prime_UTR_variant",0,"NR",{"v":3E-23,"d":"3.00E-23"},22.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":4e-23,"d":"4.00E-23"},22.397940008672,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-23,"d":"5.00E-23"},22.3010299956639,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.5398,{"v":6e-23,"d":"6.00E-23"},22.2218487496163,null,0.0546,"[0.044-0.065] unit increase","NR [8041861] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.16,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.467,{"v":8e-23,"d":"8.00E-23"},22.096910013008,"(East Asian)",0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.3,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.1,"[0.06-0.14] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":9e-23,"d":"9.00E-23"},22.0457574905606,null,0.17,"[0.13-0.21] unit increase","Affymetrix [389878]","N"]
[17,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1E-22,"d":"1.00E-22"},22,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":1E-22,"d":"1.00E-22"},22,"(EA)",0.048,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1E-22,"d":"1.00E-22"},22,{"$nulls":3},"Affymetrix [NR]","N"]
[4,"rs629301",1,109817838,"rs660240","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.22,{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(LDL)",0.17,"[0.14-0.20] mmol/l decrease","Illumina [NR] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.35,{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,1.67,"[1.3-2.04] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[29,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43564222,"rs144733372","2018-12-03",28196072,"Hagenaars SP","2017-02-14","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28196072","Genetic prediction of male pattern baldness.","Male-pattern baldness","52,874 British ancestry males",null,"17q21.31","ACBD4, ARHGAP27, FMNL1, HEXIM1, HEXIM2, MAP3K14, PLCD3, PLEKHM1, SPATA32","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs144733372-G","rs144733372",1,9899111,"intron_variant",0,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,0.076714,"NR unit decrease","NR [NR] (imputed)","N"]
[10,"rs6882345",5,156399039,"rs58198139","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q33.3","intergenic","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,8773,57385,"rs58198139-T","rs58198139",0,58198139,"intergenic_variant",1,0.5818,{"v":3e-22,"d":"3.00E-22"},21.5228787452803,null,0.0261,"[0.021-0.031] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":3e-22,"d":"3.00E-22"},21.5228787452803,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-22,"d":"4.00E-22"},21.397940008672,null,0.21751,"[0.17-0.26] unit increase","Affymetrix [7794483] (imputed)","N"]
[9,"rs10075801",5,131677642,"rs10075801","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","5q31.1","AC034220.3, SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs10075801-G","rs10075801",0,10075801,"intron_variant",0,0.4855,{"v":4e-22,"d":"4.00E-22"},21.397940008672,null,0.03509937,"[0.028-0.042] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":4e-22,"d":"4.00E-22"},21.397940008672,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Itch intensity from mosquito bite adjusted by bite size","69,057 European ancestry individuals without immune related conditions","NA","5q31.1","C5orf56, IRF1","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-C","rs2248116",0,2248116,"intron_variant",0,0.414,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.0342719,"[0.027-0.041] unit increase","Illumina [13519193] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.2,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.03,"[0.02-0.04] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental age at death)","208,118 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.842077,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.0436,"[0.035-0.052] unit increase","Affymetrix [11535925] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Platelet count","108,208 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-22,"d":"6.00E-22"},21.2218487496163,null,0.04103,"[0.033-0.049] unit decrease novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau:AB1-42 ratio","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":6e-22,"d":"6.00E-22"},21.2218487496163,{"$nulls":3},"Illumina [563980]","N"]
[35,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":7e-22,"d":"7.00E-22"},21.1549019599857,null,3.11,"[2.37-3.85] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.884,{"v":8e-22,"d":"8.00E-22"},21.096910013008,null,1.14,"[1.11-1.17]","Affymetrix [9149595] (imputed)","N"]
[22,"rs538711822",10,65010672,"rs10995477","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10995477-C","rs10995477",0,10995477,"intron_variant",0,0.4723,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,null,0.03441704,"[0.027-0.041] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,65162153,"rs7896783","2014-03-14",23969696,"Sabater-Lleal M","2013-08-22","Circulation","www.ncbi.nlm.nih.gov/pubmed/23969696","Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.","Fibrinogen","91,323 European ancestry individuals","8,423 African American individuals, 1,447 Hispanic individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896783-A","rs7896783",0,7896783,"intron_variant",0,0.48,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,"(EA)",0.01,"[0.008-0.012] unit decrease","Affymetrix, Illumina [2515567] (imputed)","N"]
[5,"rs952275",2,21232195,"rs693","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs693-A","rs693",0,693,"synonymous_variant",0,0.48,{"v":1e-21,"d":"1.00E-21"},21,null,0.12,"[0.10-0.14] unit increase","Affymetrix [389878]","N"]
[16,"rs138574868",7,73042614,"rs7786376","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","7q11.23","MLXIPL, VPS37D","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3741,39541,"rs7786376-?","rs7786376",0,7786376,"intergenic_variant",1,"NR",{"v":1e-21,"d":"1.00E-21"},21,null,0.06432,"[0.051-0.078] unit decrease novel","Illumina [6108953] (imputed)","N"]
[22,"rs538711822",10,64988931,"rs7916868","2017-06-01",28107422,"de Vries PS","2017-01-20","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28107422","Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.","Fibrinogen levels","91,953 European ancestry individuals (imputed to 1000 Genomes)",null,"10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7916868-?","rs7916868",0,7916868,"intron_variant",0,"NR",{"v":1e-21,"d":"1.00E-21"},21,null,0.0097,"unit increase","Affymetrix, Illumina [10883314] (imputed)","N"]
[31,"rs72789541",16,15130594,"rs6498540","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","16p13.11","NTAN1, PDXDC1, PLA2G10","PDXDC1",null,null,"ENSG00000179889",null,null,"rs6498540-A","rs6498540",0,6498540,"3_prime_UTR_variant",0,0.6989,{"v":1e-21,"d":"1.00E-21"},21,"(lysoPhosphatidylcholine acyl C20:3)",0.0556,"[0.044-0.067] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[6,"rs77200710",2,27755825,"rs4665987","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Creatinine levels","142,097 Japanese ancestry individuals","NA","2p23.3","GCKR, C2orf16","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,9274,4428,"rs4665987-?","rs4665987",0,4665987,"intergenic_variant",1,"NR",{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.03616,"[0.029-0.044] unit decrease novel","Illumina [6108953] (imputed)","N"]
[10,"rs6882345",5,156479323,"rs1553318","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-C","rs1553318",0,1553318,"intron_variant",0,0.65,{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.058,"[0.046-0.07] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.3711,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.0261,"[0.021-0.032] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs538711822",10,65191645,"rs7924036","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","10q21.3",null,"JMJD1C",null,null,"ENSG00000171988",null,null,"rs7924036-T","rs7924036",0,7924036,"intron_variant",0,0.5124,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.0133,"[0.011-0.016] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,"(EA)",0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44126765,"rs113434679","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs113434679-C","rs113434679",0,113434679,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.016272,"[0.013-0.02] unit increase","Affymetrix [18485882] (imputed)","N"]
[36,"rs429358",19,45422160,"rs12721051","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs12721051-G","rs12721051",0,12721051,"3_prime_UTR_variant",0,0.24,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.14,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,"NR",{"v":4e-21,"d":"4.00E-21"},20.397940008672,null,0.042,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":4e-21,"d":"4.00E-21"},20.397940008672,null,1.06,"[0.82-1.3] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.209,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,"(Hispanic)",0.173,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs6882345",5,156398169,"rs1501908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,0.042,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,44028047,"rs147233090","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","15q15.3",null,"CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs147233090-?","rs147233090",0,147233090,"intron_variant",0,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2016-09-12",26421299,"Li J","2015-09-03","Biomed Res Int","www.ncbi.nlm.nih.gov/pubmed/26421299","Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort.","Cingulate cortical amyloid beta load","215 European ancestry early mild cognitive impairment cases, 152 European ancestry late mild cognitive impairment cases, 45 European ancestry Alzheimer disease cases, 190  European ancestry controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,{"$nulls":3},"Illumina [582718]","N"]
[36,"rs5112",19,45430280,"rs5112","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1P1","APOC1P1",null,null,"ENSG00000214855",null,null,"rs5112-G","rs5112",0,5112,"non_coding_transcript_exon_variant",0,0.535,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,"(Protein TMEPAI, PMEPA1.6936.7.3)",0.25,"[0.19-0.31] unit increase","Affymetrix [10572788] (imputed)","N"]
[20,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":6e-21,"d":"6.00E-21"},20.2218487496163,"(EA)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65104500,"rs7896518","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Myeloid white cell count","169,219 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-G","rs7896518",0,7896518,"intron_variant",0,0.4276,{"v":6e-21,"d":"6.00E-21"},20.2218487496163,null,0.03459365,"[0.027-0.042] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[5,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":7e-21,"d":"7.00E-21"},20.1549019599857,null,0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,28349698,"rs13213152","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Depressive symptoms","1,067,913 European ancestry individuals","228,033 European ancestry individuals","6p22.1","NR","ZSCAN12",null,null,"ENSG00000158691",null,null,"rs13213152-G","rs13213152",0,13213152,"3_prime_UTR_variant",0,0.101841204764392,{"v":7e-21,"d":"7.00E-21"},20.1549019599857,null,0.018414358,"[0.015-0.022] unit decrease","NR [NR]","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.25,{"v":7e-21,"d":"7.00E-21"},20.1549019599857,null,0.14,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[5,"rs668948",2,21399216,"rs478442","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,33072,22174,"rs478442-?","rs478442",0,478442,"regulatory_region_variant",1,"NR",{"v":8e-21,"d":"8.00E-21"},20.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[39,"rs200991074",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,0.597,{"v":8e-21,"d":"8.00E-21"},20.096910013008,"(EA)",0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.233,{"v":9e-21,"d":"9.00E-21"},20.0457574905606,"(Hispanic)",0.166,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2008-06-22",18439548,"Ridker PM","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439548","Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.","C-reactive protein","6,345 European ancestry female individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":9e-21,"d":"9.00E-21"},20.0457574905606,null,0.26,"[NR] mg/dl decrease","Illumina [336108]","N"]
[6,"rs202049562",2,27835082,"rs78170284","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","2p23.3",null,"ZNF512, AC074091.1",null,null,"ENSG00000243943, ENSG00000259080",null,null,"rs78170284-?","rs78170284",0,78170284,"intron_variant",0,"NR",{"v":1e-20,"d":"1.00E-20"},20,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[11,"rs147662640",6,29461730,"rs1233491","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","MAS1L, LOC729653","RPS17P1 - AL662860.1","ENSG00000213900","ENSG00000229274",null,4277,3556,"rs1233491-C","rs1233491",0,1233491,"intergenic_variant",1,0.23,{"v":1e-20,"d":"1.00E-20"},20,{"$nulls":3},"Illumina [118177]","N"]
[19,"rs2954021",8,126477978,"rs2001945","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-C","rs2001945",0,2001945,"intergenic_variant",1,0.42,{"v":1e-20,"d":"1.00E-20"},20,null,0.0405,"[0.032-0.049] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-20,"d":"1.00E-20"},20,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":1e-20,"d":"1.00E-20"},20,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid t-tau levels","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":1e-20,"d":"1.00E-20"},20,null,0.55,"[0.43-0.67] unit increase","Illumina [8454470] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-A","rs56131196",0,56131196,"intergenic_variant",1,0.25,{"v":1e-20,"d":"1.00E-20"},20,null,0.14,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[5,"rs10184054",2,21221035,"rs4665710","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-C","rs4665710",0,4665710,"intergenic_variant",1,0.794,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(Sodium-coupled monocarboxylate transporter 1, SLC5A8.13691.10.3)",0.28,"[0.22-0.34] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-A","rs515135",0,515135,"intergenic_variant",1,0.19,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.41,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.023,"[0.019-0.027] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[22,"rs538711822",10,65005399,"rs7902343","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7902343-C","rs7902343",0,7902343,"intron_variant",0,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(EA)",0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44847834,"rs199525","2019-04-17",30818988,"Klein M","2019-03-01","Am J Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30818988","Genetic Markers of ADHD-Related Variations in Intracranial Volume.","Intracranial volume","24,024 European ancestry individuals","NA","17q21.31","NR","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199525-T","rs199525",0,199525,"intron_variant",0,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,9.262,"NR z score increase","NR [9186920] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.232,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(TOM1-like protein 1, TOM1L1.13652.2.3)",0.27,"[0.21-0.33] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2013-07-31",23455636,"Fritsche LG","2013-03-03","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23455636","Seven new loci associated with age-related macular degeneration.","Age-related macular degeneration","6,713 European ancestry cases, 48,402 European ancestry contols, 110 Southern Indian ancestry cases, 119 Southern Indian ancestry controls, 827 Japanese ancestry cases, 3,323 Japanese ancestry controls","9,070 European ancestry cases, 7,683 European ancestry contols, 461 East Asian ancestry cases, 547 East Asian ancestry controls","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.83,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,1.3,"[1.24-1.36]","Affymetrix, Illumina [2442884] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,"(EA)",0.053,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131723288,"rs2073643","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","5q31.1","SLC22A5","SLC22A5",null,null,"ENSG00000197375",null,null,"rs2073643-T","rs2073643",0,2073643,"intron_variant",0,"NR",{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,0.0483183,"[0.038-0.059] unit increase","Illumina [13520550] (imputed)","N"]
[32,"rs16940904",17,44773783,"rs199441","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","17q21.31","intergenic","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199441-A","rs199441",0,199441,"intron_variant",0,0.2175,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,9.219,"z score increase","Illumina [18485882] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.199,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(Hispanic)",0.173,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs62466318",7,73026378,"rs17145750","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","7q11.23","MLX1PL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-T","rs17145750",0,17145750,"intron_variant",0,0.15,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(VLDL diameter)",0.13,"[0.11-0.15] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.9,{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.094,"[0.074-0.114] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-T","rs5167",0,5167,"missense_variant",0,"NR",{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[39,"rs200991074",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,0.592,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65172328,"rs10761756","2017-06-01",28107422,"de Vries PS","2017-01-20","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28107422","Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.","Fibrinogen levels","91,953 European ancestry individuals (imputed to HapMap)",null,"10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761756-?","rs10761756",0,10761756,"intron_variant",0,"NR",{"v":5e-20,"d":"5.00E-20"},19.3010299956639,null,0.0093,"unit increase","Affymetrix, Illumina [2749429] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2016-09-08",26252872,"Li QS","2015-08-07","PLoS One","www.ncbi.nlm.nih.gov/pubmed/26252872","Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.","Cerebral amyloid deposition positivity (PET imaging)","up to 350 European and other ancestry positive individuals, up to 296 European and other ancestry negative individuals","NA","19q13.32","APOE, APOC1, APOC1P1, PVRL2, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.85,{"v":5e-20,"d":"5.00E-20"},19.3010299956639,null,4.72,"[4.39-5.05]","Illumina [~ 9000000] (imputed)","N"]
[32,"rs16940904",17,43849415,"rs79730878","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","17q21.31","CRHR1-IT1-CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs79730878-T","rs79730878",0,79730878,"intron_variant",0,0.771203,{"v":6e-20,"d":"6.00E-20"},19.2218487496163,null,0.0202142,"[0.016-0.025] unit increase","NR [13737936] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.15,{"v":6e-20,"d":"6.00E-20"},19.2218487496163,null,0.15,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.237,{"v":7e-20,"d":"7.00E-20"},19.1549019599857,"(East Asian)",0.144,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":8e-20,"d":"8.00E-20"},19.096910013008,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[29,"rs1561458",15,44245931,"rs2929282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs2929282-A","rs2929282",0,2929282,"intron_variant",0,0.946,{"v":8e-20,"d":"8.00E-20"},19.096910013008,"(EA)",0.089,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43731719,"rs241036","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs241036-A","rs241036",0,241036,"non_coding_transcript_exon_variant",0,0.217056,{"v":8e-20,"d":"8.00E-20"},19.096910013008,null,9.11,"z score decrease","NR [10847151] (imputed)","N"]
[32,"rs16940904",17,44013475,"rs79857651","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs79857651-A","rs79857651",0,79857651,"intron_variant",0,0.215594,{"v":9e-20,"d":"9.00E-20"},19.0457574905606,null,9.1,"z score increase","NR [10847151] (imputed)","N"]
[3,"rs1167998",1,62926371,"rs7547965","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs7547965-A","rs7547965",0,7547965,"intron_variant",0,0.658,{"v":1e-19,"d":"1.00E-19"},19,"(ANGPTL3)",0.228,"[0.18-0.28] unit increase","Illumina [> 1000000] (imputed)","N"]
[18,"rs76722925",8,19847690,"rs10503669","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-A","rs10503669",0,10503669,"intergenic_variant",1,0.11,{"v":1e-19,"d":"1.00E-19"},19,"(BMI unadjusted)",0.16,"[0.13-0.19] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":1e-19,"d":"1.00E-19"},19,"(IDL.total, whole)",0.107,"[NR] unit increase","Illumina [335603]","N"]
[4,"rs629301",1,109822166,"rs599839","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Metabolite levels","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.06,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(LDL)",5.2254,"[4.09-6.37] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.93,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(BMI unadjusted)",0.173,"[0.14-0.21] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-?","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs157580-G","rs157580",0,157580,"intron_variant",0,0.33,{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.11,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Hippocampal volume","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.47,"[0.37-0.57] unit decrease","Illumina [8056701] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72975702,"rs111269058","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","7q11.23","BCL7B","BCL7B - TBL2","ENSG00000106635","ENSG00000106638",null,3682,6161,"rs111269058-T","rs111269058",0,111269058,"intergenic_variant",1,0.12,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(BMI-adjusted)",0.054,"[0.042-0.066] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[22,"rs538711822",10,65066186,"rs10761741","2016-12-01",26910538,"Choi SH","2016-02-24","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26910538","Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.","Vascular endothelial growth factor levels","9541 European ancestry individuals, 1,115 Cilento (founder/genetic isolated) individuals, 897 Ogliastran (founder/genetic isolated) individuals, 1,759 Val Borbera (founder/genetic isolated) individuals","2,141 European ancestry individuals, 659 Sorbian (founder/genetic isolated) individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761741-T","rs10761741",0,10761741,"intron_variant",0,0.43,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.08,"[0.062-0.098] unit increase","Affymetrix, Illumina [6705861] (imputed)","N"]
[37,"rs6129624",20,39203782,"rs2865505","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","20q12",null,"AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,448785,110706,"rs2865505-?","rs2865505",0,2865505,"intergenic_variant",1,"NR",{"v":3e-19,"d":"3.00E-19"},18.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum albumin level","Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals","NA","2p23.3","GCKR-FNDC4","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":4e-19,"d":"4.00E-19"},18.397940008672,null,0.0138,"[0.011-0.017] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[18,"rs76722925",8,19847690,"rs10503669","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-A","rs10503669",0,10503669,"intergenic_variant",1,0.1,{"v":4e-19,"d":"4.00E-19"},18.397940008672,null,2.09,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[32,"rs16940904",17,43659975,"rs2668680","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","17q21.31","NR","AC091132.4 - DND1P1","ENSG00000267198","ENSG00000282614",null,19379,3262,"rs2668680-C","rs2668680",0,2668680,"intron_variant",1,0.177,{"v":4e-19,"d":"4.00E-19"},18.397940008672,null,0.0174888,"[0.014-0.021] unit decrease","NR [~ 9732723] (imputed)","N"]
[29,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,"NR",{"v":5e-19,"d":"5.00E-19"},18.3010299956639,null,0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,"(EA)",0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs4818005",21,40574305,"rs2183573","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","21q22.2","BRWD1","BRWD1",null,null,"ENSG00000185658",null,null,"rs2183573-A","rs2183573",0,2183573,"missense_variant",0,0.4103,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,null,0.0182,"[0.014-0.022] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs668948",2,21274167,"rs13011615","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,7222,72622,"rs13011615-?","rs13011615",0,13011615,"intergenic_variant",1,"NR",{"v":6e-19,"d":"6.00E-19"},18.2218487496163,"(Free cholesterol in large LDL, conditioned)",0.1247424,"[0.097-0.152] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.44,{"v":6e-19,"d":"6.00E-19"},18.2218487496163,null,0.61,"[0.47-0.75] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[10,"rs6882345",5,156479323,"rs1553318","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-G","rs1553318",0,1553318,"intron_variant",0,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs10047462",11,116908283,"rs7115242","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","11q23.3","SIK3","SIK3",null,null,"ENSG00000160584",null,null,"rs7115242-T","rs7115242",0,7115242,"intron_variant",0,0.1027,{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,7.777633,"[6.06-9.5] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs77535126",18,47118923,"rs3786247","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs3786247-T","rs3786247",0,3786247,"3_prime_UTR_variant",0,0.6,{"v":7e-19,"d":"7.00E-19"},18.1549019599857,"(Asian initial, BMI unadjusted)",0.094,"[0.074-0.114] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.696,{"v":8e-19,"d":"8.00E-19"},18.096910013008,"(Hispanic)",0.13,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.696,{"v":1e-18,"d":"1.00E-18"},18,"(Hispanic)",0.117,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs15285-T","rs15285",0,15285,"3_prime_UTR_variant",0,0.2675,{"v":1e-18,"d":"1.00E-18"},18,null,0.109238155,"[0.085-0.134] mg/dl increase","Illumina [24111857] (imputed)","N"]
[29,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,0.969,{"v":1e-18,"d":"1.00E-18"},18,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44357351,"rs17665188","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs17665188-T","rs17665188",0,17665188,"intron_variant",0,0.213949,{"v":1e-18,"d":"1.00E-18"},18,null,8.79,"z score decrease","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid AB1-42 levels","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":1e-18,"d":"1.00E-18"},18,null,301.1457,"[NR] unit increase","Illumina [575353]","N"]
[38,"rs4818005",21,40588819,"rs4818005","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Smoking initiation (ever regular vs never regular) (MTAG)","up to 1,359,002 European ancestry individuals","NA","21q22.2","NR","TIMM9P2, BRWD1",null,null,"ENSG00000232608, ENSG00000185658",null,null,"rs4818005-A","rs4818005",0,4818005,"intron_variant",0,0.581,{"v":1e-18,"d":"1.00E-18"},18,null,0.00983799,"[0.0077-0.012] unit decrease","NR [9732723] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","2p24.1",null,"APOB",null,null,"ENSG00000084674",null,null,"rs1042034-?","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.03202804,"[0.025-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-C","rs55730499",0,55730499,"intron_variant",0,0.92,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.0361,"[0.028-0.044] unit decrease","Affymetrix [11535925] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(EA)",0.072,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-T","rs12686004",0,12686004,"intron_variant",0,0.21,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.0217,"[0.017-0.027] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44787312,"rs1378358","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Neuroticism","523,783 European ancestry individuals","59,206 European ancestry individuals","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs1378358-T","rs1378358",0,1378358,"intron_variant",0,0.217292507620124,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.019632332,"[0.015-0.024] unit increase","NR [NR]","N"]
[36,"rs429358",19,45410002,"rs769449","2013-09-27",23562540,"Cruchaga C","2013-04-04","Neuron","www.ncbi.nlm.nih.gov/pubmed/23562540","GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.","Alzheimer's disease biomarkers","591 European ancestry cases, 687 European ancestry controls",null,"19q13.32","APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(ptau)",0.091,"[NR] unit increase","Illumina [5815690] (imputed)","N"]
[3,"rs1167998",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(EA)",0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.63,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,1.06,"[1.04-1.07]","Affymetrix, Illumina [247470]","N"]
[18,"rs76722925",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.89,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(BMI unadjusted)",0.165,"[0.13-0.2] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[22,"rs538711822",10,65050659,"rs7075195","2014-03-25",24026423,"Shameer K","2013-09-12","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/24026423","A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.","Mean platelet volume","6,291 European ancestry individuals","NA","10q21.3","JMJD1C, NRBF2, REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7075195-A","rs7075195",0,7075195,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.13,"[NR] unit increase","Illumina [476395]","N"]
[26,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","11q23.3","APOA4, APOA5, APOA1, APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(Trans-ethnic initial)",0.0855,"[0.07-0.101] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(APOB.assay, fasting)",4.492,"[NR] unit decrease","Illumina [335603]","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid p-tau levels","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, OMM40, APOC1, APOC1P1, APOC4, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.51,"[0.39-0.63] unit increase","Illumina [8454806] (imputed)","N"]
[30,"15:58682029_TGAA_T",15,58684282,"rs16940170","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","15q21.3","LOC101928635","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940170-?","rs16940170",0,16940170,"intron_variant",0,"NR",{"v":4e-18,"d":"4.00E-18"},17.397940008672,{"$nulls":3},"Affymetrix [344366]","N"]
[33,"rs77960347",18,47109955,"rs77960347","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","18q21.1",null,"LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-?","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":4e-18,"d":"4.00E-18"},17.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":5e-18,"d":"5.00E-18"},17.3010299956639,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs3817588",2,27743154,"rs780092","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Metabolite levels","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-G","rs780092",0,780092,"intron_variant",0,0.33,{"v":5e-18,"d":"5.00E-18"},17.3010299956639,"(ALB)",0.0232,"[-0.02972-0.07612] g/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[18,"rs15285",8,19865175,"rs2083637","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,40405,71450,"rs2083637-G","rs2083637",0,2083637,"regulatory_region_variant",1,0.26,{"v":6e-18,"d":"6.00E-18"},17.2218487496163,null,0.11,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[32,"rs16940904",17,44773783,"rs199441","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Experiencing mood swings","373,733 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199441-A","rs199441",0,199441,"intron_variant",0,0.217502,{"v":6e-18,"d":"6.00E-18"},17.2218487496163,null,8.63,"z score increase","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2017-06-27",28183528,"Jun GR","2017-02-06","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/28183528","Transethnic genome-wide scan identifies novel Alzheimer's disease loci.","Alzheimer's disease","13,100 European ancestry cases, 13,220 European ancestry controls, 1,472 African American cases, 3,511 African American controls, 951 Japanese ancestry cases, 894 Japanese ancestry controls, 51 Israeli-Arab ancestry cases, 64 Israeli-Arab ancestry controls","5,813 European ancestry cases, 20,474 European ancestry controls","19q13.32","NR","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,"NR",{"v":7e-18,"d":"7.00E-18"},17.1549019599857,"(Japanese)",3.22,"[2.45-4.24]","NR [NR]","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":8e-18,"d":"8.00E-18"},17.096910013008,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19885726,"rs11984636","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8p21.3","MET","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,60956,50899,"rs11984636-T","rs11984636",0,11984636,"intergenic_variant",1,0.89,{"v":8e-18,"d":"8.00E-18"},17.096910013008,"(Asian initial, BMI unadjusted)",0.165,"[0.13-0.2] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2011-11-16",22003152,"Grallert H","2011-10-14","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/22003152","Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.","Lipoprotein-associated phospholipase A2 activity and mass","12,126 European ancestry individuals, 1,538 individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.79,{"v":1e-17,"d":"1.00E-17"},17,"(Activity concentrations)",0.035,"[0.027-0.043] unit increase","Affymetrix, Illumina [2661766] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72877166,"rs2074755","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2074755-?","rs2074755",0,2074755,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-17,"d":"1.00E-17"},17,{"$nulls":3},"Affymetrix [NR]","N"]
[17,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.087,{"v":1e-17,"d":"1.00E-17"},17,"(EA)",0.07,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.705,{"v":1e-17,"d":"1.00E-17"},17,"(Hispanic)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.588,{"v":1e-17,"d":"1.00E-17"},17,"(East Asian)",0.116,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44192618,"rs4606752","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs4606752-G","rs4606752",0,4606752,"intron_variant",0,0.2266,{"v":1e-17,"d":"1.00E-17"},17,null,0.03608263,"[0.028-0.044] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0169,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.36090583,"[0.28-0.44] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.93,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(BMI unadjusted)",0.162,"[0.13-0.2] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-A","rs668948",0,668948,"intergenic_variant",1,0.815,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.063,"[0.048-0.078] unit increase","NR [8041861] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.5895,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.064,"[0.048-0.08] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.596,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(East Asian)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.164,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(EA)",0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.89,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(East Asian)",0.194,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs6602911",13,114551993,"rs6602909","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","13q34","GAS6","GAS6",null,null,"ENSG00000183087",null,null,"rs6602909-C","rs6602909",0,6602909,"intron_variant",0,0.3251,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,0.03194904,"[0.025-0.039] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs72789541",16,15129970,"rs7200543","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","16p13.11","NTAN1, PDXDC1, PLA2G10","PDXDC1",null,null,"ENSG00000179889",null,null,"rs7200543-A","rs7200543",0,7200543,"synonymous_variant",0,0.6987,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(Phosphatidylcholine diacyl C38:3)",0.0413,"[0.032-0.051] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[36,"rs5112",19,45430280,"rs5112","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1P1","APOC1P1",null,null,"ENSG00000214855",null,null,"rs5112-G","rs5112",0,5112,"non_coding_transcript_exon_variant",0,0.535,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(Tumor protein p53-inducible protein 11, TP53I11.13022.20.3)",0.23,"[0.17-0.29] unit increase","Affymetrix [10572788] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Glomerular filtration rate","143,658 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.03167,"[0.024-0.039] unit decrease novel","Illumina [6108953] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.889,{"v":4e-17,"d":"4.00E-17"},16.397940008672,"(East Asian)",0.193,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126486409,"rs17321515","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-G","rs17321515",0,17321515,"intron_variant",0,0.49,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.08,"[0.06-0.10] unit decrease","Affymetrix [389878]","N"]
[26,"rs2266788",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Metabolic syndrome","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,1.28,"[1.20-1.36]","Illumina [4642479] (imputed)","N"]
[26,"rs12791103",11,116665079,"rs9804646","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-C","rs9804646",0,9804646,"intergenic_variant",1,0.911,{"v":4e-17,"d":"4.00E-17"},16.397940008672,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2016-09-12",26421299,"Li J","2015-09-03","Biomed Res Int","www.ncbi.nlm.nih.gov/pubmed/26421299","Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort.","Cingulate cortical amyloid beta load","215 European ancestry early mild cognitive impairment cases, 152 European ancestry late mild cognitive impairment cases, 45 European ancestry Alzheimer disease cases, 190  European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-17,"d":"5.00E-17"},16.3010299956639,{"$nulls":3},"Illumina [582718]","N"]
[5,"rs668948",2,21286057,"rs515135","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.1837,{"v":6e-17,"d":"6.00E-17"},16.2218487496163,null,0.0555,"[0.043-0.068] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.704,{"v":6e-17,"d":"6.00E-17"},16.2218487496163,"(Hispanic)",0.124,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.11,{"v":7e-17,"d":"7.00E-17"},16.1549019599857,"(Asian initial, BMI unadjusted)",0.117,"[0.09-0.144] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[27,"rs7970695",12,121424861,"rs7310409","2008-06-22",18439548,"Ridker PM","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439548","Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.","C-reactive protein","6,345 European ancestry female individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-A","rs7310409",0,7310409,"intron_variant",0,"NR",{"v":7e-17,"d":"7.00E-17"},16.1549019599857,null,0.15,"[NR] mg/dl decrease","Illumina [336108]","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":7e-17,"d":"7.00E-17"},16.1549019599857,"(Transmembrane protein 59-like, TMEM59L.9959.60.3)",0.21,"[0.15-0.27] unit increase","Affymetrix [10572788] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":8e-17,"d":"8.00E-17"},16.096910013008,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":8e-17,"d":"8.00E-17"},16.096910013008,null,0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.88,{"v":9e-17,"d":"9.00E-17"},16.0457574905606,"(Asian initial, BMI unadjusted)",0.11,"[0.085-0.135] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[6,"rs1260326",2,27752463,"rs11127048","2017-10-17",28937693,"Clarke TK","2017-07-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28937693","Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).","Alcohol consumption","59,088 European ancestry females, 53,029 European ancestry males","NA","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,5912,7790,"rs11127048-G","rs11127048",0,11127048,"regulatory_region_variant",1,0.38,{"v":1e-16,"d":"1.00E-16"},16,"(women)",0.035,"[0.027-0.043] unit decrease","Affymetrix [12489781] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs13702-A","rs13702",0,13702,"3_prime_UTR_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.29,"[0.23-0.35] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.704,{"v":1e-16,"d":"1.00E-16"},16,"(Hispanic)",0.111,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.41,"[0.31-0.51] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[26,"rs6589567",11,116670676,"rs6589567","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","ZNF259","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,7540,13244,"rs6589567-A","rs6589567",0,6589567,"intergenic_variant",1,0.23,{"v":1e-16,"d":"1.00E-16"},16,"(Indian)",13.09,"[9.99-16.19] unit increase","Illumina [551825]","N"]
[32,"rs112557952",17,43836953,"rs56214516","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling fed-up","374,971 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs56214516-A","rs56214516",0,56214516,"intron_variant",0,0.189219,{"v":1e-16,"d":"1.00E-16"},16,null,8.27,"z score decrease","NR [10847151] (imputed)","N"]
[35,"rs58542926",19,19366632,"rs72999033","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19p13.11","CILP","HAPLN4, AC138430.1, AC138430.2",null,null,"ENSG00000187664, ENSG00000267629, ENSG00000280282",null,null,"rs72999033-T","rs72999033",0,72999033,"3_prime_UTR_variant",0,0.06,{"v":1e-16,"d":"1.00E-16"},16,"(Total cholesterol in medium VLDL)",0.18,"[0.14-0.22] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[37,"rs6129624",20,39154095,"rs6016373","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,399098,160393,"rs6016373-A","rs6016373",0,6016373,"intergenic_variant",1,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Blood sugar levels","93,146 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.03854,"[0.029-0.048] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2017-07-06",28452372,"Gorski M","2017-04-28","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28452372","1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.","Glomerular filtration rate (creatinine)","110,517 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.0081,"[0.0063-0.0099] unit increase","Affymetrix, Illumina [up to 10971307] (imputed)","N"]
[6,"rs13013484",2,27995781,"rs3736594","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","2p23.2","MRPL33","MRPL33",null,null,"ENSG00000243147",null,null,"rs3736594-A","rs3736594",0,3736594,"intron_variant",0,0.2727,{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.0222,"[0.017-0.027] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[9,"5:131664516_TTATATA_T",5,131722951,"rs274555","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","5q31.1","NR","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274555-?","rs274555",0,274555,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.18633,"[0.14-0.23] unit decrease","Affymetrix [7794483] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2013-01-31",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity change in response to statin therapy","2,673 European ancestry cases, 2,656 European ancestry controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.05,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(percent change)",4.8,"[0.82-2.78] percent increase","Illumina [796174]","N"]
[26,"rs2266788",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-A","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.41,"[0.31-0.51] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,43719143,"rs393152","2009-12-10",19915575,"Simon-Sanchez J","2009-11-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19915575","Genome-wide association study reveals genetic risk underlying Parkinson's disease.","Parkinson's disease","1,713 European ancestry cases, 3,978 European ancestry controls","3,361 European ancestry cases, 4,573 European ancestry controls","17q21.31","MAPT, C17orf69, KIAA1267, LOC644246","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs393152-A","rs393152",0,393152,"non_coding_transcript_exon_variant",0,0.82,{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,1.3,"[NR]","Illumina [463185]","N"]
[33,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.163,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19366632,"rs72999033","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"HAPLN4, AC138430.1, AC138430.2",null,null,"ENSG00000187664, ENSG00000267629, ENSG00000280282",null,null,"rs72999033-?","rs72999033",0,72999033,"3_prime_UTR_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs7246100",19,45436216,"rs7260330","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,1573,9279,"rs7260330-G","rs7260330",0,7260330,"intergenic_variant",1,0.39,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(RAC-beta serine/threonine-protein kinase, AKT2.14685.17.3)",0.24,"[0.18-0.3] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.174,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Hispanic)",0.161,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs6882345",5,156380067,"rs4704727","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","5q33.3","TIMD4","TIMD4",null,null,"ENSG00000145850",null,null,"rs4704727-T","rs4704727",0,4704727,"intron_variant",0,0.313,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Trans-ethnic initial)",0.0289,"[0.022-0.036] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[10,"rs6882345",5,156394518,"rs11745603","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,4252,61906,"rs11745603-?","rs11745603",0,11745603,"intergenic_variant",1,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.04524,"[0.034-0.056] unit increase novel","Illumina [6108953] (imputed)","N"]
[16,"rs62466318",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.03656896,"[0.028-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.891,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(East Asian)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglycerides","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.245,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Filipino)",0.342,"unit increase","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[29,"rs139974673",15,44266730,"rs138570705","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs138570705-G","rs138570705",0,138570705,"intron_variant",0,0.971,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(EA)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21319016,"rs672889","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,52071,27773,"rs672889-G","rs672889",0,672889,"intergenic_variant",1,0.1356,{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.1294899,"[0.098-0.161] mg/dl increase","Illumina [24111857] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-03-27",27798624,"Eppinga RN","2016-10-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27798624","Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality.","Resting heart rate","127,919 European ancestry individuals, 2,478 Asian ancestry individuals, 1,734 Black individuals, 684 Mixed ancestry individuals, 1,436 individuals","130,795 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.2746,"[0.21-0.34] unit decrease","Affymetrix [19941912] (imputed)","N"]
[11,"rs147662640",6,28268824,"rs33932084","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","6p22.1","HIST1H4J, ZKSCAN3, OR2B2, HIST1H2BL, HIST1H2AI, HIST1H4K, HIST1H2BPS2, HIST1H1B, HIST1H3I, HIST1H4L, OR2B8P, OR2B7P, ZSCAN12P1, ZNF165, RP1-265C24.5, ZNF192P1, AL022393.7, ZSCAN26, ZSCAN31, ZSCAN23, GPX6, PGBD1, ZSCAN12, HIST1H4PS1, AL009179.1, HIST1H3H, AL049822.1, HIST1H2AJ, HIST1H2BM, Z98744.1, HIST1H2BN, HIST1H2AK, HIST1H2AL, Z98744.2, HIST1H2BO, HIST1H2AM, RNU7-26P, OR2W6P, RPLP2P1, OR2W4P, OR2W2P, OR1F12, ZSCAN16-AS1, ZSCAN16, ZKSCAN8, AL022393.9, ZNF192P2, TOB2P1, ZSCAN9, NKAPL, RP5-874C20.8, RP5-874C20.7, RP5-874C20.6, COX11P1, ZBED9, LINC00533, AL121932.1, RPSAP2, NOP56P1","PGBD1",null,null,"ENSG00000137338",null,null,"rs33932084-G","rs33932084",0,33932084,"missense_variant",0,0.07502518,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(EA, MHC class I polypeptide-related sequence B)",0.6718,"[0.51-0.83] unit decrease","Affymetrix [509946]","N"]
[30,"rs261290",15,58683366,"rs1532085","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(IDL.total, fasting)",0.112,"[NR] unit increase","Illumina [335603]","N"]
[30,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(EA)",0.043,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1728918",2,27635463,"rs1728918","2013-02-12",23128233,"Jostins L","2012-11-01","Nature","www.ncbi.nlm.nih.gov/pubmed/23128233","Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.","Crohn's disease","Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls","Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls","2p23.3","UCN","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-A","rs1728918",0,1728918,"regulatory_region_variant",1,0.299,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,1.123,"[1.086-1.16]","Affymetrix, Illumina [1230000] (imputed)","N"]
[22,"rs538711822",10,65315800,"rs7919685","2018-08-13",29892015,"Roselli C","2018-06-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29892015","Multi-ethnic genome-wide association study for atrial fibrillation.","Atrial fibrillation","55,114 European ancestry cases, 482,295 European ancestry controls, 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls, 1,307 African American ancestry cases, 7,660 African American ancestry controls, 845 Hispanic cases, 4,177 Hispanic controls","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs7919685-G","rs7919685",0,7919685,"intron_variant",0,0.53,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,1.06,"[1.04-1.07]","Affymetrix, Illumina [up to 12149979] (imputed)","N"]
[32,"rs16940904",17,43964539,"rs62055544","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling fed-up","374,971 European ancestry individuals","NA","17q21.31","NR","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs62055544-A","rs62055544",0,62055544,"intron_variant",0,0.216596,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,8.1,"z score decrease","NR [10847151] (imputed)","N"]
[33,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(EA)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65104500,"rs7896518","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FEV1/FVC)","approximately 370,000 European ancestry individuals","NA","10q21.3",null,"JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-?","rs7896518",0,7896518,"intron_variant",0,"NR",{"v":6e-16,"d":"6.00E-16"},15.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,43728376,"rs417968","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Educational attainment (years of education)","approximately 455,000 European ancestry individuals","NA","17q21.31",null,"LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs417968-?","rs417968",0,417968,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-16,"d":"6.00E-16"},15.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[9,"5:131664516_TTATATA_T",5,131590534,"rs7727544","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","P4HA2",null,null,"ENSG00000072682",null,null,"rs7727544-T","rs7727544",0,7727544,"intron_variant",0,0.56,{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(propionylcarnitine)",0.015,"[0.011-0.019] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[9,"rs200800380",5,131665378,"rs272889","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272889-A","rs272889",0,272889,"intron_variant",0,0.37,{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(isovalerylcarnitine + 7 other traits)",0.084,"[NR] unit increase","Affymetrix, Illumina [534665]","N"]
[26,"rs2266788",11,116639104,"rs10790162","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,null,0.39,"[0.29-0.49] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(HDL-C.by.NMR, whole)",1.513,"[NR] unit decrease","Illumina [335603]","N"]
[9,"rs10075801",5,131677642,"rs10075801","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","5q31.1","AC034220.3, SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs10075801-G","rs10075801",0,10075801,"intron_variant",0,0.4855,{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.02915474,"[0.022-0.036] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"rs62466318",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.03591725,"[0.027-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.38,{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,2.719,"[2.07-3.37] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.178,{"v":1e-15,"d":"1.00E-15"},15,"(Hispanic)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.617,{"v":1e-15,"d":"1.00E-15"},15,null,1.06,"[1.04-1.07]","Affymetrix, Illumina [247470]","N"]
[6,"rs13013484",2,27995781,"rs3736594","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","2p23.2","MRPL33","MRPL33",null,null,"ENSG00000243147",null,null,"rs3736594-A","rs3736594",0,3736594,"intron_variant",0,0.2685,{"v":1e-15,"d":"1.00E-15"},15,null,{"v":0.0009176,"d":"9.18E-04"},"[-0.00028-0.00212] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[23,"rs4418728",10,94839724,"rs4418728","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,2077,26905,"rs4418728-T","rs4418728",0,4418728,"TF_binding_site_variant",1,0.4534,{"v":1e-15,"d":"1.00E-15"},15,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[25,"rs72997616",11,75473715,"rs1806895","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","11q13.5","NR","DGAT2, AP001922.1",null,null,"ENSG00000062282, ENSG00000247867",null,null,"rs1806895-T","rs1806895",0,1806895,"intron_variant",0,0.8558,{"v":1e-15,"d":"1.00E-15"},15,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[31,"rs72789541",16,15131974,"rs1136001","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","16p13.11","PDXDC1, NTAN1, C16orf45, KIAA0430, MYH11, NDEI, RRN3, PARN","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs1136001-T","rs1136001",0,1136001,"missense_variant",0,0.309,{"v":1e-15,"d":"1.00E-15"},15,null,0.35,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,0.164,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11208009",1,63199936,"rs6679002","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","1p31.3","ANGPTL3","AC103923.1 - ATG4C","ENSG00000235545","ENSG00000125703",null,23571,49870,"rs6679002-T","rs6679002",0,6679002,"TF_binding_site_variant",1,0.59,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(X-03094)",0.014,"[0.01-0.018] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[6,"rs780110",2,27716494,"rs704795","2018-02-21",26414677,"Day FR","2015-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26414677","Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.","Menopause (age at onset)","up to 69,626 European ancestry women","NA","2p23.3","BRE, GTF3C2, EIFB4","FNDC4",null,null,"ENSG00000115226",null,null,"rs704795-A","rs704795",0,704795,"intron_variant",0,0.4,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.16,"[0.12-0.2] years decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[9,"rs200800380",5,131656700,"rs270602","2016-06-01",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Acylcarnitine levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","5q31.1","SLC22A4, SLC22A5","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs270602-T","rs270602",0,270602,"intron_variant",0,0.3826,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Acetylcarnitine)",0.0505,"[0.038-0.063] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[11,"rs147662640",6,28089731,"rs66886492","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","6p22.1","ZSCAN16-AS1","ZSCAN16-AS1",null,null,"ENSG00000269293",null,null,"rs66886492-T","rs66886492",0,66886492,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,7.943,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.75,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Hispanic)",0.124,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs139857231",11,117002403,"rs6589598","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","PCSK7","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,12506,3841,"rs6589598-G","rs6589598",0,6589598,"intergenic_variant",1,0.77765625,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(TFRC)",0.22989437,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44364649,"rs2696497","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling fed-up","374,971 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2696497-T","rs2696497",0,2696497,"intron_variant",0,0.21384,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,7.92,"z score increase","NR [10847151] (imputed)","N"]
[33,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11882123",19,19552413,"rs4808955","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","19p13.11","GATAD2A","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808955-C","rs4808955",0,4808955,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.0331526,"[0.025-0.041] unit decrease","Affymetrix [16832071] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.232,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Beta-1,3-N-acetylglucosaminyltransferase radical fringe, RFNG.7203.125.3)",0.23,"[0.17-0.29] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Inactive peptidyl-prolyl cis-trans isomerase FKBP6, FKBP6.12529.32.3)",0.21,"[0.15-0.27] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2010-05-26",20442857,"Suchindran S","2010-04-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20442857","Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.","Lipoprotein-associated phospholipase A2 activity and mass","6,668 European ancestry individuals","NA","1p13.3","PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.22,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(activity)",5.5,"[NR] nmol/ml/min decrease","Affymetrix [360811]","N"]
[11,"rs147662640",6,28089731,"rs66886492","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Depressive symptoms","1,067,913 European ancestry individuals","228,033 European ancestry individuals","6p22.1","NR","ZSCAN16-AS1",null,null,"ENSG00000269293",null,null,"rs66886492-T","rs66886492",0,66886492,"non_coding_transcript_exon_variant",0,0.101180196330638,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.017245498,"[0.013-0.022] unit decrease","NR [NR]","N"]
[16,"7:73042302_GCTTT_G",7,72864869,"rs714052","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-G","rs714052",0,714052,"intron_variant",0,0.12,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.16,"[0.10-0.22] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[22,"rs538711822",10,65062008,"rs10761739","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761739-C","rs10761739",0,10761739,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.023315772,"[0.018-0.029] unit increase","Affymetrix [NR]","N"]
[27,"rs7970695",12,121420263,"rs7979478","2019-03-25",30589442,"Whitfield JB","2018-12-27","Alcohol Clin Exp Res","www.ncbi.nlm.nih.gov/pubmed/30589442","Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers.","Gamma glutamyl transferase levels in low alcohol consumption","8,716 individuals","NA","12q24.31","NR","HNF1A",null,null,"ENSG00000135100",null,null,"rs7979478-?","rs7979478",0,7979478,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.035,"[0.026-0.044] unit decrease","Illumina [~ 7800000] (imputed)","N"]
[32,"rs16940904",17,43569909,"rs146746174","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Self-reported math ability (MTAG)","670,471 European ancestry individuals","NA","17q21.31","Intergenic","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,1794,14198,"rs146746174-T","rs146746174",1,62065449,"intergenic_variant",1,0.8153,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(MTAG)",0.0182,"[0.014-0.023] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[32,"rs16940904",17,44347218,"rs2696557","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling nervous","373,121 European ancestry individuals","NA","17q21.31","NR","AC005829.1 - ARL17B","ENSG00000261575","ENSG00000228696",null,1158,4932,"rs2696557-A","rs2696557",0,2696557,"intergenic_variant",1,0.214201,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,7.91,"z score increase","NR [10847151] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680954,"rs2043085","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043085-?","rs2043085",0,2043085,"intron_variant",0,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",1.1494253,null,"Illumina [12023830] (imputed)","N"]
[32,"rs35076622",17,43854655,"rs34186148","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs34186148-C","rs34186148",0,34186148,"intron_variant",0,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,null,7.869,"z score increase","Affymetrix [10847151] (imputed)","N"]
[4,"rs629301",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,29372323,"rs429479","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","6p22.1","OR5V1","OR5V1, OR5V1, OR5V1, OR5V1, OR5V1",null,null,"ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000112461, ENSG00000243441",null,null,"rs429479-A","rs429479",0,429479,"intron_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,7.818,"z-score decrease","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2014-03-01",23903356,"Hayes MG","2013-07-31","Diabetes","www.ncbi.nlm.nih.gov/pubmed/23903356","Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.","Glycemic traits (pregnancy)","1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean individuals, 1,178 Thai ancestry individuals","2,798 European ancestry individuals, 228 French Canadian founder population individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.91,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(FCP)",0.0294,"[NR] unit decrease","Illumina [up to 945994] (imputed)","N"]
[18,"rs7819706",8,19849757,"rs17091905","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,24987,86868,"rs17091905-A","rs17091905",0,17091905,"intergenic_variant",1,0.12,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(TRIG)",0.174,"[0.13-0.22] mmol/l decrease","Illumina [NR] (imputed)","N"]
[31,"rs11644601",16,15150505,"rs12928099","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16p13.11","intergenic","PDXDC1",null,null,"ENSG00000179889",null,null,"rs12928099-A","rs12928099",0,12928099,"intron_variant",0,0.2698,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.0253,"[0.019-0.032] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[33,"rs77535126",18,47118923,"rs3786247","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs3786247-T","rs3786247",0,3786247,"3_prime_UTR_variant",0,0.6,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(BMI unadjusted)",0.106,"[0.081-0.131] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[36,"rs429358",19,45424351,"rs814573","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,1745,5710,"rs814573-T","rs814573",0,814573,"intergenic_variant",1,0.198,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(Apolipoprotein E (isoform E2), APOE.5312.49.3)",0.25,"[0.19-0.31] unit increase","Affymetrix [10572788] (imputed)","N"]
[11,"rs147662640",6,28268824,"rs33932084","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Pulse pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","6p22.1","PGBD1","PGBD1",null,null,"ENSG00000137338",null,null,"rs33932084-G","rs33932084",0,33932084,"missense_variant",0,0.9087,{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.3397,"[0.25-0.43] mmHg decrease","Affymetrix [NR] (imputed)","N"]
[32,"rs16940904",17,43810896,"rs77804065","2018-03-01",29397368,"Meng W","2018-01-31","EBioMedicine","www.ncbi.nlm.nih.gov/pubmed/29397368","A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).","Headache","74,461 British ancestry cases, 149,321 British ancestry controls","NA","17q21.31","LINC02210, CRHR1, MAPT","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,"NR",{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.013,"[0.0097-0.0163] unit increase","Affymetrix [9304965] (imputed)","N"]
[32,"rs16940904",17,43940021,"rs79412431","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","Peak expiratory flow","321,047 European ancestry individuals","24,218 European ancestry individuals","17q21.31","MAPT-AS1","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs79412431-A","rs79412431",0,79412431,"intron_variant",0,0.2161,{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.0239,"[0.018-0.03] unit decrease","Affymetrix [19819130] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2008-06-22",18439548,"Ridker PM","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439548","Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.","C-reactive protein","6,345 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-A","rs780094",0,780094,"intron_variant",0,"NR",{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.14,"[NR] mg/dl increase","Illumina [336108]","N"]
[9,"rs10075801",5,131466629,"rs3843503","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","Lung function (FVC)","321,047 European ancestry individuals","79,005 European ancestry individuals","5q31.1","P4HA2-AS1","RF00285 - AC063976.3","ENSG00000264452","ENSG00000227616",null,50803,16555,"rs3843503-A","rs3843503",0,3843503,"intergenic_variant",1,0.4482,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.0187,"[0.014-0.023] unit decrease","Affymetrix [19819130] (imputed)","N"]
[33,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,0.17,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.17,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.14,"[0.10-0.18] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[3,"rs1167998",1,62950858,"rs10889332","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889332-?","rs10889332",0,10889332,"3_prime_UTR_variant",0,0.29,{"v":8e-15,"d":"8.00E-15"},14.096910013008,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.86,{"v":8e-15,"d":"8.00E-15"},14.096910013008,"(X-03094)",0.025,"[0.019-0.031] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[32,"rs16940904",17,44187257,"rs9303525","2012-06-01",22504418,"Ikram MA","2012-04-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22504418","Common variants at 6q22 and 17q21 are associated with intracranial volume.","Intracranial volume","8,175 European ancestry individuals","1,752 European ancestry individuals","17q21.31","MAPT, GRN, CRHR1, STH","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs9303525-G","rs9303525",0,9303525,"intron_variant",0,0.22,{"v":8e-15,"d":"8.00E-15"},14.096910013008,null,14.9,"[NR] ml decrease","Affymetrix, Illumina [2229753] (imputed)","N"]
[9,"rs200800380",5,131665378,"rs272889","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","5q31.1","SLC22A4, SLC22A5","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272889-?","rs272889",0,272889,"intron_variant",0,"NR",{"v":9e-15,"d":"9.00E-15"},14.0457574905606,"(isovalerylcarnitine)",0.04099,"[NR] unit increase","Affymetrix [655658]","N"]
[19,"rs2954021",8,126482077,"rs2954021","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte percentage of white cells","171,748 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5053,{"v":9e-15,"d":"9.00E-15"},14.0457574905606,null,0.02756497,"[0.021-0.035] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":9e-15,"d":"9.00E-15"},14.0457574905606,"(HDL-C.assay, fasting)",1.421,"[NR] unit increase","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.617,{"v":1E-14,"d":"1.00E-14"},14,null,1.05,"[1.04-1.07]","Affymetrix, Illumina [247470]","N"]
[18,"rs15285",8,19820405,"rs331","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs331-?","rs331",0,331,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,"(HDL-C.by.NMR, whole)",1.21,"[NR] unit increase","Illumina [335603]","N"]
[19,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs56068105",10,5254847,"rs1832007","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","10p15.1","AKR1C4","AKR1C4",null,null,"ENSG00000198610",null,null,"rs1832007-A","rs1832007",0,1832007,"intron_variant",0,0.868,{"v":1E-14,"d":"1.00E-14"},14,"(Trans-ethnic initial)",0.0327,"[0.023-0.042] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.49,{"v":1E-14,"d":"1.00E-14"},14,"(HDL)",0.14,"[0.1-0.18] unit decrease","Illumina [561583]","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.825,{"v":1E-14,"d":"1.00E-14"},14,"(AA)",0.252,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":1E-14,"d":"1.00E-14"},14,"(Stromal interaction molecule 1, STIM1.9271.101.3)",0.26,"[0.2-0.32] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2014-03-22",24023261,"Keller M","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023261","THOC5: a novel gene involved in HDL-cholesterol metabolism.","Lipid traits","839 European ancestry individuals","up to 5,248 European ancestry individuals","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":1E-14,"d":"1.00E-14"},14,"(LDL-C)",0.25,"unit increase","Affymetrix [390619]","N"]
[18,"rs76722925",8,19819724,"rs328","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(HDL)",0.04,"[0.020-0.060] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[22,"rs538711822",10,65315800,"rs7919685","2018-08-13",29892015,"Roselli C","2018-06-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29892015","Multi-ethnic genome-wide association study for atrial fibrillation.","Atrial fibrillation","55,114 European ancestry cases, 482,295 European ancestry controls, 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls, 1,307 African American ancestry cases, 7,660 African American ancestry controls, 845 Hispanic cases, 4,177 Hispanic controls","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs7919685-G","rs7919685",0,7919685,"intron_variant",0,0.52,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(EA)",1.06,"[1.04-1.08]","Affymetrix, Illumina [up to 12149979] (imputed)","N"]
[30,"rs1077835",15,58723426,"rs1077835","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.38,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.17,"[0.13-0.21] unit decrease","Illumina [1361436] (imputed)","N"]
[30,"rs1077835",15,58723426,"rs1077835","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-G","rs1077835",0,1077835,"intron_variant",0,0.22,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.059,"[0.043-0.075] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[38,"rs4818005",21,40574305,"rs2183573","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","21q22.2","BRWD1","BRWD1",null,null,"ENSG00000185658",null,null,"rs2183573-A","rs2183573",0,2183573,"missense_variant",0,0.4103,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.0158,"[0.012-0.02] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum albumin level","Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.0124,"[0.0093-0.0155] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-11-25",26831199,"Pattaro C","2016-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26831199","Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.","Glomerular filtration rate (creatinine)","133,413 European ancestry individuals","42,166 European ancestry individuals, up to 16,471 African ancestry individuals, up to 42,296 Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.42,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.0068,"[0.005-0.0086] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[18,"rs15285",8,19820405,"rs331","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs331-?","rs331",0,331,"intron_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(HDL-C.assay, fasting)",1.51,"[NR] unit increase","Illumina [335603]","N"]
[18,"rs76722925",8,19928582,"rs9644568","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103812,8043,"rs9644568-A","rs9644568",0,9644568,"intergenic_variant",1,0.254704,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.12829615,"[0.095-0.161] mg/dl increase","Illumina [24111857] (imputed)","N"]
[32,"rs16940904",17,43923683,"rs12185268","2011-07-20",21738487,"Do CB","2011-06-23","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21738487","Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.","Parkinson's disease","3,426 European ancestry cases, 29,624 European ancestry controls","NA","17q21.31","MAPT","MAPT-AS1, MAPT-AS1, MAPT-AS1, SPPL2C, SPPL2C, SPPL2C",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000277106, ENSG00000185294, ENSG00000278194",null,null,"rs12185268-A","rs12185268",0,12185268,"missense_variant",0,0.79,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,1.3,"[1.22-1.39]","Illumina [522782]","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.885,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(Hispanic)",0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.178,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.147,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.175,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.148,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs673335",11,75450576,"rs673335","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","11q13.5",null,"MOGAT2 - RN7SL786P","ENSG00000166391","ENSG00000263993",null,6573,2598,"rs673335-?","rs673335",0,673335,"intergenic_variant",1,"NR",{"v":4E-14,"d":"4.00E-14"},13.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs143875230",15,43099550,"rs149492745","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.2","NR","TTBK2",null,null,"ENSG00000128881",null,null,"rs149492745-C","rs149492745",0,149492745,"intron_variant",0,0.973,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(EA)",0.091,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11210912,"rs2228671","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs2228671-G","rs2228671",0,2228671,"stop_gained",0,0.88,{"v":4E-14,"d":"4.00E-14"},13.397940008672,null,0.14,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[36,"rs5112",19,45430280,"rs5112","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1P1","APOC1P1",null,null,"ENSG00000214855",null,null,"rs5112-G","rs5112",0,5112,"non_coding_transcript_exon_variant",0,0.535,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Pregnancy-specific beta-1-glycoprotein 5, PSG5.9314.9.3)",0.2,"[0.14-0.26] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs1167998",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136806959,"rs925966","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","2q21.3",null,"DARS-AS1 - AC068492.1","ENSG00000231890","ENSG00000237262",null,26796,28503,"rs925966-?","rs925966",0,925966,"intergenic_variant",1,"NR",{"v":5e-14,"d":"5.00E-14"},13.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs2266788",11,116652423,"rs6589566","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","11q23.3","APOC, APOA","ZPR1",null,null,"ENSG00000109917",null,null,"rs6589566-C","rs6589566",0,6589566,"intron_variant",0,0.0176,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(AA)",0.2066,"[NR] unit increase","Affymetrix [NR]","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.914,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(Hispanic)",0.201,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1183851",1,62902874,"rs646179","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","1p31.3",null,"USP1",null,null,"ENSG00000162607",null,null,"rs646179-?","rs646179",0,646179,"5_prime_UTR_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,0.758,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(EA)",0.042,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(APOA1.assay, whole)",2.529,"[NR] unit decrease","Illumina [335603]","N"]
[36,"rs157595",19,45414451,"rs439401","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-?","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,null,1.486781,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,0.485,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(EA)",0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs12791103",11,116665079,"rs9804646","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-C","rs9804646",0,9804646,"intergenic_variant",1,0.793,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(East Asian)",0.125,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs688456",11,116728630,"rs12225230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs12225230-G","rs12225230",0,12225230,"missense_variant",0,0.823,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(EA)",0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.891,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,"(East Asian)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"19:19510831_AT_A",19,19591066,"rs10401193","2015-09-24",25282103,"Wood AR","2014-10-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25282103","Defining the role of common variation in the genomic and biological architecture of adult human height.","Height","253,288 European ancestry individuals","80,067 European ancestry individuals","19p13.11","GATAD2A","GATAD2A",null,null,"ENSG00000167491",null,null,"rs10401193-A","rs10401193",0,10401193,"intron_variant",0,0.819,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,null,0.028,"[0.02-0.036] unit increase","Affymetrix, Illumina, Perlegen [2550858] (imputed)","N"]
[3,"rs1167998",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-04-30",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Low density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.27,{"v":1E-13,"d":"1.00E-13"},13,"(Indian)",5.26,"[3.87-6.65] unit decrease","Illumina [551825]","N"]
[5,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.177,{"v":1E-13,"d":"1.00E-13"},13,"(Hispanic)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-A","rs7570971",0,7570971,"intron_variant",0,0.35,{"v":1E-13,"d":"1.00E-13"},13,null,0.03,"[NR] unit increase","NR [NR] (imputed)","N"]
[11,"rs147662640",6,27912724,"rs547190239","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Diastolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","6p22.1","intergenic","OR2W6P - OR2B6","ENSG00000168126","ENSG00000124657",null,6543,12295,"rs547190239-G","rs547190239",1,78669424,"intergenic_variant",1,0.6504,{"v":1E-13,"d":"1.00E-13"},13,null,0.326,"[0.24-0.41] mmHg increase","Affymetrix [NR] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1045,{"v":1E-13,"d":"1.00E-13"},13,null,0.0312,"[0.022-0.041] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[32,"rs546735951",17,43488792,"rs62064641","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","17q21.31",null,"ARHGAP27, ARHGAP27, ARHGAP27",null,null,"ENSG00000276836, ENSG00000276907, ENSG00000159314",null,null,"rs62064641-?","rs62064641",0,62064641,"intron_variant",0,"NR",{"v":1E-13,"d":"1.00E-13"},13,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs3761077",19,19336608,"rs2238675","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.887,{"v":1E-13,"d":"1.00E-13"},13,"(Hispanic)",0.164,"[0.12-0.21] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid t-tau levels in mild cognitive impairment","581 European ancestry cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":1E-13,"d":"1.00E-13"},13,null,0.57,"[0.41-0.73] unit increase","Illumina [8449920] (imputed)","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.674,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.748,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(AA)",0.218,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Total cholesterol levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4253,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.0656419,"[0.78-1.35] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.89,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(East Asian)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65138910,"rs7910927","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7910927-T","rs7910927",0,7910927,"intron_variant",0,0.51,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(Women)",0.046,"[0.034-0.058] umol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[24,"rs55891451",10,96750543,"rs4918798","2016-08-17",26265036,"Parra EJ","2015-08-12","Pharmacogenomics","www.ncbi.nlm.nih.gov/pubmed/26265036","Genome-wide association study of warfarin maintenance dose in a Brazilian sample.","Warfarin maintenance dose","180 Brazilian ancestry low dose individuals, 187 Brazilian ancestry high dose individuals","798 European ancestry individuals, 1611 Japanese ancestry individuals, 191 African American individuals","10q23.33","CYP2C9","CYP2C9 - CYP2C59P","ENSG00000138109","ENSG00000228460",null,1395,16340,"rs4918798-C","rs4918798",0,4918798,"intergenic_variant",1,null,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(Brazilian)",6.22,null,"Affymetrix [> 650000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8775,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(NXPH2)",0.27592963,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[26,"rs2266788",11,116652423,"rs6589566","2017-05-15",28046027,"Kim T","2017-01-03","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28046027","Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup.","Triglyceride to HDL cholesterol ratio","5,292 Korean ancestry individuals","2,567 Korean ancestry individuals","11q23.3","APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs6589566-?","rs6589566",0,6589566,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,2.078E-3,"[0.0015-0.0026] unit increase","Affymetrix [310746]","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs199460",17,44788310,"rs183211","2015-12-18",25581431,"Kuchenbaecker KB","2015-01-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25581431","Identification of six new susceptibility loci for invasive epithelial ovarian cancer.","Epithelial ovarian cancer","4,368 European ancestry cases, 9,123 European ancestry controls,","2,462 European ancestry BRCA1 mutation carrier cases, 12,790 European ancestry BRCA1 mutation carrier controls, up to 631 European ancestry BRCA2 mutation carrier cases, 7,580 European ancestry BRCA2 mutation carrier controls, 9,627 European ancestry serous cases, 1,442 European ancestry non-serous cases, 21,722 European ancestry controls","17q21.31","PLEKHM1","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs183211-A","rs183211",0,183211,"intron_variant",0,0.24,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.11,"[1.07-1.16]","Illumina [up to 10962898] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.041,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC1, CTB-129P6.7","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.1730382,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA, Apolipoprotein E (isoform E2))",0.4193,"[0.31-0.53] unit increase","Affymetrix [509946]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.36,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.045,"[0.033-0.057] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[11,"rs147662640",6,28793904,"rs3118359","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6p22.1","intergenic","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,42123,11742,"rs3118359-T","rs3118359",0,3118359,"intergenic_variant",1,0.0838,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.0378,"[0.028-0.048] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.917,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Hispanic)",0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.44,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Asian initial, BMI unadjusted)",0.064,"[0.046-0.082] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2018-10-24",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglyceride levels","1,017 Yoruban ancestry individuals, 1,765 Filipino individuals","188,577 European and other ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Filipino)",null,null,"Illumina [4454201] (imputed)","N"]
[26,"rs139857231",11,117002403,"rs6589598","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","PCSK7","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,12506,3841,"rs6589598-G","rs6589598",0,6589598,"intergenic_variant",1,0.77765625,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(CASC4)",0.22286546,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43567337,"rs1879586","2017-08-07",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","High-grade serous ovarian cancer","13,037 European ancestry cases, 40,941 European ancestry controls","NA","17q21.31","NR","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs1879586-G","rs1879586",0,1879586,"intron_variant",0,0.181254,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,1.1585579,"[1.11378456264581-1.20513099189349]","Illumina [11595112] (imputed)","N"]
[32,"rs16940904",17,43919105,"rs2106785","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","ACBD4","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs2106785-T","rs2106785",0,2106785,"non_coding_transcript_exon_variant",0,0.213768,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,7.29,"z score increase","NR [~ 10847151] (imputed)","N"]
[36,"rs429358",19,45396665,"rs59007384","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs59007384-T","rs59007384",0,59007384,"intron_variant",0,0.25,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.11,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[36,"rs429358",19,45418790,"rs5117","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs5117-C","rs5117",0,5117,"intron_variant",0,0.28,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.1,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[3,"rs1167998",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21428289,"rs71435601","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","2p24.1","NR","AC067959.1 - AC018742.1","ENSG00000271629","ENSG00000233005",null,6521,15758,"rs71435601-G","rs71435601",0,71435601,"intergenic_variant",1,0.133847,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,0.11650893,"[0.085-0.148] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.889,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(East Asian)",0.154,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,0.87,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(East Asian)",0.174,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-09-22",25648963,"Debette S","2014-11-25","Biol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25648963","Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.","Verbal declarative memory","Up to 27,337 European ancestry individuals, up to 472 Korkulan individuals, up to 1,267 Erasmus Rucphen Family individuals","Up to 10,617 European ancestry individuals, up to 3,811 African American individuals","19q13.32","PVRL2, TOMM40","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.16,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(PAR-dr)",null,null,"Affymetrix, Illumina [NR] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2015-09-22",25648963,"Debette S","2014-11-25","Biol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25648963","Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.","Verbal declarative memory","Up to 27,337 European ancestry individuals, up to 472 Korkulan individuals, up to 1,267 Erasmus Rucphen Family individuals","Up to 10,617 European ancestry individuals, up to 3,811 African American individuals","19q13.32","PVRL2, TOMM40","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.16,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(PAR-dr, EA)",null,null,"Affymetrix, Illumina [NR] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.041,"[NR] unit increase","NR [NR] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.541,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,1.06,"[1.04-1.08]","Affymetrix [9149595] (imputed)","N"]
[26,"rs56224630",11,116603724,"rs12272004","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,74756,15162,"rs12272004-C","rs12272004",0,12272004,"TF_binding_site_variant",1,0.93,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.18,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[26,"rs964184",11,116648917,"rs964184","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Hispanic)",0.103,"[0.076-0.13] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-C","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.39,"[0.29-0.49] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs1077835",15,58723939,"rs2070895","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-A","rs2070895",0,2070895,"intron_variant",0,0.41,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Asian initial, BMI unadjusted)",0.077,"[0.055-0.099] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-03-01",23903356,"Hayes MG","2013-07-31","Diabetes","www.ncbi.nlm.nih.gov/pubmed/23903356","Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.","Glycemic traits (pregnancy)","1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean individuals, 1,178 Thai ancestry individuals","2,798 European ancestry individuals, 228 French Canadian founder population individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.409,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(FPG)",0.0044,"[NR] unit decrease","Illumina [up to 945994] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.75,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(Hispanic)",0.102,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,44355362,"rs143573049","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","15q15.3",null,"FRMD5",null,null,"ENSG00000171877",null,null,"rs143573049-?","rs143573049",0,143573049,"intron_variant",0,"NR",{"v":6e-13,"d":"6.00E-13"},12.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[29,"rs1561458",15,44408401,"rs2733201","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","15q15.3","FRMD5","FRMD5",null,null,"ENSG00000171877",null,null,"rs2733201-T","rs2733201",0,2733201,"intron_variant",0,0.07311,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,7.3,"[5.32-9.28] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[32,"rs16940904",17,43758787,"rs62055701","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs62055701-A","rs62055701",0,62055701,"intron_variant",0,0.214491,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,7.19,"z score increase","NR [~ 10847151] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2015-09-22",25648963,"Debette S","2014-11-25","Biol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25648963","Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.","Verbal declarative memory","Up to 27,337 European ancestry individuals, up to 472 Korkulan individuals, up to 1,267 Erasmus Rucphen Family individuals","Up to 10,617 European ancestry individuals, up to 3,811 African American individuals","19q13.32","APOC1, APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(ALL-dr, EA)",null,null,"Affymetrix, Illumina [NR] (imputed)","N"]
[21,"rs7084630",10,5138036,"rs2518049","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","10p15.1","AKR1C","AKR1C3",null,null,"ENSG00000196139",null,null,"rs2518049-A","rs2518049",0,2518049,"intron_variant",0,0.175,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(SM-13)",0.07,"[NR] unit decrease","Affymetrix, Illumina [534665]","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity (ABCA-1 dependent assay)","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","11q23.3","APOA1/C3/A4/A5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.857,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,0.2019,"[0.15-0.26] unit increase","Illumina [at least 9000000] (imputed)","N"]
[32,"rs16940904",17,43731719,"rs241036","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Menarche (age at onset)","approximately 242,000 European ancestry individuals","NA","17q21.31",null,"LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs241036-?","rs241036",0,241036,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-13,"d":"7.00E-13"},12.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,44252468,"rs2532263","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2532263-G","rs2532263",0,2532263,"intron_variant",0,0.81,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(EA)",1.0526316,"[1.03-1.08] (Oncoarray)","Illumina [~ 11800000] (imputed)","N"]
[11,"rs147662640",6,29549653,"rs1233393","2018-07-19",29662059,"Howard DM","2018-04-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29662059","Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.","Depression (broad)","113,769 British ancestry cases, 208,811 British ancestry controls","NA","6p22.1","NR","GABBR1, GABBR1, GABBR1, GABBR1, GABBR1, GABBR1, GABBR1",null,null,"ENSG00000232569, ENSG00000206511, ENSG00000204681, ENSG00000232632, ENSG00000237051, ENSG00000206466, ENSG00000237112",null,null,"rs1233393-G","rs1233393",0,1233393,"intron_variant",0,0.1223,{"v":8e-13,"d":"8.00E-13"},12.096910013008,null,0.0129,"[0.0094-0.0164] unit decrease","NR [7666894] (imputed)","N"]
[16,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.81,{"v":8e-13,"d":"8.00E-13"},12.096910013008,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11644601",16,15172118,"rs11644601","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipid measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16p13.11","NPIPA5, PDXC1","RRN3, PDXDC1",null,null,"ENSG00000085721, ENSG00000179889",null,null,"rs11644601-C","rs11644601",0,11644601,"intron_variant",0,0.28,{"v":8e-13,"d":"8.00E-13"},12.096910013008,"(ratio of bis-allylic bonds to double bonds in lipids)",0.1,"[0.08-0.12] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[32,"rs16940904",17,44041107,"rs56280951","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling miserable","376,097 European ancestry individuals","NA","17q21.31","ACBD4","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs56280951-A","rs56280951",0,56280951,"intron_variant",0,0.21432,{"v":8e-13,"d":"8.00E-13"},12.096910013008,null,7.17,"z score increase","NR [10847151] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2013-03-22",23281178,"Hong MG","2013-03-01","Hum Mutat","www.ncbi.nlm.nih.gov/pubmed/23281178","A genome-wide assessment of variability in human serum metabolism.","Metabolite levels","214 European ancestry prostate cancer cases, 188 European ancestry controls","489 European ancestry prostate cancer cases","15q21.3","LIPC","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-C","rs261342",0,261342,"intron_variant",0,"NR",{"v":9E-13,"d":"9.00E-13"},12.0457574905606,"(Glycerophospho-N-Palmitoyl Ethanolamine)",null,null,"Affymetrix [333722]","N"]
[32,"rs16940904",17,44787313,"rs538628","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling nervous","373,121 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs538628-C","rs538628",0,538628,"intron_variant",0,0.206782,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,7.14,"z score increase","NR [10847151] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-?","rs5167",0,5167,"missense_variant",0,"NR",{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,0.03734,"[0.027-0.048] unit decrease novel","Illumina [6108953] (imputed)","N"]
[3,"rs1167998",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,"(VLDL.total, fasting)",2.688,"[NR] unit decrease","Illumina [335603]","N"]
[11,"rs147662640",6,28796071,"rs116461399","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer","29,266 European ancestry cases, 56,450 European ancestry controls","NA","6p22.1","ZBED9, LINC01623","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,44290,9575,"rs116461399-C","rs116461399",1,3131337,"regulatory_region_variant",1,0.095879119,{"v":1e-12,"d":"1.00E-12"},12,null,1.1547382,"[1.109954181-1.20132906]","Illumina [10439017] (imputed)","N"]
[11,"rs147662640",6,29254982,"rs139244745","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer","29,266 European ancestry cases, 56,450 European ancestry controls","NA","6p22.1","OR2J2, OR14J1","AL672167.1",null,null,"ENSG00000197171",null,null,"rs139244745-G","rs139244745",1,9257681,"intron_variant",0,0.094855408,{"v":1e-12,"d":"1.00E-12"},12,null,1.1562266,"[1.110831882-1.203476432]","Illumina [10439017] (imputed)","N"]
[13,"rs186696265",6,161111700,"rs186696265","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","6q26","intergenic","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,0.01809,{"v":1e-12,"d":"1.00E-12"},12,null,12.07,"[8.76-15.38] (nmol/min/ml) increase","Affymetrix, Illumina [13572687] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72856269,"rs2240466","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2240466-G","rs2240466",0,2240466,"3_prime_UTR_variant",0,0.87,{"v":1e-12,"d":"1.00E-12"},12,null,0.14,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[16,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1e-12,"d":"1.00E-12"},12,null,0.17,"[0.11-0.23] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[29,"rs139974673",15,43726625,"rs150844304","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","15q15.3",null,"TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-?","rs150844304",0,150844304,"intron_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,43719143,"rs393152","2016-07-08",26077951,"Kouri N","2015-06-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26077951","Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.","Corticobasal degeneration","152 cases, 3,111 controls","67 cases, 457 controls","17q21.31","MAPT","LINC02210, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000204650, ENSG00000263715, ENSG00000282456",null,null,"rs393152-?","rs393152",0,393152,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,3.7,"[NR]","Illumina [533898] (imputed)","N"]
[32,"rs16940904",17,44096553,"rs62062288","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Automobile speeding propensity","404,291 European ancestry individuals","NA","17q21.31","KANSL1","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.2196,{"v":1e-12,"d":"1.00E-12"},12,null,0.019352188,"[0.014-0.025] unit decrease","Affymetrix [11514463] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2015-05-11",22005931,"Kamboh MI","2011-10-18","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/22005931","Genome-wide association analysis of age-at-onset in Alzheimer's disease.","Alzheimer's disease (age of onset)","1,190 European ancestry cases, 1,032 cases","NA","19q13.32","APOE, TOMM40, APOC1, PVRL2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,2.2018,"unit increase","Illumina [2543888] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.989,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Hispanic)",0.507,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","LDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-T","rs13392272",0,13392272,"intergenic_variant",1,0.387,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Hispanic)",0.095,"[0.068-0.122] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[5,"rs10184054",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2015-11-07",25646370,"Matsuo H","2015-02-02","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/25646370","Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.","Gout","945 Japanese ancestry cases, 1,213 Japanese ancestry controls","1,048 Japanese ancestry cases, 1,334 Japanese ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.55,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,1.36,"[1.25-1.48]","Illumina [570442]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte counts","171,643 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6052,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.02574395,"[0.019-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[10,"rs4704835",5,156442784,"rs1948760","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","5q33.3",null,"TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,52518,13640,"rs1948760-?","rs1948760",0,1948760,"intergenic_variant",1,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[11,"rs147662640",6,28281894,"rs34661125","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer","29,266 European ancestry cases, 56,450 European ancestry controls","NA","6p22.1","PGBD1, ZSCAN31","PGBD1 - AL021997.2","ENSG00000137338","ENSG00000273712",null,11568,1496,"rs34661125-A","rs34661125",0,34661125,"intergenic_variant",1,0.078778393,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,1.1597158,"[1.112709654-1.208707736]","Illumina [10439017] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or ischemic stroke","12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls","NA","6q25.3","SLC22A3, LPAL2, LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-?","rs10455872",0,10455872,"intron_variant",0,null,{"v":2E-12,"d":"2.00E-12"},11.698970004336,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of white cells","171,542 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5053,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.02513768,"[0.018-0.032] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,65104500,"rs7896518","2012-04-03",22423221,"Qayyum R","2012-03-08","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22423221","A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.","Mean platelet volume","16,388 African American individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-A","rs7896518",0,7896518,"intron_variant",0,0.324,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Platelet Count)",5.18,"[3.73-6.63] 10^9 L increase","Affymetrix, Illumina [~ 2200000] (imputed)","N"]
[22,"rs538711822",10,65321147,"rs12245149","2018-10-17",30061737,"Nielsen JB","2018-07-30","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30061737","Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.","Atrial fibrillation","60,620 European ancestry cases, 970,216 European ancestry controls","NA","10q21.3","REEP3, NRBF2","REEP3",null,null,"ENSG00000165476",null,null,"rs12245149-C","rs12245149",0,12245149,"intron_variant",0,0.526,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,1.05,"[1.03-1.06]","Illumina [34740186] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.49,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(East Asian)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3867518",16,15378697,"rs1629212","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","16p13.11","MPV17L, PDXDC1, PLA2G10","AC126763.1 - AC137803.1","ENSG00000257391","ENSG00000277770",null,127820,74138,"rs1629212-A","rs1629212",0,1629212,"intergenic_variant",1,0.5974,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(lysoPhosphatidylcholine acyl C20:3)",0.0493,"[0.036-0.063] unit decrease","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[32,"rs16940904",17,44037491,"rs17650842","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17650842-A","rs17650842",0,17650842,"intron_variant",0,0.21663,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,7.01,"z score decrease","NR [~ 10847151] (imputed)","N"]
[33,"rs9304381",18,47181668,"rs2156552","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-T","rs2156552",0,2156552,"intergenic_variant",1,0.81,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.03,"[0.02-0.04] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.493,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs200800380",5,131714409,"rs274567","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274567-T","rs274567",0,274567,"non_coding_transcript_exon_variant",0,0.37,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(acetylcarnitine)",0.018,"[0.012-0.024] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[13,"rs10455872",6,160997118,"rs74617384","2018-10-16",30003307,"Fall T","2018-07-12","Diabetologia","www.ncbi.nlm.nih.gov/pubmed/30003307","Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.","Coronary artery disease in diabetes","3,968 British ancestry cases, 11,698 British ancestry controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-T","rs74617384",0,74617384,"intron_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,1.38,"[1.26-1.51]","Affymetrix [9087334] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73012042,"rs35332062","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-?","rs35332062",0,35332062,"missense_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.22857,"[0.16-0.29] unit increase","Affymetrix [7794483] (imputed)","N"]
[22,"rs538711822",10,65027610,"rs10761731","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,0.43,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,2.38,"[1.64-3.12] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[23,"rs4418728",10,94839642,"rs2068888","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","10q23.33","CYP26A1","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-A","rs2068888",0,2068888,"regulatory_region_variant",1,0.491,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(Trans-ethnic initial)",0.0241,"[0.017-0.031] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.33,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(HDL)",0.104,"[0.075-0.133] mmol/l increase","Illumina [NR] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.29,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(1-palmitoylglycerophosphoethanolamine)",0.019,"[0.013-0.025] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[32,"rs16940904",17,43573419,"rs62065453","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","PLEKHM1 - LRRC37A4P","ENSG00000277111","ENSG00000282331",null,5304,10688,"rs62065453-T","rs62065453",0,62065453,"intergenic_variant",1,0.217174,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,6.99,"z score increase","NR [~ 10847151] (imputed)","N"]
[32,"rs16940904",17,44326864,"rs2696625","2019-01-18",30531941,"Doherty A","2018-12-10","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30531941","GWAS identifies 14 loci for device-measured physical activity and sleep duration.","Physical activity (overall physical activity time)","91,105 European ancestry individuals","NA","17q21.31","KANSL1-AS1","MAPK8IP1P1 - AC005829.2","ENSG00000281283","ENSG00000262539",null,4454,10053,"rs2696625-A","rs2696625",0,2696625,"intergenic_variant",1,0.77,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.037,"[0.027-0.047] SD units decrease","NR [9926106] (imputed)","N"]
[36,"rs5112",19,45430280,"rs5112","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","19q13.32",null,"APOC1P1",null,null,"ENSG00000214855",null,null,"rs5112-?","rs5112",0,5112,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Palmitoleic acid (16:1n-7) levels","3,521 Chinese ancestry individuals, European individuals (see Wu 2013).","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.019,"[0.013-0.025] unit increase","Affymetrix, Illumina [~ 2200000] (imputed)","N"]
[10,"rs6882345",5,156390297,"rs6882076","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-G","rs6882076",0,6882076,"regulatory_region_variant",1,0.36,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,2.63,"[1.87-3.39] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[11,"rs147662640",6,28482917,"rs13191038","2018-07-19",29662059,"Howard DM","2018-04-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29662059","Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.","Depression (broad)","113,769 British ancestry cases, 208,811 British ancestry controls","NA","6p22.1","NR","GPX6, GPX6",null,null,"ENSG00000281185, ENSG00000198704",null,null,"rs13191038-C","rs13191038",0,13191038,"intron_variant",0,0.1101,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0131,"[0.0094-0.0168] unit decrease","NR [7666894] (imputed)","N"]
[16,"rs62466318",7,73056750,"rs6957745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Monocyte percentage of white cells","170,494 European ancestry individuals","NA","7q11.23","intergenic","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,17877,25405,"rs6957745-C","rs6957745",0,6957745,"intergenic_variant",1,0.2032,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0308444,"[0.022-0.04] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.803,{"v":4e-12,"d":"4.00E-12"},11.397940008672,"(East Asian)",0.126,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121420807,"rs1183910","2014-01-10",23844046,"Dorajoo R","2013-07-02","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23844046","Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?","C-reactive protein","2,179 Chinese ancestry individuals, 2,275 Malay ancestry individuals, 2,238 Asian Indian ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-G","rs1183910",0,1183910,"intron_variant",0,0.709,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.054,"[NR] unit increase","Illumina [up to 1745429] (imputed)","N"]
[32,"rs16940904",17,44192923,"rs17577369","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling miserable","376,097 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs17577369-A","rs17577369",0,17577369,"intron_variant",0,0.2157,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,6.96,"z score decrease","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2013-06-06",23419831,"Ramanan VK","2013-02-19","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/23419831","APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.","Alzheimer's disease biomarkers","555 European ancestry individuals","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-A","rs56131196",0,56131196,"intergenic_variant",1,0.29,{"v":4e-12,"d":"4.00E-12"},11.397940008672,"(Cortical Ab)",null,null,"Illumina [6108668] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2008-06-16",18193046,"Kooner JS","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193046","Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.","Triglycerides","1,005 European ancestry male individuals, 1,006 Indian Asian ancestry male individuals","6,827 European ancestry individuals, 2,528 Mexican ancestry individuals, 1,181 Indian Asian ancestry female individuals","8p21.3","SLC18A1, LPL, C8orf35","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.78,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,6.6,"[3.66-9.54] % increase","Perlegen [up to 216774]","N"]
[26,"rs10047462",11,116762028,"rs12285074","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","11q23.3",null,"SIK3",null,null,"ENSG00000160584",null,null,"rs12285074-A","rs12285074",0,12285074,"intron_variant",0,0.1012,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,0.0161,"[0.012-0.021] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[32,"rs16940904",17,43844560,"rs55657917","2018-08-16",29899525,"Klimentidis YC","2018-06-13","Int J Obes (Lond)","www.ncbi.nlm.nih.gov/pubmed/29899525","Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE.","Accelerometer-based physical activity measurement (average acceleration)","91,084 European ancestry individuals","NA","17q21.31","CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs55657917-T","rs55657917",0,55657917,"intron_variant",0,0.78,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,0.3,"milli-gravities decrease","Affymetrix [11800000] (imputed)","N"]
[32,"rs16940904",17,44354549,"rs2261201","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2261201-C","rs2261201",0,2261201,"intron_variant",0,0.214631,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,6.91,"z score decrease","NR [~ 10847151] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.0755,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,1.07,"[1.05-1.10]","Affymetrix, Illumina [247470]","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.89,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,"(BMI unadjusted)",0.109,"[0.078-0.14] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[16,"rs111432585",7,73056805,"rs62466330","2018-01-15",27680694,"Horikoshi M","2016-10-13","Nature","www.ncbi.nlm.nih.gov/pubmed/27680694","Genome-wide associations for birth weight and correlations with adult disease.","Birth weight","133,903 European ancestry individuals, 6,635 African American individuals, 420 Turkish ancestry individuals, 365 Moroccan ancestry individuals, 395 Surinamese ancestry individuals, 840 Chinese ancestry individuals.","9,799 European ancestry individuals, 1,449 Filipino ancestry individuals.","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,17932,25350,"rs62466330-C","rs62466330",0,62466330,"intergenic_variant",1,0.066,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,null,0.0512,"[0.037-0.066] unit increase","Affymetrix, Illumina [at least 22434434] (imputed)","N"]
[23,"rs4418728",10,94839642,"rs2068888","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-G","rs2068888",0,2068888,"regulatory_region_variant",1,0.536,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(EA)",0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs55891451",10,96707202,"rs4086116","2008-06-26",18535201,"Cooper GM","2008-06-05","Blood","www.ncbi.nlm.nih.gov/pubmed/18535201","A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.","Warfarin maintenance dose","181 European ancestry individuals","374 European ancestry individuals","10q23.33","CYP2C9","CYP2C9",null,null,"ENSG00000138109",null,null,"rs4086116-?","rs4086116",0,4086116,"intron_variant",0,"NR",{"v":6e-12,"d":"6.00E-12"},11.2218487496163,{"$nulls":3},"Illumina [538629]","N"]
[35,"rs11882123",19,19545696,"rs2965183","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","19p13.11","GATAD2A, MIR640","GATAD2A",null,null,"ENSG00000167491",null,null,"rs2965183-A","rs2965183",0,2965183,"intron_variant",0,0.35,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(EA)",1.04,"[1.02-1.06] (Oncoarray)","Illumina [~ 11800000] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2018-11-19",30220432,"Haas ME","2018-09-06","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30220432","Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.","Urinary albumin excretion","382,500 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-T","rs4665972",0,4665972,"intron_variant",0,0.393,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,0.01176,"[0.0084-0.0151] unit increase","Affymetrix [11709857] (imputed)","N"]
[17,"rs9987289",8,9185146,"rs2126259","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-A","rs2126259",0,2126259,"intron_variant",0,0.13,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,0.02,"[0.01-0.03] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[19,"rs2954021",8,126479315,"rs6982636","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982636-?","rs6982636",0,6982636,"intron_variant",0,"NR",{"v":7e-12,"d":"7.00E-12"},11.1549019599857,"(APOB.assay, whole)",1.95,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs11882123",19,19484295,"rs2905432","2018-12-17",29483656,"Pardinas AF","2018-02-26","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29483656","Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.","Schizophrenia","40,675 European ancestry cases, 64,643 European ancestry controls","1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls","19p13.11","CILP2, GATAD2A, HAPLN4, MAU2, NCAN, NDUFA13, PBX4, SUGP1, TM6SF2, TSSK6, YJEFN3","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,14731,12340,"rs2905432-?","rs2905432",0,2905432,"intergenic_variant",1,"NR",{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,1.071,"[1.05-1.09]","Illumina [8000000] (imputed)","N"]
[38,"rs4818005",21,40516070,"rs2836921","2018-09-12",29942086,"Savage JE","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942086","Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.","Intelligence","269,867 European ancestry individuals","NA","21q22.2","NR","RPL23AP12 - PCBP2P1","ENSG00000228861","ENSG00000235701",null,16104,26986,"rs2836921-A","rs2836921",0,2836921,"intergenic_variant",1,"NR",{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,6.867,"z-score increase","Affymetrix, Illumina [9295118] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.597,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(Hispanic)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65027610,"rs10761731","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,0.44,{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,0.031,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[27,"rs7970695",12,121438844,"rs735396","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.39,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(DG7)",0.1848085,"[0.13-0.24] (zscore) decrease","Illumina [NR]","N"]
[32,"rs16940904",17,43844560,"rs55657917","2019-01-18",30531941,"Doherty A","2018-12-10","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30531941","GWAS identifies 14 loci for device-measured physical activity and sleep duration.","Physical activity (overall physical activity time)","91,105 European ancestry individuals","NA","17q21.31","LINC02210-CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs55657917-T","rs55657917",0,55657917,"intron_variant",0,0.779584,{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,0.036815435,"[0.026-0.047] SD units decrease","NR [9926106] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(Epididymis-specific alpha-mannosidase, MAN2B2.9251.28.3)",0.23,"[0.17-0.29] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs10184054",2,21208211,"rs7557067","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,123678,13974,"rs7557067-G","rs7557067",0,7557067,"intergenic_variant",1,0.22,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,0.08,"[0.04-0.12] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[9,"rs10075801",5,131804347,"rs2248116","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Itch intensity from mosquito bite adjusted by bite size","41,355 European ancestry men and 43,369 European ancestry women","NA","5q31.1","C5orf56","C5orf56, AC116366.3",null,null,"ENSG00000197536, ENSG00000283782",null,null,"rs2248116-C","rs2248116",0,2248116,"intron_variant",0,"NR",{"v":9e-12,"d":"9.00E-12"},11.0457574905606,"(women)",0.031564,"[0.023-0.041] unit increase","Illumina [13520550] (imputed)","N"]
[22,"rs538711822",10,64927823,"rs1935","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs1935-?","rs1935",0,1935,"missense_variant",0,null,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,1.07,"[1.05-1.09]","Affymetrix, Illumina [43000000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index (age>50)","up to 90,988 European ancestry men, up to 106,622 European ancestry women","NA","19q13.32","APOC1, ZNF229, IGSF23, BCL3, PVRL2, CLPTM1, GEMIN7, EXOC3L2, KLC3, ZNF180, PVR, CBLC, TOMM40, RELB, PPP1R37, MARK4, ERCC1, CEACAM20, MIR4531, BCAM, APOE, CLASRP, BLOC1S3, CKM, CEACAM22P","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.82,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,0.04,"unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs200800380",5,131677997,"rs272869","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.37,{"v":1e-11,"d":"1.00E-11"},11,"(hexanoylcarnitine)",0.022,"[0.016-0.028] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[10,"rs6882345",5,156398169,"rs1501908","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,0.37,{"v":1e-11,"d":"1.00E-11"},11,null,0.07,"[0.03-0.11] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[11,"rs147662640",6,28630691,"rs13194504","2018-07-19",29662059,"Howard DM","2018-04-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29662059","Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.","Depression (broad)","113,769 British ancestry cases, 208,811 British ancestry controls","NA","6p22.1","NR","LINC00533 - RPSAP2","ENSG00000249032","ENSG00000249814",null,13848,69103,"rs13194504-A","rs13194504",0,13194504,"intergenic_variant",1,0.1122,{"v":1e-11,"d":"1.00E-11"},11,null,0.0127,"[0.009-0.0164] unit decrease","NR [7666894] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.802,{"v":1e-11,"d":"1.00E-11"},11,"(East Asian)",0.123,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.41,{"v":1e-11,"d":"1.00E-11"},11,null,2.218,"[1.58-2.85] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-A","rs112875651",0,112875651,"intron_variant",0,0.3925,{"v":1e-11,"d":"1.00E-11"},11,null,0.02517532,"[0.018-0.032] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs12718462",11,116805064,"rs77204473","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil counts","172,275 European ancestry individuals","NA","11q23.3","SIK3","SIK3",null,null,"ENSG00000160584",null,null,"rs77204473-G","rs77204473",0,77204473,"intron_variant",0,0.0553,{"v":1e-11,"d":"1.00E-11"},11,null,0.0528139,"[0.038-0.068] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","19p13.11","SF4, CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.91,{"v":1e-11,"d":"1.00E-11"},11,null,0.05,"[0.04-0.06] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[36,"rs429358",19,45424351,"rs814573","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,1745,5710,"rs814573-T","rs814573",0,814573,"intergenic_variant",1,0.198,{"v":1e-11,"d":"1.00E-11"},11,"(C-reactive protein, CRP.4337.49.2)",0.21,"[0.15-0.27] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs5112",19,45430280,"rs5112","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1P1","APOC1P1",null,null,"ENSG00000214855",null,null,"rs5112-G","rs5112",0,5112,"non_coding_transcript_exon_variant",0,0.535,{"v":1e-11,"d":"1.00E-11"},11,"(Neuronal pentraxin-2, NPTX2.6521.35.3)",0.18,"[0.12-0.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[3,"rs1167998",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(TG.by.NMR, fasting)",0.035,"[NR] unit decrease","Illumina [335603]","N"]
[4,"rs629301",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA, Catalase)",0.3359,"[0.24-0.43] unit decrease","Affymetrix [509946]","N"]
[10,"rs6882345",5,156479323,"rs1553318","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-C","rs1553318",0,1553318,"intron_variant",0,0.65,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.042,"[0.03-0.054] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[11,"rs147662640",6,28954293,"rs3129791","2018-07-19",29662059,"Howard DM","2018-04-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29662059","Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.","Depression (broad)","113,769 British ancestry cases, 208,811 British ancestry controls","NA","6p22.1","NR","HCG15, HCG15, HCG15, HCG15, HCG15",null,null,"ENSG00000225368, ENSG00000227214, ENSG00000237898, ENSG00000227380, ENSG00000233035",null,null,"rs3129791-A","rs3129791",0,3129791,"intron_variant",0,0.1148,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.0125,"[0.0088-0.0162] unit decrease","NR [7666894] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.529,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(Hispanic)",0.092,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.598,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(Hispanic)",0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.12,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.03,"[0.02-0.04] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-08-18",28548082,"Southam L","2017-05-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28548082","Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.","Triglyceride levels","up to 1,476 Mylopotamos (founder/genetic isolate) individuals, up to 1,737 Pomak (founder/genetic isolate) individuals","NA","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.163,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.236,"[0.17-0.30] unit increase","Illumina [at least 13541454] (imputed)","N"]
[29,"rs1561458",15,44245931,"rs2929282","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","15q15.3","FRMD5","FRMD5",null,null,"ENSG00000171877",null,null,"rs2929282-T","rs2929282",0,2929282,"intron_variant",0,0.05,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,5.13,"[3.44-6.82] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs1077835",15,58723939,"rs2070895","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA)",1.1494253,null,"Illumina [12023830] (imputed)","N"]
[32,"rs16940904",17,43696159,"rs675600","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","17q21.31","CRHR1-IT1, CRHR1, RP11-105N13.4","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,9875,1535,"rs675600-T","rs675600",0,675600,"intergenic_variant",1,0.2046,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.03056096,"[0.022-0.04] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,44826056,"rs9896243","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs9896243-G","rs9896243",0,9896243,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.01934,"[0.014-0.025] unit increase","Affymetrix [10847151] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(APOA1.assay, fasting)",2.616,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs58542926",19,19407718,"rs10401969","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-?","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid p-tau levels in mild cognitive impairment","581 European ancestry mild cognitive impairment cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.53,"[0.37-0.69] unit increase","Illumina [8446615] (imputed)","N"]
[9,"rs200800380",5,131660431,"rs273914","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs273914-A","rs273914",0,273914,"intron_variant",0,0.37,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(oleoylcarnitine)",0.023,"[0.015-0.031] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[11,"rs147662640",6,29133642,"rs141600123","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Squamous cell lung carcinoma","7,426 European ancestry cases, 55,627 European ancestry controls","NA","6p22.1","OR2J3, OR2J2","AL645937.4",null,null,"ENSG00000284656",null,null,"rs141600123-T","rs141600123",1,4947263,"non_coding_transcript_exon_variant",0,0.098184885,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,1.24441,"[1.1670044-1.326950001]","Illumina [10439017] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2013-08-21",23388002,"Thanassoulis G","2013-02-17","N Engl J Med","www.ncbi.nlm.nih.gov/pubmed/23388002","Genetic associations with valvular calcification and aortic stenosis.","Aortic-valve calcification","6,942 European ancestry individuals","745 European ancestry individuals, 2,497 African American individuals, 2,027 Hispanic individuals, 774 Chinese ancestry individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.07,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(EA)",2.05,"[1.66-2.53]","Affymetrix, Illumina [> 2500000] (imputed)","N"]
[18,"rs76722925",8,19832646,"rs17482753","2010-01-13",20031538,"Heid IM","2008-10-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031538","Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.","HDL cholesterol","Up to 4,274 European ancestry individuals","Up to 15,873 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-T","rs17482753",0,17482753,"regulatory_region_variant",1,0.11,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,2.02,"[NR] mg/dl increase","Affymetrix [up to 2557253] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.875,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(East Asian)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2018-11-19",30220432,"Haas ME","2018-09-06","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30220432","Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.","Urinary albumin excretion","382,500 European ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.579,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.01136,"[0.008-0.0147] unit increase","Affymetrix [11709857] (imputed)","N"]
[22,"rs538711822",10,65165184,"rs10822168","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total bilirubin levels","110,207 Japanese ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10822168-?","rs10822168",0,10822168,"intron_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.02888,"[0.02-0.037] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2266788",11,116652423,"rs6589566","2008-06-16",18179892,"Wallace C","2008-01-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18179892","Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.","LDL cholesterol","1,955 European ancestry hypertensive individuals","2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins","11q23.3","APOA1, APOC3, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs6589566-G","rs6589566",0,6589566,"intron_variant",0,0.06,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,{"$nulls":3},"Affymetrix [400496]","N"]
[26,"rs2266788",11,116662579,"rs651821","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Mean corpuscular hemoglobin concentration","108,728 Japanese ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-?","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.02925,"[0.021-0.038] unit decrease novel","Illumina [6108953] (imputed)","N"]
[27,"rs7970695",12,121403724,"rs7953249","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.47,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(DG9)",0.17475872,"[0.12-0.23] (zscore) decrease","Illumina [NR]","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43564222,"rs144733372","2018-07-10",29559929,"Amare AT","2018-03-06","Front Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29559929","Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.","Remission after SSRI treatment in MDD or neuroticism","865 individuals with SSRI response data, 170,911 individuals with personality trait data","NA","17q21.31","PLEKHM1","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs144733372-G","rs144733372",1,9899111,"intron_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,{"$nulls":3},"NR [NR] (imputed)","N"]
[32,"rs16940904",17,44351387,"rs2732708","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling miserable","376,097 European ancestry individuals","NA","17q21.31","NR","AC005829.1 - ARL17B","ENSG00000261575","ENSG00000228696",null,5327,763,"rs2732708-T","rs2732708",0,2732708,"intergenic_variant",1,0.214039,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,6.64,"z score increase","NR [10847151] (imputed)","N"]
[32,"rs16940904",17,44860021,"rs70600","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","17q21.31","NR","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs70600-T","rs70600",0,70600,"intron_variant",0,0.20718,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,6.65,"z score increase","NR [~ 10847151] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cognitive impairment test score","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,2.768712,"[NR] unit decrease","Illumina [575353]","N"]
[7,"rs11681659",2,136707982,"rs6754311","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","2q21.3","DARS","DARS",null,null,"ENSG00000115866",null,null,"rs6754311-T","rs6754311",0,6754311,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.0390103,"[0.027-0.051] unit increase","Illumina [13520550] (imputed)","N"]
[11,"rs147662640",6,28250179,"rs34878803","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Squamous cell lung carcinoma","7,426 European ancestry cases, 55,627 European ancestry controls","NA","6p22.1","PGBD1","PGBD1",null,null,"ENSG00000137338",null,null,"rs34878803-C","rs34878803",0,34878803,"intron_variant",0,0.077210179,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,1.2508706,"[1.170617536-1.336625496]","Illumina [10439017] (imputed)","N"]
[11,"rs147662640",6,28803291,"rs9257248","2018-07-19",29662059,"Howard DM","2018-04-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29662059","Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.","Depression (broad)","113,769 British ancestry cases, 208,811 British ancestry controls","NA","6p22.1","NR","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,51510,2355,"rs9257248-T","rs9257248",0,9257248,"intergenic_variant",1,0.114,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.0123,"[0.0086-0.016] unit decrease","NR [7666894] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73042443,"rs6460047","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3570,39712,"rs6460047-C","rs6460047",0,6460047,"intergenic_variant",1,0.208,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.0108214,"[0.0076-0.014] unit increase","NR [~ 9732723] (imputed)","N"]
[16,"rs62466318",7,73056750,"rs6957745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte percentage of myeloid white cells","169,545 European ancestry individuals","NA","7q11.23","intergenic","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,17877,25405,"rs6957745-C","rs6957745",0,6957745,"intergenic_variant",1,0.2032,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.02946504,"[0.021-0.038] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,65104500,"rs7896518","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability (MTAG)","436,124 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-?","rs7896518",0,7896518,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,6.619,"z score decrease","Affymetrix, Illumina, Perlegen [7333576] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean platelet volume","164,454 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8668,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.03519076,"[0.025-0.046] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Platelet count","108,208 Japanese ancestry individuals","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.02899,"[0.02-0.038] unit increase novel","Illumina [6108953] (imputed)","N"]
[26,"rs139857231",11,117023487,"rs7128382","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Systolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","11q23.3","PAFAH1B2","PAFAH1B2",null,null,"ENSG00000168092",null,null,"rs7128382-A","rs7128382",0,7128382,"intron_variant",0,0.2123,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.2688,"[0.19-0.35] mmHg increase","Affymetrix [NR] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.334,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(AA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2012-10-19",21102463,"Franke A","2010-11-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21102463","Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.","Crohn's disease","6,333 European ancestry cases, 15,056 European ancestry controls","15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.418,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,1.15,"[1.10-1.21]","Affymetrix, Illumina [953241] (imputed)","N"]
[22,"rs538711822",10,65336185,"rs7077256","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs7077256-A","rs7077256",0,7077256,"intron_variant",0,"NR",{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.019172957,"[0.013-0.025] unit increase","Affymetrix [NR]","N"]
[23,"rs4418728",10,94839642,"rs2068888","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-G","rs2068888",0,2068888,"regulatory_region_variant",1,0.536,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(EA)",0.026,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43977827,"rs1864325","2013-04-11",22504420,"Estrada K","2012-04-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22504420","Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.","Lumbar spine bone mineral density","Up to 32,961 European and East Asian ancestry individuals","Up to 50,933 European and East Asian ancestry individuals","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs1864325-T","rs1864325",0,1864325,"intron_variant",0,0.22,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.04,"[NR] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.825,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(AA)",0.215,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.336,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(AA)",0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2014-03-01",23903356,"Hayes MG","2013-07-31","Diabetes","www.ncbi.nlm.nih.gov/pubmed/23903356","Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.","Glycemic traits (pregnancy)","1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean individuals, 1,178 Thai ancestry individuals","2,798 European ancestry individuals, 228 French Canadian founder population individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.409,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(FCP)",0.0116,"[NR] unit decrease","Illumina [up to 945994] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.231,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(Hispanic)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,0.945,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(EA)",0.072,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.833,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(AA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-04-21",27899376,"Nakayama A","2016-11-29","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/27899376","GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.","Gout","945 Japanese ancestry cases, 1,213 Japanese ancestry controls","1,396 Japanese ancestry cases, 1,268 Japanese ancestry controls, 1,319 European ancestry cases, 514 European ancestry controls, 971 Polynesian ancestry cases, 565 Polynesian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.535,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(Japanese)",1.31,"[1.21-1.42]","Illumina [570442]","N"]
[11,"rs147662640",6,28358009,"rs13213986","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Squamous cell lung carcinoma","7,426 European ancestry cases, 55,627 European ancestry controls","NA","6p22.1","ZSCAN12","ZSCAN12",null,null,"ENSG00000158691",null,null,"rs13213986-A","rs13213986",0,13213986,"intron_variant",0,0.076648757,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,1.2491379,"[1.168376851-1.335481193]","Illumina [10439017] (imputed)","N"]
[18,"rs34669405",8,19928160,"rs10106652","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103390,8465,"rs10106652-A","rs10106652",0,10106652,"intergenic_variant",1,0.273,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,0.048,"[0.034-0.062] unit decrease","Affymetrix [7947838] (imputed)","N"]
[30,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2013-03-19",23222517,"van der Harst P","2012-12-05","Nature","www.ncbi.nlm.nih.gov/pubmed/23222517","Seventy-five genetic loci influencing the human red blood cell.","Red blood cell traits","62,553 European ancestry individuals, 9,308 South Asian ancestry individuals","63,506 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(Hgb)",0.034,"[0.022-0.046] unit increase","Affymetrix, Illumina, Perlegen [2711806] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.166036,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,1.1,"[1.07- 1.13]","Affymetrix, Illumina [8600000] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2015-04-24",21239051,"Reilly MP","2011-01-14","Lancet","www.ncbi.nlm.nih.gov/pubmed/21239051","Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.","Coronary artery disease","1,808 European ancestry cases, 915 European ancestry controls","10,585 European ancestry cases, 6,468 European ancestry controls","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.79,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,1.33,"[1.22-1.44]","Affymetrix, Illumina [> 2400000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3198697",16,15129940,"rs3198697","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-C","rs3198697",0,3198697,"missense_variant",0,0.585,{"v":8e-11,"d":"8.00E-11"},10.096910013008,"(EA)",0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.989,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,"(Hispanic)",0.464,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,"(Women)",0.041,"[0.029-0.053] nmol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[26,"rs11216127",11,116617240,"rs11216126","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","Intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,88272,1646,"rs11216126-?","rs11216126",0,11216126,"intergenic_variant",1,null,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal AB1-42 levels in normal cognition","305 European ancestry cognitively normal individuals","NA","19q13.32","APOE, BCAM, PVRLTOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,null,0.84,"[0.59-1.09] unit decrease","Illumina [8257341] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-07-04",29769521,"Ramirez J","2018-05-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29769521","Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.","Resting heart rate","67,062 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.397939,{"v":1E-10,"d":"1.00E-10"},10,null,0.422407,"[0.29-0.55] unit increase","Affymetrix [~ 7800000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2014-03-27",24068962,"O'Seaghdha CM","2013-09-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/24068962","Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.","Calcium levels","39,400 European ancestry individuals","Up to 21,679 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.42,{"v":1E-10,"d":"1.00E-10"},10,null,0.017,"[0.016-0.018] unit increase","Affymetrix, Illumina [2500000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73042443,"rs6460047","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3570,39712,"rs6460047-C","rs6460047",0,6460047,"intergenic_variant",1,0.208,{"v":1E-10,"d":"1.00E-10"},10,null,0.011623538,"[0.0081-0.0151] unit increase","NR [~ 10000000] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.803,{"v":1E-10,"d":"1.00E-10"},10,"(East Asian)",0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,0.758,{"v":1E-10,"d":"1.00E-10"},10,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs4360309",8,126523523,"rs4360309","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Basophil percentage of white cells","171,996 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-T","rs4360309",0,4360309,"intron_variant",0,0.4888,{"v":1E-10,"d":"1.00E-10"},10,null,0.02297412,"[0.016-0.03] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121420260,"rs7979473","2012-11-02",22939635,"Reiner AP","2012-08-28","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/22939635","Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.","C-reactive protein","8,280 African American female individuals, 3,548 Hispanic female individuals","3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7979473-A","rs7979473",0,7979473,"intron_variant",0,0.443,{"v":1E-10,"d":"1.00E-10"},10,"(AA women)",0.119,"[0.082-0.156] unit decrease","Affymetrix [up to 2203609] (imputed)","N"]
[32,"rs112557952",17,43902541,"rs4327090","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Highest math class taken","430,445 European ancestry individuals","NA","17q21.31","Intergenic","CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1, LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000278232, ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000263715, ENSG00000282456",null,null,"rs4327090-A","rs4327090",0,4327090,"intron_variant",0,0.8074,{"v":1E-10,"d":"1.00E-10"},10,null,0.0186,"[0.013-0.024] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[32,"rs2732699",17,44354904,"rs2732699","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2732699-C","rs2732699",0,2732699,"intron_variant",0,0.8401,{"v":1E-10,"d":"1.00E-10"},10,"(EA)",0.0595,"[0.041-0.078] unit increase","Illumina [~ 11800000] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2013-06-06",23419831,"Ramanan VK","2013-02-19","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/23419831","APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.","Alzheimer's disease biomarkers","555 European ancestry individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.28,{"v":1E-10,"d":"1.00E-10"},10,"(Cortical Ab)",null,null,"Illumina [6108668] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-08-22",29860282,"Scelsi MA","2018-05-30","Brain","www.ncbi.nlm.nih.gov/pubmed/29860282","Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.","Hippocampal volume","926 European ancestry individuals","NA","19q13.32","APOE4","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,null,{"v":1E-10,"d":"1.00E-10"},10,"(uncorrected for APOE4 status)",null,null,"Illumina [5137218] (imputed)","N"]
[3,"rs1167998",1,63107526,"rs995000","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.18,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(BMI unadjusted)",0.085,"[0.06-0.11] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[4,"rs629301",1,109817838,"rs660240","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.21541,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.014155,"[0.0098-0.0185] unit increase","NR [13737936] (imputed)","N"]
[7,"rs11681659",2,136381348,"rs12465802","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","2q21.3","R3HDM1","R3HDM1",null,null,"ENSG00000048991",null,null,"rs12465802-G","rs12465802",0,12465802,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0368262,"[0.026-0.048] unit increase","Illumina [13520550] (imputed)","N"]
[8,"rs9884390",4,69349018,"rs1117816","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4q13.2","TMPRSS11E","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs1117816-A","rs1117816",0,1117816,"intron_variant",0,0.78,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0212,"[0.015-0.028] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[11,"rs147662640",6,28482917,"rs114242735","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Squamous cell lung carcinoma","7,426 European ancestry cases, 55,627 European ancestry controls","NA","6p22.1","GPX6","GPX6, GPX6",null,null,"ENSG00000281185, ENSG00000198704",null,null,"rs114242735-C","rs114242735",1,13191038,"intron_variant",0,0.076962679,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.241532,"[1.161109238-1.327525094]","Illumina [10439017] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73020337,"rs3812316","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs3812316-C","rs3812316",0,3812316,"missense_variant",0,0.8812,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0213,"[0.015-0.028] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[17,"rs9987289",8,9183596,"rs4841132","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin (BMI interaction)","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0937,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.001989,"[0.0001-0.00388] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[17,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.804,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(East Asian)",0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte count","169,822 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-T","rs2954031",0,2954031,"intron_variant",0,0.4452,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.02300901,"[0.016-0.03] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs5128",11,116702362,"rs645901","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","11q23.3","APOC3","APOC3",null,null,"ENSG00000110245",null,null,"rs645901-C","rs645901",0,645901,"intron_variant",0,0.8657,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.03454995,"[0.024-0.045] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs12718462",11,116706047,"rs12721025","2014-03-21",23989729,"Feenstra B","2013-08-21","JAMA","www.ncbi.nlm.nih.gov/pubmed/23989729","Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.","Infantile hypertrophic pyloric stenosis","1,001 European ancestry cases, 2,371 European ancestry controls","925 European ancestry cases, 1,621 European ancestry controls, 738 cases, 697 controls","11q23.3","APOA1","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,2259,420,"rs12721025-A","rs12721025",0,12721025,"regulatory_region_variant",1,0.0569,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.59,"[1.38-1.83]","Illumina [9737928] (imputed)","N"]
[27,"rs7970695",12,121442670,"rs1169313","2008-12-01",18940312,"Yuan X","2008-10-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18940312","Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.","Liver enzyme levels","7,751 European ancestry individuals","1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals","12q24.31","C12orf43, C12orf27, HNF1A","C12orf43",null,null,"ENSG00000157895",null,null,"rs1169313-C","rs1169313",0,1169313,"intron_variant",0,0.38,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(GGT)",0.01,"[0.003-0.007] U/L decrease","Affymetrix, Illumina [up to 496032]","N"]
[28,"rs6602911",13,114551993,"rs6602909","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","13q34","GAS6","GAS6",null,null,"ENSG00000183087",null,null,"rs6602909-C","rs6602909",0,6602909,"intron_variant",0,0.3251,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.02435825,"[0.017-0.032] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","HDL cholesterol","4,763 Northern Finnish founder individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.44,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.05,"[0.03-0.06] mmol/l increase","Illumina [329091]","N"]
[30,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.028,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15130351,"rs1741","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","8,631 European ancestry individuals","NA","16p13.11","PDXDC1, NTAN1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs1741-C","rs1741",0,1741,"3_prime_UTR_variant",0,0.308,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.2,"[NR] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs35076622",17,43851498,"rs35909029","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs35909029-T","rs35909029",0,35909029,"intron_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,6.385,"z score increase","Affymetrix [10847151] (imputed)","N"]
[35,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.051,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19379549,"rs58542926","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.079,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.09,"[1.06-1.12]","Affymetrix, Illumina [247470]","N"]
[2,"rs11591147",1,55505647,"rs11591147","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.984,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,1.25,"[1.16-1.34]","Affymetrix [9149595] (imputed)","N"]
[3,"rs1167998",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(VLDL.medium, fasting)",1.32,"[NR] unit decrease","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2010-02-08",20081857,"Saxena R","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081857","Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.","Two-hour glucose challenge","15,234 individuals","up to 30,620 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.07,"[0.05-0.09] mmol/L increase","Affymetrix, Illumina [NR]","N"]
[6,"rs1260326",2,27748904,"rs1313566","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Prothrombin time","58,110 Japanese ancestry individuals","NA","2p23.3","GCKR, C2orf16","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2353,11349,"rs1313566-?","rs1313566",0,1313566,"intergenic_variant",1,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.03744,"[0.026-0.049] unit increase novel","Illumina [6108953] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.09,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(TG)",0.071,"[0.026-0.116] mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[19,"rs112875651",8,126500031,"rs28601761","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.42,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.00849258,"[0.0059-0.0111] unit increase","NR [~ 9732723] (imputed)","N"]
[26,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121435587,"rs2259816","2012-11-02",22939635,"Reiner AP","2012-08-28","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/22939635","Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.","C-reactive protein","8,280 African American female individuals, 3,548 Hispanic female individuals","3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals","12q24.31","OASL, C12orf43, HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs2259816-T","rs2259816",0,2259816,"synonymous_variant",0,0.379,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(HA women)",0.141,"[0.092-0.190] unit increase","Affymetrix [up to 2203609] (imputed)","N"]
[32,"rs16940904",17,43682323,"rs186806998","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FEV1)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","LOC644172, CRHR1","MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,2617,3614,"rs186806998-T","rs186806998",1,56383763,"intergenic_variant",1,0.82,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,29.5,"[20.29-38.71] ml increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[34,"rs142158911",19,11193949,"rs10412048","2019-04-02",30166351,"Galvan-Femenia I","2018-08-30","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/30166351","Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.","Disorders of lipid metabolism","4,988 Spanish ancestry individuals","NA","19p13.2","SMARCA4, LDLR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,3847,6089,"rs10412048-?","rs10412048",0,10412048,"intergenic_variant",1,null,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(Disorders of lipid metabolism)",0.50094855,"[0.34-0.66] unit decrease","Illumina [9499600] (imputed)","N"]
[3,"rs1167998",1,62993403,"rs61775910","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs61775910-?","rs61775910",0,61775910,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.03518,"[0.024-0.046] unit decrease novel","Illumina [6108953] (imputed)","N"]
[3,"rs1167998",1,63085997,"rs12239736","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12239736-A","rs12239736",0,12239736,"intron_variant",0,0.352174,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.07167609,"[0.049-0.094] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","Metabolic traits","4,763 Northern Finnish founder individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-A","rs1260326",0,1260326,"missense_variant",0,0.35,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(TG)",0.09,"[0.06-0.12] mmol/l increase","Illumina [329091]","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-11-25",26833098,"Kilpelainen TO","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833098","Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.","circulating leptin levels adjusted for BMI","up to 14,094 European ancestry men, up to 19,893 European ancestry women","up to 9,076 European ancestry men, up to 9,150 European ancestry women","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,0.61,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.024,"[0.016-0.032] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[18,"rs15285",8,19870271,"rs35237252","2017-08-17",28548082,"Southam L","2017-05-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28548082","Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.","High density lipoprotein cholesterol levels","up to 1,476 Mylopotamos (founder/genetic isolate) individuals, up to 1,737 Pomak (founder/genetic isolate) individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,45501,66354,"rs35237252-A","rs35237252",0,35237252,"regulatory_region_variant",1,0.277,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.183,"[0.13-0.24] unit increase","Illumina [at least 13541454] (imputed)","N"]
[19,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.029,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs10899133",11,75531695,"rs10899133","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","11q13.5","UVRAG","UVRAG",null,null,"ENSG00000198382",null,null,"rs10899133-T","rs10899133",0,10899133,"intron_variant",0,0.1063,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.03597418,"[0.025-0.047] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs139974673",15,44027885,"rs139974673","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Monocyte percentage of white cells","170,494 European ancestry individuals","NA","15q15.3","CATSPER2P1","CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs139974673-C","rs139974673",0,139974673,"intron_variant",0,0.026,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.07087201,"[0.049-0.093] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs11882123",19,19478022,"rs2905426","2015-04-16",25056061,"Ripke S","2014-07-22","Nature","www.ncbi.nlm.nih.gov/pubmed/25056061","Biological insights from 108 schizophrenia-associated genetic loci.","Schizophrenia","32,405 European ancestry cases, 42,221 European ancestry controls, 1,235 European ancestry cases and 1,235 European ancestry controls from 1235 parent-offspring trios, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls","1,513 European ancestry cases, 66,236 European ancestry controls","19p13.11","CILP2, GATAD2A, HAPLN4, MAU2, NCAN, NDUFA13, PBX4, SUGP1, TM6SF2, TSSK6","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,8458,18613,"rs2905426-G","rs2905426",0,2905426,"TF_binding_site_variant",1,0.372,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,1.0706638,"[1.05-1.09]","Affymetrix, Illumina [9005918] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA, Repulsive guidance molecule A)",0.3237,"[0.22-0.42] unit decrease","Affymetrix [509946]","N"]
[19,"rs2954021",8,126491733,"rs2954031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-T","rs2954031",0,2954031,"intron_variant",0,0.4453,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.02247202,"[0.015-0.03] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[27,"rs7970695",12,121403724,"rs7953249","2017-08-04",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Epithelial ovarian cancer","16,924 European ancestry cases, 68,502 European ancestry controls","NA","12q24.31","NR","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.417632,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,1.0834533,"[1.05604177574809-1.1115762691869]","Illumina [11595112] (imputed)","N"]
[28,"rs6602911",13,114551993,"rs6602909","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","13q34","FLJ41484","GAS6",null,null,"ENSG00000183087",null,null,"rs6602909-C","rs6602909",0,6602909,"intron_variant",0,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.0256522,"[0.017-0.034] unit increase","Affymetrix [16832071] (imputed)","N"]
[29,"rs139974673",15,44028047,"rs147233090","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","15q15.3","CATSPER2P1","CATSPER2P1",null,null,"ENSG00000205771",null,null,"rs147233090-T","rs147233090",0,147233090,"intron_variant",0,0.0241,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.073863,"[0.051-0.097] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,44227393,"rs2696579","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2696579-A","rs2696579",0,2696579,"intron_variant",0,0.3371,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.02511521,"[0.017-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs9304381",18,47159090,"rs7240405","2010-01-13",20031538,"Heid IM","2008-10-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031538","Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.","HDL cholesterol","Up to 4,274 European ancestry individuals","Up to 15,873 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,33538,17630,"rs7240405-A","rs7240405",0,7240405,"intergenic_variant",1,0.15,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,2.27,"[NR] mg/dl decrease","Affymetrix [up to 2557253] (imputed)","N"]
[9,"5:131664516_TTATATA_T",5,131722951,"rs274555","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","5q31.1","NR","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274555-?","rs274555",0,274555,"intron_variant",0,"NR",{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(male)",0.22148,"[0.15-0.29] unit decrease","Affymetrix [7794483] (imputed)","N"]
[13,"rs10455872",6,161005610,"rs55730499","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (mother's attained age)","412,937 British ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-C","rs55730499",0,55730499,"intron_variant",0,"NR",{"v":6E-10,"d":"6.00E-10"},9.22184874961635,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[22,"rs538711822",10,65027610,"rs10761731","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interleukin-12p70 levels","8,270 Finnish ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-T","rs10761731",0,10761731,"intron_variant",0,null,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.1001,"[0.068-0.132] SD units increase","NR [10700000] (imputed)","N"]
[32,"rs16940904",17,43810896,"rs77804065","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling guilty","373,380 European ancestry individuals","NA","17q21.31","ACBD4","LINC02210-CRHR1, LINC02210-CRHR1, AC217774.2",null,null,"ENSG00000263715, ENSG00000282456, ENSG00000265964",null,null,"rs77804065-T","rs77804065",0,77804065,"splice_region_variant",0,0.217158,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,6.18,"z score increase","NR [10847151] (imputed)","N"]
[9,"rs200800380",5,131677997,"rs272869","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference adjusted for body mass index","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4038,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(EA)",0.0212,"[0.015-0.028] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[11,"rs147662640",6,28304384,"rs67340775","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","ZSCAN31","ZSCAN31",null,null,"ENSG00000235109",null,null,"rs67340775-C","rs67340775",0,67340775,"intron_variant",0,0.079332947,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,1.1820452,"[1.120847747-1.246584078]","Illumina [10439017] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(EA)",0.044,"[0.03-0.058] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,65274927,"rs10761779","2008-12-01",18940312,"Yuan X","2008-10-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18940312","Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.","Liver enzyme levels","7,751 European ancestry individuals","1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals","10q21.3","REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761779-G","rs10761779",0,10761779,"intron_variant",0,0.49,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(ALP)",0.03,"[0.017-0.033] U/L increase","Affymetrix, Illumina [up to 496032]","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.409,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(Hispanic)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2016-12-08",26833246,"Lu Y","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833246","New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.","Body fat percentage","Up to 31,457 European ancestry men, up to 35,030 European ancestry women, up to 8,259 Indian Asian ancestry men, up to 1,030 Indian Asian ancestry women, 973 Korean ancestry men, 1,360 Korean ancestry women, 154 African American men, 262 African American women","Up to 12,480 European ancestry men, up to 10,055 European ancestry women, 315 Jamaican ancestry men, 774 Jamaican ancestry women","19q13.32","TOMM40, APOE","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-C","rs6857",0,6857,"3_prime_UTR_variant",0,0.83,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(European)",0.053,"[0.035-0.071] body fat % increase","Affymetrix, Illumina, Perlegen [at least 1958375] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.02209369,"[0.015-0.029] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27734972,"rs6547692","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Chloride levels","126,402 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs6547692-?","rs6547692",0,6547692,"intron_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.02467,"[0.017-0.033] unit increase","Illumina [6108953] (imputed)","N"]
[11,"rs147662640",6,29461730,"rs1233491","2016-01-30",25827949,"Kunz M","2015-05-04","Exp Dermatol","www.ncbi.nlm.nih.gov/pubmed/25827949","Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.","Cutaneous lupus erythematosus","151 European ancestry cases, 1,288 European ancestry controls","219 European ancestry cases, 262 European ancestry controls","6p22.1","MAS1L","RPS17P1 - AL662860.1","ENSG00000213900","ENSG00000229274",null,4277,3556,"rs1233491-C","rs1233491",0,1233491,"intergenic_variant",1,0.088,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,2.2,"[1.58-3.08]","Affymetrix [906600]","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.913,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,"(Hispanic)",0.15,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs6589563",11,116590787,"rs6589563","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil counts","172,275 European ancestry individuals","NA","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,61819,28099,"rs6589563-A","rs6589563",0,6589563,"intergenic_variant",1,0.0786,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.0410643,"[0.028-0.054] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs56224630",11,116603724,"rs12272004","2009-02-28",19185284,"Ferrucci L","2009-01-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/19185284","Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.","Carotenoid and tocopherol levels","1,191 European ancestry individuals","2,540 European ancestry individuals, 211 individuals","11q23.3","APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,74756,15162,"rs12272004-A","rs12272004",0,12272004,"TF_binding_site_variant",1,0.07,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,"(alpha-tocopherol)",0.07,"[0.049-0.095] umol/L increase","Illumina [~ 500451]","N"]
[30,"rs1077835",15,58723939,"rs2070895","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-G","rs2070895",0,2070895,"intron_variant",0,0.77,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.1424,"[0.097-0.188] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2016-09-20",26482880,"Buch S","2015-10-19","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26482880","A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis.","Cirrhosis (alcohol related)","712 European ancestry cases, 1,426 European ancestry alchocol dependent controls","1,148 European ancestry cases, 922 European ancestry alchocol dependent controls","19p13.11","TM6SF2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.08,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,1.72,"[1.44–2.04]","Illumina [6770425] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.88,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116586283,"rs7350481","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-T","rs7350481",0,7350481,"regulatory_region_variant",1,0.28,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(HDL)",0.124,"[0.085-0.163] unit decrease","Illumina [561583]","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.897,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(Hispanic)",0.152,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19702384,"rs17217098","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte percentage of white cells","171,748 European ancestry individuals","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs17217098-A","rs17217098",0,17217098,"intron_variant",0,0.0677,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,0.04375895,"[0.03-0.058] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[5,"rs668948",2,21288321,"rs562338","2008-09-15",18262040,"Sandhu MS","2008-02-09","Lancet","www.ncbi.nlm.nih.gov/pubmed/18262040","LDL-cholesterol concentrations: a genome-wide association study.","LDL cholesterol","11,685 European ancestry individuals","Up to 4,979 European ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-T","rs562338",0,562338,"intergenic_variant",1,0.2,{"v":1e-09,"d":"1.00E-09"},9,null,0.04,"[0.02-0.06] mmol/L decrease","Affymetrix, Illumina [up to 461986]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Isoleucine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-09,"d":"1.00E-09"},9,null,0.06,"[0.036-0.084] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[6,"rs3817588",2,27743154,"rs780092","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-A","rs780092",0,780092,"intron_variant",0,0.67,{"v":1e-09,"d":"1.00E-09"},9,"(Asian initial, BMI unadjusted)",0.053,"[0.035-0.071] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs77200710",2,27851918,"rs3749147","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","2p23.3","CCDC121","GPN1, AC074091.1",null,null,"ENSG00000198522, ENSG00000259080",null,null,"rs3749147-C","rs3749147",0,3749147,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.18,"[0.12-0.24] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[11,"rs147662640",6,28332141,"rs13214023","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","ZKSCAN3",null,null,"ENSG00000189298",null,null,"rs13214023-A","rs13214023",0,13214023,"intron_variant",0,0.0929,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",0.071,"[0.048-0.094] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2012-03-17",22368281,"Deshmukh HA","2012-02-24","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/22368281","Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).","Response to statin therapy","2,702 European ancestry individuals","2,550 European ancestry individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.28,"[0.20-0.36] mmol/L decrease","Illumina, Perlegen [NR] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.12,{"v":1e-09,"d":"1.00E-09"},9,null,0.57,"[0.33-0.81] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126479315,"rs6982636","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982636-?","rs6982636",0,6982636,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(TG.assay, whole)",0.033,"[NR] unit decrease","Illumina [335603]","N"]
[19,"rs33924196",8,126481475,"rs2980879","2012-05-10",22479202,"Dastani Z","2012-03-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22479202","Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.","Adiponectin levels","29,347 European ancestry individuals, 4,232 African American individuals, 1,776 Filipino ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980879-T","rs2980879",0,2980879,"intron_variant",0,0.69,{"v":1e-09,"d":"1.00E-09"},9,null,0.03,"[0.022-0.038] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[22,"rs538711822",10,65333648,"rs6479908","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs6479908-C","rs6479908",0,6479908,"intron_variant",0,null,{"v":1e-09,"d":"1.00E-09"},9,null,0.142,"unit decrease","Affymetrix [at least 2696785] (imputed)","N"]
[26,"rs1269325",11,116576415,"rs1263056","2019-04-12",30846698,"Dashti HS","2019-03-07","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30846698","Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.","Sleep duration","446,118 European ancestry individuals","47,180  adults, 10,554 children or adolescents","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,47447,42471,"rs1263056-A","rs1263056",0,1263056,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.768,"unit increase","Affymetrix [14661600] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.121,{"v":1e-09,"d":"1.00E-09"},9,"(Hispanic)",0.116,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs10047462",11,116908283,"rs7115242","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs7115242-?","rs7115242",0,7115242,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"Affymetrix [NR]","N"]
[29,"rs1561458",15,44218136,"rs481837","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs481837-C","rs481837",0,481837,"intron_variant",0,0.956,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",0.056,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs145326144",15,44564692,"rs144972973","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","15q15.3","intergenic","FRMD5 - CASC4","ENSG00000171877","ENSG00000166734",null,77242,16235,"rs144972973-G","rs144972973",0,144972973,"intergenic_variant",1,0.02588,{"v":1e-09,"d":"1.00E-09"},9,null,9.93,"[6.74-13.12] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[30,"rs261341",15,58724792,"rs8034802","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","HDL cholesterol","7,813 African American individuals","4,323 African American and Afro-Caribbean individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs8034802-A","rs8034802",0,8034802,"intron_variant",0,0.362,{"v":1e-09,"d":"1.00E-09"},9,null,0.104,"[0.071-0.137] unit increase","Affymetrix [~ 2740000] (imputed)","N"]
[31,"rs72789541",16,15129970,"rs7200543","2017-10-27",28892062,"Akiyama M","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892062","Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.","Body mass index","up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men","up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs7200543-G","rs7200543",0,7200543,"synonymous_variant",0,0.32,{"v":1e-09,"d":"1.00E-09"},9,null,0.015,"[0.011-0.019] kg/m2 decrease","Illumina [6108953] (imputed)","N"]
[32,"rs16940904",17,43903842,"rs62057151","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling worry","372,869 European ancestry individuals","NA","17q21.31","NR","CRHR1, LINC02210-CRHR1, LINC02210-CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs62057151-T","rs62057151",0,62057151,"non_coding_transcript_exon_variant",0,0.223812,{"v":1e-09,"d":"1.00E-09"},9,null,6.049,"unit increase","NR [10847151] (imputed)","N"]
[32,"rs16940904",17,43924200,"rs12373142","2019-05-01",30804561,"Sakornsakolpat P","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804561","Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.","Chronic obstructive pulmonary disease","35,735 cases, 222,076 controls","NA","17q21.31","SPPL2C","MAPT-AS1, MAPT-AS1, MAPT-AS1, SPPL2C, SPPL2C, SPPL2C",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067, ENSG00000277106, ENSG00000185294, ENSG00000278194",null,null,"rs12373142-G","rs12373142",0,12373142,"missense_variant",0,0.22,{"v":1e-09,"d":"1.00E-09"},9,null,1.08,"[1.05-1.10]","Affymetrix, Illumina [6224355] (imputed)","N"]
[32,"rs16940904",17,44847834,"rs199525","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FEV1)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199525-T","rs199525",0,199525,"intron_variant",0,0.8,{"v":1e-09,"d":"1.00E-09"},9,null,18.85,"[12.81-24.89] ml increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[33,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(HDL-C.assay, whole)",1.238,"[NR] unit decrease","Illumina [335603]","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.9,{"v":1e-09,"d":"1.00E-09"},9,"(Hispanic)",0.153,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs61061000",19,19263938,"rs58190593","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Mean arterial pressure","136,482 Japanese ancestry individuals","NA","19p13.11","MEF2B, MEF2BNB-MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-?","rs58190593",0,58190593,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.02567,"[0.017-0.034] unit increase novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2010-02-12",20100581,"Shen L","2010-01-22","Neuroimage","www.ncbi.nlm.nih.gov/pubmed/20100581","Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort.","Brain imaging","175 European ancestry Alzheimer cases, 354 European ancestry amnestic mild cognitive impairment cases, 204 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(grey matter density of the right hippocampus)",null,null,"Illumina [530992]","N"]
[36,"rs190921611",19,45440529,"rs73045691","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,5886,4966,"rs73045691-?","rs73045691",0,73045691,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[4,"rs6657811",1,109807283,"rs6657811","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-T","rs6657811",0,6657811,"intron_variant",0,0.12,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.057,"[0.039-0.075] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[5,"rs12618122",2,21328825,"rs312945","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","2p24.1",null,"APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,61880,17964,"rs312945-A","rs312945",0,312945,"intergenic_variant",1,0.3051,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0091,"[0.0062-0.012] unit decrease","Affymetrix, Illumina [10000000] (imputed)","N"]
[6,"rs3817588",2,27743154,"rs780092","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-A","rs780092",0,780092,"intron_variant",0,0.68,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(TG)",0.08,"[0.060-0.100] unit increase","Affymetrix [~ 3700000] (imputed)","N"]
[6,"rs3817588",2,27743154,"rs780092","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-?","rs780092",0,780092,"intron_variant",0,null,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[6,"rs201353310",2,27861707,"rs11692692","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Systolic blood pressure","approximately 422,000 European ancestry individuals","NA","2p23.3",null,"GPN1",null,null,"ENSG00000198522",null,null,"rs11692692-?","rs11692692",0,11692692,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[7,"rs11681659",2,135954797,"rs1375131","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Mosquito bite size","84,724 European ancestry individuals","NA","2q21.3","Intergenic","ZRANB3",null,null,"ENSG00000121988",null,null,"rs1375131-T","rs1375131",0,1375131,"3_prime_UTR_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0345404,"[0.023-0.046] unit increase","Illumina [13520550] (imputed)","N"]
[11,"rs147662640",6,28411941,"rs67381177","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","ZSCAN23","ZSCAN23 - COX11P1","ENSG00000187987","ENSG00000231162",null,662,2809,"rs67381177-C","rs67381177",0,67381177,"regulatory_region_variant",1,0.07893365,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1.1776505,"[1.116557606-1.242086049]","Illumina [10439017] (imputed)","N"]
[11,"rs147662640",6,29223493,"rs3130825","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","6p22.1",null,"AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130825-?","rs3130825",0,3130825,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0208387,"[0.015-0.027] unit decrease","Affymetrix [20259828] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.8797,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02,"[0.014-0.026] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[16,"rs62466318",7,73040814,"rs34121855","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum albumin level","102,223 Japanese ancestry individuals","NA","7q11.23","MLXIPL, VPS37D","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,1941,41341,"rs34121855-?","rs34121855",0,34121855,"intergenic_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.04428,"[0.03-0.059] unit decrease","Illumina [6108953] (imputed)","N"]
[18,"rs7819706",8,19830921,"rs10096633","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","HDL cholesterol","7,813 African American individuals","4,323 African American and Afro-Caribbean individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-T","rs10096633",0,10096633,"regulatory_region_variant",1,0.43,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.101,"[0.068-0.134] unit increase","Affymetrix [~ 2740000] (imputed)","N"]
[18,"rs7819706",8,19830921,"rs10096633","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-A","rs10096633",0,10096633,"regulatory_region_variant",1,0.1,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(Indian)",13.66,"[9.21-18.11] unit decrease","Illumina [551825]","N"]
[19,"rs2954021",8,126491733,"rs2954031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-T","rs2954031",0,2954031,"intron_variant",0,0.4452,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02164556,"[0.015-0.029] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[19,"rs35309034",8,126498828,"rs4870941","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-?","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.15755,"[0.11-0.21] unit decrease","Affymetrix [7794483] (imputed)","N"]
[22,"rs538711822",10,64904071,"rs7073746","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Menarche (age at onset)","approximately 242,000 European ancestry individuals","NA","10q21.3",null,"NRBF2",null,null,"ENSG00000148572",null,null,"rs7073746-?","rs7073746",0,7073746,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-C","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.26,"[0.18-0.34] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[26,"rs12718462",11,116805064,"rs77204473","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum eosinophil basophil counts","171,771 European ancestry individuals","NA","11q23.3","SIK3","SIK3",null,null,"ENSG00000160584",null,null,"rs77204473-G","rs77204473",0,77204473,"intron_variant",0,0.0553,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0471667,"[0.032-0.062] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs1561458",15,44245931,"rs2929282","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","15q15.3","FRMD5","FRMD5",null,null,"ENSG00000171877",null,null,"rs2929282-T","rs2929282",0,2929282,"intron_variant",0,0.07,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.072,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[32,"rs16940904",17,44227393,"rs2696579","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular volume","172,433 European ancestry individuals","NA","17q21.31","KANSL1","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs2696579-A","rs2696579",0,2696579,"intron_variant",0,0.3375,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02406112,"[0.016-0.032] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs7245672",19,19670688,"rs7249692","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Monocyte count","170,721 European ancestry individuals","NA","19p13.11","PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,13220,1828,"rs7249692-C","rs7249692",0,7249692,"regulatory_region_variant",1,0.6719,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02296441,"[0.015-0.03] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","19q13.32","APOE, TOMM40","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-G","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.68,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.09,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[36,"rs157595",19,45416478,"rs584007","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs584007-?","rs584007",0,584007,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(females)",1.5096664,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-06-22",22558069,"Osman W","2012-04-27","PLoS One","www.ncbi.nlm.nih.gov/pubmed/22558069","Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.","Non-albumin protein levels","Up to 9,103 Japanese ancestry individuals","Up to 1,629 Japanese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.445,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(ALB)",0.08,"[0.053-0.107] unit decrease","Illumina [2178644] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"Affymetrix [344366]","N"]
[11,"rs147662640",6,28073881,"rs34662244","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","ZSCAN12P1 - ZNF602P","ENSG00000219891","ENSG00000219392",null,12439,9525,"rs34662244-A","rs34662244",0,34662244,"intergenic_variant",1,0.092,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(EA)",0.0691,"[0.046-0.092] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[11,"rs147662640",6,29342775,"rs3749971","2018-09-12",29942086,"Savage JE","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942086","Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.","Intelligence","269,867 European ancestry individuals","NA","6p22.1","NR","OR12D3, OR12D3, OR12D3, OR12D3, OR12D3, OR12D3, OR5V1, OR5V1, OR5V1, OR5V1, OR5V1",null,null,"ENSG00000224487, ENSG00000251394, ENSG00000204692, ENSG00000112462, ENSG00000250364, ENSG00000242022, ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000112461, ENSG00000243441",null,null,"rs3749971-A","rs3749971",0,3749971,"missense_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,5.929,"z-score increase","Affymetrix, Illumina [9295118] (imputed)","N"]
[16,"rs62466318",7,73026378,"rs17145750","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-T","rs17145750",0,17145750,"intron_variant",0,0.1611,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.02935932,"[0.02-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.874,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9183664,"rs4841133","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","8p23.1","RP11-115 J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841133-G","rs4841133",0,4841133,"non_coding_transcript_exon_variant",0,0.0929,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.11155177,"[0.075-0.148] mg/dl increase","Illumina [24111857] (imputed)","N"]
[18,"rs76722925",8,19919655,"rs4128744","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,94885,16970,"rs4128744-A","rs4128744",0,4128744,"regulatory_region_variant",1,0.11,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Indian)",2.21,"[1.48-2.94] unit increase","Illumina [551825]","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(EA)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Mean corpuscular volume","108,256 Japanese ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-?","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.02616,"[0.018-0.035] unit increase novel","Illumina [6108953] (imputed)","N"]
[29,"rs1561458",15,44218136,"rs481837","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs481837-C","rs481837",0,481837,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs6494005",15,58724524,"rs6494005","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs6494005-A","rs6494005",0,6494005,"non_coding_transcript_exon_variant",0,0.75,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(BMI unadjusted)",0.024,"[0.016-0.032] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[32,"rs16940904",17,43696159,"rs675600","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Myeloid white cell count","169,219 European ancestry individuals","NA","17q21.31","CRHR1-IT1, CRHR1, RP11-105N13.4","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,9875,1535,"rs675600-T","rs675600",0,675600,"intergenic_variant",1,0.2046,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.02733148,"[0.018-0.036] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs737338",19,11350488,"rs2278426","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","19p13.2","TSPAN16, SPC24, RAB3D, KANK2, DOCK6, LOC55908","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-?","rs2278426",0,2278426,"missense_variant",0,0.3,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.14,"[0.1-0.18] unit decrease","Illumina [1361436] (imputed)","N"]
[35,"rs11882123",19,19473445,"rs2905424","2014-03-18",23974872,"Ripke S","2013-08-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23974872","Genome-wide association analysis identifies 13 new risk loci for schizophrenia.","Schizophrenia","5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls","4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios","19p13.11","CILP2, PBX4, MAU2, GMIP, LPAR2, MIR640, NCAN, GATAD2A, HAPLN4, YJEFN3, NDUFA13, SUGP1, TM6SF2, TSSK6","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,3881,23190,"rs2905424-T","rs2905424",0,2905424,"intergenic_variant",1,0.348,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,1.092,"[1.06-1.12]","Affymetrix, Illumina [9871789]","N"]
[35,"rs58542926",19,19658472,"rs16996148","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","19p13.11","CILP2, NCAN","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-G","rs16996148",0,16996148,"intergenic_variant",1,0.92,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,6.1,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.911,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(East Asian)",0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs6129624",20,39159119,"rs1012167","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hair color","approximately 452,000 European ancestry individuals","NA","20q12",null,"AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,404122,155369,"rs1012167-?","rs1012167",0,1012167,"intergenic_variant",1,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[3,"rs1167998",1,62931632,"rs1167998","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1167998-?","rs1167998",0,1167998,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(VLDL.small, fasting)",1.505,"[NR] unit decrease","Illumina [335603]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(ALB)",0.085,"[0.056-0.114] unit decrease","Illumina [561583]","N"]
[6,"rs1260326",2,27741237,"rs780094","2015-04-24",25187374,"Hwang JY","2014-09-03","Diabetes","www.ncbi.nlm.nih.gov/pubmed/25187374","Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.","Fasting plasma glucose","24,740 East Asian ancestry individuals","21,345 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.052,"[0.034-0.070] unit increase","Affymetrix, Illumina [up to 2315813] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72971231,"rs13233571","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","7q11.23","BCL7B","BCL7B",null,null,"ENSG00000106635",null,null,"rs13233571-C","rs13233571",0,13233571,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.054,"[0.03-0.07] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73020337,"rs3812316","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women","up to 62,368 European ancestry women","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs3812316-C","rs3812316",0,3812316,"missense_variant",0,0.8809,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.0276,"[0.018-0.037] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[17,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,0.198,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(Hispanic)",0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121438844,"rs735396","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.39,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(DG11)",0.15703972,"[0.1-0.21] (zscore) increase","Illumina [NR]","N"]
[29,"rs28364531",15,42683787,"rs2412710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.1","NR","AC012651.1, CAPN3",null,null,"ENSG00000258461, ENSG00000092529",null,null,"rs2412710-G","rs2412710",0,2412710,"intron_variant",0,0.979,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(EA)",0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.075,"[0.05-0.1] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs58542926",19,19610596,"rs3794991","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19p13.11","GATAD2A, CILP2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs3794991-T","rs3794991",0,3794991,"intron_variant",0,0.0775,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.077,"[0.052-0.102] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[35,"rs892023",19,19663850,"rs892023","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Highest math class taken","430,445 European ancestry individuals","NA","19p13.11","Intergenic","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,6382,8666,"rs892023-A","rs892023",0,892023,"regulatory_region_variant",1,0.6077,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.0137,"[0.0092-0.0182] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[35,"rs12608822",19,19854296,"rs16996277","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","19p13.11",null,"AC011477.7",null,null,"ENSG00000275540",null,null,"rs16996277-?","rs16996277",0,16996277,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2012-03-14",22331829,"Chasman DI","2012-02-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22331829","Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.","Response to statins (LDL cholesterol change)","6,989 European ancestry individuals","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(baseline LDL-C)",5,"[3.43-6.57] mg/dL decrease","Illumina [814418]","N"]
[6,"rs77200710",2,27815510,"rs13022873","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","2p23.3","ZNF512","ZNF512, AC074091.1",null,null,"ENSG00000243943, ENSG00000259080",null,null,"rs13022873-A","rs13022873",0,13022873,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.17,"[0.11-0.23] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[11,"rs147662640",6,29248149,"rs3130834","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130834-C","rs3130834",0,3130834,"intron_variant",0,0.0955,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(EA)",0.0672,"[0.045-0.09] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","7q11.23","TBL2","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-?","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.04998,"[0.033-0.067] unit increase novel","Illumina [6108953] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.899,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(Hispanic)",0.137,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs34669405",8,19928160,"rs10106652","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103390,8465,"rs10106652-G","rs10106652",0,10106652,"intergenic_variant",1,0.744,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(Hispanic)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.02379,"[0.016-0.032] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2266788",11,116586283,"rs7350481","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA1, APOA4, APOA5, APOC3","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-T","rs7350481",0,7350481,"regulatory_region_variant",1,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.041,"[0.027-0.055] unit increase","Illumina [4642479] (imputed)","N"]
[32,"rs16940904",17,43696159,"rs675600","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte count","169,822 European ancestry individuals","NA","17q21.31","CRHR1-IT1, CRHR1, RP11-105N13.4","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,9875,1535,"rs675600-T","rs675600",0,675600,"intergenic_variant",1,0.2046,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.02673918,"[0.018-0.036] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,44205690,"rs4471723","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling guilty","373,380 European ancestry individuals","NA","17q21.31","NR","KANSL1, KANSL1, KANSL1",null,null,"ENSG00000120071, ENSG00000275867, ENSG00000278458",null,null,"rs4471723-T","rs4471723",0,4471723,"intron_variant",0,0.219254,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,5.84,"z score increase","NR [10847151] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-12-14",30336701,"Sanchez-Roige S","2018-10-19","Am J Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30336701","Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.","Alcohol use disorder (consumption score)","121,604 British ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.007,"[0.005-0.009] unit increase","NR [16213998]","N"]
[7,"rs11681659",2,136806959,"rs925966","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2q21.3","NR","DARS-AS1 - AC068492.1","ENSG00000231890","ENSG00000237262",null,26796,28503,"rs925966-C","rs925966",0,925966,"intergenic_variant",1,0.3847,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[8,"rs9884390",4,69339257,"rs34872892","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular volume","172,433 European ancestry individuals","NA","4q13.2","TMPRSS11E","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs34872892-G","rs34872892",0,34872892,"intron_variant",0,0.2108,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.02561079,"[0.017-0.034] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs10075801",5,131787137,"rs6866614","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Perceived unattractiveness to mosquitoes","16,576 European ancestry individuals","NA","5q31.1","C5orf56","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs6866614-G","rs6866614",0,6866614,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.135125,"[0.09-0.181] unit decrease","Illumina [7433384] (imputed)","N"]
[11,"rs147662640",6,29075088,"rs3129178","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","OR2J1 - OR2J3","ENSG00000225441","ENSG00000232178",null,4610,748,"rs3129178-A","rs3129178",0,3129178,"intergenic_variant",1,0.0951,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(EA)",0.0669,"[0.044-0.089] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[17,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.196,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(Hispanic)",0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19912370,"rs115849089","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin concentration","172,851 European ancestry individuals","NA","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.1165,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.0314433,"[0.021-0.042] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs56224630",11,116633862,"rs11820589","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs11820589-A","rs11820589",0,11820589,"missense_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(TG-GLUC)",0.32,"[0.20-0.44] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs936960",15,58765183,"rs7182229","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","15q21.3",null,"ALDH1A2, LIPC-AS1, LIPC",null,null,"ENSG00000128918, ENSG00000259293, ENSG00000166035",null,null,"rs7182229-?","rs7182229",0,7182229,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[32,"rs16940904",17,43696159,"rs675600","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","17q21.31","CRHR1-IT1, CRHR1, RP11-105N13.4","RPS26P8 - LINC02210","ENSG00000282238","ENSG00000204650",null,9875,1535,"rs675600-T","rs675600",0,675600,"intergenic_variant",1,0.2045,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.02652443,"[0.018-0.035] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[32,"rs35076622",17,43856458,"rs35076622","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","17q21.31","RP11-105N13.4","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs35076622-A","rs35076622",0,35076622,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,5.812,"z-score decrease","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[4,"rs629301",1,109821511,"rs602633","2017-04-05",27899403,"Jones GT","2016-11-29","Circ Res","www.ncbi.nlm.nih.gov/pubmed/27899403","Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.","Abdominal aortic aneurysm","4,972 European ancestry cases, 99,858 European ancestry controls","2,482 European ancestry cases, 2,750 cases, 2,645 European ancestry controls, 5,263 controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.199,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.14,"[1.09-1.19]","Affymetrix, Illumina [5363770] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-?","rs599839",0,599839,"regulatory_region_variant",1,null,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[11,"rs147662640",6,28619353,"rs114385935","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","ZBED9, LINC01623","LINC00533 - RPSAP2","ENSG00000249032","ENSG00000249814",null,2510,80441,"rs114385935-G","rs114385935",1,34724414,"intergenic_variant",1,0.079995652,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.1696258,"[1.109337082-1.233190796]","Illumina [10439017] (imputed)","N"]
[17,"rs9987289",8,9187242,"rs1461729","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs1461729-T","rs1461729",0,1461729,"intron_variant",0,0.116,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(AA)",0.0355,"[NR] unit decrease","Affymetrix [NR]","N"]
[18,"rs76722925",8,19860460,"rs79236614","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","Triglycerides","1,678 Mexican ancestry high triglyceride cases, 1,645 Mexican ancestry low triglyceride controls","2,129 Mexican ancestry high triglyceride cases, 2,985 Mexican ancestry low triglyceride controls, 903 Mexican ancestry individuals from 73 dyslipidemic families","8p21.3","SLC18A1, LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-?","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.89,"[1.49-2.38]","Illumina [1661241] (imputed)","N"]
[19,"rs33924196",8,126481475,"rs2980879","2012-05-10",22479202,"Dastani Z","2012-03-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22479202","Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.","Adiponectin levels","29,347 European ancestry individuals","10,536 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980879-T","rs2980879",0,2980879,"intron_variant",0,0.7,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.03,"[0.020-0.040] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[30,"rs1077835",15,58727325,"rs261332","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","15q21.3","RP11-355N15.1","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-G","rs261332",0,261332,"non_coding_transcript_exon_variant",0,0.792,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.02541862,"[0.017-0.034] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs11644601",16,15172118,"rs11644601","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","RRN3, PDXDC1",null,null,"ENSG00000085721, ENSG00000179889",null,null,"rs11644601-T","rs11644601",0,11644601,"intron_variant",0,"NR",{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2016-12-08",26833246,"Lu Y","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833246","New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.","Body fat percentage","Up to 31,457 European ancestry men, up to 35,030 European ancestry women, up to 8,259 Indian Asian ancestry men, up to 1,030 Indian Asian ancestry women, 973 Korean ancestry men, 1,360 Korean ancestry women, 154 African American men, 262 African American women","Up to 12,480 European ancestry men, up to 10,055 European ancestry women, 315 Jamaican ancestry men, 774 Jamaican ancestry women","19q13.32","TOMM40, APOE, APOC1, SH2B1, APOB48R","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-C","rs6857",0,6857,"3_prime_UTR_variant",0,0.83,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.048,"[0.032-0.064] body fat % increase","Affymetrix, Illumina, Perlegen [at least 1958375] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2017-02-17",27189021,"Cook JP","2016-05-18","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27189021","Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.","Type 2 diabetes","746 African American cases, 2,825 African American controls, 743 East Asian ancestry cases, 3,992 East Asian ancestry controls, 7,111 European ancestry cases, 49,688 European ancestry controls, 1,147 Latino cases, 5,352 Latino controls","12,171 European ancestry cases, 56,862 European ancestry controls","19q13.32","TOMM40, APOE","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-C","rs6857",0,6857,"3_prime_UTR_variant",0,0.844,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.12,"[1.08-1.16]","NR [at least 8497425] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease","10,874 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-G","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.17701,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.4227,"[-0.5965-1.4419] unit decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.6165,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.02097104,"[0.014-0.028] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[11,"rs147662640",6,28314880,"rs35016036","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Positive affect","410,603 European ancestry individuals","NA","6p22.1","NR","ZSCAN31",null,null,"ENSG00000235109",null,null,"rs35016036-T","rs35016036",0,35016036,"intron_variant",0,0.101417467242015,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.020720981,"[0.014-0.028] unit decrease","NR [NR]","N"]
[17,"rs9987289",8,9183596,"rs4841132","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0936,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,{"v":0.0006183,"d":"6.18E-04"},"[-0.00148-0.00272] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[19,"rs33924196",8,126484526,"rs2954026","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954026-G","rs2954026",0,2954026,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.16,"[0.10-0.22] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,65101207,"rs10740118","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","10q21.3","JMJD1C, NRBF2, REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10740118-C","rs10740118",0,10740118,"intron_variant",0,0.44,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.25,"[0.15-0.35] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.49,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(East Asian)",0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,43906828,"rs17689882","2015-11-03",25607358,"Hibar DP","2015-01-21","Nature","www.ncbi.nlm.nih.gov/pubmed/25607358","Common genetic variants influence human subcortical brain structures.","Subcortical brain region volumes","up to 13,171 European ancestry individuals","up to 15,130 European ancestry individuals, 545 Japanese ancestry individuals, 736 Mexican American individuals","17q21.31","CRHR1","CRHR1, LINC02210-CRHR1, LINC02210-CRHR1, MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000278232, ENSG00000263715, ENSG00000282456, ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs17689882-A","rs17689882",0,17689882,"intron_variant",0,0.22,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(Intracranial volume, EA)",13460.47,"[8891.61-18029.33] mm3 decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[35,"rs2285626",19,19425141,"rs12459676","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","19p13.11",null,"SUGP1",null,null,"ENSG00000105705",null,null,"rs12459676-?","rs12459676",0,12459676,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs117143374",21,40663255,"rs78175438","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Smoking status (ever vs never smokers)","518,633 European ancestry individuals","NA","21q22.2","HMGN1","BRWD1",null,null,"ENSG00000185658",null,null,"rs78175438-T","rs78175438",0,78175438,"intron_variant",0,0.8713,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.018702744,"[0.012-0.025] unit decrease","Affymetrix [11514654] (imputed)","N"]
[30,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.861,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,62922660,"rs4350231","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p31.3",null,"DOCK7",null,null,"ENSG00000116641",null,null,"rs4350231-?","rs4350231",0,4350231,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs1260326",2,27598097,"rs4665972","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","2p23.3","GCKR","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-T","rs4665972",0,4665972,"intron_variant",0,0.123,{"v":1E-8,"d":"1.00E-08"},8,"(AA)",0.065,"[NR] unit increase","Affymetrix [NR]","N"]
[6,"rs1728918",2,27635463,"rs1728918","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","2p23.3",null,"PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[9,"rs10075801",5,131676320,"rs1050152","2019-03-28",30643255,"Kristjansson RP","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643255","A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.","Nasal polyps","86 European ancestry whole-genome sequenced cases, 4,280 European ancestry cases, 13,941 European ancestry whole-genome sequenced controls, 700,740 European ancestry controls","NA","5q31.1","SLC22A4","SLC22A4, MIR3936HG",null,null,"ENSG00000197208, ENSG00000233006",null,null,"rs1050152-C","rs1050152",0,1050152,"missense_variant",0,0.594,{"v":1E-8,"d":"1.00E-08"},8,null,1.1363636,"[1.09-1.19]","Affymetrix, Illumina [up to 37123566] (imputed)","N"]
[16,"rs62466318",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","7q11.23","BAZ1B","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":1E-8,"d":"1.00E-08"},8,"(EA)",0.0294,"[0.019-0.039] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","8p23.1","RP-11-115 J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0925,{"v":1E-8,"d":"1.00E-08"},8,null,0.10894712,"[0.072-0.146] mg/dl increase","Illumina [24111857] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs326-T","rs326",0,326,"intron_variant",0,0.469,{"v":1E-8,"d":"1.00E-08"},8,"(AA)",0.041,"[NR] unit decrease","Affymetrix [NR]","N"]
[22,"rs538711822",10,65337153,"rs10822184","2012-10-28",22936694,"Jin G","2012-08-30","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/22936694","Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.","Androgen levels","3,225 European ancestry male individuals","NA","10q21.3","JMJD1C","REEP3",null,null,"ENSG00000165476",null,null,"rs10822184-T","rs10822184",0,10822184,"intron_variant",0,0.49,{"v":1E-8,"d":"1.00E-08"},8,"(serum testosterone)",0.058,"[0.038-0.078] unit decrease","Illumina [642461]","N"]
[26,"rs56224630",11,116652207,"rs12286037","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs12286037-C","rs12286037",0,12286037,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,"(TG-GLUC)",0.32,"[0.20-0.44] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[26,"rs688456",11,116780095,"rs75920871","2018-02-27",29292387,"Turley P","2018-01-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29292387","Multi-trait analysis of genome-wide association summary statistics using MTAG.","Subjective well-being","388,538 European ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs75920871-T","rs75920871",0,75920871,"intron_variant",0,0.1468,{"v":1E-8,"d":"1.00E-08"},8,null,0.0183,"[0.012-0.025] unit decrease","Illumina [NR] (imputed)","N"]
[28,"rs6602911",13,114542858,"rs9604573","2017-10-24",28898252,"Wheeler E","2017-09-12","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/28898252","Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.","Glycated hemoglobin levels","88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals","33,238 European ancestry individuals,  2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals","13q34","GAS6","GAS6-AS1, GAS6",null,null,"ENSG00000233695, ENSG00000183087",null,null,"rs9604573-T","rs9604573",0,9604573,"non_coding_transcript_exon_variant",0,0.2738,{"v":1E-8,"d":"1.00E-08"},8,"(European)",0.0101,"[0.0066-0.0136] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.78,{"v":1E-8,"d":"1.00E-08"},8,"(Hispanic)",0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15129459,"rs4985155","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.66,{"v":1E-8,"d":"1.00E-08"},8,"(men)",0.029,"unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43516402,"rs17631303","2013-08-02",23544013,"Couch FJ","2013-03-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23544013","Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.","Ovarian cancer in BRCA1 mutation carriers","683 European ancestry cases, 2,044 European ancestry controls","1,706 European ancestry cases, 10,258 European ancestry controls","17q21.31","intergenic","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs17631303-G","rs17631303",0,17631303,"intron_variant",0,0.19,{"v":1E-8,"d":"1.00E-08"},8,null,1.27,"[1.17-1.38]","Illumina [2568349] (imputed)","N"]
[32,"rs16940904",17,43682323,"rs186806998","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FVC)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31",null,"MAPK8IP1P2 - RPS26P8","ENSG00000263503","ENSG00000282238",null,2617,3614,"rs186806998-?","rs186806998",1,56383763,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,30.52,"[20.01-41.03] unit increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[33,"rs763363223",18,47193943,"rs34770920","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","18q21.1",null,"SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,16413,72250,"rs34770920-?","rs34770920",0,34770920,"regulatory_region_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.833,{"v":1E-8,"d":"1.00E-08"},8,"(AA)",0.194,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","19q13.32","LOC100129500","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-C","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.24,"[0.16-0.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[38,"rs117143374",21,40663253,"rs77217252","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Smoking status","approximately 458,000 European ancestry individuals","NA","21q22.2",null,"BRWD1",null,null,"ENSG00000185658",null,null,"rs77217252-?","rs77217252",0,77217252,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs952275",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.675,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","Metabolic traits","4,763 Northern Finnish founder individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs673548-A","rs673548",0,673548,"intron_variant",0,0.27,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(TG)",0.08,"[0.05-0.11] mmol/l decrease","Illumina [329091]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum albumin level","Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.56,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Japanese)",0.027,"[0.017-0.037] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2016-01-22",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in obese individuals","4,613 European ancestry male individuals, 4,690 European ancestry female individuals, 142 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.6,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.085,"[0.056-0.114] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.369,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.467,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","2q21.3","MCM6","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.6486,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.0217,"[0.014-0.029] unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[8,"rs1377869",4,69349893,"rs138151052","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","4q13.2","NR","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs138151052-T","rs138151052",1,13114070,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,28776117,"rs4324798","2009-11-09",19836008,"Landi MT","2009-10-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/19836008","A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.","Lung adenocarcinoma","5,739 European ancestry cases, 5,848 European ancestry controls","7,561 European ancestry cases, 13,818 European ancestry controls","6p22.1","TRNAA-UGC","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,24336,29529,"rs4324798-A","rs4324798",0,4324798,"intergenic_variant",1,0.09,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.16,"[1.09-1.24]","Illumina [515922]","N"]
[11,"rs147662640",6,29260431,"rs3117425","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","6p22.1","NR","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3117425-T","rs3117425",0,3117425,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.02019,"[0.013-0.027] unit decrease","Affymetrix [10847151] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","Triglyceride levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","8p21.3","LPL, RPL30P9","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,null,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Japanese)",0.23,"[0.15-0.31] unit decrease","Illumina [1294241]","N"]
[19,"rs2980884",8,126474356,"rs2980884","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","White blood cell count (basophil)","62,076 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,23709,4825,"rs2980884-?","rs2980884",0,2980884,"intergenic_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.03688,"[0.024-0.05] unit increase novel","Illumina [6108953] (imputed)","N"]
[20,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65027610,"rs10761731","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-A","rs10761731",0,10761731,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"NR [2501543] (imputed)","N"]
[23,"rs4418728",10,94839642,"rs2068888","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","10q23.33","CYP26A1","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-A","rs2068888",0,2068888,"regulatory_region_variant",1,0.47,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,2.28,"[1.54-3.02] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[23,"rs4418728",10,94839724,"rs4418728","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Diastolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,2077,26905,"rs4418728-T","rs4418728",0,4418728,"TF_binding_site_variant",1,0.6242,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.1975,"[0.13-0.27] unit decrease","Illumina [6200000] (imputed)","N"]
[26,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.35,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs28364531",15,42683787,"rs2412710","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","15q15.1","CAPN3","AC012651.1, CAPN3",null,null,"ENSG00000258461, ENSG00000092529",null,null,"rs2412710-A","rs2412710",0,2412710,"intron_variant",0,0.02,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,7,"[4.08-9.92] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs1601935",15,58674695,"rs4775041","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-C","rs4775041",0,4775041,"intron_variant",0,0.33,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,3.62,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.548,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs74019428",15,58692681,"rs56903760","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","15q21.3","AQP9, LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs56903760-?","rs56903760",0,56903760,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0334,"[0.022-0.045] unit increase novel","Illumina [6108953] (imputed)","N"]
[32,"rs16940904",17,43666492,"rs112010353","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Self-reported math ability","564,698 European ancestry individuals","NA","17q21.31","Intergenic","AC126544.2 - AC126544.1","ENSG00000285668","ENSG00000280022",null,747,3495,"rs112010353-C","rs112010353",0,112010353,"intergenic_variant",1,0.8237,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0143,"[0.0092-0.0194] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[32,"rs35076622",17,43851498,"rs35909029","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","17q21.31","NR","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs35909029T","rs35909029",0,35909029,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.01299,"[0.0085-0.0175] unit increase","Affymetrix [10847151] (imputed)","N"]
[32,"rs16940904",17,43927290,"rs17769552","2018-07-09",29691431,"Tikkanen E","2018-04-24","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29691431","Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.","Hand grip strength","334,825 British ancestry individuals","NA","17q21.31","SPPL2C","MAPT-AS1, MAPT-AS1, MAPT-AS1",null,null,"ENSG00000264589, ENSG00000281578, ENSG00000282067",null,null,"rs17769552-A","rs17769552",0,17769552,"intron_variant",0,0.2235,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,2E-3,"[0.0014-0.0026] unit decrease","Affymetrix [15275733] (imputed)","N"]
[32,"rs199500",17,44863133,"rs916888","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs916888-T","rs916888",0,916888,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.019683955,"[0.013-0.027] unit increase","Affymetrix [NR]","N"]
[33,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(HDL-C.assay, fasting)",1.33,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs58542926",19,19494483,"rs150268548","2016-12-20",27002377,"Irvin MR","2016-07-01","Pharmacogenet Genomics","www.ncbi.nlm.nih.gov/pubmed/27002377","A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies.","Response to fenofibrate (LDL cholesterol levels)","1,594 European ancestry individuals","350 Hispanic individuals, 138 African American individuals","19p13.11","MAU2, GATAD2A","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,24919,2152,"rs150268548-G","rs150268548",0,150268548,"intergenic_variant",1,0.92,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(European)",0.05,"[0.011-0.089] unit decrease","Affymetrix [6982258] (imputed)","N"]
[35,"19:19510831_AT_A",19,19545099,"rs4808199","2018-02-20",29385134,"Kawaguchi T","2018-01-31","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29385134","Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.","Nonalcoholic fatty liver disease","902 Japanese ancestry cases, 7,672 Japanese ancestry controls","NA","19p13.11","GATAD2A, NCAN, TM6SF2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808199-A","rs4808199",0,4808199,"intron_variant",0,0.27,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.37,"[1.23-1.53]","Illumina [93606]","N"]
[4,"rs629301",1,109821511,"rs602633","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","1p13.3","CLESR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.217,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.015,"[0.0097-0.0203] unit decrease","Affymetrix [11535925] (imputed)","N"]
[5,"rs10184054",2,21206183,"rs6754295","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,121650,16002,"rs6754295-C","rs6754295",0,6754295,"intergenic_variant",1,0.25,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.08,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27748624,"rs1260333","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2073,11629,"rs1260333-A","rs1260333",0,1260333,"intergenic_variant",1,0.52,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.773,"[1.15-2.4] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[11,"rs9257779",6,28768113,"rs116668069","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","ZBED9, LINC01623","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,16332,37533,"rs116668069-A","rs116668069",1,7766107,"intergenic_variant",1,0.135876166,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.1370234,"[1.08637948-1.19002823]","Illumina [10439017] (imputed)","N"]
[11,"rs147662640",6,29356331,"rs9257809","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","OR5V1, OR5V1, OR5V1, OR5V1, OR5V1",null,null,"ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000112461, ENSG00000243441",null,null,"rs9257809-G","rs9257809",0,9257809,"intron_variant",0,0.1004,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(EA)",0.0627,"[0.041-0.085] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[16,"rs62466318",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.865,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19852310,"rs17411031","2019-01-11",30054458,"Xue A","2018-07-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30054458","Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.","Type 2 diabetes","61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27540,84315,"rs17411031-G","rs17411031",0,17411031,"regulatory_region_variant",1,0.261729325660064,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.045,"[0.029-0.061] unit decrease","NR [5035015] (imputed)","N"]
[22,"rs538711822",10,65365385,"rs1896995","2018-02-23",29326435,"Hill WD","2018-01-11","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29326435","A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.","Intelligence (MTAG)","120,934 British ancestry individuals, 127,548 individuals","NA","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs1896995-T","rs1896995",0,1896995,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.017029727,"[0.011-0.023] unit increase","Affymetrix [NR]","N"]
[25,"rs673335",11,75455021,"rs499974","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q13.5","NR","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1550,14479,"rs499974-C","rs499974",0,499974,"regulatory_region_variant",1,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121424861,"rs7310409","2011-01-16",21196492,"Okada Y","2010-12-31","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21196492","Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.","C-reactive protein","10,112 Japanese ancestry individuals","2,742 Japanese ancestry individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.47,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.07,"[0.04-0.10] unit increase","Illumina [477784]","N"]
[28,"rs6602911",13,114547372,"rs6602911","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","13q34","GAS6","GAS6, GAS6-AS1",null,null,"ENSG00000183087, ENSG00000233695",null,null,"rs6602911-T","rs6602911",0,6602911,"non_coding_transcript_exon_variant",0,0.4294,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.0154,"[0.0099-0.0209] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.777,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs34936342",16,14753259,"rs34936342","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","16p13.12",null,"BFAR, BFAR",null,null,"ENSG00000103429, ENSG00000275618",null,null,"rs34936342-?","rs34936342",0,34936342,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs142158911",19,11188153,"rs55791371","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs55791371-A","rs55791371",0,55791371,"intron_variant",0,0.9,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.11,"[1.07-1.15]","Affymetrix, Illumina [8600000] (imputed)","N"]
[35,"19:19756073_AGCC_A",19,19786099,"rs58434384","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","19p13.11",null,"ZNF101",null,null,"ENSG00000181896",null,null,"rs58434384-?","rs58434384",0,58434384,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.905,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(East Asian)",0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs4818005",21,40520783,"rs7281463","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Smoking behaviour (cigarettes smoked per day)","up to 377,334 European ancestry individuals","NA","21q22.2","NR","RPL23AP12 - PCBP2P1","ENSG00000228861","ENSG00000235701",null,20817,22273,"rs7281463-C","rs7281463",0,7281463,"intergenic_variant",1,0.413,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.013677968,"[0.0088-0.0185] unit increase","NR [~ 10000000] (imputed)","N"]
[5,"rs10184054",2,21123352,"rs6711016","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,61931,75721,"rs6711016-C","rs6711016",0,6711016,"regulatory_region_variant",1,0.71,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(TG)",0.08,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.742,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(Hispanic)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs201353310",2,27855924,"rs6547741","2017-03-31",27749845,"Lesseur C","2016-10-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27749845","Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.","Oral cavity cancer","2,717 European ancestry cases, 273 cases, 5,984 European ancestry controls, 601 controls","NA","2p23.3","GPN1, C2orf16, ZNF512, CCDC121","GPN1, AC074091.1",null,null,"ENSG00000198522, ENSG00000259080",null,null,"rs6547741-G","rs6547741",0,6547741,"intron_variant",0,0.46,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,1.1983223,"NR","Illumina [7574753] (imputed)","N"]
[9,"rs10075801",5,131402738,"rs3091338","2012-04-03",22412388,"Kenny EE","2012-03-08","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22412388","A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.","Crohn's disease","737 Ashkenazi Jewish cases, 2,257  Ashkenazi Jewish controls","971 Ashkenazi Jewish cases, 2,124 Ashkenazi Jewish controls","5q31.1","IL3, ACSL6, P4HA2, PDLIM4, SLC22A4","IL3 - CSF2","ENSG00000164399","ENSG00000164400",null,3841,6745,"rs3091338-T","rs3091338",0,3091338,"intergenic_variant",1,0.328,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,1.23,"[1.08-1.42]","Affymetrix, Illumina [1060934] (imputed)","N"]
[16,"rs62466318",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(EA)",0.0319,"[0.021-0.043] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73026151,"rs13234378","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13234378-A","rs13234378",0,13234378,"intron_variant",0,0.8858,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.0235,"[0.015-0.032] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs538711822",10,65314711,"rs2163188","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","10q21.3","NR","REEP3",null,null,"ENSG00000165476",null,null,"rs2163188-G","rs2163188",0,2163188,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.015,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[23,"rs4418728",10,94839724,"rs4418728","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum total protein level","113,509 Japanese ancestry individuals","NA","10q23.33","CYP26A1, MYOF","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,2077,26905,"rs4418728-?","rs4418728",0,4418728,"TF_binding_site_variant",1,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.02376,"[0.015-0.032] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Triglycerides-Blood Pressure (TG-BP)","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-C","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.37,"[0.23-0.51] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[27,"rs7970695",12,121438844,"rs735396","2011-01-15",21203500,"Lauc G","2010-12-23","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21203500","Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.","N-glycan levels","2,559 European ancestry individuals","NA","12q24.31","OASL, C12orf43, HNF1A","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.38,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(DG11)",0.17,"[0.11-0.23] unit increase","Illumina [~ 300000]","N"]
[32,"rs16940904",17,44096553,"rs62062288","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Worry too long after an embarrassing experience","367,725 European ancestry individuals","NA","17q21.31","NR","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs62062288-A","rs62062288",0,62062288,"intron_variant",0,0.211505,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,5.5,"z score increase","NR [10847151] (imputed)","N"]
[32,"rs199460",17,44837217,"rs199529","2018-10-10",30054594,"MacGregor S","2018-07-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30054594","Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.","Intraocular pressure","133,492 European ancestry individuals","NA","17q21.31","NSF","NSF - WNT3","ENSG00000073969","ENSG00000277641",null,2387,2655,"rs199529-?","rs199529",0,199529,"intergenic_variant",1,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.083,"[0.053-0.113] unit decrease","Affymetrix, Illumina [up to 40000000] (imputed)","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","19p13.11","CILP2, ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.09,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.07,"[0.04-0.10] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-A","rs56131196",0,56131196,"intergenic_variant",1,0.16,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,1.09,"[1.06-1.12]","Affymetrix, Illumina [8600000] (imputed)","N"]
[38,"rs4818005",21,40628765,"rs1541102","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","21q22.2","BRWD1","BRWD1",null,null,"ENSG00000185658",null,null,"rs1541102-T","rs1541102",0,1541102,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,5.481,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.334,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(AA)",0.148,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741072,"rs780096","2018-03-05",29304378,"Medina-Gomez C","2018-01-04","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29304378","Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.","Total body bone mineral density","56,284 European ancestry individuals, up to 1,333 African American individuals, up to 9,328 admixed individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780096-C","rs780096",0,780096,"intron_variant",0,0.4406,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0311,"unit decrease","Affymetrix, Illumina [~ 23700000] (imputed)","N"]
[6,"rs1870325",2,28020157,"rs12623170","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","2p23.2","RBKS","RBKS, MRPL33",null,null,"ENSG00000171174, ENSG00000243147",null,null,"rs12623170-C","rs12623170",0,12623170,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,1.0604454,"[1.04-1.08]","Illumina [6627481] (imputed)","N"]
[18,"rs76722925",8,19885934,"rs138022915","2017-04-04",27723756,"Wang J","2016-10-10","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27723756","Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.","Gut microbiota (beta diversity)","1,812 European ancestry individuals","371 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,61164,50691,"rs138022915-?","rs138022915",1,11984698,"intergenic_variant",1,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.73,"NR percent increase","Affymetrix, Illumina [6344846] (imputed)","N"]
[19,"rs33924196",8,126507308,"rs2980888","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","8q24.13","Intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980888-T","rs2980888",0,2980888,"intron_variant",0,0.285,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0506,"[NR] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[30,"rs1077835",15,58727325,"rs261332","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Total cholesterol levels","up to 33,431 European ancestry individuals","NA","15q21.3","LIPC, LIPC-AS1","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-T","rs261332",0,261332,"non_coding_transcript_exon_variant",0,0.1955,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.96994877,"[0.62-1.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs199460",17,44764775,"rs199460","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","17q21.31","NR","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199460-?","rs199460",0,199460,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,5.447,"z-score increase","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,null,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.06041999,"[NR] unit increase","Illumina [575353]","N"]
[36,"rs157595",19,45425460,"rs157595","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-?","rs157595",0,157595,"intergenic_variant",1,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[36,"rs9304644",19,45450033,"rs9304644","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC2, APOC4-APOC2",null,null,"ENSG00000234906, ENSG00000224916",null,null,"rs9304644-?","rs9304644",0,9304644,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[36,"rs4803791",19,45523583,"rs4803791","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","RELB",null,null,"ENSG00000104856",null,null,"rs4803791-?","rs4803791",0,4803791,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[3,"rs1167998",1,62996838,"rs1168013","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168013-G","rs1168013",0,1168013,"intron_variant",0,0.65,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.04,"[0.03-0.05] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[5,"rs432483",2,21428049,"rs312053","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","2p24.1",null,"AC067959.1 - AC018742.1","ENSG00000271629","ENSG00000233005",null,6281,15998,"rs312053-?","rs312053",0,312053,"intergenic_variant",1,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[16,"rs62466318",7,73005776,"rs35866503","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,12655,1748,"rs35866503-C","rs35866503",0,35866503,"intergenic_variant",1,0.82,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.015,"[0.0091-0.0209] unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[26,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.281,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(Hispanic)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2015-06-27",25411281,"Dashti HS","2014-10-08","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25411281","Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations.","Circulating phylloquinone levels","2,138 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.15,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(Model 1)",0.23,"[0.15-0.31] unit increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.941,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(AA)",0.258,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58678512,"rs10468017","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(HDLC-WC)",0.16,"[0.10-0.22] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43513441,"rs11012","2010-02-05",20070850,"Edwards TL","2010-01-13","Ann Hum Genet","www.ncbi.nlm.nih.gov/pubmed/20070850","Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.","Parkinson's disease","1,752 European ancestry cases, 1,745 European ancestry controls","NA","17q21.31","MAPT, PLEKHM1, IMP5","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs11012-T","rs11012",0,11012,"3_prime_UTR_variant",0,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,1.43,"[1.27-1.61]","Illumina [495715] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2017-08-21",28334935,"Raffield LM","2017-05-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334935","Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?","Iron status biomarkers (total iron binding capacity)","12,586 Hispanic/Latino individuals","NA","8p23.1","LOC157273, PP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.116,"[0.073-0.159] unit decrease","Illumina [27700000] (imputed)","N"]
[17,"rs9987289",8,9183596,"rs4841132","2017-08-21",28334935,"Raffield LM","2017-05-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334935","Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?","Iron status biomarkers (total iron binding capacity)","12,586 Hispanic/Latino individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.116,"unit decrease","Illumina [27700000] (imputed)","N"]
[35,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2019-03-28",30510157,"Franceschini N","2018-12-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30510157","GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.","Carotid intima media thickness","Up to 71,128 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.18,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.0487,"[0.047-0.05] unit decrease","Affymetrix, Illumina [9574088] (imputed)","N"]
[11,"rs147662640",6,29254982,"rs139244745","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","OR2J2, OR14J1","AL672167.1",null,null,"ENSG00000197171",null,null,"rs139244745-G","rs139244745",1,9257681,"intron_variant",0,0.088075082,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,1.162069,"[1.100123412-1.227502509]","Illumina [10439017] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women","up to 62,368 European ancestry women","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.876,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.0264,"[0.017-0.036] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[26,"rs486394",11,116526322,"rs486394","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","11q23.3","LOC101929011","AP000770.1",null,null,"ENSG00000237937",null,null,"rs486394-?","rs486394",0,486394,"intron_variant",0,"NR",{"v":8e-08,"d":"8.00E-08"},7.09691001300805,{"$nulls":3},"Affymetrix [344366]","N"]
[32,"rs16940904",17,43991272,"rs17563986","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability","107,207 European ancestry individuals","NA","17q21.31","MAPT","MAPT, MAPT, MAPT",null,null,"ENSG00000277956, ENSG00000276155, ENSG00000186868",null,null,"rs17563986-?","rs17563986",0,17563986,"intron_variant",0,"NR",{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,5.368,"z score increase","Affymetrix, Illumina [7357080] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.371,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(Hispanic)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[11,"rs147662640",6,28974265,"rs115287935","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","ZNF311, LOC100129636","ZNF311 - OR2AD1P","ENSG00000197935","ENSG00000233650",null,1172,20192,"rs115287935-T","rs115287935",1,3129794,"intergenic_variant",1,0.08238902,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,1.1647499,"[1.101314463-1.231839236]","Illumina [10439017] (imputed)","N"]
[30,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.601,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(East Asian)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs61061000",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Mean arterial pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.3413,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(Japanese)",0.3118,"[0.2-0.43] unit increase","Illumina [6200000] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2008-06-16",18179892,"Wallace C","2008-01-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18179892","Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.","LDL cholesterol","1,955 European ancestry hypertensive individuals","2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.24,{"v":1e-07,"d":"1.00E-07"},7,null,0.95,"[0.93-0.97] mMol/l increase","Affymetrix [400496]","N"]
[5,"rs10184054",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.742,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs1377869",4,69349893,"rs138151052","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","4q13.2","NR","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs138151052-T","rs138151052",1,13114070,"intron_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,0.027,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs10075801",5,131770805,"rs2188962","2010-07-12",20570966,"McGovern DP","2010-06-22","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20570966","Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.","Crohn's disease","896 European ancestry cases, 3,204 European ancestry controls","1,174 European ancestry cases, 357 European ancestry controls","5q31.1","IBD5","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs2188962-?","rs2188962",0,2188962,"intron_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,1.36,"[1.21-1.52]","Illumina [304825]","N"]
[13,"rs56393506",6,161089307,"rs56393506","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (large artery atherosclerosis)","4,373 European ancestry cases, 406,111 European ancestry controls, 1,626 East Asian ancestry cases, 28,195 East Asian ancestry controls, 355 South Asian ancestry cases, 6,707 South Asian ancestry controls, 259 African American cases, 15,146 African American controls, 34 Asian ancestry cases, 333 Asian ancestry controls, 41 Latin American cases, 692 Latin American controls","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,0.16,{"v":1e-07,"d":"1.00E-07"},7,null,1.17,"[1.10-1.24]","NR [~ 8000000] (imputed)","N"]
[16,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.854,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs34669405",8,19928013,"rs6999158","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103243,8612,"rs6999158-T","rs6999158",0,6999158,"intergenic_variant",1,0.727,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5,{"v":1e-07,"d":"1.00E-07"},7,null,0.02,"[0.01-0.03] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-07,"d":"1.00E-07"},7,"(EA, women)",0.0502,"[0.032-0.069] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,64878118,"rs6479877","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Vascular endothelial growth factor levels","7,118 Finnish ancestry individuals","NA","10q21.3","NR","RNU6-543P - AL590502.1","ENSG00000199446","ENSG00000224301",null,8112,5580,"rs6479877-G","rs6479877",0,6479877,"intergenic_variant",1,null,{"v":1e-07,"d":"1.00E-07"},7,null,0.0897,"[0.056-0.123] SD units increase","NR [10700000] (imputed)","N"]
[23,"rs4418728",10,94839724,"rs4418728","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Mean arterial pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,2077,26905,"rs4418728-T","rs4418728",0,4418728,"TF_binding_site_variant",1,0.62,{"v":1e-07,"d":"1.00E-07"},7,"(East Asian)",0.2536,"[0.16-0.35] unit decrease","Illumina [6200000] (imputed)","N"]
[26,"rs12718462",11,116782974,"rs11216185","2012-03-03",22306654,"Feenstra B","2012-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22306654","Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.","Infantile hypertrophic pyloric stenosis","1,001 European ancestry cases, 2,401 European ancestry controls","796 European ancestry cases, 876 European ancestry controls","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs11216185-G","rs11216185",0,11216185,"intron_variant",0,0.05,{"v":1e-07,"d":"1.00E-07"},7,null,1.57,"[1.33-1.86]","Illumina [523420]","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.676,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.569,{"v":1e-07,"d":"1.00E-07"},7,"(AA)",0.114,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs61061000",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Diastolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.3413,{"v":1e-07,"d":"1.00E-07"},7,"(Japanese)",0.2807,"[0.18-0.38] unit increase","Illumina [6200000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2010-02-12",20100581,"Shen L","2010-01-22","Neuroimage","www.ncbi.nlm.nih.gov/pubmed/20100581","Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort.","Brain imaging","175 European ancestry Alzheimer cases, 354 European ancestry amnestic mild cognitive impairment cases, 204 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,"(multiple phenotypes)",null,null,"Illumina [530992]","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.897,{"v":1e-07,"d":"1.00E-07"},7,"(East Asian)",0.147,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.629,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21204025,"rs6544366","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,119492,18160,"rs6544366-T","rs6544366",0,6544366,"intergenic_variant",1,0.22,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[5,"rs952275",2,21232195,"rs693","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs693-A","rs693",0,693,"synonymous_variant",0,0.48,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.08,"[0.04-0.12] unit increase","Affymetrix [389878]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-03-20",27588450,"Mahajan A","2016-09-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27588450","Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.","Glomerular filtration rate","23,553 European ancestry individuals, 23,536 Japanese individuals, 16,325 Hispanic individuals, 8,224 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.83,"[0.52-1.14] unit decrease","Affymetrix, Illumina [at least 6581000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Leucine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.049,"[0.023-0.075] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.5895,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.0552,"[0.035-0.076] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[6,"rs3817588",2,27743154,"rs780092","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglycerides","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-G","rs780092",0,780092,"intron_variant",0,0.321,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Filipino)",0.186,"[0.12-0.26] unit decrease","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[9,"rs200800380",5,131677997,"rs272869","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist circumference adjusted for BMI in non-smokers","77,113 European ancestry women, 47,319 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men","16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men","5q31.1","SLC22A4","MIR3936HG, SLC22A4",null,null,"ENSG00000233006, ENSG00000197208",null,null,"rs272869-A","rs272869",0,272869,"intron_variant",0,0.4005,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.0205,"[0.013-0.028] unit decrease","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[9,"rs10075801",5,131723288,"rs2073643","2010-10-14",20860503,"Moffatt MF","2010-09-23","N Engl J Med","www.ncbi.nlm.nih.gov/pubmed/20860503","A large-scale, consortium-based genomewide association study of asthma.","Asthma","10,365 cases, 16,110 controls","NA","5q31.1","SLC22A5","SLC22A5",null,null,"ENSG00000197375",null,null,"rs2073643-T","rs2073643",0,2073643,"intron_variant",0,0.45,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,1.11,"[1.06-1.15]","Illumina [582892]","N"]
[17,"rs9987289",8,9183358,"rs9987289","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","8p23.1","PPP1R3B, LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.09,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.05,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.903,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,1.05,"[1.03-1.07]","Affymetrix, Illumina [247470]","N"]
[26,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.225,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(South Asian)",0.339,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs56224630",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.897,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.127,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.274,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(East Asian)",0.092,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs143875230",15,43099550,"rs149492745","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.2","NR","TTBK2",null,null,"ENSG00000128881",null,null,"rs149492745-C","rs149492745",0,149492745,"intron_variant",0,0.972,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.228,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs199460",17,44368212,"rs2957297","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","17q21.31","NR","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2957297-?","rs2957297",0,2957297,"intron_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,5.231,"z-score decrease","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs429358",19,45410002,"rs769449","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (combined parental age at death)","45,627 middle-aged British individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.058581,"[0.036-0.081] unit increase","Affymetrix [9658292] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.905,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(East Asian)",0.152,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.1978,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.1028,"[0.064-0.142] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(East Asian)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.247,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Hispanic)",0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.754,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Hispanic)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72864869,"rs714052","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","7q11.23","MIXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-G","rs714052",0,714052,"intron_variant",0,0.11,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.123,"[0.076-0.170] unit decrease","Illumina [561583]","N"]
[16,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.908,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(East Asian)",0.13,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs34669405",8,19928013,"rs6999158","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,103243,8612,"rs6999158-T","rs6999158",0,6999158,"intergenic_variant",1,0.727,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Hispanic)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65016174,"rs7088799","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interleukin-10 levels","7,681 Finnish ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7088799-G","rs7088799",0,7088799,"intron_variant",0,null,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.0852,"[0.052-0.118] SD units increase","NR [10700000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.878,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(APOC3)",0.194,"[0.12-0.27] unit decrease","Illumina [> 1000000] (imputed)","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs199460",17,44788310,"rs183211","2011-09-14",21812969,"Liu X","2011-08-03","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21812969","Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.","Parkinson's disease","268 Ashkenazi Jewish cases, 178 Ashkenazi Jewish controls","1,782 European ancestry cases, 1,658 European ancestry controls","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs183211-T","rs183211",0,183211,"intron_variant",0,0.24,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,{"$nulls":3},"Illumina [525124]","N"]
[32,"rs16940904",17,44847834,"rs199525","2018-11-01",30061609,"Wyss AB","2018-07-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30061609","Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.","Lung function (FVC)","60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals",null,"17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199525-T","rs199525",0,199525,"intron_variant",0,0.79,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",20.03,"[12.41-27.65] unit increase","Affymetrix, Illumina [10900000] (imputed)","N"]
[35,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(males)",0.0174,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.762,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21198900,"rs11902417","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,114367,23285,"rs11902417-G","rs11902417",0,11902417,"intergenic_variant",1,0.78,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.02,"[0.01-0.03] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[5,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107665978,"rs1800978","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.8664,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.0438,"[0.027-0.061] unit increase","NR [8041861] (imputed)","N"]
[22,"rs538711822",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.067,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(EA)",0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs157580-G","rs157580",0,157580,"intron_variant",0,0.33,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.06,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[5,"rs10184054",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.247,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.757,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2017-12-11",22885922,"Morris AP","2012-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22885922","Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.","Type 2 diabetes","6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls","12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.613751766081311,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,1.06,"[1.04-1.09]","Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[13,"rs10455872",6,161010118,"rs10455872","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (father's age at death)","317,652 British ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.92,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.0247,"[0.015-0.034] unit increase","Affymetrix [11535925] (imputed)","N"]
[27,"rs7970695",12,121435587,"rs2259816","2009-03-01",19198612,"Erdmann J","2009-02-08","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19198612","New susceptibility locus for coronary artery disease on chromosome 3q22.3.","Coronary heart disease","1,222 European ancestry cases, 1,298 European ancestry controls","18,185 European ancestry cases, 20,068 European ancestry controls","12q24.31","C12orf43, HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs2259816-T","rs2259816",0,2259816,"synonymous_variant",0,0.36,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,1.08,"[1.05-1.11]","Affymetrix [567119]","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.294,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11882123",19,19446936,"rs769267","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs769267-?","rs769267",0,769267,"synonymous_variant",0,"NR",{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.0434,"[0.027-0.06] unit increase","Illumina [at least 560000] (imputed)","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.906,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.028,"[0.017-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[36,"rs190921611",19,45448465,"rs5167","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-T","rs5167",0,5167,"missense_variant",0,0.643,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(EA)",0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs62466318",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.906,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(East Asian)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","HDL cholesterol levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","8p21.3","LPL, RPL30P9","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(Japanese)",0.24,"[0.15-0.33] unit increase","Illumina [1294241]","N"]
[25,"rs673335",11,75455021,"rs499974","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q13.5","NR","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1550,14479,"rs499974-C","rs499974",0,499974,"regulatory_region_variant",1,0.832,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15129459,"rs4985155","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.665,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA, men)",0.021,"[0.013-0.029] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[36,"rs429358",19,45392254,"rs6857","2017-06-27",28183528,"Jun GR","2017-02-06","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/28183528","Transethnic genome-wide scan identifies novel Alzheimer's disease loci.","Alzheimer's disease","13,100 European ancestry cases, 13,220 European ancestry controls, 1,472 African American cases, 3,511 African American controls, 951 Japanese ancestry cases, 894 Japanese ancestry controls, 51 Israeli-Arab ancestry cases, 64 Israeli-Arab ancestry controls","5,813 European ancestry cases, 20,474 European ancestry controls","19q13.32","NR","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(AA)",1.27,"[1.15-1.40]","NR [NR]","N"]
[3,"rs1167998",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.656,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs10184054",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.244,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21232195,"rs693","2017-11-01",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","LDL cholesterol levels","2,601 European ancestry type 2 diabetes cases and controls","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs693-A","rs693",0,693,"synonymous_variant",0,0.49,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,1,"(% variance) increase","Affymetrix [389878]","N"]
[22,"rs538711822",10,64963449,"rs4379723","2013-03-15",23263863,"Li J","2012-12-20","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/23263863","GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.","Platelet count","7,943 African American children, 6,234 European ancestry children","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs4379723-T","rs4379723",0,4379723,"intron_variant",0,"NR",{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,5.4297,"[3.28-7.58] unit decrease","Illumina [544917]","N"]
[22,"rs538711822",10,65203808,"rs3999089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs3999089-A","rs3999089",0,3999089,"intron_variant",0,0.513,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(EA)",0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Indian)",null,null,"Illumina [551825]","N"]
[32,"rs16940904",17,44859144,"rs415430","2011-09-14",21812969,"Liu X","2011-08-03","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21812969","Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.","Parkinson's disease","268 Ashkenazi Jewish cases, 178 Ashkenazi Jewish controls","1,782 European ancestry cases, 1,658 European ancestry controls","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs415430-T","rs415430",0,415430,"intron_variant",0,0.786,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,{"$nulls":3},"Illumina [525124]","N"]
[5,"rs10184054",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.754,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Hispanic)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,0.055,"[0.033-0.077] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[19,"rs2954021",8,126486409,"rs17321515","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-A","rs17321515",0,17321515,"intron_variant",0,0.47,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(LDL)",0.07,"mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[22,"rs538711822",10,65104500,"rs7896518","2018-01-12",29186694,"Lam M","2017-11-28","Cell Rep","www.ncbi.nlm.nih.gov/pubmed/29186694","Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.","Cognitive ability","107,207 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7896518-?","rs7896518",0,7896518,"intron_variant",0,"NR",{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,4.926,"z score decrease","Affymetrix, Illumina [7357080] (imputed)","N"]
[27,"rs7970695",12,121403724,"rs7953249","2017-08-07",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","High-grade serous ovarian cancer","13,037 European ancestry cases, 40,941 European ancestry controls","NA","12q24.31","NR","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.417632,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,1.0811644,"[1.04824881016487-1.11511353852335]","Illumina [11595112] (imputed)","N"]
[32,"rs16940904",17,44865603,"rs199498","2014-10-21",24511991,"Hill-Burns EM","2014-02-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/24511991","Identification of a novel Parkinson's disease locus via stratified genome-wide association study.","Parkinson's disease","1,565 European ancestry sproadic Parkinson's disease cases, 435 European ancestry familial Parkinson's disease cases, 1,986 European ancestry controls","1,528 European ancestry sporadic Parkinson's disease cases, 707 European ancestry familial Parkinson's disease cases, 796 European ancestry controls","17q21.31","MAPT","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199498-T","rs199498",0,199498,"intron_variant",0,0.764,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Familial)",1.69,"[1.57-1.81]","Illumina [811597]","N"]
[18,"rs76722925",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.934,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(AA)",0.225,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs13273454",8,19942181,"rs13263508","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","8p21.3","NR","AC100802.1",null,null,"ENSG00000253775",null,null,"rs13263508-?","rs13263508",0,13263508,"intron_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,0.03603,"[0.022-0.05] unit increase novel","Illumina [6108953] (imputed)","N"]
[35,"rs111503239",19,19719824,"rs10417097","2019-04-29",30255771,"Sarnowski C","2018-09-17","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/30255771","Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels.","Triglyceride levels in response to fenofibrate treatment (parental genotype effect)","173 European ancestry families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs10417097-?","rs10417097",0,10417097,"intron_variant",0,null,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(paternal effect)",null,null,"Affymetrix [715787]","N"]
[38,"rs4818005",21,40663181,"rs2836974","2015-11-08",25644384,"Davies G","2015-02-03","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25644384","Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).","Cognitive function","51,719 European ancestry individuals, 1,473 Erasmus Rucphen (founder/genetic isolate) individuals, 327 Korculan (founder/genetic isolate) individuals, 430 Orcadian (founder/genetic isolate) individuals","NA","21q22.2","BRWD1","BRWD1",null,null,"ENSG00000185658",null,null,"rs2836974-?","rs2836974",0,2836974,"intron_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,0.0281,"[0.017-0.039] unit increase","Affymetrix, Illumina [2478500] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.068,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs952275",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.607,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2015-09-22",25524916,"Palmer ND","2014-12-18","Diabetes","www.ncbi.nlm.nih.gov/pubmed/25524916","Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.","Glucose homeostasis traits","up to 4,176 Mexican American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-?","rs780093",0,780093,"intron_variant",0,null,{"v":1e-06,"d":"1.00E-06"},6,"(SG)",0.14,"[0.081-0.199] unit increase","Illumina [693128]","N"]
[6,"rs4665985",2,27753878,"rs4665985","2017-08-03",28485404,"Jorgenson E","2017-05-09","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28485404","Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.","Alcohol consumption (drinks per week)","23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.          ","NA","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,7327,6375,"rs4665985-C","rs4665985",0,4665985,"intergenic_variant",1,0.28,{"v":1e-06,"d":"1.00E-06"},6,"(EA, adjusted for lean body mass)",0.04,"[0.02-0.05] drinks per week increase","Affymetrix [NR] (imputed)","N"]
[6,"rs1870325",2,28020157,"rs12623170","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","2p23.2","RBKS","RBKS, MRPL33",null,null,"ENSG00000171174, ENSG00000243147",null,null,"rs12623170-C","rs12623170",0,12623170,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(EA)",1.0670081,"[1.04-1.09]","Illumina [6627481] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-C","rs7570971",0,7570971,"intron_variant",0,0.627,{"v":1e-06,"d":"1.00E-06"},6,null,0.016,"[0.0099-0.0229] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[9,"rs10075801",5,131466629,"rs3843503","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","FEV1","321,047 European ancestry individuals","79,005 European ancestry individuals","5q31.1","P4HA2-AS1","RF00285 - AC063976.3","ENSG00000264452","ENSG00000227616",null,50803,16555,"rs3843503-A","rs3843503",0,3843503,"intergenic_variant",1,0.4482,{"v":1e-06,"d":"1.00E-06"},6,null,0.0115,"[0.0068-0.0162] unit decrease","Affymetrix [19819130] (imputed)","N"]
[9,"rs10075801",5,131466629,"rs3843503","2019-03-27",30804560,"Shrine N","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804560","New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.","Lung function (FEV1/FVC)","321,047 European ancestry individuals","79,005 European ancestry individuals","5q31.1","P4HA2-AS1","RF00285 - AC063976.3","ENSG00000264452","ENSG00000227616",null,50803,16555,"rs3843503-A","rs3843503",0,3843503,"intergenic_variant",1,0.4482,{"v":1e-06,"d":"1.00E-06"},6,null,0.0118,"[0.0071-0.0165] unit increase","Affymetrix [19819130] (imputed)","N"]
[11,"rs147662640",6,28073881,"rs34662244","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Urinary tract infection frequency","35,000 European ancestry cases, 33,478 European ancestry controls","NA","6p22.1","NR","ZSCAN12P1 - ZNF602P","ENSG00000219891","ENSG00000219392",null,12439,9525,"rs34662244-?","rs34662244",0,34662244,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.0595,"[0.035-0.084] unit increase","Illumina [at least 560000] (imputed)","N"]
[13,"rs10455872",6,160997118,"rs74617384","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (combined parental age at death)","45,627 middle-aged British individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-?","rs74617384",0,74617384,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.06755,"[0.041-0.095] unit increase","Affymetrix [9658292] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72856269,"rs2240466","2011-05-26",21490707,"Cornelis MC","2011-04-07","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21490707","Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.","Caffeine consumption","47,431 European ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2240466-A","rs2240466",0,2240466,"3_prime_UTR_variant",0,0.12,{"v":1e-06,"d":"1.00E-06"},6,null,0.1109,"[0.07-0.15] mg/day increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[17,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.168,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9185146,"rs2126259","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-A","rs2126259",0,2126259,"intron_variant",0,0.39,{"v":1e-06,"d":"1.00E-06"},6,null,0.11,"[0.071-0.149] unit decrease","Illumina [1361436] (imputed)","N"]
[18,"rs15285",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.463,{"v":1e-06,"d":"1.00E-06"},6,"(AA)",0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.597,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.598,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-06,"d":"1.00E-06"},6,null,0.0395,"[0.024-0.055] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",0.0395,"[0.024-0.055] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[22,"rs538711822",10,64927823,"rs1935","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals","132,177 European ancestry individuals","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs1935-C","rs1935",0,1935,"missense_variant",0,0.5168,{"v":1e-06,"d":"1.00E-06"},6,null,0.011,"[0.0065-0.0155] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[22,"rs538711822",10,65133822,"rs7923609","2015-05-08",25201988,"Rietveld CA","2014-09-08","Proc Natl Acad Sci U S A","www.ncbi.nlm.nih.gov/pubmed/25201988","Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.","Educational attainment","106,736 European ancestry individuals","NA","10q21.3","JMJD1C, REEP3","JMJD1C",null,null,"ENSG00000171988",null,null,"rs7923609-A","rs7923609",0,7923609,"intron_variant",0,0.521,{"v":1e-06,"d":"1.00E-06"},6,null,0.021,"[NR] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[23,"rs4418728",10,94839642,"rs2068888","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-G","rs2068888",0,2068888,"regulatory_region_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.021,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs12791103",11,116665079,"rs9804646","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-C","rs9804646",0,9804646,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.029,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121403724,"rs7953249","2013-01-30",23144326,"Kim DK","2012-11-09","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/23144326","Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.","Chronic obstructive pulmonary disease-related biomarkers","Up to 1,951 European ancestry smokers","NA","12q24.31","TCF1, HNF1A","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.44,{"v":1e-06,"d":"1.00E-06"},6,"(CRP)",null,null,"Illumina [588352]","N"]
[30,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.588,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.588,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261341",15,58738423,"rs12914626","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs12914626-C","rs12914626",0,12914626,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,1.0526316,"[NR]","Illumina [7158791] (imputed)","N"]
[32,"rs16940904",17,44828931,"rs199533","2010-09-22",20711177,"Hamza TH","2010-08-15","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20711177","Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.","Parkinson's disease","2,000 European ancestry cases, 1,986 European ancestry controls","Up to 1,447 cases, 1,468 controls","17q21.31","MAPT","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199533-C","rs199533",0,199533,"synonymous_variant",0,0.78,{"v":1e-06,"d":"1.00E-06"},6,null,1.35,"[1.19-1.52]","Illumina [811597]","N"]
[32,"rs199500",17,44865439,"rs2074404","2010-03-29",20190752,"Dubois PC","2010-02-28","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20190752","Multiple common variants for celiac disease influencing immune gene expression.","Celiac disease","4,533 European ancestry cases, 10,750 European ancestry controls","4,918 European ancestry cases, 5,684 European ancestry controls","17q21.31","intergenic","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs2074404-?","rs2074404",0,2074404,"intron_variant",0,0.75,{"v":1e-06,"d":"1.00E-06"},6,null,1.11,"[1.06-1.16]","Illumina [292387]","N"]
[33,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,0.675,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",0.019,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.986,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.34,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.938,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.139,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2013-04-19",23326517,"Holliday EG","2013-01-11","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23326517","Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.","Age-related macular degeneration","3,772 European ancestry cases, 16,033 European ancestry controls","264 Asian ancestry cases, 3,926 Asian ancestry controls","19q13.32","APOE, PVRL2, TOMM40","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-?","rs6857",0,6857,"3_prime_UTR_variant",0,0.85,{"v":1e-06,"d":"1.00E-06"},6,null,1.23,"[1.14-1.35]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2013-04-19",23326517,"Holliday EG","2013-01-11","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23326517","Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.","Age-related macular degeneration","3,772 European ancestry cases, 16,033 European ancestry controls","264 Asian ancestry cases, 3,926 Asian ancestry controls","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-?","rs6857",0,6857,"3_prime_UTR_variant",0,0.85,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",1.23,"[1.14-1.35]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[36,"rs157580",19,45395266,"rs157580","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(AB1-42)",null,null,"Illumina [322557]","N"]
[36,"rs429358",19,45411941,"rs429358","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(AB1-42, p-tau181p, p-tau181p/AB1-42, t-tau/AB1-42)",null,null,"Illumina [322557]","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.905,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","LOC100129500","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-?","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(AB1-42)",null,null,"Illumina [322557]","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.883,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.897,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index","up to 309,889 European ancestry individuals","NA","19q13.32","APOC1, ZNF229, IGSF23, BCL3, PVRL2, CLPTM1, GEMIN7, EXOC3L2, KLC3, ZNF180, PVR, CBLC, TOMM40, RELB, PPP1R37, MARK4, ERCC1, CEACAM20, MIR4531, BCAM, APOE, CLASRP, BLOC1S3, CKM, CEACAM22P","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.82,{"v":1e-06,"d":"1.00E-06"},6,{"$nulls":3},"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.883,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[39,"rs200991074",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.015,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.655,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.634,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.187,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Asian initial, BMI unadjusted)",0.0494,"[0.029-0.07] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[4,"rs629301",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.933,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.16,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"rs629301",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.069,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2016-12-01",26818947,"Imamura M","2016-01-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26818947","Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.","Type 2 diabetes","15,463 Japanese ancestry cases, 26,183 Japanese ancestry controls","20,490 East Asian ancestry cases, 22,922 East Asian ancestry controls, 38,947 European ancestry cases, 121,903 European ancestry controls, 10,587 South Asian ancestry cases, 14,378 South Asian ancestry controls, 3,848 Mexican/Latino cases, 4,366 Mexican/Latino controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Japanese)",1.0758183,"[1.04425991211509-1.10832920480705]","Illumina [7521072] (imputed)","N"]
[7,"rs11681659",2,135837906,"rs7570971","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","RAB3GAP1","RAB3GAP1",null,null,"ENSG00000115839",null,null,"rs7570971-C","rs7570971",0,7570971,"intron_variant",0,0.64,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA)",0.017,"[0.0098-0.0232] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[7,"rs11681659",2,136092061,"rs1561277","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","2q21.3","ZRANB3","ZRANB3",null,null,"ENSG00000121988",null,null,"rs1561277-A","rs1561277",0,1561277,"intron_variant",0,0.3354,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA,women)",0.0254,"[0.015-0.036] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","MCM6","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.646,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.016,"[0.0094-0.0224] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[9,"rs10075801",5,131770805,"rs2188962","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Ulcerative colitis","12,366 European and unknown ancestry cases, 33,609 European and unknown ancestry controls","NA","5q31.1","IL3, CSF2, HINT1, LYRM7, SLC22A4, C5orf56, IRF1, CDC42SE2, RAPGEF6, ACSL6, P4HA2, PDLIM4, SLC22A5, CTC-432M15.3, FNIP1","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs2188962-?","rs2188962",0,2188962,"intron_variant",0,null,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"Illumina [9578670] (imputed)","N"]
[16,"rs62466318",7,72885810,"rs6976930","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-?","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[16,"rs138574868",7,72987354,"rs2286276","2013-08-01",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","Hypertriglyceridemia","1,122 Mexican ancestry cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry cases, 1,054 Mexican ancestry controls","7q11.23","TBL2, VPS37D, MLXIPL, BAZ1B, BCL7B","TBL2",null,null,"ENSG00000106638",null,null,"rs2286276-?","rs2286276",0,2286276,"non_coding_transcript_exon_variant",0,0.88,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.39,"[1.25-1.53]","Illumina [1361436] (imputed)","N"]
[17,"rs9987289",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.163,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.096,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs9987289",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-G","rs328",0,328,"stop_gained",0,0.092,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,3.7,"[2.19-5.21] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[19,"rs2954021",8,126477978,"rs2001945","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)","95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","8q24.13","TRIB1","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-G","rs2001945",0,2001945,"intergenic_variant",1,0.484,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(women)",null,null,"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.689,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[21,"rs56068105",10,5254847,"rs1832007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10p15.1","NR","AKR1C4",null,null,"ENSG00000198610",null,null,"rs1832007-A","rs1832007",0,1832007,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65027610,"rs10761731","2014-03-25",24026423,"Shameer K","2013-09-12","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/24026423","A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.","Platelet count","13,582 European ancestry individuals","NA","10q21.3","JMJD1C","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10761731-A","rs10761731",0,10761731,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,3.81,"[NR] unit decrease","Illumina [476395]","N"]
[23,"rs4418728",10,94839642,"rs2068888","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q23.33","NR","CYP26A1 - NIP7P1","ENSG00000095596","ENSG00000232805",null,1995,26987,"rs2068888-G","rs2068888",0,2068888,"regulatory_region_variant",1,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.021,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116607437,"rs1558861","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,78469,11449,"rs1558861-T","rs1558861",0,1558861,"regulatory_region_variant",1,0.94,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"[0.02-0.04] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.185,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(South Asian)",0.338,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs12718462",11,117085210,"rs77683187","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs77683187-C","rs77683187",0,77683187,"non_coding_transcript_exon_variant",0,0.0608,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA)",0.0613,"[0.036-0.087] unit increase","Illumina [~ 11800000] (imputed)","N"]
[30,"rs12907378",15,58635583,"rs4775031","2012-11-13",20125193,"Cirulli ET","2010-02-03","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/20125193","Common genetic variation and performance on standardized cognitive tests.","Cognitive performance","Up to 813 European ancestry individuals, up to 167 East Asian ancestry individuals, up to 7 Hispanic/Latin American individuals, up to 74 South Asian ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775031-?","rs4775031",0,4775031,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(TrailsB)",null,null,"Illumina [up to 563855]","N"]
[30,"rs73420594",15,58730639,"rs17301739","2013-06-26",23535033,"Sherva R","2013-03-24","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/23535033","Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.","Alzheimer's disease (cognitive decline)","303 European ancestry cases",null,"15q21.3","LIPC","LIPC-AS1, LIPC, ALDH1A2",null,null,"ENSG00000259293, ENSG00000166035, ENSG00000128918",null,null,"rs17301739-?","rs17301739",0,17301739,"intron_variant",0,0.07,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.28,"unit decrease","Illumina [NR] (imputed)","N"]
[31,"rs72789541",16,15129459,"rs4985155","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.662,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.015,"[0.0089-0.0211] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[31,"rs3198697",16,15129940,"rs3198697","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-C","rs3198697",0,3198697,"missense_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.017,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs16940904",17,44865603,"rs199498","2014-10-21",24511991,"Hill-Burns EM","2014-02-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/24511991","Identification of a novel Parkinson's disease locus via stratified genome-wide association study.","Parkinson's disease","1,565 European ancestry sproadic Parkinson's disease cases, 435 European ancestry familial Parkinson's disease cases, 1,986 European ancestry controls","1,528 European ancestry sporadic Parkinson's disease cases, 707 European ancestry familial Parkinson's disease cases, 796 European ancestry controls","17q21.31","MAPT","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199498-T","rs199498",0,199498,"intron_variant",0,0.764,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.35,"[1.25-1.45]","Illumina [811597]","N"]
[33,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.137,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.017,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs3883367",18,47328029,"rs617619","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","18q21.1","NR","ACAA2, AC090227.1",null,null,"ENSG00000167315, ENSG00000266997",null,null,"rs617619-?","rs617619",0,617619,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"Affymetrix [NR]","N"]
[34,"rs142158911",19,11202306,"rs6511720","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.083,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,3.75,"[2.20-5.30] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.881,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.0165,"[0.0096-0.0234] unit increase","Affymetrix [11535925] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.986,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.33,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11202306,"rs6511720","2019-04-30",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Total cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Indian)",null,null,"Illumina [551825]","N"]
[36,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.789,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(AA)",0.151,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.543,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","19q13.32","APOC2, APOE, APOC4, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.21,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(CRP)",0.28,"[NR] mg/L decrease","Affymetrix [408775]","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.371,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.067,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2017-03-31",27702941,"Cornelis MC","2016-10-03","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/27702941","Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.","Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio)","5,323 European ancestry individuals","824 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,4.69,"Z-score decrease","Illumina [~ 31000000] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Palmitic acid (16:0) levels","8,961 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1261,"unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs202049562",2,27789861,"rs965813","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","AC109829.1","C2orf16",null,null,"ENSG00000221843",null,null,"rs965813-A","rs965813",0,965813,"missense_variant",0,0.333,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0415,"[0.024-0.059] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[11,"rs147662640",6,29153155,"rs3130746","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tuberculosis","4,426 European ancestry cases, 84,290 European ancestry controls","NA","6p22.1","NR","OR2J4P - AL645937.3","ENSG00000218297","ENSG00000230598",null,2933,27508,"rs3130746-?","rs3130746",0,3130746,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1783,"[0.1-0.25] unit increase","Illumina [at least 560000] (imputed)","N"]
[16,"rs71553242",7,72129667,"rs13238203","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.22","TYW1B","TYW1B",null,null,"ENSG00000277149",null,null,"rs13238203-T","rs13238203",0,13238203,"intron_variant",0,0.04,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.059,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[16,"7:73042302_GCTTT_G",7,72864869,"rs714052","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-?","rs714052",0,714052,"intron_variant",0,0.87,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,2.27,"[1.61-3.23]","Affymetrix [~ 2100000] (imputed)","N"]
[16,"rs62466318",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0351,"[0.02-0.05] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[16,"rs62466318",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.905,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.902,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.05,"[1.03-1.08]","Affymetrix, Illumina [247470]","N"]
[18,"rs76722925",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.902,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.05,"[1.03-1.07]","Affymetrix, Illumina [247470]","N"]
[18,"rs76722925",8,19833156,"rs80073370","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Pulse pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8p21.3","LPL, SLC18A1","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,8386,103469,"rs80073370-A","rs80073370",0,80073370,"regulatory_region_variant",1,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.219,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[19,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.045,"[0.025-0.065] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.551395,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.04,"[1.03- 1.06]","Affymetrix, Illumina [8600000] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs35309034",8,126498828,"rs4870941","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-?","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(male)",0.1938,"[0.11-0.28] unit decrease","Affymetrix [7794483] (imputed)","N"]
[19,"rs35309034",8,126504726,"rs6987702","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6987702-G","rs6987702",0,6987702,"intron_variant",0,0.29,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[22,"rs538711822",10,65318766,"rs10761785","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","10q21.3","REEP3","REEP3",null,null,"ENSG00000165476",null,null,"rs10761785-G","rs10761785",0,10761785,"intron_variant",0,0.486,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.019,"[0.011-0.026] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[26,"rs2266788",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.187,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(South Asian)",0.332,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs12718462",11,116936871,"rs56751865","2018-01-29",29198719,"Shaffer JR","2017-11-30","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29198719","Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment.","Lobe attachment (rater scored)","1791 European ancestry individuals, 5,062 Hispanic individuals, 2,857 Han Chinese ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs56751865-?","rs56751865",0,56751865,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Chinese)",0.1026,"[0.06-0.146] unit decrease","Illumina [at least 7383741] (imputed)","N"]
[26,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.028,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,43820717,"rs55707100","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","MAP1A",null,null,"ENSG00000166963",null,null,"rs55707100-C","rs55707100",0,55707100,"missense_variant",0,0.973,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.204,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1561458",15,44262875,"rs2623015","2018-07-23",29698431,"Roosenboom J","2018-04-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29698431","Mapping genetic variants for cranial vault shape in humans.","Cephalic index","4,419 European ancestry individuals","NA","15q15.3","NR","FRMD5",null,null,"ENSG00000171877",null,null,"rs2623015-C","rs2623015",0,2623015,"intron_variant",0,0.04709,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.6957,"[0.22-1.17] unit increase","Illumina [at least 567677] (imputed)","N"]
[30,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.888,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.64,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.612,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs60315394",15,58712203,"rs11857380","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs11857380-C","rs11857380",0,11857380,"5_prime_UTR_variant",0,0.131,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Weight )",0.03,"[NR] kg increase","Illumina [899892]","N"]
[30,"rs1077835",15,58723675,"rs1800588","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.41,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.078,"[0.045-0.111] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[31,"rs56213767",16,15379572,"rs56213767","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (mother's age at death)","52,776 middle-aged British individuals","NA","16p13.11","NR","AC126763.1 - AC137803.1","ENSG00000257391","ENSG00000277770",null,128695,73263,"rs56213767-?","rs56213767",0,56213767,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.028136,"[0.016-0.04] unit increase","Affymetrix [9658292] (imputed)","N"]
[31,"rs1684546",16,15587497,"rs34792","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","16p13.11","C16orf45","C16orf45, C16orf45, AC140504.1",null,null,"ENSG00000278823, ENSG00000166780, ENSG00000261130",null,null,"rs34792-C","rs34792",0,34792,"intron_variant",0,0.38,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.21,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs16940904",17,44819565,"rs199443","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199443-T","rs199443",0,199443,"intron_variant",0,0.2,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Ajusted for ApoE)",0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[35,"rs11882123",19,19552413,"rs4808955","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808955-?","rs4808955",0,4808955,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0401,"[0.023-0.057] unit decrease","Illumina [at least 560000] (imputed)","N"]
[35,"rs7245672",19,19692579,"rs7252981","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Perceived unattractiveness to mosquitoes","16,576 European ancestry individuals","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs7252981-T","rs7252981",0,7252981,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.112447,"[0.065-0.16] unit decrease","Illumina [7433384] (imputed)","N"]
[35,"rs111503239",19,19719824,"rs10417097","2019-04-29",30255771,"Sarnowski C","2018-09-17","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/30255771","Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels.","Triglyceride levels in response to fenofibrate treatment (parental genotype effect)","173 European ancestry families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs10417097-?","rs10417097",0,10417097,"intron_variant",0,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(paternal & maternal alleles modelled separately)",null,null,"Affymetrix [715787]","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.12,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.02,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.897,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs6129624",20,39154095,"rs6016373","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,399098,160393,"rs6016373-A","rs6016373",0,6016373,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.018,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs1167998",1,63049593,"rs1748195","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Crohn's disease","12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls","NA","1p31.3","ANGPTL3, AL138847.1, DOCK7, USP1","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-?","rs1748195",0,1748195,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [9560910] (imputed)","N"]
[4,"rs629301",1,109818530,"rs646776","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.19,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(chol, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[5,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum total protein level","Up to 25,539 European ancestry individuals, 10,168 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.56,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Japanese)",0.031,"[0.017-0.045] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs200800380",5,131721204,"rs274557","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","8,631 European ancestry individuals","NA","5q31.1","SLC22A5","SLC22A5",null,null,"ENSG00000197375",null,null,"rs274557-T","rs274557",0,274557,"intron_variant",0,0.599,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.14,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[20,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.778,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Asian initial, BMI unadjusted)",0.0449,"[0.026-0.064] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","Metabolic syndrome","1,811 Taiwanese Han Chinese ancestry cases, 8,489 Taiwanese Han Chinese ancestry controls","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(additive)",1.25,"[1.14-1.37]","Affymetrix [583469]","N"]
[26,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.023,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs690170",15,43784475,"rs2439831","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","15q15.3","TP53BP1","TP53BP1",null,null,"ENSG00000067369",null,null,"rs2439831-C","rs2439831",0,2439831,"splice_region_variant",0,0.891060495,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,1.1158895,"[1.07-1.17]","Illumina [10439017] (imputed)","N"]
[30,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.33,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.628,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.104,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.52,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs3198697",16,15129940,"rs3198697","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16p13.11","NR","PDXDC1",null,null,"ENSG00000179889",null,null,"rs3198697-C","rs3198697",0,3198697,"missense_variant",0,0.585,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.018,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15138413,"rs3803573","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","16p13.11","NR","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs3803573-?","rs3803573",0,3803573,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(female)",0.12148,"[0.07-0.173] unit decrease","Affymetrix [7794483] (imputed)","N"]
[31,"rs79295535",16,15883490,"rs17214007","2015-11-08",25644384,"Davies G","2015-02-03","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25644384","Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).","Cognitive function","51,719 European ancestry individuals, 1,473 Erasmus Rucphen (founder/genetic isolate) individuals, 327 Korculan (founder/genetic isolate) individuals, 430 Orcadian (founder/genetic isolate) individuals","NA","16p13.11","MYH11","MYH11, MYH11",null,null,"ENSG00000133392, ENSG00000276480",null,null,"rs17214007-?","rs17214007",0,17214007,"intron_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0356,"[0.021-0.051] unit decrease","Affymetrix, Illumina [2478500] (imputed)","N"]
[32,"rs16940904",17,44819565,"rs199443","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","NSF","NSF, NSF, NSF",null,null,"ENSG00000278174, ENSG00000276262, ENSG00000073969",null,null,"rs199443-T","rs199443",0,199443,"intron_variant",0,0.2,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[32,"rs199500",17,44863133,"rs916888","2017-03-20",27629089,"Sailer A","2016-09-14","Neurology","www.ncbi.nlm.nih.gov/pubmed/27629089","A genome-wide association study in multiple system atrophy.","Multiple system atrophy","918 European ancestry cases, 3,864 European ancestry controls","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs916888-T","rs916888",0,916888,"intron_variant",0,0.75,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,1.35,null,"Illumina [4903804] (imputed)","N"]
[33,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,0.675,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.31,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.308,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58542926",19,19721722,"rs12610185","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs12610185-A","rs12610185",0,12610185,"intron_variant",0,0.053,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(TG )",0.03,"[NR] mg/dL increase","Illumina [899892]","N"]
[36,"rs9304644",19,45449199,"rs2288912","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","19q13.32","APOC2, CLPTM1, APOE, APOC4","APOC4-APOC2",null,null,"ENSG00000224916",null,null,"rs2288912-C","rs2288912",0,2288912,"3_prime_UTR_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,4.617,"[NR] Z score increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(mass)",5.3E-3,"[-0.00215-0.01275] ng/ml decrease","Illumina [796174]","N"]
[6,"rs1260326",2,27730940,"rs1260326","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.012,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Urate levels","8,868 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.57,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.069,"[0.040,0.098] unit increase","Illumina [561583]","N"]
[6,"rs1260326",2,27742603,"rs780093","2012-08-20",22747683,"Eriksson N","2012-06-30","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/22747683","Genetic variants associated with breast size also influence breast cancer risk.","Breast size","16,175 European ancestry female individuals","NA","2p23.3","SLC4A1AP","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.416,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.072,"[0.041-0.103] cup size increase","Illumina [7422970] (imputed)","N"]
[7,"rs11681659",2,136608646,"rs4988235","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","2q21.3","MCM6","MCM6",null,null,"ENSG00000076003",null,null,"rs4988235-A","rs4988235",0,4988235,"intron_variant",0,0.66,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.016,"[0.0091-0.0225] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[11,"rs147662640",6,28482917,"rs13191038","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Urinary tract infection frequency","35,000 European ancestry cases, 33,478 European ancestry controls","NA","6p22.1","NR","GPX6, GPX6",null,null,"ENSG00000281185, ENSG00000198704",null,null,"rs13191038-?","rs13191038",0,13191038,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.058,"[0.033-0.083] unit increase","Illumina [at least 560000] (imputed)","N"]
[18,"rs15285",8,19865175,"rs2083637","2008-06-22",18454146,"Chambers JC","2008-05-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18454146","Common genetic variation near MC4R is associated with waist circumference and insulin resistance.","Waist circumference and related phenotypes","2,684 Indian Asian ancestry male individuals","7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,40405,71450,"rs2083637-?","rs2083637",0,2083637,"regulatory_region_variant",1,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(HDL cholesterol)",null,null,"Illumina [308067]","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA, women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[20,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[25,"rs673335",11,75455309,"rs600626","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)","8,631 European ancestry individuals","NA","11q13.5","MOGAT2","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1838,14191,"rs600626-A","rs600626",0,600626,"regulatory_region_variant",1,0.827,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.07,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,4.581,"[NR] Z score increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","11q23.3","ZNF259, APOA5, APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.163,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.05,"[1.03-1.08]","Affymetrix [9149595] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.191,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(South Asian)",0.333,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs28364531",15,42683787,"rs2412710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.1","NR","AC012651.1, CAPN3",null,null,"ENSG00000258461, ENSG00000092529",null,null,"rs2412710-G","rs2412710",0,2412710,"intron_variant",0,0.969,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.181,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs139974673",15,43726625,"rs150844304","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.3","NR","TP53BP1",null,null,"ENSG00000067369",null,null,"rs150844304-A","rs150844304",0,150844304,"intron_variant",0,0.974,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.198,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.596,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15129459,"rs4985155","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","16p13.11","PDXDC1","PDXDC1",null,null,"ENSG00000179889",null,null,"rs4985155-A","rs4985155",0,4985155,"intron_variant",0,0.664,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.015,"[0.0084-0.0214] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[32,"rs16940904",17,43824360,"rs7207400","2016-02-03",25778476,"Jun G","2015-03-17","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25778476","A novel Alzheimer disease locus located near the gene encoding tau protein.","Alzheimer's disease in APOE e4- carriers","7,184 cases, 26,968 controls","718 European ancestry cases, 1,699 European ancestry controls","17q21.31","CRHR1","LINC02210-CRHR1, LINC02210-CRHR1",null,null,"ENSG00000263715, ENSG00000282456",null,null,"rs7207400-T","rs7207400",0,7207400,"intron_variant",0,0.75,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.1363636,"[1.08-1.2]","NR [NR]","N"]
[32,"rs199500",17,44863133,"rs916888","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs916888-T","rs916888",0,916888,"intron_variant",0,0.763,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.051,"NR unit increase","Illumina [NR] (imputed)","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.914,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.027,"[0.015-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[36,"rs429358",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.883,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","19q13.32","APOC2, APOE, APOC4, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.21,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(TG)",0.22,"[NR] mg/dL increase","Affymetrix [408775]","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.883,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.065,"[0.038-0.092] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[6,"rs1260326",2,27741237,"rs780094","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.59,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.05,"[0.028-0.072] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[6,"rs11691385",2,28320033,"rs7572644","2016-12-11",27047539,"Fridley BL","2016-03-22","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27047539","Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence.","Response to carboplatin and paclitaxel in ovarian cancer (Caspase 3/7 EC50)","74 lymphoblastoid cell lines","NA","2p23.2","BRE","BABAM2",null,null,"ENSG00000158019",null,null,"rs7572644-?","rs7572644",0,7572644,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,{"$nulls":3},"Illumina [6243550] (imputed)","N"]
[20,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7084630",10,5239824,"rs7087111","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10p15.1","NR","AKR1C4",null,null,"ENSG00000198610",null,null,"rs7087111-C","rs7087111",0,7087111,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121403724,"rs7953249","2017-08-03",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Invasive epithelial ovarian cancer","22,406 European ancestry cases, 40,941 European ancestry controls","NA","12q24.31","NR","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.417632,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.0621586,"[1.0348111352015-1.09022867520121]","Illumina [11595112] (imputed)","N"]
[31,"rs72789541",16,15138413,"rs3803573","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","16p13.11","NR","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs3803573-?","rs3803573",0,3803573,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(male)",0.17267,"[0.098-0.247] unit decrease","Affymetrix [7794483] (imputed)","N"]
[32,"rs16940904",17,44865498,"rs199499","2016-02-03",25778476,"Jun G","2015-03-17","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25778476","A novel Alzheimer disease locus located near the gene encoding tau protein.","Alzheimer's disease in APOE e4- carriers","7,184 cases, 26,968 controls","718 European ancestry cases, 1,699 European ancestry controls","17q21.31","WNT3","WNT3, WNT3",null,null,"ENSG00000108379, ENSG00000277641",null,null,"rs199499-C","rs199499",0,199499,"intron_variant",0,0.81,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.1627907,"[1.09-1.23]","NR [NR]","N"]
[35,"rs61061000",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Systolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.34,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Japanese)",0.3725,"[0.21-0.53] unit increase","Illumina [6200000] (imputed)","N"]
[36,"rs157595",19,45425460,"rs157595","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19q13.32","APOC1, APOC1P1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-A","rs157595",0,157595,"intergenic_variant",1,0.397,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.032,"[0.018-0.046] unit decrease","Affymetrix [7947838] (imputed)","N"]
[4,"rs629301",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.078,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.134,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs1260326",2,27742603,"rs780093","2010-09-21",20705733,"O'Seaghdha CM","2010-08-12","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20705733","Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.","Calcium levels","20,611 European ancestry individuals","NA","2p23.3","FNDC4, IFT172, GCKR, C2orf16","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[6,"rs77200710",2,27801759,"rs1919128","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919128-G","rs1919128",0,1919128,"missense_variant",0,0.529,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0379,"[0.021-0.054] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[11,"rs147662640",6,28796071,"rs3131337","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Cold sores","25,108 European ancestry cases, 63,332 European ancestry controls","NA","6p22.1","NR","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,44290,9575,"rs3131337-?","rs3131337",0,3131337,"regulatory_region_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0811,"[0.046-0.116] unit decrease","Illumina [at least 560000] (imputed)","N"]
[11,"rs147662640",6,28916594,"rs3130844","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Urinary tract infection frequency","35,000 European ancestry cases, 33,478 European ancestry controls","NA","6p22.1","NR","LINC01556 - KRT18P1","ENSG00000231041","ENSG00000226462",null,4280,20313,"rs3130844-?","rs3130844",0,3130844,"regulatory_region_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0564,"[0.032-0.081] unit increase","Illumina [at least 560000] (imputed)","N"]
[13,"rs10455872",6,161108144,"rs2315065","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (combined parental age at death)","45,627 middle-aged British individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,10589,11176,"rs2315065-?","rs2315065",0,2315065,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.056891,"[0.032-0.082] unit increase","Affymetrix [9658292] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.614,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs33924196",8,126507389,"rs2954038","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","8q24.13","NSMCE2, KIAA0196, TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-C","rs2954038",0,2954038,"intron_variant",0,0.32,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Triglyceride, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[26,"11:116837730_AG_A",11,116921397,"rs1815787","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs1815787-T","rs1815787",0,1815787,"intron_variant",0,0.1173,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.020935446,"[0.012-0.03] unit increase","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[29,"rs28364531",15,42683787,"rs2412710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q15.1","NR","AC012651.1, CAPN3",null,null,"ENSG00000258461, ENSG00000092529",null,null,"rs2412710-G","rs2412710",0,2412710,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.054,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.376,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.057,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.815,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs72789541",16,15131974,"rs1136001","2010-03-25",20189936,"Okada Y","2010-02-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20189936","A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.","Height","19,633 Japanese ancestry individuals","NA","16p13.11","PDXDC1, NTAN1","NTAN1, PDXDC1",null,null,"ENSG00000157045, ENSG00000179889",null,null,"rs1136001-T","rs1136001",0,1136001,"missense_variant",0,0.44,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.05,"[0.03-0.07] cm decrease","Illumina [420885]","N"]
[32,"17:43511281_TGGCTAACACGGTGAAACCCC_T",17,43567337,"rs1879586","2017-08-03",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Ovarian cancer in BRCA1 mutation carriers","2,933 European ancestry carrier cases, 16,103 European ancestry carrier controls","NA","17q21.31","NR","PLEKHM1, PLEKHM1, PLEKHM1",null,null,"ENSG00000276358, ENSG00000225190, ENSG00000277111",null,null,"rs1879586-G","rs1879586",0,1879586,"intron_variant",0,0.181254,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,1.1804551,"[1.0983093028467-1.26874471717965]","Illumina [11595112] (imputed)","N"]
[32,"rs199460",17,44364209,"rs2732614","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","KIAA1267, LRRC37","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2732614-T","rs2732614",0,2732614,"intron_variant",0,0.2,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Ajusted for ApoE)",0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[33,"rs17798991",18,47121316,"rs17798991","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs17798991-A","rs17798991",0,17798991,"3_prime_UTR_variant",0,0.387,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Light activity )",0.03,"[NR] %awake time increase","Illumina [899892]","N"]
[33,"rs9964067",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs111503239",19,19719824,"rs10417097","2019-04-29",30255771,"Sarnowski C","2018-09-17","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/30255771","Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels.","Triglyceride levels in response to fenofibrate treatment (parental genotype effect)","173 European ancestry families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs10417097-?","rs10417097",0,10417097,"intron_variant",0,null,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(difference between paternal and maternal transmissions)",null,null,"Affymetrix [715787]","N"]
[3,"rs1167998",1,63118196,"rs10889353","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.32,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.06,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[5,"rs668948",2,21294975,"rs541041","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","2p24.1","FLJ21820, GDF7, APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.16,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(LDL, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[6,"rs74630263",2,27642734,"rs11675428","2018-11-13",25604533,"Renauer PA","2015-01-20","Arthritis Rheumatol","www.ncbi.nlm.nih.gov/pubmed/25604533","Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.","Takayasu arteritis","516 Turkish ancestry cases, 119 European ancestry cases, 462 Turkish ancestry controls, 993 European ancestry controls","NA","2p23.3","PPM1G, NRBP1","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,10180,7923,"rs11675428-?","rs11675428",0,11675428,"intergenic_variant",1,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.8518518,"[NR]","Illumina [up to 547389]","N"]
[9,"rs10075801",5,131784393,"rs12521868","2017-09-22",28739976,"Wain LV","2017-07-24","Hypertension","www.ncbi.nlm.nih.gov/pubmed/28739976","Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.","Diastolic blood pressure","150,134 European ancestry individuals","87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals","5q31.1","c5orf56","AC116366.3, C5orf56",null,null,"ENSG00000283782, ENSG00000197536",null,null,"rs12521868-T","rs12521868",0,12521868,"intron_variant",0,0.405,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA, initial)",0.199,"[0.11-0.29] unit decrease","Affymetrix, Illumina, Perlegen [7994604] (imputed)","N"]
[17,"rs9987289",8,9184231,"rs4240624","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-G","rs4240624",0,4240624,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.0869565,"[NR]","Illumina [7158791] (imputed)","N"]
[18,"rs15285",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.501,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(AA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs15285",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.505,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(AA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.502,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs112875651",8,126506694,"rs112875651","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8q24.13","TRIB1, LOC100130231","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.11,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[21,"rs56068105",10,5254847,"rs1832007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10p15.1","NR","AKR1C4",null,null,"ENSG00000198610",null,null,"rs1832007-A","rs1832007",0,1832007,"intron_variant",0,0.852,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs538711822",10,65271488,"rs10740131","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma levels","7,701 Finnish ancestry individuals","NA","10q21.3","NR","JMJD1C",null,null,"ENSG00000171988",null,null,"rs10740131-T","rs10740131",0,10740131,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.0727,"[0.041-0.104] SD units increase","NR [10700000] (imputed)","N"]
[26,"rs56224630",11,116613660,"rs12280753","2010-09-28",20838585,"Smith EN","2010-09-09","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20838585","Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.","Cardiovascular risk factors (age interaction)","525 European ancestry individuals","2,442 Finnish ancestry individuals","11q23.3","CADM1, APOA5, BUD13","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,84692,5226,"rs12280753-T","rs12280753",0,12280753,"regulatory_region_variant",1,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(triglycerides)",0.69,"[0.40-0.98] unit increase","Illumina [2173391] (imputed)","N"]
[30,"rs261290",15,58683366,"rs1532085","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.403,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(Filipino)",1.634,"[1.56-1.70] unit decrease","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[30,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.358,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs199460",17,44364209,"rs2732614","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","17q21.31","KIAA1267, LRRC37","ARL17B, ARL17B, ARL17B",null,null,"ENSG00000275748, ENSG00000276276, ENSG00000228696",null,null,"rs2732614-T","rs2732614",0,2732614,"intron_variant",0,0.2,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.03,"[0.01-0.05] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[34,"rs737338",19,11330942,"rs17699030","2012-11-02",20889312,"Wang KS","2010-10-01","Schizophr Res","www.ncbi.nlm.nih.gov/pubmed/20889312","A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.","Bipolar disorder and schizophrenia","651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs17699030-?","rs17699030",0,17699030,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7062,"[NR]","Affymetrix [722112]","N"]
[35,"rs111503239",19,19719824,"rs10417097","2019-04-29",30255771,"Sarnowski C","2018-09-17","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/30255771","Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels.","Triglyceride levels (parental genotype effect)","173 European ancestry families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs10417097-?","rs10417097",0,10417097,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(paternal effect)",null,null,"Affymetrix [715787]","N"]
[35,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs429358",19,45392254,"rs6857","2016-04-28",26154020,"Ferrari R","2015-06-12","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/26154020","A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.","Frontotemporal dementia","530 European ancestry cases, 926 European ancestry controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.13,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7,"[1.46-1.94]","Illumina [2292247] (imputed)","N"]
[2,"rs11591147",1,55505647,"rs11591147","2018-05-11",29436472,"Casalone E","2018-02-07","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/29436472","A novel variant in GLIS3 is associated with osteoarthritis.","Osteoarthritis of the knee (with total joint replacement)","2,188 European ancestry cases, 9,939 European ancestry healthy controls","2,281 European ancestry cases, 9,194 European ancestry healthy controls","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.017137,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,1.56,"[1.25-1.95]","Illumina [270934]","N"]
[3,"rs1167998",1,62912919,"rs10158897","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","1p31.3","USP1","USP1",null,null,"ENSG00000162607",null,null,"rs10158897-T","rs10158897",0,10158897,"intron_variant",0,0.2,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(LDL)",0.021,"mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[5,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.021,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs201353310",2,27801418,"rs1919126","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919126-C","rs1919126",0,1919126,"missense_variant",0,null,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.20432469,"[0.11-0.29] unit decrease","Illumina [247039]","N"]
[17,"rs9987289",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs76722925",8,19844222,"rs12678919","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.18,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(HDL)",0.125,"[0.070-0.180] unit increase","Illumina [561583]","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2266788",11,116647607,"rs2160669","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs2160669-G","rs2160669",0,2160669,"3_prime_UTR_variant",0,0.168,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(TG/HDLC )",0.03,"[NR] mmol/L increase","Illumina [899892]","N"]
[26,"rs2266788",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.115,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(Hispanic)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs60811331",19,19276359,"rs7249142","2013-06-14",23382691,"Lauc G","2013-01-31","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23382691","Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.","IgG glycosylation","2,247 European ancestry individuals","NA","19p13.11","NR","MEF2B, BORCS8-MEF2B",null,null,"ENSG00000213999, ENSG00000064489",null,null,"rs7249142-G","rs7249142",0,7249142,"intron_variant",0,0.619273395452519,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(IGP30)",0.1523,"[0.085-0.219] unit increase","Illumina [~ 2500000] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.883,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs7970695",12,121423659,"rs9738226","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs9738226-A","rs9738226",0,9738226,"intron_variant",0,0.39,"1E-313",313,"(BMI-adjusted)",0.148,"[0.14-0.16] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[13,"rs10455872",6,160985526,"rs118039278","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs118039278-A","rs118039278",0,118039278,"intron_variant",0,null,"1E-396",396,null,32.43,"[31.14-33.72] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[26,"rs964184",11,116648917,"rs964184","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8418,"1E-500",500,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[26,"rs2266788",11,116662579,"rs651821","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-?","rs651821",0,651821,"5_prime_UTR_variant",0,"NR","1E-537",537,null,0.2208,"[0.21-0.23] unit decrease novel","Illumina [6108953] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,"3E-418",417.52287874528,"(Leucine-rich repeat neuronal protein 1, LRRN1.11293.14.3)",1.18,"[1.12-1.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs2266788",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.92,"4E-315",314.397940008672,"(Trans-ethnic initial)",0.247,"[0.23-0.26] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,"4E-328",327.397940008672,null,0.247,"[0.24-0.26] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,"5E-646",645.301029995664,"(Tubulin-specific chaperone A, TBCA.12501.10.3)",1.34,"[1.3-1.38] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45411941,"rs429358","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,"6E-363",362.221848749616,"(BMI-adjusted)",0.24,"[0.23-0.25] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[36,"rs190921611",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,"7E-370",369.154901959985,"(Valine--tRNA ligase, VARS.13083.18.3)",0.87,"[0.83-0.91] unit increase","Affymetrix [10572788] (imputed)","N"]
[36,"rs429358",19,45416741,"rs438811","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.232,"9E-875",874.04575749056,"(Protein S100-A13, S100A13.7223.60.3)",1.24,"[1.2-1.28] unit decrease","Affymetrix [10572788] (imputed)","N"]

{"sheet":"ST6C","index":14,"n_rows":5521,"n_cols":37,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["GenomicLocus","IndSigSNP","chr","bp","snp","DateAddedToCatalog","PMID","FirstAuth","Date","Journal","Link","Study","Trait","InitialN","ReplicationN","Region","ReportedGene","MappedGene","UpGene","DownGene","SNP_Gene_ID","UpGeneDist","DownGeneDist","Strongest","SNPs","marged","SNP_ID_cur","Context","intergenic","RiskAF","P","Pmlog","Ptext","OrBeta","95CI","Platform","CNV"]
[5,"rs3832016",1,109817192,"rs7528419","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7782,{"v":0,"d":"0.00E+00"},308.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs3816117",16,56996211,"rs711752","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs711752-A","rs711752",0,711752,"splice_region_variant",0,"NR",{"v":4e-308,"d":"4.00E-308"},307.397940008672,{"$nulls":3},"NR [2501543] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":1E-305,"d":"1.00E-305"},305,null,0.229,"[0.22-0.24] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[30,"rs174564",11,61623140,"rs174601","2015-07-27",25500335,"Tintle NL","2014-12-02","Prostaglandins Leukot Essent Fatty Acids","www.ncbi.nlm.nih.gov/pubmed/25500335","A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study.","Red blood cell fatty acid levels","2,633 individuals","NA","11q12.2","C11orf9, C11orf10, FEN1, FADS1, FADS2, RAB3IL1, DAGLA, BEST1","FADS2",null,null,"ENSG00000134824",null,null,"rs174601-?","rs174601",0,174601,"non_coding_transcript_exon_variant",0,0.35,{"v":3e-305,"d":"3.00E-305"},304.52287874528,"(DGLA)",0.591,"[NR] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1e-302,"d":"1.00E-302"},302,"(BIRC2)",1.6999545,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs611917",1,109815252,"rs611917","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs611917-A","rs611917",0,611917,"non_coding_transcript_exon_variant",0,0.6818,{"v":1E-300,"d":"1.00E-300"},300,null,0.1122,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7715,{"v":1E-300,"d":"1.00E-300"},300,null,0.1364,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.379,{"v":1E-300,"d":"1.00E-300"},300,null,0.1118,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19830170,"rs1569209","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,5400,106455,"rs1569209-T","rs1569209",0,1569209,"regulatory_region_variant",1,0.9206,{"v":1E-300,"d":"1.00E-300"},300,null,0.2112,"[0.2-0.22] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs651821",11,116586283,"rs7350481","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-T","rs7350481",0,7350481,"regulatory_region_variant",1,0.0708,{"v":1E-300,"d":"1.00E-300"},300,null,0.2272,"[0.22-0.24] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.251,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.25,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs58065809",11,117002403,"rs6589598","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","PCSK7","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,12506,3841,"rs6589598-G","rs6589598",0,6589598,"intergenic_variant",1,0.778,{"v":1E-300,"d":"1.00E-300"},300,"(PCSK7)",1.043,"[1-1.09] unit increase","Illumina [> 1000000] (imputed)","N"]
[33,"rs35350651",12,111833788,"rs10774624","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","12q24.12",null,"LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-?","rs10774624",0,10774624,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.685,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.216,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.213,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.208,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.219,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.683,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.218,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.212,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993886,"rs821840","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.6902,{"v":1E-300,"d":"1.00E-300"},300,null,0.2211,"[0.22-0.23] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs247617",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.716,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.218,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.685,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.212,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.822,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.217,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.207,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.564,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.821,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11187324,"rs143020224","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs143020224-C","rs143020224",0,143020224,"intron_variant",0,0.8693,{"v":1E-300,"d":"1.00E-300"},300,null,0.1619,"[0.15-0.17] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[46,"rs41290120",19,45319631,"rs118147862","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","BCAM","BCAM",null,null,"ENSG00000187244",null,null,"rs118147862-A","rs118147862",0,118147862,"intron_variant",0,0.0369,{"v":1E-300,"d":"1.00E-300"},300,null,0.3977,"[0.38-0.41] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.493,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.498,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.342,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.348,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","HERPUD1, CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-?","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":2e-300,"d":"2.00E-300"},299.698970004336,null,0.2656,"[0.25-0.28] unit increase novel","Illumina [6108953] (imputed)","N"]
[34,"rs7970695",12,121424861,"rs7310409","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.39,{"v":3e-299,"d":"3.00E-299"},298.52287874528,null,0.137,"[0.13-0.14] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-297,"d":"3.00E-297"},296.52287874528,null,0.14,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2010-06-14",20460622,"Seshadri S","2010-05-12","JAMA","www.ncbi.nlm.nih.gov/pubmed/20460622","Genome-wide analysis of genetic loci associated with Alzheimer disease.","Alzheimer's disease","973 incident AD cases, 2,033 prevalent AD cases, 22,604  controls of European and Hispanic ancestry","6,505 European ancestry cases, 13,532 European ancestry controls","19q13.32","APOE","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,0.14,{"v":1e-295,"d":"1.00E-295"},295,null,2.53,"[2.41-2.66]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs75627662",19,45413576,"rs75627662","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Family history of Alzheimer's disease","47,793 European ancestry cases, 328,320 European ancestry controls","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-T","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-295,"d":"1.00E-295"},295,null,36.79,"NR z-score increase","Affymetrix [10847151] (imputed)","N"]
[22,"rs7816447",8,19850099,"rs79407615","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,25329,86526,"rs79407615-T","rs79407615",0,79407615,"intergenic_variant",1,0.9025,{"v":3e-293,"d":"3.00E-293"},292.52287874528,null,0.1799,"[0.17-0.19] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":4E-289,"d":"4.00E-289"},288.397940008672,"(Trans-ethnic initial)",0.16,"[0.15-0.17] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":6e-289,"d":"6.00E-289"},288.221848749616,null,0.247,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":7E-287,"d":"7.00E-287"},286.154901959985,null,0.246,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19q13.32","APOC1, APOE, APOC2","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.066,{"v":2e-286,"d":"2.00E-286"},285.698970004336,"(Trans-ethnic initial)",0.59,"[0.57-0.61] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[18,"rs56393506",6,161089307,"rs56393506","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,null,{"v":8e-285,"d":"8.00E-285"},284.096910013008,null,13.6,"[12.78-14.42] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":6e-284,"d":"6.00E-284"},283.221848749616,null,0.239,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-283,"d":"1.00E-283"},283,{"$nulls":3},"NR [2501749] (imputed)","N"]
[43,"rs142158911",19,11196886,"rs8106503","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,6784,3152,"rs8106503-T","rs8106503",0,8106503,"intergenic_variant",1,0.8354,{"v":2E-281,"d":"2.00E-281"},280.698970004336,null,0.1334,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","11q12.2","FTH1, INCENP, FADS1, FADS2, SCGB1D1, SCGB2A1, C11orf9, DAGLA, FEN1, RAB3IL, C11orf10, FADS3, SYT7, BEST1, SCGB1D2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.676,{"v":4e-274,"d":"4.00E-274"},273.397940008672,null,1.47,"[NR] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-272,"d":"2.00E-272"},271.698970004336,"(EA)",0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs7970695",12,121424861,"rs7310409","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-A","rs7310409",0,7310409,"intron_variant",0,0.39,{"v":8e-269,"d":"8.00E-269"},268.096910013008,null,0.147,"[0.14-0.15] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[31,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-268,"d":"5.00E-268"},267.301029995663,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,"NR",{"v":1e-266,"d":"1.00E-266"},266,null,0.122,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-?","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.43,{"v":4E-264,"d":"4.00E-264"},263.397940008672,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":4E-262,"d":"4.00E-262"},261.397940008672,null,0.221,"[NR] unit decrease","NR [NR] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-?","rs174547",0,174547,"intron_variant",0,"NR",{"v":8e-262,"d":"8.00E-262"},261.096910013008,"(LA/PUFA)",0.57,"[0.53-0.61] unit increase","Illumina [~ 7700000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3642,{"v":3e-259,"d":"3.00E-259"},258.52287874528,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0149,{"v":3e-257,"d":"3.00E-257"},256.52287874528,null,0.3952,"[0.37-0.42] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.413,{"v":4e-253,"d":"4.00E-253"},252.397940008672,"(Trans-ethnic initial)",0.115,"[0.11-0.12] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[43,"rs142158911",19,11191197,"rs114846969","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19p13.2","NR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,1095,8841,"rs114846969-A","rs114846969",0,114846969,"intergenic_variant",1,0.1172,{"v":2e-252,"d":"2.00E-252"},251.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-251,"d":"3.00E-251"},250.52287874528,"(EA)",0.141,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.393,{"v":4e-251,"d":"4.00E-251"},250.397940008672,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":3e-250,"d":"3.00E-250"},249.52287874528,"(EA)",0.169,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3E-249,"d":"3.00E-249"},248.52287874528,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",0.76,"[0.72-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":4e-249,"d":"4.00E-249"},248.397940008672,{"$nulls":3},"NR [2501549] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2E-247,"d":"2.00E-247"},246.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":2e-245,"d":"2.00E-245"},244.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.798,{"v":8e-244,"d":"8.00E-244"},243.096910013008,"(ABO)",1.087,"[1.07-1.11] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-242,"d":"5.00E-242"},241.301029995663,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":7e-242,"d":"7.00E-242"},241.154901959985,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":5e-241,"d":"5.00E-241"},240.301029995663,null,0.167,"[NR] unit decrease","NR [NR] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":7e-240,"d":"7.00E-240"},239.154901959985,null,16.95,"[16.01-17.89] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-239,"d":"1.00E-239"},239,"(Centrosomal protein of 57 kDa, CEP57.11276.1.3)",1.33,"[1.25-1.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":2e-239,"d":"2.00E-239"},238.698970004336,null,0.115,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93,{"v":8e-239,"d":"8.00E-239"},238.096910013008,null,0.413,"[0.39-0.44] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[43,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":1E-236,"d":"1.00E-236"},236,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1081105",19,45412955,"rs1081105","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1081105-C","rs1081105",0,1081105,"non_coding_transcript_exon_variant",0,0.02756,{"v":1e-231,"d":"1.00E-231"},231,null,32.50298,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,null,{"v":4E-231,"d":"4.00E-231"},230.397940008672,null,64.74,"[62.11-67.37] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1E-230,"d":"1.00E-230"},230,null,0.227,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.215441066,{"v":9e-230,"d":"9.00E-230"},229.04575749056,"(GRN)",0.727792,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[8,"rs668948",2,21299867,"rs577584","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,32922,46922,"rs577584-A","rs577584",0,577584,"intergenic_variant",1,0.6896,{"v":1e-229,"d":"1.00E-229"},229,null,0.1008,"[0.095-0.107] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-228,"d":"9.00E-228"},227.04575749056,null,0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-227,"d":"4.00E-227"},226.397940008672,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19819328,"rs325","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs325-T","rs325",0,325,"intron_variant",0,0.9032,{"v":4e-227,"d":"4.00E-227"},226.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":3E-226,"d":"3.00E-226"},225.52287874528,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":7e-224,"d":"7.00E-224"},223.154901959985,null,0.234,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":8e-222,"d":"8.00E-222"},221.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-G","rs157580",0,157580,"intron_variant",0,0.3949,{"v":8e-220,"d":"8.00E-220"},219.096910013008,null,31.6502,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[31,"rs35120633",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":2e-219,"d":"2.00E-219"},218.698970004336,null,0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,"NR",{"v":3e-218,"d":"3.00E-218"},217.52287874528,null,0.274,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.879,{"v":5e-217,"d":"5.00E-217"},216.301029995663,"(Trans-ethnic initial)",0.17,"[0.16-0.18] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5175,{"v":5e-216,"d":"5.00E-216"},215.301029995663,null,0.114319,"[0.11-0.12] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.367,{"v":1e-213,"d":"1.00E-213"},213,"(Trans-ethnic initial)",0.107,"[0.1-0.11] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.28,{"v":4e-213,"d":"4.00E-213"},212.397940008672,null,0.081,"[0.075-0.087] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[18,"rs10455872",6,161123451,"rs4252185","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","PLG",null,null,"ENSG00000122194",null,null,"rs4252185-C","rs4252185",0,4252185,"intron_variant",0,null,{"v":5e-211,"d":"5.00E-211"},210.301029995663,null,23.93,"[22.64-25.22] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":8e-211,"d":"8.00E-211"},210.096910013008,"(Granulins, GRN.4992.49.1)",0.83,"[0.77-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-210,"d":"4.00E-210"},209.397940008672,"(UBA2)",1.4728388,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":2e-208,"d":"2.00E-208"},207.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,null,{"v":2e-207,"d":"2.00E-207"},206.698970004336,null,49.06,"[46.85-51.27] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[43,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":1E-206,"d":"1.00E-206"},206,"(EA)",0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":5E-205,"d":"5.00E-205"},204.301029995663,"(Protein CEI, C5orf38.6378.2.3)",1.25,"[1.17-1.33] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(Trans-ethnic initial)",0.128,"[0.12-0.14] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(EA)",0.22,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-?","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-203,"d":"1.00E-203"},203,"(levels)",0,"[0.80-23.0] % increase","Illumina [NR] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.228,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":4e-202,"d":"4.00E-202"},201.397940008672,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":5e-202,"d":"5.00E-202"},201.301029995663,null,0.185,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":1e-201,"d":"1.00E-201"},201,"(EA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":3E-201,"d":"3.00E-201"},200.52287874528,"(EA)",0.18,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":2E-200,"d":"2.00E-200"},199.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.13,{"v":2E-199,"d":"2.00E-199"},198.698970004336,null,0.17,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,"NR",{"v":3e-199,"d":"3.00E-199"},198.52287874528,null,0.186,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":1E-194,"d":"1.00E-194"},194,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.072,{"v":5e-193,"d":"5.00E-193"},192.301029995663,"(EA)",0.237,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":9e-193,"d":"9.00E-193"},192.04575749056,"(SELE)",0.963,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[22,"rs7816447",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,"NR",{"v":2E-191,"d":"2.00E-191"},190.698970004336,null,0.181,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73025975,"rs13234131","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13234131-A","rs13234131",0,13234131,"intron_variant",0,0.8853,{"v":4e-191,"d":"4.00E-191"},190.397940008672,null,0.1275,"[0.12-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,0.953,{"v":1E-190,"d":"1.00E-190"},190,"(EA)",0.275,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":3e-190,"d":"3.00E-190"},189.52287874528,"(EA)",0.231,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":1e-189,"d":"1.00E-189"},189,"(EA)",0.176,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":1e-188,"d":"1.00E-188"},188,null,0.107,"[NR] unit increase","NR [NR] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":3E-187,"d":"3.00E-187"},186.52287874528,null,0.193,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61581656,"rs174559","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","11q12.2",null,"FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174559-?","rs174559",0,174559,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-185,"d":"5.00E-185"},184.301029995663,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.32,{"v":1E-182,"d":"1.00E-182"},182,null,0.119,"[NR] unit increase","NR [NR] (imputed)","N"]
[24,"8:126490499_TA_T",8,126490498,"rs58253018","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs58253018-A","rs58253018",0,58253018,"intron_variant",0,0.3738,{"v":2e-182,"d":"2.00E-182"},181.698970004336,null,0.0984,"[0.092-0.105] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs35120633",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.936,{"v":3e-182,"d":"3.00E-182"},181.52287874528,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":8e-182,"d":"8.00E-182"},181.096910013008,null,0.168,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.067,{"v":5e-181,"d":"5.00E-181"},180.301029995663,"(EA)",0.24,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":5e-181,"d":"5.00E-181"},180.301029995663,null,0.19,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil counts","172,275 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5168,{"v":1E-180,"d":"1.00E-180"},180,null,0.1019119,"[0.095-0.109] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":6e-180,"d":"6.00E-180"},179.221848749616,null,0.1038733,"[0.097-0.111] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs157592",19,45422160,"rs12721051","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs12721051-C","rs12721051",0,12721051,"3_prime_UTR_variant",0,0.8427,{"v":1E-179,"d":"1.00E-179"},179,null,0.1061,"[0.099-0.113] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.288,{"v":2E-179,"d":"2.00E-179"},178.698970004336,"(Trans-ethnic initial)",0.119,"[0.11-0.13] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":4e-179,"d":"4.00E-179"},178.397940008672,null,0.171,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2010-01-13",20037589,"Illig T","2009-12-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20037589","A genome-wide perspective of genetic variation in human metabolism.","Metabolite levels","1,029 European ancestry individuals","1,202 European ancestry individuals","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,"NR",{"v":7e-179,"d":"7.00E-179"},178.154901959985,"(PC aa C36:3/PC aa C36:4)",0.151,"[NR] unit increase","Affymetrix [517480]","N"]
[46,"rs157592",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":2e-178,"d":"2.00E-178"},177.698970004336,null,0.225,"[NR] unit increase","NR [NR] (imputed)","N"]
[22,"rs11986942",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,"NR",{"v":1e-177,"d":"1.00E-177"},177,null,0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,"NR",{"v":5E-177,"d":"5.00E-177"},176.301029995663,null,0.115,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.879,{"v":4E-176,"d":"4.00E-176"},175.397940008672,"(Trans-ethnic initial)",0.155,"[0.14-0.17] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":7E-176,"d":"7.00E-176"},175.154901959985,null,0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,0.678,{"v":2E-175,"d":"2.00E-175"},174.698970004336,"(lysoPhosphatidylcholine acyl C20:4)",0.1652,"[0.15-0.18] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.015,{"v":8E-175,"d":"8.00E-175"},174.096910013008,null,0.325,"[0.3-0.35] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":1E-173,"d":"1.00E-173"},173,null,0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,0.6793,{"v":9e-172,"d":"9.00E-172"},171.04575749056,"(Phosphatidylcholine diacyl C38:4)",0.1408,"[0.13-0.15] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-171,"d":"2.00E-171"},170.698970004336,{"$nulls":3},"NR [25015711] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.662,{"v":5e-171,"d":"5.00E-171"},170.301029995663,null,0.5227,"[0.49-0.56] unit decrease","Illumina [up to 1980188] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":1e-170,"d":"1.00E-170"},170,null,5.65,"[5.24-6.06] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":2E-170,"d":"2.00E-170"},169.698970004336,null,0.134,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-170,"d":"4.00E-170"},169.397940008672,{"$nulls":3},"NR [2501749] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-169,"d":"1.00E-169"},169,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2e-168,"d":"2.00E-168"},167.698970004336,null,0.148,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs9355288",6,160865645,"rs7769879","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","SLC22A3",null,null,"ENSG00000146477",null,null,"rs7769879-C","rs7769879",0,7769879,"intron_variant",0,null,{"v":4e-168,"d":"4.00E-168"},167.397940008672,null,6.74,"[6.27-7.21] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[30,"rs174564",11,61579760,"rs174555","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)","8,631 European ancestry individuals","NA","11q12.2","FTH1, C11orf9, FADS1, DAGLA, FADS2, FEN1, C11orf10, FADS3, RAB3IL1, BEST1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174555-T","rs174555",0,174555,"intron_variant",0,0.71,{"v":5E-168,"d":"5.00E-168"},167.301029995663,null,0.39,"[NR] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":4E-167,"d":"4.00E-167"},166.397940008672,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum eosinophil basophil counts","171,771 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5168,{"v":7e-167,"d":"7.00E-167"},166.154901959985,null,0.09799102,"[0.091-0.105] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":4E-165,"d":"4.00E-165"},164.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":2e-164,"d":"2.00E-164"},163.698970004336,"(EA)",0.199,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-164,"d":"2.00E-164"},163.698970004336,{"$nulls":3},"NR [2501543] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":3e-164,"d":"3.00E-164"},163.52287874528,null,0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-164,"d":"4.00E-164"},163.397940008672,null,0.144,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61552680,"rs174537","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174537-T","rs174537",0,174537,"non_coding_transcript_exon_variant",0,0.6648,{"v":4e-164,"d":"4.00E-164"},163.397940008672,null,0.5254,"[0.49-0.56] unit decrease","Illumina [up to 1980188] (imputed)","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.897,{"v":9e-164,"d":"9.00E-164"},163.04575749056,"(EA)",0.184,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161005610,"rs55730499","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,null,{"v":4e-163,"d":"4.00E-163"},162.397940008672,null,16.77,"[15.63-17.91] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":6e-163,"d":"6.00E-163"},162.221848749616,null,0.163,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,"NR",{"v":7e-163,"d":"7.00E-163"},162.154901959985,null,0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1081105",19,45412955,"rs1081105","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1081105-?","rs1081105",0,1081105,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-162,"d":"1.00E-162"},162,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-162,"d":"1.00E-162"},162,"(CUB and zona pellucida-like domain-containing protein 1, CUZD1.7943.16.3)",1.14,"[1.06-1.22] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":3E-162,"d":"3.00E-162"},161.52287874528,null,0.161,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.897,{"v":4e-162,"d":"4.00E-162"},161.397940008672,"(EA)",0.184,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs3925681",19,45421100,"rs3925681","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1",null,null,"ENSG00000130208",null,null,"rs3925681-?","rs3925681",0,3925681,"intron_variant",0,"NR",{"v":7e-162,"d":"7.00E-162"},161.154901959985,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":2e-161,"d":"2.00E-161"},160.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs287",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,"NR",{"v":4e-161,"d":"4.00E-161"},160.397940008672,null,0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3798,{"v":3E-160,"d":"3.00E-160"},159.52287874528,null,0.0748,"[0.069-0.08] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[43,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":9e-160,"d":"9.00E-160"},159.04575749056,"(EA)",0.191,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":4E-159,"d":"4.00E-159"},158.397940008672,"(Protein CEI, C5orf38.6378.2.3)",0.82,"[0.76-0.88] unit increase","Affymetrix [10572788] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2e-158,"d":"2.00E-158"},157.698970004336,"(EA)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0194,{"v":6E-158,"d":"6.00E-158"},157.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[22,"rs7816447",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.896,{"v":9E-158,"d":"9.00E-158"},157.04575749056,"(EA)",0.182,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","11q23.3","APO-cluster","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":2e-157,"d":"2.00E-157"},156.698970004336,null,0.244,"[0.23-0.26] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2009-09-29",19734902,"Harold D","2009-09-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19734902","Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.","Alzheimer's disease","3,941 European ancestry cases, 7,848 European ancestry controls","2,023 European ancestry cases, 2,340 European ancestry controls","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,0.15,{"v":2e-157,"d":"2.00E-157"},156.698970004336,null,2.53,"[2.37-2.71]","Illumina [529205]","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":2e-157,"d":"2.00E-157"},156.698970004336,"(EA)",0.174,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-157,"d":"3.00E-157"},156.52287874528,null,0.194,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291312,"rs548145","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24367,55477,"rs548145-T","rs548145",0,548145,"intergenic_variant",1,0.2416,{"v":6e-156,"d":"6.00E-156"},155.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[46,"rs6859",19,45382034,"rs6859","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs6859-?","rs6859",0,6859,"3_prime_UTR_variant",0,"NR",{"v":1E-155,"d":"1.00E-155"},155,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.6,{"v":9e-155,"d":"9.00E-155"},154.04575749056,"(Triglycerides in very large HDL)",0.26,"[0.24-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[22,"rs7816447",8,19824563,"rs1059611","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs1059611-?","rs1059611",0,1059611,"3_prime_UTR_variant",0,"NR",{"v":1e-154,"d":"1.00E-154"},154,null,0.1698,"[0.16-0.18] unit decrease novel","Illumina [6108953] (imputed)","N"]
[18,"rs10455872",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.069,{"v":3e-154,"d":"3.00E-154"},153.52287874528,null,0.337,"[0.31-0.36] unit increase","Affymetrix [7947838] (imputed)","N"]
[18,"rs10455872",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.0686,{"v":3e-154,"d":"3.00E-154"},153.52287874528,null,0.3368,"[0.31-0.36] unit increase","NR [8041861] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-154,"d":"4.00E-154"},153.397940008672,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,"NR",{"v":4e-154,"d":"4.00E-154"},153.397940008672,null,0.07,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-154,"d":"9.00E-154"},153.04575749056,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.0693,{"v":1E-153,"d":"1.00E-153"},153,null,0.3122,"[0.29-0.34] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","C11orf10","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":8e-153,"d":"8.00E-153"},152.096910013008,null,0.07,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[22,"rs7816447",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.879,{"v":1e-152,"d":"1.00E-152"},152,"(EA)",0.168,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs6859",19,45382034,"rs6859","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","PVRL2","NECTIN2",null,null,"ENSG00000130202",null,null,"rs6859-A","rs6859",0,6859,"3_prime_UTR_variant",0,0.4218,{"v":1e-152,"d":"1.00E-152"},152,null,26.320562,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-A","rs1535",0,1535,"intron_variant",0,"NR",{"v":3E-152,"d":"3.00E-152"},151.52287874528,null,0.07,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[30,"rs174564",11,61551356,"rs174535","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","C11orf9","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174535-T","rs174535",0,174535,"synonymous_variant",0,"NR",{"v":1e-151,"d":"1.00E-151"},151,null,0.07,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[18,"rs3777411",6,160498049,"rs3777404","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","6q25.3","NR","IGF2R",null,null,"ENSG00000197081",null,null,"rs3777404-A","rs3777404",0,3777404,"intron_variant",0,0.14,{"v":3e-151,"d":"3.00E-151"},150.52287874528,"(Cation-independent mannose-6-phosphate receptor, IGF2R.3676.15.3)",0.85,"[0.79-0.91] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-151,"d":"4.00E-151"},150.397940008672,{"$nulls":3},"NR [25015711] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.13,{"v":1e-149,"d":"1.00E-149"},149,null,0.155,"[NR] unit increase","NR [NR] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.346,{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix [NR]","N"]
[46,"rs157592",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":1e-149,"d":"1.00E-149"},149,null,0.197,"[NR] unit increase","NR [NR] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2012-08-14",22832961,"Kamboh MI","2012-05-15","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/22832961","Genome-wide association study of Alzheimer's disease.","Alzheimer's disease","1,291 European ancestry cases, 938 European ancestry controls","509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls","19q13.32","APOE, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-149,"d":"8.00E-149"},148.096910013008,null,3.45,"[NR]","Illumina [2543888] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3E-148,"d":"3.00E-148"},147.52287874528,"(glucose/mannose)",0.041,"[0.037-0.045] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":4e-148,"d":"4.00E-148"},147.397940008672,"(Cardiotrophin-1, CTF1.13732.79.3)",0.8,"[0.74-0.86] unit increase","Affymetrix [10572788] (imputed)","N"]
[24,"rs2954038",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7181,{"v":7e-148,"d":"7.00E-148"},147.154901959985,null,0.0776,"[0.072-0.083] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.892,{"v":2e-147,"d":"2.00E-147"},146.698970004336,"(EA)",0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-147,"d":"2.00E-147"},146.698970004336,"(VPS29)",1.2477906,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","8,631 European ancestry individuals","NA","11q12.2","FTH1, INCENP, FADS1, FADS2, SCGB2A1, SCGB1D1, SCGB2A2, RAB3IL1, AHNAK, C11orf9, DAGLA, FEN1, FADS3, SYT7, BEST1","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.3,{"v":7e-147,"d":"7.00E-147"},146.154901959985,"(Conditioned on rs174547)",2.49,"[2.29-2.69] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[22,"rs11986942",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.7,{"v":9e-147,"d":"9.00E-147"},146.04575749056,"(EA)",0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":9e-147,"d":"9.00E-147"},146.04575749056,null,7.14,"[6.57-7.71] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":1E-146,"d":"1.00E-146"},146,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.7,{"v":1E-146,"d":"1.00E-146"},146,"(EA)",0.115,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-145,"d":"1.00E-145"},145,null,0.167,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2e-145,"d":"2.00E-145"},144.698970004336,null,0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":1e-144,"d":"1.00E-144"},144,null,0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs28399637",19,45324138,"rs28399637","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","BCAM","BCAM",null,null,"ENSG00000187244",null,null,"rs28399637-A","rs28399637",0,28399637,"intron_variant",0,0.3156,{"v":2e-143,"d":"2.00E-143"},142.698970004336,null,25.508192,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.8416,{"v":1E-142,"d":"1.00E-142"},142,null,0.093,"[0.086-0.1] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":2e-142,"d":"2.00E-142"},141.698970004336,null,0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":7e-142,"d":"7.00E-142"},141.154901959985,null,0.25,"[0.23-0.27] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,0.6803,{"v":9e-141,"d":"9.00E-141"},140.04575749056,"(Phosphatidylcholine diacyl C36:4)",0.1157,"[0.11-0.12] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[37,"rs1077835",15,58723939,"rs2070895","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":1e-140,"d":"1.00E-140"},140,null,0.1322,"[0.12-0.14] unit increase novel","Illumina [6108953] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-140,"d":"4.00E-140"},139.397940008672,null,0.139,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)","8,631 European ancestry individuals","NA","11q12.2","C11orf9, FADS1, FADS2, DAGLA, FEN1, C11orf10, FADS3, RAB3IL1, BEST1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.674,{"v":4e-140,"d":"4.00E-140"},139.397940008672,null,0.05,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[22,"rs11986942",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,"NR",{"v":1E-139,"d":"1.00E-139"},139,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61564299,"rs4246215","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FEN1","FEN1, FADS2",null,null,"ENSG00000168496, ENSG00000134824",null,null,"rs4246215-T","rs4246215",0,4246215,"3_prime_UTR_variant",0,"NR",{"v":1E-139,"d":"1.00E-139"},139,null,0.07,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.32,{"v":3e-139,"d":"3.00E-139"},138.52287874528,null,0.1,"[NR] unit increase","NR [NR] (imputed)","N"]
[22,"rs11986942",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,"NR",{"v":3e-139,"d":"3.00E-139"},138.52287874528,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":9e-139,"d":"9.00E-139"},138.04575749056,null,0.236,"[0.22-0.26] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73001021,"rs35173225","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,7900,6503,"rs35173225-T","rs35173225",0,35173225,"intergenic_variant",1,0.108,{"v":1e-137,"d":"1.00E-137"},137,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-137,"d":"4.00E-137"},136.397940008672,"(Proteasome activator complex subunit 1, PSME1.5918.5.3)",1.06,"[0.98-1.14] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":8e-137,"d":"8.00E-137"},136.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1081105",19,45412955,"rs1081105","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1081105-?","rs1081105",0,1081105,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-136,"d":"1.00E-136"},136,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.288,{"v":3e-136,"d":"3.00E-136"},135.52287874528,"(Trans-ethnic initial)",0.0995,"[0.092-0.107] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-136,"d":"5.00E-136"},135.301029995663,"(EA)",0.195,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs287",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.731,{"v":8E-136,"d":"8.00E-136"},135.096910013008,"(EA)",0.115,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":7e-135,"d":"7.00E-135"},134.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":9e-135,"d":"9.00E-135"},134.04575749056,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":2e-134,"d":"2.00E-134"},133.698970004336,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.981,{"v":4e-134,"d":"4.00E-134"},133.397940008672,"(EA)",0.481,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":5e-134,"d":"5.00E-134"},133.301029995663,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte counts","171,643 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5176,{"v":7e-134,"d":"7.00E-134"},133.154901959985,null,0.08836465,"[0.081-0.095] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":3e-133,"d":"3.00E-133"},132.52287874528,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":6e-133,"d":"6.00E-133"},132.221848749616,null,8.76,"[7.98-9.54] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":7e-133,"d":"7.00E-133"},132.154901959985,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2E-132,"d":"2.00E-132"},131.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":6e-132,"d":"6.00E-132"},131.221848749616,{"$nulls":3},"NR [2501549] (imputed)","N"]
[46,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,0.923,{"v":3E-131,"d":"3.00E-131"},130.52287874528,"(EA)",0.24,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":6e-131,"d":"6.00E-131"},130.221848749616,null,5.41,"[4.94-5.88] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":9e-131,"d":"9.00E-131"},130.04575749056,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.693,{"v":2e-130,"d":"2.00E-130"},129.698970004336,"(EA)",0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,"NR",{"v":2e-130,"d":"2.00E-130"},129.698970004336,null,0.137,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":3e-130,"d":"3.00E-130"},129.52287874528,null,0.131,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-129,"d":"1.00E-129"},129,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45415640,"rs445925","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":1e-129,"d":"1.00E-129"},129,"(Asian initial, BMI unadjusted)",0.523,"[0.48-0.56] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,"NR",{"v":2e-128,"d":"2.00E-128"},127.698970004336,null,0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116647607,"rs2160669","2014-05-13",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","8,743 East Asian ancestry individuals","11q23.3","A4, C3, A1, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs2160669-?","rs2160669",0,2160669,"3_prime_UTR_variant",0,0.73,{"v":3e-128,"d":"3.00E-128"},127.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[34,"rs11065358",12,121420807,"rs1183910","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-A","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":6e-128,"d":"6.00E-128"},127.221848749616,{"$nulls":3},"NR [2501749] (imputed)","N"]
[22,"rs7816447",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":8e-128,"d":"8.00E-128"},127.096910013008,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs11065358",12,121420807,"rs1183910","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-A","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":8e-128,"d":"8.00E-128"},127.096910013008,{"$nulls":3},"NR [2501549] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":1E-127,"d":"1.00E-127"},127,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":2e-127,"d":"2.00E-127"},126.698970004336,null,0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":3e-126,"d":"3.00E-126"},125.52287874528,"(EA)",0.14,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs7970695",12,121420260,"rs7979473","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7979473-?","rs7979473",0,7979473,"intron_variant",0,"NR",{"v":3e-126,"d":"3.00E-126"},125.52287874528,null,0.09719,"[0.089-0.105] unit increase novel","Illumina [6108953] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of granulocytes","170,536 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.517,{"v":4e-126,"d":"4.00E-126"},125.397940008672,null,0.08525002,"[0.078-0.092] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":7E-126,"d":"7.00E-126"},125.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":1E-125,"d":"1.00E-125"},125,"(EA)",0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58726744,"rs261334","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-?","rs261334",0,261334,"intron_variant",0,"NR",{"v":1E-125,"d":"1.00E-125"},125,"(Triglycerides in very large HDL, conditioned)",0.2686627,"[0.25-0.29] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":2E-125,"d":"2.00E-125"},124.698970004336,null,0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,"NR",{"v":2E-125,"d":"2.00E-125"},124.698970004336,null,0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.725,{"v":2E-125,"d":"2.00E-125"},124.698970004336,"(Asian initial, BMI unadjusted)",0.279,"[0.26-0.3] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,0.688,{"v":7E-125,"d":"7.00E-125"},124.154901959985,"(EA)",0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":8e-125,"d":"8.00E-125"},124.096910013008,"(ADGRF5)",0.815,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[34,"rs11065358",12,121420807,"rs1183910","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-G","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":2e-124,"d":"2.00E-124"},123.698970004336,null,0.149,"[0.14-0.16] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":1e-123,"d":"1.00E-123"},123,"(EA)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs548179580",1,25747230,"rs586178","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","1p36.11",null,"RHCE",null,null,"ENSG00000188672",null,null,"rs586178-?","rs586178",0,586178,"missense_variant",0,"NR",{"v":3e-123,"d":"3.00E-123"},122.52287874528,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alkaline phosphatase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.8,{"v":3e-123,"d":"3.00E-123"},122.52287874528,null,8.8,"[7.40-10.2] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[22,"rs7816447",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,"NR",{"v":9e-123,"d":"9.00E-123"},122.04575749056,null,0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,0.92,{"v":2e-122,"d":"2.00E-122"},121.698970004336,"(EA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs287",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,"NR",{"v":7e-122,"d":"7.00E-122"},121.154901959985,null,0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-122,"d":"8.00E-122"},121.096910013008,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-121,"d":"1.00E-121"},121,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":2E-121,"d":"2.00E-121"},120.698970004336,null,0.126,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs1692821",8,11705870,"rs1736089","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1736089-G","rs1736089",0,1736089,"non_coding_transcript_exon_variant",0,0.748,{"v":2E-121,"d":"2.00E-121"},120.698970004336,"(CTSB)",0.612,"[0.56-0.66] unit decrease","Illumina [> 1000000] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-A","rs2954022",0,2954022,"intron_variant",0,0.47,{"v":7e-121,"d":"7.00E-121"},120.154901959985,"(Trans-ethnic initial)",0.078,"[0.072-0.084] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[37,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":8e-121,"d":"8.00E-121"},120.096910013008,null,0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-120,"d":"1.00E-120"},120,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06,{"v":2E-120,"d":"2.00E-120"},119.698970004336,"(Free cholesterol in large LDL)",0.59,"[0.53-0.65] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2E-120,"d":"2.00E-120"},119.698970004336,"(Selenoprotein S, VIMP.11286.78.3)",1.01,"[0.93-1.09] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":2E-120,"d":"2.00E-120"},119.698970004336,null,0.137,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of white cells","172,378 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5168,{"v":3e-120,"d":"3.00E-120"},119.52287874528,null,0.08283769,"[0.076-0.09] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":3e-120,"d":"3.00E-120"},119.52287874528,null,0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":6e-120,"d":"6.00E-120"},119.221848749616,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs28399637",19,45324138,"rs28399637","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCAM",null,null,"ENSG00000187244",null,null,"rs28399637-?","rs28399637",0,28399637,"intron_variant",0,"NR",{"v":7e-120,"d":"7.00E-120"},119.154901959985,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":1E-119,"d":"1.00E-119"},119,null,0.208,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-119,"d":"1.00E-119"},119,"(Quinone oxidoreductase-like protein 1, CRYZL1.9207.60.3)",1,"[0.92-1.08] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":3e-119,"d":"3.00E-119"},118.52287874528,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs6938647",6,160986915,"rs6938647","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs6938647-A","rs6938647",0,6938647,"intron_variant",0,null,{"v":7e-119,"d":"7.00E-119"},118.154901959985,null,5.47,"[4.76-6.18] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-118,"d":"1.00E-118"},118,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":3e-118,"d":"3.00E-118"},117.52287874528,null,0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":2e-117,"d":"2.00E-117"},116.698970004336,null,0.08,"[0.08-0.09] unit increase","Illumina [4642479] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":4e-117,"d":"4.00E-117"},116.397940008672,null,6.99,"[6.4-7.58] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":8e-117,"d":"8.00E-117"},116.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":8e-117,"d":"8.00E-117"},116.096910013008,null,0.089,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-116,"d":"3.00E-116"},115.52287874528,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":7e-116,"d":"7.00E-116"},115.154901959985,null,0.101,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-C","rs174547",0,174547,"intron_variant",0,0.32,{"v":9e-116,"d":"9.00E-116"},115.04575749056,"(SM-3 + 152 other traits)",0.178,"[NR] unit decrease","Affymetrix, Illumina [534665]","N"]
[46,"rs11556505",19,45395619,"rs2075650","2014-12-02",24755620,"Perez-Palma E","2014-04-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24755620","Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.","Alzheimer's disease","2,540 European ancestry cases, 2,029 European ancestry controls","NA","19q13.32","APOE, BCAM, PVR, EXOC3L2, TOMM40, PVRL2, BCL3, APOC1","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,null,{"v":9e-116,"d":"9.00E-116"},115.04575749056,null,4.48,"[NR]","Affymetrix, Illumina [1216213] (imputed)","N"]
[8,"rs61539677",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,"NR",{"v":1e-115,"d":"1.00E-115"},115,null,0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":2e-115,"d":"2.00E-115"},114.698970004336,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.12,{"v":2e-115,"d":"2.00E-115"},114.698970004336,null,13.64,"[12.37-14.91] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","up to 4,420 African ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,0.13,{"v":3e-115,"d":"3.00E-115"},114.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":5e-115,"d":"5.00E-115"},114.301029995663,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1e-114,"d":"1.00E-114"},114,"(ROBO4)",0.73,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hypothyroidism","approximately 459,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-114,"d":"1.00E-114"},114,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":2e-114,"d":"2.00E-114"},113.698970004336,"(Complement C1q tumor necrosis factor-related protein 1, C1QTNF1.6304.8.3)",0.64,"[0.58-0.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-114,"d":"2.00E-114"},113.698970004336,null,0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.3,{"v":4e-114,"d":"4.00E-114"},113.397940008672,null,4.05,"[3.68-4.42] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":6e-114,"d":"6.00E-114"},113.221848749616,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.3261,{"v":1e-113,"d":"1.00E-113"},113,null,0.26576465,"[0.24-0.29] mg/dl increase","Illumina [24111857] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":2E-113,"d":"2.00E-113"},112.698970004336,null,0.217,"[0.2-0.24] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2E-113,"d":"2.00E-113"},112.698970004336,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":1e-112,"d":"1.00E-112"},112,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3e-112,"d":"3.00E-112"},111.52287874528,null,0.119,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63107526,"rs995000","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.3454,{"v":6e-112,"d":"6.00E-112"},111.221848749616,null,0.0618,"[0.056-0.067] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs11986942",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.7,{"v":2e-111,"d":"2.00E-111"},110.698970004336,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,"NR",{"v":3e-111,"d":"3.00E-111"},110.52287874528,null,0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":5e-111,"d":"5.00E-111"},110.301029995663,null,6.83,"[6.2-7.46] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[47,"rs8111874",19,49206674,"rs601338","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs601338-A","rs601338",0,601338,"stop_gained",0,0.507,{"v":9e-111,"d":"9.00E-111"},110.04575749056,"(Protein FAM3D, FAM3D.13102.1.3)",0.51,"[0.47-0.55] unit decrease","Affymetrix [10572788] (imputed)","N"]
[19,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs34121855",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.7,{"v":1e-110,"d":"1.00E-110"},110,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.117,{"v":2e-110,"d":"2.00E-110"},109.698970004336,"(Trans-ethnic initial)",0.115,"[0.1-0.13] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":7e-110,"d":"7.00E-110"},109.154901959985,null,0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":2E-109,"d":"2.00E-109"},108.698970004336,null,0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":3e-109,"d":"3.00E-109"},108.52287874528,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,0.688,{"v":5e-109,"d":"5.00E-109"},108.301029995663,"(EA)",0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58680178,"rs261291","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-?","rs261291",0,261291,"intron_variant",0,"NR",{"v":7e-109,"d":"7.00E-109"},108.154901959985,null,0.1158,"[0.11-0.13] unit increase novel","Illumina [6108953] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,null,0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of granulocytes","170,672 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.517,{"v":5E-108,"d":"5.00E-108"},107.301029995663,null,0.07881358,"[0.072-0.086] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":1E-107,"d":"1.00E-107"},107,null,0.076,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[24,"rs112875651",8,126500031,"rs28601761","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.5747,{"v":4e-106,"d":"4.00E-106"},105.397940008672,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.879,{"v":5e-106,"d":"5.00E-106"},105.301029995663,"(EA)",0.127,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11600380",11,116665079,"rs9804646","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-?","rs9804646",0,9804646,"intergenic_variant",1,"NR",{"v":5e-106,"d":"5.00E-106"},105.301029995663,null,0.1509,"[0.14-0.16] unit decrease novel","Illumina [6108953] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","RP11-115J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1054,{"v":1e-105,"d":"1.00E-105"},105,null,0.0954,"[0.087-0.104] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs58065809",11,116999225,"rs9326248","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","11q23.3","RP11-109L13.1, TAGLN, PCSK7, PAFAH1B2, SIDT2, RP11-109L13.5, AP000892.6","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,9328,7019,"rs9326248-T","rs9326248",0,9326248,"intergenic_variant",1,0.2386935,{"v":2e-105,"d":"2.00E-105"},104.698970004336,"(Proprotein convertase subtilisin/kexin type 7)",0.9929,"[0.91-1.07] unit decrease","Affymetrix [509946]","N"]
[18,"rs56393506",6,161089307,"rs56393506","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,null,{"v":3e-105,"d":"3.00E-105"},104.52287874528,null,7.07,"[6.37-7.77] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-04-30",28714976,"Sims R","2017-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714976","Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.","Alzheimer's disease (late onset)","up to 16,097 European ancestry cases, up to 18,077 European ancestry controls","up to 20,693 European ancestry cases, up to 30,266 European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-105,"d":"3.00E-105"},104.52287874528,null,2.3065467,null,"Illumina [241551]","N"]
[18,"rs139399782",6,161137663,"rs4252109","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","PLG",null,null,"ENSG00000122194",null,null,"rs4252109-G","rs4252109",0,4252109,"intron_variant",0,null,{"v":5e-105,"d":"5.00E-105"},104.301029995663,null,4.91,"[4.32-5.5] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[37,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,"NR",{"v":5e-105,"d":"5.00E-105"},104.301029995663,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs34121855",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,"NR",{"v":6e-105,"d":"6.00E-105"},104.221848749616,null,0.106,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":8e-105,"d":"8.00E-105"},104.096910013008,"(EA)",0.102,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":9e-105,"d":"9.00E-105"},104.04575749056,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":7e-104,"d":"7.00E-104"},103.154901959985,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.897,{"v":9e-104,"d":"9.00E-104"},103.04575749056,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,0.44,{"v":9e-104,"d":"9.00E-104"},103.04575749056,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs287",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.731,{"v":2e-103,"d":"2.00E-103"},102.698970004336,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.897,{"v":2e-103,"d":"2.00E-103"},102.698970004336,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-102,"d":"1.00E-102"},102,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[37,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,"NR",{"v":2e-102,"d":"2.00E-102"},101.698970004336,null,0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs61539677",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,"NR",{"v":3e-101,"d":"3.00E-101"},100.52287874528,null,0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":6e-101,"d":"6.00E-101"},100.221848749616,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":8e-101,"d":"8.00E-101"},100.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[37,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":8e-101,"d":"8.00E-101"},100.096910013008,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":2E-100,"d":"2.00E-100"},99.698970004336,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs61539677",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,0.677,{"v":3e-100,"d":"3.00E-100"},99.5228787452803,"(EA)",0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56989590,"rs247616","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.67,{"v":4e-100,"d":"4.00E-100"},99.397940008672,null,0.32,"[0.29-0.35] µg/mL increase","Illumina [NR] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":6e-100,"d":"6.00E-100"},99.2218487496163,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":7e-100,"d":"7.00E-100"},99.1549019599857,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.88,{"v":1E-99,"d":"1.00E-99"},99,"(EA)",0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.07994,{"v":1E-99,"d":"1.00E-99"},99,null,21.199877,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-99,"d":"1.00E-99"},99,"(Cardiotrophin-1, CTF1.13732.79.3)",0.92,"[0.84-1] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":2E-99,"d":"2.00E-99"},98.698970004336,"(EA)",0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Smoking behaviour (cigarettes smoked per day)","up to 377,334 European ancestry individuals","NA","19q13.2","NR","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-C","rs56113850",0,56113850,"intron_variant",0,0.555,{"v":4e-99,"d":"4.00E-99"},98.397940008672,null,0.0523096,"[0.047-0.057] unit increase","NR [~ 10000000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":9e-99,"d":"9.00E-99"},98.0457574905606,null,0.115,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[37,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":3E-98,"d":"3.00E-98"},97.5228787452803,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":4e-98,"d":"4.00E-98"},97.397940008672,"(EA)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.12,{"v":1E-97,"d":"1.00E-97"},97,null,2.25,"[2.01-2.49] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs289713",16,57002732,"rs9939224","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs9939224-?","rs9939224",0,9939224,"intron_variant",0,"NR",{"v":1E-97,"d":"1.00E-97"},97,null,0.1861,"[0.17-0.2] unit decrease novel","Illumina [6108953] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-97,"d":"1.00E-97"},97,"(Hemoglobin subunit theta-1, HBQ1.7965.25.3)",0.92,"[0.84-1] unit decrease","Affymetrix [10572788] (imputed)","N"]
[22,"rs7816447",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.896,{"v":2e-97,"d":"2.00E-97"},96.698970004336,"(EA)",0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.17,{"v":2e-97,"d":"2.00E-97"},96.698970004336,null,3.353,"[3.04-3.66] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[46,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,0.846,{"v":3e-97,"d":"3.00E-97"},96.5228787452803,"(EA)",0.136,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-A","rs247617",0,247617,"regulatory_region_variant",1,0.3,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(Total cholesterol in HDL)",0.23,"[0.21-0.25] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":7e-97,"d":"7.00E-97"},96.1549019599857,null,7.09,"[6.42-7.76] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[19,"rs34121855",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.809,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":1e-96,"d":"1.00E-96"},96,"(E-Selectin)",0.9436,"[0.86-1.02] unit decrease","Affymetrix [509946]","N"]
[19,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(EA)",0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":2e-96,"d":"2.00E-96"},95.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(PH and SEC7 domain-containing protein 1, PSD.13055.53.3)",0.66,"[0.6-0.72] unit increase","Affymetrix [10572788] (imputed)","N"]
[22,"rs11986942",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.693,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.39,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,null,1.45,"[1.29-1.61] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.3,{"v":4e-96,"d":"4.00E-96"},95.397940008672,null,4.16,"[3.73-4.59] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[37,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":6e-96,"d":"6.00E-96"},95.2218487496163,null,0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs34121855",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.81,{"v":2E-95,"d":"2.00E-95"},94.698970004336,"(EA)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":3e-95,"d":"3.00E-95"},94.5228787452803,null,0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.569,{"v":3e-95,"d":"3.00E-95"},94.5228787452803,"(Trans-ethnic initial)",0.0733,"[0.066-0.081] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.3216,{"v":3e-95,"d":"3.00E-95"},94.5228787452803,"(Phosphatidylcholine diacyl C38:5)",0.1041,"[0.094-0.114] unit decrease","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":9e-95,"d":"9.00E-95"},94.0457574905606,null,0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-94,"d":"2.00E-94"},93.698970004336,null,0.08881,"[0.08-0.097] unit decrease novel","Illumina [6108953] (imputed)","N"]
[30,"rs174564",11,61551356,"rs174535","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q12.2","FADS1","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174535-T","rs174535",0,174535,"synonymous_variant",0,0.66,{"v":2e-94,"d":"2.00E-94"},93.698970004336,"(1-arachidonoylglycerophosphocholine)",0.056,"[0.05-0.062] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,"NR",{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.167,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal fluid AB1-42 levels","3,146 individuals","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.101,"[0.091-0.111] unit decrease","Illumina [7358575] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0779,{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.41957754,"[0.38-0.46] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-T","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.7072,{"v":6e-94,"d":"6.00E-94"},93.2218487496163,null,0.0604,"[0.055-0.066] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-94,"d":"6.00E-94"},93.2218487496163,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.6225,{"v":7E-94,"d":"7.00E-94"},93.1549019599857,null,0.0556,"[0.05-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs3816117",16,57005479,"rs1532624","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-C","rs1532624",0,1532624,"intron_variant",0,0.57,{"v":9e-94,"d":"9.00E-94"},93.0457574905606,null,0.21,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[31,"rs35120633",11,116662407,"rs3135506","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-C","rs3135506",0,3135506,"missense_variant",0,0.071,{"v":2e-93,"d":"2.00E-93"},92.698970004336,null,0.1053,"[0.095-0.115] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[24,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs4149307",9,107589744,"rs4149307","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149307-T","rs4149307",0,4149307,"intron_variant",0,0.3233,{"v":3e-93,"d":"3.00E-93"},92.5228787452803,null,0.0685,"[0.062-0.075] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(HDL-C.assay, whole)",3.096,"[NR] unit increase","Illumina [335603]","N"]
[38,"rs3816117",16,56995236,"rs1800775","2009-12-29",20031564,"Ridker PM","2009-02-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031564","Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.","HDL cholesterol","18,245 European ancestry females","NA","16q13","SLC12A3, HERPUD1, CETP, NUP93","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.49,{"v":4e-93,"d":"4.00E-93"},92.397940008672,null,3.09,"mg/dL increase","Illumina [~ 318237]","N"]
[3,"rs11591147",1,55505647,"rs11591147","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.98,{"v":2E-92,"d":"2.00E-92"},91.698970004336,null,0.528,"[0.48-0.58] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2E-92,"d":"2.00E-92"},91.698970004336,"(C5orf38)",1.016853,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63107526,"rs995000","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.309,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,"(Trans-ethnic initial)",0.0691,"[0.062-0.076] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,null,0.073,"[0.065-0.081] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q26","intergenic","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,0.0131,{"v":5e-92,"d":"5.00E-92"},91.3010299956639,null,0.5467,"[0.49-0.6] unit increase","NR [8041861] (imputed)","N"]
[24,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":6e-92,"d":"6.00E-92"},91.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":7e-92,"d":"7.00E-92"},91.1549019599857,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,0.146,"[0.13-0.16] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":2E-91,"d":"2.00E-91"},90.698970004336,"(EA)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,3.9972339,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.09,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-91,"d":"4.00E-91"},90.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[13,"rs4704210",5,74656539,"rs12916","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.569,{"v":5E-91,"d":"5.00E-91"},90.3010299956639,"(Trans-ethnic initial)",0.0684,"[0.061-0.075] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,"NR",{"v":5E-91,"d":"5.00E-91"},90.3010299956639,null,0.19,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":7e-91,"d":"7.00E-91"},90.1549019599857,null,0.0724115,"[0.065-0.079] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2E-90,"d":"2.00E-90"},89.698970004336,"(Ubiquitin carboxyl-terminal hydrolase 21, USP21.12681.63.3)",0.49,"[0.45-0.53] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-90,"d":"3.00E-90"},89.5228787452803,"(Inactive gamma-glutamyltranspeptidase 2, GGT2.6334.9.3)",0.88,"[0.8-0.96] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs3925681",19,45421100,"rs3925681","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOC1",null,null,"ENSG00000130208",null,null,"rs3925681-?","rs3925681",0,3925681,"intron_variant",0,"NR",{"v":3e-90,"d":"3.00E-90"},89.5228787452803,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":4E-90,"d":"4.00E-90"},89.397940008672,null,0.118,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569306,"rs174545","2015-07-27",25500335,"Tintle NL","2014-12-02","Prostaglandins Leukot Essent Fatty Acids","www.ncbi.nlm.nih.gov/pubmed/25500335","A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study.","Red blood cell fatty acid levels","2,633 individuals","NA","11q12.2","FADS1, C11orf10, C11orf9, FADS2, FEN1, FADS3, RAB3IL1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174545-?","rs174545",0,174545,"3_prime_UTR_variant",0,0.33,{"v":8E-90,"d":"8.00E-90"},89.096910013008,"(AA)",0.374,"[NR] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2011-06-23",21627779,"Antunez C","2011-05-31","Genome Med","www.ncbi.nlm.nih.gov/pubmed/21627779","The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.","Alzheimer's disease","319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls","4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls","19q13.32","APOE","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":8e-89,"d":"8.00E-89"},88.096910013008,null,1.69,"[NR]","Affymetrix, Illumina [696707] (imputed)","N"]
[8,"rs61539677",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,0.677,{"v":3e-88,"d":"3.00E-88"},87.5228787452803,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.36,{"v":5e-88,"d":"5.00E-88"},87.3010299956639,null,0.123,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.892,{"v":1E-87,"d":"1.00E-87"},87,"(EA)",0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs6938647",6,160986915,"rs6938647","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs6938647-A","rs6938647",0,6938647,"intron_variant",0,null,{"v":2E-87,"d":"2.00E-87"},86.698970004336,null,5.48,"[4.89-6.07] unit decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723479,"rs1077834","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,{"$nulls":3},"NR [2501543] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3e-87,"d":"3.00E-87"},86.5228787452803,"(ARL2)",0.97562826,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.274,{"v":4e-87,"d":"4.00E-87"},86.397940008672,"(East Asian)",0.32,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":5e-87,"d":"5.00E-87"},86.3010299956639,"(HDL.large, whole)",0.729,"[NR] unit increase","Illumina [335603]","N"]
[37,"rs261290",15,58680178,"rs261291","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-C","rs261291",0,261291,"intron_variant",0,0.37,{"v":6e-87,"d":"6.00E-87"},86.2218487496163,null,0.122,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63124465,"rs4495740","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs4495740-T","rs4495740",0,4495740,"intron_variant",0,0.6678,{"v":2e-86,"d":"2.00E-86"},85.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[30,"rs174564",11,61552680,"rs174537","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174537-T","rs174537",0,174537,"non_coding_transcript_exon_variant",0,0.312,{"v":2e-86,"d":"2.00E-86"},85.698970004336,null,0.0617,"[0.056-0.068] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[31,"rs1263151",11,116654435,"rs603446","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13","ZPR1",null,null,"ENSG00000109917",null,null,"rs603446-T","rs603446",0,603446,"intron_variant",0,0.23,{"v":2e-86,"d":"2.00E-86"},85.698970004336,null,0.0876,"[0.079-0.096] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(EA)",0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.4,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(BMI-adjusted)",0.077,"[0.069-0.085] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.28,{"v":2E-85,"d":"2.00E-85"},84.698970004336,null,2.516,"[2.27-2.76] unit decrease","Affymetrix, Illumina [2573667] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":3e-85,"d":"3.00E-85"},84.5228787452803,null,0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.243,{"v":7e-85,"d":"7.00E-85"},84.1549019599857,"(Trans-ethnic initial)",0.0698,"[0.062-0.078] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[31,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,0.945,{"v":9e-85,"d":"9.00E-85"},84.0457574905606,"(EA)",0.193,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61571348,"rs174548","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174548-C","rs174548",0,174548,"5_prime_UTR_variant",0,0.7,{"v":1E-84,"d":"1.00E-84"},84,"(arachidonate (20:4n6))",0.049,"[0.043-0.055] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[38,"rs247617",16,56991363,"rs183130","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,12588,4399,"rs183130-T","rs183130",0,183130,"intergenic_variant",1,0.3073,{"v":1E-84,"d":"1.00E-84"},84,null,0.0549,"[0.049-0.06] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,0.6783,{"v":5e-84,"d":"5.00E-84"},83.3010299956639,"(Phosphatidylcholine acyl-alkyl C36:5)",0.0992,"[0.089-0.109] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[37,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.707,{"v":5e-84,"d":"5.00E-84"},83.3010299956639,"(EA)",0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","Triglyceride levels","1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":7e-84,"d":"7.00E-84"},83.1549019599857,"(additive)",32.91,"[29.62-36.20] unit increase","Affymetrix [583469]","N"]
[19,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.874,{"v":8e-84,"d":"8.00E-84"},83.096910013008,"(EA)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.89,{"v":9e-84,"d":"9.00E-84"},83.0457574905606,null,0.186,"[0.17-0.21] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.6022,{"v":1E-83,"d":"1.00E-83"},83,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-83,"d":"2.00E-83"},82.698970004336,null,3.8717523,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[21,"rs11250098",8,10957723,"rs2409701","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8p23.1",null,"XKR6",null,null,"ENSG00000171044",null,null,"rs2409701-?","rs2409701",0,2409701,"intron_variant",0,"NR",{"v":3e-83,"d":"3.00E-83"},82.5228787452803,null,0.0393467,"[0.035-0.043] unit increase","Affymetrix [20259828] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Triglycerides","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":3e-83,"d":"3.00E-83"},82.5228787452803,"(Hispanic)",0.275,"[0.25-0.3] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[46,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,"NR",{"v":6e-83,"d":"6.00E-83"},82.2218487496163,null,0.232,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","TMEM258, FADS1, FADS2, FADS3","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.6762,{"v":1e-82,"d":"1.00E-82"},82,"(Phosphatidylcholine acyl-alkyl C38:4)",0.0799,"[0.072-0.088] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2010-03-17",20147318,"Qi L","2010-02-22","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20147318","Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes.","E-selectin levels","501 European ancestry type 2 diabetes female cases, 504 European ancestry female controls","518 European ancestry female individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.22,{"v":2e-82,"d":"2.00E-82"},81.698970004336,null,17.23,"[NR] ng/ml decrease","Affymetrix [721316]","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-82,"d":"2.00E-82"},81.698970004336,"(Phosphatidylcholine with diacyl residue sum C36:3/Phosphatidylcholine with diacyl residue sum C36:4)",0.786835,"[0.71-0.86] unit increase","Illumina [up to 9281895] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.295,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,"(Trans-ethnic initial)",0.0758,"[0.069-0.083] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[24,"rs2954021",8,126478450,"rs2001846","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27803,731,"rs2001846-T","rs2001846",0,2001846,"intergenic_variant",1,0.4479,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,null,0.0539,"[0.048-0.059] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[46,"rs157595",19,45425460,"rs157595","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-A","rs157595",0,157595,"intergenic_variant",1,0.39,{"v":5e-82,"d":"5.00E-82"},81.3010299956639,null,0.096,"[0.086-0.106] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":1e-81,"d":"1.00E-81"},81,"(HDL-C.by.NMR, whole)",2.658,"[NR] unit increase","Illumina [335603]","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-81,"d":"4.00E-81"},80.397940008672,"(Guanine nucleotide-binding protein G(k) subunit alpha, GNAI3.12650.43.3)",0.84,"[0.76-0.92] unit increase","Affymetrix [10572788] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":5e-81,"d":"5.00E-81"},80.3010299956639,"(IL3RA)",0.613,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":5e-81,"d":"5.00E-81"},80.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-80,"d":"2.00E-80"},79.698970004336,"(CUZD1)",0.9441912,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":4e-80,"d":"4.00E-80"},79.397940008672,null,0.075,"[NR] unit decrease","NR [NR] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":4e-80,"d":"4.00E-80"},79.397940008672,"(Vascular endothelial growth factor receptor 2, KDR.3651.50.5)",0.58,"[0.52-0.64] unit decrease","Affymetrix [10572788] (imputed)","N"]
[22,"rs7816447",8,19819328,"rs325","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs325-?","rs325",0,325,"intron_variant",0,"NR",{"v":2E-79,"d":"2.00E-79"},78.698970004336,null,0.1483,"[0.13-0.16] unit increase novel","Illumina [6108953] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,"NR",{"v":4E-79,"d":"4.00E-79"},78.397940008672,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-78,"d":"2.00E-78"},77.698970004336,"(women)",0.09,"[NR] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[46,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,0.964,{"v":2E-78,"d":"2.00E-78"},77.698970004336,"(EA)",0.237,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":3e-78,"d":"3.00E-78"},77.5228787452803,"(EA)",0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q21.3","ALDH1A2","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.3451,{"v":4E-78,"d":"4.00E-78"},77.397940008672,null,0.0522,"[0.047-0.058] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[13,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":5e-78,"d":"5.00E-78"},77.3010299956639,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,"NR",{"v":7e-78,"d":"7.00E-78"},77.1549019599857,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.4,{"v":8E-78,"d":"8.00E-78"},77.096910013008,null,0.073,"[NR] unit increase","NR [NR] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":8E-78,"d":"8.00E-78"},77.096910013008,"(HDL.mean.size, whole)",0.086,"[NR] unit increase","Illumina [335603]","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06071,{"v":8E-78,"d":"8.00E-78"},77.096910013008,null,17.11,"[15.31-18.91] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-77,"d":"1.00E-77"},77,"(mannose)",0.044,"[0.04-0.048] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[13,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,"NR",{"v":1e-77,"d":"1.00E-77"},77,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":1e-77,"d":"1.00E-77"},77,"(Trans-ethnic initial)",0.0622,"[0.055-0.069] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":4e-77,"d":"4.00E-77"},76.397940008672,null,0.137,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":5e-77,"d":"5.00E-77"},76.3010299956639,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":6e-77,"d":"6.00E-77"},76.2218487496163,null,3.2625577,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":9e-77,"d":"9.00E-77"},76.0457574905606,null,3.2591338,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[33,"rs35350651",12,111865049,"rs7310615","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Autoimmune traits","approximately 459,000 European ancestry individuals","NA","12q24.12",null,"SH2B3",null,null,"ENSG00000111252",null,null,"rs7310615-?","rs7310615",0,7310615,"intron_variant",0,"NR",{"v":2e-76,"d":"2.00E-76"},75.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-76,"d":"2.00E-76"},75.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-?","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":3e-76,"d":"3.00E-76"},75.5228787452803,null,0.1081,"[0.097-0.12] unit decrease novel","Illumina [6108953] (imputed)","N"]
[37,"rs261290",15,58680643,"rs35853021","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs35853021-?","rs35853021",0,35853021,"intron_variant",0,"NR",{"v":7e-76,"d":"7.00E-76"},75.1549019599857,"(XL-HDL-TG)",0.31,"[0.27-0.35] unit increase","Illumina [~ 7700000] (imputed)","N"]
[10,"rs11887534",2,44066247,"rs11887534","2017-03-10",27094239,"Joshi AD","2016-04-16","Gastroenterology","www.ncbi.nlm.nih.gov/pubmed/27094239","Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.","Gallstone disease","8,720 European ancestry cases,  55,152 European ancestry controls","6,489 European ancestry cases, 62,797 European ancestry controls, 1,499 African American cases, 9,145 African American controls, 1,056 Hispanic cases, 2,403 Hispanic controls","2p21","ABCG8, D19H","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-C","rs11887534",0,11887534,"missense_variant",0,0.07,{"v":2e-75,"d":"2.00E-75"},74.698970004336,"(EA)",1.78,"[1.70–1.86]","Affymetrix, Illumina [at least 2305318] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-75,"d":"2.00E-75"},74.698970004336,"(Lysophosphatidylcholine with acyl residue C20:3/Lysophosphatidylcholine with acyl residue C20:4)",0.753679,"[0.68-0.83] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs5130",11,116704178,"rs7123454","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","NR","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,390,2289,"rs7123454-?","rs7123454",0,7123454,"intergenic_variant",1,"NR",{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.08217,"[0.073-0.091] unit increase novel","Illumina [6108953] (imputed)","N"]
[33,"rs35350651",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5029,{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.06562279,"[0.059-0.073] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-T","rs173539",0,173539,"intergenic_variant",1,0.32,{"v":4e-75,"d":"4.00E-75"},74.397940008672,null,0.25,"[0.21-0.29] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5e-75,"d":"5.00E-75"},74.3010299956639,"(Trans-ethnic initial)",0.137,"[0.12-0.15] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs6859",19,45382034,"rs6859","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs6859-?","rs6859",0,6859,"3_prime_UTR_variant",0,"NR",{"v":6e-75,"d":"6.00E-75"},74.2218487496163,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":1e-74,"d":"1.00E-74"},74,null,0.06470062,"[0.058-0.072] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.845,{"v":1e-74,"d":"1.00E-74"},74,null,0.0566,"[0.051-0.063] unit decrease","Affymetrix [11535925] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.169,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Asian initial, BMI unadjusted)",0.262,"[0.23-0.29] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[42,"rs4939883",18,47181668,"rs2156552","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.178,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Trans-ethnic initial)",0.0793,"[0.07-0.088] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.066,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[38,"rs289713",16,57000885,"rs12720922","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-A","rs12720922",0,12720922,"intron_variant",0,0.17,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.35,"[0.31-0.39] µg/mL increase","Illumina [NR] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,"(Collectin-10, COLEC10.6558.5.3)",0.81,"[0.73-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.4,{"v":5E-74,"d":"5.00E-74"},73.3010299956639,null,0.68,"[NR] unit increase","NR [NR] (imputed)","N"]
[46,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.981,{"v":6e-74,"d":"6.00E-74"},73.2218487496163,"(EA)",0.347,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-73,"d":"1.00E-73"},73,"(Phosphatidylcholine with diacyl residue sum C38:3/Phosphatidylcholine with diacyl residue sum C38:4)",0.747911,"[0.67-0.82] unit increase","Illumina [up to 9281895] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.51,{"v":1E-73,"d":"1.00E-73"},73,null,0.18,"[0.16-0.20] unit decrease","Affymetrix [389878]","N"]
[46,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,0.923,{"v":1E-73,"d":"1.00E-73"},73,"(EA)",0.175,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p21","ABCG8, ABCG5","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.31,{"v":3e-73,"d":"3.00E-73"},72.5228787452803,null,0.079,"[NR] unit increase","NR [NR] (imputed)","N"]
[42,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":3e-73,"d":"3.00E-73"},72.5228787452803,null,0.2326,"[0.21-0.26] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":4E-73,"d":"4.00E-73"},72.397940008672,"(QSOX2)",0.625,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[8,"rs6544366",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":1e-72,"d":"1.00E-72"},72,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-T","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.7073,{"v":1e-72,"d":"1.00E-72"},72,null,0.053,"[0.047-0.059] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)","8,631 European ancestry individuals","NA","11q12.2","FTH1, C11orf9, FADS1, DAGLA, FADS2, FEN1, C11orf10, FADS3, RAB3IL1, BEST1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,0.674,{"v":2e-72,"d":"2.00E-72"},71.698970004336,null,0.02,"[0.018-0.022] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[44,"rs58542926",19,19379549,"rs58542926","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.0692,{"v":3e-72,"d":"3.00E-72"},71.5228787452803,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","2p21","ABCG5, ABCG58","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.31,{"v":4e-72,"d":"4.00E-72"},71.397940008672,null,0.081,"[NR] unit increase","NR [NR] (imputed)","N"]
[46,"rs111606839",19,45452812,"rs1130742","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC2, APOC4-APOC2",null,null,"ENSG00000234906, ENSG00000224916",null,null,"rs1130742-T","rs1130742",0,1130742,"3_prime_UTR_variant",0,0.261,{"v":5e-72,"d":"5.00E-72"},71.3010299956639,"(PH and SEC7 domain-containing protein 2, PSD2.9118.7.3)",0.49,"[0.43-0.55] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":7E-72,"d":"7.00E-72"},71.1549019599857,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":8e-72,"d":"8.00E-72"},71.096910013008,null,0.06311912,"[0.056-0.07] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs28399637",19,45324138,"rs28399637","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","BCAM",null,null,"ENSG00000187244",null,null,"rs28399637-?","rs28399637",0,28399637,"intron_variant",0,"NR",{"v":8e-72,"d":"8.00E-72"},71.096910013008,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,"NR",{"v":1e-71,"d":"1.00E-71"},71,null,0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206145,"rs516316","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Mumps","31,227 European ancestry cases, 54,153 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs516316-C","rs516316",0,516316,"intron_variant",0,0.48,{"v":1e-71,"d":"1.00E-71"},71,null,1.25,"[1.24-1.27]","Illumina [at least 560000] (imputed)","N"]
[8,"rs6544366",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-71,"d":"2.00E-71"},70.698970004336,null,0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.725,{"v":2e-71,"d":"2.00E-71"},70.698970004336,"(Asian initial, BMI unadjusted)",0.182,"[0.16-0.2] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":2e-71,"d":"2.00E-71"},70.698970004336,null,3.2239969,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.92,{"v":3e-71,"d":"3.00E-71"},70.5228787452803,"(Trans-ethnic initial)",0.1,"[0.086-0.114] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":4e-71,"d":"4.00E-71"},70.397940008672,null,0.1558,"[0.14-0.17] unit increase novel","Illumina [6108953] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5E-71,"d":"5.00E-71"},70.3010299956639,"(Trans-ethnic initial)",0.121,"[0.11-0.13] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":9e-71,"d":"9.00E-71"},70.0457574905606,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":1E-70,"d":"1.00E-70"},70,null,0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,0.6792,{"v":2E-70,"d":"2.00E-70"},69.698970004336,"(Phosphatidylcholine acyl-alkyl C38:5)",0.0764,"[0.068-0.085] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[30,"rs174564",11,61571382,"rs174549","2019-04-24",30453627,"Marklund M","2018-11-17","Nutrients","www.ncbi.nlm.nih.gov/pubmed/30453627","Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity.","Fatty acid desaturase activity (serum)","1,453 European ancestry individuals","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174549-A","rs174549",0,174549,"5_prime_UTR_variant",0,0.33,{"v":2E-70,"d":"2.00E-70"},69.698970004336,"(D5D)",null,null,"Illumina [at least 738879] (imputed)","N"]
[46,"rs60049679",19,45429708,"rs60049679","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,7102,353,"rs60049679-?","rs60049679",0,60049679,"regulatory_region_variant",1,"NR",{"v":2E-70,"d":"2.00E-70"},69.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs60049679",19,45429708,"rs60049679","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,7102,353,"rs60049679-?","rs60049679",0,60049679,"regulatory_region_variant",1,"NR",{"v":2E-70,"d":"2.00E-70"},69.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-70,"d":"3.00E-70"},69.5228787452803,null,0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,"NR",{"v":3e-70,"d":"3.00E-70"},69.5228787452803,null,0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":3e-70,"d":"3.00E-70"},69.5228787452803,"(INSR)",0.595,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-?","rs173539",0,173539,"intergenic_variant",1,0.28,{"v":3e-70,"d":"3.00E-70"},69.5228787452803,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[31,"rs2000571",11,116581641,"rs2367970","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,52673,37245,"rs2367970-G","rs2367970",0,2367970,"intergenic_variant",1,"NR",{"v":5e-70,"d":"5.00E-70"},69.3010299956639,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":6e-70,"d":"6.00E-70"},69.2218487496163,"(EA)",0.475,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":7e-70,"d":"7.00E-70"},69.1549019599857,"(CEP57)",0.89456034,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5175,{"v":9e-70,"d":"9.00E-70"},69.0457574905606,null,0.06308641,"[0.056-0.07] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1e-69,"d":"1.00E-69"},69,null,0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":1e-69,"d":"1.00E-69"},69,null,0.121,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":2e-69,"d":"2.00E-69"},68.698970004336,null,0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5028,{"v":2e-69,"d":"2.00E-69"},68.698970004336,null,0.06301181,"[0.056-0.07] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC4, APOC4-APOC2, APOC2, CTB-129P6.11","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.3510532,{"v":2e-69,"d":"2.00E-69"},68.698970004336,"(EA, Granulocyte colony-stimulating factor)",0.7496,"[0.67-0.83] unit increase","Affymetrix [509946]","N"]
[18,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.989,{"v":3e-69,"d":"3.00E-69"},68.5228787452803,"(EA)",0.397,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,"NR",{"v":4e-69,"d":"4.00E-69"},68.397940008672,null,0.382,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":6e-69,"d":"6.00E-69"},68.2218487496163,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45394336,"rs71352238","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs71352238-?","rs71352238",0,71352238,"intron_variant",0,"NR",{"v":7e-69,"d":"7.00E-69"},68.1549019599857,null,3.181876,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,0.92,{"v":1e-68,"d":"1.00E-68"},68,"(EA)",0.162,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (mother's attained age)","412,937 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-68,"d":"1.00E-68"},68,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":2e-68,"d":"2.00E-68"},67.698970004336,"(EA)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,"NR",{"v":3E-68,"d":"3.00E-68"},67.5228787452803,null,0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.701,{"v":3E-68,"d":"3.00E-68"},67.5228787452803,"(Hispanic)",0.235,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":3E-68,"d":"3.00E-68"},67.5228787452803,null,0.153,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,0.3351,{"v":4e-68,"d":"4.00E-68"},67.397940008672,null,0.1542,"[0.14-0.17] unit increase","Illumina [up to 1980188] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.695,{"v":1e-67,"d":"1.00E-67"},67,"(Hispanic)",0.233,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21204025,"rs6544366","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,119492,18160,"rs6544366-T","rs6544366",0,6544366,"intergenic_variant",1,0.2243,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.0549,"[0.049-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[28,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Immature fraction of reticulocytes","170,548 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.06617714,"[0.059-0.074] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs247617",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.7,{"v":2e-67,"d":"2.00E-67"},66.698970004336,"(Hispanic)",0.234,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":3e-67,"d":"3.00E-67"},66.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":3e-67,"d":"3.00E-67"},66.5228787452803,"(ICAM2)",0.593,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.231,{"v":6e-67,"d":"6.00E-67"},66.2218487496163,"(Hispanic)",0.275,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2018-09-05",29455858,"Sung YJ","2018-02-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29455858","A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.","Diastolic blood pressure (cigarette smoking interaction)","80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals","305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals","12q24.12","SH2B3, ATXN2","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,null,{"v":6e-67,"d":"6.00E-67"},66.2218487496163,{"$nulls":3},"Affymetrix, Illumina [18800000] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.785,{"v":8e-67,"d":"8.00E-67"},66.096910013008,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.215,{"v":9e-67,"d":"9.00E-67"},66.0457574905606,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":1e-66,"d":"1.00E-66"},66,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.591,{"v":1e-66,"d":"1.00E-66"},66,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":1e-66,"d":"1.00E-66"},66,"(HDL-C.assay, fasting)",3.094,"[NR] unit increase","Illumina [335603]","N"]
[13,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":2E-66,"d":"2.00E-66"},65.698970004336,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,"NR",{"v":3e-66,"d":"3.00E-66"},65.5228787452803,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,"NR",{"v":3e-66,"d":"3.00E-66"},65.5228787452803,null,0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":4e-66,"d":"4.00E-66"},65.397940008672,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":5e-66,"d":"5.00E-66"},65.3010299956639,null,0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,0.616,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,0.622,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(FAM3D)",0.581,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.86,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(Triglycerides in small VLDL)",0.24,"[0.22-0.26] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[13,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,0.615,{"v":1e-65,"d":"1.00E-65"},65,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.062,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.25,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.07,"[NR] unit decrease","NR [NR] (imputed)","N"]
[30,"rs174564",11,61543499,"rs174528","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","MYRF, TMEM258",null,null,"ENSG00000124920, ENSG00000134825",null,null,"rs174528-T","rs174528",0,174528,"intron_variant",0,0.3337,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.2088,"[0.19-0.23] unit increase","Illumina [up to 1980188] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.105,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-T","rs173539",0,173539,"intergenic_variant",1,0.32,{"v":3E-65,"d":"3.00E-65"},64.5228787452803,"(HDL)",0.255,"[0.23-0.28] mmol/l increase","Illumina [NR] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.3,{"v":1e-64,"d":"1.00E-64"},64,null,0.155,"[0.14-0.17] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,null,0.12,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[31,"rs651821",11,116639104,"rs10790162","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,"(BMI unadjusted)",0.214,"[0.19-0.24] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":2e-64,"d":"2.00E-64"},63.698970004336,null,0.401,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-T","rs174547",0,174547,"intron_variant",0,"NR",{"v":3e-64,"d":"3.00E-64"},63.5228787452803,null,0.02,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[46,"rs429358",19,45411941,"rs429358","2018-02-09",29263008,"Guerreiro R","2018-01-01","Lancet Neurol","www.ncbi.nlm.nih.gov/pubmed/29263008","Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.","Dementia with Lewy bodies","1,216 European ancestry cases, 3,791 European ancestry controls","527 European ancestry cases, 663 European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.14,{"v":3e-64,"d":"3.00E-64"},63.5228787452803,null,2.46,"[2.22-2.74]","Illumina [8397716] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(VLDL.small, whole)",4.219,"[NR] unit decrease","Illumina [335603]","N"]
[26,"rs2740488",9,107664301,"rs1883025","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.243,{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(Trans-ethnic initial)",0.0671,"[0.059-0.075] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.989,{"v":5e-64,"d":"5.00E-64"},63.3010299956639,"(EA)",0.372,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":6e-64,"d":"6.00E-64"},63.2218487496163,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.711,{"v":6e-64,"d":"6.00E-64"},63.2218487496163,"(Hispanic)",0.23,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","C11orf10","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-64,"d":"7.00E-64"},63.1549019599857,null,0.02,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[8,"rs6544366",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":8e-64,"d":"8.00E-64"},63.096910013008,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,"NR",{"v":8e-64,"d":"8.00E-64"},63.096910013008,null,0.359,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs12721028",11,116708413,"rs670","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","APOA1","APOA1-AS, APOA1",null,null,"ENSG00000235910, ENSG00000118137",null,null,"rs670-T","rs670",0,670,"5_prime_UTR_variant",0,0.167,{"v":8e-64,"d":"8.00E-64"},63.096910013008,"(Beta-endorphin, POMC.2558.51.3)",0.54,"[0.48-0.6] unit decrease","Affymetrix [10572788] (imputed)","N"]
[30,"rs174564",11,61551927,"rs174536","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","C11orf9","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174536-A","rs174536",0,174536,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-63,"d":"1.00E-63"},63,null,0.02,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[33,"rs35350651",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":1e-63,"d":"1.00E-63"},63,null,0.403,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-C","rs515135",0,515135,"intergenic_variant",1,0.83,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.135,"[0.12-0.15] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1012,{"v":2e-63,"d":"2.00E-63"},62.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.11,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.162,"[0.14-0.18] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [2501549] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-A","rs1535",0,1535,"intron_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,null,0.02,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-63,"d":"3.00E-63"},62.5228787452803,"(Mediator of RNA polymerase II transcription subunit 4, MED4.14021.81.3)",0.42,"[0.38-0.46] unit increase","Affymetrix [10572788] (imputed)","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":4e-63,"d":"4.00E-63"},62.397940008672,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157581",19,45396219,"rs157582","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157582-?","rs157582",0,157582,"intron_variant",0,"NR",{"v":4e-63,"d":"4.00E-63"},62.397940008672,null,2.7341528,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-A","rs676210",0,676210,"missense_variant",0,0.2052,{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.0546,"[0.048-0.061] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.733,{"v":7e-63,"d":"7.00E-63"},62.1549019599857,"(Hispanic)",0.244,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,"NR",{"v":9e-63,"d":"9.00E-63"},62.0457574905606,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.69,{"v":1E-62,"d":"1.00E-62"},62,"(Hispanic)",0.222,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-04-12",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Free cholesterol levels in large LDL","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.642,"unit decrease","Illumina [15144991] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Dementia and core Alzheimer's disease neuropathologic changes","up to 3,887 cases, up to 1,027 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2883,{"v":2e-62,"d":"2.00E-62"},61.698970004336,"(Primary)",1.6136,"[1.42-1.8] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-62,"d":"2.00E-62"},61.698970004336,"(S100A13)",0.82494706,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":4e-62,"d":"4.00E-62"},61.397940008672,null,0.3,"[0.24-0.36] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":9e-62,"d":"9.00E-62"},61.0457574905606,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":3e-61,"d":"3.00E-61"},60.5228787452803,"(Free cholesterol in large LDL, conditioned)",0.5335034,"[0.47-0.60] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[30,"rs174564",11,61592362,"rs174566","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174566-G","rs174566",0,174566,"intron_variant",0,"NR",{"v":4e-61,"d":"4.00E-61"},60.397940008672,"(Phosphatidylcholine with diacyl residue sum C36:3/Phosphatidylcholine with diacyl residue sum C38:5)",0.690358,"[0.61-0.77] unit increase","Illumina [up to 9281895] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.709,{"v":5e-61,"d":"5.00E-61"},60.3010299956639,"(Hispanic)",0.226,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":7e-61,"d":"7.00E-61"},60.1549019599857,null,0.099,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":1e-60,"d":"1.00E-60"},60,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61592362,"rs174566","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174566-G","rs174566",0,174566,"intron_variant",0,"NR",{"v":1e-60,"d":"1.00E-60"},60,"(Phosphatidylcholine with diacyl residue sum C36:3/Phosphatidylcholine with diacyl residue sum C38:4)",0.69013,"[0.61-0.77] unit increase","Illumina [up to 9281895] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19q13.32","APOC2, APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.2,{"v":1e-60,"d":"1.00E-60"},60,null,0.19,"[0.15-0.23] unit increase","Affymetrix [389878]","N"]
[26,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":2e-60,"d":"2.00E-60"},59.698970004336,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5028,{"v":2e-60,"d":"2.00E-60"},59.698970004336,null,0.0586027,"[0.052-0.066] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"11:61625723_CA_C",11,61639573,"rs174448","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS3","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,"NR",{"v":3e-60,"d":"3.00E-60"},59.5228787452803,null,0.05,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":4e-60,"d":"4.00E-60"},59.397940008672,"(RAC-beta serine/threonine-protein kinase, AKT2.14685.17.3)",0.73,"[0.65-0.81] unit decrease","Affymetrix [10572788] (imputed)","N"]
[13,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,0.592,{"v":6e-60,"d":"6.00E-60"},59.2218487496163,"(EA)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":6e-60,"d":"6.00E-60"},59.2218487496163,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","11q12.2",null,"TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-?","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":8e-60,"d":"8.00E-60"},59.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[33,"rs35350651",12,111973358,"rs597808","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs597808-A","rs597808",0,597808,"intron_variant",0,0.47,{"v":8e-60,"d":"8.00E-60"},59.096910013008,"(AA, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[22,"rs7816447",8,19820433,"rs12679834","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8p21.3",null,"LPL",null,null,"ENSG00000175445",null,null,"rs12679834-?","rs12679834",0,12679834,"intron_variant",0,"NR",{"v":9E-60,"d":"9.00E-60"},59.0457574905606,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs174564",11,61564299,"rs4246215","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","FEN1","FEN1, FADS2",null,null,"ENSG00000168496, ENSG00000134824",null,null,"rs4246215-T","rs4246215",0,4246215,"3_prime_UTR_variant",0,"NR",{"v":9E-60,"d":"9.00E-60"},59.0457574905606,null,0.02,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.234,{"v":9E-60,"d":"9.00E-60"},59.0457574905606,"(East Asian)",0.274,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.72,{"v":9E-60,"d":"9.00E-60"},59.0457574905606,"(HDL)",0.25,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[5,"rs3832016",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2346,{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.112,"[0.098-0.126] unit decrease","NR [8041861] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":2e-59,"d":"2.00E-59"},58.698970004336,"(TG)",0.17,"[0.14-0.20] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":2e-59,"d":"2.00E-59"},58.698970004336,"(HDL.large, fasting)",0.703,"[NR] unit increase","Illumina [335603]","N"]
[46,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,"NR",{"v":3e-59,"d":"3.00E-59"},58.5228787452803,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-59,"d":"4.00E-59"},58.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,0.28,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(ALP)",0.308,"[0.27-0.35] unit decrease","Illumina [561583]","N"]
[46,"rs1065853",19,45415640,"rs445925","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","19q13.32","APOE, APOC1, APOC2","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(BMI unadjusted)",0.568,"[0.5-0.64] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.591,{"v":5e-59,"d":"5.00E-59"},58.3010299956639,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61551927,"rs174536","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","MYRF, FADS1, FADS2, FADS3","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174536-A","rs174536",0,174536,"non_coding_transcript_exon_variant",0,0.673,{"v":5e-59,"d":"5.00E-59"},58.3010299956639,"(Phosphatidylcholine diacyl C36:5)",0.1315,"[0.12-0.15] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[13,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,"NR",{"v":7e-59,"d":"7.00E-59"},58.1549019599857,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-G","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.19,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,null,7.91,"[6.93-8.89] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.952,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,"(Hispanic)",0.574,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-C","rs174546",0,174546,"3_prime_UTR_variant",0,"NR",{"v":1E-58,"d":"1.00E-58"},58,null,0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs2927482",19,45341948,"rs10407439","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","PVRL2","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,17270,7484,"rs10407439-A","rs10407439",0,10407439,"intergenic_variant",1,0.296,{"v":1E-58,"d":"1.00E-58"},58,null,16.138115,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[8,"rs6544366",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,0.674,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(EA)",0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs449647",19,45408564,"rs449647","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",null,"ENSG00000130203",null,null,447,"rs449647-?","rs449647",0,449647,"regulatory_region_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs449647",19,45408564,"rs449647","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","TOMM40",null,"ENSG00000130203",null,null,447,"rs449647-?","rs449647",0,449647,"regulatory_region_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(Cell surface glycoprotein CD200 receptor 2, CD200R1L.8980.19.3)",0.72,"[0.64-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(Apolipoprotein E (isoform E3), APOE.2937.10.2)",0.72,"[0.64-0.8] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-58,"d":"3.00E-58"},57.5228787452803,"(L-LDL-FC)",0.75,"[0.65-0.85] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[5,"rs3832016",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2343,{"v":4e-58,"d":"4.00E-58"},57.397940008672,null,0.0999,"[0.088-0.112] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[8,"rs6544366",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":5e-58,"d":"5.00E-58"},57.3010299956639,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61560081,"rs174538","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","C11orf10","TMEM258",null,null,"ENSG00000134825",null,null,"rs174538-A","rs174538",0,174538,"5_prime_UTR_variant",0,"NR",{"v":5e-58,"d":"5.00E-58"},57.3010299956639,null,0.08,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[30,"rs174564",11,61579463,"rs174554","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174554-A","rs174554",0,174554,"intron_variant",0,"NR",{"v":5e-58,"d":"5.00E-58"},57.3010299956639,null,0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Cigarettes smoked per day (MTAG)","up to 403,928 European ancestry individuals","NA","19q13.2","NR","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-C","rs56113850",0,56113850,"intron_variant",0,0.555,{"v":5e-58,"d":"5.00E-58"},57.3010299956639,null,0.0361686,"[0.032-0.041] unit increase","NR [9732723] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":6e-58,"d":"6.00E-58"},57.2218487496163,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61551356,"rs174535","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","C11orf9","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174535-T","rs174535",0,174535,"synonymous_variant",0,"NR",{"v":6e-58,"d":"6.00E-58"},57.2218487496163,null,0.08,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[33,"rs35350651",12,111865049,"rs7310615","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","SH2B3","SH2B3",null,null,"ENSG00000111252",null,null,"rs7310615-C","rs7310615",0,7310615,"intron_variant",0,0.49,{"v":7e-58,"d":"7.00E-58"},57.1549019599857,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[13,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,0.622,{"v":1e-57,"d":"1.00E-57"},57,"(EA)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,"NR",{"v":1e-57,"d":"1.00E-57"},57,null,0.08,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[30,"rs174564",11,61571478,"rs174550","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,"NR",{"v":1e-57,"d":"1.00E-57"},57,null,0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","1p13.3","CELSR2, PSRC1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.219,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.124,"[0.11-0.14] unit decrease","Affymetrix [7947838] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":2e-57,"d":"2.00E-57"},56.698970004336,"(EA)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.31,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,3.47,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.1052,"[0.092-0.118] unit increase novel","Illumina [6108953] (imputed)","N"]
[13,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,0.616,{"v":3E-57,"d":"3.00E-57"},56.5228787452803,"(EA)",0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs4803748",19,45251156,"rs2965169","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","BCL3","BCL3",null,null,"ENSG00000069399",null,null,"rs2965169-C","rs2965169",0,2965169,"non_coding_transcript_exon_variant",0,0.3883,{"v":3E-57,"d":"3.00E-57"},56.5228787452803,null,15.944032,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-T","rs4299376",0,4299376,"intron_variant",0,0.7278,{"v":4e-57,"d":"4.00E-57"},56.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[13,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,0.615,{"v":4e-57,"d":"4.00E-57"},56.397940008672,"(EA)",0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":6E-57,"d":"6.00E-57"},56.2218487496163,null,4.68,"[4.11-5.25] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1E-56,"d":"1.00E-56"},56,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2014-05-01",24094242,"Li J","2013-10-05","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/24094242","Genome-wide association study on serum alkaline phosphatase levels in a Chinese population.","Serum alkaline phosphatase levels","1,452 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","9q34.2","SURF6, ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-A","rs651007",0,651007,"intergenic_variant",1,0.226,{"v":1E-56,"d":"1.00E-56"},56,null,0.079,"[0.069-0.089] U/L decrease","Affymetrix [658288]","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-56,"d":"1.00E-56"},56,"(Phosphatidylcholine with acyl-alkyl residue sum C36:3/Phosphatidylcholine with acyl-alkyl residue sum C36:5)",0.649031,"[0.57-0.72] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1E-56,"d":"1.00E-56"},56,"(EA)",0.105,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs4939883",18,47158234,"rs9304381","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32682,18486,"rs9304381-T","rs9304381",0,9304381,"intergenic_variant",1,0.8098,{"v":1E-56,"d":"1.00E-56"},56,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[46,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,"NR",{"v":1E-56,"d":"1.00E-56"},56,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45415640,"rs445925","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","19q13.32","APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-T","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.11,{"v":1E-56,"d":"1.00E-56"},56,"(activity)",0.071,"[0.049-0.093] ng/ml decrease","Illumina [796174]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(Trans-ethnic initial)",0.0564,"[0.049-0.063] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(Phosphatidylcholine with acyl-alkyl residue sum C36:3/Phosphatidylcholine with acyl-alkyl residue sum C38:5)",0.639075,"[0.56-0.71] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.226,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(East Asian)",0.269,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.789,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(Trans-ethnic initial)",0.0652,"[0.057-0.074] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.937,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(APOE)",0.795,"[0.7-0.89] unit increase","Illumina [> 1000000] (imputed)","N"]
[46,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.393,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(EA)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":5E-56,"d":"5.00E-56"},55.3010299956639,"(EA)",0.413,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-02-05",25898920,"Korostishevsky M","2015-04-22","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/25898920","Genomics and metabolomics of muscular mass in a community-based sample of UK females.","Blood metabolite levels","3,953 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-56,"d":"6.00E-56"},55.2218487496163,"(Mannose levels)",null,null,"Illumina [2300000]","N"]
[8,"rs6544366",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":7e-56,"d":"7.00E-56"},55.1549019599857,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":8e-56,"d":"8.00E-56"},55.096910013008,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":9e-56,"d":"9.00E-56"},55.0457574905606,"(VLDL.total, whole)",6.384,"[NR] unit decrease","Illumina [335603]","N"]
[33,"rs35350651",12,111932800,"rs7137828","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Systolic blood pressure","approximately 422,000 European ancestry individuals","NA","12q24.12",null,"ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-?","rs7137828",0,7137828,"intron_variant",0,"NR",{"v":9e-56,"d":"9.00E-56"},55.0457574905606,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","TMEM258, FADS1, FADS2, FADS3","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.6789,{"v":1e-55,"d":"1.00E-55"},55,"(Phosphatidylcholine acyl-alkyl C40:4)",0.0681,"[0.06-0.077] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[30,"rs174564",11,61609750,"rs174583","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-C","rs174583",0,174583,"intron_variant",0,"NR",{"v":1e-55,"d":"1.00E-55"},55,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-T","rs174551",0,174551,"5_prime_UTR_variant",0,"NR",{"v":2E-55,"d":"2.00E-55"},54.698970004336,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0,{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(Trans-ethnic initial)",0.121,"[0.11-0.14] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs7246100",19,45436244,"rs7246099","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,1601,9251,"rs7246099-C","rs7246099",0,7246099,"intergenic_variant",1,0.389,{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(Tubulin-specific chaperone A, TBCA.12501.10.3)",0.44,"[0.38-0.5] unit increase","Affymetrix [10572788] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,5.64,"[4.88-6.4] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,0.121,"[NR] unit decrease","NR [NR] (imputed)","N"]
[38,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":3e-55,"d":"3.00E-55"},54.5228787452803,"(HDL-C.by.NMR, fasting)",2.608,"[NR] unit increase","Illumina [335603]","N"]
[30,"rs174564",11,61600342,"rs174574","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174574-A","rs174574",0,174574,"intron_variant",0,"NR",{"v":4E-55,"d":"4.00E-55"},54.397940008672,null,0.08,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[30,"rs2072114",11,61604967,"rs2072113","2019-04-24",30453627,"Marklund M","2018-11-17","Nutrients","www.ncbi.nlm.nih.gov/pubmed/30453627","Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity.","Fatty acid desaturase activity (serum)","1,453 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs2072113-T","rs2072113",0,2072113,"intron_variant",0,0.17,{"v":4E-55,"d":"4.00E-55"},54.397940008672,"(D6D)",null,null,"Illumina [at least 738879] (imputed)","N"]
[30,"rs174564",11,61564299,"rs4246215","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","FEN1","FEN1, FADS2",null,null,"ENSG00000168496, ENSG00000134824",null,null,"rs4246215-T","rs4246215",0,4246215,"3_prime_UTR_variant",0,"NR",{"v":6e-55,"d":"6.00E-55"},54.2218487496163,null,0.08,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[28,"rs10793624",10,46001866,"rs11239541","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","10q11.22",null,"2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239541-?","rs11239541",0,11239541,"intron_variant",0,"NR",{"v":7e-55,"d":"7.00E-55"},54.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":8E-55,"d":"8.00E-55"},54.096910013008,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.237,{"v":9e-55,"d":"9.00E-55"},54.0457574905606,"(East Asian)",0.265,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":2e-54,"d":"2.00E-54"},53.698970004336,null,0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,"NR",{"v":2e-54,"d":"2.00E-54"},53.698970004336,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.9351,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.0881,"[0.077-0.099] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[37,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.118,"[NR] unit decrease","NR [NR] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,null,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.1615,"[0.14-0.18] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-A","rs1041968",0,1041968,"synonymous_variant",0,0.48,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,null,0.095,"[0.083-0.107] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[21,"rs1692821",8,11705448,"rs1692819","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1692819-A","rs1692819",0,1692819,"intron_variant",0,0.292,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,"(Cathepsin B, CTSB.3061.61.2)",0.42,"[0.36-0.48] unit increase","Affymetrix [10572788] (imputed)","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,"NR",{"v":9e-54,"d":"9.00E-54"},53.0457574905606,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1E-53,"d":"1.00E-53"},53,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":1E-53,"d":"1.00E-53"},53,"(HDL.mean.size, fasting)",0.084,"[NR] unit increase","Illumina [335603]","N"]
[46,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,"(females)",3.921738,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-53,"d":"2.00E-53"},52.698970004336,"(APOB.assay, whole)",5.205,"[NR] unit decrease","Illumina [335603]","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,"NR",{"v":3e-53,"d":"3.00E-53"},52.5228787452803,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.12,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(LDL-C)",0.48,"[0.42-0.54] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[13,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,"NR",{"v":4e-53,"d":"4.00E-53"},52.397940008672,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723675,"rs1800588","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":4e-53,"d":"4.00E-53"},52.397940008672,null,0.05965,"[0.052-0.067] unit increase novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.399,{"v":6e-53,"d":"6.00E-53"},52.2218487496163,"(glucose/mannose + 54 other traits)",0.101,"[NR] unit increase","Affymetrix, Illumina [534665]","N"]
[26,"rs2740488",9,107664301,"rs1883025","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.25,{"v":6e-53,"d":"6.00E-53"},52.2218487496163,null,0.067,"[NR] unit decrease","NR [NR] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":8e-53,"d":"8.00E-53"},52.096910013008,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":1E-52,"d":"1.00E-52"},52,"(Granulins)",0.7583,"[0.67-0.85] unit decrease","Affymetrix [509946]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3929,{"v":1E-52,"d":"1.00E-52"},52,null,0.034923363,"[0.03-0.039] unit decrease","Affymetrix [11514936] (imputed)","N"]
[30,"rs174564",11,61588305,"rs174564","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174564-G","rs174564",0,174564,"intron_variant",0,"NR",{"v":1E-52,"d":"1.00E-52"},52,"(Phosphatidylcholine with diacyl residue sum C34:2/Phosphatidylcholine with diacyl residue sum C36:4)",0.645129,"[0.57-0.72] unit increase","Illumina [up to 9281895] (imputed)","N"]
[43,"rs56322906",19,11350488,"rs2278426","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","C19orf80","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-T","rs2278426",0,2278426,"missense_variant",0,0.1249,{"v":1E-52,"d":"1.00E-52"},52,null,0.0756,"[0.066-0.085] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.076340503,{"v":1E-52,"d":"1.00E-52"},52,"(APOB)",0.5368132,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[8,"rs6544366",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":2E-52,"d":"2.00E-52"},51.698970004336,"(EA)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,0.603,{"v":3E-52,"d":"3.00E-52"},51.5228787452803,"(EA)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,"NR",{"v":3E-52,"d":"3.00E-52"},51.5228787452803,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs4803748",19,45242740,"rs2927439","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,13425,8222,"rs2927439-A","rs2927439",0,2927439,"intergenic_variant",1,0.638,{"v":3E-52,"d":"3.00E-52"},51.5228787452803,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.08,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,"NR",{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61579463,"rs174554","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174554-A","rs174554",0,174554,"intron_variant",0,"NR",{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,0.846,{"v":4E-52,"d":"4.00E-52"},51.397940008672,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":6E-52,"d":"6.00E-52"},51.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-C","rs174546",0,174546,"3_prime_UTR_variant",0,"NR",{"v":6E-52,"d":"6.00E-52"},51.2218487496163,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157581",19,45396219,"rs157582","2015-05-14",22005930,"Hollingworth P","2011-10-18","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/22005930","Genome-wide association study of Alzheimer's disease with psychotic symptoms.","Psychosis and Alzheimer's disease","1,039 European ancestry cases with psychosis, 5,659 European ancestry controls, 260 European, African American and Native American ancestry cases with psychosis from 264 families","NA","19q13.32","APOE","TOMM40",{"$nulls":5},"rs157582-?","rs157582",0,157582,"intron_variant",0,0.26,{"v":9e-52,"d":"9.00E-52"},51.0457574905606,null,2.3,"[NR]","Illumina [1847262] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":1E-51,"d":"1.00E-51"},51,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs111784051",19,45389596,"rs7254892","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","NECTIN2, AC011481.2",null,null,"ENSG00000130202, ENSG00000267114",null,null,"rs7254892-A","rs7254892",0,7254892,"intron_variant",0,0.07,{"v":1E-51,"d":"1.00E-51"},51,"(Asian initial, BMI unadjusted)",0.4,"[0.35-0.45] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid AB1-42 levels","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":1E-51,"d":"1.00E-51"},51,null,0.8,"[0.7-0.9] unit decrease","Illumina [8454933] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs6544366",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(EA)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,0.592,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(EA)",0.07,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.785,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(Trans-ethnic initial)",0.0665,"[0.058-0.075] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.26,"[0.22-0.30] unit decrease","Affymetrix [389878]","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs287",8,19866274,"rs765547","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,41504,70351,"rs765547-?","rs765547",0,765547,"regulatory_region_variant",1,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[46,"rs62117206",19,45247627,"rs4803750","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19q13.32","2-APOE, APOC1","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-?","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,"(APOB.assay, whole)",8.495,"[NR] unit decrease","Illumina [335603]","N"]
[42,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":5E-51,"d":"5.00E-51"},50.3010299956639,null,0.247,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58723675,"rs1800588","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.06402,"[0.056-0.072] unit increase novel","Illumina [6108953] (imputed)","N"]
[42,"rs12608026",18,47119579,"rs11082764","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs11082764-?","rs11082764",0,11082764,"3_prime_UTR_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.07838,"[0.068-0.089] unit increase novel","Illumina [6108953] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":6E-51,"d":"6.00E-51"},50.2218487496163,"(Trans-ethnic initial)",0.118,"[0.1-0.13] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,0.738,{"v":7e-51,"d":"7.00E-51"},50.1549019599857,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":8e-51,"d":"8.00E-51"},50.096910013008,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":8e-51,"d":"8.00E-51"},50.096910013008,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.215,{"v":9e-51,"d":"9.00E-51"},50.0457574905606,"(EA)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2740488",9,107665739,"rs2575876","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2575876-A","rs2575876",0,2575876,"intron_variant",0,0.2448,{"v":9e-51,"d":"9.00E-51"},50.0457574905606,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.785,{"v":1E-50,"d":"1.00E-50"},50,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2017-02-19",27488534,"Patel YM","2016-08-03","Cancer Res","www.ncbi.nlm.nih.gov/pubmed/27488534","Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.","nicotine metabolite ratio in current smokers","437 European ancestry individuals, 364 African American individuals, 453 Latino individuals, 674 Japanese American individuals, 311 Native Hawaiian ancestry individuals","NA","19q13.2","CYP2A6","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-T","rs56113850",0,56113850,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.3644,"[0.32-0.41] unit decrease","Illumina [11892802] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2010-07-01",20529992,"Teupser D","2010-06-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20529992","Genetic regulation of serum phytosterol levels and risk of coronary artery disease.","Phytosterol levels","1,495 European ancestry individuals","2,917 European ancestry individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-C","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.322,{"v":2E-50,"d":"2.00E-50"},49.698970004336,"(campesterol)",12,"[NR] % increase","Affymetrix [374370]","N"]
[24,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2E-50,"d":"2.00E-50"},49.698970004336,null,0.056,"[NR] unit decrease","NR [NR] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-08-22",29860282,"Scelsi MA","2018-05-30","Brain","www.ncbi.nlm.nih.gov/pubmed/29860282","Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.","Cortical amyloid beta load","936 European ancestry individuals","NA","19q13.32","APOE4","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,null,{"v":3e-50,"d":"3.00E-50"},49.5228787452803,"(uncorrected for APOE4 status)",null,null,"Illumina [5137218] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-50,"d":"3.00E-50"},49.5228787452803,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":4E-50,"d":"4.00E-50"},49.397940008672,null,0.0573338,"[0.05-0.065] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":5e-50,"d":"5.00E-50"},49.3010299956639,"(KDR)",0.508,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Total cholesterol levels in LDL","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-50,"d":"5.00E-50"},49.3010299956639,null,0.573,"unit decrease","Illumina [15144991] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2018-01-08",29186428,"Tonjes A","2017-11-27","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/29186428","Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin.","Progranulin levels","1,963 European ancestry individuals, 848 Sorbian (founder/genetic isolate) individuals","1800 European ancestry individuals","1p13.3","CELSR2, PSRC1, MYBPHL, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-C","rs660240",0,660240,"3_prime_UTR_variant",0,0.784,{"v":6e-50,"d":"6.00E-50"},49.2218487496163,null,0.169,"unit increase","Affymetrix [2069113] (imputed)","N"]
[28,"rs10793624",10,45982508,"rs11239537","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular volume","172,433 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239537-C","rs11239537",0,11239537,"intron_variant",0,0.3087,{"v":6e-50,"d":"6.00E-50"},49.2218487496163,null,0.05683413,"[0.049-0.064] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[42,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,"NR",{"v":7e-50,"d":"7.00E-50"},49.1549019599857,null,0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-C","rs174546",0,174546,"3_prime_UTR_variant",0,0.668,{"v":9e-50,"d":"9.00E-50"},49.0457574905606,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,{"$nulls":3},"Affymetrix [NR]","N"]
[31,"rs651821",11,116586283,"rs7350481","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-G","rs7350481",0,7350481,"regulatory_region_variant",1,0.43,{"v":1e-49,"d":"1.00E-49"},49,null,0.241,"[0.21-0.27] unit increase","Illumina [561583]","N"]
[31,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs4803748",19,45251156,"rs2965169","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCL3",null,null,"ENSG00000069399",null,null,"rs2965169-?","rs2965169",0,2965169,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":1e-49,"d":"1.00E-49"},49,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.319,{"v":2e-49,"d":"2.00E-49"},48.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","6q25.3","SLC22A3, LPAL2, LPA, PLG","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.065,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,1.31,"[1.27-1.36]","Affymetrix [9149595] (imputed)","N"]
[20,"rs1461729",8,9183358,"rs9987289","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8p23.1","LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,0.124,"[0.1-0.14] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":2e-49,"d":"2.00E-49"},48.698970004336,"(EPHA4)",0.492,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,0.656,{"v":2e-49,"d":"2.00E-49"},48.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,"NR",{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,0.118,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs35348663",7,73023881,"rs12531645","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL, AC005089.1",null,null,"ENSG00000009950, ENSG00000274080",null,null,"rs12531645-?","rs12531645",0,12531645,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,0.1056,"[0.092-0.12] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,0.748,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs4939883",18,47160953,"rs7241918","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.17,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,1.31,"[1.11-1.51] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.785,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(Trans-ethnic initial)",0.062,"[0.053-0.071] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,0.806,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(EA)",0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,"NR",{"v":4e-49,"d":"4.00E-49"},48.397940008672,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57006590,"rs7499892","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","HDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.773,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(Hispanic)",0.243,"[0.21-0.27] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[18,"6:160560880_CATG_C",6,160564476,"rs662138","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-C","rs662138",0,662138,"intron_variant",0,0.83,{"v":5e-49,"d":"5.00E-49"},48.3010299956639,"(isobutyrylcarnitine)",0.077,"[0.067-0.087] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-49,"d":"5.00E-49"},48.3010299956639,"(Phosphatidylcholine with diacyl residue sum C36:3/Lysophosphatidylcholine with acyl residue C20:4)",0.597844,"[0.52-0.67] unit increase","Illumina [up to 9281895] (imputed)","N"]
[30,"rs61897793",11,61595564,"rs968567","2019-04-24",30453627,"Marklund M","2018-11-17","Nutrients","www.ncbi.nlm.nih.gov/pubmed/30453627","Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity.","Fatty acid desaturase activity (serum)","1,453 European ancestry individuals","NA","11q12.2","FADS2, FADS1, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-T","rs968567",0,968567,"5_prime_UTR_variant",0,0.15,{"v":5e-49,"d":"5.00E-49"},48.3010299956639,"(D5D)",null,null,"Illumina [at least 738879] (imputed)","N"]
[30,"rs174564",11,61579463,"rs174554","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174554-A","rs174554",0,174554,"intron_variant",0,0.668,{"v":6E-49,"d":"6.00E-49"},48.2218487496163,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.794,{"v":6E-49,"d":"6.00E-49"},48.2218487496163,"(Hispanic)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.668,{"v":7e-49,"d":"7.00E-49"},48.1549019599857,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61609750,"rs174583","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-C","rs174583",0,174583,"intron_variant",0,"NR",{"v":8e-49,"d":"8.00E-49"},48.096910013008,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.06015,"[0.052-0.068] unit decrease novel","Illumina [6108953] (imputed)","N"]
[15,"rs6908402",6,26239404,"rs9358913","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p22.2","HIST1H1D, HIST1H2AD, HIST1H2AE, HIST1H2BD, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BH, HIST1H2BI, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4G, HIST1H4H","HIST1H1D - HIST1H4F","ENSG00000124575","ENSG00000274618",null,4243,1250,"rs9358913-G","rs9358913",0,9358913,"regulatory_region_variant",1,0.262178,{"v":1e-48,"d":"1.00E-48"},48,"(females)",0.05275,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[24,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":1e-48,"d":"1.00E-48"},48,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2010-09-13",20694148,"Zabaneh D","2010-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20694148","A genome-wide association study of the metabolic syndrome in Indian Asian men.","Metabolic syndrome","2,554 Indian Asian ancestry individuals","2,240 Indian Asian ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.36,{"v":1e-48,"d":"1.00E-48"},48,"(HDL)",0.07,"[0.06-0.08] mmol/l increase","Illumina [308011]","N"]
[30,"rs174564",11,61593816,"rs174568","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174568-T","rs174568",0,174568,"missense_variant",0,0.324,{"v":2e-48,"d":"2.00E-48"},47.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[30,"rs174564",11,61609750,"rs174583","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-C","rs174583",0,174583,"intron_variant",0,0.656,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.987,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Smoking cessation","up to 547,219 European ancestry individuals","NA","19q13.2","NR","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-C","rs56113850",0,56113850,"intron_variant",0,0.567,{"v":2e-48,"d":"2.00E-48"},47.698970004336,null,0.05760633,"[0.05-0.065] unit decrease","NR [~ 10000000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs1692821",8,11710369,"rs1293292","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1293292-G","rs1293292",0,1293292,"intron_variant",0,0.719,{"v":3e-48,"d":"3.00E-48"},47.5228787452803,"(CTSB)",0.395,"[0.34-0.45] unit decrease","Illumina [> 1000000] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,"NR",{"v":3e-48,"d":"3.00E-48"},47.5228787452803,null,0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3e-48,"d":"3.00E-48"},47.5228787452803,"(Il16)",0.7322723,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109821797,"rs4970836","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3425,381,"rs4970836-A","rs4970836",0,4970836,"intergenic_variant",1,0.771,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(Group XIIB secretory phospholipase A2-like protein, PLA2G12B.9380.2.3)",0.42,"[0.36-0.48] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.828,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(East Asian)",0.256,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(females)",3.2052002,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-T","rs174551",0,174551,"5_prime_UTR_variant",0,"NR",{"v":5e-48,"d":"5.00E-48"},47.3010299956639,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":6e-48,"d":"6.00E-48"},47.2218487496163,null,0.106,"[NR] unit increase","NR [NR] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","HDL cholesterol","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":6e-48,"d":"6.00E-48"},47.2218487496163,null,0.07,"[0.060-0.080] mmol/L decrease","Illumina [4642479] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.829,{"v":7e-48,"d":"7.00E-48"},47.1549019599857,"(East Asian)",0.254,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61581450,"rs7394579","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs7394579-G","rs7394579",0,7394579,"intron_variant",0,0.2771,{"v":8e-48,"d":"8.00E-48"},47.096910013008,null,0.0573956,"[0.05-0.065] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS2, FADS1, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-A","rs1535",0,1535,"intron_variant",0,0.6784,{"v":8e-48,"d":"8.00E-48"},47.096910013008,"(Phosphatidylcholine acyl-alkyl C36:3)",0.0687,"[0.059-0.078] unit decrease","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-48,"d":"8.00E-48"},47.096910013008,"(females)",3.1868043,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.821,{"v":9e-48,"d":"9.00E-48"},47.0457574905606,"(East Asian)",0.258,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs6544366",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs78439586",6,160820922,"rs78439586","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","SLC22A3",null,null,"ENSG00000146477",null,null,"rs78439586-A","rs78439586",0,78439586,"intron_variant",0,null,{"v":1e-47,"d":"1.00E-47"},47,null,6.68,"[5.38-7.98] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-T","rs174551",0,174551,"5_prime_UTR_variant",0,0.684,{"v":1e-47,"d":"1.00E-47"},47,"(EA)",0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":1e-47,"d":"1.00E-47"},47,"(EA)",0.092,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.109,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.08,"[0.068-0.092] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","2p21","ABCG8, ABCG5","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.3,{"v":2e-47,"d":"2.00E-47"},46.698970004336,null,2.75,"[2.36-3.14] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.933,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(Phosphatidylcholine with acyl-alkyl residue sum C36:3/Phosphatidylcholine with acyl-alkyl residue sum C36:4)",0.586854,"[0.51-0.66] unit increase","Illumina [up to 9281895] (imputed)","N"]
[38,"rs247617",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.828,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(East Asian)",0.254,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2012-03-14",22331829,"Chasman DI","2012-02-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22331829","Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.","Response to statins (LDL cholesterol change)","6,989 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(baseline LDL-C)",6.2,"[5.42-6.98] mg/dL decrease","Illumina [814418]","N"]
[8,"rs6544366",2,21231524,"rs676210","2013-03-06",23247145,"Makela KM","2012-12-17","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23247145","Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.","LDL (oxidized)","2,080 European ancestry individuals","4,238 European ancestry individuals","2p24.1","apoB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.77,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,null,10.5,"U/L increase","Illumina [2543887] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.413,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Trans-ethnic initial)",0.0515,"[0.044-0.059] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neuritic plaque","up to 4,232 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3155,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Ordinal)",0.9467,"[0.82-1.08] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-04-17",29458411,"Chung J","2018-02-20","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/29458411","Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.","Neuritic plaques or neurofibrillary tangles (pleiotropy)","3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-47,"d":"3.00E-47"},46.5228787452803,{"$nulls":3},"NR [6500000] (imputed)","N"]
[8,"rs6544366",2,21206183,"rs6754295","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,121650,16002,"rs6754295-?","rs6754295",0,6754295,"intergenic_variant",1,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,"(VLDL.small, fasting)",4.127,"[NR] unit decrease","Illumina [335603]","N"]
[20,"rs1461729",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.086,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet distribution width","164,433 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8668,{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.07616955,"[0.066-0.087] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,null,1.5,"[1.28-1.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.628,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,"(Hispanic)",0.184,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neurofibrillary tangles","up to 4,707 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3285,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,"(Ordinal I)",0.6632,"[0.57-0.75] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-47,"d":"6.00E-47"},46.2218487496163,"(females)",3.7354689,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":6e-47,"d":"6.00E-47"},46.2218487496163,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.054,"[NR] unit increase","NR [NR] (imputed)","N"]
[43,"rs142158911",19,11190652,"rs142130958","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,550,9386,"rs142130958-A","rs142130958",0,142130958,"intergenic_variant",1,0.11,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,"(Free cholesterol in large LDL)",0.24,"[0.2-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[44,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.39,{"v":9E-47,"d":"9.00E-47"},46.0457574905606,null,2.84,"[2.45-3.23] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-T","rs651821",0,651821,"5_prime_UTR_variant",0,0.72,{"v":9E-47,"d":"9.00E-47"},46.0457574905606,"(BMI unadjusted)",0.187,"[0.16-0.21] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[13,"rs56912706",5,75003678,"rs2307111","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","5q13.3",null,"POC5",null,null,"ENSG00000152359",null,null,"rs2307111-?","rs2307111",0,2307111,"missense_variant",0,"NR",{"v":1E-46,"d":"1.00E-46"},46,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs115478735",9,136149711,"rs115478735","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO",null,null,"ENSG00000175164",null,null,"rs115478735-T","rs115478735",0,115478735,"intron_variant",0,0.178,{"v":1E-46,"d":"1.00E-46"},46,"(Immunoglobulin superfamily containing leucine-rich repeat protein 2, ISLR2.13124.20.3)",0.45,"[0.39-0.51] unit decrease","Affymetrix [10572788] (imputed)","N"]
[30,"rs174564",11,61623140,"rs174601","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174601-C","rs174601",0,174601,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-46,"d":"1.00E-46"},46,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":1E-46,"d":"1.00E-46"},46,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1E-46,"d":"1.00E-46"},46,"(CRYZL1)",0.7133005,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[15,"rs6908402",6,26239404,"rs9358913","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p22.2","HIST1H1D, HIST1H2AD, HIST1H2AE, HIST1H2BD, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BH, HIST1H2BI, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4G, HIST1H4H","HIST1H1D - HIST1H4F","ENSG00000124575","ENSG00000274618",null,4243,1250,"rs9358913-G","rs9358913",0,9358913,"regulatory_region_variant",1,0.262178,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(females)",0.05168,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":2E-46,"d":"2.00E-46"},45.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.249,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(East Asian)",0.238,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.826,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(East Asian)",0.249,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61543499,"rs174528","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Gondoic acid (20:1n-9) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","11q12.2","FADS1, FADS2","MYRF, TMEM258",null,null,"ENSG00000124920, ENSG00000134825",null,null,"rs174528-C","rs174528",0,174528,"intron_variant",0,0.364,{"v":3e-46,"d":"3.00E-46"},45.5228787452803,"(EA)",0.007,"[0.005-0.009] unit increase","Affymetrix, Illumina [2200000] (imputed)","N"]
[31,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,160997118,"rs74617384","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-A","rs74617384",0,74617384,"intron_variant",0,0.942,{"v":4e-46,"d":"4.00E-46"},45.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (both parents in top 10%)","7,182 cases, 79,767 controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.842,{"v":7e-46,"d":"7.00E-46"},45.1549019599857,null,0.0388,"[0.034-0.044] unit increase","Affymetrix [11535925] (imputed)","N"]
[33,"rs35350651",12,112591686,"rs17630235","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.13","NR","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-G","rs17630235",0,17630235,"intergenic_variant",1,null,{"v":8e-46,"d":"8.00E-46"},45.096910013008,null,0.341,"unit decrease","Affymetrix [at least 2696785] (imputed)","N"]
[8,"rs6544366",2,21225281,"rs1042034","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.22,{"v":1e-45,"d":"1.00E-45"},45,null,5.99,"[5.11-6.87] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[13,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,0.603,{"v":1e-45,"d":"1.00E-45"},45,"(EA)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61623140,"rs174601","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Gondoic acid (20:1n-9) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","11q12.2","FADS2, FADS1","FADS2",null,null,"ENSG00000134824",null,null,"rs174601-T","rs174601",0,174601,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-45,"d":"1.00E-45"},45,null,0.007,"[0.005-0.009] unit increase","Affymetrix, Illumina [2200000] (imputed)","N"]
[13,"rs4704210",5,74639259,"rs3843482","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-G","rs3843482",0,3843482,"intron_variant",0,0.38,{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.087,"[0.075-0.099] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[20,"rs1461729",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112059557,"rs11065979","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","BRAP","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.45,{"v":2E-45,"d":"2.00E-45"},44.698970004336,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs11882123",19,19475088,"rs2965199","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,5524,21547,"rs2965199-?","rs2965199",0,2965199,"intergenic_variant",1,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p21","ABCG8, ABCG5","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.3,{"v":4e-45,"d":"4.00E-45"},44.397940008672,null,3.01,"[2.58-3.44] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[18,"rs6938647",6,160991798,"rs6903649","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs6903649-C","rs6903649",0,6903649,"intron_variant",0,null,{"v":4e-45,"d":"4.00E-45"},44.397940008672,null,2.6,"[1.95-3.25] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[13,"rs4704210",5,74656539,"rs12916","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.39,{"v":5e-45,"d":"5.00E-45"},44.3010299956639,null,2.45,"[2.1-2.8] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-A","rs1535",0,1535,"intron_variant",0,0.637,{"v":5e-45,"d":"5.00E-45"},44.3010299956639,"(Trans-ethnic initial)",0.0529,"[0.045-0.06] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[46,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,"NR",{"v":5e-45,"d":"5.00E-45"},44.3010299956639,null,0.166,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs7970695",12,121424861,"rs7310409","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","12q24.31","C12orf27, HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.59,{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,6.8,"[5.70-7.80] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[42,"rs4939883",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,"NR",{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":7E-45,"d":"7.00E-45"},44.1549019599857,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",1.5,"[1.28-1.72] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":8e-45,"d":"8.00E-45"},44.096910013008,null,0.020889835,"[0.018-0.024] unit increase","NR [~ 10000000] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,0.643,{"v":8e-45,"d":"8.00E-45"},44.096910013008,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.793,{"v":8e-45,"d":"8.00E-45"},44.096910013008,"(Hispanic)",0.214,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":9e-45,"d":"9.00E-45"},44.0457574905606,null,0.05407684,"[0.047-0.062] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-03-15",23263486,"Kottgen A","2012-12-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23263486","Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.","Urate levels","49,825 European ancestry males, 60,522 European ancestry females","Up to 32,813 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-44,"d":"1.00E-44"},44,null,0.074,"[0.063-0.084] mg/dl increase","Affymetrix, Illumina, Perlegen [2450547] (imputed)","N"]
[28,"rs10793624",10,45982508,"rs11239537","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239537-C","rs11239537",0,11239537,"intron_variant",0,0.3088,{"v":1e-44,"d":"1.00E-44"},44,null,0.0538346,"[0.046-0.061] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs247617",16,56990716,"rs247617","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-A","rs247617",0,247617,"regulatory_region_variant",1,0.262,{"v":1e-44,"d":"1.00E-44"},44,"(AA)",0.0619,"[NR] unit increase","Affymetrix [NR]","N"]
[42,"rs4939883",18,47160953,"rs7241918","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.19,{"v":1e-44,"d":"1.00E-44"},44,null,0.09,"[NR] unit decrease","NR [NR] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-44,"d":"1.00E-44"},44,null,0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.01,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.47,"[0.41-0.53] unit decrease","Affymetrix [389878]","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":2e-44,"d":"2.00E-44"},43.698970004336,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,29206683,"rs3130820","2018-12-17",29483656,"Pardinas AF","2018-02-26","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29483656","Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.","Schizophrenia","40,675 European ancestry cases, 64,643 European ancestry controls","1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls","6p22.1","xMHC","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130820-?","rs3130820",0,3130820,"intron_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,1.281,"[1.25-1.32]","Illumina [8000000] (imputed)","N"]
[22,"rs287",8,19852045,"rs17489268","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27275,84580,"rs17489268-A","rs17489268",0,17489268,"regulatory_region_variant",1,0.2874,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,3.514711,"[3.02-4.01] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[22,"rs287",8,19866274,"rs765547","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,41504,70351,"rs765547-?","rs765547",0,765547,"regulatory_region_variant",1,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[31,"rs180327",11,116624703,"rs180326","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs180326-C","rs180326",0,180326,"intron_variant",0,0.22,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.06,"[0.05-0.06] unit increase","Illumina [4642479] (imputed)","N"]
[31,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2018-04-26",25751624,"Onengut-Gumuscu S","2015-04-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25751624","Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.","Type 1 diabetes","6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios","NA","12q24.12","SH2B3","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-C","rs653178",0,653178,"intron_variant",0,0.48,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,1.3,null,"Illumina [135870]","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0793,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.08988161,"[0.077-0.102] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2009-09-28",17998437,"Li H","2007-11-12","Arch Neurol","www.ncbi.nlm.nih.gov/pubmed/17998437","Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.","Alzheimer's disease","753 European ancestry cases, 736 European ancestry controls","418 European ancestry cases, 249 European ancestry controls","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,{"$nulls":3},"Affymetrix [469438]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.0187927,"[0.016-0.021] unit increase","NR [~ 9732723] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1461729",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","TMEM258, FADS1, FADS2, FADS3","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.6785,{"v":3e-44,"d":"3.00E-44"},43.5228787452803,"(Phosphatidylcholine acyl-alkyl C40:5)",0.0605,"[0.052-0.069] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[30,"rs174564",11,61592362,"rs174566","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174566-G","rs174566",0,174566,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,"(Lysophosphatidylcholine with acyl residue C18:1/Lysophosphatidylcholine with acyl residue C20:4)",0.587293,"[0.51-0.67] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","11q23.3",null,"ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":4e-44,"d":"4.00E-44"},43.397940008672,"(Insulin receptor)",0.6958,"[0.6-0.79] unit decrease","Affymetrix [509946]","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61581656,"rs174559","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","11q12.2","MIR1908","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174559-A","rs174559",0,174559,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-44,"d":"5.00E-44"},43.3010299956639,null,0.0588124,"[0.05-0.067] unit decrease","Affymetrix [16832071] (imputed)","N"]
[31,"rs5072",11,116703640,"rs5128","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","NR","APOC3",null,null,"ENSG00000110245",null,null,"rs5128-C","rs5128",0,5128,"3_prime_UTR_variant",0,0.916,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(Beta-endorphin, POMC.2558.51.3)",0.6,"[0.52-0.68] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neurofibrillary tangles","up to 4,707 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3219,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(Ordinal II)",0.7871,"[0.68-0.9] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":6e-44,"d":"6.00E-44"},43.2218487496163,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2015-06-08",25350695,"Postmus I","2014-10-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25350695","Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.","Response to statins (LDL cholesterol change)","18,596 European ancestry individuals","23,279 European ancestry individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.087,{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.052,"[0.044-0.060] unit increase","Affymetrix, Illumina, Perlegen [at least 2500000] (imputed)","N"]
[46,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":7e-44,"d":"7.00E-44"},43.1549019599857,"(Valine--tRNA ligase, VARS.13083.18.3)",1.48,"[1.26-1.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-43,"d":"1.00E-43"},43,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1461729",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs13284054",9,107657070,"rs3905000","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-G","rs3905000",0,3905000,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.786,{"v":1e-43,"d":"1.00E-43"},43,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-A","rs1535",0,1535,"intron_variant",0,0.637,{"v":1e-43,"d":"1.00E-43"},43,"(Trans-ethnic initial)",0.0497,"[0.042-0.057] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Monocyte count","170,721 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5169,{"v":1e-43,"d":"1.00E-43"},43,null,0.04937698,"[0.042-0.056] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs4803748",19,45242740,"rs2927439","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,13425,8222,"rs2927439-A","rs2927439",0,2927439,"intergenic_variant",1,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74637711,"rs10038095","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-T","rs10038095",0,10038095,"intron_variant",0,0.38,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,0.083,"[0.071-0.095] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":4e-43,"d":"4.00E-43"},42.397940008672,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-43,"d":"6.00E-43"},42.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,null,0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":9e-43,"d":"9.00E-43"},42.0457574905606,null,4.94,"[4.16-5.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.21,{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.23,"[0.19-0.27] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[30,"rs174564",11,61588305,"rs174564","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174564-G","rs174564",0,174564,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,"(Lysophosphatidylcholine with acyl residue C16:0/Lysophosphatidylcholine with acyl residue C20:4)",0.575391,"[0.5-0.65] unit increase","Illumina [up to 9281895] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-42,"d":"3.00E-42"},41.5228787452803,null,0.051,"[NR] unit increase","NR [NR] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs673548-?","rs673548",0,673548,"intron_variant",0,"NR",{"v":5E-42,"d":"5.00E-42"},41.3010299956639,"(VLDL.total, fasting)",6.624,"[NR] unit decrease","Illumina [335603]","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid AB1-42 levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":6e-42,"d":"6.00E-42"},41.2218487496163,{"$nulls":3},"Illumina [563980]","N"]
[24,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":7e-42,"d":"7.00E-42"},41.1549019599857,null,0.05782,"[0.049-0.066] unit decrease novel","Illumina [6108953] (imputed)","N"]
[46,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,0.964,{"v":1E-41,"d":"1.00E-41"},41,"(EA)",0.167,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","TMEM258, FADS1, FADS2, FADS3","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.6734,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(Phosphatidylcholine acyl-alkyl C44:6)",0.0693,"[0.059-0.079] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":3e-41,"d":"3.00E-41"},40.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-C","rs174546",0,174546,"3_prime_UTR_variant",0,0.668,{"v":4E-41,"d":"4.00E-41"},40.397940008672,"(EA)",0.059,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":7e-41,"d":"7.00E-41"},40.1549019599857,null,0.101,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs34121855",7,72999105,"rs9638182","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.81,{"v":1e-40,"d":"1.00E-40"},40,null,0.1,"[0.084-0.116] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2009-02-25",19125160,"Feulner TM","2009-01-07","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/19125160","Examination of the current top candidate genes for AD in a genome-wide association study.","Alzheimer's disease","491 European ancestry cases, 479 European ancestry controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":1e-40,"d":"1.00E-40"},40,{"$nulls":3},"Illumina [~ 550000]","N"]
[27,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":3e-40,"d":"3.00E-40"},39.5228787452803,"(Intercellular adhesion molecule 5, ICAM5.8245.27.3)",0.42,"[0.36-0.48] unit decrease","Affymetrix [10572788] (imputed)","N"]
[33,"rs35350651",12,112273499,"rs11513729","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","MAPKAPK5-AS1","ALDH2 - MAPKAPK5-AS1","ENSG00000111275","ENSG00000234608",null,18166,4069,"rs11513729-T","rs11513729",0,11513729,"intergenic_variant",1,0.4,{"v":8e-40,"d":"8.00E-40"},39.096910013008,"(AA, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[20,"rs1461729",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"NR [2501543] (imputed)","N"]
[31,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.355,{"v":1e-39,"d":"1.00E-39"},39,"(Hispanic)",0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,"(females)",3.1072497,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.36,{"v":2e-39,"d":"2.00E-39"},38.698970004336,null,0.051,"[NR] unit decrease","NR [NR] (imputed)","N"]
[31,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0799,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,null,0.1603,"[0.14-0.18] unit decrease","NR [8041861] (imputed)","N"]
[33,"rs35350651",12,112200150,"rs2013002","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ALDH2","AC002996.1",null,null,"ENSG00000257767",null,null,"rs2013002-T","rs2013002",0,2013002,"intron_variant",0,0.44,{"v":4e-39,"d":"4.00E-39"},38.397940008672,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[20,"rs1461729",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.053,"[0.045-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs7816447",8,19847690,"rs10503669","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-T","rs10503669",0,10503669,"intergenic_variant",1,0.12,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.0857,"[0.073-0.098] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":1e-38,"d":"1.00E-38"},38,null,0.08,"[0.068-0.092] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[30,"rs174564",11,61588305,"rs174564","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174564-G","rs174564",0,174564,"intron_variant",0,"NR",{"v":2e-38,"d":"2.00E-38"},37.698970004336,"(Phosphatidylcholine with diacyl residue sum C32:2/Phosphatidylcholine with diacyl residue sum C34:4)",0.553333,"[0.47-0.63] unit increase","Illumina [up to 9281895] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Dementia and core Alzheimer's disease neuropathologic changes","up to 3,887 cases, up to 1,027 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2864,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,"(Complete)",1.501,"[1.27-1.73] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,null,0.08416118,"[0.071-0.097] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":8e-38,"d":"8.00E-38"},37.096910013008,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,"(TG.assay, whole)",0.07,"[NR] unit increase","Illumina [335603]","N"]
[24,"rs2954021",8,126485294,"rs2954027","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954027-A","rs2954027",0,2954027,"intron_variant",0,0.4663,{"v":2e-37,"d":"2.00E-37"},36.698970004336,null,0.04543718,"[0.038-0.052] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[42,"rs4939883",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.164,{"v":2e-37,"d":"2.00E-37"},36.698970004336,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":4e-37,"d":"4.00E-37"},36.397940008672,"(EA)",0.151,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569306,"rs174545","2016-10-12",26584805,"Dorajoo R","2015-11-19","Genes Nutr","www.ncbi.nlm.nih.gov/pubmed/26584805","A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.","Delta-6 desaturase activity","717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls","NA","11q12.2","NR","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174545-G","rs174545",0,174545,"3_prime_UTR_variant",0,0.6561,{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.2367,"[0.20-0.27] unit decrease","Illumina [up to 1980188] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.897,{"v":1e-36,"d":"1.00E-36"},36,"(Asian initial, BMI unadjusted)",0.163,"[0.14-0.19] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":1e-36,"d":"1.00E-36"},36,null,0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11188153,"rs55791371","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs55791371-A","rs55791371",0,55791371,"intron_variant",0,0.8868,{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,{"v":0.1157,"d":"1.16E-01"},"[0.098-0.134] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[13,"rs4704210",5,74909972,"rs11748027","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","5q13.3","ANKDD1B","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs11748027-?","rs11748027",0,11748027,"intron_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.05115,"[0.043-0.059] unit increase novel","Illumina [6108953] (imputed)","N"]
[31,"rs35120633",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,0.674,{"v":3e-36,"d":"3.00E-36"},35.5228787452803,"(EA)",0.062,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs13284054",9,107657070,"rs3905000","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-G","rs3905000",0,3905000,"intron_variant",0,0.86,{"v":4e-36,"d":"4.00E-36"},35.397940008672,"(EA)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-36,"d":"6.00E-36"},35.2218487496163,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs4939883",18,47158186,"rs10438978","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-C","rs10438978",0,10438978,"intergenic_variant",1,0.81,{"v":8e-36,"d":"8.00E-36"},35.096910013008,null,0.095,"[0.079-0.111] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[13,"rs253412",5,74971846,"rs34361","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","POC5",null,null,"ENSG00000152359",null,null,"rs34361-A","rs34361",0,34361,"intron_variant",0,"NR",{"v":9e-36,"d":"9.00E-36"},35.0457574905606,null,0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":1E-35,"d":"1.00E-35"},35,null,0.13,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[10,"rs11887534",2,44079310,"rs72875462","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs72875462-C","rs72875462",0,72875462,"intron_variant",0,0.93,{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.148,"[0.12-0.17] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.121,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(Hispanic)",0.261,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.079,{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.1368,"[0.12-0.16] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(Phosphatidylcholine with diacyl residue sum C36:4/Phosphatidylcholine with acyl-alkyl residue sum C36:3)",0.523961,"[0.44-0.6] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[9,"rs1728918",2,27635463,"rs1728918","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":5e-35,"d":"5.00E-35"},34.3010299956639,{"$nulls":3},"Affymetrix [NR]","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":6e-35,"d":"6.00E-35"},34.2218487496163,"(Selenoprotein S, VIMP.11286.78.3)",0.41,"[0.35-0.47] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-35,"d":"8.00E-35"},34.096910013008,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":1e-34,"d":"1.00E-34"},34,"(EA)",0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.1,{"v":2e-34,"d":"2.00E-34"},33.698970004336,null,0.23,"[0.17-0.29] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[51,"rs2179372",20,39724338,"rs6065311","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","20q12","MAFB","TOP1",null,null,"ENSG00000198900",null,null,"rs6065311-T","rs6065311",0,6065311,"intron_variant",0,0.54,{"v":2e-34,"d":"2.00E-34"},33.698970004336,"(Trans-ethnic initial)",0.0417,"[0.035-0.049] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[51,"rs2179372",20,39724338,"rs6065311","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6065311-T","rs6065311",0,6065311,"intron_variant",0,0.54,{"v":2e-34,"d":"2.00E-34"},33.698970004336,"(Trans-ethnic initial)",0.0417,"[0.035-0.049] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":3E-34,"d":"3.00E-34"},33.5228787452803,"(Estrogen sulfotransferase, SULT1E1.9878.3.3)",0.4,"[0.34-0.46] unit decrease","Affymetrix [10572788] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.68,{"v":6E-34,"d":"6.00E-34"},33.2218487496163,null,0.077,"[0.065-0.089] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":7e-34,"d":"7.00E-34"},33.1549019599857,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs34232196",1,55487346,"rs12117661","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","BSND - PCSK9","ENSG00000162399","ENSG00000169174",null,9889,17875,"rs12117661-C","rs12117661",0,12117661,"regulatory_region_variant",1,"NR",{"v":1e-33,"d":"1.00E-33"},33,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,"NR",{"v":1e-33,"d":"1.00E-33"},33,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.25,{"v":2e-33,"d":"2.00E-33"},32.698970004336,null,0.94,"[0.76-1.12] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,"(Hepatocyte growth factor receptor, MET.2837.3.2)",0.38,"[0.32-0.44] unit decrease","Affymetrix [10572788] (imputed)","N"]
[30,"rs174564",11,61581450,"rs7394579","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean platelet volume","164,454 European ancestry individuals","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs7394579-G","rs7394579",0,7394579,"intron_variant",0,0.278,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,null,0.04847727,"[0.041-0.056] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs117427818",16,57010486,"rs117427818","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs117427818-T","rs117427818",0,117427818,"intron_variant",0,0.05,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,null,0.46,"[0.39-0.53] µg/mL increase","Illumina [NR] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal P-tau181p levels","3,146 individuals","NA","19q13.32","APOE, TOMM40, PVRL2, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":5e-33,"d":"5.00E-33"},32.3010299956639,null,0.079,"[0.067-0.091] unit increase","Illumina [7358575] (imputed)","N"]
[52,"rs372038686",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,"NR",{"v":7e-33,"d":"7.00E-33"},32.1549019599857,null,0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs11887534",2,44066247,"rs11887534","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-C","rs11887534",0,11887534,"missense_variant",0,"NR",{"v":9e-33,"d":"9.00E-33"},32.0457574905606,{"$nulls":3},"NR [2501749] (imputed)","N"]
[46,"rs375972689",19,45360488,"rs375972689","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs375972689-?","rs375972689",0,375972689,"intron_variant",0,"NR",{"v":1e-32,"d":"1.00E-32"},32,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[21,"rs11250098",8,11078949,"rs2409749","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","intergenic","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,17769,26186,"rs2409749-A","rs2409749",0,2409749,"regulatory_region_variant",1,0.51151,{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,11.865,"z score increase","Illumina [18485882] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.181,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(Trans-ethnic initial)",0.0555,"[0.046-0.065] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[43,"rs576249617",19,11227602,"rs688","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs688-C","rs688",0,688,"synonymous_variant",0,"NR",{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,0.057,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,null,0.049,"[NR] unit decrease","NR [NR] (imputed)","N"]
[44,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.934,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,"(EA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.39,{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,8.59,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[30,"rs174564",11,61592362,"rs174566","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174566-G","rs174566",0,174566,"intron_variant",0,"NR",{"v":6e-32,"d":"6.00E-32"},31.2218487496163,"(Phosphatidylcholine with diacyl residue sum C34:3/Phosphatidylcholine with diacyl residue sum C34:4)",0.504805,"[0.42-0.59] unit increase","Illumina [up to 9281895] (imputed)","N"]
[33,"rs35350651",12,111973358,"rs597808","2018-10-18",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption interaction (2df test)","63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers,  2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs597808-A","rs597808",0,597808,"intron_variant",0,0.49,{"v":8e-32,"d":"8.00E-32"},31.096910013008,"(EA, Hispanic)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63094207,"rs11485618","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11485618-A","rs11485618",0,11485618,"3_prime_UTR_variant",0,0.691,{"v":1e-31,"d":"1.00E-31"},31,"(Trans-ethnic initial)",0.05,"[0.042-0.058] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[24,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":1e-31,"d":"1.00E-31"},31,"(Vascular endothelial growth factor receptor 3)",0.5933,"[0.5-0.69] unit decrease","Affymetrix [509946]","N"]
[18,"rs10455872",6,161010118,"rs10455872","2018-05-02",29511194,"Helgadottir A","2018-03-07","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29511194","Genome-wide analysis yields new loci associating with aortic valve stenosis.","Aortic valve stenosis","2,457 Icelandic ancestry cases, 349,342 Icelandic ancestry controls (including non-array genotyped, whole genome imputed individuals)","4,850 European ancestry cases, 451,731 European ancestry controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.062,{"v":2e-31,"d":"2.00E-31"},30.698970004336,null,1.46,"[1.37-1.56]","Illumina [32500000] (imputed)","N"]
[14,"rs6882345",5,156390297,"rs6882076","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.36,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,null,0.046,"[NR] unit decrease","NR [NR] (imputed)","N"]
[38,"rs193695",16,56985139,"rs9989419","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-G","rs9989419",0,9989419,"regulatory_region_variant",1,0.65,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,null,1.72,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(males)",3.8628085,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,{"v":4e-31,"d":"4.00E-31"},30.397940008672,null,0.05,"[NR] unit increase","NR [NR] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":5e-31,"d":"5.00E-31"},30.3010299956639,"(EA)",0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61606642,"rs174580","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174580-G","rs174580",0,174580,"intron_variant",0,"NR",{"v":9e-31,"d":"9.00E-31"},30.0457574905606,"(Phosphatidylcholine with diacyl residue sum C36:2/Phosphatidylcholine with acyl-alkyl residue sum C38:5)",0.486578,"[0.41-0.57] unit increase","Illumina [up to 9281895] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1e-30,"d":"1.00E-30"},30,"(ENG)",0.394,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","Triglyceride levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","11q23.3","BUD13, APOA5, ZNF259, APOA4, APOC3, APOA1, KIAA0999, LOC645044APOA1","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-G","rs651821",0,651821,"5_prime_UTR_variant",0,null,{"v":1e-30,"d":"1.00E-30"},30,"(Japanese)",0.32,"[0.27-0.37] unit increase","Illumina [1294241]","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(EA)",0.133,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(Phosphatidylcholine with acyl-alkyl residue sum C36:2/Phosphatidylcholine with acyl-alkyl residue sum C38:4)",0.48109,"[0.4-0.56] unit increase","Illumina [up to 9281895] (imputed)","N"]
[34,"rs11065358",12,121416650,"rs1169288","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","12q24.31","HNF1A","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.6937,{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.0344,"[0.029-0.04] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.12,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(TC)",0.09,"[0.070-0.110] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,0.738,{"v":4e-30,"d":"4.00E-30"},29.397940008672,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2409784",8,11433780,"rs2409797","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","intergenic","AC022239.1 - LINC00208","ENSG00000269954","ENSG00000170983",null,11577,42,"rs2409797-T","rs2409797",0,2409797,"intergenic_variant",1,0.46977,{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,11.393,"z score decrease","Illumina [18485882] (imputed)","N"]
[31,"rs6589567",11,116670676,"rs6589567","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","11q23.3","ZPR1, APOA5, APOA4","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,7540,13244,"rs6589567-T","rs6589567",0,6589567,"intergenic_variant",1,0.1178,{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,8.971131,"[7.43-10.52] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2011-11-16",22003152,"Grallert H","2011-10-14","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/22003152","Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.","Lipoprotein-associated phospholipase A2 activity and mass","12,126 European ancestry individuals, 1,538 individuals","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.84,{"v":5e-30,"d":"5.00E-30"},29.3010299956639,"(Activity concentrations)",0.054,"[0.044-0.064] unit decrease","Affymetrix, Illumina [2661766] (imputed)","N"]
[30,"rs174564",11,61585144,"rs174562","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174562-G","rs174562",0,174562,"intron_variant",0,"NR",{"v":7e-30,"d":"7.00E-30"},29.1549019599857,"(Phosphatidylcholine with diacyl residue sum C36:3/Phosphatidylcholine with acyl-alkyl residue sum C40:1)",0.496589,"[0.41-0.58] unit increase","Illumina [up to 9281895] (imputed)","N"]
[24,"rs112875651",8,126500031,"rs28601761","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.416,{"v":8e-30,"d":"8.00E-30"},29.096910013008,null,0.063,"[0.051-0.075] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[52,"rs372038686",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,"NR",{"v":8e-30,"d":"8.00E-30"},29.096910013008,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,29206683,"rs150817755","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","6p22.1","OR2G1P","AL672167.1",null,null,"ENSG00000197171",null,null,"rs150817755-T","rs150817755",1,3130820,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,"(EA)",1.261,"[1.22-1.3]","Illumina [6627481] (imputed)","N"]
[30,"rs174564",11,61588305,"rs174564","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174564-G","rs174564",0,174564,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,"(Phosphatidylcholine with diacyl residue sum C36:4/Phosphatidylcholine with acyl-alkyl residue sum C36:2)",0.477627,"[0.4-0.56] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[14,"rs6882345",5,156398169,"rs1501908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,"(TG.by.NMR, fasting)",0.056,"[NR] unit increase","Illumina [335603]","N"]
[21,"rs2409784",8,11433780,"rs2409797","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Neuroticism","523,783 European ancestry individuals","59,206 European ancestry individuals","8p23.1","NR","AC022239.1 - LINC00208","ENSG00000269954","ENSG00000170983",null,11577,42,"rs2409797-C","rs2409797",0,2409797,"intergenic_variant",1,0.540638682420715,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.020931683,"[0.017-0.025] unit increase","NR [NR]","N"]
[30,"rs174564",11,61581368,"rs174557","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174557-G","rs174557",0,174557,"intron_variant",0,"NR",{"v":4e-29,"d":"4.00E-29"},28.397940008672,"(Phosphatidylcholine with diacyl residue sum C36:4/Lysophosphatidylcholine with acyl residue C20:3)",0.49858,"[0.41-0.58] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal T-tau levels","3,146 individuals","NA","19q13.32","APOE, APOC1, TOMM40, PVRL2","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":4e-29,"d":"4.00E-29"},28.397940008672,null,0.078,"[0.064-0.092] unit increase","Illumina [7358575] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":7e-29,"d":"7.00E-29"},28.1549019599857,null,0.1276141,"[NR] unit decrease","Illumina [575353]","N"]
[44,"rs58542926",19,19379549,"rs58542926","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.11","CILP2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.92,{"v":8e-29,"d":"8.00E-29"},28.096910013008,null,0.122,"[0.1-0.14] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs1065853",19,45415640,"rs445925","2015-06-08",25350695,"Postmus I","2014-10-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25350695","Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.","Response to statins (LDL cholesterol change)","18,596 European ancestry individuals","23,279 European ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.157,{"v":9e-29,"d":"9.00E-29"},28.0457574905606,null,0.051,"[0.041-0.061] unit decrease","Affymetrix, Illumina, Perlegen [at least 2500000] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1e-28,"d":"1.00E-28"},28,"(ISLR2)",0.387,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-?","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.1122,"[0.092-0.132] unit increase novel","Illumina [6108953] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":2e-28,"d":"2.00E-28"},27.698970004336,"(KIN)",0.376,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[30,"rs174564",11,61588305,"rs174564","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174564-G","rs174564",0,174564,"intron_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,"(Phosphatidylcholine with diacyl residue sum C38:5/Phosphatidylcholine with acyl-alkyl residue sum C36:2)",0.474674,"[0.39-0.56] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[52,"rs372038686",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61581764,"rs174560","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174560-C","rs174560",0,174560,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-28,"d":"4.00E-28"},27.397940008672,"(Phosphatidylcholine with diacyl residue sum C38:4/Lysophosphatidylcholine with acyl residue C20:3)",0.481575,"[0.4-0.57] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[37,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.36,{"v":8e-28,"d":"8.00E-28"},27.096910013008,null,0.039,"[NR] unit decrease","NR [NR] (imputed)","N"]
[10,"rs11887534",2,44079310,"rs72875462","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs72875462-C","rs72875462",0,72875462,"intron_variant",0,0.933,{"v":1E-27,"d":"1.00E-27"},27,"(EA)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs62117206",19,45247627,"rs4803750","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19q13.32","2-APOE, APOC1","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-?","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":1E-27,"d":"1.00E-27"},27,"(LDL-C.assay, fasting)",9.276,"[NR] unit decrease","Illumina [335603]","N"]
[46,"rs429358",19,45411941,"rs429358","2017-11-27",29030599,"Joshi PK","2017-10-13","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29030599","Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.","Parental lifespan","up to 586,626 European ancestry individuals, up to 19,433 African ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.142,{"v":1E-27,"d":"1.00E-27"},27,"(EA)",0.9,"years decrease","Affymetrix, Illumina [at least 13643373] (imputed)","N"]
[28,"rs148063610",10,45958856,"rs2291428","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","10q11.21","2008-03-01","2008-03-01",null,null,"ENSG00000165406",null,null,"rs2291428-?","rs2291428",0,2291428,"missense_variant",0,null,{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,1.12,"[1.10-1.15]","Affymetrix, Illumina [43000000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease","10,874 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06071,{"v":2e-27,"d":"2.00E-27"},26.698970004336,null,0.04,"[-1.5672-1.6472] unit decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[10,"rs11887534",2,44074000,"rs4953023","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4953023-G","rs4953023",0,4953023,"non_coding_transcript_exon_variant",0,0.932,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(EA)",0.099,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.25,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,2.24,"[1.77-2.71] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[44,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,0.927,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.861,{"v":4e-27,"d":"4.00E-27"},26.397940008672,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau:AB1-42 ratio","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":4e-27,"d":"4.00E-27"},26.397940008672,{"$nulls":3},"Illumina [563980]","N"]
[5,"rs3832016",1,109818530,"rs646776","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-27,"d":"5.00E-27"},26.3010299956639,null,0.08159,"[0.067-0.096] unit increase novel","Illumina [6108953] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal AB1-42 levels in mild cognitive impairment","581 European ancestry MCI dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":6e-27,"d":"6.00E-27"},26.2218487496163,null,0.77,"[0.63-0.91] unit decrease","Illumina [8448490] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-27,"d":"7.00E-27"},26.1549019599857,"(Phosphatidylcholine with diacyl residue sum C34:1/Phosphatidylcholine with diacyl residue sum C38:4)",0.462963,"[0.38-0.55] unit increase","Illumina [up to 9281895] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-A","rs660240",0,660240,"3_prime_UTR_variant",0,0.21,{"v":1E-26,"d":"1.00E-26"},26,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-T","rs174551",0,174551,"5_prime_UTR_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111910219,"rs10774625","2017-05-11",27182965,"Pickrell JK","2016-05-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27182965","Detection and interpretation of shared genetic influences on 42 human traits.","Hypothyroidism","17,558 European ancestry cases, 117,083 European ancestry controls","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs10774625-?","rs10774625",0,10774625,"intron_variant",0,"NR",{"v":1E-26,"d":"1.00E-26"},26,null,1.1428571,"[1.11-1.17]","Illumina [13676411] (imputed)","N"]
[14,"rs6882345",5,156390297,"rs6882076","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.367,{"v":2e-26,"d":"2.00E-26"},25.698970004336,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Total cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.063,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,13.1251,"[10.72-15.53] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[16,"rs1233489",6,28667669,"rs116137698","2017-08-16",28540026,"Anney RJL","2017-05-22","Mol Autism","www.ncbi.nlm.nih.gov/pubmed/28540026","Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.","Autism spectrum disorder or schizophrenia","schizophrenia cases and controls (see Ripke, 2014), up to 6,197 European ancestry ASD cases, up to 7,377 European ancestry controls, up to 1,190 ASD cases, up to 1,190 controls","NA","6p22.1","GABBR1, GPX5, GPX6, HCG14, HIST1H1B, HIST1H2AI, HIST1H2AJ, HIST1H2AK, HIST1H2AL, HIST1H2AM, HIST1H2BL, HIST1H2BM, HIST1H2BN, HIST1H2BO, HIST1H3H, HIST1H3I, HIST1H3J, HIST1H4J, HIST1H4K, HIST1H4L, LINC01012, LINC01015, LINC01556, LINC01623, LOC100129636, LOC100131289, MAS1L, MOG, NKAPL, OR10C1, OR11A1, OR12D2, OR12D3, OR14J1, OR2B2, OR2B3, OR2B6, OR2H1, OR2H2, OR2J2, OR2J3, OR2W1, OR5V1, PGBD1, SNORD32B, TOB2P1, TRIM27, UBD, ZBED9, ZFP57, ZKSCAN3, ZKSCAN4, ZKSCAN8, ZNF165, ZNF192P1, ZNF311, ZSCAN12, ZSCAN12P1, ZSCAN16, ZSCAN16-AS1, ZSCAN23, ZSCAN26, ZSCAN31, ZSCAN9","LINC00533 - RPSAP2","ENSG00000249032","ENSG00000249814",null,50826,32125,"rs116137698-A","rs116137698",1,35044849,"intergenic_variant",1,null,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,1.22,"[1.17-1.26]","Affymetrix, Illumina [NR]","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,"(Phosphatidylcholine with acyl-alkyl residue sum C34:3/Phosphatidylcholine with acyl-alkyl residue sum C36:5)",0.43919,"[0.36-0.52] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","HDL cholesterol","1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,"(additive)",2.47,"[2.02-2.92] unit decrease","Affymetrix [583469]","N"]
[24,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":4e-26,"d":"4.00E-26"},25.397940008672,null,0.066,"[0.054-0.078] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs140824606",19,45311084,"rs140824606","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","AC092306.1 - BCAM","ENSG00000285128","ENSG00000187244",null,3817,1232,"rs140824606-?","rs140824606",0,140824606,"regulatory_region_variant",1,"NR",{"v":4e-26,"d":"4.00E-26"},25.397940008672,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":4e-26,"d":"4.00E-26"},25.397940008672,null,0.1421661,"[NR] unit decrease","Illumina [575353]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (small molecules and protein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.64,{"v":7e-26,"d":"7.00E-26"},25.1549019599857,"(Alanine)",0.1,"[0.08-0.12] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[23,"rs6471717",8,59353534,"rs13277801","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8q12.1","CYP7A1","UBXN2B",null,null,"ENSG00000215114",null,null,"rs13277801-T","rs13277801",0,13277801,"intron_variant",0,0.653,{"v":8e-26,"d":"8.00E-26"},25.096910013008,"(Trans-ethnic initial)",0.0383,"[0.031-0.045] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":8e-26,"d":"8.00E-26"},25.096910013008,"(Killer cell immunoglobulin-like receptor 2DL5A, KIR2DL5A.7799.3.3)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[8,"rs668948",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":1E-25,"d":"1.00E-25"},25,"(APOB.assay, fasting)",4.355,"[NR] unit decrease","Illumina [335603]","N"]
[24,"rs2954021",8,126490972,"rs2954029","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.5421,{"v":1E-25,"d":"1.00E-25"},25,null,0.0666,"[0.054-0.079] unit increase","NR [8041861] (imputed)","N"]
[43,"rs576249617",19,11227602,"rs688","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs688-C","rs688",0,688,"synonymous_variant",0,0.578,{"v":1E-25,"d":"1.00E-25"},25,"(EA)",0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(EA)",0.109,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.09,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.065,"[0.053-0.077] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-C","rs174546",0,174546,"3_prime_UTR_variant",0,0.668,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(EA)",0.051,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs4803748",19,45242740,"rs2927439","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,13425,8222,"rs2927439-A","rs2927439",0,2927439,"intergenic_variant",1,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.209,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,"(Hispanic)",0.192,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-?","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[23,"rs6471717",8,59370320,"rs4738679","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,6260,32417,"rs4738679-G","rs4738679",0,4738679,"intergenic_variant",1,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"11:61625723_CA_C",11,61639573,"rs174448","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","FADS3","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.01,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[31,"rs5072",11,116722041,"rs10047462","2011-01-15",21149283,"Oexle K","2010-12-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21149283","Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.","Iron status biomarkers","Up to 6,616 individuals","NA","11q23.3","APOA","APOA1-AS, SIK3",null,null,"ENSG00000235910, ENSG00000160584",null,null,"rs10047462-T","rs10047462",0,10047462,"intron_variant",0,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,"(sTfR)",0.041,"[0.03-0.05] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[43,"rs142158911",19,11193949,"rs10412048","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19p13.2","intergenic","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,3847,6089,"rs10412048-G","rs10412048",0,10412048,"intergenic_variant",1,0.1086,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,null,0.18101913,"[0.15-0.22] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[10,"rs11887534",2,44073656,"rs41360247","2010-07-01",20529992,"Teupser D","2010-06-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20529992","Genetic regulation of serum phytosterol levels and risk of coronary artery disease.","Phytosterol levels","1,495 European ancestry individuals","2,917 European ancestry individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs41360247-C","rs41360247",0,41360247,"non_coding_transcript_exon_variant",0,0.064,{"v":6e-25,"d":"6.00E-25"},24.2218487496163,"(campesterol)",14,"[NR] % decrease","Affymetrix [374370]","N"]
[18,"6:160560880_CATG_C",6,160564476,"rs662138","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-G","rs662138",0,662138,"intron_variant",0,0.163,{"v":7e-25,"d":"7.00E-25"},24.1549019599857,"(isobutyrylcarnitine + 3 other traits)",0.155,"[NR] unit decrease","Affymetrix, Illumina [534665]","N"]
[30,"rs174564",11,61570783,"rs174547","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-?","rs174547",0,174547,"intron_variant",0,"NR",{"v":7e-25,"d":"7.00E-25"},24.1549019599857,{"$nulls":3},"Affymetrix [NR]","N"]
[18,"6:160560880_CATG_C",6,160564476,"rs662138","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-C","rs662138",0,662138,"intron_variant",0,0.83,{"v":9e-25,"d":"9.00E-25"},24.0457574905606,"(X-11261)",0.063,"[0.051-0.075] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[38,"rs3816117",16,57005479,"rs1532624","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","16q13","NLRC5, SLC12A3, HERPUD1, CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-A","rs1532624",0,1532624,"intron_variant",0,0.43,{"v":1e-24,"d":"1.00E-24"},24,null,0.23,"[0.19-0.27] unit increase","Illumina [1361436] (imputed)","N"]
[18,"rs10455872",6,161108144,"rs2315065","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","6q26","PLG","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,10589,11176,"rs2315065-A","rs2315065",0,2315065,"intergenic_variant",1,0.06,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,1.3,"[1.24-1.36]","Affymetrix, Illumina [8600000] (imputed)","N"]
[20,"rs1461729",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,{"$nulls":3},"NR [2501749] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.08948,"[0.072-0.107] unit decrease novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-01-23",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Homeostasis model assessment of insulin resistance","37,037 European ancestry individuals","62,264 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.035,"[0.027-0.043] unit increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-09-22",28739976,"Wain LV","2017-07-24","Hypertension","www.ncbi.nlm.nih.gov/pubmed/28739976","Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.","Diastolic blood pressure","150,134 European ancestry individuals","87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.523,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,"(EA, initial)",0.457,"[0.37-0.55] unit decrease","Affymetrix, Illumina, Perlegen [7994604] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2016-12-08",26830138,"Herold C","2016-02-02","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/26830138","Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.","Alzheimer disease and age of onset","2,478 European ancestry cases, 979 ancestry controls both from the same 1,070 families","NA","19q13.32","Intergenic","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-A","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":3E-24,"d":"3.00E-24"},23.5228787452803,"(within families)",10.157,"unit increase","Affymetrix [up to 15107142] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(GGT2)",0.51045436,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[26,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(EA)",0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.34,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,null,3.82,"[3.08-4.56] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs74410908",2,21250914,"rs679899","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs679899-G","rs679899",0,679899,"missense_variant",0,0.503,{"v":6e-24,"d":"6.00E-24"},23.2218487496163,"(APOB)",0.246,"[0.2-0.29] unit decrease","Illumina [> 1000000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-10-17",28937693,"Clarke TK","2017-07-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28937693","Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).","Alcohol consumption in current drinkers","108,309 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-G","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":7e-24,"d":"7.00E-24"},23.1549019599857,null,0.03,"[0.024-0.036] unit decrease","Affymetrix [12489781] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.878,{"v":8e-24,"d":"8.00E-24"},23.096910013008,"(APOA5)",0.371,"[0.3-0.44] unit increase","Illumina [> 1000000] (imputed)","N"]
[20,"rs1461729",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,0.071,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.199,{"v":1e-23,"d":"1.00E-23"},23,"(Hispanic)",0.19,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs58065809",11,117079433,"rs199605734","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","PCSK7","PCSK7, AP000892.3",null,null,"ENSG00000160613, ENSG00000280143",null,null,"rs199605734-G","rs199605734",1,1784617,"non_coding_transcript_exon_variant",0,0.208,{"v":1e-23,"d":"1.00E-23"},23,"(Proprotein convertase subtilisin/kexin type 7, PCSK7.4459.68.2)",0.31,"[0.25-0.37] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs157581",19,45396219,"rs157582","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157582-?","rs157582",0,157582,"intron_variant",0,"NR",{"v":1e-23,"d":"1.00E-23"},23,"(males)",2.8279662,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs111606839",19,45490192,"rs11672748","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","CLPTM1","CLPTM1",null,null,"ENSG00000104853",null,null,"rs11672748-G","rs11672748",0,11672748,"non_coding_transcript_exon_variant",0,0.3171,{"v":1e-23,"d":"1.00E-23"},23,null,10.028075,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[20,"rs1461729",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(KIN)",0.4950121,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,null,0.389,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":4e-23,"d":"4.00E-23"},22.397940008672,null,1.7063565,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs1065853",19,45415640,"rs445925","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.08,{"v":5e-23,"d":"5.00E-23"},22.3010299956639,"(X-11820/cholesterol)",0.089,"[0.071-0.107] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[21,"rs615632",8,10009952,"rs11993089","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Pulse pressure x alcohol consumption interaction (2df test)","91,099 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","238,053 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,447 Hispanic ancestry drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic ancestry non-drinkers","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs11993089-T","rs11993089",0,11993089,"intron_variant",0,0.42,{"v":6e-23,"d":"6.00E-23"},22.2218487496163,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.16,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[27,"rs115478735",9,136155000,"rs635634","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Myeloid white cell count","169,219 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.1825,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.04578683,"[0.037-0.055] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[52,"rs372038686",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,"NR",{"v":9e-23,"d":"9.00E-23"},22.0457574905606,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"6:160560880_CATG_C",6,160564476,"rs662138","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-C","rs662138",0,662138,"intron_variant",0,0.83,{"v":1E-22,"d":"1.00E-22"},22,"(X-03056--N-[3-(2-oxopyrrolidin-1-yl)propyl]acetamide)",0.034,"[0.026-0.042] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1E-22,"d":"1.00E-22"},22,"(LIFR)",0.337,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":1E-22,"d":"1.00E-22"},22,"(EA)",0.048,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1E-22,"d":"1.00E-22"},22,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs668948",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(LDL.total, whole)",0.04,"[NR] unit decrease","Illumina [335603]","N"]
[30,"rs174564",11,61569830,"rs174546","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-C","rs174546",0,174546,"3_prime_UTR_variant",0,0.34,{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,1.78,"[1.39-2.17] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[33,"rs35350651",12,112059557,"rs11065979","2018-10-18",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption interaction (2df test)","63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers,  2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers","12q24.12","BRAP","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.45,{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[14,"rs6882345",5,156398169,"rs1501908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,0.366,{"v":3e-22,"d":"3.00E-22"},21.5228787452803,"(EA)",0.042,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs6471717",8,59370320,"rs4738679","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,6260,32417,"rs4738679-G","rs4738679",0,4738679,"intergenic_variant",1,"NR",{"v":3e-22,"d":"3.00E-22"},21.5228787452803,null,0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid AB1-42 levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,null,{"v":3e-22,"d":"3.00E-22"},21.5228787452803,{"$nulls":3},"Illumina [563980]","N"]
[22,"rs7816447",8,19847690,"rs10503669","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,22920,88935,"rs10503669-C","rs10503669",0,10503669,"intergenic_variant",1,0.9,{"v":4e-22,"d":"4.00E-22"},21.397940008672,null,11.57,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[3,"rs34232196",1,55487346,"rs12117661","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","BSND - PCSK9","ENSG00000162399","ENSG00000169174",null,9889,17875,"rs12117661-C","rs12117661",0,12117661,"regulatory_region_variant",1,0.751,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,"(EA)",0.052,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs11250098",8,11061792,"rs6981523","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","NR","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,612,43343,"rs6981523-T","rs6981523",0,6981523,"intergenic_variant",1,0.50684,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.054139,"[0.043-0.065] unit increase","Illumina [18485882] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-G","rs562338",0,562338,"intergenic_variant",1,0.82,{"v":6e-22,"d":"6.00E-22"},21.2218487496163,null,4.89,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau:AB1-42 ratio","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":6e-22,"d":"6.00E-22"},21.2218487496163,{"$nulls":3},"Illumina [563980]","N"]
[27,"rs115478735",9,136155000,"rs635634","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.22,{"v":8e-22,"d":"8.00E-22"},21.096910013008,null,2.05,"[1.64-2.46] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.884,{"v":8e-22,"d":"8.00E-22"},21.096910013008,null,1.14,"[1.11-1.17]","Affymetrix [9149595] (imputed)","N"]
[47,"rs8111874",19,49206674,"rs601338","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs601338-?","rs601338",0,601338,"stop_gained",0,null,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,null,1.098901,"[1.08-1.11]","Affymetrix, Illumina [43000000] (imputed)","N"]
[8,"rs74410908",2,21250914,"rs679899","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs679899-G","rs679899",0,679899,"missense_variant",0,0.503125,{"v":1e-21,"d":"1.00E-21"},21,"(SLC5A8)",0.23186418,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.35,{"v":1e-21,"d":"1.00E-21"},21,null,1.71,"[1.34-2.08] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs174564",11,61571348,"rs174548","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174548-?","rs174548",0,174548,"5_prime_UTR_variant",0,"NR",{"v":1e-21,"d":"1.00E-21"},21,"(arachidonate204n6)",0.0414,"[NR] unit decrease","Affymetrix [655658]","N"]
[9,"rs74175068",2,27755825,"rs4665987","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Creatinine levels","142,097 Japanese ancestry individuals","NA","2p23.3","GCKR, C2orf16","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,9274,4428,"rs4665987-?","rs4665987",0,4665987,"intergenic_variant",1,"NR",{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.03616,"[0.029-0.044] unit decrease novel","Illumina [6108953] (imputed)","N"]
[23,"rs6471717",8,59353534,"rs13277801","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B",null,null,"ENSG00000215114",null,null,"rs13277801-C","rs13277801",0,13277801,"intron_variant",0,0.34,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(EA)",0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2014-01-10",23844046,"Dorajoo R","2013-07-02","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23844046","Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?","C-reactive protein","2,179 Chinese ancestry individuals, 2,275 Malay ancestry individuals, 2,238 Asian Indian ancestry individuals","NA","19q13.32","APOE","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,0.122,{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.116,"[NR] unit increase","Illumina [up to 1745429] (imputed)","N"]
[46,"rs2238681",19,45403412,"rs1160985","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","LDL cholesterol","7,861 African American individuals, 3,425 Hispanic individuals","7,138 African American individuals","19q13.32","APOE","TOMM40",{"$nulls":5},"rs1160985-C","rs1160985",0,1160985,"intron_variant",0,0.365,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(AA)",6.772,"[NR] unit increase","Affymetrix [NR]","N"]
[21,"rs615632",8,9796321,"rs615632","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","intergenic","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,33445,111674,"rs615632-T","rs615632",0,615632,"intergenic_variant",1,0.52895,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,9.469,"z score increase","Illumina [18485882] (imputed)","N"]
[30,"rs2072114",11,61603237,"rs2727270","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)","8,631 European ancestry individuals","NA","11q12.2","FTH1, INCENP, FADS1, FADS2, SCGB1D1, SCGB2A1, C11orf9, DAGLA, FEN1, RAB3IL, C11orf10, FADS3, SYT7, BEST1, SCGB1D2","FADS2",null,null,"ENSG00000134824",null,null,"rs2727270-T","rs2727270",0,2727270,"intron_variant",0,0.44,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,"(Conditioned on rs174547)",0.69,"[0.55-0.83] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Cerebral amyloid angiopathy","1,673 cases, 1,134 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3429,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.6708,"[0.53-0.81] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[46,"rs157581",19,45396219,"rs157582","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157582-?","rs157582",0,157582,"intron_variant",0,null,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.1078951,"[NR] unit decrease","Illumina [575353]","N"]
[23,"rs6471717",8,59311697,"rs1030431","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","AC092819.1 - UBXN2B","ENSG00000253281","ENSG00000215114",null,127019,12126,"rs1030431-A","rs1030431",0,1030431,"intergenic_variant",1,"NR",{"v":4e-21,"d":"4.00E-21"},20.397940008672,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Systolic blood pressure","approximately 422,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":4e-21,"d":"4.00E-21"},20.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2019-01-11",30054458,"Xue A","2018-07-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30054458","Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.","Type 2 diabetes","61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.387154700626533,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,0.0692,"[0.055-0.084] unit decrease","NR [5035015] (imputed)","N"]
[30,"rs174564",11,61592362,"rs174566","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174566-G","rs174566",0,174566,"intron_variant",0,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,"(Phosphatidylcholine with diacyl residue sum C36:5/Phosphatidylcholine with acyl-alkyl residue sum C38:0)",0.405654,"[0.32-0.49] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2016-09-12",26421299,"Li J","2015-09-03","Biomed Res Int","www.ncbi.nlm.nih.gov/pubmed/26421299","Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort.","Cingulate cortical amyloid beta load","215 European ancestry early mild cognitive impairment cases, 152 European ancestry late mild cognitive impairment cases, 45 European ancestry Alzheimer disease cases, 190  European ancestry controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,{"$nulls":3},"Illumina [582718]","N"]
[26,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":6e-21,"d":"6.00E-21"},20.2218487496163,"(EA)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":6e-21,"d":"6.00E-21"},20.2218487496163,"(EA)",0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61569306,"rs174545","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174545-G","rs174545",0,174545,"3_prime_UTR_variant",0,"NR",{"v":7e-21,"d":"7.00E-21"},20.1549019599857,"(Phosphatidylcholine with acyl-alkyl residue sum C36:3/Phosphatidylcholine with acyl-alkyl residue sum C40:1)",0.407966,"[0.32-0.49] unit increase","Illumina [up to 9281895] (imputed)","N"]
[44,"rs58542926",19,19329924,"rs2228603","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2228603-T","rs2228603",0,2228603,"missense_variant",0,"NR",{"v":7e-21,"d":"7.00E-21"},20.1549019599857,{"$nulls":3},"NR [2501749] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-A","rs115849089",0,115849089,"intergenic_variant",1,0.1163,{"v":8e-21,"d":"8.00E-21"},20.096910013008,null,0.0518692,"[0.041-0.063] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs247617",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.685,{"v":8e-21,"d":"8.00E-21"},20.096910013008,"(EA)",0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[52,"rs372038686",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,0.597,{"v":8e-21,"d":"8.00E-21"},20.096910013008,"(EA)",0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112200150,"rs2013002","2018-10-18",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption interaction (2df test)","63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers,  2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers","12q24.12","ALDH2","AC002996.1",null,null,"ENSG00000257767",null,null,"rs2013002-T","rs2013002",0,2013002,"intron_variant",0,0.4,{"v":9e-21,"d":"9.00E-21"},20.0457574905606,"(AA, EA, Hispanic)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[13,"rs4704210",5,74648603,"rs12654264","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","5q13.3","HMGCR","HMGCR",null,null,"ENSG00000113161",null,null,"rs12654264-T","rs12654264",0,12654264,"intron_variant",0,0.39,{"v":1e-20,"d":"1.00E-20"},20,null,0.1,"[0.08-0.12] unit increase","Affymetrix [389878]","N"]
[16,"rs1233489",6,29461730,"rs1233491","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","MAS1L, LOC729653","RPS17P1 - AL662860.1","ENSG00000213900","ENSG00000229274",null,4277,3556,"rs1233491-C","rs1233491",0,1233491,"intergenic_variant",1,0.23,{"v":1e-20,"d":"1.00E-20"},20,{"$nulls":3},"Illumina [118177]","N"]
[24,"rs2954021",8,126477978,"rs2001945","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-C","rs2001945",0,2001945,"intergenic_variant",1,0.42,{"v":1e-20,"d":"1.00E-20"},20,null,0.0405,"[0.032-0.049] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[30,"rs174564",11,61571382,"rs174549","2015-06-08",25194280,"Wei Q","2014-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25194280","Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.","Laryngeal squamous cell carcinoma","993 Chinese ancestry cases, 1,995 Chinese ancestry controls","2,398 Chinese ancestry cases, 2,804 Chinese ancestry controls","11q12.2","FADS1, FADS2, FADS3, FEN1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174549-?","rs174549",0,174549,"5_prime_UTR_variant",0,0.59,{"v":1e-20,"d":"1.00E-20"},20,null,1.37,"[1.28-1.47]","Affymetrix [662108]","N"]
[37,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":1e-20,"d":"1.00E-20"},20,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1e-20,"d":"1.00E-20"},20,"(TMCC3)",0.4673718,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2008-09-15",18262040,"Sandhu MS","2008-02-09","Lancet","www.ncbi.nlm.nih.gov/pubmed/18262040","LDL-cholesterol concentrations: a genome-wide association study.","LDL cholesterol","11,685 European ancestry individuals","Up to 4,979 European ancestry individuals","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":1e-20,"d":"1.00E-20"},20,null,0.06,"[0.04-0.08] mmol/L increase","Affymetrix, Illumina [up to 461986]","N"]
[8,"rs6544366",2,21221035,"rs4665710","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-C","rs4665710",0,4665710,"intergenic_variant",1,0.794,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(Sodium-coupled monocarboxylate transporter 1, SLC5A8.13691.10.3)",0.28,"[0.22-0.34] unit decrease","Affymetrix [10572788] (imputed)","N"]
[24,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111865049,"rs7310615","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","SH2B3","SH2B3",null,null,"ENSG00000111252",null,null,"rs7310615-C","rs7310615",0,7310615,"intron_variant",0,0.45,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(AA, EA, Hispanic)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(EA)",0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.15,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(Apolipoprotein B, APOB.2797.56.2)",0.43,"[0.33-0.53] unit decrease","Affymetrix [10572788] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","11q12.2","C11orf10, C11orf9, FADS1, FADS2, FEN1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-?","rs174547",0,174547,"intron_variant",0,"NR",{"v":3e-20,"d":"3.00E-20"},19.5228787452803,"(1arachidonoylglycerophosphocholine)",0.05788,"[NR] unit decrease","Affymetrix [655658]","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5176,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,0.03291189,"[0.026-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.892,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,"(AA)",0.381,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.03395389,"[0.027-0.041] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[23,"rs6471717",8,59393273,"rs4738684","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,29213,9464,"rs4738684-A","rs4738684",0,4738684,"regulatory_region_variant",1,0.341,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(EA)",0.045,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(SHANK3)",0.314,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5505,{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.0258,"[0.02-0.031] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[52,"rs372038686",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,0.592,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-20,"d":"5.00E-20"},19.3010299956639,"(Phosphatidylcholine with acyl-alkyl residue sum C36:5/Sphingomyelin with acyl residue sum C24:1)",0.394712,"[0.31-0.48] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[30,"rs174564",11,61581764,"rs174560","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174560-C","rs174560",0,174560,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-20,"d":"5.00E-20"},19.3010299956639,"(Phosphatidylcholine with diacyl residue sum C42:4/Phosphatidylcholine with acyl-alkyl residue sum C38:3)",0.397827,"[0.31-0.48] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-A","rs780094",0,780094,"intron_variant",0,0.36,{"v":6e-20,"d":"6.00E-20"},19.2218487496163,"(TG)",0.13,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","11p11.2","NR","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-C","rs3817334",0,3817334,"intron_variant",0,"NR",{"v":6e-20,"d":"6.00E-20"},19.2218487496163,null,0.023,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[14,"rs6882345",5,156479323,"rs1553318","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-G","rs1553318",0,1553318,"intron_variant",0,0.369,{"v":7e-20,"d":"7.00E-20"},19.1549019599857,"(EA)",0.044,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,28803291,"rs9257248","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","LOC442181, LOC401242","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,51510,2355,"rs9257248-A","rs9257248",0,9257248,"intergenic_variant",1,0.217,{"v":7e-20,"d":"7.00E-20"},19.1549019599857,{"$nulls":3},"Illumina [118177]","N"]
[31,"rs964184",11,116648917,"rs964184","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":8e-20,"d":"8.00E-20"},19.096910013008,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.39,{"v":9e-20,"d":"9.00E-20"},19.0457574905606,null,1.54,"[1.15-1.93] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[26,"rs4149307",9,107591272,"rs2853579","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2853579-G","rs2853579",0,2853579,"synonymous_variant",0,"NR",{"v":1e-19,"d":"1.00E-19"},19,null,0.053,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Hemoglobin levels","up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.","16,389 European and African American individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-?","rs495828",0,495828,"regulatory_region_variant",1,"NR",{"v":1e-19,"d":"1.00E-19"},19,{"$nulls":3},"Affymetrix, Illumina [2500000] (imputed)","N"]
[31,"rs35120633",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.936,{"v":1e-19,"d":"1.00E-19"},19,"(EA)",0.086,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1e-19,"d":"1.00E-19"},19,"(CTF1)",0.4569444,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[9,"rs1260326",2,27748624,"rs1260333","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2073,11629,"rs1260333-C","rs1260333",0,1260333,"intergenic_variant",1,0.55,{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.05,"[0.04-0.06] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","2p21",null,"ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-?","rs4299376",0,4299376,"intron_variant",0,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[33,"rs35350651",12,111932800,"rs7137828","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-T","rs7137828",0,7137828,"intron_variant",0,0.53,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(EA, Hispanic)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[38,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.883,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(Beta-defensin 119, DEFB119.8370.102.3)",0.41,"[0.31-0.51] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs111606839",19,45440529,"rs73045691","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,5886,4966,"rs73045691-?","rs73045691",0,73045691,"intergenic_variant",1,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[23,"rs6471717",8,59370320,"rs4738679","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,6260,32417,"rs4738679-G","rs4738679",0,4738679,"intergenic_variant",1,0.337,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(EA)",0.045,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61552680,"rs174537","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","MYRF, FADS1, FADS2, FADS3","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174537-T","rs174537",0,174537,"non_coding_transcript_exon_variant",0,0.3202,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(Phosphatidylcholine diacyl C36:2)",0.0356,"[0.028-0.043] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[33,"rs35350651",12,111833788,"rs10774624","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Systolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","12q24.12","SH2B3","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-G","rs10774624",0,10774624,"intron_variant",0,0.6576,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.481,"[0.38-0.59] mmHg decrease","Affymetrix [NR] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs2179372",20,39672618,"rs6029526","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6029526-A","rs6029526",0,6029526,"intron_variant",0,0.47,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,1.41,"[1.08-1.74] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[23,"rs6471717",8,59353534,"rs13277801","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q12.1","CYP7A1","UBXN2B",null,null,"ENSG00000215114",null,null,"rs13277801-T","rs13277801",0,13277801,"intron_variant",0,0.653,{"v":4e-19,"d":"4.00E-19"},18.397940008672,"(Trans-ethnic initial)",0.0338,"[0.026-0.041] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[33,"rs35350651",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Immature fraction of reticulocytes","170,548 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5028,{"v":4e-19,"d":"4.00E-19"},18.397940008672,null,0.03163296,"[0.025-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,null,0.03251663,"[0.025-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,"(EA)",0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44073881,"rs6544713","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","2p21","ABCG5, ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs6544713-T","rs6544713",0,6544713,"non_coding_transcript_exon_variant",0,0.3018,{"v":6e-19,"d":"6.00E-19"},18.2218487496163,null,0.0549,"[0.043-0.067] unit increase","NR [8041861] (imputed)","N"]
[46,"rs2238681",19,45410444,"rs769450","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769450-G","rs769450",0,769450,"non_coding_transcript_exon_variant",0,0.61311,{"v":6e-19,"d":"6.00E-19"},18.2218487496163,null,1.59501,"[1.44-1.75]","Affymetrix, Illumina [2928658] (imputed)","N"]
[14,"rs6882345",5,156479323,"rs1553318","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-G","rs1553318",0,1553318,"intron_variant",0,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs58065809",11,117003749,"rs4938344","2017-05-11",28031287,"Sasayama D","2016-11-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28031287","Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.","Cerebrospinal fluid biomarker levels","133 Japanese ancestry individuals.","NA","11q23.3","NR","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,13852,2495,"rs4938344-?","rs4938344",0,4938344,"intergenic_variant",1,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,"(Proprotein convertase subtilisin/kexin type 7)",null,null,"Illumina [514227]","N"]
[42,"rs12608026",18,47118923,"rs3786247","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs3786247-T","rs3786247",0,3786247,"3_prime_UTR_variant",0,0.6,{"v":7e-19,"d":"7.00E-19"},18.1549019599857,"(Asian initial, BMI unadjusted)",0.094,"[0.074-0.114] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[22,"rs11986942",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.696,{"v":8e-19,"d":"8.00E-19"},18.096910013008,"(Hispanic)",0.13,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs11065358",12,121416650,"rs1169288","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","12q24.31","HNF1A, HNF1A-AS1","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.67,{"v":8e-19,"d":"8.00E-19"},18.096910013008,null,0.054,"[0.042-0.066] unit decrease","Affymetrix [7947838] (imputed)","N"]
[21,"rs11250098",8,11062882,"rs7010590","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Well-being spectrum (multivariate analysis)","2,083,151 European ancestry individuals","287,239 European ancestry individuals","8p23.1","NR","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,1702,42253,"rs7010590-C","rs7010590",0,7010590,"intergenic_variant",1,0.508096355670064,{"v":1e-18,"d":"1.00E-18"},18,null,8.087126E-3,"[0.0063-0.0099] unit increase","NR [NR]","N"]
[30,"rs61897793",11,61556039,"rs61896141","2019-01-30",30531825,"Morgan MD","2018-12-10","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30531825","Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.","Blond vs. brown/black hair color","39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals","NA","11q12.2","MYRF","TMEM258",null,null,"ENSG00000134825",null,null,"rs61896141-C","rs61896141",0,61896141,"intron_variant",0,0.1893,{"v":1e-18,"d":"1.00E-18"},18,null,1.089,"NR","Affymetrix [9154080] (imputed)","N"]
[30,"rs174564",11,61592362,"rs174566","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174566-G","rs174566",0,174566,"intron_variant",0,"NR",{"v":1e-18,"d":"1.00E-18"},18,"(Phosphatidylcholine with acyl-alkyl residue sum C38:2/Phosphatidylcholine with acyl-alkyl residue sum C40:4)",0.378422,"[0.3-0.46] unit increase","Illumina [up to 9281895] (imputed)","N"]
[34,"rs11065358",12,121416650,"rs1169288","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","12q24.31","HNF1A, HNF1A-AS1","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.6725,{"v":1e-18,"d":"1.00E-18"},18,null,0.049,"[0.038-0.06] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid AB1-42 levels","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":1e-18,"d":"1.00E-18"},18,null,301.1457,"[NR] unit increase","Illumina [575353]","N"]
[10,"rs4299376",2,44073881,"rs6544713","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","2p21","ABCG5, ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs6544713-T","rs6544713",0,6544713,"non_coding_transcript_exon_variant",0,0.3038,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.0492,"[0.038-0.06] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[22,"rs73600084",8,19830921,"rs10096633","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-G","rs10096633",0,10096633,"regulatory_region_variant",1,0.88,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.17,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[23,"rs6471717",8,59311697,"rs1030431","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","AC092819.1 - UBXN2B","ENSG00000253281","ENSG00000215114",null,127019,12126,"rs1030431-A","rs1030431",0,1030431,"intergenic_variant",1,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs1800978",9,107653426,"rs12686004","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-T","rs12686004",0,12686004,"intron_variant",0,0.21,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.0217,"[0.017-0.027] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[30,"rs174564",11,61565908,"rs174541","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FEN1, FADS1","FADS2",null,null,"ENSG00000134824",null,null,"rs174541-C","rs174541",0,174541,"intron_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(Phosphatidylcholine with acyl-alkyl residue sum C36:3/Phosphatidylcholine with acyl-alkyl residue sum C40:5)",0.380947,"[0.3-0.46] unit increase","Illumina [up to 9281895] (imputed)","N"]
[42,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.175,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs111371860",19,45345787,"rs111371860","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,21109,3645,"rs111371860-?","rs111371860",0,111371860,"intergenic_variant",1,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[47,"rs8111874",19,49206417,"rs492602","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-A","rs492602",0,492602,"synonymous_variant",0,0.518,{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(EA)",0.04,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Metabolite levels","8,330 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(Ala, Gln)",0.15,"[0.11-0.19] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[30,"rs174564",11,61549458,"rs174534","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174534-A","rs174534",0,174534,"non_coding_transcript_exon_variant",0,0.647163,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.0168583,"[0.013-0.021] unit decrease","NR [13737936] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-G","rs1535",0,1535,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(Phosphatidylcholine with diacyl residue sum C36:2/Phosphatidylcholine with acyl-alkyl residue sum C38:6)",0.386446,"[0.3-0.47] unit increase","Illumina [up to 9281895] (imputed)","N"]
[37,"15:58682029_TGAA_T",15,58687790,"rs495348","2018-07-13",29632305,"Lee HS","2018-04-09","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29632305","New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.","Metabolic syndrome (multivariate analysis)","1,946 Korean ancestry cases, 6,427 Korean ancestry controls","430 Korean ancestry cases, 3,264 Korean ancestry controls","15q21.3","LOC101928635","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs495348-?","rs495348",0,495348,"intron_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,{"$nulls":3},"Affymetrix [344366]","N"]
[30,"rs174564",11,61543961,"rs174529","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","11q12.2",null,"TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-?","rs174529",0,174529,"intron_variant",0,"NR",{"v":4e-18,"d":"4.00E-18"},17.397940008672,null,0.0191264,"[0.015-0.023] unit decrease","Affymetrix [20259828] (imputed)","N"]
[42,"rs77960347",18,47109955,"rs77960347","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","18q21.1",null,"LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-?","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":4e-18,"d":"4.00E-18"},17.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[42,"rs4939883",18,47160953,"rs7241918","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.19,{"v":4e-18,"d":"4.00E-18"},17.397940008672,null,0.058,"[NR] unit decrease","NR [NR] (imputed)","N"]
[31,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.249,{"v":5e-18,"d":"5.00E-18"},17.3010299956639,"(East Asian)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs36013629",19,50038017,"rs10419198","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum total protein level","113,509 Japanese ancestry individuals","NA","19q13.33","NR","RCN3",null,null,"ENSG00000142552",null,null,"rs10419198-?","rs10419198",0,10419198,"intron_variant",0,"NR",{"v":5e-18,"d":"5.00E-18"},17.3010299956639,null,0.04644,"[0.036-0.057] unit decrease novel","Illumina [6108953] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.49,{"v":6e-18,"d":"6.00E-18"},17.2218487496163,"(kynurenine)",0.015,"[0.011-0.019] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":6e-18,"d":"6.00E-18"},17.2218487496163,null,0.316,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[30,"rs174564",11,61581764,"rs174560","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174560-C","rs174560",0,174560,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-18,"d":"7.00E-18"},17.1549019599857,"(Phosphatidylcholine with diacyl residue sum C36:3/Phosphatidylcholine with diacyl residue sum C42:5)",0.38643,"[0.3-0.47] unit increase","Illumina [up to 9281895] (imputed)","N"]
[18,"rs186696265",6,161111700,"rs186696265","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.985233,{"v":8e-18,"d":"8.00E-18"},17.096910013008,null,0.0802938,"[0.062-0.099] unit decrease","Affymetrix [11535925] (imputed)","N"]
[6,"rs822928",1,234858597,"rs514230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-A","rs514230",0,514230,"intergenic_variant",1,"NR",{"v":9e-18,"d":"9.00E-18"},17.0457574905606,null,0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs615632",8,9803712,"rs13271489","2018-09-05",29455858,"Sung YJ","2018-02-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29455858","A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.","Systolic blood pressure x smoking status (ever vs never) interaction (2df test)","43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers","139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers","8p23.1","MIR124-1, MSRA","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,40836,104283,"rs13271489-?","rs13271489",0,13271489,"intergenic_variant",1,"NR",{"v":9e-18,"d":"9.00E-18"},17.0457574905606,{"$nulls":3},"Affymetrix, Illumina [18800000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":9e-18,"d":"9.00E-18"},17.0457574905606,null,0.05598592,"[0.043-0.069] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72877166,"rs2074755","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2074755-?","rs2074755",0,2074755,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-17,"d":"1.00E-17"},17,{"$nulls":3},"Affymetrix [NR]","N"]
[22,"rs11986942",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.705,{"v":1e-17,"d":"1.00E-17"},17,"(Hispanic)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61603510,"rs174576","2016-06-02",26068415,"Draisma HHM","2015-06-12","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26068415","Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.","Glycerophospholipid levels","up to 7,478 European ancestry individuals","1,182 European ancestry individuals","11q12.2","FADS2, FADS1, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs174576-A","rs174576",0,174576,"intron_variant",0,0.3206,{"v":1e-17,"d":"1.00E-17"},17,"(Phosphatidylcholine diacyl C34:2)",0.0305,"[0.023-0.038] unit increase","Affymetrix, Illumina [at least 296619] (imputed)","N"]
[37,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.588,{"v":1e-17,"d":"1.00E-17"},17,"(East Asian)",0.116,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs822928",1,234853268,"rs557933","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6",null,null,"ENSG00000282097",null,null,"rs557933-A","rs557933",0,557933,"intron_variant",0,0.477,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(EA)",0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs253412",5,75015242,"rs2112347","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","5q13.3","POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.621,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.025,"[0.02-0.031] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[30,"rs174564",11,61580635,"rs174556","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte percentage of myeloid white cells","169,545 European ancestry individuals","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174556-T","rs174556",0,174556,"intron_variant",0,0.3082,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.03290644,"[0.025-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs174471",11,61663691,"rs174468","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)","8,866 European ancestry individuals","NA","11q12.2","RAB3IL1","FADS3 - RAB3IL1","ENSG00000221968","ENSG00000167994",null,4168,1082,"rs174468-A","rs174468",0,174468,"regulatory_region_variant",1,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.05,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[33,"rs35350651",12,112486818,"rs17696736","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","12q24.13","NAA25","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-G","rs17696736",0,17696736,"intron_variant",0,0.383155352628626,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.41001332,"[0.32-0.5] unit increase","Illumina [247039]","N"]
[47,"rs8111874",19,49213504,"rs2452170","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2 - MAMSTR","ENSG00000176920","ENSG00000176909",null,4297,2495,"rs2452170-G","rs2452170",0,2452170,"intergenic_variant",1,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19840408,"rs75551077","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,15638,96217,"rs75551077-G","rs75551077",0,75551077,"intergenic_variant",1,0.89,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(East Asian)",0.194,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61581764,"rs174560","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174560-C","rs174560",0,174560,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(Phosphatidylcholine with acyl-alkyl residue sum C32:2/Phosphatidylcholine with acyl-alkyl residue sum C36:3)",0.369914,"[0.29-0.45] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[30,"rs174564",11,61600342,"rs174574","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","11q12.2",null,"FADS2",null,null,"ENSG00000134824",null,null,"rs174574-?","rs174574",0,174574,"intron_variant",0,"NR",{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,0.018426,"[0.014-0.023] unit increase","Affymetrix [20259828] (imputed)","N"]
[51,"rs2179372",20,39811275,"rs4297946","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","20q12","TOP1","PLCG1, ZHX3",null,null,"ENSG00000124181, ENSG00000174306",null,null,"rs4297946-C","rs4297946",0,4297946,"3_prime_UTR_variant",0,0.47,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,1.52,"[1.15-1.89] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[24,"rs2954021",8,126486409,"rs17321515","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-G","rs17321515",0,17321515,"intron_variant",0,0.49,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.08,"[0.06-0.10] unit decrease","Affymetrix [389878]","N"]
[38,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,"NR",{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau:AB1-42 ratio","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,null,{"v":4e-17,"d":"4.00E-17"},16.397940008672,{"$nulls":3},"Illumina [563980]","N"]
[30,"rs174564",11,61549025,"rs174533","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174533-A","rs174533",0,174533,"intron_variant",0,"NR",{"v":5e-17,"d":"5.00E-17"},16.3010299956639,"(Phosphatidylcholine with acyl-alkyl residue sum C34:2/Phosphatidylcholine with acyl-alkyl residue sum C38:6)",0.365851,"[0.28-0.45] unit increase","Illumina [up to 9281895] (imputed)","N"]
[47,"rs8111874",19,49206417,"rs492602","2008-09-12",18776911,"Hazra A","2008-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18776911","Common variants of FUT2 are associated with plasma vitamin B12 levels.","Vitamin B12 levels","1,658 European ancestry female individuals","1,059 European ancestry female individuals","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-A","rs492602",0,492602,"synonymous_variant",0,0.51,{"v":5e-17,"d":"5.00E-17"},16.3010299956639,null,0.09,"[0.070-0.110] unit decrease","Illumina [528134]","N"]
[18,"rs10455872",6,161005610,"rs55730499","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (father's attained age)","415,311 British ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-C","rs55730499",0,55730499,"intron_variant",0,"NR",{"v":6e-17,"d":"6.00E-17"},16.2218487496163,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[31,"rs688456",11,116728630,"rs12225230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs12225230-G","rs12225230",0,12225230,"missense_variant",0,"NR",{"v":6e-17,"d":"6.00E-17"},16.2218487496163,null,0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47457539,"rs11604680","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","11p11.2","RAPSN","PSMC3 - RAPSN","ENSG00000165916","ENSG00000165917",null,9515,1769,"rs11604680-A","rs11604680",0,11604680,"regulatory_region_variant",1,0.6793,{"v":7e-17,"d":"7.00E-17"},16.1549019599857,null,0.019941581,"[0.015-0.025] unit increase","Affymetrix [11514936] (imputed)","N"]
[6,"rs822928",1,234853059,"rs556107","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6",null,null,"ENSG00000282097",null,null,"rs556107-C","rs556107",0,556107,"intron_variant",0,0.472,{"v":8e-17,"d":"8.00E-17"},16.096910013008,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.88,{"v":9e-17,"d":"9.00E-17"},16.0457574905606,"(Asian initial, BMI unadjusted)",0.11,"[0.085-0.135] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[46,"19:45531618_GT_G",19,45541782,"rs34827707","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19q13.32","NR","RELB - CLASRP","ENSG00000104856","ENSG00000104859",null,326,516,"rs34827707-A","rs34827707",0,34827707,"regulatory_region_variant",1,0.0340516,{"v":9e-17,"d":"9.00E-17"},16.0457574905606,null,0.272045,"[0.21-0.34] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[12,"rs13108218",4,3443931,"rs13108218","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4p16.3","HGFAC","HGFAC",null,null,"ENSG00000109758",null,null,"rs13108218-A","rs13108218",0,13108218,"intron_variant",0,0.4233,{"v":1e-16,"d":"1.00E-16"},16,null,0.0234,"[0.018-0.029] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs11986942",8,19824492,"rs13702","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs13702-A","rs13702",0,13702,"3_prime_UTR_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.29,"[0.23-0.35] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47669175,"rs59360790","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Body fat percentage","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","11p11.2","NR","MTCH2 - AGBL2","ENSG00000109919","ENSG00000165923",null,5000,11968,"rs59360790-?","rs59360790",0,59360790,"intergenic_variant",1,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.17754,"[0.14-0.22] unit increase","Affymetrix [7794483] (imputed)","N"]
[30,"rs174564",11,61552680,"rs174537","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite concentrations in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174537-T","rs174537",0,174537,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,"(Phosphatidylcholine with diacyl residue sum C38:5)",0.357607,"[0.27-0.44] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[31,"rs6589567",11,116670676,"rs6589567","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","ZNF259","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,7540,13244,"rs6589567-A","rs6589567",0,6589567,"intergenic_variant",1,0.23,{"v":1e-16,"d":"1.00E-16"},16,"(Indian)",13.09,"[9.99-16.19] unit increase","Illumina [551825]","N"]
[33,"rs35350651",12,112059557,"rs11065979","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test)","56,705 European ancestry heavy and light drinkers, 9,725 African American or Afro-Caribbean heavy and light drinkers, 1,789 Asian ancestry heavy and light drinkers, 4,812 Hispanic or Latin American heavy and light drinkers","42,077 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic ancestry heavy drinkers, 74,701 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers","12q24.12","BRAP","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.45,{"v":1e-16,"d":"1.00E-16"},16,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[47,"rs8111874",19,49206172,"rs516246","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-C","rs516246",0,516246,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,null,0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206417,"rs492602","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.33","FLJ36070","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-G","rs492602",0,492602,"synonymous_variant",0,0.47,{"v":1e-16,"d":"1.00E-16"},16,null,0.031,"[NR] unit increase","NR [NR] (imputed)","N"]
[6,"rs822928",1,234858597,"rs514230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-A","rs514230",0,514230,"intergenic_variant",1,0.476,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(Men + Women)",0.032,"[0.024-0.040] nmol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[25,"rs535772",9,15293116,"rs486349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9p22.3","NR","TTC39B",null,null,"ENSG00000155158",null,null,"rs486349-G","rs486349",0,486349,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.044,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Palmitoleic acid (16:1n-7) levels","3,521 Chinese ancestry individuals, European individuals (see Wu 2013).","NA","11q12.2","FADS1, FADS2","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.022,"[0.016-0.028] unit increase","Affymetrix, Illumina [~ 2200000] (imputed)","N"]
[33,"rs35350651",12,112486818,"rs17696736","2008-06-16",17554260,"Todd JA","2007-06-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/17554260","Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.","Type 1 diabetes","2,000 European ancestry cases, 3,000 European ancestry controls","2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls","12q24.13","C12orf30","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-G","rs17696736",0,17696736,"intron_variant",0,0.42,{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,1.22,"[1.15-1.28]","Affymetrix [NR]","N"]
[44,"rs58542926",19,19366632,"rs72999033","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"HAPLN4, AC138430.1, AC138430.2",null,null,"ENSG00000187664, ENSG00000267629, ENSG00000280282",null,null,"rs72999033-?","rs72999033",0,72999033,"3_prime_UTR_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2016-12-08",26830138,"Herold C","2016-02-02","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/26830138","Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.","Alzheimer disease and age of onset","2,478 European ancestry cases, 979 ancestry controls both from the same 1,070 families","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(between families)",null,null,"Affymetrix [up to 15107142] (imputed)","N"]
[46,"rs7246100",19,45436216,"rs7260330","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,1573,9279,"rs7260330-G","rs7260330",0,7260330,"intergenic_variant",1,0.39,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(RAC-beta serine/threonine-protein kinase, AKT2.14685.17.3)",0.24,"[0.18-0.3] unit increase","Affymetrix [10572788] (imputed)","N"]
[13,"rs56912706",5,75003678,"rs2307111","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.5474,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.023,"[0.018-0.028] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[19,"rs34121855",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.03656896,"[0.028-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.891,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(East Asian)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.48,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Triglycerides in very small VLDL)",0.09,"[0.07-0.11] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglycerides","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.245,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Filipino)",0.342,"unit increase","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[52,"rs372038686",23,109820068,"rs1573036","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","Xq23","TDGF3","TDGF1P3 - AL512882.1","ENSG00000225366","ENSG00000228042",null,53819,60001,"rs1573036-T","rs1573036",0,1573036,"intergenic_variant",1,0.031,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Men)",0.035,"[0.027-0.043] umol/L increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[13,"rs4704210",5,74808880,"rs4604177","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","5q13.3","HMGCR","POLK",null,null,"ENSG00000122008",null,null,"rs4604177-T","rs4604177",0,4604177,"intron_variant",0,0.53,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(BMI unadjusted)",0.081,"[0.061-0.101] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[34,"rs11065358",12,121414915,"rs2255531","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","12q24.31","HNF1A-AS1","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs2255531-A","rs2255531",0,2255531,"intron_variant",0,0.3495,{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.03117565,"[0.024-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[42,"rs4939883",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.1883,{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.03814463,"[0.029-0.047] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[20,"rs1461729",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(EA)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(Low-density lipoprotein receptor-related protein 1B, LRP1B.7640.29.3)",0.37,"[0.27-0.47] unit decrease","Affymetrix [10572788] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.875,{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(East Asian)",0.178,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs11065358",12,121416650,"rs1169288","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.31","NR","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,"NR",{"v":6e-16,"d":"6.00E-16"},15.2218487496163,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum alkaline phosphatase levels","105,030 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,null,0.03517,"[0.027-0.044] unit decrease novel","Illumina [6108953] (imputed)","N"]
[31,"rs651821",11,116639104,"rs10790162","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,null,0.39,"[0.29-0.49] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[19,"rs34121855",7,73042085,"rs62466318","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.2039,{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.03591725,"[0.027-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61623140,"rs174601","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q12.2","FADS1","FADS2",null,null,"ENSG00000134824",null,null,"rs174601-T","rs174601",0,174601,"non_coding_transcript_exon_variant",0,0.34,{"v":8e-16,"d":"8.00E-16"},15.096910013008,"(stearidonate (18:4n3))",0.034,"[0.026-0.042] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[37,"rs1077835",15,58723675,"rs1800588","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.38,{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,2.719,"[2.07-3.37] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[47,"rs8111874",19,49213504,"rs2452170","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2 - MAMSTR","ENSG00000176920","ENSG00000176909",null,4297,2495,"rs2452170-G","rs2452170",0,2452170,"intergenic_variant",1,0.497,{"v":9e-16,"d":"9.00E-16"},15.0457574905606,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Type 2 diabetes","approximately 459,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[18,"6:160560880_CATG_C",6,160578860,"rs1564348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs1564348-T","rs1564348",0,1564348,"intron_variant",0,0.838,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47796662,"rs11039391","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Suffering from nerves","369,499 European ancestry individuals","NA","11p11.2","NR","FNBP4 - NUP160","ENSG00000109920","ENSG00000030066",null,7667,2977,"rs11039391-A","rs11039391",0,11039391,"intergenic_variant",1,0.339514,{"v":1e-15,"d":"1.00E-15"},15,null,7.98,"z score decrease","NR [10847151] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,"(Phosphatidylcholine with diacyl residue sum C32:0/Phosphatidylcholine with diacyl residue sum C34:3)",0.337497,"[0.26-0.42] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2018-09-14",27618452,"Ehret GB","2016-09-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618452","The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.","Systolic blood pressure","up to 201,529 European ancestry individuals","up to 140,886 European ancestry individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.475,{"v":1e-15,"d":"1.00E-15"},15,null,0.498,"[0.38-0.62] mm Hg increase","Affymetrix, Illumina, Perlegen [128272]","N"]
[44,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.177,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Hispanic)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs6908402",6,26267755,"rs7773004","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference adjusted for body mass index","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p22.2","HIST1H3G, HIST1H2BH","HIST1H2BH - HIST1H3G","ENSG00000275713","ENSG00000273983",null,13817,1878,"rs7773004-A","rs7773004",0,7773004,"intergenic_variant",1,0.5045,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.0263,"[0.02-0.033] unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,0.917,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Hispanic)",0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs58065809",11,117002403,"rs6589598","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","PCSK7","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,12506,3841,"rs6589598-G","rs6589598",0,6589598,"intergenic_variant",1,0.77765625,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(TFRC)",0.22989437,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[32,"rs11282820",12,109879292,"rs11608355","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","12q24.11","NR","MYO1H",null,null,"ENSG00000174527",null,null,"rs11608355-T","rs11608355",0,11608355,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,7.943,"z score decrease","Affymetrix [10847151] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.168,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.15,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[47,"rs8111874",19,49206417,"rs492602","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-A","rs492602",0,492602,"synonymous_variant",0,0.518,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206985,"rs602662","2013-09-05",19744961,"Hazra A","2009-09-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/19744961","Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.","Folate pathway vitamin levels","3,305 European ancestry females, 1,458 European ancestry males","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs602662-?","rs602662",0,602662,"missense_variant",0,0.44,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Plasma Vitamin B12)",0.07,"[0.050-0.090] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1461729",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.056,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61589481,"rs28456","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs28456-G","rs28456",0,28456,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(Phosphatidylcholine with diacyl residue sum C42:1/Phosphatidylcholine with acyl-alkyl residue sum C36:2)",0.350198,"[0.26-0.44] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[31,"rs651821",11,116639104,"rs10790162","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.38,"[0.28-0.48] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs615632",8,10190040,"rs7832708","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs7832708-C","rs7832708",0,7832708,"intron_variant",0,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,null,0.013677,"[0.01-0.017] unit decrease","Affymetrix [18485882] (imputed)","N"]
[30,"rs174564",11,61581764,"rs174560","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174560-C","rs174560",0,174560,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(Phosphatidylcholine with diacyl residue sum C40:5/Lysophosphatidylcholine with acyl residue C20:3)",0.348537,"[0.26-0.43] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs688359",6,160465291,"rs688359","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q25.3","IGF2R","IGF2R",null,null,"ENSG00000197081",null,null,"rs688359-A","rs688359",0,688359,"intron_variant",0,0.6112,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.0526,"[0.039-0.066] unit decrease","NR [8041861] (imputed)","N"]
[30,"rs174564",11,61571348,"rs174548","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174548-C","rs174548",0,174548,"5_prime_UTR_variant",0,0.7049,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(Cis/trans-18:2, EA)",0.0035,"[0.0027-0.0043] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.885,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(Hispanic)",0.186,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45424351,"rs814573","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,1745,5710,"rs814573-T","rs814573",0,814573,"intergenic_variant",1,0.198,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(Apolipoprotein E (isoform E2), APOE.5312.49.3)",0.25,"[0.19-0.31] unit increase","Affymetrix [10572788] (imputed)","N"]
[28,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.03014323,"[0.023-0.038] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,0.776,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(Neogenin, NEO1.8900.28.3)",0.23,"[0.17-0.29] unit decrease","Affymetrix [10572788] (imputed)","N"]
[27,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(EA, Intercellular adhesion molecule 2)",0.4016,"[0.3-0.5] unit decrease","Affymetrix [509946]","N"]
[30,"rs174564",11,61570783,"rs174547","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-C","rs174547",0,174547,"intron_variant",0,0.3261,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,1.8519754,"[1.39-2.32] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[8,"rs693",2,21244000,"rs10199768","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs10199768-T","rs10199768",0,10199768,"intron_variant",0,0.47,{"v":8e-15,"d":"8.00E-15"},14.096910013008,"(LDL)",0.11,"[0.083-0.137] mmol/l increase","Illumina [NR] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.86,{"v":8e-15,"d":"8.00E-15"},14.096910013008,"(X-03094)",0.025,"[0.019-0.031] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73052057,"rs799165","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,13184,30098,"rs799165-?","rs799165",0,799165,"intergenic_variant",1,"NR",{"v":9e-15,"d":"9.00E-15"},14.0457574905606,{"$nulls":3},"Affymetrix [NR]","N"]
[24,"rs2954021",8,126482077,"rs2954021","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte percentage of white cells","171,748 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5053,{"v":9e-15,"d":"9.00E-15"},14.0457574905606,null,0.02756497,"[0.021-0.035] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-07-24",26192919,"Liu JZ","2015-07-20","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26192919","Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.","Inflammatory bowel disease","12,882 European ancestry cases, 21,770 European ancestry controls","25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-A","rs1260326",0,1260326,"missense_variant",0,0.4059,{"v":1E-14,"d":"1.00E-14"},14,"(EA)",1.080162,"[1.06-1.1]","Affymetrix, Illumina [~ 9000000] (imputed)","N"]
[18,"6:160560880_CATG_C",6,160578860,"rs1564348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs1564348-T","rs1564348",0,1564348,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,null,0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Balding type 1","approximately 208,000 European ancestry individuals","NA","11q12.2",null,"FADS2",null,null,"ENSG00000134824",null,null,"rs1535-?","rs1535",0,1535,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[33,"rs35350651",12,111904371,"rs4766578","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5425,{"v":1E-14,"d":"1.00E-14"},14,null,0.0219,"[0.016-0.027] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[38,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.393,{"v":1E-14,"d":"1.00E-14"},14,"(EA)",0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.84,{"v":1E-14,"d":"1.00E-14"},14,null,0.066,"[0.048-0.084] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":1E-14,"d":"1.00E-14"},14,"(Deformed epidermal autoregulatory factor 1 homolog, DEAF1.6369.82.3)",0.2,"[0.14-0.26] unit increase","Affymetrix [10572788] (imputed)","N"]
[15,"rs6908402",6,26267755,"rs7773004","2019-02-26",30566020,"Fukaya E","2018-12-01","Circulation","www.ncbi.nlm.nih.gov/pubmed/30566020","Clinical and Genetic Determinants of Varicose Veins.","Varicose veins","9,577 British ancestry cases, 327,959 British ancestry controls","NA","6p22.2","NR","HIST1H2BH - HIST1H3G","ENSG00000275713","ENSG00000273983",null,13817,1878,"rs7773004-G","rs7773004",0,7773004,"intergenic_variant",1,0.49,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.113,"[0.084-0.142] unit decrease","Affymetrix [10972371] (imputed)","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.915,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(Hispanic)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","TMEM258","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(Phosphatidylcholine with acyl-alkyl residue sum C38:4/Sphingomyelin with acyl residue sum C24:0)",0.339909,"[0.25-0.43] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.39,"[0.29-0.49] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs1263151",11,116654435,"rs603446","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs603446-?","rs603446",0,603446,"intron_variant",0,null,{"v":2E-14,"d":"2.00E-14"},13.698970004336,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[33,"rs35350651",12,112486818,"rs17696736","2008-06-16",17554300,"Wellcome Trust Case Control Consortium","2007-06-07","Nature","www.ncbi.nlm.nih.gov/pubmed/17554300","Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.","Type 1 diabetes","1,963 European ancestry cases, 2,938 European ancestry controls","(see Todd 2007)","12q24.13","SH2B3, TRAFD1, PTPN11, LNK","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-G","rs17696736",0,17696736,"intron_variant",0,0.42,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,1.34,"[1.16-1.53]","Affymetrix [469557]","N"]
[46,"rs11556505",19,45395619,"rs2075650","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,0.15,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(LDL)",0.153,"[0.11-0.19] mmol/l increase","Illumina [NR] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(Pseudokinase FAM20A, FAM20A.6433.57.3)",0.35,"[0.25-0.45] unit increase","Affymetrix [10572788] (imputed)","N"]
[8,"rs6544366",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.34,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.13,"[0.09-0.17] unit increase","Affymetrix [389878]","N"]
[22,"rs287",8,19820405,"rs331","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs331-?","rs331",0,331,"intron_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(HDL-C.assay, fasting)",1.51,"[NR] unit increase","Illumina [335603]","N"]
[30,"rs174564",11,61549025,"rs174533","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","11q12.2","MYRF, TMEM258","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174533-A","rs174533",0,174533,"intron_variant",0,0.346,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.02827519,"[0.021-0.036] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61593816,"rs174568","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174568-T","rs174568",0,174568,"missense_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(Phosphatidylcholine with diacyl residue sum C38:0/Phosphatidylcholine with acyl-alkyl residue sum C38:6)",0.339,"[0.25-0.43] unit increase","Illumina [up to 9281895] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2009-05-19",19430479,"Levy D","2009-05-10","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19430479","Genome-wide association study of blood pressure and hypertension.","Diastolic blood pressure","29,136 European ancestry individuals","34,433 European ancestry individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.48,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.48,"[0.36-0.60] mm Hg increase","Affymetrix, Illumina [2533153] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(Interleukin-22 receptor subunit alpha-1, IL22RA1.3620.67.2)",0.35,"[0.25-0.45] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.178,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.147,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.175,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.148,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2409784",8,11433909,"rs2898290","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,null,{"v":4E-14,"d":"4.00E-14"},13.397940008672,null,0.294,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-A","rs174577",0,174577,"intron_variant",0,0.3431,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Cis/trans-18:2, EA)",0.0032,"[0.0024-0.004] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[52,"rs372038686",23,109820068,"rs1573036","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","Xq23","TDGF3","TDGF1P3 - AL512882.1","ENSG00000225366","ENSG00000228042",null,53819,60001,"rs1573036-T","rs1573036",0,1573036,"intergenic_variant",1,0.031,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Men + Women)",0.028,"[0.021-0.035] umol/L increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs73600084",8,19843171,"rs17091891","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","8p21.3","intergenic","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,18401,93454,"rs17091891-T","rs17091891",0,17091891,"intergenic_variant",1,0.8709,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,null,0.0585,"[0.043-0.074] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-A","rs1535",0,1535,"intron_variant",0,0.6659,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(Cis/trans-18:2, EA)",0.0032,"[0.0024-0.004] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[4,"rs1183851",1,62902874,"rs646179","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","1p31.3",null,"USP1",null,null,"ENSG00000162607",null,null,"rs646179-?","rs646179",0,646179,"5_prime_UTR_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61571348,"rs174548","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174548-G","rs174548",0,174548,"5_prime_UTR_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(Phosphatidylcholine with acyl-alkyl residue sum C36:3/Sphingomyelin with acyl residue sum C16:0)",0.335386,"[0.25-0.42] unit increase","Illumina [up to 9281895] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(APOA1.assay, whole)",2.529,"[NR] unit decrease","Illumina [335603]","N"]
[46,"rs11556505",19,45395619,"rs2075650","2016-12-13",26993346,"Schott JM","2016-03-15","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/26993346","Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.","Posterior cortical atrophy and Alzheimer's disease","293 cases, 10,547 healthy controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,null,2.03167,"[1.67959-2.45755]","Illumina [~ 5900000] (imputed)","N"]
[46,"rs2238681",19,45401666,"rs8106922","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs8106922-A","rs8106922",0,8106922,"intron_variant",0,0.618134,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(females)",1.62673,"[1.43-1.82]","Affymetrix, Illumina [2928658] (imputed)","N"]
[30,"rs174564",11,61552680,"rs174537","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174537-T","rs174537",0,174537,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(Phosphatidylcholine with acyl-alkyl residue sum C40:5/Phosphatidylcholine with acyl-alkyl residue sum C44:4)",0.32504,"[0.24-0.41] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[30,"rs174564",11,61579760,"rs174555","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum neutrophil eosinophil counts","170,384 European ancestry individuals","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174555-C","rs174555",0,174555,"intron_variant",0,0.3085,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,null,0.028962,"[0.021-0.037] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[19,"rs34121855",7,73010442,"rs13247874","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13247874-?","rs13247874",0,13247874,"intron_variant",0,"NR",{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(VLDL-D)",0.16,"[0.12-0.2] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[21,"rs11250098",8,10802146,"rs12546366","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (arm fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs12546366-T","rs12546366",0,12546366,"intron_variant",0,0.4529,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(females)",0.0212,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[31,"rs11600380",11,116665079,"rs9804646","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-C","rs9804646",0,9804646,"intergenic_variant",1,0.793,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(East Asian)",0.125,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs73600084",8,19830921,"rs10096633","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,6151,105704,"rs10096633-T","rs10096633",0,10096633,"regulatory_region_variant",1,0.12,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,null,0.169,"[0.12-0.21] unit decrease","Illumina [561583]","N"]
[22,"rs7816447",8,19832646,"rs17482753","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,7876,103979,"rs17482753-G","rs17482753",0,17482753,"regulatory_region_variant",1,0.891,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,"(East Asian)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[44,"19:19510831_AT_A",19,19591066,"rs10401193","2015-09-24",25282103,"Wood AR","2014-10-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25282103","Defining the role of common variation in the genomic and biological architecture of adult human height.","Height","253,288 European ancestry individuals","80,067 European ancestry individuals","19p13.11","GATAD2A","GATAD2A",null,null,"ENSG00000167491",null,null,"rs10401193-A","rs10401193",0,10401193,"intron_variant",0,0.819,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,null,0.028,"[0.02-0.036] unit increase","Affymetrix, Illumina, Perlegen [2550858] (imputed)","N"]
[6,"rs822928",1,234851216,"rs496800","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6",null,null,"ENSG00000282097",null,null,"rs496800-A","rs496800",0,496800,"intron_variant",0,0.477,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs3817588",2,27743154,"rs780092","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-G","rs780092",0,780092,"intron_variant",0,0.1428,{"v":1E-13,"d":"1.00E-13"},13,null,5.2217927,"[3.84-6.61] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72911843,"rs13244268","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","7q11.23","BAZ1B","BAZ1B",null,null,"ENSG00000009954",null,null,"rs13244268-T","rs13244268",0,13244268,"intron_variant",0,"NR",{"v":1E-13,"d":"1.00E-13"},13,{"$nulls":3},"NR [2501543] (imputed)","N"]
[26,"rs3824477",9,107588328,"rs3824477","2018-08-16",27668658,"Iotchkova V","2016-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27668658","Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.","Cardiometabolic and hematological traits","up to 35,981 European ancestry individuals","up to 102,505 European ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs3824477-A","rs3824477",0,3824477,"intron_variant",0,null,{"v":1E-13,"d":"1.00E-13"},13,"(HDL)",0.026,"[-0.21312-0.26512] unit increase","Affymetrix, Illumina [17000000] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-G","rs1535",0,1535,"intron_variant",0,"NR",{"v":1E-13,"d":"1.00E-13"},13,"(Phosphatidylcholine with acyl-alkyl residue sum C34:2/Phosphatidylcholine with acyl-alkyl residue sum C44:6)",0.321785,"[0.24-0.41] unit increase","Illumina [up to 9281895] (imputed)","N"]
[44,"rs3761077",19,19336608,"rs2238675","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.887,{"v":1E-13,"d":"1.00E-13"},13,"(Hispanic)",0.164,"[0.12-0.21] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[46,"rs62117206",19,45247627,"rs4803750","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-?","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":1E-13,"d":"1.00E-13"},13,{"$nulls":3},"Affymetrix [NR]","N"]
[47,"rs8111874",19,49206172,"rs516246","2016-07-24",26192919,"Liu JZ","2015-07-20","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26192919","Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.","Inflammatory bowel disease","12,882 European ancestry cases, 21,770 European ancestry controls","25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-A","rs516246",0,516246,"intron_variant",0,0.4652,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",1.0784879,"[1.06-1.1]","Affymetrix, Illumina [~ 9000000] (imputed)","N"]
[8,"rs6544366",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs253412",5,75015242,"rs2112347","2010-11-17",20935630,"Speliotes EK","2010-10-10","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20935630","Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.","Body mass index","Up to 123,865 European ancestry individuals","Up to 125,931 European ancestry individuals","5q13.3","FLJ35779, HMGCR","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.63,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.1,"[0.06-0.14] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2800000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2017-03-14",27599772,"Ram R","2016-09-07","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/27599772","A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.","Hypertriglyceridemia","927 Saudi Arabian ancestry cases, 3,159 Saudi Arabian ancestry controls","317 Saudi Arabian ancestry cases, 1,098 Saudi Arabian ancestry controls","7q11.23","TBL2, MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,1.82,"[1.41-2.38]","Affymetrix [~ 8000000] (imputed)","N"]
[25,"rs535772",9,15296034,"rs643531","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9p22.3","NR","TTC39B",null,null,"ENSG00000155158",null,null,"rs643531-C","rs643531",0,643531,"intron_variant",0,0.137,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA)",0.04,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs2072114",11,61603358,"rs2727271","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Non-albumin protein levels","98,538 Japanese ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs2727271-?","rs2727271",0,2727271,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.03693,"[0.027-0.047] unit increase novel","Illumina [6108953] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8665,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.03873643,"[0.028-0.049] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8775,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(NXPH2)",0.27592963,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[33,"rs35350651",12,111910219,"rs10774625","2010-12-16",21060863,"Ikram MK","2010-10-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21060863","Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.","Retinal vascular caliber","15,358 European ancestry individuals","6,652 European ancestry individuals","12q24.12","SH2B3, ATXN2, PTPN11","ATXN2",null,null,"ENSG00000204842",null,null,"rs10774625-A","rs10774625",0,10774625,"intron_variant",0,0.48,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(Retinal venular caliber)",1.5,"[1.11-1.89] um increase","Affymetrix, Illumina [2194468] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.041,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC1, CTB-129P6.7","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.1730382,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA, Apolipoprotein E (isoform E2))",0.4193,"[0.31-0.53] unit increase","Affymetrix [509946]","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":2e-13,"d":"2.00E-13"},12.698970004336,{"$nulls":3},"Illumina [563980]","N"]
[13,"rs253412",5,75015242,"rs2112347","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","5q13.3","POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.631,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(EA, women)",0.03,"[0.022-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[20,"rs1461729",8,9183358,"rs9987289","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.069,"[0.05-0.09] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.44,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Asian initial, BMI unadjusted)",0.064,"[0.046-0.082] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[30,"rs174564",11,61551356,"rs174535","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Respiratory diseases","approximately 459,000 European ancestry individuals","NA","11q12.2",null,"TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174535-?","rs174535",0,174535,"synonymous_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2018-10-24",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglyceride levels","1,017 Yoruban ancestry individuals, 1,765 Filipino individuals","188,577 European and other ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Filipino)",null,null,"Illumina [4454201] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-G","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(BP-HDLC)",0.29,"[0.21-0.37] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-11-01",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","LDL cholesterol levels","2,601 European ancestry type 2 diabetes cases and controls","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.22,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,2.1,"(% variance) increase","Affymetrix [389878]","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs615632",8,9804292,"rs9650622","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","8p23.1","LOC105379235, MIR124-1","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,41416,103703,"rs9650622-T","rs9650622",0,9650622,"intergenic_variant",1,0.53,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[30,"rs174564",11,61565908,"rs174541","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174541-T","rs174541",0,174541,"intron_variant",0,0.6495,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(Cis/trans-18:2, EA)",0.0031,"[0.0023-0.0039] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5177,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,0.0259686,"[0.019-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2014-11-13",24770881,"Nelson PT","2014-04-27","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/24770881","ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.","Alzheimer's disease","1443 cases and 99 controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":4e-13,"d":"4.00E-13"},12.397940008672,{"$nulls":3},"NR [4913579] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.928632,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,2.214072,"[1.79-2.64]","Affymetrix, Illumina [2928658] (imputed)","N"]
[22,"rs7816447",8,19860460,"rs79236614","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-C","rs79236614",0,79236614,"intergenic_variant",1,0.916,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Hispanic)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19912370,"rs115849089","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,87600,24255,"rs115849089-G","rs115849089",0,115849089,"intergenic_variant",1,0.904,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Hispanic)",0.153,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61581764,"rs174560","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite ratios in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174560-C","rs174560",0,174560,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Phosphatidylcholine with diacyl residue sum C34:2/Phosphatidylcholine with diacyl residue sum C42:1)",0.324237,"[0.24-0.41] unit increase","Illumina [up to 9281895] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.869,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Apolipoprotein A-V, APOA5.11318.20.3)",0.26,"[0.18-0.34] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.308,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(Hispanic)",0.117,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs74410908",2,21250914,"rs679899","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs679899-G","rs679899",0,679899,"missense_variant",0,0.503125,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(LRP1B)",0.1736701,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin concentration","172,851 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8665,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,0.03660462,"[0.027-0.047] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-08-16",29899525,"Klimentidis YC","2018-06-13","Int J Obes (Lond)","www.ncbi.nlm.nih.gov/pubmed/29899525","Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE.","Moderate to vigorous physical activity levels","377,234 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,0.022,"unit decrease","Affymetrix [11800000] (imputed)","N"]
[11,"rs3770586",2,169830328,"rs2287622","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2q31.1","ABCB11","ABCB11, ABCB11",null,null,"ENSG00000073734, ENSG00000276582",null,null,"rs2287622-A","rs2287622",0,2287622,"missense_variant",0,0.405,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(Trans-ethnic initial)",0.0266,"[0.02-0.034] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[13,"rs7700719",5,74262162,"rs4703642","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","5q13.3","GCNT4","AC116337.3",null,null,"ENSG00000249856",null,null,"rs4703642-A","rs4703642",0,4703642,"intron_variant",0,"NR",{"v":7e-13,"d":"7.00E-13"},12.1549019599857,{"$nulls":3},"NR [2501549] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.78,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(BMI unadjusted)",0.082,"[0.06-0.104] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Palmitoleic acid (16:1n-7) levels","8,961 European ancestry individuals",null,"11q12.2","C11orf0, C11orf9, FADS1, FADS2, FEN1","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-T","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.329,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,0.024,"[0.017-0.03] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(Apolipoprotein L1, APOL1.9506.10.3)",0.18,"[0.12-0.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[47,"rs8111874",19,49206417,"rs492602","2017-07-13",28537254,"Tsoi LC","2017-05-24","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28537254","Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.","Psoriasis","Up to 11,988 European ancestry cases, up to 275,335 European ancestry controls","7,044 European ancestry cases, 11,434 European ancestry controls","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-G","rs492602",0,492602,"synonymous_variant",0,0.46,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,1.11,null,"Illumina, Perlegen [9113515] (imputed)","N"]
[24,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":8e-13,"d":"8.00E-13"},12.096910013008,"(BMI unadjusted)",0.07,"[0.05-0.09] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[26,"rs13284054",9,107657070,"rs3905000","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-G","rs3905000",0,3905000,"intron_variant",0,0.86,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,0.11,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[38,"rs247617",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-T","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,1.45,"[1.06-1.84] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-?","rs5167",0,5167,"missense_variant",0,"NR",{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,0.03734,"[0.027-0.048] unit decrease novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,"(male)",0.25305,"[0.18-0.32] unit increase","Affymetrix [7794483] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.04,{"v":1e-12,"d":"1.00E-12"},12,"(VLDL diameter)",0.2,"[0.14-0.26] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[19,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs615632",8,9803712,"rs13271489","2018-09-05",29455858,"Sung YJ","2018-02-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29455858","A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.","Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)","43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers","139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers","8p23.1","MIR124-1, MSRA","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,40836,104283,"rs13271489-?","rs13271489",0,13271489,"intergenic_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,"(EA)",null,null,"Affymetrix, Illumina [18800000] (imputed)","N"]
[21,"rs2409784",8,11376266,"rs2618451","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","BLK","BLK",null,null,"ENSG00000136573",null,null,"rs2618451-T","rs2618451",0,2618451,"intron_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.012487,"[0.0091-0.0159] unit decrease","Affymetrix [18485882] (imputed)","N"]
[30,"rs174564",11,61546592,"rs174530","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum total protein level","113,509 Japanese ancestry individuals","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174530-?","rs174530",0,174530,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.03134,"[0.023-0.04] unit increase novel","Illumina [6108953] (imputed)","N"]
[30,"rs174471",11,61663691,"rs174468","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)","8,866 European ancestry individuals","NA","11q12.2","RAB3IL1","FADS3 - RAB3IL1","ENSG00000221968","ENSG00000167994",null,4168,1082,"rs174468-A","rs174468",0,174468,"regulatory_region_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.01,"[NR] % decrease","Affymetrix, Illumina [NR]","N"]
[31,"rs964184",11,116648917,"rs964184","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1e-12,"d":"1.00E-12"},12,null,0.17,"[0.11-0.23] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","16q13","HERPUD1, CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-?","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.03734,"[0.027-0.048] unit decrease novel","Illumina [6108953] (imputed)","N"]
[44,"rs58542926",19,19379549,"rs58542926","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.079,{"v":1e-12,"d":"1.00E-12"},12,null,1.09,"[1.06-1.12]","Affymetrix, Illumina [247470]","N"]
[46,"rs1065853",19,45415640,"rs445925","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity (ABCA-1 dependent assay)","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","19q13.32","APOE/C1/C2/C4","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-G","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.886,{"v":1e-12,"d":"1.00E-12"},12,null,0.2155,"[0.16-0.27] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","LDL cholesterol","4,763 Northern Finnish founder individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.21,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.16,"[0.11-0.20] mmol/l decrease","Illumina [329091]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2015-11-07",25646370,"Matsuo H","2015-02-02","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/25646370","Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.","Gout","945 Japanese ancestry cases, 1,213 Japanese ancestry controls","1,048 Japanese ancestry cases, 1,334 Japanese ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.55,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,1.36,"[1.25-1.48]","Illumina [570442]","N"]
[13,"rs253412",5,74991849,"rs6881648","2017-10-27",28892062,"Akiyama M","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892062","Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.","Body mass index","up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men","up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs6881648-C","rs6881648",0,6881648,"intron_variant",0,0.56,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Japanese)",0.024,"[0.018-0.03] kg/m2 decrease","Illumina [6108953] (imputed)","N"]
[18,"rs641990",6,160774486,"rs487152","2017-10-27",28892062,"Akiyama M","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892062","Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.","Body mass index","up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men","up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls","6q25.3","SLC22A3","SLC22A3",null,null,"ENSG00000146477",null,null,"rs487152-A","rs487152",0,487152,"intron_variant",0,0.49,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.017,"[0.013-0.021] kg/m2 increase","Illumina [6108953] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or ischemic stroke","12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls","NA","6q25.3","SLC22A3, LPAL2, LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-?","rs10455872",0,10455872,"intron_variant",0,null,{"v":2E-12,"d":"2.00E-12"},11.698970004336,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of white cells","171,542 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5053,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.02513768,"[0.018-0.032] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61551356,"rs174535","2015-07-27",25500335,"Tintle NL","2014-12-02","Prostaglandins Leukot Essent Fatty Acids","www.ncbi.nlm.nih.gov/pubmed/25500335","A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study.","Red blood cell fatty acid levels","2,633 individuals","NA","11q12.2","C11orf9, C11orf10, FADS2, FADS1, FEN1","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174535-?","rs174535",0,174535,"synonymous_variant",0,0.33,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(OA)",0.138,"[NR] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,112059557,"rs11065979","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","12q24.12","BRAP","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.438,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(Platelet glycoprotein Ib alpha chain, GP1BA.4990.87.1)",0.17,"[0.13-0.21] unit increase","Affymetrix [10572788] (imputed)","N"]
[33,"rs35350651",12,112059557,"rs11065979","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","12q24.12","NR","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-C","rs11065979",0,11065979,"intergenic_variant",1,0.562141,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.0158643,"[0.011-0.02] unit decrease","Affymetrix [11535925] (imputed)","N"]
[37,"rs1077835",15,58730498,"rs588136","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","15q21.3","LIPC","LIPC-AS1, ALDH1A2, LIPC",null,null,"ENSG00000259293, ENSG00000128918, ENSG00000166035",null,null,"rs588136-?","rs588136",0,588136,"intron_variant",0,0.69,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(HDL-C)",0.05,"[0.030-0.070] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[43,"rs576249617",19,11227326,"rs2738446","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Metabolite levels","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs2738446-C","rs2738446",0,2738446,"intron_variant",0,0.14,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(LDL)",2.9507,"[2.13-3.77] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[11,"rs3770586",2,169830798,"rs10177080","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2q31.1","ABCB11","ABCB11, ABCB11",null,null,"ENSG00000073734, ENSG00000276582",null,null,"rs10177080-A","rs10177080",0,10177080,"intron_variant",0,0.5435,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.0189,"[0.014-0.024] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[13,"rs56912706",5,75003678,"rs2307111","2013-09-12",23563607,"Berndt SI","2013-04-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23563607","Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.","Obesity","93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls","65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls","5q13.3","C5orf37","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.6,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(Obesity class I)",1.07,"[NR]","Affymetrix, Illumina [~ 2800000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73012042,"rs35332062","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-?","rs35332062",0,35332062,"missense_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.22857,"[0.16-0.29] unit increase","Affymetrix [7794483] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","9q31.1",null,"ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-?","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2012-06-18",22437554,"Major JM","2012-03-21","J Nutr","www.ncbi.nlm.nih.gov/pubmed/22437554","Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.","Response to Vitamin E supplementation","2,112 European ancestry individuals","NA","11q23.3","ZNF259, LOC100128347, APOA5, SIK3, BUD13","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.15,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(alpha-TOH)",0.07,"[0.050-0.090] mg/L increase","Illumina [549989]","N"]
[31,"rs964184",11,116648917,"rs964184","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","11q23.3","APOC, APOA","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(Hispanic)",0.0459,"[NR] unit decrease","Affymetrix [NR]","N"]
[37,"rs261290",15,58678512,"rs10468017","2011-06-29",21665990,"Yu Y","2011-06-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21665990","Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.","Age-related macular degeneration","2,594 European ancestry cases, 4,134 European ancestry controls","5,640 European ancestry cases, 52,174 European ancestry controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-?","rs10468017",0,10468017,"intron_variant",0,0.71,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,1.19,"[NR]","Affymetrix [6036699] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2017-10-02",28800603,"Arpawong TE","2017-08-11","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28800603","Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort.","Verbal memory performance (residualized delayed recall level)","7,486 European ancestry individuals aged 50 years or older","6,898 European ancestry individuals aged 50 years or older","19q13.32","TOMM40, APOE, PVRL2","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,null,"unit decrease","Illumina [at least 1198956] (imputed)","N"]
[12,"rs59950280",4,3452345,"rs59950280","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4p16.3","intergenic","HGFAC - DOK7","ENSG00000109758","ENSG00000175920",null,1123,12693,"rs59950280-A","rs59950280",0,59950280,"intergenic_variant",1,0.3883,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0198,"[0.014-0.025] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[13,"rs4704210",5,74625487,"rs7703051","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-?","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[22,"rs11986942",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.803,{"v":4e-12,"d":"4.00E-12"},11.397940008672,"(East Asian)",0.126,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil count","170,702 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5176,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.02475963,"[0.018-0.032] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,111973358,"rs597808","2019-01-14",30367059,"Teumer A","2018-10-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30367059","Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.","Hypothyroidism","3,340 European ancestry cases, 49,983 European ancestry controls","NA","12q24.12","ATXN2/SH2B3","ATXN2",null,null,"ENSG00000204842",null,null,"rs597808-A","rs597808",0,597808,"intron_variant",0,0.51,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.18,"[0.13-0.23] unit increase","Affymetrix, Illumina [5965951] (imputed)","N"]
[46,"rs11556505",19,45387459,"rs12972156","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs12972156-G","rs12972156",0,12972156,"intron_variant",0,0.13,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.17,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[21,"rs11250098",8,10763655,"rs4326350","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Smoking initiation (ever regular vs never regular)","up to 1,232,091 European ancestry individuals","NA","8p23.1","NR","XKR6",null,null,"ENSG00000171044",null,null,"rs4326350-G","rs4326350",0,4326350,"intron_variant",0,0.493,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,0.017613662,"[0.013-0.023] unit decrease","NR [~ 10000000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-A","rs7124681",0,7124681,"intron_variant",0,0.4117,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,"(EA)",0.0262,"[0.019-0.034] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.4106,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,"(EA)",0.0258,"[0.019-0.033] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.231,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,"(Hispanic)",0.121,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs3817588",2,27731212,"rs3817588","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs3817588-T","rs3817588",0,3817588,"intron_variant",0,"NR",{"v":6e-12,"d":"6.00E-12"},11.2218487496163,{"$nulls":3},"NR [2501749] (imputed)","N"]
[21,"rs1692821",8,11707174,"rs2740594","2017-10-24",28892059,"Chang D","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892059","A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.","Parkinson's disease","20,184 European ancestry cases, 397,324 European ancestry controls","5,851 European ancestry cases, 5,866 European ancestry controls","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs2740594-A","rs2740594",0,2740594,"intron_variant",0,0.753,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,null,1.09,"[1.07-1.12]","Illumina [11933700] (imputed)","N"]
[33,"rs35350651",12,112486818,"rs17696736","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.13","NAA25","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,0.6,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(AA, EA, Hispanic)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[43,"rs56322906",19,11341029,"rs1865063","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","19p13.2","ANGPTL8","DOCK6",null,null,"ENSG00000130158",null,null,"rs1865063-T","rs1865063",0,1865063,"intron_variant",0,0.26,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(BMI adjusted)",0.0632,"[0.046-0.08] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[24,"rs2954021",8,126479315,"rs6982636","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982636-?","rs6982636",0,6982636,"intron_variant",0,"NR",{"v":7e-12,"d":"7.00E-12"},11.1549019599857,"(APOB.assay, whole)",1.95,"[NR] unit decrease","Illumina [335603]","N"]
[34,"rs11065358",12,121416650,"rs1169288","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.31","NR","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.669,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,"(EA)",0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs289713",16,57002732,"rs9939224","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs9939224-G","rs9939224",0,9939224,"intron_variant",0,0.46,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,"(HDLC-GLUC)",0.31,"[0.21-0.41] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[12,"rs13108218",4,3443931,"rs13108218","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","4p16.3",null,"HGFAC",null,null,"ENSG00000109758",null,null,"rs13108218-?","rs13108218",0,13108218,"intron_variant",0,"NR",{"v":8e-12,"d":"8.00E-12"},11.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2015-05-12",21729881,"Major JM","2011-07-05","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21729881","Genome-wide association study identifies common variants associated with circulating vitamin E levels.","Vitamin E levels","2,402 European ancestry cases, 1612 European ancestry controls","475 European ancestry cases, 517 European ancestry controls, 1,416 cases, 1,359 controls","11q23.3","ZNF259, APOA5, BUD13","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.15,{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,0.04,"[0.02-0.06] unit increase","Illumina [NR]","N"]
[37,"rs1077835",15,58730498,"rs588136","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","15q21.3","LIPC","LIPC-AS1, ALDH1A2, LIPC",null,null,"ENSG00000259293, ENSG00000128918, ENSG00000166035",null,null,"rs588136-T","rs588136",0,588136,"intron_variant",0,0.8,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(1-stearoylglycerophosphoethanolamine)",0.029,"[0.021-0.037] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[6,"rs822928",1,234858597,"rs514230","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1q42.3","IRF2BP2","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-A","rs514230",0,514230,"intergenic_variant",1,0.48,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,0.036,"[NR] unit decrease","NR [NR] (imputed)","N"]
[13,"rs4704210",5,74625487,"rs7703051","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-?","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":9e-12,"d":"9.00E-12"},11.0457574905606,{"$nulls":3},"Affymetrix [NR]","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs822928",1,234858597,"rs514230","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1q42.3","IRF2BP2","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-T","rs514230",0,514230,"intergenic_variant",1,0.54,{"v":1e-11,"d":"1.00E-11"},11,null,0.041,"[0.029-0.053] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[12,"rs6818397",4,3434885,"rs6818397","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","4p16.3","LRPAP1","RGS12",null,null,"ENSG00000159788",null,null,"rs6818397-T","rs6818397",0,6818397,"intron_variant",0,0.413,{"v":1e-11,"d":"1.00E-11"},11,"(Trans-ethnic initial)",0.0254,"[0.018-0.033] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[14,"rs6882345",5,156398169,"rs1501908","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,0.37,{"v":1e-11,"d":"1.00E-11"},11,null,0.07,"[0.03-0.11] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[19,"rs34121855",7,72857049,"rs1178977","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs1178977-A","rs1178977",0,1178977,"splice_region_variant",0,0.89,{"v":1e-11,"d":"1.00E-11"},11,"(BMI unadjusted)",0.122,"[0.087-0.157] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,0.28,{"v":1e-11,"d":"1.00E-11"},11,"(Hb)",0.089,"[0.064-0.114] unit decrease","Illumina [561583]","N"]
[27,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":1e-11,"d":"1.00E-11"},11,"(Insulin-like growth factor 1 receptor, IGF1R.4232.19.2)",0.22,"[0.16-0.28] unit decrease","Affymetrix [10572788] (imputed)","N"]
[29,"11:47650138_AT_A",11,47796062,"rs11039389","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","11p11.2","intergenic","FNBP4 - NUP160","ENSG00000109920","ENSG00000030066",null,7067,3577,"rs11039389-T","rs11039389",0,11039389,"intergenic_variant",1,0.65857,{"v":1e-11,"d":"1.00E-11"},11,null,6.781,"z score increase","Illumina [18485882] (imputed)","N"]
[30,"rs174564",11,61609750,"rs174583","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-C","rs174583",0,174583,"intron_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112072424,"rs11065987","2009-11-03",19862010,"Ganesh SK","2009-10-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19862010","Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.","Hemoglobin","24,167 European ancestry individuals","9,456 European ancestry individuals","12q24.12","TRAFD1","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-A","rs11065987",0,11065987,"intergenic_variant",1,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.06,"[0.04-0.08] g/dl increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[38,"rs247617",16,56989590,"rs247616","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.32,{"v":1e-11,"d":"1.00E-11"},11,"(X-11550)",0.01,"[0.008-0.012] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[46,"rs157592",19,45424351,"rs814573","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,1745,5710,"rs814573-T","rs814573",0,814573,"intergenic_variant",1,0.198,{"v":1e-11,"d":"1.00E-11"},11,"(C-reactive protein, CRP.4337.49.2)",0.21,"[0.15-0.27] unit decrease","Affymetrix [10572788] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p31.3","ANGPTL3, DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.67,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.043,"[0.031-0.055] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.196,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(Hispanic)",0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs7700719",5,74262162,"rs4703642","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","5q13.3","GCNT4","AC116337.3",null,null,"ENSG00000249856",null,null,"rs4703642-A","rs4703642",0,4703642,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,{"$nulls":3},"NR [2501749] (imputed)","N"]
[19,"rs34121855",7,73017005,"rs13226650","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13226650-A","rs13226650",0,13226650,"intron_variant",0,0.83,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(TG)",0.12,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[26,"rs2740488",9,107665739,"rs2575876","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2575876-?","rs2575876",0,2575876,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(Tot-C/Est-C)",0.14,"[0.1-0.18] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47807774,"rs2290850","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Positive affect","410,603 European ancestry individuals","NA","11p11.2","NR","NUP160",null,null,"ENSG00000030066",null,null,"rs2290850-C","rs2290850",0,2290850,"intron_variant",0,0.3482479222397,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.008333924,"[0.0059-0.0108] unit decrease","NR [NR]","N"]
[29,"11:47650138_AT_A",11,47932666,"rs12802244","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","11p11.2","intergenic","AC023232.1 - PTPRJ","ENSG00000254780","ENSG00000149177",null,5507,69444,"rs12802244-A","rs12802244",0,12802244,"intergenic_variant",1,0.36027,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,6.708,"z score decrease","Illumina [18485882] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.12,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.03,"[0.02-0.04] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.495,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA)",0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-G","rs4939883",0,4939883,"intergenic_variant",1,0.83,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[44,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.01434,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.059,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.0714,"[0.05-0.092] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of white cells","171,542 European ancestry individuals","NA","8p23.1","RP11-115J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.9084,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.04101722,"[0.029-0.053] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[22,"rs301",8,19816934,"rs301","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs301-C","rs301",0,301,"intron_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(HDLC-WC)",0.22,"[0.16-0.28] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47807774,"rs2290850","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Depressive symptoms","1,067,913 European ancestry individuals","228,033 European ancestry individuals","11p11.2","NR","NUP160",null,null,"ENSG00000030066",null,null,"rs2290850-C","rs2290850",0,2290850,"intron_variant",0,0.3482479222397,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,6.8925936E-3,"[0.0049-0.0089] unit decrease","NR [NR]","N"]
[30,"rs174564",11,61623140,"rs174601","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174601-C","rs174601",0,174601,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs90192",11,116772441,"rs1076485","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (MTAG)","1,311,438 European ancestry individuals","NA","11q23.3","Intergenic","SIK3",null,null,"ENSG00000160584",null,null,"rs1076485-T","rs1076485",0,1076485,"intron_variant",0,0.1329,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(MTAG)",0.0129,"[0.0092-0.0166] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","12q24.12","SH2B3","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-C","rs653178",0,653178,"intron_variant",0,0.44,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,1.08,"[1.06-1.1]","Affymetrix, Illumina [8600000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cognitive impairment test score","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,2.768712,"[NR] unit decrease","Illumina [575353]","N"]
[51,"rs2179372",20,39811275,"rs4297946","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","PLCG1, ZHX3",null,null,"ENSG00000124181, ENSG00000174306",null,null,"rs4297946-G","rs4297946",0,4297946,"3_prime_UTR_variant",0,0.543,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,0.723,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(Hispanic)",0.11,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,28803291,"rs9257248","2018-07-19",29662059,"Howard DM","2018-04-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29662059","Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.","Depression (broad)","113,769 British ancestry cases, 208,811 British ancestry controls","NA","6p22.1","NR","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,51510,2355,"rs9257248-T","rs9257248",0,9257248,"intergenic_variant",1,0.114,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.0123,"[0.0086-0.016] unit decrease","NR [7666894] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.09,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(Indian)",2.59,"[1.83-3.35] unit increase","Illumina [551825]","N"]
[30,"rs174564",11,61549458,"rs174534","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174534-A","rs174534",0,174534,"non_coding_transcript_exon_variant",0,0.6658,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(Cis/trans-18:2, EA)",0.0029,"[0.0021-0.0037] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61621556,"rs174599","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hypothyroidism","approximately 459,000 European ancestry individuals","NA","11q12.2",null,"FADS2",null,null,"ENSG00000134824",null,null,"rs174599-?","rs174599",0,174599,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.115,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(Hispanic)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112273499,"rs11513729","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","12q24.12","NR","ALDH2 - MAPKAPK5-AS1","ENSG00000111275","ENSG00000234608",null,18166,4069,"rs11513729-C","rs11513729",0,11513729,"intergenic_variant",1,0.588045,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.015227,"[0.011-0.02] unit decrease","Affymetrix [11535925] (imputed)","N"]
[47,"rs8111874",19,49206172,"rs516246","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Crohn's disease","12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls","NA","19q13.33","IZUMO1, NTN5, FUT2, MAMSTR, RASIP1","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-?","rs516246",0,516246,"intron_variant",0,null,{"v":4e-11,"d":"4.00E-11"},10.397940008672,{"$nulls":3},"Illumina [9560910] (imputed)","N"]
[15,"rs6908402",6,26267755,"rs7773004","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist circumference adjusted for BMI (adjusted for smoking behaviour)","97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","6p22.2","HIST1H3G, HIST1H2BH","HIST1H2BH - HIST1H3G","ENSG00000275713","ENSG00000273983",null,13817,1878,"rs7773004-A","rs7773004",0,7773004,"intergenic_variant",1,0.4885,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.0225,"[0.016-0.029] unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47441472,"rs3781627","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Depressive symptoms","1,067,913 European ancestry individuals","228,033 European ancestry individuals","11p11.2","NR","PSMC3",null,null,"ENSG00000165916",null,null,"rs3781627-A","rs3781627",0,3781627,"intron_variant",0,0.694086755463326,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.0066751544,"[0.0047-0.0087] unit increase","NR [NR]","N"]
[30,"rs174564",11,61547237,"rs108499","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs108499-T","rs108499",0,108499,"intron_variant",0,0.3345,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(Cis/trans-18:2, EA)",0.0029,"[0.0021-0.0037] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[38,"rs193695",16,56985139,"rs9989419","2014-03-22",24023261,"Keller M","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023261","THOC5: a novel gene involved in HDL-cholesterol metabolism.","Lipid traits","839 European ancestry individuals","up to 5,248 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.42,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(HDL-C)",6.57,"unit decrease","Affymetrix [390619]","N"]
[46,"rs157592",19,45422160,"rs12721051","2017-03-27",27798624,"Eppinga RN","2016-10-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27798624","Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality.","Resting heart rate","127,919 European ancestry individuals, 2,478 Asian ancestry individuals, 1,734 Black individuals, 684 Mixed ancestry individuals, 1,436 individuals","130,795 European ancestry individuals","19q13.32","APOE, APOC1, PVRL2","APOC1",null,null,"ENSG00000130208",null,null,"rs12721051-G","rs12721051",0,12721051,"3_prime_UTR_variant",0,0.18,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.2874,"[0.2-0.37] unit decrease","Affymetrix [19941912] (imputed)","N"]
[49,"rs2378390",20,34152782,"rs2277862","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","20q11.22","ERGIC3","FER1L4",null,null,"ENSG00000088340",null,null,"rs2277862-T","rs2277862",0,2277862,"non_coding_transcript_exon_variant",0,0.15,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.035,"[NR] unit decrease","NR [NR] (imputed)","N"]
[13,"rs4704210",5,74879890,"rs5744680","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","POLK",null,null,"ENSG00000122008",null,null,"rs5744680-?","rs5744680",0,5744680,"intron_variant",0,"NR",{"v":6E-11,"d":"6.00E-11"},10.2218487496163,{"$nulls":3},"Affymetrix [NR]","N"]
[30,"rs174564",11,61571382,"rs174549","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174549-A","rs174549",0,174549,"5_prime_UTR_variant",0,0.309,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,null,0.02525497,"[0.018-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,0.945,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(EA)",0.072,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-04-21",27899376,"Nakayama A","2016-11-29","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/27899376","GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.","Gout","945 Japanese ancestry cases, 1,213 Japanese ancestry controls","1,396 Japanese ancestry cases, 1,268 Japanese ancestry controls, 1,319 European ancestry cases, 514 European ancestry controls, 971 Polynesian ancestry cases, 565 Polynesian ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.535,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(Japanese)",1.31,"[1.21-1.42]","Illumina [570442]","N"]
[28,"rs10793624",10,46202429,"rs35267807","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","10q11.22",null,"FAM21FP",null,null,"ENSG00000237840",null,null,"rs35267807-?","rs35267807",0,35267807,"intron_variant",0,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2013-03-19",23222517,"van der Harst P","2012-12-05","Nature","www.ncbi.nlm.nih.gov/pubmed/23222517","Seventy-five genetic loci influencing the human red blood cell.","Red blood cell traits","62,553 European ancestry individuals, 9,308 South Asian ancestry individuals","63,506 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(Hgb)",0.034,"[0.022-0.046] unit increase","Affymetrix, Illumina, Perlegen [2711806] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2015-04-24",21239051,"Reilly MP","2011-01-14","Lancet","www.ncbi.nlm.nih.gov/pubmed/21239051","Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.","Coronary artery disease","1,808 European ancestry cases, 915 European ancestry controls","10,585 European ancestry cases, 6,468 European ancestry controls","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.79,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,1.33,"[1.22-1.44]","Affymetrix, Illumina [> 2400000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61609750,"rs174583","2015-04-16",24952745,"Arking DE","2014-06-22","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24952745","Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.","QT interval","Up to 70,389 European ancestry individuals, up to 672 Orcadian individuals","Up to 33,316 European ancestry individuals","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-T","rs174583",0,174583,"intron_variant",0,0.344,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.57,"[0.39-0.75] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs395908",19,45376284,"rs519113","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","19q13.32","APOE, PVRL2, TOMM40","NECTIN2",null,null,"ENSG00000130202",null,null,"rs519113-C","rs519113",0,519113,"intron_variant",0,0.15,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.0179,"[0.012-0.023] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[18,"rs10455872",6,161005610,"rs55730499","2017-11-27",29030599,"Joshi PK","2017-10-13","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29030599","Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.","Parental lifespan","up to 586,626 European ancestry individuals, up to 19,433 African ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.083,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,"(EA)",0.7,"years decrease","Affymetrix, Illumina [at least 13643373] (imputed)","N"]
[21,"rs2409784",8,11433909,"rs2898290","2018-09-14",27618452,"Ehret GB","2016-09-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618452","The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.","Systolic blood pressure","up to 201,529 European ancestry individuals","up to 140,886 European ancestry individuals","8p23.1","BLK, GATA4","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,0.491,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,null,0.377,"[0.26-0.49] mm Hg increase","Affymetrix, Illumina, Perlegen [128272]","N"]
[46,"rs157581",19,45390333,"rs283815","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","PVRL2","NECTIN2, AC011481.2",null,null,"ENSG00000130202, ENSG00000267114",null,null,"rs283815-G","rs283815",0,283815,"intron_variant",0,0.23,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,null,0.15,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.73,{"v":1E-10,"d":"1.00E-10"},10,"(HDL)",0.11,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-10-16",29743933,"Wu B","2018-03-18","Comput Math Methods Med","www.ncbi.nlm.nih.gov/pubmed/29743933","Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits.","Glycemic traits (multi-trait analysis)","5,947 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,{"$nulls":3},"NR [~ 2500000] (imputed)","N"]
[18,"rs139399782",6,161153527,"rs4252134","2017-04-21",28041642,"Carmona FD","2016-12-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28041642","A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis.","Giant cell arteritis","2,134 European ancestry cases, 9,125 European ancestry controls","NA","6q26","PLG","PLG",null,null,"ENSG00000122194",null,null,"rs4252134-?","rs4252134",0,4252134,"intron_variant",0,0.28,{"v":1E-10,"d":"1.00E-10"},10,null,1.28,"[1.19-1.39]","Illumina [1844133] (imputed)","N"]
[22,"rs11986942",8,19819439,"rs326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs326-A","rs326",0,326,"intron_variant",0,0.802,{"v":1E-10,"d":"1.00E-10"},10,"(East Asian)",0.108,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs4360309",8,126523523,"rs4360309","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Basophil percentage of white cells","171,996 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-T","rs4360309",0,4360309,"intron_variant",0,0.4888,{"v":1E-10,"d":"1.00E-10"},10,null,0.02297412,"[0.016-0.03] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs2000571",11,116581641,"rs2367970","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,52673,37245,"rs2367970-G","rs2367970",0,2367970,"intergenic_variant",1,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.033,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112072424,"rs11065987","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-A","rs11065987",0,11065987,"intergenic_variant",1,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs247617",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2013-06-06",23419831,"Ramanan VK","2013-02-19","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/23419831","APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.","Alzheimer's disease biomarkers","555 European ancestry individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.28,{"v":1E-10,"d":"1.00E-10"},10,"(Cortical Ab)",null,null,"Illumina [6108668] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-08-22",29860282,"Scelsi MA","2018-05-30","Brain","www.ncbi.nlm.nih.gov/pubmed/29860282","Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.","Hippocampal volume","926 European ancestry individuals","NA","19q13.32","APOE4","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,null,{"v":1E-10,"d":"1.00E-10"},10,"(uncorrected for APOE4 status)",null,null,"Illumina [5137218] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs61539677",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,0.716,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1461729",8,9178268,"rs6984305","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alkaline phosphatase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6984305-A","rs6984305",0,6984305,"intron_variant",0,0.11,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,2.7,"[1.10-4.40] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin (BMI interaction)","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0937,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.001989,"[0.0001-0.00388] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[22,"rs287",8,19852518,"rs17489282","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,27748,84107,"rs17489282-C","rs17489282",0,17489282,"intergenic_variant",1,0.804,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(East Asian)",0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Hemoglobin levels","up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.","16,389 European and African American individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(Asian)",0.1033,"[0.072-0.135] grams/deciliter decrease","Affymetrix, Illumina [2500000] (imputed)","N"]
[30,"rs174564",11,61571382,"rs174549","2015-07-27",25500335,"Tintle NL","2014-12-02","Prostaglandins Leukot Essent Fatty Acids","www.ncbi.nlm.nih.gov/pubmed/25500335","A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study.","Red blood cell fatty acid levels","2,633 individuals","NA","11q12.2","FADS1, C11orf9, C11orf10, FEN1, FADS2","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174549-?","rs174549",0,174549,"5_prime_UTR_variant",0,0.29,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(GLA)",0.124,"[NR] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.649,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0203,"[0.014-0.027] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[31,"rs117709132",11,116706047,"rs12721025","2014-03-21",23989729,"Feenstra B","2013-08-21","JAMA","www.ncbi.nlm.nih.gov/pubmed/23989729","Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.","Infantile hypertrophic pyloric stenosis","1,001 European ancestry cases, 2,371 European ancestry controls","925 European ancestry cases, 1,621 European ancestry controls, 738 cases, 697 controls","11q23.3","APOA1","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,2259,420,"rs12721025-A","rs12721025",0,12721025,"regulatory_region_variant",1,0.0569,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.59,"[1.38-1.83]","Illumina [9737928] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2016-10-14",26390057,"Kato N","2015-09-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26390057","Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.","Diastolic blood pressure","31,516 East Asian ancestry individuals,  35,352 European ancestry individuals, 33,126 South Asian ancestry individuals","87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.4615,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.5387,"[0.37-0.71] mmHg increase","Affymetrix, Illumina, Perlegen [~ 2100000] (imputed)","N"]
[34,"rs11065358",12,121416650,"rs1169288","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","12q24.31","HNF1A","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-C","rs1169288",0,1169288,"missense_variant",0,0.323,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.04,"[1.02-1.06]","Affymetrix, Illumina [247470]","N"]
[34,"rs7970695",12,121442670,"rs1169313","2008-12-01",18940312,"Yuan X","2008-10-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18940312","Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.","Liver enzyme levels","7,751 European ancestry individuals","1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals","12q24.31","C12orf43, C12orf27, HNF1A","C12orf43",null,null,"ENSG00000157895",null,null,"rs1169313-C","rs1169313",0,1169313,"intron_variant",0,0.38,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(GGT)",0.01,"[0.003-0.007] U/L decrease","Affymetrix, Illumina [up to 496032]","N"]
[38,"rs247617",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.683,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2014-03-26",24046328,"Bradley DT","2013-09-17","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24046328","A variant in LDLR is associated with abdominal aortic aneurysm.","Abdominal aortic aneurysm","1,755 European ancestry cases, 5,314 European ancestry controls","1,658 European ancestry cases, 28,962 European ancestry controls, 1,725 cases, 3,791 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,0.901,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.32,"[1.20-1.43]","Illumina [503892]","N"]
[46,"rs157581",19,45396219,"rs157582","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","TOMM40",{"$nulls":5},"rs157582-T","rs157582",0,157582,"intron_variant",0,0.19,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(Asian initial, BMI unadjusted)",0.108,"[0.075-0.141] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index x sex x age interaction (4df test)","up to 51,625 European ancestry men aged <50, up to 60,654 European ancestry women aged <50, up to 90,988 European ancestry men aged >50, up to 106,622 European ancestry women aged >50","NA","19q13.32","APOC1, ZNF229, IGSF23, BCL3, PVRL2, CLPTM1, GEMIN7, EXOC3L2, KLC3, ZNF180, PVR, CBLC, TOMM40, RELB, PPP1R37, MARK4, ERCC1, CEACAM20, MIR4531, BCAM, APOE, CLASRP, BLOC1S3, CKM, CEACAM22P","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.82,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,{"$nulls":3},"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(VLDL.medium, fasting)",1.32,"[NR] unit decrease","Illumina [335603]","N"]
[9,"rs1260326",2,27748904,"rs1313566","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Prothrombin time","58,110 Japanese ancestry individuals","NA","2p23.3","GCKR, C2orf16","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2353,11349,"rs1313566-?","rs1313566",0,1313566,"intergenic_variant",1,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.03744,"[0.026-0.049] unit increase novel","Illumina [6108953] (imputed)","N"]
[21,"rs1692821",8,11705870,"rs1736089","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1736089-G","rs1736089",0,1736089,"non_coding_transcript_exon_variant",0,0.748125,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(COLEC12)",0.17846595,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[25,"rs535772",9,15289578,"rs471364","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","9p22.3","TTC39B","TTC39B",null,null,"ENSG00000155158",null,null,"rs471364-C","rs471364",0,471364,"intron_variant",0,0.12,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.08,"[0.02-0.14] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Oleic acid (18:1n-9) levels","3,521 Chinese ancestry individuals, European ancestry individuals (see Wu et al 2013)","NA","11q12.2","FADS1, FADS2","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-C","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.419,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(Chinese)",0.204,"[0.14-0.27] unit increase","Affymetrix, Illumina [2200000] (imputed)","N"]
[31,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112072424,"rs11065987","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-A","rs11065987",0,11065987,"intergenic_variant",1,0.564,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs7970695",12,121435587,"rs2259816","2012-11-02",22939635,"Reiner AP","2012-08-28","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/22939635","Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.","C-reactive protein","8,280 African American female individuals, 3,548 Hispanic female individuals","3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals","12q24.31","OASL, C12orf43, HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs2259816-T","rs2259816",0,2259816,"synonymous_variant",0,0.379,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(HA women)",0.141,"[0.092-0.190] unit increase","Affymetrix [up to 2203609] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,null,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,3.34,"[2.03-4.65] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs641990",6,160776017,"rs543159","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","6q25.3","SLC22A3","SLC22A3",null,null,"ENSG00000146477",null,null,"rs543159-A","rs543159",0,543159,"intron_variant",0,0.482,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.035,"[0.023-0.047] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.161,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(Hispanic)",0.104,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs1800978",9,107653426,"rs12686004","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-?","rs12686004",0,12686004,"intron_variant",0,null,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[31,"rs508487",11,117045335,"rs7925256","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","11q23.3",null,"PAFAH1B2",null,null,"ENSG00000168092",null,null,"rs7925256-T","rs7925256",0,7925256,"intron_variant",0,0.0907,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(conditional-joint)",0.0154,"[0.011-0.02] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[33,"rs35350651",12,112007756,"rs653178","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-?","rs653178",0,653178,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.0507,"[0.035-0.067] unit decrease","Illumina [at least 560000] (imputed)","N"]
[38,"rs118146573",16,57000938,"rs118146573","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","Cholesterol, total","3,701 Mexican ancestry individuals","5,114 Mexican ancestry individuals, 903 Mexican ancestry individuals from 73 dyslipidemic families","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-A","rs118146573",0,118146573,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.2,"[NR] unit decrease","Illumina [1661241] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index","up to 309,889 European ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.847998234602839,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.025690204,"unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA, Repulsive guidance molecule A)",0.3237,"[0.22-0.42] unit decrease","Affymetrix [509946]","N"]
[24,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,0.485,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA)",0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.65,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(Asian initial, BMI unadjusted)",0.059,"[0.041-0.077] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[34,"rs7970695",12,121438844,"rs735396","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.4,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(FUC-A)",0.16801201,"[0.12-0.22] (zscore) decrease","Illumina [NR]","N"]
[49,"rs2378390",20,34143278,"rs3790136","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q11.22","NR","ERGIC3",null,null,"ENSG00000125991",null,null,"rs3790136-A","rs3790136",0,3790136,"intron_variant",0,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs56912706",5,75034387,"rs7715806","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,21081,14008,"rs7715806-C","rs7715806",0,7715806,"intergenic_variant",1,0.6006,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.023,"[0.016-0.03] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[18,"rs10455872",6,161005610,"rs55730499","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (mother's attained age)","412,937 British ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-C","rs55730499",0,55730499,"intron_variant",0,"NR",{"v":6E-10,"d":"6.00E-10"},9.22184874961635,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,0.28,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(Ht)",0.081,"[0.056-0.106] unit decrease","Illumina [561583]","N"]
[30,"rs174564",11,61588305,"rs174564","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Pulse pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","11q12.2","FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174564-G","rs174564",0,174564,"intron_variant",0,0.6728,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.1696,"[0.12-0.22] mmHg increase","Affymetrix [NR] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Smoking cessation (MTAG)","up to 820,192 European ancestry individuals","NA","19q13.2","NR","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-C","rs56113850",0,56113850,"intron_variant",0,0.567,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.00974331,"[0.0067-0.0128] unit decrease","NR [9732723] (imputed)","N"]
[46,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,0.645,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(East Asian)",0.106,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs34121855",7,73042085,"rs62466318","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3212,40070,"rs62466318-T","rs62466318",0,62466318,"intergenic_variant",1,0.204,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,0.01704703,"[0.012-0.022] unit increase","Affymetrix [11514936] (imputed)","N"]
[30,"rs174564",11,61543499,"rs174528","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Vaccenic acid (18:1n-7) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","11q12.2","FADS1, FADS2","MYRF, TMEM258",null,null,"ENSG00000124920, ENSG00000134825",null,null,"rs174528-C","rs174528",0,174528,"intron_variant",0,"NR",{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,0.018,"[0.012-0.024] unit increase","Affymetrix, Illumina [2200000] (imputed)","N"]
[46,"rs2238681",19,45401666,"rs8106922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs8106922-A","rs8106922",0,8106922,"intron_variant",0,0.674,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(East Asian)",0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(SUMF1)",0.31651577,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[13,"rs4704210",5,74934009,"rs34341","2018-07-09",29691431,"Tikkanen E","2018-04-24","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29691431","Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.","Hand grip strength","334,825 British ancestry individuals","NA","5q13.3","ANKDD1B","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs34341-A","rs34341",0,34341,"intron_variant",0,0.4242,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,2E-3,"[0.0014-0.0026] unit increase","Affymetrix [15275733] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[31,"rs6589563",11,116590787,"rs6589563","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil counts","172,275 European ancestry individuals","NA","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,61819,28099,"rs6589563-A","rs6589563",0,6589563,"intergenic_variant",1,0.0786,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,0.0410643,"[0.028-0.054] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[31,"rs35120633",11,116603724,"rs12272004","2009-02-28",19185284,"Ferrucci L","2009-01-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/19185284","Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.","Carotenoid and tocopherol levels","1,191 European ancestry individuals","2,540 European ancestry individuals, 211 individuals","11q23.3","APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,74756,15162,"rs12272004-A","rs12272004",0,12272004,"TF_binding_site_variant",1,0.07,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,"(alpha-tocopherol)",0.07,"[0.049-0.095] umol/L increase","Illumina [~ 500451]","N"]
[47,"rs8111874",19,49206172,"rs516246","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-T","rs516246",0,516246,"intron_variant",0,0.47,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,2.3,"[1.80-2.90] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[7,"rs907866",2,20369701,"rs870527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC098828.1 - RN7SL140P","ENSG00000213729","ENSG00000266059",null,13883,5406,"rs870527-T","rs870527",0,870527,"TF_binding_site_variant",1,"NR",{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,"NR",{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,6.132,"z-score decrease","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[30,"rs174564",11,61619829,"rs174594","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174594-A","rs174594",0,174594,"intron_variant",0,0.6242,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,0.02313224,"[0.016-0.031] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,112072424,"rs11065987","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-A","rs11065987",0,11065987,"intergenic_variant",1,0.564,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-04-30",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Total cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.27,{"v":1e-09,"d":"1.00E-09"},9,"(Indian)",5.42,"[3.68-7.16] unit decrease","Illumina [551825]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Isoleucine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-09,"d":"1.00E-09"},9,null,0.06,"[0.036-0.084] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2009-06-22",19503597,"Kolz M","2009-06-05","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19503597","Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.","Uric acid levels","12,328 European ancestry males, 15,813 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.42,{"v":1e-09,"d":"1.00E-09"},9,null,0.05,"[0.035-0.068] mg/dl increase","Affymetrix, Illumina [2493963] (imputed)","N"]
[16,"rs1233489",6,29044701,"rs3131085","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","6p22.1","GABBR1, OR12D3, XXbac-BPG308K3.5, TRIM27, AL662791.1, OR2AD1P, OR2P1P, OR2B3, XXbac-BCX196D17.5, OR2N1P, OR2H4P, OR2B4P, XXbac-BPG308K3.6, RPL13P, ZNF90P2, HCG14, RNU6-930P, LINC01556, KRT18P1, RN7SL471P, HCG15, HCG16, ZNF311, XXbac-BPG258E24.10, OR2W1, SAR1P1, OR2J3, OR2J4P, OR2J2, AL645937.1, XXbac-BPG308J9.3, OR2U2P, OR14J1, OR5V1, OR10C1, OR11A1, XXbac-BPG13B8.11, OR2H1, UBDP1, MAS1LP1, MAS1L, RPS17P1, XXbac-BPG13B8.10, OR2I1P, UBD","SAR1AP1, SAR1AP1, SAR1AP1, SAR1AP1, SAR1AP1, SAR1AP1, SAR1AP1",null,null,"ENSG00000226795, ENSG00000238070, ENSG00000226657, ENSG00000227529, ENSG00000229179, ENSG00000228364, ENSG00000231592",null,null,"rs3131085-A","rs3131085",0,3131085,"non_coding_transcript_exon_variant",0,0.07580321,{"v":1e-09,"d":"1.00E-09"},9,"(EA, MHC class I polypeptide-related sequence A)",0.5111,"[0.35-0.67] unit increase","Affymetrix [509946]","N"]
[19,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-A","rs2954022",0,2954022,"intron_variant",0,0.48,{"v":1e-09,"d":"1.00E-09"},9,null,0.036,"[0.024-0.048] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[26,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47761471,"rs11602339","2017-10-27",28892062,"Akiyama M","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892062","Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.","Body mass index","up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men","up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls","11p11.2","FNBP4","FNBP4",null,null,"ENSG00000109920",null,null,"rs11602339-T","rs11602339",0,11602339,"intron_variant",0,0.313,{"v":1e-09,"d":"1.00E-09"},9,"(Japanese)",0.023,"[0.015-0.031] kg/m2 increase","Illumina [6108953] (imputed)","N"]
[30,"rs174564",11,61569830,"rs174546","2019-02-26",30679814,"van Setten J","2019-01-24","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30679814","Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.","QT interval","2,332 Erasmus Rucphen Family (founder/genetic isolate) individuals, 24,462 European ancestry individuals","391 Carlantino (founder/genetic isolate) individuals, 981 Friuli Venezia Giulia (founder/genetic isolate) individuals, 31,225 European ancestry individuals, 2,048 African American individuals","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174546-T","rs174546",0,174546,"3_prime_UTR_variant",0,0.334,{"v":1e-09,"d":"1.00E-09"},9,null,1.238,"[0.84-1.64] unit decrease","Affymetrix, Illumina [at least 19000000] (imputed)","N"]
[31,"rs734104",11,116684028,"rs7396835","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","11q23.3","intergenic","AP006216.2",null,null,"ENSG00000236267",null,null,"rs7396835-T","rs7396835",0,7396835,"non_coding_transcript_exon_variant",0,0.32,{"v":1e-09,"d":"1.00E-09"},9,"(TG)",0.23,"[NR] mg/dL increase","Affymetrix [408775]","N"]
[31,"rs117709132",11,116706047,"rs12721025","2018-12-11",30281099,"Fadista J","2018-10-02","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30281099","Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis.","Infantile hypertrophic pyloric stenosis","1,395 Danish ancestry cases, 4,438 Danish ancestry controls","1,794 European ancestry cases, 633 Hispanic ancestry cases, 1,875 European ancestry controls, 633 Hispanic ancestry controls","11q23.3","NR","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,2259,420,"rs12721025-A","rs12721025",0,12721025,"regulatory_region_variant",1,0.0606306977387014,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",1.45,"[1.33-1.57]","Illumina [6576307] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2016-07-24",26192919,"Liu JZ","2015-07-20","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26192919","Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.","Inflammatory bowel disease","12,882 European ancestry cases, 21,770 European ancestry controls","25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(EA)",null,null,"Affymetrix, Illumina [~ 9000000] (imputed)","N"]
[37,"rs261341",15,58724792,"rs8034802","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","HDL cholesterol","7,813 African American individuals","4,323 African American and Afro-Caribbean individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs8034802-A","rs8034802",0,8034802,"intron_variant",0,0.362,{"v":1e-09,"d":"1.00E-09"},9,null,0.104,"[0.071-0.137] unit increase","Affymetrix [~ 2740000] (imputed)","N"]
[42,"rs4939883",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(HDL.large, fasting)",0.353,"[NR] unit decrease","Illumina [335603]","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.9,{"v":1e-09,"d":"1.00E-09"},9,"(Hispanic)",0.153,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2015-04-02",25006744,"Castaldi PJ","2014-07-09","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/25006744","Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.","Local histogram emphysema pattern","3,732 European ancestry smoker individuals, 2,724 European ancestry chronic obstructive pulmonary disease smoker cases, 2,372 African American smoker individuals, 786 African American chronic obstructive pulmonary disease smoker cases","NA","19q13.2","CYP2A6","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-T","rs56113850",0,56113850,"intron_variant",0,0.4,{"v":1e-09,"d":"1.00E-09"},9,"(Moderate Centrilobular)",0.02,"[0.012-0.028] unit decrease","Illumina [6942916] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63118196,"rs10889353","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.14,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.126,"[0.085-0.167] unit decrease","Illumina [561583]","N"]
[8,"rs6544366",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(TG.assay, fasting)",0.047,"[NR] unit decrease","Illumina [335603]","N"]
[9,"rs3817588",2,27743154,"rs780092","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-?","rs780092",0,780092,"intron_variant",0,null,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[18,"rs12208357",6,160543148,"rs12208357","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs12208357-C","rs12208357",0,12208357,"missense_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs7005363",8,10243101,"rs6601450","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of granulocytes","170,536 European ancestry individuals","NA","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs6601450-T","rs6601450",0,6601450,"intron_variant",0,0.4528,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02168981,"[0.015-0.029] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[21,"rs2409784",8,11435516,"rs10108511","2017-03-13",27527254,"Gharahkhani P","2016-08-12","Lancet Oncol","www.ncbi.nlm.nih.gov/pubmed/27527254","Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.","Barrett's esophagus  or Esophageal adenocarcinoma","6,167 European ancestry Barrett's oesophagus cases, 4,112 European ancestry esophageal adenocarcinoma cases, 17,159 European ancestry controls","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs10108511-T","rs10108511",0,10108511,"intron_variant",0,null,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1.12,"[1.08-1.16]","Illumina [11951684] (imputed)","N"]
[24,"rs2954021",8,126477978,"rs2001945","2019-03-19",30604766,"Morris AP","2019-01-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30604766","Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.","Estimated glomerular filtration rate","134,070 European ancestry individuals, 143,658 East Asian ancestry individuals, 26,344 Hispanic or Latino ancestry individuals, 8,224 African American individuals","NA","8q24.13","TRIB1","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27331,1203,"rs2001945-C","rs2001945",0,2001945,"intergenic_variant",1,0.546,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.264,"[0.086-0.442] ml/min/1.73m2 decrease","Affymetrix, Illumina [at least 5248638] (imputed)","N"]
[27,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.65,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(Asian initial, BMI unadjusted)",0.057,"[0.039-0.075] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[29,"rs12790666",11,47441513,"rs10838708","2019-03-25",30804566,"Lane JM","2019-02-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30804566","Biological and clinical insights from genetics of insomnia symptoms.","Insomnia symptoms (never/rarely vs. usually)","129,270 European ancestry cases, 108,357 European ancestry controls","17,140 European ancestry cases, 61,850 European ancestry controls","11p11.2","PSMC3","PSMC3",null,null,"ENSG00000165916",null,null,"rs10838708-G","rs10838708",0,10838708,"intron_variant",0,0.541245,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1.02,"[1.01-1.03]","Affymetrix [14661600] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","11q12.2","FADS1","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.6571,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1E-3,"[-0.00036-0.00236] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[31,"rs688456",11,116728630,"rs12225230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs12225230-G","rs12225230",0,12225230,"missense_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.03,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Diastolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.4816,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.1536,"[0.1-0.2] mmHg increase","Affymetrix [NR] (imputed)","N"]
[33,"rs35350651",12,112200150,"rs2013002","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ALDH2","AC002996.1",null,null,"ENSG00000257767",null,null,"rs2013002-T","rs2013002",0,2013002,"intron_variant",0,0.44,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.896,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(Hispanic)",0.15,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157595",19,45414451,"rs439401","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","19q13.32","APOE, TOMM40","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-G","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.68,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.09,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[2,"rs548179580",1,25747230,"rs586178","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p36.11","LDLRAP1","RHCE",null,null,"ENSG00000188672",null,null,"rs586178-C","rs586178",0,586178,"missense_variant",0,0.5,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.037,"[0.025-0.049] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[2,"rs548179580",1,25775733,"rs12027135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","MACO1",null,null,"ENSG00000204178",null,null,"rs12027135-A","rs12027135",0,12027135,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.3929,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.0189,"[0.013-0.025] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[12,"rs6818397",4,3434885,"rs6818397","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","4p16.3","LRPAP1","RGS12",null,null,"ENSG00000159788",null,null,"rs6818397-T","rs6818397",0,6818397,"intron_variant",0,0.413,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Trans-ethnic initial)",0.0224,"[0.015-0.03] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[19,"rs34121855",7,73026378,"rs17145750","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-T","rs17145750",0,17145750,"intron_variant",0,0.1611,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.02935932,"[0.02-0.039] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.874,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs11250098",8,10815571,"rs10109025","2017-05-11",27182965,"Pickrell JK","2016-05-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27182965","Detection and interpretation of shared genetic influences on 42 human traits.","Joint mobility (Beighton score)","64,143 European ancestry individuals","NA","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs10109025-?","rs10109025",0,10109025,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.068,"[0.090-0.045] unit decrease","Illumina [12039492] (imputed)","N"]
[22,"rs7816447",8,19919655,"rs4128744","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,94885,16970,"rs4128744-A","rs4128744",0,4128744,"regulatory_region_variant",1,0.11,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Indian)",2.21,"[1.48-2.94] unit increase","Illumina [551825]","N"]
[27,"rs115478735",9,136154867,"rs495828","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Hematocrit","up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.","16,389 European and African American individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Asian)",0.2708,"[0.18-0.36] percentage decrease","NR [2500000] (imputed)","N"]
[30,"rs198459",11,61471678,"rs198457","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Well-being spectrum (multivariate analysis)","2,083,151 European ancestry individuals","287,239 European ancestry individuals","11q12.2","NR","DAGLA",null,null,"ENSG00000134780",null,null,"rs198457-T","rs198457",0,198457,"intron_variant",0,0.18779776750139,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.007003807,"[0.0047-0.0093] unit decrease","NR [NR]","N"]
[31,"rs35120633",11,116626258,"rs11825181","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Triglycerides-Blood Pressure (TG-BP)","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs11825181-A","rs11825181",0,11825181,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.32,"[0.22-0.42] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[33,"rs35350651",12,112059557,"rs11065979","2018-05-14",22961000,"Liu JZ","2012-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22961000","Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.","Primary biliary cirrhosis","2,861 British and Irish ancestry cases, 8,514 British and Irish ancestry controls","NA","12q24.12","ATXN2, BRAP, SH2B3","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-A","rs11065979",0,11065979,"intergenic_variant",1,0.44,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,1.2,"[1.13-1.27]","Illumina [237619] (imputed)","N"]
[37,"rs6494005",15,58724524,"rs6494005","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs6494005-A","rs6494005",0,6494005,"non_coding_transcript_exon_variant",0,0.75,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(BMI unadjusted)",0.024,"[0.016-0.032] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.4,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(HDL-C)",0.04,"[0.020-0.060] unit increase","Affymetrix [~ 3700000] (imputed)","N"]
[46,"rs11881756",19,45220896,"rs11881756","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","AC243964.2",null,null,"ENSG00000266903",null,null,"rs11881756-?","rs11881756",0,11881756,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.1415,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.0301972,"[0.02-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62931632,"rs1167998","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1167998-?","rs1167998",0,1167998,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(VLDL.small, fasting)",1.505,"[NR] unit decrease","Illumina [335603]","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.656,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(Hispanic)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2015-04-24",25187374,"Hwang JY","2014-09-03","Diabetes","www.ncbi.nlm.nih.gov/pubmed/25187374","Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.","Fasting plasma glucose","24,740 East Asian ancestry individuals","21,345 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.052,"[0.034-0.070] unit increase","Affymetrix, Illumina [up to 2315813] (imputed)","N"]
[18,"rs143843429",6,161383079,"rs143843429","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","6q26","NR","AL139393.1",null,null,"ENSG00000231863",null,null,"rs143843429-A","rs143843429",0,143843429,"intron_variant",0,0.983804,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.0549336,"[0.037-0.073] unit decrease","Affymetrix [11535925] (imputed)","N"]
[22,"rs7816447",8,19905904,"rs78299715","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","8p21.3",null,"LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,81134,30721,"rs78299715-?","rs78299715",0,78299715,"intergenic_variant",1,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs73664373",9,107647019,"rs11789603","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs11789603-C","rs11789603",0,11789603,"intron_variant",0,0.893,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(EA)",0.044,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[28,"rs148063610",10,46018831,"rs11239549","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q11.22","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239549-A","rs11239549",0,11239549,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61619829,"rs174594","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Hemoglobin A1c levels","42,790 Japanese ancestry individuals","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174594-?","rs174594",0,174594,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.04208,"[0.028-0.056] unit increase novel","Illumina [6108953] (imputed)","N"]
[34,"rs7970695",12,121438844,"rs735396","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.39,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(DG11)",0.15703972,"[0.1-0.21] (zscore) increase","Illumina [NR]","N"]
[42,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.075,"[0.05-0.1] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[44,"rs58542926",19,19610596,"rs3794991","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19p13.11","GATAD2A, CILP2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs3794991-T","rs3794991",0,3794991,"intron_variant",0,0.0775,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.077,"[0.052-0.102] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[51,"rs2179372",20,39713869,"rs2223745","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","20q12",null,"TOP1",null,null,"ENSG00000198900",null,null,"rs2223745-?","rs2223745",0,2223745,"intron_variant",0,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[13,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,0.466,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(East Asian)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs56912706",5,75034387,"rs7715806","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,21081,14008,"rs7715806-?","rs7715806",0,7715806,"intergenic_variant",1,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,{"$nulls":3},"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.899,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(Hispanic)",0.137,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.0384,"[0.025-0.051] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61600342,"rs174574","2018-09-20",28869591,"Kemp JP","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869591","Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.","Heel bone mineral density","76,067 European ancestry women, 66,420 European ancestry men","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174574-A","rs174574",0,174574,"intron_variant",0,0.353366,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.0202955,"[0.013-0.027] unit increase","NR [17166351] (imputed)","N"]
[32,"rs11282820",12,109879292,"rs11608355","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","12q24.11","NR","MYO1H",null,null,"ENSG00000174527",null,null,"rs11608355-C","rs11608355",0,11608355,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.01457,"[0.0097-0.0195] unit increase","Affymetrix [10847151] (imputed)","N"]
[43,"rs576249617",19,11229218,"rs2738452","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs2738452-A","rs2738452",0,2738452,"intron_variant",0,0.83,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(BMI unadjusted)",0.081,"[0.054-0.108] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.66,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(Hispanic)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,29075088,"rs3129178","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","OR2J1 - OR2J3","ENSG00000225441","ENSG00000232178",null,4610,748,"rs3129178-A","rs3129178",0,3129178,"intergenic_variant",1,0.0951,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(EA)",0.0669,"[0.044-0.089] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[16,"rs1233489",6,29356331,"rs9257809","2017-03-13",27527254,"Gharahkhani P","2016-08-12","Lancet Oncol","www.ncbi.nlm.nih.gov/pubmed/27527254","Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.","Barrett's esophagus  or Esophageal adenocarcinoma","6,167 European ancestry Barrett's oesophagus cases, 4,112 European ancestry esophageal adenocarcinoma cases, 17,159 European ancestry controls","NA","6p22.1","MHC","OR5V1, OR5V1, OR5V1, OR5V1, OR5V1",null,null,"ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000112461, ENSG00000243441",null,null,"rs9257809-A","rs9257809",0,9257809,"intron_variant",0,null,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,1.23,"[1.14-1.31]","Illumina [11951684] (imputed)","N"]
[24,"rs2954021",8,126478450,"rs2001846","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27803,731,"rs2001846-?","rs2001846",0,2001846,"intergenic_variant",1,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.03046,"[0.02-0.041] unit decrease novel","Illumina [6108953] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Alanine transaminase levels","134,182 Japanese ancestry individuals","NA","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-?","rs174551",0,174551,"5_prime_UTR_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.02324,"[0.015-0.031] unit decrease","Illumina [6108953] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.015,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2018-10-19",30093612,"O'Mara TA","2018-08-09","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30093612","Identification of nine new susceptibility loci for endometrial cancer.","Endometrial cancer (endometrioid histology)","8,758 European ancestry cases, 46,126 European ancestry controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.515767,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,1.11,"[1.07-1.15]","Affymetrix, Illumina [~ 11700000] (imputed)","N"]
[5,"rs3832016",1,109821511,"rs602633","2017-04-05",27899403,"Jones GT","2016-11-29","Circ Res","www.ncbi.nlm.nih.gov/pubmed/27899403","Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.","Abdominal aortic aneurysm","4,972 European ancestry cases, 99,858 European ancestry controls","2,482 European ancestry cases, 2,750 cases, 2,645 European ancestry controls, 5,263 controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.199,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.14,"[1.09-1.19]","Affymetrix, Illumina [5363770] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.358,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Hispanic)",0.0688,"[NR] unit increase","Affymetrix [NR]","N"]
[22,"rs73600084",8,19848080,"rs17410962","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,23310,88545,"rs17410962-G","rs17410962",0,17410962,"intergenic_variant",1,0.112,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Hispanic)",0.1064,"[NR] unit decrease","Affymetrix [NR]","N"]
[22,"rs7816447",8,19860460,"rs79236614","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","Triglycerides","1,678 Mexican ancestry high triglyceride cases, 1,645 Mexican ancestry low triglyceride controls","2,129 Mexican ancestry high triglyceride cases, 2,985 Mexican ancestry low triglyceride controls, 903 Mexican ancestry individuals from 73 dyslipidemic families","8p21.3","SLC18A1, LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,35690,76165,"rs79236614-?","rs79236614",0,79236614,"intergenic_variant",1,"NR",{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.89,"[1.49-2.38]","Illumina [1661241] (imputed)","N"]
[27,"rs9411377",9,136149098,"rs116552240","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Lactate dehydrogenase levels","126,319 Japanese ancestry individuals","NA","9q34.2","ABO","ABO",null,null,"ENSG00000175164",null,null,"rs116552240-?","rs116552240",1,8176645,"intron_variant",0,"NR",{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.02354,"[0.016-0.032] unit increase novel","Illumina [6108953] (imputed)","N"]
[30,"rs2072114",11,61604782,"rs2524299","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2524299-A","rs2524299",0,2524299,"intron_variant",0,0.8756,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Cis/trans-18:2, EA)",0.0037,"[0.0025-0.0049] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.869,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(AA)",0.217,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2017-12-11",22885922,"Morris AP","2012-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22885922","Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.","Type 2 diabetes","6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls","12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.080536977769365,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.13,"[1.09-1.18]","Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[46,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.911,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(East Asian)",0.174,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs13013484",2,28019175,"rs4666014","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Hematocrit","108,757 Japanese ancestry individuals","NA","2p23.2","RBKS","RBKS, MRPL33",null,null,"ENSG00000171174, ENSG00000243147",null,null,"rs4666014-?","rs4666014",0,4666014,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.02427,"[0.016-0.033] unit increase novel","Illumina [6108953] (imputed)","N"]
[24,"rs2954021",8,126479362,"rs6982502","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum total protein level","113,509 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982502-?","rs6982502",0,6982502,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.02423,"[0.016-0.032] unit decrease novel","Illumina [6108953] (imputed)","N"]
[24,"rs2954038",8,126484526,"rs2954026","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954026-G","rs2954026",0,2954026,"intron_variant",0,"NR",{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.16,"[0.10-0.22] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8775,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(ANGPTL3)",0.21391149,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.49,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(East Asian)",0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2011-09-01",21829377,"Lemaitre RN","2011-07-28","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829377","Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)","8,866 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,"NR",{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,0.02,"[NR] % increase","Affymetrix, Illumina [NR]","N"]
[18,"rs12208357",6,160543148,"rs12208357","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs12208357-C","rs12208357",0,12208357,"missense_variant",0,0.925,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,"(EA)",0.046,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2017-05-11",27182965,"Pickrell JK","2016-05-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27182965","Detection and interpretation of shared genetic influences on 42 human traits.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","9q34.2","ABO, SURF6","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,1.06,"[1.039-1.081]","Illumina [13757430] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cognitive impairment test score","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,null,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,2.722685,"[NR] unit decrease","Illumina [575353]","N"]
[5,"rs3832016",1,109821511,"rs602633","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease","33,398 cases, 75,726 controls","NA","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-?","rs602633",0,602633,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,1.1111,"[1.08-1.15]","Illumina [575000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or ischemic stroke","12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls","NA","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-?","rs599839",0,599839,"regulatory_region_variant",1,null,{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[13,"rs253412",5,75015242,"rs2112347","2013-09-12",23563607,"Berndt SI","2013-04-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23563607","Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.","Obesity","93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls","65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls","5q13.3","C5orf37","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.63,{"v":1E-8,"d":"1.00E-08"},8,"(Overweight)",1.04,"[NR]","Affymetrix, Illumina [~ 2800000] (imputed)","N"]
[15,"rs6908402",6,26267755,"rs7773004","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)","97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","6p22.2","HIST1H3G, HIST1H2BH","HIST1H2BH - HIST1H3G","ENSG00000275713","ENSG00000273983",null,13817,1878,"rs7773004-A","rs7773004",0,7773004,"intergenic_variant",1,0.4885,{"v":1E-8,"d":"1.00E-08"},8,"(men)",null,null,"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[21,"rs11250098",8,10758213,"rs10107145","2017-09-22",28739976,"Wain LV","2017-07-24","Hypertension","www.ncbi.nlm.nih.gov/pubmed/28739976","Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.","Systolic blood pressure","150,134 European ancestry individuals","87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals","8p23.1","intergenic","XKR6",null,null,"ENSG00000171044",null,null,"rs10107145-G","rs10107145",0,10107145,"intron_variant",0,0.528,{"v":1E-8,"d":"1.00E-08"},8,"(EA, initial)",0.406,"[0.26-0.55] unit decrease","Affymetrix, Illumina, Perlegen [7994604] (imputed)","N"]
[21,"rs4841600",8,11689228,"rs2409836","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","FDFT1","FDFT1",null,null,"ENSG00000079459",null,null,"rs2409836-T","rs2409836",0,2409836,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.0099608,"[0.0065-0.0134] unit decrease","Affymetrix [18485882] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Red blood cell count","up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.","16,389 individuals of European and African American ancestry.","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-?","rs495828",0,495828,"regulatory_region_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47606483,"rs11605348","2019-01-21",29970889,"Day FR","2018-07-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29970889","Elucidating the genetic basis of social interaction and isolation.","Loneliness (MTAG)","487,647 European ancestry individuals","NA","11p11.2","MADD, MYBPC3, SPI1, SLC39A13, PSMC3, RAPSN, CELF1, PTPMT1, KBTBD4, NDUFS3, FAM180B, C1QTNF4, MTCH2, AGBL2, FNBP4, NUP160","NDUFS3 - FAM180B","ENSG00000213619","ENSG00000196666",null,369,1762,"rs11605348-G","rs11605348",0,11605348,"intergenic_variant",1,0.649676,{"v":1E-8,"d":"1.00E-08"},8,null,0.012172433,"[0.008-0.0164] unit increase","NR [NR] (imputed)","N"]
[30,"rs198459",11,61471678,"rs198457","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Positive affect","410,603 European ancestry individuals","NA","11q12.2","NR","DAGLA",null,null,"ENSG00000134780",null,null,"rs198457-T","rs198457",0,198457,"intron_variant",0,0.18779776750139,{"v":1E-8,"d":"1.00E-08"},8,null,0.008670836,"[0.0057-0.0117] unit decrease","NR [NR]","N"]
[30,"rs174564",11,61543499,"rs174528","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Vaccenic acid (18:1n-7) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","11q12.2","FADS1, FADS2","MYRF, TMEM258",null,null,"ENSG00000124920, ENSG00000134825",null,null,"rs174528-C","rs174528",0,174528,"intron_variant",0,0.368,{"v":1E-8,"d":"1.00E-08"},8,"(EA)",0.021,"[0.013-0.029] unit increase","Affymetrix, Illumina [2200000] (imputed)","N"]
[31,"rs12721028",11,116780095,"rs75920871","2018-02-27",29292387,"Turley P","2018-01-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29292387","Multi-trait analysis of genome-wide association summary statistics using MTAG.","Subjective well-being","388,538 European ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs75920871-T","rs75920871",0,75920871,"intron_variant",0,0.1468,{"v":1E-8,"d":"1.00E-08"},8,null,0.0183,"[0.012-0.025] unit decrease","Illumina [NR] (imputed)","N"]
[33,"rs35350651",12,111910219,"rs10774625","2017-10-24",28898252,"Wheeler E","2017-09-12","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/28898252","Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.","Glycated hemoglobin levels","88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals","33,238 European ancestry individuals,  2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs10774625-G","rs10774625",0,10774625,"intron_variant",0,0.5056,{"v":1E-8,"d":"1.00E-08"},8,"(European)",0.0088,"[0.0057-0.0119] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[36,"rs6602911",13,114542858,"rs9604573","2017-10-24",28898252,"Wheeler E","2017-09-12","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/28898252","Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.","Glycated hemoglobin levels","88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals","33,238 European ancestry individuals,  2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals","13q34","GAS6","GAS6-AS1, GAS6",null,null,"ENSG00000233695, ENSG00000183087",null,null,"rs9604573-T","rs9604573",0,9604573,"non_coding_transcript_exon_variant",0,0.2738,{"v":1E-8,"d":"1.00E-08"},8,"(European)",0.0101,"[0.0066-0.0136] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[37,"rs261290",15,58680954,"rs2043085","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043085-A","rs2043085",0,2043085,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,"(HDLC-GLUC)",0.17,"[0.11-0.23] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[38,"rs4783961",16,56994894,"rs4783961","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16118,941,"rs4783961-G","rs4783961",0,4783961,"regulatory_region_variant",1,0.44,{"v":1E-8,"d":"1.00E-08"},8,"(Indian)",1.29,"[0.84-1.74] unit decrease","Illumina [551825]","N"]
[43,"rs56048141",19,11317744,"rs56048141","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","19p13.2",null,"DOCK6, AC011472.1",null,null,"ENSG00000130158, ENSG00000267082",null,null,"rs56048141-?","rs56048141",0,56048141,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs157581",19,45396219,"rs157582","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs157582-T","rs157582",0,157582,"intron_variant",0,0.22,{"v":1E-8,"d":"1.00E-08"},8,"(TG)",0.1,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[47,"rs8111874",19,49213284,"rs584768","2019-02-26",30566020,"Fukaya E","2018-12-01","Circulation","www.ncbi.nlm.nih.gov/pubmed/30566020","Clinical and Genetic Determinants of Varicose Veins.","Varicose veins","9,577 British ancestry cases, 327,959 British ancestry controls","NA","19q13.33","NR","FUT2 - MAMSTR","ENSG00000176920","ENSG00000176909",null,4077,2715,"rs584768-A","rs584768",0,584768,"intergenic_variant",1,0.53,{"v":1E-8,"d":"1.00E-08"},8,null,0.084,"[0.055-0.113] unit increase","Affymetrix [10972371] (imputed)","N"]
[2,"rs548179580",1,25758134,"rs11249249","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","1p36.11",null,"MACO1",null,null,"ENSG00000204178",null,null,"rs11249249-?","rs11249249",0,11249249,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[7,"rs907866",2,20367973,"rs11899121","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC098828.1 - RN7SL140P","ENSG00000213729","ENSG00000266059",null,12155,7134,"rs11899121-G","rs11899121",0,11899121,"regulatory_region_variant",1,0.509,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum albumin level","Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.56,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Japanese)",0.027,"[0.017-0.037] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-08-10",29844224,"Loomis SJ","2018-05-29","Diabetes","www.ncbi.nlm.nih.gov/pubmed/29844224","Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results from the Atherosclerosis Risk in Communities Study.","Percent glycated albumin","7,647 European ancestry individuals, 2,104 Black individuals","1,304 European ancestry individuals, 608 Black individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.01,"[0.0061-0.0139] unit decrease","Affymetrix [NR] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.467,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,0.49,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs253412",5,75015242,"rs2112347","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.629,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.024,"[0.016-0.032] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[16,"rs1233489",6,29260431,"rs3117425","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","6p22.1","NR","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3117425-T","rs3117425",0,3117425,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.02019,"[0.013-0.027] unit decrease","Affymetrix [10847151] (imputed)","N"]
[18,"rs641990",6,160791370,"rs3127574","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index (age>50)","up to 90,988 European ancestry men, up to 106,622 European ancestry women","NA","6q25.3","SLC22A3, MAS1, AIRN, IGF2R, SLC22A1, SLC22A2, LPAL2, LPA, PLG, LOC729603","SLC22A3",null,null,"ENSG00000146477",null,null,"rs3127574-C","rs3127574",0,3127574,"intron_variant",0,0.51,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.019,"unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","Triglyceride levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","8p21.3","LPL, RPL30P9","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-A","rs12678919",0,12678919,"intergenic_variant",1,null,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Japanese)",0.23,"[0.15-0.31] unit decrease","Illumina [1294241]","N"]
[26,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2017-09-22",28566273,"Scott RA","2017-05-31","Diabetes","www.ncbi.nlm.nih.gov/pubmed/28566273","An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.","Type 2 diabetes","up to 26,676 European ancestry cases, up to 132,532 European ancestry controls","14,545 European ancestry cases, 38,994 European ancestry controls","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.08,"[1.05-1.10]","Affymetrix, Illumina [at least 11579618] (imputed)","N"]
[30,"rs61897793",11,61595564,"rs968567","2014-08-05",24390342,"Okada Y","2013-12-25","Nature","www.ncbi.nlm.nih.gov/pubmed/24390342","Genetics of rheumatoid arthritis contributes to biology and drug discovery.","Rheumatoid arthritis","up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls","up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls","11q12.2","FADS1, FADS2, FADS3","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs968567-C","rs968567",0,968567,"5_prime_UTR_variant",0,0.83,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",1.12,"[1.07-1.16]","Affymetrix, Illumina [up to 9739303] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-28",30254083,"Cousminer DL","2018-09-25","Diabetes Care","www.ncbi.nlm.nih.gov/pubmed/30254083","First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.","Latent autoimmune diabetes vs. type 2 diabetes","2,779 European ancestry latent autoimmune diabetes cases, 10,396 European ancestry type 2 diabetes cases","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,0.52,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.24,"[1.151-1.336]","Affymetrix, Illumina [8328843] (imputed)","N"]
[34,"rs7970695",12,121403724,"rs7953249","2011-01-15",21203500,"Lauc G","2010-12-23","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21203500","Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.","N-glycan levels","2,559 European ancestry individuals","NA","12q24.31","OASL, C12orf43, HNF1A","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.45,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(DG7)",0.17,"[0.11-0.23] unit decrease","Illumina [~ 300000]","N"]
[34,"rs7970695",12,121439433,"rs1169310","2008-09-08",18439552,"Reiner AP","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439552","Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.","C-reactive protein","909 European ancestry individuals","5,106 European ancestry individuals","12q24.31","HNF1A","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs1169310-A","rs1169310",0,1169310,"3_prime_UTR_variant",0,0.38,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.13,"[0.08-0.17] mg/l decrease in log(CRP) level","Illumina [317000]","N"]
[37,"rs12438999",15,58687880,"rs493258","2010-05-06",20385826,"Neale BM","2010-04-12","Proc Natl Acad Sci U S A","www.ncbi.nlm.nih.gov/pubmed/20385826","Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).","Age-related macular degeneration","979 cases, 1,709 controls","868 European ancestry cases, 410 European ancestry controls, 4,921 cases, 3,824 controls","15q21.3","intergenic","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs493258-C","rs493258",0,493258,"intron_variant",0,0.55,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.16,"[1.10-1.22]","Affymetrix [632932]","N"]
[38,"rs247617",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.643,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(AA)",0.126,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","CYP2A6","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-T","rs56113850",0,56113850,"intron_variant",0,0.458,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.067,"NR unit increase","Illumina [NR] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2013-02-28",23207651,"Davies G","2012-12-04","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/23207651","A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.","Cognitive decline","3,280 European ancestry individuals","1,367 European ancestry individuals","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.2,"[0.12-0.28] unit decrease","Illumina [549692]","N"]
[47,"rs8111874",19,49206417,"rs492602","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-A","rs492602",0,492602,"synonymous_variant",0,0.518,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs2179372",20,39950805,"rs2866611","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","20q12","NR","ZHX3 - ADI1P1","ENSG00000174306","ENSG00000235102",null,4493,8958,"rs2866611-?","rs2866611",0,2866611,"regulatory_region_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs585967",2,21270554,"rs585967","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,3609,76235,"rs585967-C","rs585967",0,585967,"regulatory_region_variant",1,0.844,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.07,"[1.04-1.09]","Affymetrix [9149595] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs13013484",2,28020157,"rs12623170","2017-11-10",28991256,"Li Z","2017-10-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28991256","Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.","Schizophrenia","7,699 Chinese ancestry cases, 35,476 European ancestry cases, 18,327 Chinese ancestry controls, 46,839 European ancestry controls","4,384 Chinese ancestry cases, 5,770 Chinese ancestry controls","2p23.2","RBKS","RBKS, MRPL33",null,null,"ENSG00000171174, ENSG00000243147",null,null,"rs12623170-C","rs12623170",0,12623170,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.0604454,"[1.04-1.08]","Affymetrix, Illumina [up to 5107227] (imputed)","N"]
[16,"rs1233489",6,29144532,"rs145283874","2018-09-20",29808027,"Tedja MS","2018-05-28","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29808027","Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.","Myopia (age of diagnosis)","104,293 European ancestry individuals","NA","6p22.1","NR","OR2J2 - OR2J4P","ENSG00000226000","ENSG00000218297",null,944,4755,"rs145283874-T","rs145283874",1,9257566,"intergenic_variant",1,0.1019,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.0629,"[0.041-0.085] unit decrease","Illumina [~ 10600000] (imputed)","N"]
[19,"rs34121855",7,72856430,"rs1178979","2018-08-16",28082259,"Pankow JS","2017-01-12","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/28082259","Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).","Protein C levels","10,778 European ancestry individuals, 2,706 African American individuals","NA","7q11.23","BAZIB","BAZ1B",null,null,"ENSG00000009954",null,null,"rs1178979-C","rs1178979",0,1178979,"3_prime_UTR_variant",0,0.19,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(EA)",0.06,"[NR] μg/mL decrease","Affymetrix [at least 22484459] (imputed)","N"]
[19,"rs34121855",7,72904810,"rs17145713","2010-09-28",20802025,"Tang W","2010-08-27","Blood","www.ncbi.nlm.nih.gov/pubmed/20802025","Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.","Protein C levels","8,048 European ancestry individuals","1,376 European ancestry individuals","7q11.23","BAZ1B","BAZ1B",null,null,"ENSG00000009954",null,null,"rs17145713-T","rs17145713",0,17145713,"intron_variant",0,0.2,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.06,"[0.04-0.08] ug/ml decrease","Affymetrix [2461269]","N"]
[26,"rs2740488",9,107661742,"rs2740488","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-C","rs2740488",0,2740488,"intron_variant",0,0.2745,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.06913026,"[0.045-0.093] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[27,"rs115478735",9,136154867,"rs495828","2010-02-02",20066004,"Chung CM","2010-01-12","Pharmacogenomics J","www.ncbi.nlm.nih.gov/pubmed/20066004","A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.","Angiotensin-converting enzyme activity","400 Han Chinese ancestry hypertensive cases","623 Han Chinese ancestry hypertensive cases","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-A","rs495828",0,495828,"regulatory_region_variant",1,0.17,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,4.9,"[NR] % variance","Illumina [~ 550000]","N"]
[30,"rs174564",11,61593816,"rs174568","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Serum metabolite concentrations in chronic kidney disease","1,143 European ancestry cases","NA","11q12.2","FADS1, FADS2","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174568-T","rs174568",0,174568,"missense_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Phosphatidylcholine with diacyl residue sum C34:4)",0.237543,"[0.15-0.32] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2014-11-21",24850809,"Verweij N","2014-05-21","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24850809","Genetic determinants of P wave duration and PR segment.","P wave duration","16,468 European ancestry individuals","NA","11q12.2","C11orf9, FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-A","rs174577",0,174577,"intron_variant",0,0.334,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.735,"[0.48-0.99] unit decrease","Illumina [2300000] (imputed)","N"]
[33,"rs35350651",12,111932800,"rs7137828","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental age at death)","208,118 British ancestry individuals","NA","12q24.12","SH2B3, ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[38,"rs247617",16,56987765,"rs56228609","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","16q13","CETP, HERPUD1","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8990,7997,"rs56228609-T","rs56228609",0,56228609,"intergenic_variant",1,0.303,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.039,"[0.025-0.053] unit decrease","Affymetrix [7947838] (imputed)","N"]
[44,"rs58542926",19,19658472,"rs16996148","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.11","CILP2, PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-T","rs16996148",0,16996148,"intergenic_variant",1,0.1,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.1,"[0.06-0.14] unit decrease","Affymetrix [389878]","N"]
[44,"19:19756073_AGCC_A",19,19786099,"rs58434384","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","19p13.11",null,"ZNF101",null,null,"ENSG00000181896",null,null,"rs58434384-?","rs58434384",0,58434384,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs2238681",19,45403412,"rs1160985","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs1160985-C","rs1160985",0,1160985,"intron_variant",0,0.563262,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(males)",1.629703,"[1.37-1.89]","Affymetrix, Illumina [2928658] (imputed)","N"]
[3,"rs11206510",1,55496039,"rs11206510","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","1p32.3","PCSK9","BSND - PCSK9","ENSG00000162399","ENSG00000169174",null,18582,9182,"rs11206510-C","rs11206510",0,11206510,"intergenic_variant",1,0.19,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.09,"[0.05-0.13] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[8,"rs6544366",2,21206183,"rs6754295","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,121650,16002,"rs6754295-C","rs6754295",0,6754295,"intergenic_variant",1,0.25,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[18,"rs16891156",6,160598596,"rs9456508","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","6q25.3","NR","SLC22A2",null,null,"ENSG00000112499",null,null,"rs9456508-T","rs9456508",0,9456508,"intron_variant",0,0.978225,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.0425855,"[0.028-0.058] unit decrease","Affymetrix [11535925] (imputed)","N"]
[19,"rs34121855",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(EA)",0.0319,"[0.021-0.043] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[26,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,0.748,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(EA)",0.027,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Triglycerides-Blood Pressure (TG-BP)","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-C","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.37,"[0.23-0.51] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs11282820",12,109878115,"rs7973253","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Menarche (age at onset)","approximately 242,000 European ancestry individuals","NA","12q24.11",null,"MYO1H",null,null,"ENSG00000174527",null,null,"rs7973253-?","rs7973253",0,7973253,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[34,"rs7970695",12,121438844,"rs735396","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.4,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(GP15)",0.14734995,"[0.095-0.2] (zscore) increase","Illumina [NR]","N"]
[46,"rs75627662",19,45413576,"rs75627662","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-T","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,0.23,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.08,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.655,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(Hispanic)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.607,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(Hispanic)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,29260431,"rs3117425","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling nervous","373,121 European ancestry individuals","NA","6p22.1","ZNF391","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3117425-T","rs3117425",0,3117425,"non_coding_transcript_exon_variant",0,0.119369,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,5.47,"z score decrease","NR [10847151] (imputed)","N"]
[24,"rs2954038",8,126507308,"rs2980888","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","8q24.13","Intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980888-T","rs2980888",0,2980888,"intron_variant",0,0.285,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0506,"[NR] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2017-08-21",28334935,"Raffield LM","2017-05-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334935","Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?","Iron status biomarkers (total iron binding capacity)","12,586 Hispanic/Latino individuals","NA","11q12.2","MYRF","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.099,"unit decrease","Illumina [27700000] (imputed)","N"]
[31,"rs473172",11,116732512,"rs2075292","2008-06-16",18193046,"Kooner JS","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193046","Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.","Triglycerides","1,005 European ancestry male individuals, 1,006 Indian Asian ancestry male individuals","6,827 European ancestry individuals, 2,528 Mexican ancestry individuals, 1,181 Indian Asian ancestry female individuals","11q23.3","LOC645044, APOA1, KIAA0999","SIK3",null,null,"ENSG00000160584",null,null,"rs2075292-G","rs2075292",0,2075292,"intron_variant",0,0.24,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,8.7,"[5.76-11.64] % increase","Perlegen [up to 216774]","N"]
[46,"rs10401176",19,45253491,"rs10401176","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCL3",null,null,"ENSG00000069399",null,null,"rs10401176-?","rs10401176",0,10401176,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs149214960",19,45327309,"rs10412413","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,2631,22123,"rs10412413-?","rs10412413",0,10412413,"intergenic_variant",1,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs566486324",19,45352804,"rs4802240","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs4802240-?","rs4802240",0,4802240,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs2972558",19,45356141,"rs2972558","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs2972558-?","rs2972558",0,2972558,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs41290120",19,45382675,"rs41290120","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs41290120-?","rs41290120",0,41290120,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs11668327",19,45398633,"rs11668327","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs11668327-?","rs11668327",0,11668327,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs59325138",19,45416291,"rs59325138","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs59325138-?","rs59325138",0,59325138,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[46,"rs5112",19,45431658,"rs8106813","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1P1",null,null,"ENSG00000214855",null,null,"rs8106813-?","rs8106813",0,8106813,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[47,"rs8111874",19,49206985,"rs602662","2016-08-31",26301688,"Li YR","2015-08-24","Nat Med","www.ncbi.nlm.nih.gov/pubmed/26301688","Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.","Pediatric autoimmune diseases","97 European ancestry thyroiditis cases, 107 European ancestry ankylosing spondylitis cases, 100 European ancestry psoriasis cases, 173 European ancestry celiac disease cases, 254 European ancestry systemic lupus erythematosus cases, 308 European ancestry common variable inmunodeficiency cases, 865 European ancestry ulcerative colitis cases, 1,086 European ancestry Type 1 diabetes cases, 1,123  European ancestry juvenile idiopathic arthritis cases, 1,922  European ancestry Crohn's disease cases, 10,718 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs602662-G","rs602662",0,602662,"missense_variant",0,0.49,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Illumina [7347414] (imputed)","N"]
[8,"rs432483",2,21428049,"rs312053","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","2p24.1",null,"AC067959.1 - AC018742.1","ENSG00000271629","ENSG00000233005",null,6281,15998,"rs312053-?","rs312053",0,312053,"intergenic_variant",1,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[19,"rs34121855",7,73005776,"rs35866503","2019-03-26",30642921,"de Vries PS","2019-01-14","Blood","www.ncbi.nlm.nih.gov/pubmed/30642921","A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.","Factor VII activity","20,014 European ancestry individuals, 3,420 African American individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,12655,1748,"rs35866503-C","rs35866503",0,35866503,"intergenic_variant",1,0.82,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.015,"[0.0091-0.0209] unit increase","Affymetrix, Illumina [10044948] (imputed)","N"]
[21,"rs2409784",8,11433909,"rs2898290","2017-09-22",28739976,"Wain LV","2017-07-24","Hypertension","www.ncbi.nlm.nih.gov/pubmed/28739976","Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.","Systolic blood pressure","150,134 European ancestry individuals","87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals","8p23.1","BLK, GATA4","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-C","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,0.525,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(EA, initial)",0.39,"[0.25-0.53] unit decrease","Affymetrix, Illumina, Perlegen [7994604] (imputed)","N"]
[31,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.293,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(EA)",0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58678512,"rs10468017","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(HDLC-WC)",0.16,"[0.10-0.22] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[47,"rs8111874",19,49213504,"rs2452170","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2 - MAMSTR","ENSG00000176920","ENSG00000176909",null,4297,2495,"rs2452170-G","rs2452170",0,2452170,"intergenic_variant",1,0.497,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(EA)",0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs548179580",1,25775733,"rs12027135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","MACO1",null,null,"ENSG00000204178",null,null,"rs12027135-A","rs12027135",0,12027135,"intron_variant",0,0.461,{"v":7e-08,"d":"7.00E-08"},7.15490195998574,"(EA)",0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,29548089,"rs926552","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Diastolic blood pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","154,543 European ancestry individuals, 26,183 South Asian ancestry individuals","6p22.1","SNORD32B","GABBR1, GABBR1, GABBR1, GABBR1, GABBR1, GABBR1, GABBR1",null,null,"ENSG00000232569, ENSG00000206511, ENSG00000204681, ENSG00000232632, ENSG00000237051, ENSG00000206466, ENSG00000237112",null,null,"rs926552-T","rs926552",0,926552,"intron_variant",0,0.111,{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.26,"[0.16-0.36] unit decrease","Illumina [247039]","N"]
[20,"rs1461729",8,9183596,"rs4841132","2017-08-21",28334935,"Raffield LM","2017-05-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334935","Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?","Iron status biomarkers (total iron binding capacity)","12,586 Hispanic/Latino individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.116,"unit decrease","Illumina [27700000] (imputed)","N"]
[2,"rs548179580",1,25768937,"rs10903129","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","MACO1",null,null,"ENSG00000204178",null,null,"rs10903129-A","rs10903129",0,10903129,"intron_variant",0,0.459,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(EA)",0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-03-28",30510157,"Franceschini N","2018-12-03","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30510157","GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.","Carotid intima media thickness","Up to 71,128 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.18,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.0487,"[0.047-0.05] unit decrease","Affymetrix, Illumina [9574088] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women","up to 62,368 European ancestry women","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.876,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.0264,"[0.017-0.036] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[33,"rs35350651",12,111833788,"rs10774624","2019-01-25",30423114,"Laufer VA","2018-11-13","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30423114","Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.","Rheumatoid arthritis","916 African American cases, 1,392 African American controls,","4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls","12q24.12","SH2B3, PTPN11","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-A","rs10774624",0,10774624,"intron_variant",0,"NR",{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.17559,"[-0.06944-0.42062] unit decrease","Illumina [8380626] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2012-08-08",22694956,"Cipriani V","2012-06-13","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/22694956","Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.","Age-related macular degeneration","893 European ancestry cases, 2,199 European ancestry controls","1,411 European ancestry cases, 1,431 European ancestry controls","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.851,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,1.37,"[1.22-1.54]","Illumina [2272849] (imputed)","N"]
[2,"rs548179580",1,25747230,"rs586178","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","RHCE",null,null,"ENSG00000188672",null,null,"rs586178-G","rs586178",0,586178,"missense_variant",0,"NR",{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,0.026,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1233489",6,28974265,"rs115287935","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","ZNF311, LOC100129636","ZNF311 - OR2AD1P","ENSG00000197935","ENSG00000233650",null,1172,20192,"rs115287935-T","rs115287935",1,3129794,"intergenic_variant",1,0.08238902,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,1.1647499,"[1.101314463-1.231839236]","Illumina [10439017] (imputed)","N"]
[28,"rs148063610",10,46018831,"rs11239549","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q11.22","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239549-A","rs11239549",0,11239549,"intron_variant",0,0.763,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(EA)",0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.1978,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,0.077,"[0.05-0.104] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[1,"rs534417",1,23755513,"rs1198430","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p36.12","ASAP3","ASAP3",null,null,"ENSG00000088280",null,null,"rs1198430-T","rs1198430",0,1198430,"3_prime_UTR_variant",0,0.104,{"v":1e-07,"d":"1.00E-07"},7,"(Trans-ethnic initial)",0.0269,"[0.016-0.038] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[18,"rs56393506",6,161089307,"rs56393506","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (large artery atherosclerosis)","4,373 European ancestry cases, 406,111 European ancestry controls, 1,626 East Asian ancestry cases, 28,195 East Asian ancestry controls, 355 South Asian ancestry cases, 6,707 South Asian ancestry controls, 259 African American cases, 15,146 African American controls, 34 Asian ancestry cases, 333 Asian ancestry controls, 41 Latin American cases, 692 Latin American controls","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,0.16,{"v":1e-07,"d":"1.00E-07"},7,null,1.17,"[1.10-1.24]","NR [~ 8000000] (imputed)","N"]
[20,"rs2976940",8,8307643,"rs2921073","2017-10-24",28892059,"Chang D","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892059","A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.","Parkinson's disease","20,184 European ancestry cases, 397,324 European ancestry controls","5,851 European ancestry cases, 5,866 European ancestry controls","8p23.1","NR","AC103957.1 - AC103957.2","ENSG00000253505","ENSG00000254153",null,25493,6776,"rs2921073-C","rs2921073",0,2921073,"intergenic_variant",1,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,1.0615711,"[1.04-1.08]","Illumina [11933700] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5,{"v":1e-07,"d":"1.00E-07"},7,null,0.02,"[0.01-0.03] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.529,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":1e-07,"d":"1.00E-07"},7,"(men)",0.0254,"[0.016-0.035] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[30,"rs2727263",11,61616012,"rs2851682","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2851682-A","rs2851682",0,2851682,"intron_variant",0,0.9123,{"v":1e-07,"d":"1.00E-07"},7,"(Cis/trans-18:2, EA)",0.0039,"[0.0025-0.0053] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs11216206",11,116791307,"rs78692246","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","11q23.3",null,"SIK3",null,null,"ENSG00000160584",null,null,"rs78692246-?","rs78692246",0,78692246,"intron_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[33,"rs35350651",12,112486818,"rs17696736","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.13","NR","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,0.023,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.676,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[44,"19:19756073_AGCC_A",19,19793545,"rs56408111","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","19p13.11",null,"ZNF101",null,null,"ENSG00000181896",null,null,"rs56408111-?","rs56408111",0,56408111,"3_prime_UTR_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[46,"rs157580",19,45395266,"rs157580","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,null,{"v":1e-07,"d":"1.00E-07"},7,null,0.006314825,"[NR] unit increase","Illumina [575353]","N"]
[46,"rs429358",19,45411941,"rs429358","2010-02-12",20100581,"Shen L","2010-01-22","Neuroimage","www.ncbi.nlm.nih.gov/pubmed/20100581","Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort.","Brain imaging","175 European ancestry Alzheimer cases, 354 European ancestry amnestic mild cognitive impairment cases, 204 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,"(multiple phenotypes)",null,null,"Illumina [530992]","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.629,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232195,"rs693","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs693-A","rs693",0,693,"synonymous_variant",0,0.48,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.08,"[0.04-0.12] unit increase","Affymetrix [389878]","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-05-12",27911795,"Schumann G","2016-11-28","Proc Natl Acad Sci U S A","www.ncbi.nlm.nih.gov/pubmed/27911795","KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.","Alcohol consumption","up to 70,460 European ancestry drinker individuals","up to 35,438 European ancestry drinker individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.0102,"[0.0065-0.0139] unit decrease","Affymetrix, Illumina, Perlegen [at least 316407] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-08-03",28485404,"Jorgenson E","2017-05-09","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28485404","Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.","Alcohol consumption (drinks per week)","23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.          ","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.41,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.034,"unit decrease","Affymetrix [NR] (imputed)","N"]
[13,"rs56912706",5,75038718,"rs258494","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","5q13.3","POC5, SV2C","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,25412,9677,"rs258494-C","rs258494",0,258494,"intergenic_variant",1,null,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.212,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[20,"rs1461729",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19876746,"rs7016880","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,51976,59879,"rs7016880-?","rs7016880",0,7016880,"intergenic_variant",1,0.9,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,3.13,"[2.04-4.76]","Affymetrix [~ 2100000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47669175,"rs59360790","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Body fat percentage","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","11p11.2","NR","MTCH2 - AGBL2","ENSG00000109919","ENSG00000165923",null,5000,11968,"rs59360790-?","rs59360790",0,59360790,"intergenic_variant",1,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(female)",0.18308,"[0.11-0.25] unit increase","Affymetrix [7794483] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.225,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(South Asian)",0.339,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs11600380",11,116665079,"rs9804646","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-C","rs9804646",0,9804646,"intergenic_variant",1,0.911,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,112486818,"rs17696736","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.13","NR","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,0.553,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,0.984,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(AA)",0.482,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,0.674,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.021,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs2238681",19,45410444,"rs769450","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769450-G","rs769450",0,769450,"non_coding_transcript_exon_variant",0,0.610827,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(males)",1.600702,"[1.34-1.86]","Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(East Asian)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49171306,"rs12462111","2017-02-19",27559109,"Bustamante M","2016-08-23","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/27559109","A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways.","diarrhoeal disease at age 2 with doctor diagnosis","990 European ancestry cases, 5,243 European ancestry controls","1,274 European ancestry cases, 6,448 European ancestry controls","19q13.33","NTN5","NTN5, SEC1P",null,null,"ENSG00000142233, ENSG00000232871",null,null,"rs12462111-C","rs12462111",0,12462111,"intron_variant",0,0.57,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,1.23,"[1.14-1.33]","Affymetrix, Illumina [at least 5400000] (imputed)","N"]
[8,"rs6544366",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.754,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Hispanic)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs56912706",5,75034387,"rs7715806","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,21081,14008,"rs7715806-C","rs7715806",0,7715806,"intergenic_variant",1,0.6097,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(men)",0.0314,"[0.019-0.044] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,0.793,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(East Asian)",0.101,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-A","rs7124681",0,7124681,"intron_variant",0,0.4018,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(women)",0.0235,"[0.014-0.033] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.878,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(APOC3)",0.194,"[0.12-0.27] unit decrease","Illumina [> 1000000] (imputed)","N"]
[33,"rs35350651",12,112591686,"rs17630235","2018-06-29",28714469,"Langefeld CD","2017-07-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28714469","Transancestral mapping and genetic load in systemic lupus erythematosus.","Systemic lupus erythematosus","6,748 European ancestry cases, 11,516 European ancestry controls, 2,970 African American cases, 2,452 African American controls, 1,872 Hispanic cases, 2,016 Hispanic controls","NA","12q24.13","TRAFD1, C12orf51","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-T","rs17630235",0,17630235,"intergenic_variant",1,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,1.12,"[1.06-1.18]","Illumina [at least 5000000] (imputed)","N"]
[42,"rs1320700",18,47107152,"rs12970066","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs12970066-C","rs12970066",0,12970066,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs58542926",19,19407718,"rs10401969","2015-06-11",25246029,"DiStefano JK","2014-09-23","Acta Diabetol","www.ncbi.nlm.nih.gov/pubmed/25246029","Genome-wide analysis of hepatic lipid content in extreme obesity.","Hepatic lipid content in extreme obesity","1,868 European ancestry cases","NA","19p13.11","SUGP1","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-?","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,{"$nulls":3},"Illumina [605718]","N"]
[46,"rs11556505",19,45395619,"rs2075650","2010-11-23",20932310,"Han MR","2010-10-08","BMC Neurol","www.ncbi.nlm.nih.gov/pubmed/20932310","Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.","Cerebrospinal fluid AB1-42 levels","172 European ancestry Alzheimer's disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Controls)",null,null,"Illumina [498205]","N"]
[8,"rs6544366",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.244,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(Hispanic)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs11250098",8,11078781,"rs4512344","2017-07-14",28472463,"Mullin BH","2017-05-04","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28472463","Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation.","Bone ultrasound measurement (broadband ultrasound attenuation)","1,268 whole genome sequenced European ancestry women, 8,880 European ancestry women, 6,479 European ancestry men","NA","8p23.1","XKR6, MTMR9","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,17601,26354,"rs4512344-A","rs4512344",0,4512344,"regulatory_region_variant",1,0.49,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.06,"[0.04-0.08] unit increase","Illumina [11973598] (imputed)","N"]
[26,"rs1800978",9,107665978,"rs1800978","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.8664,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.0438,"[0.027-0.061] unit increase","NR [8041861] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2010-09-13",20694148,"Zabaneh D","2010-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20694148","A genome-wide association study of the metabolic syndrome in Indian Asian men.","Metabolic syndrome","2,554 Indian Asian ancestry individuals","2,240 Indian Asian ancestry individuals","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-G","rs1535",0,1535,"intron_variant",0,0.18,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(HDL)",0.03,"[0.02-0.04] mmol/l decrease","Illumina [308011]","N"]
[33,"rs35350651",12,112486818,"rs17696736","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.13","NR","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.023,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41346768,"rs2316205","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1/FVC ratio","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","Intergenic","AC008537.1, AC008537.3",null,null,"ENSG00000268797, ENSG00000279108",null,null,"rs2316205-T","rs2316205",0,2316205,"non_coding_transcript_exon_variant",0,0.549,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.012,"unit increase","Illumina [NR] (imputed)","N"]
[46,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206674,"rs601338","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Number of common colds","43,826 European ancestry cases, 15,720 European ancestry controls","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs601338-?","rs601338",0,601338,"stop_gained",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.0198,"[0.012-0.027] unit increase","Illumina [at least 560000] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.675,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs10455872",6,161010118,"rs10455872","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (father's age at death)","317,652 British ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.92,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.0247,"[0.015-0.034] unit increase","Affymetrix [11535925] (imputed)","N"]
[21,"rs11250098",8,10802146,"rs12546366","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (arm fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs12546366-T","rs12546366",0,12546366,"intron_variant",0,0.4529,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(males)",0.01806,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2017-10-24",28898252,"Wheeler E","2017-09-12","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/28898252","Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.","Glycated hemoglobin levels","88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals","33,238 European ancestry individuals,  2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,0.6485,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(European)",0.0083,"[0.005-0.0116] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[36,"rs6602911",13,114544024,"rs7140110","2017-02-24",27036123,"van Leeuwen EM","2016-04-01","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/27036123","Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.","Triglycerides","41,142 European ancestry individuals, 705 East Asian ancestry individuals, 6,287 African American individuals, 1,415 Hispanic individuals","60,827 European ancestry individuals, 9,982 Indian Asian ancestry individuals, 2,710 African American/Afro-Caribbean individuals","13q34","GAS6","GAS6-AS1, GAS6",null,null,"ENSG00000233695, ENSG00000183087",null,null,"rs7140110-T","rs7140110",0,7140110,"non_coding_transcript_exon_variant",0,0.72,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.015,"[0.0091-0.0209] unit decrease","Affymetrix, Illumina [NR] (imputed)","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.906,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.028,"[0.017-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[45,"rs56113850",19,41341229,"rs12461964","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1/FVC ratio","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","Intergenic","AC008537.1, AC008537.2",null,null,"ENSG00000268797, ENSG00000269843",null,null,"rs12461964-A","rs12461964",0,12461964,"intron_variant",0,0.551,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.011,"unit increase","Illumina [NR] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Gondoic acid (20:1n-9) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.412,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",2E-3,"[0.002-0.002] unit decrease","Affymetrix, Illumina [2200000] (imputed)","N"]
[19,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.906,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(East Asian)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (cardioembolic)","7,193 European ancestry cases, 406,111 European ancestry controls, 847 East Asian ancestry cases, 28,195 East Asian ancestry controls, 422 South Asian ancestry cases, 6,707 South Asian ancestry controls, 414 African American cases, 15,146 African American controls, 31 Asian ancestry cases, 333 Asian ancestry controls, 99 Latin American cases, 692 Latin American controls","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[30,"rs174564",11,61557803,"rs102275","2010-09-13",20694148,"Zabaneh D","2010-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20694148","A genome-wide association study of the metabolic syndrome in Indian Asian men.","Metabolic syndrome","2,554 Indian Asian ancestry individuals","2,240 Indian Asian ancestry individuals","11q12.2","C11orf10","TMEM258",null,null,"ENSG00000134825",null,null,"rs102275-?","rs102275",0,102275,"non_coding_transcript_exon_variant",0,0.2,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(HDL)",null,null,"Illumina [308011]","N"]
[45,"rs56113850",19,41359996,"rs3875149","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","Intergenic","AC008537.1",null,null,"ENSG00000268797",null,null,"rs3875149-A","rs3875149",0,3875149,"intron_variant",0,0.386,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,null,0.061,"NR unit increase","Illumina [NR] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.656,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs253412",5,75015242,"rs2112347","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Body mass index (joint analysis main effects and smoking interaction)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","5q13.3","C5orf37","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.6128,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(women)",null,null,"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[24,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.647,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs35120633",11,116603724,"rs12272004","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,74756,15162,"rs12272004-C","rs12272004",0,12272004,"TF_binding_site_variant",1,0.93,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,0.11,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[45,"rs56113850",19,41357910,"rs57837628","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1/FVC ratio","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","Intergenic","AC008537.1",null,null,"ENSG00000268797",null,null,"rs57837628-A","rs57837628",0,57837628,"intron_variant",0,0.542,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,0.014,"unit increase","Illumina [NR] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.639,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(Hispanic)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2016-11-25",26833098,"Kilpelainen TO","2016-02-01","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26833098","Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.","circulating leptin levels","14,586 European ancestry men, 20,706 European ancestry women","8,554 European ancestry men, 8,337 European ancestry women","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-C","rs780093",0,780093,"intron_variant",0,0.61,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(women)",0.033,"[0.019-0.047] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[24,"rs2954021",8,126486409,"rs17321515","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-A","rs17321515",0,17321515,"intron_variant",0,0.47,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(LDL)",0.07,"mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[31,"rs688456",11,116728630,"rs12225230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs12225230-G","rs12225230",0,12225230,"missense_variant",0,0.823,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(EA)",0.027,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.091,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(East Asian)",0.146,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Valine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,0.05,"[0.024-0.076] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[28,"rs148063610",10,46013277,"rs970548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10q11.22","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs970548-A","rs970548",0,970548,"intron_variant",0,0.757,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(EA)",0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs2238681",19,45398264,"rs157588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157588-C","rs157588",0,157588,"intron_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,null,0.017,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[52,"rs372038686",23,109939205,"rs5943057","2011-04-11",21378988,"Coronary Artery Disease (C4D) Genetics Consortium","2011-03-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21378988","A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.","Coronary heart disease","8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls","18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls","Xq23","intergenic","CHRDL1",null,null,"ENSG00000101938",null,null,"rs5943057-?","rs5943057",0,5943057,"intron_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,{"$nulls":3},"Illumina [574919]","N"]
[9,"rs1260326",2,27598097,"rs4665972","2012-08-20",22747683,"Eriksson N","2012-06-30","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/22747683","Genetic variants associated with breast size also influence breast cancer risk.","Breast size","16,175 European ancestry female individuals","NA","2p23.3","SLC4A1AP, GCKR","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-T","rs4665972",0,4665972,"intron_variant",0,0.448,{"v":1e-06,"d":"1.00E-06"},6,null,0.08,"[0.047-0.113] cup size increase","Illumina [7422970] (imputed)","N"]
[9,"rs145508558",2,27844601,"rs1881396","2018-02-20",29385134,"Kawaguchi T","2018-01-31","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29385134","Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.","Nonalcoholic fatty liver disease","902 Japanese ancestry cases, 7,672 Japanese ancestry controls","NA","2p23.3","ZNF512, GPN1","ZNF512, AC074091.1",null,null,"ENSG00000243943, ENSG00000259080",null,null,"rs1881396-T","rs1881396",0,1881396,"3_prime_UTR_variant",0,0.71,{"v":1e-06,"d":"1.00E-06"},6,null,1.34,"[1.19-1.50]","Illumina [93606]","N"]
[13,"rs4704210",5,74648603,"rs12654264","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","5q13.3","MGGCR","HMGCR",null,null,"ENSG00000113161",null,null,"rs12654264-?","rs12654264",0,12654264,"intron_variant",0,null,{"v":1e-06,"d":"1.00E-06"},6,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[18,"rs10455872",6,160997118,"rs74617384","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (combined parental age at death)","45,627 middle-aged British individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-?","rs74617384",0,74617384,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.06755,"[0.041-0.095] unit increase","Affymetrix [9658292] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72856269,"rs2240466","2011-05-26",21490707,"Cornelis MC","2011-04-07","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21490707","Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.","Caffeine consumption","47,431 European ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2240466-A","rs2240466",0,2240466,"3_prime_UTR_variant",0,0.12,{"v":1e-06,"d":"1.00E-06"},6,null,0.1109,"[0.07-0.15] mg/day increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs1692821",8,11698747,"rs1296028","2012-04-20",22451204,"Pankratz N","2012-03-01","Ann Neurol","www.ncbi.nlm.nih.gov/pubmed/22451204","Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.","Parkinson's disease","4,238 European ancestry cases, 4,239 European ancestry controls","3,738 European ancestry cases, 2,111 European ancestry controls","8p23.1","intergenic","FDFT1 - CTSB","ENSG00000079459","ENSG00000164733",null,1929,1286,"rs1296028-?","rs1296028",0,1296028,"regulatory_region_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,1.15,"[NR]","Illumina [2500000] (imputed)","N"]
[26,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",0.0395,"[0.024-0.055] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.505,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61579463,"rs174554","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174554-A","rs174554",0,174554,"intron_variant",0,0.506,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs565349424",12,112211833,"rs2238151","2013-01-09",23041239,"Traylor M","2012-10-05","Lancet Neurol","www.ncbi.nlm.nih.gov/pubmed/23041239","Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.","Stroke (ischemic)","12,389 European ancestry cases, 62,004 European ancestry controls","1,322 Pakistani ancestry cases, 1,143 Pakistani ancestry controls, 12,025 European ancestry cases, 27,940 European ancestry controls","12q24.12","ALDH2","ALDH2, AC002996.1",null,null,"ENSG00000111275, ENSG00000257767",null,null,"rs2238151-T","rs2238151",0,2238151,"intron_variant",0,0.66,{"v":1e-06,"d":"1.00E-06"},6,"(FS)",1.13,"[1.08-1.19]","Affymetrix, Illumina [NR] (imputed)","N"]
[37,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.588,{"v":1e-06,"d":"1.00E-06"},6,"(East Asian)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41347998,"rs60446182","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1/FVC ratio","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","Intergenic","AC008537.1",null,null,"ENSG00000268797",null,null,"rs60446182-A","rs60446182",1,4001925,"intron_variant",0,0.55,{"v":1e-06,"d":"1.00E-06"},6,null,0.011,"unit increase","Illumina [NR] (imputed)","N"]
[45,"rs56113850",19,41353107,"rs56113850","2015-04-02",25006744,"Castaldi PJ","2014-07-09","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/25006744","Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.","Local histogram emphysema pattern","3,732 European ancestry smoker individuals, 2,724 European ancestry chronic obstructive pulmonary disease smoker cases, 2,372 African American smoker individuals, 786 African American chronic obstructive pulmonary disease smoker cases","NA","19q13.2","CYP2A6","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-T","rs56113850",0,56113850,"intron_variant",0,0.4,{"v":1e-06,"d":"1.00E-06"},6,"(Moderate Centrilobular, EA)",0.02,"[0.012-0.028] unit decrease","Illumina [6942916] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(p-tau181p/AB1-42, t-tau/AB1-42)",null,null,"Illumina [322557]","N"]
[46,"rs157595",19,45414451,"rs439401","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","LOC100129500","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-?","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(AB1-42)",null,null,"Illumina [322557]","N"]
[52,"rs372038686",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.015,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs548179580",1,25747230,"rs586178","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","RHCE",null,null,"ENSG00000188672",null,null,"rs586178-G","rs586178",0,586178,"missense_variant",0,0.555,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA)",0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[12,"rs59950280",4,3452345,"rs59950280","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","4p16.3","HGFAC","HGFAC - DOK7","ENSG00000109758","ENSG00000175920",null,1123,12693,"rs59950280-A","rs59950280",0,59950280,"intergenic_variant",1,0.341,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.033,"[0.019-0.047] unit increase","Affymetrix [7947838] (imputed)","N"]
[13,"rs56912706",5,75034387,"rs7715806","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Body mass index","up to 33,431 European ancestry individuals","NA","5q13.3","POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,21081,14008,"rs7715806-G","rs7715806",0,7715806,"intergenic_variant",1,0.385,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.6861,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[20,"rs1461729",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs1461729",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.689,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs56343119",9,136328657,"rs3124765","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","9q34.2","NR","CACFD1, CACFD1",null,null,"ENSG00000280479, ENSG00000160325",null,null,"rs3124765-C","rs3124765",0,3124765,"missense_variant",0,0.8475,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA)",0.0437,"[0.026-0.062] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-T","rs174551",0,174551,"5_prime_UTR_variant",0,0.454,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"11:61625723_CA_C",11,61639573,"rs174448","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4747,1418,"rs174448-A","rs174448",0,174448,"regulatory_region_variant",1,0.6472,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Cis/trans-18:2, EA)",2E-3,"[0.0012-0.0028] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs11216275",11,116973929,"rs12269901","2018-07-19",29782485,"Rueger S","2018-05-21","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29782485","Evaluation and application of summary statistic imputation to discover new height-associated loci.","Height","253,288 European ancestry individuals","336,474 European ancestry individuals","11q23.3","NR","AP000936.1",null,null,"ENSG00000224077",null,null,"rs12269901-C","rs12269901",0,12269901,"intron_variant",0,0.290399365247289,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"NR [9276018] (imputed)","N"]
[42,"rs1320700",18,47093864,"rs2000813","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs2000813-T","rs2000813",0,2000813,"missense_variant",0,0.2959,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.033,"[0.019-0.047] unit decrease","NR [8041861] (imputed)","N"]
[43,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.986,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.33,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs566486324",19,45351746,"rs1871047","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","PVRL2","NECTIN2",null,null,"ENSG00000130202",null,null,"rs1871047-A","rs1871047",0,1871047,"intron_variant",0,0.619781,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.270037,"[1.15-1.39]","Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs2238681",19,45403412,"rs1160985","2017-03-31",27694959,"Bonder MJ","2016-10-03","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27694959","The effect of host genetics on the gut microbiome.","Gut microbiota (functional units)","984 European ancestry individuals","530 European ancestry individuals","19q13.32","TOMMC40, APOE","TOMM40",{"$nulls":5},"rs1160985-T","rs1160985",0,1160985,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(GO:0004812|MF|05|aminoacyl-tRNA ligase activity)",4.723705,"Z-score increase","Illumina [8100000] (imputed)","N"]
[46,"rs2238681",19,45403412,"rs1160985","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","Intergenic","TOMM40",{"$nulls":5},"rs1160985-?","rs1160985",0,1160985,"intron_variant",0,null,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.005514577,"[NR] unit increase","Illumina [575353]","N"]
[46,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,0.379,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(AA)",0.125,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.789,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(AA)",0.151,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.543,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","19q13.32","APOC2, APOE, APOC4, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.21,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(CRP)",0.28,"[NR] mg/L decrease","Affymetrix [408775]","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.99,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.439,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206172,"rs516246","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-A","rs516246",0,516246,"intron_variant",0,0.272,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Vitamin B12 )",0.03,"[NR] pmol/L increase","Illumina [899892]","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.371,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.067,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.018,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-03-31",27702941,"Cornelis MC","2016-10-03","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/27702941","Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.","Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio)","5,323 European ancestry individuals","824 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,4.69,"Z-score decrease","Illumina [~ 31000000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Palmitic acid (16:0) levels","8,961 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1261,"unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs145508558",2,27789861,"rs965813","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","AC109829.1","C2orf16",null,null,"ENSG00000221843",null,null,"rs965813-A","rs965813",0,965813,"missense_variant",0,0.333,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0415,"[0.024-0.059] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[13,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,0.446,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[13,"rs253412",5,74997756,"rs10057967","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","POC5",null,null,"ENSG00000152359",null,null,"rs10057967-?","rs10057967",0,10057967,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,{"$nulls":3},"Affymetrix [NR]","N"]
[13,"rs56912706",5,75003678,"rs2307111","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.597,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.03,"[1.02-1.05]","Affymetrix, Illumina [247470]","N"]
[16,"rs1233489",6,29153155,"rs3130746","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tuberculosis","4,426 European ancestry cases, 84,290 European ancestry controls","NA","6p22.1","NR","OR2J4P - AL645937.3","ENSG00000218297","ENSG00000230598",null,2933,27508,"rs3130746-?","rs3130746",0,3130746,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1783,"[0.1-0.25] unit increase","Illumina [at least 560000] (imputed)","N"]
[17,"rs114863007",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference adjusted for BMI","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.8425,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0298,"[0.017-0.042] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[18,"rs641990",6,160820978,"rs3105749","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A3",null,null,"ENSG00000146477",null,null,"rs3105749-G","rs3105749",0,3105749,"intron_variant",0,0.519,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[18,"rs641990",6,160820978,"rs3105749","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A3",null,null,"ENSG00000146477",null,null,"rs3105749-G","rs3105749",0,3105749,"intron_variant",0,0.519,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"7:73042302_GCTTT_G",7,72864869,"rs714052","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-?","rs714052",0,714052,"intron_variant",0,0.87,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,2.27,"[1.61-3.23]","Affymetrix [~ 2100000] (imputed)","N"]
[19,"rs34121855",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0351,"[0.02-0.05] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[19,"rs34121855",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.905,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs615632",8,9814411,"rs656319","2013-01-16",23049088,"Meng W","2012-10-09","Invest Ophthalmol Vis Sci","www.ncbi.nlm.nih.gov/pubmed/23049088","A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.","Myopia (pathological)","187 European ancestry cases, 1064 European ancestry controls",null,"8p23.1","intergenic","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,51535,93584,"rs656319-?","rs656319",0,656319,"intergenic_variant",1,0.549,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,null,"[NR]","Affymetrix, Illumina [152234]","N"]
[21,"rs2409784",8,11433909,"rs2898290","2018-09-14",27618452,"Ehret GB","2016-09-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618452","The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.","Diastolic blood pressure","up to 201,529 European ancestry individuals","up to 140,886 European ancestry individuals","8p23.1","BLK, GATA4","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.167,"[0.096-0.238] mm Hg increase","Affymetrix, Illumina, Perlegen [128272]","N"]
[22,"rs7816447",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.902,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.05,"[1.03-1.08]","Affymetrix, Illumina [247470]","N"]
[22,"rs7816447",8,19819724,"rs328","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","8p21.3","LPL","LPL",null,null,"ENSG00000175445",null,null,"rs328-C","rs328",0,328,"stop_gained",0,0.902,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.05,"[1.03-1.07]","Affymetrix, Illumina [247470]","N"]
[22,"rs7816447",8,19833156,"rs80073370","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Pulse pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8p21.3","LPL, SLC18A1","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,8386,103469,"rs80073370-A","rs80073370",0,80073370,"regulatory_region_variant",1,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.219,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[23,"rs6471717",8,59377357,"rs6471717","2017-03-10",27094239,"Joshi AD","2016-04-16","Gastroenterology","www.ncbi.nlm.nih.gov/pubmed/27094239","Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.","Gallstone disease","8,720 European ancestry cases,  55,152 European ancestry controls","6,489 European ancestry cases, 62,797 European ancestry controls, 1,499 African American cases, 9,145 African American controls, 1,056 Hispanic cases, 2,403 Hispanic controls","8q12.1","CYP7A1, UBXN2B","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,13297,25380,"rs6471717-G","rs6471717",0,6471717,"intergenic_variant",1,0.35,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",1.11,"[1.08–1.14]","Affymetrix, Illumina [at least 2305318] (imputed)","N"]
[24,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.045,"[0.025-0.065] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.551395,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.04,"[1.03- 1.06]","Affymetrix, Illumina [8600000] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs35309034",8,126498828,"rs4870941","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-?","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(male)",0.1938,"[0.11-0.28] unit decrease","Affymetrix [7794483] (imputed)","N"]
[24,"rs35309034",8,126504726,"rs6987702","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6987702-G","rs6987702",0,6987702,"intron_variant",0,0.29,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[26,"rs4149307",9,107591272,"rs2853579","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2853579-G","rs2853579",0,2853579,"synonymous_variant",0,0.874,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",0.033,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs56343119",9,136323754,"rs4962153","2017-03-31",27694959,"Bonder MJ","2016-10-03","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27694959","The effect of host genetics on the gut microbiome.","Gut microbiota (functional units)","984 European ancestry individuals","530 European ancestry individuals","9q34.2","ADAMTS13, CACFD1, SLC2A6","ADAMTS13, ADAMTS13",null,null,"ENSG00000281244, ENSG00000160323",null,null,"rs4962153-A","rs4962153",0,4962153,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(GO:0048598|BP|03|embryonic morphogenesis)",4.6572533,"Z-score decrease","Illumina [8100000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Body mass index (joint analysis main effects and smoking interaction)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(women)",null,null,"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.4106,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0225,"[0.013-0.032] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61609750,"rs174583","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","11q12.2","FADS1, FADS2, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-T","rs174583",0,174583,"intron_variant",0,0.34,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Triglyceride, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[30,"11:61625723_CA_C",11,61639488,"rs422249","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2 - FADS3","ENSG00000134824","ENSG00000221968",null,4662,1503,"rs422249-T","rs422249",0,422249,"regulatory_region_variant",1,0.3218,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Cis/trans-18:2, EA)",0.0021,"[0.0013-0.0029] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs651821",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.187,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(South Asian)",0.332,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs117709132",11,116936871,"rs56751865","2018-01-29",29198719,"Shaffer JR","2017-11-30","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29198719","Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment.","Lobe attachment (rater scored)","1791 European ancestry individuals, 5,062 Hispanic individuals, 2,857 Han Chinese ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs56751865-?","rs56751865",0,56751865,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Chinese)",0.1026,"[0.06-0.146] unit decrease","Illumina [at least 7383741] (imputed)","N"]
[31,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.028,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111932800,"rs7137828","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (both parents in top 10%)","7,182 cases, 79,767 controls","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[33,"rs35350651",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.266,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[37,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.888,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.64,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.612,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs55696635",15,58712203,"rs11857380","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs11857380-C","rs11857380",0,11857380,"5_prime_UTR_variant",0,0.131,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Weight )",0.03,"[NR] kg increase","Illumina [899892]","N"]
[37,"rs1077835",15,58723675,"rs1800588","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.41,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.078,"[0.045-0.111] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[38,"rs247617",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.709,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,56995236,"rs1800775","2017-11-01",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","Apolipoprotein A1 levels","1,451 European ancestry type 2 diabetes cases and controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.44,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.6,"(% variance) increase","Affymetrix [389878]","N"]
[44,"rs11882123",19,19552413,"rs4808955","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808955-?","rs4808955",0,4808955,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0401,"[0.023-0.057] unit decrease","Illumina [at least 560000] (imputed)","N"]
[44,"rs7245672",19,19692579,"rs7252981","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Perceived unattractiveness to mosquitoes","16,576 European ancestry individuals","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs7252981-T","rs7252981",0,7252981,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.112447,"[0.065-0.16] unit decrease","Illumina [7433384] (imputed)","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.12,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[45,"rs56113850",19,41370338,"rs12461383","2016-10-14",26634245,"Lutz SM","2015-12-03","BMC Genet","www.ncbi.nlm.nih.gov/pubmed/26634245","A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.","Post bronchodilator FEV1/FVC ratio","10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals","NA","19q13.2","Intergenic","AC008537.1",null,null,"ENSG00000268797",null,null,"rs12461383-C","rs12461383",0,12461383,"intron_variant",0,0.549,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.013,"unit increase","Illumina [NR] (imputed)","N"]
[46,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs566486324",19,45348253,"rs10426423","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","PVRL2","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,23575,1179,"rs10426423-C","rs10426423",0,10426423,"TF_binding_site_variant",1,0.620314,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.265674,"[1.15-1.38]","Affymetrix, Illumina [2928658] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2013-04-19",23326517,"Holliday EG","2013-01-11","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23326517","Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.","Age-related macular degeneration","3,772 European ancestry cases, 16,033 European ancestry controls","264 Asian ancestry cases, 3,926 Asian ancestry controls","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.86,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.21,"[1.11 - 1.32]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[46,"rs2238681",19,45403412,"rs1160985","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","LDL cholesterol levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs1160985-?","rs1160985",0,1160985,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.16,"[0.095-0.225] unit decrease","Illumina [1294241]","N"]
[46,"rs2238681",19,45403412,"rs1160985","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid AB1-42 levels","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","Intergenic","TOMM40",{"$nulls":5},"rs1160985-?","rs1160985",0,1160985,"intron_variant",0,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,131.1304,"[NR] unit decrease","Illumina [575353]","N"]
[46,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,0.536,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",0.018,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.897,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206462,"rs681343","2017-05-12",27992413,"Ji SG","2016-12-19","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27992413","Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.","Primary sclerosing cholangitis","2,871 European ancestry cases, 12,019 European ancestry controls","1,925 European ancestry cases, 7,936 European ancestry controls","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs681343-T","rs681343",0,681343,"stop_gained",0,0.46,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.11,"[1.06-1.17]","Affymetrix, Illumina [7891602] (imputed)","N"]
[51,"rs2179372",20,39724338,"rs6065311","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","20q12","MAFB","TOP1",null,null,"ENSG00000198900",null,null,"rs6065311-T","rs6065311",0,6065311,"intron_variant",0,0.194,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Asian initial, BMI unadjusted)",0.0485,"[0.028-0.069] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[51,"rs2179372",20,39724338,"rs6065311","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6065311-T","rs6065311",0,6065311,"intron_variant",0,0.194,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Asian initial, BMI unadjusted)",0.0485,"[0.028-0.069] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[3,"rs12067569",1,55529187,"rs505151","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs505151-A","rs505151",0,505151,"missense_variant",0,0.94,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(BMI unadjusted)",0.102,"[0.059-0.145] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Crohn's disease","12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls","NA","1p31.3","ANGPTL3, AL138847.1, DOCK7, USP1","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-?","rs1748195",0,1748195,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [9560910] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.19,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(chol, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum total protein level","Up to 25,539 European ancestry individuals, 10,168 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.56,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Japanese)",0.031,"[0.017-0.045] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[13,"rs4555772",5,74302658,"rs4555772","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Stearic acid (18:0) levels","8,961 European ancestry individuals",null,"5q13.3","GCNT4","AC116337.3, AC093259.1",null,null,"ENSG00000249856, ENSG00000249157",null,null,"rs4555772-A","rs4555772",0,4555772,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0888,"unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[13,"rs4704210",5,74605220,"rs10056811","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","5q13.3","intergenic","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,72517,10760,"rs10056811-A","rs10056811",0,10056811,"intergenic_variant",1,0.3466,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0274,"[0.016-0.039] unit increase","NR [8041861] (imputed)","N"]
[13,"rs888789",5,74988369,"rs888789","2014-11-27",24861553,"Wen W","2014-05-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/24861553","Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.","Body mass index","82,438 East Asian ancestry individuals, 4,301 South East Asian ancestry individuals","Up to 47,352 East Asian ancestry individuals","5q13.3","FLJ35779","POC5",null,null,"ENSG00000152359",null,null,"rs888789-A","rs888789",0,888789,"intron_variant",0,0.46,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.024,"[0.014-0.034] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[13,"rs253412",5,75015242,"rs2112347","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.629,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA, women)",0.0228,"[0.013-0.033] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[18,"rs641990",6,160791370,"rs3127574","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index","up to 309,889 European ancestry individuals","NA","6q25.3","SLC22A3, MAS1, AIRN, IGF2R, SLC22A1, SLC22A2, LPAL2, LPA, PLG, LOC729603","SLC22A3",null,null,"ENSG00000146477",null,null,"rs3127574-C","rs3127574",0,3127574,"intron_variant",0,0.51,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[21,"rs11250098",8,10818607,"rs11250098","2016-12-08",26835600,"Hu Y","2016-02-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26835600","GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.","Morning vs. evening chronotype","38,937 European ancestry morning chronotype individuals, 50,346 European ancestry evening chronotype individuals","NA","8p23.1","NR","XKR6",null,null,"ENSG00000171044",null,null,"rs11250098-?","rs11250098",0,11250098,"intron_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [7427422] (imputed)","N"]
[21,"rs2409784",8,11433909,"rs2898290","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.26,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[26,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,0.817,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[27,"rs115478735",9,136155000,"rs635634","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Stroke","40,585 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,154 African American controls, 365 Asian ancestry cases, 333 Asian ancestry controls, 865 Latin American cases, 692 Latin American controls","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47781306,"rs7927771","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","11p11.2","NR","FNBP4",null,null,"ENSG00000109920",null,null,"rs7927771-A","rs7927771",0,7927771,"intron_variant",0,0.6579,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0129,"[0.0074-0.0184] unit decrease","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,0.477,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174570",11,61597212,"rs174570","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","11q12.2","FADS2, FADS3","FADS2",null,null,"ENSG00000134824",null,null,"rs174570-G","rs174570",0,174570,"intron_variant",0,0.83,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.06,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[30,"rs174575",11,61602003,"rs174575","2015-08-09",25646338,"Mozaffarian D","2014-12-10","Am J Clin Nutr","www.ncbi.nlm.nih.gov/pubmed/25646338","Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.","Trans fatty acid levels","8,013 European ancestry individuals","1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174575-C","rs174575",0,174575,"intron_variant",0,0.7453,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Cis/trans-18:2, EA)",0.0021,"[0.0011-0.0031] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs2072114",11,61604967,"rs2072113","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs2072113-C","rs2072113",0,2072113,"intron_variant",0,0.872052617,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,1.1081095,"[1.06-1.16]","Illumina [10439017] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.778,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Asian initial, BMI unadjusted)",0.0449,"[0.026-0.064] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","Metabolic syndrome","1,811 Taiwanese Han Chinese ancestry cases, 8,489 Taiwanese Han Chinese ancestry controls","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(additive)",1.25,"[1.14-1.37]","Affymetrix [583469]","N"]
[31,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.023,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (large artery atherosclerosis)","4,373 European ancestry cases, 406,111 European ancestry controls, 1,626 East Asian ancestry cases, 28,195 East Asian ancestry controls, 355 South Asian ancestry cases, 6,707 South Asian ancestry controls, 259 African American cases, 15,146 African American controls, 34 Asian ancestry cases, 333 Asian ancestry controls, 41 Latin American cases, 692 Latin American controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Latino)",0.609,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.259,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[33,"rs35350651",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Latino)",0.613,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[37,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.33,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.628,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.104,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.52,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs9951682",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,0.675,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.31,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.308,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs58542926",19,19721722,"rs12610185","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs12610185-A","rs12610185",0,12610185,"intron_variant",0,0.053,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(TG )",0.03,"[NR] mg/dL increase","Illumina [899892]","N"]
[45,"rs56113850",19,41353107,"rs56113850","2017-03-31",27702941,"Cornelis MC","2016-10-03","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/27702941","Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.","Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level)","8,911 European ancestry individuals","824 European ancestry individuals","19q13.2","CYP2A6, NUMBL, ADCK4, ITPKC, SNRPA, MIA","CYP2A6, AC008537.1",null,null,"ENSG00000255974, ENSG00000268797",null,null,"rs56113850-T","rs56113850",0,56113850,"intron_variant",0,0.43,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,4.59,"Z-score increase","Illumina [~ 31000000] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.13,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.04,"[0.02-0.06] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[46,"rs1065853",19,45415640,"rs445925","2011-10-07",21909108,"Bis JC","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909108","Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.","Carotid intima media thickness","Up to 31,211 European ancestry individuals","10,553 European ancestry individuals, 687 Orcadian individuals","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-G","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.89,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(plaque)",1.22,"[1.12-1.32]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[51,"rs2179372",20,39678289,"rs6016505","2017-06-27",28560309,"Lee E","2017-04-23","Alzheimers Dement (Amst)","www.ncbi.nlm.nih.gov/pubmed/28560309","Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.","Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction)","242 European ancestry individuals","NA","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6016505-?","rs6016505",0,6016505,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [5908215] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(mass)",5.3E-3,"[-0.00215-0.01275] ng/ml decrease","Illumina [796174]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.012,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Urate levels","8,868 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.57,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.069,"[0.040,0.098] unit increase","Illumina [561583]","N"]
[9,"rs1260326",2,27742603,"rs780093","2012-08-20",22747683,"Eriksson N","2012-06-30","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/22747683","Genetic variants associated with breast size also influence breast cancer risk.","Breast size","16,175 European ancestry female individuals","NA","2p23.3","SLC4A1AP","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.416,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.072,"[0.041-0.103] cup size increase","Illumina [7422970] (imputed)","N"]
[16,"rs1233489",6,28482917,"rs13191038","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Urinary tract infection frequency","35,000 European ancestry cases, 33,478 European ancestry controls","NA","6p22.1","NR","GPX6, GPX6",null,null,"ENSG00000281185, ENSG00000198704",null,null,"rs13191038-?","rs13191038",0,13191038,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.058,"[0.033-0.083] unit increase","Illumina [at least 560000] (imputed)","N"]
[22,"rs287",8,19865175,"rs2083637","2008-06-22",18454146,"Chambers JC","2008-05-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18454146","Common genetic variation near MC4R is associated with waist circumference and insulin resistance.","Waist circumference and related phenotypes","2,684 Indian Asian ancestry male individuals","7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,40405,71450,"rs2083637-?","rs2083637",0,2083637,"regulatory_region_variant",1,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(HDL cholesterol)",null,null,"Illumina [308067]","N"]
[26,"rs4149307",9,107589580,"rs4149309","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149309-A","rs4149309",0,4149309,"intron_variant",0,0.8413,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.0418,"[0.024-0.06] unit decrease","NR [8041861] (imputed)","N"]
[26,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA, women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[26,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.4016,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(men)",0.0276,"[0.016-0.039] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,4.581,"[NR] Z score increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","11q23.3","ZNF259, APOA5, APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.163,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.05,"[1.03-1.08]","Affymetrix [9149595] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.191,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(South Asian)",0.333,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs545274",11,116829653,"rs7120173","2012-08-17",22589738,"Fox CS","2012-05-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22589738","Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.","Visceral adipose tissue adjusted for BMI","5,560 European ancestry female individuals, 4,997 European ancestry male individuals","NA","11q23.3","KIAA0999","SIK3",null,null,"ENSG00000160584",null,null,"rs7120173-G","rs7120173",0,7120173,"intron_variant",0,0.22,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(men)",null,null,"Affymetrix, Illumina [2500000] (imputed)","N"]
[33,"rs35350651",12,112059557,"rs11065979","2017-02-03",27197191,"Fehringer G","2016-04-20","Cancer Res","www.ncbi.nlm.nih.gov/pubmed/27197191","Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.","Cancer (pleiotropy)","5,020 European ancestry lung cancer cases, 3,718 European ancestry lung adenocarcinoma cases, 3,422 European ancestry lung squamous cell carcinoma cases, 15,414 European ancestry colorectal cancer cases, 10,809 European ancestry breast cancer cases, 4,939 European ancestry estrogen receptor negative breast cancer cases, 1,098 European ancestry ovarian cancer cases, 2,556 European ancestry serous ovarian cancer cases, 715 European ancestry ovarian endometrioid carcinoma cases, 9,710 European ancestry prostate cancer cases, 4,450 European ancestry aggressive prostate cancer cases,  61,820 European ancestry controls","NA","12q24.12","Intergenic","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(subset analysis)",null,null,"Affymetrix, Illumina [9916564] (imputed)","N"]
[33,"rs35350651",12,112684221,"rs7953257","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma-induced protein 10 levels","3,685 Finnish ancestry individuals","NA","12q24.13","NR","HECTD4",null,null,"ENSG00000173064",null,null,"rs7953257-T","rs7953257",0,7953257,"intron_variant",0,null,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.1088,"[0.062-0.156] SD units decrease","NR [10700000] (imputed)","N"]
[37,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.596,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.02,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.914,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.027,"[0.015-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[46,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,0.923,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs1985129",19,45382717,"rs406456","2019-02-21",30498476,"Liu H","2018-11-15","Front Endocrinol (Lausanne)","www.ncbi.nlm.nih.gov/pubmed/30498476","Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.","Low density lipoprotein cholesterol levels","139 Chinese ancestry dizygotic twin pairs","NA","19q13.32","NECTIN2","NECTIN2",null,null,"ENSG00000130202",null,null,"rs406456-?","rs406456",0,406456,"intron_variant",0,null,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,{"$nulls":3},"Illumina [7405822] (imputed)","N"]
[46,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.883,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","19q13.32","APOC2, APOE, APOC4, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.21,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(TG)",0.22,"[NR] mg/dL increase","Affymetrix [408775]","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.883,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs8111874",19,49206172,"rs516246","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Inflammatory bowel disease","25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls","NA","19q13.33","IZUMO1, NTN5, FUT2, MAMSTR, RASIP1","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-?","rs516246",0,516246,"intron_variant",0,null,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,{"$nulls":3},"Illumina [9725440] (imputed)","N"]
[47,"rs8111874",19,49206462,"rs681343","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung adenocarcinoma","11,273 European ancestry cases,  55,483 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs681343-T","rs681343",0,681343,"stop_gained",0,0.526442405,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.0764673,"[1.04-1.11]","Illumina [10439017] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.065,"[0.038-0.092] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.59,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.05,"[0.028-0.072] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[13,"rs4704187",5,74480288,"rs4704187","2012-11-05",22952603,"Hart AB","2012-08-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/22952603","Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).","Response to amphetamines","1 American Indian ancestry individual, 18 African American individuals, 10 Asian ancestry individuals, 325 European ancestry individuals, 17 Hispanic individuals, 10 individuals","NA","5q13.3","ANKRD31","ANKRD31",null,null,"ENSG00000145700",null,null,"rs4704187-?","rs4704187",0,4704187,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(SF6)",null,null,"Affymetrix [5476100] (imputed)","N"]
[13,"rs4704210",5,74655726,"rs3846663","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","5q13.3","COL4A3BP, HMGCR","COL4A3BP, HMGCR",null,null,"ENSG00000113163, ENSG00000113161",null,null,"rs3846663-T","rs3846663",0,3846663,"intron_variant",0,0.39,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(TC)",0.19,"[NR] mg/dL increase","Affymetrix [408775]","N"]
[13,"rs4704210",5,74934009,"rs34341","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","5q13.3","COL4A3BP, POLK","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs34341-A","rs34341",0,34341,"intron_variant",0,0.438944,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(females)",0.01588,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[13,"rs56912706",5,75034387,"rs7715806","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,21081,14008,"rs7715806-C","rs7715806",0,7715806,"intergenic_variant",1,0.6006,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.0244,"[0.014-0.035] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[17,"rs114863007",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.844,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA, women)",0.0278,"[0.016-0.04] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[26,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI in non-smokers","77,279 European ancestry women, 47,280 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men","16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.0245,"[0.014-0.035] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[30,"rs174564",11,61543961,"rs174529","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","TMEM258, MYRF",null,null,"ENSG00000134825, ENSG00000124920",null,null,"rs174529-T","rs174529",0,174529,"intron_variant",0,0.374,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(East Asian)",0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs10892019",11,116599392,"rs180358","2009-01-16",19010793,"Baranzini SE","2008-11-14","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/19010793","Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.","Multiple sclerosis (severity)","794 European ancestry cases, 883 European ancestry controls","NA","11q23.3","MGC13125","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,70424,19494,"rs180358-?","rs180358",0,180358,"intergenic_variant",1,0.23,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,null,"[NR]","Illumina [551642]","N"]
[33,"rs35350651",12,111884608,"rs3184504","2010-06-13",20453842,"Stahl EA","2010-05-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20453842","Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.","Rheumatoid arthritis","5,539 European ancestry cases, 20,169 European ancestry controls","6,768 European ancestry cases, 8,806 European ancestry controls","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.51,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.08,"[NR]","Affymetrix, Illumina [~ 2716259] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2011-04-11",21378990,"Schunkert H","2011-03-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21378990","Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.","Coronary heart disease","22,233 European ancestry cases, 64,762 European ancestry controls","56,682 European ancestry cases and controls","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.44,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.07,"[1.04-1.10]","Affymetrix, Illumina [~ 2300000] (imputed)","N"]
[33,"rs35350651",12,111884608,"rs3184504","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (small-vessel)","5,386 European ancestry cases, 192,662 European ancestry controls, 5,096 East Asian ancestry cases, 28,195 East Asian ancestry controls, 314 South Asian ancestry cases, 6,707 South Asian ancestry controls, 694 African American cases, 15,146 African American controls, 134 Asian ancestry cases, 333 Asian ancestry controls, 86 Latin American cases, 692 Latin American controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[33,"rs35350651",12,112591686,"rs17630235","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.13","NR","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-G","rs17630235",0,17630235,"intergenic_variant",1,null,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Latino)",0.613,"unit decrease","Affymetrix [at least 2696785] (imputed)","N"]
[34,"rs7970695",12,121403724,"rs7953249","2017-08-03",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Invasive epithelial ovarian cancer","22,406 European ancestry cases, 40,941 European ancestry controls","NA","12q24.31","NR","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.417632,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.0621586,"[1.0348111352015-1.09022867520121]","Illumina [11595112] (imputed)","N"]
[38,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.794,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Hispanic)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs113954889",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Systolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.34,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Japanese)",0.3725,"[0.21-0.53] unit increase","Illumina [6200000] (imputed)","N"]
[46,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45395619,"rs2075650","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.8558,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.0234,"[0.013-0.034] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[46,"rs157595",19,45425460,"rs157595","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19q13.32","APOC1, APOC1P1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-A","rs157595",0,157595,"intergenic_variant",1,0.397,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.032,"[0.018-0.046] unit decrease","Affymetrix [7947838] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.078,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.134,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2010-09-21",20705733,"O'Seaghdha CM","2010-08-12","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20705733","Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.","Calcium levels","20,611 European ancestry individuals","NA","2p23.3","FNDC4, IFT172, GCKR, C2orf16","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs74175068",2,27801759,"rs1919128","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919128-G","rs1919128",0,1919128,"missense_variant",0,0.529,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0379,"[0.021-0.054] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[16,"rs1233489",6,28796071,"rs3131337","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Cold sores","25,108 European ancestry cases, 63,332 European ancestry controls","NA","6p22.1","NR","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,44290,9575,"rs3131337-?","rs3131337",0,3131337,"regulatory_region_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0811,"[0.046-0.116] unit decrease","Illumina [at least 560000] (imputed)","N"]
[16,"rs1233489",6,28916594,"rs3130844","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Urinary tract infection frequency","35,000 European ancestry cases, 33,478 European ancestry controls","NA","6p22.1","NR","LINC01556 - KRT18P1","ENSG00000231041","ENSG00000226462",null,4280,20313,"rs3130844-?","rs3130844",0,3130844,"regulatory_region_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0564,"[0.032-0.081] unit increase","Illumina [at least 560000] (imputed)","N"]
[18,"rs10945649",6,160402705,"rs6917747","2009-01-16",19010793,"Baranzini SE","2008-11-14","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/19010793","Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.","Brain lesion load","791 European ancestry cases, 883 European ancestry controls","NA","6q25.3","IGF2R","IGF2R",null,null,"ENSG00000197081",null,null,"rs6917747-?","rs6917747",0,6917747,"intron_variant",0,0.15,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,null,"[NR]","Illumina [551642]","N"]
[18,"rs10455872",6,161108144,"rs2315065","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (combined parental age at death)","45,627 middle-aged British individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,10589,11176,"rs2315065-?","rs2315065",0,2315065,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.056891,"[0.032-0.082] unit increase","Affymetrix [9658292] (imputed)","N"]
[20,"rs2976940",8,8304502,"rs2921077","2018-07-16",29739929,"Visconti A","2018-05-08","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29739929","Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.","Non-melanoma skin cancer","5,912 European ancestry cases, 181,740 European ancestry controls",null,"8p23.1","NR","AC103957.1 - AC103957.2","ENSG00000253505","ENSG00000254153",null,22352,9917,"rs2921077-G","rs2921077",0,2921077,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,1.0887696,"[1.05-1.13]","Affymetrix [5734850] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.614,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954038",8,126507389,"rs2954038","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","8q24.13","NSMCE2, KIAA0196, TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-C","rs2954038",0,2954038,"intron_variant",0,0.32,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Triglyceride, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[29,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(men)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61571478,"rs174550","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2, FADS1",null,null,"ENSG00000134824, ENSG00000149485",null,null,"rs174550-T","rs174550",0,174550,"5_prime_UTR_variant",0,0.379,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61573684,"rs174551","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174551-T","rs174551",0,174551,"5_prime_UTR_variant",0,0.454,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61579463,"rs174554","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174554-A","rs174554",0,174554,"intron_variant",0,0.379,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs174564",11,61597972,"rs1535","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","11q12.2","FEN, FADS1, FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs1535-G","rs1535",0,1535,"intron_variant",0,0.32,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(HDL, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[30,"rs174564",11,61604814,"rs174577","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,0.374,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs473172",11,116921397,"rs1815787","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs1815787-T","rs1815787",0,1815787,"intron_variant",0,0.1173,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.020935446,"[0.012-0.03] unit increase","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[33,"rs35350651",12,111833788,"rs10774624","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma-induced protein 10 levels","3,685 Finnish ancestry individuals","NA","12q24.12","NR","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-G","rs10774624",0,10774624,"intron_variant",0,null,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.1069,"[0.06-0.154] SD units increase","NR [10700000] (imputed)","N"]
[37,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.376,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.057,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.815,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs9951682",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1883711",20,39142516,"rs2207132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,387519,171972,"rs2207132-G","rs2207132",0,2207132,"intergenic_variant",1,0.963,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1883711",20,39142516,"rs2207132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,387519,171972,"rs2207132-G","rs2207132",0,2207132,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63118196,"rs10889353","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.32,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.06,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[8,"rs668948",2,21294975,"rs541041","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","2p24.1","FLJ21820, GDF7, APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.16,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(LDL, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[20,"rs1461729",8,9184231,"rs4240624","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-G","rs4240624",0,4240624,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.0869565,"[NR]","Illumina [7158791] (imputed)","N"]
[20,"rs4240623",8,9186524,"rs4841134","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841134-?","rs4841134",0,4841134,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,{"$nulls":3},"Affymetrix [NR]","N"]
[21,"rs7005363",8,10283426,"rs3750310","2018-06-29",28714469,"Langefeld CD","2017-07-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28714469","Transancestral mapping and genetic load in systemic lupus erythematosus.","Systemic lupus erythematosus","6,748 European ancestry cases, 11,516 European ancestry controls, 2,970 African American cases, 2,452 African American controls, 1,872 Hispanic cases, 2,016 Hispanic controls","NA","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs3750310-G","rs3750310",0,3750310,"intron_variant",0,0.692,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(Hispanic)",1.28,"[1.15-1.42]","Illumina [at least 5000000] (imputed)","N"]
[21,"rs11250098",8,11039816,"rs2409722","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Positive affect","180,281 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","8p23.1","NR","XKR6",null,null,"ENSG00000171044",null,null,"rs2409722-T","rs2409722",0,2409722,"intron_variant",0,0.488,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.0149,"[0.0084-0.0214] unit increase","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[22,"rs11986942",8,19824492,"rs13702","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs13702-T","rs13702",0,13702,"3_prime_UTR_variant",0,0.501,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(AA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11986942",8,19824667,"rs15285","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p21.3","NR","LPL",null,null,"ENSG00000175445",null,null,"rs15285-C","rs15285",0,15285,"3_prime_UTR_variant",0,0.505,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(AA)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.502,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs112875651",8,126506694,"rs112875651","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8q24.13","TRIB1, LOC100130231","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.11,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[26,"rs4149307",9,107591272,"rs7031748","2013-01-16",23049088,"Meng W","2012-10-09","Invest Ophthalmol Vis Sci","www.ncbi.nlm.nih.gov/pubmed/23049088","A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.","Myopia (pathological)","187 European ancestry cases, 1064 European ancestry controls",null,"9q31.1","intergenic","ABCA1",null,null,"ENSG00000165029",null,null,"rs7031748-?","rs7031748",1,2853579,"synonymous_variant",0,0.134,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,null,"[NR]","Affymetrix, Illumina [152234]","N"]
[26,"rs13284054",9,107657070,"rs3905000","2017-08-07",27082954,"Ward-Caviness CK","2016-04-15","PLoS One","www.ncbi.nlm.nih.gov/pubmed/27082954","Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease.","Peripheral arterial disease (traffic-related air pollution interaction)","104 European ancestry cases, 1,519 European ancestry controls, 34 African American cases, 520 African American controls","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-?","rs3905000",0,3905000,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(AA)",5,"[4.14-5.86]","Illumina [905956]","N"]
[30,"rs174564",11,61604814,"rs174577","2017-10-24",28898252,"Wheeler E","2017-09-12","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/28898252","Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.","Glycated hemoglobin levels","88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals","33,238 European ancestry individuals,  2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals","11q12.2","FADS2","FADS2",null,null,"ENSG00000134824",null,null,"rs174577-C","rs174577",0,174577,"intron_variant",0,0.5111,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.0177,"[0.0099-0.0255] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs2727263",11,61616012,"rs2851682","2017-02-27",27490719,"Bacelis J","2016-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/27490719","Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways.","Gestational age at birth (child effect)","1,109 Norwegian ancestry children","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs2851682-G","rs2851682",0,2851682,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,{"$nulls":3},"NR [525577]","N"]
[31,"rs35120633",11,116613660,"rs12280753","2010-09-28",20838585,"Smith EN","2010-09-09","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20838585","Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.","Cardiovascular risk factors (age interaction)","525 European ancestry individuals","2,442 Finnish ancestry individuals","11q23.3","CADM1, APOA5, BUD13","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,84692,5226,"rs12280753-T","rs12280753",0,12280753,"regulatory_region_variant",1,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(triglycerides)",0.69,"[0.40-0.98] unit increase","Illumina [2173391] (imputed)","N"]
[33,"rs35350651",12,111904371,"rs4766578","2018-04-25",24097067,"Lessard CJ","2013-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097067","Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.","Sjögren's syndrome","1,541 European ancestry cases, 2,634 European ancestry controls","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-T","rs4766578",0,4766578,"intron_variant",0,0.48,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.23,"[1.12-1.35]","Illumina [102585]","N"]
[37,"rs261290",15,58683366,"rs1532085","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.403,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(Filipino)",1.634,"[1.56-1.70] unit decrease","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[37,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.358,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[43,"rs56322906",19,11330942,"rs17699030","2012-11-02",20889312,"Wang KS","2010-10-01","Schizophr Res","www.ncbi.nlm.nih.gov/pubmed/20889312","A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.","Bipolar disorder and schizophrenia","651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs17699030-?","rs17699030",0,17699030,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7062,"[NR]","Affymetrix [722112]","N"]
[44,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[46,"rs11556505",19,45392254,"rs6857","2016-04-28",26154020,"Ferrari R","2015-06-12","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/26154020","A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.","Frontotemporal dementia","530 European ancestry cases, 926 European ancestry controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.13,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7,"[1.46-1.94]","Illumina [2292247] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-05-11",29436472,"Casalone E","2018-02-07","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/29436472","A novel variant in GLIS3 is associated with osteoarthritis.","Osteoarthritis of the knee (with total joint replacement)","2,188 European ancestry cases, 9,939 European ancestry healthy controls","2,281 European ancestry cases, 9,194 European ancestry healthy controls","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.017137,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,1.56,"[1.25-1.95]","Illumina [270934]","N"]
[4,"1:62980399_CACA_C",1,62912919,"rs10158897","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","1p31.3","USP1","USP1",null,null,"ENSG00000162607",null,null,"rs10158897-T","rs10158897",0,10158897,"intron_variant",0,0.2,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(LDL)",0.021,"mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.021,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs67798437",2,27801418,"rs1919126","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919126-C","rs1919126",0,1919126,"missense_variant",0,null,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.20432469,"[0.11-0.29] unit decrease","Illumina [247039]","N"]
[10,"rs11887534",2,44066247,"rs11887534","2019-03-21",30325047,"Gellert-Kristensen H","2018-10-16","Hepatology","www.ncbi.nlm.nih.gov/pubmed/30325047","Identification and replication of six new loci associated with gallstone disease.","Gallstone disease","14,940 British ancestry cases, 322,268 British ancestry controls","1,522 Danish ancestry cases, 18,266 Danish ancestry controls","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-C","rs11887534",0,11887534,"missense_variant",0,0.07,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,2.01,"[1.94-2.08]","Affymetrix [784257]","N"]
[20,"rs1461729",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs7816447",8,19844222,"rs12678919","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","8p21.3","LPL","LPL - AC100802.1","ENSG00000175445","ENSG00000253775",null,19452,92403,"rs12678919-G","rs12678919",0,12678919,"intergenic_variant",1,0.18,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(HDL)",0.125,"[0.070-0.180] unit increase","Illumina [561583]","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs4149307",9,107588777,"rs4149311","2013-01-16",23049088,"Meng W","2012-10-09","Invest Ophthalmol Vis Sci","www.ncbi.nlm.nih.gov/pubmed/23049088","A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.","Myopia (pathological)","187 European ancestry cases, 1064 European ancestry controls",null,"9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149311-?","rs4149311",0,4149311,"intron_variant",0,0.134,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,null,"[NR]","Affymetrix, Illumina [152234]","N"]
[26,"rs13284054",9,107657070,"rs3905000","2016-03-24",21116278,"Furney SJ","2010-11-30","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/21116278","Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.","Whole-brain volume (Alzheimer's disease interaction)","434 European ancestry mild cognitive impairment cases, 245 European ancestry Alzheimer's disease cases, 284 European ancestry controls","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-?","rs3905000",0,3905000,"intron_variant",0,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.013,"[NR] unit increase","Illumina [478011]","N"]
[30,"rs174564",11,61609750,"rs174583","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q12.2","NR","FADS2",null,null,"ENSG00000134824",null,null,"rs174583-C","rs174583",0,174583,"intron_variant",0,0.477,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(Hispanic)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs651821",11,116647607,"rs2160669","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs2160669-G","rs2160669",0,2160669,"3_prime_UTR_variant",0,0.168,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(TG/HDLC )",0.03,"[NR] mmol/L increase","Illumina [899892]","N"]
[31,"rs651821",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.115,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(Hispanic)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"rs35350651",12,111833788,"rs10774624","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Monokine induced by gamma interferon levels","3,685 Finnish ancestry individuals","NA","12q24.12","NR","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-G","rs10774624",0,10774624,"intron_variant",0,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.1056,"[0.059-0.152] SD units increase","NR [10700000] (imputed)","N"]
[33,"rs35350651",12,112817521,"rs10850034","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma-induced protein 10 levels","3,685 Finnish ancestry individuals","NA","12q24.13","NR","HECTD4",null,null,"ENSG00000173064",null,null,"rs10850034-T","rs10850034",0,10850034,"intron_variant",0,null,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.1055,"[0.059-0.152] SD units decrease","NR [10700000] (imputed)","N"]
[38,"rs289713",16,57006590,"rs7499892","2009-03-31",19260141,"Zemunik T","2009-02-01","Croat Med J","www.ncbi.nlm.nih.gov/pubmed/19260141","Genome-wide association study of biochemical traits in Korcula Island, Croatia.","Biochemical measures","898 Korculan (founder/genetic isolate) individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-A","rs7499892",0,7499892,"intron_variant",0,0.16,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(HDL cholesterol)",0.24,"[0.14-0.34] mmol/L decrease","Illumina [316730]","N"]
[46,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,0.964,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs2378390",20,34125271,"rs6579245","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q11.22","NR","C20orf173 - ERGIC3","ENSG00000125975","ENSG00000125991",null,7795,4574,"rs6579245-C","rs6579245",0,6579245,"intergenic_variant",1,0.85,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[34,"rs7970695",12,121423659,"rs9738226","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs9738226-A","rs9738226",0,9738226,"intron_variant",0,0.39,"1E-313",313,"(BMI-adjusted)",0.148,"[0.14-0.16] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[10,"rs11887534",2,44066247,"rs11887534","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-?","rs11887534",0,11887534,"missense_variant",0,null,"1E-353",353,null,1.94,"[1.88-2.08]","Affymetrix, Illumina [43000000] (imputed)","N"]
[18,"rs10455872",6,160985526,"rs118039278","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs118039278-A","rs118039278",0,118039278,"intron_variant",0,null,"1E-396",396,null,32.43,"[31.14-33.72] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[31,"rs964184",11,116648917,"rs964184","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8418,"1E-500",500,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[38,"rs247617",16,56985514,"rs72786786","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6739,10248,"rs72786786-A","rs72786786",0,72786786,"regulatory_region_variant",1,0.3106,"1E-500",500,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[46,"rs41290120",19,45382675,"rs41290120","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs41290120-A","rs41290120",0,41290120,"intron_variant",0,0.0416,"1E-500",500,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[31,"rs651821",11,116662579,"rs651821","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-?","rs651821",0,651821,"5_prime_UTR_variant",0,"NR","1E-537",537,null,0.2208,"[0.21-0.23] unit decrease novel","Illumina [6108953] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,"1E-769",769,null,0.241,"[NR] unit increase","NR [NR] (imputed)","N"]
[30,"rs174564",11,61571348,"rs174548","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","11q12.2","FADS1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174548-C","rs174548",0,174548,"5_prime_UTR_variant",0,0.7,"2E-361",360.698970004336,"(arachidonate (20:4n6)/dihomo-linolenate (20:3n3 or n6))",0.071,"[0.067-0.075] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,"3E-418",417.52287874528,"(Leucine-rich repeat neuronal protein 1, LRRN1.11293.14.3)",1.18,"[1.12-1.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,"3E-484",483.52287874528,"(Vacuolar protein sorting-associated protein 29, VPS29.14318.1.3)",1.69,"[1.61-1.77] unit increase","Affymetrix [10572788] (imputed)","N"]
[30,"rs174564",11,61570783,"rs174547","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)","8,631 European ancestry individuals","NA","11q12.2","FTH1, INCENP, FADS1, FADS2, SCGB2A1, SCGB1D1, SCGB2A2, RAB3IL1, AHNAK, C11orf9, DAGLA, FEN1, FADS3, SYT7, BEST1","FADS1, FADS2",null,null,"ENSG00000149485, ENSG00000134824",null,null,"rs174547-C","rs174547",0,174547,"intron_variant",0,0.33,"3E-971",970.52287874528,null,1.69,"[1.65-1.73] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[31,"rs651821",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.92,"4E-315",314.397940008672,"(Trans-ethnic initial)",0.247,"[0.23-0.26] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,"4E-328",327.397940008672,null,0.247,"[0.24-0.26] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[46,"rs1065853",19,45413233,"rs1065853","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-G","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.93,"5E-324",323.301029995663,null,0.603,"[0.58-0.63] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,"5E-646",645.301029995664,"(Tubulin-specific chaperone A, TBCA.12501.10.3)",1.34,"[1.3-1.38] unit decrease","Affymetrix [10572788] (imputed)","N"]
[46,"rs429358",19,45411941,"rs429358","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,"6E-363",362.221848749616,"(BMI-adjusted)",0.24,"[0.23-0.25] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[38,"rs247617",16,56994528,"rs17231506","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-T","rs17231506",0,17231506,"regulatory_region_variant",1,0.31,"7E-316",315.154901959985,null,0.243,"[0.23-0.25] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[46,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,"7E-370",369.154901959985,"(Valine--tRNA ligase, VARS.13083.18.3)",0.87,"[0.83-0.91] unit increase","Affymetrix [10572788] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,"7E-380",379.154901959985,null,3.39,"[3.21-3.57] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[46,"rs1065853",19,45412079,"rs7412","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.066,"8E-315",314.096910013008,"(Trans-ethnic initial)",0.374,"[0.36-0.39] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[38,"rs247617",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.294,"9E-311",310.04575749056,"(Trans-ethnic initial)",0.241,"[0.23-0.25] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]

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["GenomicLocus","IndSigSNP","chr","bp","snp","DateAddedToCatalog","PMID","FirstAuth","Date","Journal","Link","Study","Trait","InitialN","ReplicationN","Region","ReportedGene","MappedGene","UpGene","DownGene","SNP_Gene_ID","UpGeneDist","DownGeneDist","Strongest","SNPs","marged","SNP_ID_cur","Context","intergenic","RiskAF","P","Pmlog","Ptext","OrBeta","95CI","Platform","CNV"]
[5,"rs3832016",1,109817192,"rs7528419","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7782,{"v":0,"d":"0.00E+00"},308.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[42,"rs3816117",16,56996211,"rs711752","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs711752-A","rs711752",0,711752,"splice_region_variant",0,"NR",{"v":4e-308,"d":"4.00E-308"},307.397940008672,{"$nulls":3},"NR [2501543] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":1E-305,"d":"1.00E-305"},305,null,0.229,"[0.22-0.24] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1e-302,"d":"1.00E-302"},302,"(BIRC2)",1.6999545,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs611917",1,109815252,"rs611917","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs611917-A","rs611917",0,611917,"non_coding_transcript_exon_variant",0,0.6818,{"v":1E-300,"d":"1.00E-300"},300,null,0.1122,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.7715,{"v":1E-300,"d":"1.00E-300"},300,null,0.1364,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.379,{"v":1E-300,"d":"1.00E-300"},300,null,0.1118,"[0.11-0.12] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116586283,"rs7350481","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-T","rs7350481",0,7350481,"regulatory_region_variant",1,0.0708,{"v":1E-300,"d":"1.00E-300"},300,null,0.2272,"[0.22-0.24] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.251,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.25,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.17,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs58065809",11,117002403,"rs6589598","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","PCSK7","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,12506,3841,"rs6589598-G","rs6589598",0,6589598,"intergenic_variant",1,0.778,{"v":1E-300,"d":"1.00E-300"},300,"(PCSK7)",1.043,"[1-1.09] unit increase","Illumina [> 1000000] (imputed)","N"]
[37,"rs4766578",12,111833788,"rs10774624","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","12q24.12",null,"LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-?","rs10774624",0,10774624,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.685,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.216,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.213,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.208,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.219,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.683,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.218,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.212,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.6902,{"v":1E-300,"d":"1.00E-300"},300,null,0.2211,"[0.22-0.23] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.716,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.214,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.218,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.685,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.212,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.215,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.822,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.217,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.207,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.564,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.821,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11187324,"rs143020224","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4",null,null,"ENSG00000127616",null,null,"rs143020224-C","rs143020224",0,143020224,"intron_variant",0,0.8693,{"v":1E-300,"d":"1.00E-300"},300,null,0.1619,"[0.15-0.17] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs41290120",19,45319631,"rs118147862","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","BCAM","BCAM",null,null,"ENSG00000187244",null,null,"rs118147862-A","rs118147862",0,118147862,"intron_variant",0,0.0369,{"v":1E-300,"d":"1.00E-300"},300,null,0.3977,"[0.38-0.41] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.493,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.498,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":1E-300,"d":"1.00E-300"},300,"(EA)",0.342,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-300,"d":"1.00E-300"},300,null,0.348,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","HERPUD1, CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-?","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":2e-300,"d":"2.00E-300"},299.698970004336,null,0.2656,"[0.25-0.28] unit increase novel","Illumina [6108953] (imputed)","N"]
[38,"rs7970695",12,121424861,"rs7310409","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.39,{"v":3e-299,"d":"3.00E-299"},298.52287874528,null,0.137,"[0.13-0.14] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-297,"d":"3.00E-297"},296.52287874528,null,0.14,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2010-06-14",20460622,"Seshadri S","2010-05-12","JAMA","www.ncbi.nlm.nih.gov/pubmed/20460622","Genome-wide analysis of genetic loci associated with Alzheimer disease.","Alzheimer's disease","973 incident AD cases, 2,033 prevalent AD cases, 22,604  controls of European and Hispanic ancestry","6,505 European ancestry cases, 13,532 European ancestry controls","19q13.32","APOE","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,0.14,{"v":1e-295,"d":"1.00E-295"},295,null,2.53,"[2.41-2.66]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[50,"rs75627662",19,45413576,"rs75627662","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Family history of Alzheimer's disease","47,793 European ancestry cases, 328,320 European ancestry controls","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-T","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-295,"d":"1.00E-295"},295,null,36.79,"NR z-score increase","Affymetrix [10847151] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":4E-289,"d":"4.00E-289"},288.397940008672,"(Trans-ethnic initial)",0.16,"[0.15-0.17] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":6e-289,"d":"6.00E-289"},288.221848749616,null,0.247,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":7E-287,"d":"7.00E-287"},286.154901959985,null,0.246,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19q13.32","APOC1, APOE, APOC2","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.066,{"v":2e-286,"d":"2.00E-286"},285.698970004336,"(Trans-ethnic initial)",0.59,"[0.57-0.61] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[19,"rs56393506",6,161089307,"rs56393506","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,null,{"v":8e-285,"d":"8.00E-285"},284.096910013008,null,13.6,"[12.78-14.42] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":6e-284,"d":"6.00E-284"},283.221848749616,null,0.239,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-283,"d":"1.00E-283"},283,{"$nulls":3},"NR [2501749] (imputed)","N"]
[48,"rs142158911",19,11196886,"rs8106503","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","intergenic","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,6784,3152,"rs8106503-T","rs8106503",0,8106503,"intergenic_variant",1,0.8354,{"v":2E-281,"d":"2.00E-281"},280.698970004336,null,0.1334,"[0.13-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-272,"d":"2.00E-272"},271.698970004336,"(EA)",0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7970695",12,121424861,"rs7310409","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-A","rs7310409",0,7310409,"intron_variant",0,0.39,{"v":8e-269,"d":"8.00E-269"},268.096910013008,null,0.147,"[0.14-0.15] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-268,"d":"5.00E-268"},267.301029995663,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,"NR",{"v":1e-266,"d":"1.00E-266"},266,null,0.122,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":4E-262,"d":"4.00E-262"},261.397940008672,null,0.221,"[NR] unit decrease","NR [NR] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3642,{"v":3e-259,"d":"3.00E-259"},258.52287874528,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0149,{"v":3e-257,"d":"3.00E-257"},256.52287874528,null,0.3952,"[0.37-0.42] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.413,{"v":4e-253,"d":"4.00E-253"},252.397940008672,"(Trans-ethnic initial)",0.115,"[0.11-0.12] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[48,"rs142158911",19,11191197,"rs114846969","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19p13.2","NR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,1095,8841,"rs114846969-A","rs114846969",0,114846969,"intergenic_variant",1,0.1172,{"v":2e-252,"d":"2.00E-252"},251.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-251,"d":"3.00E-251"},250.52287874528,"(EA)",0.141,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.393,{"v":4e-251,"d":"4.00E-251"},250.397940008672,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":3e-250,"d":"3.00E-250"},249.52287874528,"(EA)",0.169,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3E-249,"d":"3.00E-249"},248.52287874528,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",0.76,"[0.72-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":4e-249,"d":"4.00E-249"},248.397940008672,{"$nulls":3},"NR [2501549] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2E-247,"d":"2.00E-247"},246.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":2e-245,"d":"2.00E-245"},244.698970004336,null,0.183,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.798,{"v":8e-244,"d":"8.00E-244"},243.096910013008,"(ABO)",1.087,"[1.07-1.11] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-242,"d":"5.00E-242"},241.301029995663,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":7e-242,"d":"7.00E-242"},241.154901959985,null,0.18,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":5e-241,"d":"5.00E-241"},240.301029995663,null,0.167,"[NR] unit decrease","NR [NR] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":7e-240,"d":"7.00E-240"},239.154901959985,null,16.95,"[16.01-17.89] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-239,"d":"1.00E-239"},239,"(Centrosomal protein of 57 kDa, CEP57.11276.1.3)",1.33,"[1.25-1.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":2e-239,"d":"2.00E-239"},238.698970004336,null,0.115,"[NR] mg/dL increase","NR [NR] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93,{"v":8e-239,"d":"8.00E-239"},238.096910013008,null,0.413,"[0.39-0.44] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[48,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":1E-236,"d":"1.00E-236"},236,null,0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1081105",19,45412955,"rs1081105","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1081105-C","rs1081105",0,1081105,"non_coding_transcript_exon_variant",0,0.02756,{"v":1e-231,"d":"1.00E-231"},231,null,32.50298,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[19,"rs186696265",6,161111700,"rs186696265","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,null,{"v":4E-231,"d":"4.00E-231"},230.397940008672,null,64.74,"[62.11-67.37] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":1E-230,"d":"1.00E-230"},230,null,0.227,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-T","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.232,{"v":4e-230,"d":"4.00E-230"},229.397940008672,"(CUB and zona pellucida-like domain-containing protein 1, CUZD1.7943.16.3)",0.82,"[0.76-0.88] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.215441066,{"v":9e-230,"d":"9.00E-230"},229.04575749056,"(GRN)",0.727792,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[8,"rs668948",2,21299867,"rs577584","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,32922,46922,"rs577584-A","rs577584",0,577584,"intergenic_variant",1,0.6896,{"v":1e-229,"d":"1.00E-229"},229,null,0.1008,"[0.095-0.107] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-228,"d":"9.00E-228"},227.04575749056,null,0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-227,"d":"4.00E-227"},226.397940008672,null,0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":3E-226,"d":"3.00E-226"},225.52287874528,null,0.216,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":7e-224,"d":"7.00E-224"},223.154901959985,null,0.234,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":8e-222,"d":"8.00E-222"},221.096910013008,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-G","rs157580",0,157580,"intron_variant",0,0.3949,{"v":8e-220,"d":"8.00E-220"},219.096910013008,null,31.6502,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[35,"rs11820589",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":2e-219,"d":"2.00E-219"},218.698970004336,null,0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,"NR",{"v":3e-218,"d":"3.00E-218"},217.52287874528,null,0.274,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Plateletcrit","164,339 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5175,{"v":5e-216,"d":"5.00E-216"},215.301029995663,null,0.114319,"[0.11-0.12] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.367,{"v":1e-213,"d":"1.00E-213"},213,"(Trans-ethnic initial)",0.107,"[0.1-0.11] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.28,{"v":4e-213,"d":"4.00E-213"},212.397940008672,null,0.081,"[0.075-0.087] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[19,"rs55730499",6,161123451,"rs4252185","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","PLG",null,null,"ENSG00000122194",null,null,"rs4252185-C","rs4252185",0,4252185,"intron_variant",0,null,{"v":5e-211,"d":"5.00E-211"},210.301029995663,null,23.93,"[22.64-25.22] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":8e-211,"d":"8.00E-211"},210.096910013008,"(Granulins, GRN.4992.49.1)",0.83,"[0.77-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-210,"d":"4.00E-210"},209.397940008672,"(UBA2)",1.4728388,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":2e-208,"d":"2.00E-208"},207.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[19,"rs186696265",6,161111700,"rs186696265","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,null,{"v":2e-207,"d":"2.00E-207"},206.698970004336,null,49.06,"[46.85-51.27] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[48,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":1E-206,"d":"1.00E-206"},206,"(EA)",0.222,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":5E-205,"d":"5.00E-205"},204.301029995663,"(Protein CEI, C5orf38.6378.2.3)",1.25,"[1.17-1.33] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.782,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(Trans-ethnic initial)",0.128,"[0.12-0.14] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2E-204,"d":"2.00E-204"},203.698970004336,"(EA)",0.22,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.179,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-202,"d":"2.00E-202"},201.698970004336,"(EA)",0.228,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18272535,"rs35246381","2016-09-07",26352407,"Raffler J","2015-09-09","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26352407","Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality.","Urinary metabolites","3,861 European ancestry individuals","1,691European ancestry individuals","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,13807,112276,"rs35246381-C","rs35246381",0,35246381,"regulatory_region_variant",1,0.23,{"v":3e-202,"d":"3.00E-202"},201.52287874528,"(2.159 ppm/3.324 ppm)",1.1291,"[NR] unit increase","Affymetrix [620456]","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":4e-202,"d":"4.00E-202"},201.397940008672,"(EA)",0.179,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.12,{"v":5e-202,"d":"5.00E-202"},201.301029995663,null,0.185,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":1e-201,"d":"1.00E-201"},201,"(EA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":3E-201,"d":"3.00E-201"},200.52287874528,"(EA)",0.18,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":2E-200,"d":"2.00E-200"},199.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.072,{"v":5e-193,"d":"5.00E-193"},192.301029995663,"(EA)",0.237,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":9e-193,"d":"9.00E-193"},192.04575749056,"(SELE)",0.963,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,73025975,"rs13234131","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13234131-A","rs13234131",0,13234131,"intron_variant",0,0.8853,{"v":4e-191,"d":"4.00E-191"},190.397940008672,null,0.1275,"[0.12-0.14] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[42,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,0.953,{"v":1E-190,"d":"1.00E-190"},190,"(EA)",0.275,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":3e-190,"d":"3.00E-190"},189.52287874528,"(EA)",0.231,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":1e-189,"d":"1.00E-189"},189,"(EA)",0.176,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":1e-188,"d":"1.00E-188"},188,null,0.107,"[NR] unit increase","NR [NR] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":3E-187,"d":"3.00E-187"},186.52287874528,null,0.193,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.32,{"v":1E-182,"d":"1.00E-182"},182,null,0.119,"[NR] unit increase","NR [NR] (imputed)","N"]
[26,"rs58253018",8,126490498,"rs58253018","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs58253018-A","rs58253018",0,58253018,"intron_variant",0,0.3738,{"v":2e-182,"d":"2.00E-182"},181.698970004336,null,0.0984,"[0.092-0.105] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs11820589",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.936,{"v":3e-182,"d":"3.00E-182"},181.52287874528,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.067,{"v":5e-181,"d":"5.00E-181"},180.301029995663,"(EA)",0.24,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,"NR",{"v":5e-181,"d":"5.00E-181"},180.301029995663,null,0.19,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil counts","172,275 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5168,{"v":1E-180,"d":"1.00E-180"},180,null,0.1019119,"[0.095-0.109] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":6e-180,"d":"6.00E-180"},179.221848749616,null,0.1038733,"[0.097-0.111] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs157592",19,45422160,"rs12721051","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs12721051-C","rs12721051",0,12721051,"3_prime_UTR_variant",0,0.8427,{"v":1E-179,"d":"1.00E-179"},179,null,0.1061,"[0.099-0.113] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.288,{"v":2E-179,"d":"2.00E-179"},178.698970004336,"(Trans-ethnic initial)",0.119,"[0.11-0.13] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":2e-178,"d":"2.00E-178"},177.698970004336,null,0.225,"[NR] unit increase","NR [NR] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,"NR",{"v":7E-176,"d":"7.00E-176"},175.154901959985,null,0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.015,{"v":8E-175,"d":"8.00E-175"},174.096910013008,null,0.325,"[0.3-0.35] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,"NR",{"v":1E-173,"d":"1.00E-173"},173,null,0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-171,"d":"2.00E-171"},170.698970004336,{"$nulls":3},"NR [25015711] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":1e-170,"d":"1.00E-170"},170,null,5.65,"[5.24-6.06] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p13.3","SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.24,{"v":2E-170,"d":"2.00E-170"},169.698970004336,null,0.134,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-170,"d":"4.00E-170"},169.397940008672,{"$nulls":3},"NR [2501749] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":1E-169,"d":"1.00E-169"},169,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":2e-168,"d":"2.00E-168"},167.698970004336,null,0.148,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs9355288",6,160865645,"rs7769879","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","SLC22A3",null,null,"ENSG00000146477",null,null,"rs7769879-C","rs7769879",0,7769879,"intron_variant",0,null,{"v":4e-168,"d":"4.00E-168"},167.397940008672,null,6.74,"[6.27-7.21] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,"NR",{"v":4E-167,"d":"4.00E-167"},166.397940008672,null,0.147,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum eosinophil basophil counts","171,771 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5168,{"v":7e-167,"d":"7.00E-167"},166.154901959985,null,0.09799102,"[0.091-0.105] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":4E-165,"d":"4.00E-165"},164.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":2e-164,"d":"2.00E-164"},163.698970004336,"(EA)",0.199,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-164,"d":"2.00E-164"},163.698970004336,{"$nulls":3},"NR [2501543] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":3e-164,"d":"3.00E-164"},163.52287874528,null,0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-164,"d":"4.00E-164"},163.397940008672,null,0.144,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161005610,"rs55730499","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,null,{"v":4e-163,"d":"4.00E-163"},162.397940008672,null,16.77,"[15.63-17.91] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":6e-163,"d":"6.00E-163"},162.221848749616,null,0.163,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1081105",19,45412955,"rs1081105","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1081105-?","rs1081105",0,1081105,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-162,"d":"1.00E-162"},162,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-162,"d":"1.00E-162"},162,"(CUB and zona pellucida-like domain-containing protein 1, CUZD1.7943.16.3)",1.14,"[1.06-1.22] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":3E-162,"d":"3.00E-162"},161.52287874528,null,0.161,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs3925681",19,45421100,"rs3925681","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1",null,null,"ENSG00000130208",null,null,"rs3925681-?","rs3925681",0,3925681,"intron_variant",0,"NR",{"v":7e-162,"d":"7.00E-162"},161.154901959985,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":2e-161,"d":"2.00E-161"},160.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3798,{"v":3E-160,"d":"3.00E-160"},159.52287874528,null,0.0748,"[0.069-0.08] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[48,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.88,{"v":9e-160,"d":"9.00E-160"},159.04575749056,"(EA)",0.191,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":4E-159,"d":"4.00E-159"},158.397940008672,"(Protein CEI, C5orf38.6378.2.3)",0.82,"[0.76-0.88] unit increase","Affymetrix [10572788] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.879,{"v":2e-158,"d":"2.00E-158"},157.698970004336,"(EA)",0.189,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0194,{"v":6E-158,"d":"6.00E-158"},157.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","11q23.3","APO-cluster","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":2e-157,"d":"2.00E-157"},156.698970004336,null,0.244,"[0.23-0.26] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2009-09-29",19734902,"Harold D","2009-09-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19734902","Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.","Alzheimer's disease","3,941 European ancestry cases, 7,848 European ancestry controls","2,023 European ancestry cases, 2,340 European ancestry controls","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,0.15,{"v":2e-157,"d":"2.00E-157"},156.698970004336,null,2.53,"[2.37-2.71]","Illumina [529205]","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":2e-157,"d":"2.00E-157"},156.698970004336,"(EA)",0.174,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-157,"d":"3.00E-157"},156.52287874528,null,0.194,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.885,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.195,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-156,"d":"2.00E-156"},155.698970004336,"(EA)",0.172,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291312,"rs548145","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24367,55477,"rs548145-T","rs548145",0,548145,"intergenic_variant",1,0.2416,{"v":6e-156,"d":"6.00E-156"},155.221848749616,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[50,"rs6859",19,45382034,"rs6859","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs6859-?","rs6859",0,6859,"3_prime_UTR_variant",0,"NR",{"v":1E-155,"d":"1.00E-155"},155,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.6,{"v":9e-155,"d":"9.00E-155"},154.04575749056,"(Triglycerides in very large HDL)",0.26,"[0.24-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[19,"rs55730499",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.069,{"v":3e-154,"d":"3.00E-154"},153.52287874528,null,0.337,"[0.31-0.36] unit increase","Affymetrix [7947838] (imputed)","N"]
[19,"rs55730499",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.0686,{"v":3e-154,"d":"3.00E-154"},153.52287874528,null,0.3368,"[0.31-0.36] unit increase","NR [8041861] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,"NR",{"v":4e-154,"d":"4.00E-154"},153.397940008672,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":9e-154,"d":"9.00E-154"},153.04575749056,null,0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161005610,"rs55730499","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.0693,{"v":1E-153,"d":"1.00E-153"},153,null,0.3122,"[0.29-0.34] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[50,"rs6859",19,45382034,"rs6859","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","PVRL2","NECTIN2",null,null,"ENSG00000130202",null,null,"rs6859-A","rs6859",0,6859,"3_prime_UTR_variant",0,0.4218,{"v":1e-152,"d":"1.00E-152"},152,null,26.320562,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[19,"rs3777411",6,160498049,"rs3777404","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","6q25.3","NR","IGF2R",null,null,"ENSG00000197081",null,null,"rs3777404-A","rs3777404",0,3777404,"intron_variant",0,0.14,{"v":3e-151,"d":"3.00E-151"},150.52287874528,"(Cation-independent mannose-6-phosphate receptor, IGF2R.3676.15.3)",0.85,"[0.79-0.91] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-151,"d":"4.00E-151"},150.397940008672,{"$nulls":3},"NR [25015711] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.346,{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-?","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":1e-149,"d":"1.00E-149"},149,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs157592",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":1e-149,"d":"1.00E-149"},149,null,0.197,"[NR] unit increase","NR [NR] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2012-08-14",22832961,"Kamboh MI","2012-05-15","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/22832961","Genome-wide association study of Alzheimer's disease.","Alzheimer's disease","1,291 European ancestry cases, 938 European ancestry controls","509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls","19q13.32","APOE, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-149,"d":"8.00E-149"},148.096910013008,null,3.45,"[NR]","Illumina [2543888] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3E-148,"d":"3.00E-148"},147.52287874528,"(glucose/mannose)",0.041,"[0.037-0.045] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":4e-148,"d":"4.00E-148"},147.397940008672,"(Cardiotrophin-1, CTF1.13732.79.3)",0.8,"[0.74-0.86] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs33924196",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7181,{"v":7e-148,"d":"7.00E-148"},147.154901959985,null,0.0776,"[0.072-0.083] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-147,"d":"2.00E-147"},146.698970004336,"(VPS29)",1.2477906,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":9e-147,"d":"9.00E-147"},146.04575749056,null,7.14,"[6.57-7.71] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":1E-146,"d":"1.00E-146"},146,null,0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-145,"d":"1.00E-145"},145,null,0.167,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2e-145,"d":"2.00E-145"},144.698970004336,null,0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":1e-144,"d":"1.00E-144"},144,null,0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs28399637",19,45324138,"rs28399637","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","BCAM","BCAM",null,null,"ENSG00000187244",null,null,"rs28399637-A","rs28399637",0,28399637,"intron_variant",0,0.3156,{"v":2e-143,"d":"2.00E-143"},142.698970004336,null,25.508192,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.8416,{"v":1E-142,"d":"1.00E-142"},142,null,0.093,"[0.086-0.1] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":2e-142,"d":"2.00E-142"},141.698970004336,null,0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":7e-142,"d":"7.00E-142"},141.154901959985,null,0.25,"[0.23-0.27] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[41,"rs1077835",15,58723939,"rs2070895","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":1e-140,"d":"1.00E-140"},140,null,0.1322,"[0.12-0.14] unit increase novel","Illumina [6108953] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-140,"d":"4.00E-140"},139.397940008672,null,0.139,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.32,{"v":3e-139,"d":"3.00E-139"},138.52287874528,null,0.1,"[NR] unit increase","NR [NR] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":9e-139,"d":"9.00E-139"},138.04575749056,null,0.236,"[0.22-0.26] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,73001021,"rs35173225","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,7900,6503,"rs35173225-T","rs35173225",0,35173225,"intergenic_variant",1,0.108,{"v":1e-137,"d":"1.00E-137"},137,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-137,"d":"4.00E-137"},136.397940008672,"(Proteasome activator complex subunit 1, PSME1.5918.5.3)",1.06,"[0.98-1.14] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":8e-137,"d":"8.00E-137"},136.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1081105",19,45412955,"rs1081105","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1081105-?","rs1081105",0,1081105,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-136,"d":"1.00E-136"},136,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.288,{"v":3e-136,"d":"3.00E-136"},135.52287874528,"(Trans-ethnic initial)",0.0995,"[0.092-0.107] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-136,"d":"5.00E-136"},135.301029995663,"(EA)",0.195,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.219,{"v":7e-135,"d":"7.00E-135"},134.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":9e-135,"d":"9.00E-135"},134.04575749056,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":2e-134,"d":"2.00E-134"},133.698970004336,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.981,{"v":4e-134,"d":"4.00E-134"},133.397940008672,"(EA)",0.481,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.781,{"v":5e-134,"d":"5.00E-134"},133.301029995663,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte counts","171,643 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5176,{"v":7e-134,"d":"7.00E-134"},133.154901959985,null,0.08836465,"[0.081-0.095] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,"NR",{"v":3e-133,"d":"3.00E-133"},132.52287874528,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":6e-133,"d":"6.00E-133"},132.221848749616,null,8.76,"[7.98-9.54] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.228,{"v":7e-133,"d":"7.00E-133"},132.154901959985,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,"NR",{"v":2E-132,"d":"2.00E-132"},131.698970004336,null,0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":6e-132,"d":"6.00E-132"},131.221848749616,{"$nulls":3},"NR [2501549] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,0.923,{"v":3E-131,"d":"3.00E-131"},130.52287874528,"(EA)",0.24,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,0.22,{"v":6e-131,"d":"6.00E-131"},130.221848749616,null,5.41,"[4.94-5.88] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":9e-131,"d":"9.00E-131"},130.04575749056,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,"NR",{"v":3e-130,"d":"3.00E-130"},129.52287874528,null,0.131,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-129,"d":"1.00E-129"},129,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45415640,"rs445925","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":1e-129,"d":"1.00E-129"},129,"(Asian initial, BMI unadjusted)",0.523,"[0.48-0.56] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs2072560",11,116647607,"rs2160669","2014-05-13",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","8,743 East Asian ancestry individuals","11q23.3","A4, C3, A1, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs2160669-?","rs2160669",0,2160669,"3_prime_UTR_variant",0,0.73,{"v":3e-128,"d":"3.00E-128"},127.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[38,"rs2244608",12,121420807,"rs1183910","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-A","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":6e-128,"d":"6.00E-128"},127.221848749616,{"$nulls":3},"NR [2501749] (imputed)","N"]
[38,"rs2244608",12,121420807,"rs1183910","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-A","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":8e-128,"d":"8.00E-128"},127.096910013008,{"$nulls":3},"NR [2501549] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":1E-127,"d":"1.00E-127"},127,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":2e-127,"d":"2.00E-127"},126.698970004336,null,0.13,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.211,{"v":3e-126,"d":"3.00E-126"},125.52287874528,"(EA)",0.14,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7970695",12,121420260,"rs7979473","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7979473-?","rs7979473",0,7979473,"intron_variant",0,"NR",{"v":3e-126,"d":"3.00E-126"},125.52287874528,null,0.09719,"[0.089-0.105] unit increase novel","Illumina [6108953] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of granulocytes","170,536 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.517,{"v":4e-126,"d":"4.00E-126"},125.397940008672,null,0.08525002,"[0.078-0.092] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":7E-126,"d":"7.00E-126"},125.154901959985,"(EA)",0.142,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":1E-125,"d":"1.00E-125"},125,"(EA)",0.141,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-?","rs261334",0,261334,"intron_variant",0,"NR",{"v":1E-125,"d":"1.00E-125"},125,"(Triglycerides in very large HDL, conditioned)",0.2686627,"[0.25-0.29] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":2E-125,"d":"2.00E-125"},124.698970004336,null,0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.725,{"v":2E-125,"d":"2.00E-125"},124.698970004336,"(Asian initial, BMI unadjusted)",0.279,"[0.26-0.3] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[42,"rs11076174",16,57003146,"rs11076174","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs11076174-T","rs11076174",0,11076174,"intron_variant",0,"NR",{"v":2E-125,"d":"2.00E-125"},124.698970004336,null,0.149,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,0.688,{"v":7E-125,"d":"7.00E-125"},124.154901959985,"(EA)",0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":8e-125,"d":"8.00E-125"},124.096910013008,"(ADGRF5)",0.815,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[38,"rs2244608",12,121420807,"rs1183910","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-G","rs1183910",0,1183910,"intron_variant",0,"NR",{"v":2e-124,"d":"2.00E-124"},123.698970004336,null,0.149,"[0.14-0.16] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":3E-124,"d":"3.00E-124"},123.52287874528,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":1e-123,"d":"1.00E-123"},123,"(EA)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs2986164",1,25747230,"rs586178","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","1p36.11",null,"RHCE",null,null,"ENSG00000188672",null,null,"rs586178-?","rs586178",0,586178,"missense_variant",0,"NR",{"v":3e-123,"d":"3.00E-123"},122.52287874528,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (alkaline phosphatase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.8,{"v":3e-123,"d":"3.00E-123"},122.52287874528,null,8.8,"[7.40-10.2] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,0.92,{"v":2e-122,"d":"2.00E-122"},121.698970004336,"(EA)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-122,"d":"8.00E-122"},121.096910013008,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-121,"d":"1.00E-121"},121,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":2E-121,"d":"2.00E-121"},120.698970004336,null,0.126,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs1692821",8,11705870,"rs1736089","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1736089-G","rs1736089",0,1736089,"non_coding_transcript_exon_variant",0,0.748,{"v":2E-121,"d":"2.00E-121"},120.698970004336,"(CTSB)",0.612,"[0.56-0.66] unit decrease","Illumina [> 1000000] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-A","rs2954022",0,2954022,"intron_variant",0,0.47,{"v":7e-121,"d":"7.00E-121"},120.154901959985,"(Trans-ethnic initial)",0.078,"[0.072-0.084] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[41,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":8e-121,"d":"8.00E-121"},120.096910013008,null,0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-120,"d":"1.00E-120"},120,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06,{"v":2E-120,"d":"2.00E-120"},119.698970004336,"(Free cholesterol in large LDL)",0.59,"[0.53-0.65] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2E-120,"d":"2.00E-120"},119.698970004336,"(Selenoprotein S, VIMP.11286.78.3)",1.01,"[0.93-1.09] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":2E-120,"d":"2.00E-120"},119.698970004336,null,0.137,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Eosinophil percentage of white cells","172,378 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5168,{"v":3e-120,"d":"3.00E-120"},119.52287874528,null,0.08283769,"[0.076-0.09] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":3e-120,"d":"3.00E-120"},119.52287874528,null,0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":6e-120,"d":"6.00E-120"},119.221848749616,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs28399637",19,45324138,"rs28399637","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCAM",null,null,"ENSG00000187244",null,null,"rs28399637-?","rs28399637",0,28399637,"intron_variant",0,"NR",{"v":7e-120,"d":"7.00E-120"},119.154901959985,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":1E-119,"d":"1.00E-119"},119,null,0.208,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-119,"d":"1.00E-119"},119,"(Quinone oxidoreductase-like protein 1, CRYZL1.9207.60.3)",1,"[0.92-1.08] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.189,{"v":3e-119,"d":"3.00E-119"},118.52287874528,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs6938647",6,160986915,"rs6938647","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs6938647-A","rs6938647",0,6938647,"intron_variant",0,null,{"v":7e-119,"d":"7.00E-119"},118.154901959985,null,5.47,"[4.76-6.18] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-G","rs668948",0,668948,"intergenic_variant",1,0.19,{"v":1e-118,"d":"1.00E-118"},118,"(EA)",0.135,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":3e-118,"d":"3.00E-118"},117.52287874528,null,0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":2e-117,"d":"2.00E-117"},116.698970004336,null,0.08,"[0.08-0.09] unit increase","Illumina [4642479] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":4e-117,"d":"4.00E-117"},116.397940008672,null,6.99,"[6.4-7.58] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.191,{"v":8e-117,"d":"8.00E-117"},116.096910013008,"(EA)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":8e-117,"d":"8.00E-117"},116.096910013008,null,0.089,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-116,"d":"2.00E-116"},115.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-116,"d":"3.00E-116"},115.52287874528,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":7e-116,"d":"7.00E-116"},115.154901959985,null,0.101,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2014-12-02",24755620,"Perez-Palma E","2014-04-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24755620","Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.","Alzheimer's disease","2,540 European ancestry cases, 2,029 European ancestry controls","NA","19q13.32","APOE, BCAM, PVR, EXOC3L2, TOMM40, PVRL2, BCL3, APOC1","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,null,{"v":9e-116,"d":"9.00E-116"},115.04575749056,null,4.48,"[NR]","Affymetrix, Illumina [1216213] (imputed)","N"]
[8,"rs62122520",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,"NR",{"v":1e-115,"d":"1.00E-115"},115,null,0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.192,{"v":2e-115,"d":"2.00E-115"},114.698970004336,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","up to 4,420 African ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-?","rs6511720",0,6511720,"intron_variant",0,0.13,{"v":3e-115,"d":"3.00E-115"},114.52287874528,{"$nulls":3},"NR [NR] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.192,{"v":5e-115,"d":"5.00E-115"},114.301029995663,"(EA)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1e-114,"d":"1.00E-114"},114,"(ROBO4)",0.73,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hypothyroidism","approximately 459,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-114,"d":"1.00E-114"},114,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.777,{"v":2e-114,"d":"2.00E-114"},113.698970004336,"(Complement C1q tumor necrosis factor-related protein 1, C1QTNF1.6304.8.3)",0.64,"[0.58-0.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-114,"d":"2.00E-114"},113.698970004336,null,0.162,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.3,{"v":4e-114,"d":"4.00E-114"},113.397940008672,null,4.05,"[3.68-4.42] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":6e-114,"d":"6.00E-114"},113.221848749616,"(EA)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.3261,{"v":1e-113,"d":"1.00E-113"},113,null,0.26576465,"[0.24-0.29] mg/dl increase","Illumina [24111857] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.89,{"v":2E-113,"d":"2.00E-113"},112.698970004336,null,0.217,"[0.2-0.24] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2E-113,"d":"2.00E-113"},112.698970004336,"(EA)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":1e-112,"d":"1.00E-112"},112,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":3e-112,"d":"3.00E-112"},111.52287874528,null,0.119,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63107526,"rs995000","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.3454,{"v":6e-112,"d":"6.00E-112"},111.221848749616,null,0.0618,"[0.056-0.067] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.17,{"v":5e-111,"d":"5.00E-111"},110.301029995663,null,6.83,"[6.2-7.46] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[51,"rs35106244",19,49206674,"rs601338","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs601338-A","rs601338",0,601338,"stop_gained",0,0.507,{"v":9e-111,"d":"9.00E-111"},110.04575749056,"(Protein FAM3D, FAM3D.13102.1.3)",0.51,"[0.47-0.55] unit decrease","Affymetrix [10572788] (imputed)","N"]
[20,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs34121855",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,"NR",{"v":1e-110,"d":"1.00E-110"},110,null,0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.117,{"v":2e-110,"d":"2.00E-110"},109.698970004336,"(Trans-ethnic initial)",0.115,"[0.1-0.13] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":7e-110,"d":"7.00E-110"},109.154901959985,null,0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,"NR",{"v":2E-109,"d":"2.00E-109"},108.698970004336,null,0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":3e-109,"d":"3.00E-109"},108.52287874528,"(EA)",0.129,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,0.688,{"v":5e-109,"d":"5.00E-109"},108.301029995663,"(EA)",0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58680178,"rs261291","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-?","rs261291",0,261291,"intron_variant",0,"NR",{"v":7e-109,"d":"7.00E-109"},108.154901959985,null,0.1158,"[0.11-0.13] unit increase novel","Illumina [6108953] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,null,0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":2e-108,"d":"2.00E-108"},107.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of granulocytes","170,672 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.517,{"v":5E-108,"d":"5.00E-108"},107.301029995663,null,0.07881358,"[0.072-0.086] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":1E-107,"d":"1.00E-107"},107,null,0.076,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[26,"rs112875651",8,126500031,"rs28601761","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.5747,{"v":4e-106,"d":"4.00E-106"},105.397940008672,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[35,"rs11600380",11,116665079,"rs9804646","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","NR","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,1943,18841,"rs9804646-?","rs9804646",0,9804646,"intergenic_variant",1,"NR",{"v":5e-106,"d":"5.00E-106"},105.301029995663,null,0.1509,"[0.14-0.16] unit decrease novel","Illumina [6108953] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","RP11-115J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1054,{"v":1e-105,"d":"1.00E-105"},105,null,0.0954,"[0.087-0.104] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs58065809",11,116999225,"rs9326248","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","11q23.3","RP11-109L13.1, TAGLN, PCSK7, PAFAH1B2, SIDT2, RP11-109L13.5, AP000892.6","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,9328,7019,"rs9326248-T","rs9326248",0,9326248,"intergenic_variant",1,0.2386935,{"v":2e-105,"d":"2.00E-105"},104.698970004336,"(Proprotein convertase subtilisin/kexin type 7)",0.9929,"[0.91-1.07] unit decrease","Affymetrix [509946]","N"]
[19,"rs56393506",6,161089307,"rs56393506","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","AL109933.2",null,null,"ENSG00000243831",null,null,"rs56393506-T","rs56393506",0,56393506,"intron_variant",0,null,{"v":3e-105,"d":"3.00E-105"},104.52287874528,null,7.07,"[6.37-7.77] unit increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-04-30",28714976,"Sims R","2017-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714976","Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.","Alzheimer's disease (late onset)","up to 16,097 European ancestry cases, up to 18,077 European ancestry controls","up to 20,693 European ancestry cases, up to 30,266 European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-105,"d":"3.00E-105"},104.52287874528,null,2.3065467,null,"Illumina [241551]","N"]
[19,"rs139399782",6,161137663,"rs4252109","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q26","LPA","PLG",null,null,"ENSG00000122194",null,null,"rs4252109-G","rs4252109",0,4252109,"intron_variant",0,null,{"v":5e-105,"d":"5.00E-105"},104.301029995663,null,4.91,"[4.32-5.5] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[41,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,"NR",{"v":5e-105,"d":"5.00E-105"},104.301029995663,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs34121855",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,"NR",{"v":6e-105,"d":"6.00E-105"},104.221848749616,null,0.106,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":8e-105,"d":"8.00E-105"},104.096910013008,"(EA)",0.102,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":9e-105,"d":"9.00E-105"},104.04575749056,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":7e-104,"d":"7.00E-104"},103.154901959985,null,0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-?","rs1532085",0,1532085,"intron_variant",0,0.44,{"v":9e-104,"d":"9.00E-104"},103.04575749056,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":1e-103,"d":"1.00E-103"},103,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-102,"d":"1.00E-102"},102,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[41,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,"NR",{"v":2e-102,"d":"2.00E-102"},101.698970004336,null,0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs62122520",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,"NR",{"v":3e-101,"d":"3.00E-101"},100.52287874528,null,0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.784,{"v":6e-101,"d":"6.00E-101"},100.221848749616,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":8e-101,"d":"8.00E-101"},100.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[41,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.784,{"v":8e-101,"d":"8.00E-101"},100.096910013008,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.787,{"v":2E-100,"d":"2.00E-100"},99.698970004336,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs62122520",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,0.677,{"v":3e-100,"d":"3.00E-100"},99.5228787452803,"(EA)",0.107,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.67,{"v":4e-100,"d":"4.00E-100"},99.397940008672,null,0.32,"[0.29-0.35] µg/mL increase","Illumina [NR] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":6e-100,"d":"6.00E-100"},99.2218487496163,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":7e-100,"d":"7.00E-100"},99.1549019599857,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.88,{"v":1E-99,"d":"1.00E-99"},99,"(EA)",0.135,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.07994,{"v":1E-99,"d":"1.00E-99"},99,null,21.199877,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-99,"d":"1.00E-99"},99,"(Cardiotrophin-1, CTF1.13732.79.3)",0.92,"[0.84-1] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.205,{"v":2E-99,"d":"2.00E-99"},98.698970004336,"(EA)",0.12,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":9e-99,"d":"9.00E-99"},98.0457574905606,null,0.115,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[41,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.65,{"v":3E-98,"d":"3.00E-98"},97.5228787452803,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.378,{"v":4e-98,"d":"4.00E-98"},97.397940008672,"(EA)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57002732,"rs9939224","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs9939224-?","rs9939224",0,9939224,"intron_variant",0,"NR",{"v":1E-97,"d":"1.00E-97"},97,null,0.1861,"[0.17-0.2] unit decrease novel","Illumina [6108953] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1E-97,"d":"1.00E-97"},97,"(Hemoglobin subunit theta-1, HBQ1.7965.25.3)",0.92,"[0.84-1] unit decrease","Affymetrix [10572788] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.17,{"v":2e-97,"d":"2.00E-97"},96.698970004336,null,3.353,"[3.04-3.66] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[50,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,0.846,{"v":3e-97,"d":"3.00E-97"},96.5228787452803,"(EA)",0.136,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.209,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(EA)",0.097,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-A","rs247617",0,247617,"regulatory_region_variant",1,0.3,{"v":6e-97,"d":"6.00E-97"},96.2218487496163,"(Total cholesterol in HDL)",0.23,"[0.21-0.25] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.11,{"v":7e-97,"d":"7.00E-97"},96.1549019599857,null,7.09,"[6.42-7.76] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[20,"rs34121855",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.809,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1e-96,"d":"1.00E-96"},96,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":1e-96,"d":"1.00E-96"},96,"(E-Selectin)",0.9436,"[0.86-1.02] unit decrease","Affymetrix [509946]","N"]
[20,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.821,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(EA)",0.114,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":2e-96,"d":"2.00E-96"},95.698970004336,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":2e-96,"d":"2.00E-96"},95.698970004336,"(PH and SEC7 domain-containing protein 1, PSD.13055.53.3)",0.66,"[0.6-0.72] unit increase","Affymetrix [10572788] (imputed)","N"]
[41,"rs261290",15,58678512,"rs10468017","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-C","rs10468017",0,10468017,"intron_variant",0,0.715,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.39,{"v":3e-96,"d":"3.00E-96"},95.5228787452803,null,1.45,"[1.29-1.61] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-A","rs1367117",0,1367117,"missense_variant",0,0.3,{"v":4e-96,"d":"4.00E-96"},95.397940008672,null,4.16,"[3.73-4.59] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[41,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":6e-96,"d":"6.00E-96"},95.2218487496163,null,0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs34121855",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.81,{"v":2E-95,"d":"2.00E-95"},94.698970004336,"(EA)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":3e-95,"d":"3.00E-95"},94.5228787452803,null,0.09,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.569,{"v":3e-95,"d":"3.00E-95"},94.5228787452803,"(Trans-ethnic initial)",0.0733,"[0.066-0.081] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-95,"d":"5.00E-95"},94.3010299956639,"(EA)",0.159,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs11076174",16,57003146,"rs11076174","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs11076174-T","rs11076174",0,11076174,"intron_variant",0,0.918,{"v":6e-95,"d":"6.00E-95"},94.2218487496163,"(EA)",0.145,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":9e-95,"d":"9.00E-95"},94.0457574905606,null,0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-94,"d":"2.00E-94"},93.698970004336,null,0.08881,"[0.08-0.097] unit decrease novel","Illumina [6108953] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.094,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":3e-94,"d":"3.00E-94"},93.5228787452803,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,"NR",{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.167,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2017-05-23",28247064,"Deming Y","2017-02-28","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/28247064","Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.","Cerebrospinal fluid AB1-42 levels","3,146 individuals","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.191,{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.101,"[0.091-0.111] unit decrease","Illumina [7358575] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0779,{"v":5e-94,"d":"5.00E-94"},93.3010299956639,null,0.41957754,"[0.38-0.46] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-T","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.7072,{"v":6e-94,"d":"6.00E-94"},93.2218487496163,null,0.0604,"[0.055-0.066] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":6e-94,"d":"6.00E-94"},93.2218487496163,"(EA)",0.085,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.6225,{"v":7E-94,"d":"7.00E-94"},93.1549019599857,null,0.0556,"[0.05-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[42,"rs3816117",16,57005479,"rs1532624","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-C","rs1532624",0,1532624,"intron_variant",0,0.57,{"v":9e-94,"d":"9.00E-94"},93.0457574905606,null,0.21,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[35,"rs11820589",11,116662407,"rs3135506","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-C","rs3135506",0,3135506,"missense_variant",0,0.071,{"v":2e-93,"d":"2.00E-93"},92.698970004336,null,0.1053,"[0.095-0.115] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs4149307",9,107589744,"rs4149307","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149307-T","rs4149307",0,4149307,"intron_variant",0,0.3233,{"v":3e-93,"d":"3.00E-93"},92.5228787452803,null,0.0685,"[0.062-0.075] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":3e-93,"d":"3.00E-93"},92.5228787452803,"(HDL-C.assay, whole)",3.096,"[NR] unit increase","Illumina [335603]","N"]
[42,"rs3816117",16,56995236,"rs1800775","2009-12-29",20031564,"Ridker PM","2009-02-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031564","Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.","HDL cholesterol","18,245 European ancestry females","NA","16q13","SLC12A3, HERPUD1, CETP, NUP93","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.49,{"v":4e-93,"d":"4.00E-93"},92.397940008672,null,3.09,"mg/dL increase","Illumina [~ 318237]","N"]
[3,"rs11591147",1,55505647,"rs11591147","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.98,{"v":2E-92,"d":"2.00E-92"},91.698970004336,null,0.528,"[0.48-0.58] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2E-92,"d":"2.00E-92"},91.698970004336,"(C5orf38)",1.016853,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63107526,"rs995000","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs995000-T","rs995000",0,995000,"intron_variant",0,0.309,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,"(Trans-ethnic initial)",0.0691,"[0.062-0.076] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-92,"d":"3.00E-92"},91.5228787452803,null,0.073,"[0.065-0.081] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[19,"rs186696265",6,161111700,"rs186696265","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","6q26","intergenic","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-T","rs186696265",0,186696265,"intergenic_variant",1,0.0131,{"v":5e-92,"d":"5.00E-92"},91.3010299956639,null,0.5467,"[0.49-0.6] unit increase","NR [8041861] (imputed)","N"]
[26,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":6e-92,"d":"6.00E-92"},91.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":7e-92,"d":"7.00E-92"},91.1549019599857,null,0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,0.146,"[0.13-0.16] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":2E-91,"d":"2.00E-91"},90.698970004336,"(EA)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2E-91,"d":"2.00E-91"},90.698970004336,null,3.9972339,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":3e-91,"d":"3.00E-91"},90.5228787452803,"(EA)",0.09,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":4e-91,"d":"4.00E-91"},90.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[14,"rs4704210",5,74656539,"rs12916","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.569,{"v":5E-91,"d":"5.00E-91"},90.3010299956639,"(Trans-ethnic initial)",0.0684,"[0.061-0.075] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,"NR",{"v":5E-91,"d":"5.00E-91"},90.3010299956639,null,0.19,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":7e-91,"d":"7.00E-91"},90.1549019599857,null,0.0724115,"[0.065-0.079] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2E-90,"d":"2.00E-90"},89.698970004336,"(Ubiquitin carboxyl-terminal hydrolase 21, USP21.12681.63.3)",0.49,"[0.45-0.53] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-90,"d":"3.00E-90"},89.5228787452803,"(Inactive gamma-glutamyltranspeptidase 2, GGT2.6334.9.3)",0.88,"[0.8-0.96] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs3925681",19,45421100,"rs3925681","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOC1",null,null,"ENSG00000130208",null,null,"rs3925681-?","rs3925681",0,3925681,"intron_variant",0,"NR",{"v":3e-90,"d":"3.00E-90"},89.5228787452803,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,"NR",{"v":4E-90,"d":"4.00E-90"},89.397940008672,null,0.118,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2011-06-23",21627779,"Antunez C","2011-05-31","Genome Med","www.ncbi.nlm.nih.gov/pubmed/21627779","The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.","Alzheimer's disease","319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls","4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls","19q13.32","APOE","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":8e-89,"d":"8.00E-89"},88.096910013008,null,1.69,"[NR]","Affymetrix, Illumina [696707] (imputed)","N"]
[8,"rs62122520",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,0.677,{"v":3e-88,"d":"3.00E-88"},87.5228787452803,"(EA)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.36,{"v":5e-88,"d":"5.00E-88"},87.3010299956639,null,0.123,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[19,"rs6938647",6,160986915,"rs6938647","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs6938647-A","rs6938647",0,6938647,"intron_variant",0,null,{"v":2E-87,"d":"2.00E-87"},86.698970004336,null,5.48,"[4.89-6.07] unit decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":3e-87,"d":"3.00E-87"},86.5228787452803,{"$nulls":3},"NR [2501543] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3e-87,"d":"3.00E-87"},86.5228787452803,"(ARL2)",0.97562826,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.274,{"v":4e-87,"d":"4.00E-87"},86.397940008672,"(East Asian)",0.32,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":5e-87,"d":"5.00E-87"},86.3010299956639,"(HDL.large, whole)",0.729,"[NR] unit increase","Illumina [335603]","N"]
[41,"rs261290",15,58680178,"rs261291","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-C","rs261291",0,261291,"intron_variant",0,0.37,{"v":6e-87,"d":"6.00E-87"},86.2218487496163,null,0.122,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63124465,"rs4495740","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs4495740-T","rs4495740",0,4495740,"intron_variant",0,0.6678,{"v":2e-86,"d":"2.00E-86"},85.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[35,"rs1145208",11,116654435,"rs603446","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Triglycerides","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13","ZPR1",null,null,"ENSG00000109917",null,null,"rs603446-T","rs603446",0,603446,"intron_variant",0,0.23,{"v":2e-86,"d":"2.00E-86"},85.698970004336,null,0.0876,"[0.079-0.096] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(EA)",0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.4,{"v":9e-86,"d":"9.00E-86"},85.0457574905606,"(BMI-adjusted)",0.077,"[0.069-0.085] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","HDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-G","rs662799",0,662799,"intergenic_variant",1,0.28,{"v":2E-85,"d":"2.00E-85"},84.698970004336,null,2.516,"[2.27-2.76] unit decrease","Affymetrix, Illumina [2573667] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":3e-85,"d":"3.00E-85"},84.5228787452803,null,0.142,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.243,{"v":7e-85,"d":"7.00E-85"},84.1549019599857,"(Trans-ethnic initial)",0.0698,"[0.062-0.078] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs508487",11,117075566,"rs508487","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-C","rs508487",0,508487,"3_prime_UTR_variant",0,0.945,{"v":9e-85,"d":"9.00E-85"},84.0457574905606,"(EA)",0.193,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56991363,"rs183130","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","16q13","intergenic","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,12588,4399,"rs183130-T","rs183130",0,183130,"intergenic_variant",1,0.3073,{"v":1E-84,"d":"1.00E-84"},84,null,0.0549,"[0.049-0.06] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[41,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.707,{"v":5e-84,"d":"5.00E-84"},83.3010299956639,"(EA)",0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","Triglyceride levels","1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":7e-84,"d":"7.00E-84"},83.1549019599857,"(additive)",32.91,"[29.62-36.20] unit increase","Affymetrix [583469]","N"]
[20,"7:73042302_GCTTT_G",7,73058017,"rs7777102","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,19144,24138,"rs7777102-A","rs7777102",0,7777102,"intergenic_variant",1,0.874,{"v":8e-84,"d":"8.00E-84"},83.096910013008,"(EA)",0.127,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.6022,{"v":1E-83,"d":"1.00E-83"},83,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-83,"d":"2.00E-83"},82.698970004336,null,3.8717523,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[22,"rs11250098",8,10957723,"rs2409701","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8p23.1",null,"XKR6",null,null,"ENSG00000171044",null,null,"rs2409701-?","rs2409701",0,2409701,"intron_variant",0,"NR",{"v":3e-83,"d":"3.00E-83"},82.5228787452803,null,0.0393467,"[0.035-0.043] unit increase","Affymetrix [20259828] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Triglycerides","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":3e-83,"d":"3.00E-83"},82.5228787452803,"(Hispanic)",0.275,"[0.25-0.3] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[50,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,"NR",{"v":6e-83,"d":"6.00E-83"},82.2218487496163,null,0.232,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2010-03-17",20147318,"Qi L","2010-02-22","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20147318","Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes.","E-selectin levels","501 European ancestry type 2 diabetes female cases, 504 European ancestry female controls","518 European ancestry female individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.22,{"v":2e-82,"d":"2.00E-82"},81.698970004336,null,17.23,"[NR] ng/ml decrease","Affymetrix [721316]","N"]
[4,"1:62980399_CACA_C",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.295,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,"(Trans-ethnic initial)",0.0758,"[0.069-0.083] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[26,"rs2954021",8,126478450,"rs2001846","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","intergenic","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,27803,731,"rs2001846-T","rs2001846",0,2001846,"intergenic_variant",1,0.4479,{"v":3e-82,"d":"3.00E-82"},81.5228787452803,null,0.0539,"[0.048-0.059] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs157595",19,45425460,"rs157595","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-A","rs157595",0,157595,"intergenic_variant",1,0.39,{"v":5e-82,"d":"5.00E-82"},81.3010299956639,null,0.096,"[0.086-0.106] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":1e-81,"d":"1.00E-81"},81,"(HDL-C.by.NMR, whole)",2.658,"[NR] unit increase","Illumina [335603]","N"]
[25,"rs4876611",8,116663898,"rs2737252","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","8q23.3",null,"TRPS1",null,null,"ENSG00000104447",null,null,"rs2737252-?","rs2737252",0,2737252,"intron_variant",0,"NR",{"v":3e-81,"d":"3.00E-81"},80.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":4e-81,"d":"4.00E-81"},80.397940008672,"(Guanine nucleotide-binding protein G(k) subunit alpha, GNAI3.12650.43.3)",0.84,"[0.76-0.92] unit increase","Affymetrix [10572788] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":5e-81,"d":"5.00E-81"},80.3010299956639,"(IL3RA)",0.613,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[41,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.344,{"v":5e-81,"d":"5.00E-81"},80.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-80,"d":"2.00E-80"},79.698970004336,"(CUZD1)",0.9441912,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":4e-80,"d":"4.00E-80"},79.397940008672,null,0.075,"[NR] unit decrease","NR [NR] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":4e-80,"d":"4.00E-80"},79.397940008672,"(Vascular endothelial growth factor receptor 2, KDR.3651.50.5)",0.58,"[0.52-0.64] unit decrease","Affymetrix [10572788] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,"NR",{"v":4E-79,"d":"4.00E-79"},78.397940008672,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2E-78,"d":"2.00E-78"},77.698970004336,"(women)",0.09,"[NR] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[50,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,0.964,{"v":2E-78,"d":"2.00E-78"},77.698970004336,"(EA)",0.237,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":3e-78,"d":"3.00E-78"},77.5228787452803,"(EA)",0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","15q21.3","ALDH1A2","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-A","rs7350789",0,7350789,"intron_variant",0,0.3451,{"v":4E-78,"d":"4.00E-78"},77.397940008672,null,0.0522,"[0.047-0.058] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[14,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":5e-78,"d":"5.00E-78"},77.3010299956639,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,"NR",{"v":7e-78,"d":"7.00E-78"},77.1549019599857,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.4,{"v":8E-78,"d":"8.00E-78"},77.096910013008,null,0.073,"[NR] unit increase","NR [NR] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":8E-78,"d":"8.00E-78"},77.096910013008,"(HDL.mean.size, whole)",0.086,"[NR] unit increase","Illumina [335603]","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.06071,{"v":8E-78,"d":"8.00E-78"},77.096910013008,null,17.11,"[15.31-18.91] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-77,"d":"1.00E-77"},77,"(mannose)",0.044,"[0.04-0.048] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[14,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,"NR",{"v":1e-77,"d":"1.00E-77"},77,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":1e-77,"d":"1.00E-77"},77,"(Trans-ethnic initial)",0.0622,"[0.055-0.069] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":4e-77,"d":"4.00E-77"},76.397940008672,null,0.137,"[NR] unit decrease","NR [NR] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":5e-77,"d":"5.00E-77"},76.3010299956639,"(EA)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":6e-77,"d":"6.00E-77"},76.2218487496163,null,3.2625577,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":9e-77,"d":"9.00E-77"},76.0457574905606,null,3.2591338,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[37,"rs4766578",12,111865049,"rs7310615","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Autoimmune traits","approximately 459,000 European ancestry individuals","NA","12q24.12",null,"SH2B3",null,null,"ENSG00000111252",null,null,"rs7310615-?","rs7310615",0,7310615,"intron_variant",0,"NR",{"v":2e-76,"d":"2.00E-76"},75.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-76,"d":"2.00E-76"},75.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-?","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":3e-76,"d":"3.00E-76"},75.5228787452803,null,0.1081,"[0.097-0.12] unit decrease novel","Illumina [6108953] (imputed)","N"]
[41,"rs261290",15,58680643,"rs35853021","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs35853021-?","rs35853021",0,35853021,"intron_variant",0,"NR",{"v":7e-76,"d":"7.00E-76"},75.1549019599857,"(XL-HDL-TG)",0.31,"[0.27-0.35] unit increase","Illumina [~ 7700000] (imputed)","N"]
[10,"rs11887534",2,44066247,"rs11887534","2017-03-10",27094239,"Joshi AD","2016-04-16","Gastroenterology","www.ncbi.nlm.nih.gov/pubmed/27094239","Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.","Gallstone disease","8,720 European ancestry cases,  55,152 European ancestry controls","6,489 European ancestry cases, 62,797 European ancestry controls, 1,499 African American cases, 9,145 African American controls, 1,056 Hispanic cases, 2,403 Hispanic controls","2p21","ABCG8, D19H","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-C","rs11887534",0,11887534,"missense_variant",0,0.07,{"v":2e-75,"d":"2.00E-75"},74.698970004336,"(EA)",1.78,"[1.70–1.86]","Affymetrix, Illumina [at least 2305318] (imputed)","N"]
[35,"rs5130",11,116704178,"rs7123454","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","NR","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,390,2289,"rs7123454-?","rs7123454",0,7123454,"intergenic_variant",1,"NR",{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.08217,"[0.073-0.091] unit increase novel","Illumina [6108953] (imputed)","N"]
[37,"rs4766578",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5029,{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.06562279,"[0.059-0.073] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-75,"d":"3.00E-75"},74.5228787452803,null,0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-T","rs173539",0,173539,"intergenic_variant",1,0.32,{"v":4e-75,"d":"4.00E-75"},74.397940008672,null,0.25,"[0.21-0.29] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5e-75,"d":"5.00E-75"},74.3010299956639,"(Trans-ethnic initial)",0.137,"[0.12-0.15] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs6859",19,45382034,"rs6859","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs6859-?","rs6859",0,6859,"3_prime_UTR_variant",0,"NR",{"v":6e-75,"d":"6.00E-75"},74.2218487496163,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":1e-74,"d":"1.00E-74"},74,null,0.06470062,"[0.058-0.072] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.845,{"v":1e-74,"d":"1.00E-74"},74,null,0.0566,"[0.051-0.063] unit decrease","Affymetrix [11535925] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.169,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Asian initial, BMI unadjusted)",0.262,"[0.23-0.29] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[47,"rs9304381",18,47181668,"rs2156552","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.178,{"v":2e-74,"d":"2.00E-74"},73.698970004336,"(Trans-ethnic initial)",0.0793,"[0.07-0.088] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.066,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[42,"rs289713",16,57000885,"rs12720922","2018-06-06",29728394,"Blauw LL","2018-05-01","Circ Genom Precis Med","www.ncbi.nlm.nih.gov/pubmed/29728394","CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.","Cholesteryl ester transfer protein levels","4248 individuals","1458 individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-A","rs12720922",0,12720922,"intron_variant",0,0.17,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,null,0.35,"[0.31-0.39] µg/mL increase","Illumina [NR] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":3e-74,"d":"3.00E-74"},73.5228787452803,"(Collectin-10, COLEC10.6558.5.3)",0.81,"[0.73-0.89] unit increase","Affymetrix [10572788] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.4,{"v":5E-74,"d":"5.00E-74"},73.3010299956639,null,0.68,"[NR] unit increase","NR [NR] (imputed)","N"]
[50,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.981,{"v":6e-74,"d":"6.00E-74"},73.2218487496163,"(EA)",0.347,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","HDL cholesterol","2,758 European ancestry individuals","18,554 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.51,{"v":1E-73,"d":"1.00E-73"},73,null,0.18,"[0.16-0.20] unit decrease","Affymetrix [389878]","N"]
[50,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,0.923,{"v":1E-73,"d":"1.00E-73"},73,"(EA)",0.175,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p21","ABCG8, ABCG5","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.31,{"v":3e-73,"d":"3.00E-73"},72.5228787452803,null,0.079,"[NR] unit increase","NR [NR] (imputed)","N"]
[47,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":3e-73,"d":"3.00E-73"},72.5228787452803,null,0.2326,"[0.21-0.26] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":4E-73,"d":"4.00E-73"},72.397940008672,"(QSOX2)",0.625,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":1e-72,"d":"1.00E-72"},72,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-T","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.7073,{"v":1e-72,"d":"1.00E-72"},72,null,0.053,"[0.047-0.059] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[49,"rs58542926",19,19379549,"rs58542926","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.0692,{"v":3e-72,"d":"3.00E-72"},71.5228787452803,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","2p21","ABCG5, ABCG58","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.31,{"v":4e-72,"d":"4.00E-72"},71.397940008672,null,0.081,"[NR] unit increase","NR [NR] (imputed)","N"]
[50,"rs111606839",19,45452812,"rs1130742","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC2, APOC4-APOC2",null,null,"ENSG00000234906, ENSG00000224916",null,null,"rs1130742-T","rs1130742",0,1130742,"3_prime_UTR_variant",0,0.261,{"v":5e-72,"d":"5.00E-72"},71.3010299956639,"(PH and SEC7 domain-containing protein 2, PSD2.9118.7.3)",0.49,"[0.43-0.55] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":7E-72,"d":"7.00E-72"},71.1549019599857,null,0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hematocrit","173,039 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":8e-72,"d":"8.00E-72"},71.096910013008,null,0.06311912,"[0.056-0.07] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs28399637",19,45324138,"rs28399637","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","BCAM",null,null,"ENSG00000187244",null,null,"rs28399637-?","rs28399637",0,28399637,"intron_variant",0,"NR",{"v":8e-72,"d":"8.00E-72"},71.096910013008,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,"NR",{"v":1e-71,"d":"1.00E-71"},71,null,0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206145,"rs516316","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Mumps","31,227 European ancestry cases, 54,153 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs516316-C","rs516316",0,516316,"intron_variant",0,0.48,{"v":1e-71,"d":"1.00E-71"},71,null,1.25,"[1.24-1.27]","Illumina [at least 560000] (imputed)","N"]
[8,"rs4564803",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-71,"d":"2.00E-71"},70.698970004336,null,0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.725,{"v":2e-71,"d":"2.00E-71"},70.698970004336,"(Asian initial, BMI unadjusted)",0.182,"[0.16-0.2] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":2e-71,"d":"2.00E-71"},70.698970004336,null,3.2239969,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.92,{"v":3e-71,"d":"3.00E-71"},70.5228787452803,"(Trans-ethnic initial)",0.1,"[0.086-0.114] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":4e-71,"d":"4.00E-71"},70.397940008672,null,0.1558,"[0.14-0.17] unit increase novel","Illumina [6108953] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":5E-71,"d":"5.00E-71"},70.3010299956639,"(Trans-ethnic initial)",0.121,"[0.11-0.13] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":9e-71,"d":"9.00E-71"},70.0457574905606,null,0.102,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":1E-70,"d":"1.00E-70"},70,null,0.08,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs60049679",19,45429708,"rs60049679","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,7102,353,"rs60049679-?","rs60049679",0,60049679,"regulatory_region_variant",1,"NR",{"v":2E-70,"d":"2.00E-70"},69.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs60049679",19,45429708,"rs60049679","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,7102,353,"rs60049679-?","rs60049679",0,60049679,"regulatory_region_variant",1,"NR",{"v":2E-70,"d":"2.00E-70"},69.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-70,"d":"3.00E-70"},69.5228787452803,null,0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,"NR",{"v":3e-70,"d":"3.00E-70"},69.5228787452803,null,0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":3e-70,"d":"3.00E-70"},69.5228787452803,"(INSR)",0.595,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-?","rs173539",0,173539,"intergenic_variant",1,0.28,{"v":3e-70,"d":"3.00E-70"},69.5228787452803,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[35,"rs2000571",11,116581641,"rs2367970","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,52673,37245,"rs2367970-G","rs2367970",0,2367970,"intergenic_variant",1,"NR",{"v":5e-70,"d":"5.00E-70"},69.3010299956639,null,0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":6e-70,"d":"6.00E-70"},69.2218487496163,"(EA)",0.475,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":7e-70,"d":"7.00E-70"},69.1549019599857,"(CEP57)",0.89456034,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5175,{"v":9e-70,"d":"9.00E-70"},69.0457574905606,null,0.06308641,"[0.056-0.07] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[8,"rs4564803",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1e-69,"d":"1.00E-69"},69,null,0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":1e-69,"d":"1.00E-69"},69,null,0.121,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.762,{"v":1e-69,"d":"1.00E-69"},69,"(EA)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":2e-69,"d":"2.00E-69"},68.698970004336,null,0.109,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5028,{"v":2e-69,"d":"2.00E-69"},68.698970004336,null,0.06301181,"[0.056-0.07] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC4, APOC4-APOC2, APOC2, CTB-129P6.11","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.3510532,{"v":2e-69,"d":"2.00E-69"},68.698970004336,"(EA, Granulocyte colony-stimulating factor)",0.7496,"[0.67-0.83] unit increase","Affymetrix [509946]","N"]
[19,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.989,{"v":3e-69,"d":"3.00E-69"},68.5228787452803,"(EA)",0.397,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,"NR",{"v":4e-69,"d":"4.00E-69"},68.397940008672,null,0.382,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":6e-69,"d":"6.00E-69"},68.2218487496163,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45394336,"rs71352238","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs71352238-?","rs71352238",0,71352238,"intron_variant",0,"NR",{"v":7e-69,"d":"7.00E-69"},68.1549019599857,null,3.181876,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,0.92,{"v":1e-68,"d":"1.00E-68"},68,"(EA)",0.162,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (mother's attained age)","412,937 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-68,"d":"1.00E-68"},68,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":2e-68,"d":"2.00E-68"},67.698970004336,"(EA)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,"NR",{"v":3E-68,"d":"3.00E-68"},67.5228787452803,null,0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.701,{"v":3E-68,"d":"3.00E-68"},67.5228787452803,"(Hispanic)",0.235,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":3E-68,"d":"3.00E-68"},67.5228787452803,null,0.153,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.695,{"v":1e-67,"d":"1.00E-67"},67,"(Hispanic)",0.233,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21204025,"rs6544366","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","intergenic","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,119492,18160,"rs6544366-T","rs6544366",0,6544366,"intergenic_variant",1,0.2243,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.0549,"[0.049-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[32,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Immature fraction of reticulocytes","170,548 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":2e-67,"d":"2.00E-67"},66.698970004336,null,0.06617714,"[0.059-0.074] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.7,{"v":2e-67,"d":"2.00E-67"},66.698970004336,"(Hispanic)",0.234,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":3e-67,"d":"3.00E-67"},66.5228787452803,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":3e-67,"d":"3.00E-67"},66.5228787452803,"(ICAM2)",0.593,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.231,{"v":6e-67,"d":"6.00E-67"},66.2218487496163,"(Hispanic)",0.275,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-09-05",29455858,"Sung YJ","2018-02-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29455858","A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.","Diastolic blood pressure (cigarette smoking interaction)","80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals","305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals","12q24.12","SH2B3, ATXN2","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,null,{"v":6e-67,"d":"6.00E-67"},66.2218487496163,{"$nulls":3},"Affymetrix, Illumina [18800000] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.785,{"v":8e-67,"d":"8.00E-67"},66.096910013008,"(EA)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.215,{"v":9e-67,"d":"9.00E-67"},66.0457574905606,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":1e-66,"d":"1.00E-66"},66,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.591,{"v":1e-66,"d":"1.00E-66"},66,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":1e-66,"d":"1.00E-66"},66,"(HDL-C.assay, fasting)",3.094,"[NR] unit increase","Illumina [335603]","N"]
[14,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":2E-66,"d":"2.00E-66"},65.698970004336,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,"NR",{"v":3e-66,"d":"3.00E-66"},65.5228787452803,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,"NR",{"v":3e-66,"d":"3.00E-66"},65.5228787452803,null,0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":4e-66,"d":"4.00E-66"},65.397940008672,"(EA)",0.086,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":5e-66,"d":"5.00E-66"},65.3010299956639,null,0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,0.616,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,0.622,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(EA)",0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(FAM3D)",0.581,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.86,{"v":8e-66,"d":"8.00E-66"},65.096910013008,"(Triglycerides in small VLDL)",0.24,"[0.22-0.26] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[14,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,0.615,{"v":1e-65,"d":"1.00E-65"},65,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs4876611",8,116663898,"rs2737252","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","8q23.3","TRPS1","TRPS1",null,null,"ENSG00000104447",null,null,"rs2737252-G","rs2737252",0,2737252,"intron_variant",0,0.715006,{"v":1e-65,"d":"1.00E-65"},65,null,0.0353684,"[0.031-0.039] unit decrease","NR [13737936] (imputed)","N"]
[25,"rs4876611",8,116667634,"rs2737265","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8q23.3",null,"TRPS1",null,null,"ENSG00000104447",null,null,"rs2737265-?","rs2737265",0,2737265,"intron_variant",0,"NR",{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.0381349,"[0.034-0.043] unit decrease","Affymetrix [20259828] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.062,"[NR] unit decrease","NR [NR] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.25,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.07,"[NR] unit decrease","NR [NR] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.105,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.0303,{"v":2e-65,"d":"2.00E-65"},64.698970004336,null,0.1408,"[0.12-0.16] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[25,"rs4876611",8,116663898,"rs2737252","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8q23.3",null,"TRPS1",null,null,"ENSG00000104447",null,null,"rs2737252-?","rs2737252",0,2737252,"intron_variant",0,"NR",{"v":3E-65,"d":"3.00E-65"},64.5228787452803,null,0.0381406,"[0.034-0.043] unit decrease","Affymetrix [20259828] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-T","rs173539",0,173539,"intergenic_variant",1,0.32,{"v":3E-65,"d":"3.00E-65"},64.5228787452803,"(HDL)",0.255,"[0.23-0.28] mmol/l increase","Illumina [NR] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.3,{"v":1e-64,"d":"1.00E-64"},64,null,0.155,"[0.14-0.17] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p13.3","CELSR2, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,null,0.12,"[0.11-0.13] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[35,"rs2072560",11,116639104,"rs10790162","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,0.22,{"v":2e-64,"d":"2.00E-64"},63.698970004336,"(BMI unadjusted)",0.214,"[0.19-0.24] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":2e-64,"d":"2.00E-64"},63.698970004336,null,0.401,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-02-09",29263008,"Guerreiro R","2018-01-01","Lancet Neurol","www.ncbi.nlm.nih.gov/pubmed/29263008","Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.","Dementia with Lewy bodies","1,216 European ancestry cases, 3,791 European ancestry controls","527 European ancestry cases, 663 European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.14,{"v":3e-64,"d":"3.00E-64"},63.5228787452803,null,2.46,"[2.22-2.74]","Illumina [8397716] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(VLDL.small, whole)",4.219,"[NR] unit decrease","Illumina [335603]","N"]
[29,"rs2740488",9,107664301,"rs1883025","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.243,{"v":4e-64,"d":"4.00E-64"},63.397940008672,"(Trans-ethnic initial)",0.0671,"[0.059-0.075] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[19,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,0.989,{"v":5e-64,"d":"5.00E-64"},63.3010299956639,"(EA)",0.372,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":6e-64,"d":"6.00E-64"},63.2218487496163,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.711,{"v":6e-64,"d":"6.00E-64"},63.2218487496163,"(Hispanic)",0.23,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":8e-64,"d":"8.00E-64"},63.096910013008,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs186696265",6,161111700,"rs186696265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,14145,7620,"rs186696265-C","rs186696265",0,186696265,"intergenic_variant",1,"NR",{"v":8e-64,"d":"8.00E-64"},63.096910013008,null,0.359,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs12721028",11,116708413,"rs670","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","APOA1","APOA1-AS, APOA1",null,null,"ENSG00000235910, ENSG00000118137",null,null,"rs670-T","rs670",0,670,"5_prime_UTR_variant",0,0.167,{"v":8e-64,"d":"8.00E-64"},63.096910013008,"(Beta-endorphin, POMC.2558.51.3)",0.54,"[0.48-0.6] unit decrease","Affymetrix [10572788] (imputed)","N"]
[37,"rs4766578",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":1e-63,"d":"1.00E-63"},63,null,0.403,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-C","rs515135",0,515135,"intergenic_variant",1,0.83,{"v":2e-63,"d":"2.00E-63"},62.698970004336,null,0.135,"[0.12-0.15] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.1012,{"v":2e-63,"d":"2.00E-63"},62.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [2501549] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-63,"d":"3.00E-63"},62.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-63,"d":"3.00E-63"},62.5228787452803,"(Mediator of RNA polymerase II transcription subunit 4, MED4.14021.81.3)",0.42,"[0.38-0.46] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":4e-63,"d":"4.00E-63"},62.397940008672,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs184017",19,45396219,"rs157582","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157582-?","rs157582",0,157582,"intron_variant",0,"NR",{"v":4e-63,"d":"4.00E-63"},62.397940008672,null,2.7341528,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-A","rs676210",0,676210,"missense_variant",0,0.2052,{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.0546,"[0.048-0.061] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":5e-63,"d":"5.00E-63"},62.3010299956639,null,0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.733,{"v":7e-63,"d":"7.00E-63"},62.1549019599857,"(Hispanic)",0.244,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,"NR",{"v":9e-63,"d":"9.00E-63"},62.0457574905606,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.69,{"v":1E-62,"d":"1.00E-62"},62,"(Hispanic)",0.222,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-04-12",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Free cholesterol levels in large LDL","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-62,"d":"1.00E-62"},62,null,0.642,"unit decrease","Illumina [15144991] (imputed)","N"]
[50,"rs75627662",19,45416178,"rs483082","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs483082-?","rs483082",0,483082,"non_coding_transcript_exon_variant",0,0.738441,{"v":1E-62,"d":"1.00E-62"},62,null,2.6436493,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Dementia and core Alzheimer's disease neuropathologic changes","up to 3,887 cases, up to 1,027 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2883,{"v":2e-62,"d":"2.00E-62"},61.698970004336,"(Primary)",1.6136,"[1.42-1.8] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-62,"d":"2.00E-62"},61.698970004336,"(S100A13)",0.82494706,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":4e-62,"d":"4.00E-62"},61.397940008672,null,0.3,"[0.24-0.36] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":9e-62,"d":"9.00E-62"},61.0457574905606,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":3e-61,"d":"3.00E-61"},60.5228787452803,"(Free cholesterol in large LDL, conditioned)",0.5335034,"[0.47-0.60] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.709,{"v":5e-61,"d":"5.00E-61"},60.3010299956639,"(Hispanic)",0.226,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":7e-61,"d":"7.00E-61"},60.1549019599857,null,0.099,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":1e-60,"d":"1.00E-60"},60,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18272438,"rs4921914","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,13710,112373,"rs4921914-T","rs4921914",0,4921914,"intergenic_variant",1,0.78,{"v":1e-60,"d":"1.00E-60"},60,"(1-methylxanthine)",0.088,"[0.078-0.098] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19q13.32","APOC2, APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.2,{"v":1e-60,"d":"1.00E-60"},60,null,0.19,"[0.15-0.23] unit increase","Affymetrix [389878]","N"]
[29,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":2e-60,"d":"2.00E-60"},59.698970004336,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111904371,"rs4766578","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-A","rs4766578",0,4766578,"intron_variant",0,0.5028,{"v":2e-60,"d":"2.00E-60"},59.698970004336,null,0.0586027,"[0.052-0.066] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":4e-60,"d":"4.00E-60"},59.397940008672,"(RAC-beta serine/threonine-protein kinase, AKT2.14685.17.3)",0.73,"[0.65-0.81] unit decrease","Affymetrix [10572788] (imputed)","N"]
[14,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,0.592,{"v":6e-60,"d":"6.00E-60"},59.2218487496163,"(EA)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":6e-60,"d":"6.00E-60"},59.2218487496163,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111973358,"rs597808","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs597808-A","rs597808",0,597808,"intron_variant",0,0.47,{"v":8e-60,"d":"8.00E-60"},59.096910013008,"(AA, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.234,{"v":9E-60,"d":"9.00E-60"},59.0457574905606,"(East Asian)",0.274,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.72,{"v":9E-60,"d":"9.00E-60"},59.0457574905606,"(HDL)",0.25,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[5,"rs3832016",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2346,{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.112,"[0.098-0.126] unit decrease","NR [8041861] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":2e-59,"d":"2.00E-59"},58.698970004336,"(TG)",0.17,"[0.14-0.20] mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":2e-59,"d":"2.00E-59"},58.698970004336,"(HDL.large, fasting)",0.703,"[NR] unit increase","Illumina [335603]","N"]
[50,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-59,"d":"2.00E-59"},58.698970004336,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,"NR",{"v":3e-59,"d":"3.00E-59"},58.5228787452803,null,0.085,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","2p23.3",null,"GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":4e-59,"d":"4.00E-59"},58.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs115478735",9,136154867,"rs495828","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,0.28,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(ALP)",0.308,"[0.27-0.35] unit decrease","Illumina [561583]","N"]
[50,"rs1065853",19,45415640,"rs445925","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","19q13.32","APOE, APOC1, APOC2","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.09,{"v":4e-59,"d":"4.00E-59"},58.397940008672,"(BMI unadjusted)",0.568,"[0.5-0.64] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.591,{"v":5e-59,"d":"5.00E-59"},58.3010299956639,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,"NR",{"v":7e-59,"d":"7.00E-59"},58.1549019599857,null,0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-G","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.19,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,null,7.91,"[6.93-8.89] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.952,{"v":9e-59,"d":"9.00E-59"},58.0457574905606,"(Hispanic)",0.574,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs2927482",19,45341948,"rs10407439","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","PVRL2","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,17270,7484,"rs10407439-A","rs10407439",0,10407439,"intergenic_variant",1,0.296,{"v":1E-58,"d":"1.00E-58"},58,null,16.138115,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[8,"rs4564803",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,0.674,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(EA)",0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs449647",19,45408564,"rs449647","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",null,"ENSG00000130203",null,null,447,"rs449647-?","rs449647",0,449647,"regulatory_region_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs449647",19,45408564,"rs449647","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","TOMM40",null,"ENSG00000130203",null,null,447,"rs449647-?","rs449647",0,449647,"regulatory_region_variant",0,"NR",{"v":2e-58,"d":"2.00E-58"},57.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(Cell surface glycoprotein CD200 receptor 2, CD200R1L.8980.19.3)",0.72,"[0.64-0.8] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":2e-58,"d":"2.00E-58"},57.698970004336,"(Apolipoprotein E (isoform E3), APOE.2937.10.2)",0.72,"[0.64-0.8] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","19q13.32","APOC2, APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":3e-58,"d":"3.00E-58"},57.5228787452803,"(L-LDL-FC)",0.75,"[0.65-0.85] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[5,"rs3832016",1,109821511,"rs602633","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","1p13.3","CELSR2, PSRC1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3139,667,"rs602633-T","rs602633",0,602633,"intergenic_variant",1,0.2343,{"v":4e-58,"d":"4.00E-58"},57.397940008672,null,0.0999,"[0.088-0.112] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[23,"rs4921915",8,18259366,"rs721399","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,638,125445,"rs721399-T","rs721399",0,721399,"intergenic_variant",1,0.72,{"v":4e-58,"d":"4.00E-58"},57.397940008672,"(4-acetamidobutanoate)",0.029,"[0.025-0.033] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":5e-58,"d":"5.00E-58"},57.3010299956639,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":6e-58,"d":"6.00E-58"},57.2218487496163,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111865049,"rs7310615","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","SH2B3","SH2B3",null,null,"ENSG00000111252",null,null,"rs7310615-C","rs7310615",0,7310615,"intron_variant",0,0.49,{"v":7e-58,"d":"7.00E-58"},57.1549019599857,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[14,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,0.622,{"v":1e-57,"d":"1.00E-57"},57,"(EA)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","1p13.3","CELSR2, PSRC1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.219,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.124,"[0.11-0.14] unit decrease","Affymetrix [7947838] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":2e-57,"d":"2.00E-57"},56.698970004336,"(EA)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.31,{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,3.47,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-57,"d":"2.00E-57"},56.698970004336,null,0.1052,"[0.092-0.118] unit increase novel","Illumina [6108953] (imputed)","N"]
[14,"rs4704210",5,74637711,"rs10038095","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-A","rs10038095",0,10038095,"intron_variant",0,0.616,{"v":3E-57,"d":"3.00E-57"},56.5228787452803,"(EA)",0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs4803748",19,45251156,"rs2965169","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","BCL3","BCL3",null,null,"ENSG00000069399",null,null,"rs2965169-C","rs2965169",0,2965169,"non_coding_transcript_exon_variant",0,0.3883,{"v":3E-57,"d":"3.00E-57"},56.5228787452803,null,15.944032,"NR z-unit decrease","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-T","rs4299376",0,4299376,"intron_variant",0,0.7278,{"v":4e-57,"d":"4.00E-57"},56.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[14,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,0.615,{"v":4e-57,"d":"4.00E-57"},56.397940008672,"(EA)",0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":6E-57,"d":"6.00E-57"},56.2218487496163,null,4.68,"[4.11-5.25] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs4564803",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1E-56,"d":"1.00E-56"},56,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2014-05-01",24094242,"Li J","2013-10-05","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/24094242","Genome-wide association study on serum alkaline phosphatase levels in a Chinese population.","Serum alkaline phosphatase levels","1,452 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","9q34.2","SURF6, ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-A","rs651007",0,651007,"intergenic_variant",1,0.226,{"v":1E-56,"d":"1.00E-56"},56,null,0.079,"[0.069-0.089] U/L decrease","Affymetrix [658288]","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":1E-56,"d":"1.00E-56"},56,"(EA)",0.105,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs9304381",18,47158234,"rs9304381","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32682,18486,"rs9304381-T","rs9304381",0,9304381,"intergenic_variant",1,0.8098,{"v":1E-56,"d":"1.00E-56"},56,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[50,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,"NR",{"v":1E-56,"d":"1.00E-56"},56,null,0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45415640,"rs445925","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","19q13.32","APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-T","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.11,{"v":1E-56,"d":"1.00E-56"},56,"(activity)",0.071,"[0.049-0.093] ng/ml decrease","Illumina [796174]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.422,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.532,{"v":2e-56,"d":"2.00E-56"},55.698970004336,"(Trans-ethnic initial)",0.0564,"[0.049-0.063] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.226,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(East Asian)",0.269,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.789,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(Trans-ethnic initial)",0.0652,"[0.057-0.074] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.937,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(APOE)",0.795,"[0.7-0.89] unit increase","Illumina [> 1000000] (imputed)","N"]
[50,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.393,{"v":3e-56,"d":"3.00E-56"},55.5228787452803,"(EA)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.987,{"v":5E-56,"d":"5.00E-56"},55.3010299956639,"(EA)",0.413,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-02-05",25898920,"Korostishevsky M","2015-04-22","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/25898920","Genomics and metabolomics of muscular mass in a community-based sample of UK females.","Blood metabolite levels","3,953 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-56,"d":"6.00E-56"},55.2218487496163,"(Mannose levels)",null,null,"Illumina [2300000]","N"]
[8,"rs4564803",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":7e-56,"d":"7.00E-56"},55.1549019599857,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":8e-56,"d":"8.00E-56"},55.096910013008,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-?","rs676210",0,676210,"missense_variant",0,"NR",{"v":9e-56,"d":"9.00E-56"},55.0457574905606,"(VLDL.total, whole)",6.384,"[NR] unit decrease","Illumina [335603]","N"]
[37,"rs4766578",12,111932800,"rs7137828","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Systolic blood pressure","approximately 422,000 European ancestry individuals","NA","12q24.12",null,"ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-?","rs7137828",0,7137828,"intron_variant",0,"NR",{"v":9e-56,"d":"9.00E-56"},55.0457574905606,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0,{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(Trans-ethnic initial)",0.121,"[0.11-0.14] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs7246100",19,45436244,"rs7246099","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,1601,9251,"rs7246099-C","rs7246099",0,7246099,"intergenic_variant",1,0.389,{"v":2E-55,"d":"2.00E-55"},54.698970004336,"(Tubulin-specific chaperone A, TBCA.12501.10.3)",0.44,"[0.38-0.5] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,5.64,"[4.88-6.4] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":3e-55,"d":"3.00E-55"},54.5228787452803,null,0.121,"[NR] unit decrease","NR [NR] (imputed)","N"]
[42,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":3e-55,"d":"3.00E-55"},54.5228787452803,"(HDL-C.by.NMR, fasting)",2.608,"[NR] unit increase","Illumina [335603]","N"]
[32,"rs10793624",10,46001866,"rs11239541","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","10q11.22",null,"2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239541-?","rs11239541",0,11239541,"intron_variant",0,"NR",{"v":7e-55,"d":"7.00E-55"},54.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":8E-55,"d":"8.00E-55"},54.096910013008,null,0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.237,{"v":9e-55,"d":"9.00E-55"},54.0457574905606,"(East Asian)",0.265,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,"NR",{"v":2e-54,"d":"2.00E-54"},53.698970004336,null,0.11,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.9351,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.0881,"[0.077-0.099] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[41,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,"NR",{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.09,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.118,"[NR] unit decrease","NR [NR] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Low density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,null,{"v":3e-54,"d":"3.00E-54"},53.5228787452803,null,0.1615,"[0.14-0.18] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-A","rs1041968",0,1041968,"synonymous_variant",0,0.48,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,null,0.095,"[0.083-0.107] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[22,"rs1692821",8,11705448,"rs1692819","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1692819-A","rs1692819",0,1692819,"intron_variant",0,0.292,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,"(Cathepsin B, CTSB.3061.61.2)",0.42,"[0.36-0.48] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.54,{"v":5e-54,"d":"5.00E-54"},53.3010299956639,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,"NR",{"v":9e-54,"d":"9.00E-54"},53.0457574905606,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.539,{"v":1E-53,"d":"1.00E-53"},53,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-?","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":1E-53,"d":"1.00E-53"},53,"(HDL.mean.size, fasting)",0.084,"[NR] unit increase","Illumina [335603]","N"]
[50,"rs429358",19,45411941,"rs429358","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":1E-53,"d":"1.00E-53"},53,"(females)",3.921738,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-53,"d":"2.00E-53"},52.698970004336,"(APOB.assay, whole)",5.205,"[NR] unit decrease","Illumina [335603]","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.54,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(EA)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,"NR",{"v":3e-53,"d":"3.00E-53"},52.5228787452803,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.12,{"v":3e-53,"d":"3.00E-53"},52.5228787452803,"(LDL-C)",0.48,"[0.42-0.54] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[14,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,"NR",{"v":4e-53,"d":"4.00E-53"},52.397940008672,null,0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723675,"rs1800588","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":4e-53,"d":"4.00E-53"},52.397940008672,null,0.05965,"[0.052-0.067] unit increase novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.399,{"v":6e-53,"d":"6.00E-53"},52.2218487496163,"(glucose/mannose + 54 other traits)",0.101,"[NR] unit increase","Affymetrix, Illumina [534665]","N"]
[29,"rs2740488",9,107664301,"rs1883025","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.25,{"v":6e-53,"d":"6.00E-53"},52.2218487496163,null,0.067,"[NR] unit decrease","NR [NR] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":8e-53,"d":"8.00E-53"},52.096910013008,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":1E-52,"d":"1.00E-52"},52,"(Granulins)",0.7583,"[0.67-0.85] unit decrease","Affymetrix [509946]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Alcohol consumption (drinks per week)","414,343 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.3929,{"v":1E-52,"d":"1.00E-52"},52,null,0.034923363,"[0.03-0.039] unit decrease","Affymetrix [11514936] (imputed)","N"]
[48,"rs56322906",19,11350488,"rs2278426","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","C19orf80","ANGPTL8, DOCK6",null,null,"ENSG00000130173, ENSG00000130158",null,null,"rs2278426-T","rs2278426",0,2278426,"missense_variant",0,0.1249,{"v":1E-52,"d":"1.00E-52"},52,null,0.0756,"[0.066-0.085] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-13",30111768,"Yao C","2018-08-15","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30111768","Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.","Blood protein levels","6861 European ancestry individuals","4298 European ancestry individuals","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.076340503,{"v":1E-52,"d":"1.00E-52"},52,"(APOB)",0.5368132,"unit decrease","Affymetrix, Illumina [8509364] (imputed)","N"]
[8,"rs4564803",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.215,{"v":2E-52,"d":"2.00E-52"},51.698970004336,"(EA)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,0.603,{"v":3E-52,"d":"3.00E-52"},51.5228787452803,"(EA)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs4803748",19,45242740,"rs2927439","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,13425,8222,"rs2927439-A","rs2927439",0,2927439,"intergenic_variant",1,0.638,{"v":3E-52,"d":"3.00E-52"},51.5228787452803,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.08,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[50,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,0.846,{"v":4E-52,"d":"4.00E-52"},51.397940008672,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":4E-52,"d":"4.00E-52"},51.397940008672,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":6E-52,"d":"6.00E-52"},51.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs184017",19,45396219,"rs157582","2015-05-14",22005930,"Hollingworth P","2011-10-18","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/22005930","Genome-wide association study of Alzheimer's disease with psychotic symptoms.","Psychosis and Alzheimer's disease","1,039 European ancestry cases with psychosis, 5,659 European ancestry controls, 260 European, African American and Native American ancestry cases with psychosis from 264 families","NA","19q13.32","APOE","TOMM40",{"$nulls":5},"rs157582-?","rs157582",0,157582,"intron_variant",0,0.26,{"v":9e-52,"d":"9.00E-52"},51.0457574905606,null,2.3,"[NR]","Illumina [1847262] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":1E-51,"d":"1.00E-51"},51,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111784051",19,45389596,"rs7254892","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","NECTIN2, AC011481.2",null,null,"ENSG00000130202, ENSG00000267114",null,null,"rs7254892-A","rs7254892",0,7254892,"intron_variant",0,0.07,{"v":1E-51,"d":"1.00E-51"},51,"(Asian initial, BMI unadjusted)",0.4,"[0.35-0.45] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid AB1-42 levels","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":1E-51,"d":"1.00E-51"},51,null,0.8,"[0.7-0.9] unit decrease","Illumina [8454933] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(EA)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,0.592,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(EA)",0.07,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.785,{"v":2E-51,"d":"2.00E-51"},50.698970004336,"(Trans-ethnic initial)",0.0665,"[0.058-0.075] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.26,"[0.22-0.30] unit decrease","Affymetrix [389878]","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2E-51,"d":"2.00E-51"},50.698970004336,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,null,0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19q13.32","2-APOE, APOC1","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-?","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":3E-51,"d":"3.00E-51"},50.5228787452803,"(APOB.assay, whole)",8.495,"[NR] unit decrease","Illumina [335603]","N"]
[47,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,"NR",{"v":5E-51,"d":"5.00E-51"},50.3010299956639,null,0.247,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723675,"rs1800588","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-?","rs1800588",0,1800588,"intron_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.06402,"[0.056-0.072] unit increase novel","Illumina [6108953] (imputed)","N"]
[47,"rs12608026",18,47119579,"rs11082764","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs11082764-?","rs11082764",0,11082764,"3_prime_UTR_variant",0,"NR",{"v":6E-51,"d":"6.00E-51"},50.2218487496163,null,0.07838,"[0.068-0.089] unit increase novel","Illumina [6108953] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.929,{"v":6E-51,"d":"6.00E-51"},50.2218487496163,"(Trans-ethnic initial)",0.118,"[0.1-0.13] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,0.738,{"v":7e-51,"d":"7.00E-51"},50.1549019599857,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":8e-51,"d":"8.00E-51"},50.096910013008,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,0.785,{"v":8e-51,"d":"8.00E-51"},50.096910013008,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.215,{"v":9e-51,"d":"9.00E-51"},50.0457574905606,"(EA)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs2740488",9,107665739,"rs2575876","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2575876-A","rs2575876",0,2575876,"intron_variant",0,0.2448,{"v":9e-51,"d":"9.00E-51"},50.0457574905606,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.785,{"v":1E-50,"d":"1.00E-50"},50,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":1E-50,"d":"1.00E-50"},50,null,0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2010-07-01",20529992,"Teupser D","2010-06-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20529992","Genetic regulation of serum phytosterol levels and risk of coronary artery disease.","Phytosterol levels","1,495 European ancestry individuals","2,917 European ancestry individuals","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-C","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.322,{"v":2E-50,"d":"2.00E-50"},49.698970004336,"(campesterol)",12,"[NR] % increase","Affymetrix [374370]","N"]
[26,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":2E-50,"d":"2.00E-50"},49.698970004336,null,0.056,"[NR] unit decrease","NR [NR] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-08-22",29860282,"Scelsi MA","2018-05-30","Brain","www.ncbi.nlm.nih.gov/pubmed/29860282","Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.","Cortical amyloid beta load","936 European ancestry individuals","NA","19q13.32","APOE4","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,null,{"v":3e-50,"d":"3.00E-50"},49.5228787452803,"(uncorrected for APOE4 status)",null,null,"Illumina [5137218] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-50,"d":"3.00E-50"},49.5228787452803,null,0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":4E-50,"d":"4.00E-50"},49.397940008672,null,0.0573338,"[0.05-0.065] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":5e-50,"d":"5.00E-50"},49.3010299956639,"(KDR)",0.508,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Total cholesterol levels in LDL","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":5e-50,"d":"5.00E-50"},49.3010299956639,null,0.573,"unit decrease","Illumina [15144991] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2018-01-08",29186428,"Tonjes A","2017-11-27","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/29186428","Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin.","Progranulin levels","1,963 European ancestry individuals, 848 Sorbian (founder/genetic isolate) individuals","1800 European ancestry individuals","1p13.3","CELSR2, PSRC1, MYBPHL, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-C","rs660240",0,660240,"3_prime_UTR_variant",0,0.784,{"v":6e-50,"d":"6.00E-50"},49.2218487496163,null,0.169,"unit increase","Affymetrix [2069113] (imputed)","N"]
[32,"rs10793624",10,45982508,"rs11239537","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular volume","172,433 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239537-C","rs11239537",0,11239537,"intron_variant",0,0.3087,{"v":6e-50,"d":"6.00E-50"},49.2218487496163,null,0.05683413,"[0.049-0.064] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[47,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,"NR",{"v":7e-50,"d":"7.00E-50"},49.1549019599857,null,0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-?","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,{"$nulls":3},"Affymetrix [NR]","N"]
[35,"rs2072560",11,116586283,"rs7350481","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-G","rs7350481",0,7350481,"regulatory_region_variant",1,0.43,{"v":1e-49,"d":"1.00E-49"},49,null,0.241,"[0.21-0.27] unit increase","Illumina [561583]","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs4803748",19,45251156,"rs2965169","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCL3",null,null,"ENSG00000069399",null,null,"rs2965169-?","rs2965169",0,2965169,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-49,"d":"1.00E-49"},49,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.835,{"v":1e-49,"d":"1.00E-49"},49,"(EA)",0.078,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.319,{"v":2e-49,"d":"2.00E-49"},48.698970004336,"(EA)",0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","6q25.3","SLC22A3, LPAL2, LPA, PLG","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.065,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,1.31,"[1.27-1.36]","Affymetrix [9149595] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2019-04-25",30837465,"Wittemans LBL","2019-03-05","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30837465","Assessing the causal association of glycine with risk of cardio-metabolic diseases.","Glycine levels","80,003 European ancestry individuals","NA","8p23.1","LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,0.124,"[0.1-0.14] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":2e-49,"d":"2.00E-49"},48.698970004336,"(EPHA4)",0.492,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[50,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,"NR",{"v":2e-49,"d":"2.00E-49"},48.698970004336,null,0.118,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs35348663",7,73023881,"rs12531645","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL, AC005089.1",null,null,"ENSG00000009950, ENSG00000274080",null,null,"rs12531645-?","rs12531645",0,12531645,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,0.1056,"[0.092-0.12] unit decrease novel","Illumina [6108953] (imputed)","N"]
[29,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,0.748,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs9304381",18,47160953,"rs7241918","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.17,{"v":3E-49,"d":"3.00E-49"},48.5228787452803,null,1.31,"[1.11-1.51] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.785,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(Trans-ethnic initial)",0.062,"[0.053-0.071] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,0.806,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(EA)",0.088,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","HDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.773,{"v":4e-49,"d":"4.00E-49"},48.397940008672,"(Hispanic)",0.243,"[0.21-0.27] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160564476,"rs662138","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-C","rs662138",0,662138,"intron_variant",0,0.83,{"v":5e-49,"d":"5.00E-49"},48.3010299956639,"(isobutyrylcarnitine)",0.077,"[0.067-0.087] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.794,{"v":6E-49,"d":"6.00E-49"},48.2218487496163,"(Hispanic)",0.223,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.06015,"[0.052-0.068] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2954021",8,126495818,"rs10808546","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs10808546-C","rs10808546",0,10808546,"intron_variant",0,0.56,{"v":1e-48,"d":"1.00E-48"},48,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":1e-48,"d":"1.00E-48"},48,null,0.075,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2010-09-13",20694148,"Zabaneh D","2010-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20694148","A genome-wide association study of the metabolic syndrome in Indian Asian men.","Metabolic syndrome","2,554 Indian Asian ancestry individuals","2,240 Indian Asian ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.36,{"v":1e-48,"d":"1.00E-48"},48,"(HDL)",0.07,"[0.06-0.08] mmol/l increase","Illumina [308011]","N"]
[47,"rs77960347",18,47109955,"rs77960347","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.987,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.246,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-48,"d":"2.00E-48"},47.698970004336,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs1692821",8,11710369,"rs1293292","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1293292-G","rs1293292",0,1293292,"intron_variant",0,0.719,{"v":3e-48,"d":"3.00E-48"},47.5228787452803,"(CTSB)",0.395,"[0.34-0.45] unit decrease","Illumina [> 1000000] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,"NR",{"v":3e-48,"d":"3.00E-48"},47.5228787452803,null,0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3e-48,"d":"3.00E-48"},47.5228787452803,"(Il16)",0.7322723,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109821797,"rs4970836","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3425,381,"rs4970836-A","rs4970836",0,4970836,"intergenic_variant",1,0.771,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(Group XIIB secretory phospholipase A2-like protein, PLA2G12B.9380.2.3)",0.42,"[0.36-0.48] unit increase","Affymetrix [10572788] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.828,{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(East Asian)",0.256,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":4e-48,"d":"4.00E-48"},47.397940008672,"(females)",3.2052002,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","11q23.3","APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.84,{"v":6e-48,"d":"6.00E-48"},47.2218487496163,null,0.106,"[NR] unit increase","NR [NR] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","HDL cholesterol","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":6e-48,"d":"6.00E-48"},47.2218487496163,null,0.07,"[0.060-0.080] mmol/L decrease","Illumina [4642479] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.829,{"v":7e-48,"d":"7.00E-48"},47.1549019599857,"(East Asian)",0.254,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":8e-48,"d":"8.00E-48"},47.096910013008,"(females)",3.1868043,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.821,{"v":9e-48,"d":"9.00E-48"},47.0457574905606,"(East Asian)",0.258,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-47,"d":"1.00E-47"},47,null,0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":1e-47,"d":"1.00E-47"},47,"(EA)",0.092,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs6657811",1,109807283,"rs6657811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs6657811-A","rs6657811",0,6657811,"intron_variant",0,0.88,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.109,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.08,"[0.068-0.092] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","2p21","ABCG8, ABCG5","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.3,{"v":2e-47,"d":"2.00E-47"},46.698970004336,null,2.75,"[2.36-3.14] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.933,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.564,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,0.828,{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(East Asian)",0.254,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2012-03-14",22331829,"Chasman DI","2012-02-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22331829","Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.","Response to statins (LDL cholesterol change)","6,989 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":2e-47,"d":"2.00E-47"},46.698970004336,"(baseline LDL-C)",6.2,"[5.42-6.98] mg/dL decrease","Illumina [814418]","N"]
[8,"rs4564803",2,21231524,"rs676210","2013-03-06",23247145,"Makela KM","2012-12-17","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23247145","Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.","LDL (oxidized)","2,080 European ancestry individuals","4,238 European ancestry individuals","2p24.1","apoB","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.77,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,null,10.5,"U/L increase","Illumina [2543887] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.413,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Trans-ethnic initial)",0.0515,"[0.044-0.059] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.412,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18272377,"rs4921913","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,13649,112434,"rs4921913-T","rs4921913",0,4921913,"intergenic_variant",1,0.78,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(4-acetamidobutanoate/N1-methyladenosine)",0.036,"[0.03-0.042] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[47,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(EA)",0.245,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neuritic plaque","up to 4,232 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3155,{"v":3e-47,"d":"3.00E-47"},46.5228787452803,"(Ordinal)",0.9467,"[0.82-1.08] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-04-17",29458411,"Chung J","2018-02-20","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/29458411","Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.","Neuritic plaques or neurofibrillary tangles (pleiotropy)","3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":3e-47,"d":"3.00E-47"},46.5228787452803,{"$nulls":3},"NR [6500000] (imputed)","N"]
[8,"rs4564803",2,21206183,"rs6754295","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,121650,16002,"rs6754295-?","rs6754295",0,6754295,"intergenic_variant",1,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,"(VLDL.small, fasting)",4.127,"[NR] unit decrease","Illumina [335603]","N"]
[21,"rs2126259",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.086,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet distribution width","164,433 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8668,{"v":4e-47,"d":"4.00E-47"},46.397940008672,null,0.07616955,"[0.066-0.087] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,null,1.5,"[1.28-1.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.628,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,"(Hispanic)",0.184,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neurofibrillary tangles","up to 4,707 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3285,{"v":5e-47,"d":"5.00E-47"},46.3010299956639,"(Ordinal I)",0.6632,"[0.57-0.75] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-47,"d":"6.00E-47"},46.2218487496163,"(females)",3.7354689,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.868,{"v":6e-47,"d":"6.00E-47"},46.2218487496163,"(EA)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21982054,"rs1811069","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","22q11.21",null,"UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,3731,324,"rs1811069-?","rs1811069",0,1811069,"intergenic_variant",1,"NR",{"v":6e-47,"d":"6.00E-47"},46.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.4,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.054,"[NR] unit increase","NR [NR] (imputed)","N"]
[48,"rs142158911",19,11190652,"rs142130958","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","19p13.2","LDLR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,550,9386,"rs142130958-A","rs142130958",0,142130958,"intergenic_variant",1,0.11,{"v":7e-47,"d":"7.00E-47"},46.1549019599857,"(Free cholesterol in large LDL)",0.24,"[0.2-0.28] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[49,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":7e-47,"d":"7.00E-47"},46.1549019599857,null,0.108,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.39,{"v":9E-47,"d":"9.00E-47"},46.0457574905606,null,2.84,"[2.45-3.23] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-T","rs651821",0,651821,"5_prime_UTR_variant",0,0.72,{"v":9E-47,"d":"9.00E-47"},46.0457574905606,"(BMI unadjusted)",0.187,"[0.16-0.21] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[14,"rs56912706",5,75003678,"rs2307111","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","5q13.3",null,"POC5",null,null,"ENSG00000152359",null,null,"rs2307111-?","rs2307111",0,2307111,"missense_variant",0,"NR",{"v":1E-46,"d":"1.00E-46"},46,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs115478735",9,136149711,"rs115478735","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO",null,null,"ENSG00000175164",null,null,"rs115478735-T","rs115478735",0,115478735,"intron_variant",0,0.178,{"v":1E-46,"d":"1.00E-46"},46,"(Immunoglobulin superfamily containing leucine-rich repeat protein 2, ISLR2.13124.20.3)",0.45,"[0.39-0.51] unit decrease","Affymetrix [10572788] (imputed)","N"]
[41,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":1E-46,"d":"1.00E-46"},46,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":1E-46,"d":"1.00E-46"},46,"(CRYZL1)",0.7133005,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":2E-46,"d":"2.00E-46"},45.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.249,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(East Asian)",0.238,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.826,{"v":2E-46,"d":"2.00E-46"},45.698970004336,"(East Asian)",0.249,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,"NR",{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs12052200",19,11161537,"rs3786722","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs3786722-C","rs3786722",0,3786722,"intron_variant",0,"NR",{"v":3e-46,"d":"3.00E-46"},45.5228787452803,null,0.074,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,160997118,"rs74617384","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-A","rs74617384",0,74617384,"intron_variant",0,0.942,{"v":4e-46,"d":"4.00E-46"},45.397940008672,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[48,"rs12052200",19,11159096,"rs12052201","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs12052201-G","rs12052201",0,12052201,"intron_variant",0,"NR",{"v":7e-46,"d":"7.00E-46"},45.1549019599857,null,0.075,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (both parents in top 10%)","7,182 cases, 79,767 controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.842,{"v":7e-46,"d":"7.00E-46"},45.1549019599857,null,0.0388,"[0.034-0.044] unit increase","Affymetrix [11535925] (imputed)","N"]
[37,"rs11066320",12,112591686,"rs17630235","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.13","NR","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-G","rs17630235",0,17630235,"intergenic_variant",1,null,{"v":8e-46,"d":"8.00E-46"},45.096910013008,null,0.341,"unit decrease","Affymetrix [at least 2696785] (imputed)","N"]
[8,"rs4564803",2,21225281,"rs1042034","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.22,{"v":1e-45,"d":"1.00E-45"},45,null,5.99,"[5.11-6.87] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[14,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,0.603,{"v":1e-45,"d":"1.00E-45"},45,"(EA)",0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74639259,"rs3843482","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-G","rs3843482",0,3843482,"intron_variant",0,0.38,{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.087,"[0.075-0.099] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.084,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112059557,"rs11065979","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","BRAP","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.45,{"v":2E-45,"d":"2.00E-45"},44.698970004336,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":2E-45,"d":"2.00E-45"},44.698970004336,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs11882123",19,19475088,"rs2965199","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","19p13.11",null,"MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,5524,21547,"rs2965199-?","rs2965199",0,2965199,"intergenic_variant",1,"NR",{"v":3e-45,"d":"3.00E-45"},44.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p21","ABCG8, ABCG5","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.3,{"v":4e-45,"d":"4.00E-45"},44.397940008672,null,3.01,"[2.58-3.44] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[19,"rs6938647",6,160991798,"rs6903649","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs6903649-C","rs6903649",0,6903649,"intron_variant",0,null,{"v":4e-45,"d":"4.00E-45"},44.397940008672,null,2.6,"[1.95-3.25] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-C","rs12916",0,12916,"3_prime_UTR_variant",0,0.39,{"v":5e-45,"d":"5.00E-45"},44.3010299956639,null,2.45,"[2.1-2.8] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,"NR",{"v":5e-45,"d":"5.00E-45"},44.3010299956639,null,0.166,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.762,{"v":6e-45,"d":"6.00E-45"},44.2218487496163,"(EA)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs7970695",12,121424861,"rs7310409","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","12q24.31","C12orf27, HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-G","rs7310409",0,7310409,"intron_variant",0,0.59,{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,6.8,"[5.70-7.80] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[47,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,"NR",{"v":7E-45,"d":"7.00E-45"},44.1549019599857,null,0.066,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":7E-45,"d":"7.00E-45"},44.1549019599857,"(MAP kinase-activated protein kinase 5, MAPKAPK5.8382.47.3)",1.5,"[1.28-1.72] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":8e-45,"d":"8.00E-45"},44.096910013008,null,0.020889835,"[0.018-0.024] unit increase","NR [~ 10000000] (imputed)","N"]
[42,"rs289713",16,57000885,"rs12720922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs12720922-G","rs12720922",0,12720922,"intron_variant",0,0.793,{"v":8e-45,"d":"8.00E-45"},44.096910013008,"(Hispanic)",0.214,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":9e-45,"d":"9.00E-45"},44.0457574905606,null,0.05407684,"[0.047-0.062] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-03-15",23263486,"Kottgen A","2012-12-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23263486","Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.","Urate levels","49,825 European ancestry males, 60,522 European ancestry females","Up to 32,813 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":1e-44,"d":"1.00E-44"},44,null,0.074,"[0.063-0.084] mg/dl increase","Affymetrix, Illumina, Perlegen [2450547] (imputed)","N"]
[32,"rs10793624",10,45982508,"rs11239537","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239537-C","rs11239537",0,11239537,"intron_variant",0,0.3088,{"v":1e-44,"d":"1.00E-44"},44,null,0.0538346,"[0.046-0.061] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2013-12-03",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","HDL cholesterol","7,917 African American individuals, 3,506 Hispanic individuals","7,138 African American individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-A","rs247617",0,247617,"regulatory_region_variant",1,0.262,{"v":1e-44,"d":"1.00E-44"},44,"(AA)",0.0619,"[NR] unit increase","Affymetrix [NR]","N"]
[47,"rs9304381",18,47160953,"rs7241918","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,0.19,{"v":1e-44,"d":"1.00E-44"},44,null,0.09,"[NR] unit decrease","NR [NR] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-44,"d":"1.00E-44"},44,null,0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.01,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.47,"[0.41-0.53] unit decrease","Affymetrix [389878]","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,0.672,{"v":2e-44,"d":"2.00E-44"},43.698970004336,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1235162",6,29206683,"rs3130820","2018-12-17",29483656,"Pardinas AF","2018-02-26","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29483656","Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.","Schizophrenia","40,675 European ancestry cases, 64,643 European ancestry controls","1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls","6p22.1","xMHC","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130820-?","rs3130820",0,3130820,"intron_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,1.281,"[1.25-1.32]","Illumina [8000000] (imputed)","N"]
[35,"rs180327",11,116624703,"rs180326","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Triglyceride levels","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs180326-C","rs180326",0,180326,"intron_variant",0,0.22,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.06,"[0.05-0.06] unit increase","Illumina [4642479] (imputed)","N"]
[35,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2018-04-26",25751624,"Onengut-Gumuscu S","2015-04-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25751624","Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.","Type 1 diabetes","6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios","NA","12q24.12","SH2B3","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-C","rs653178",0,653178,"intron_variant",0,0.48,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,1.3,null,"Illumina [135870]","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0793,{"v":2e-44,"d":"2.00E-44"},43.698970004336,null,0.08988161,"[0.077-0.102] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2009-09-28",17998437,"Li H","2007-11-12","Arch Neurol","www.ncbi.nlm.nih.gov/pubmed/17998437","Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.","Alzheimer's disease","753 European ancestry cases, 736 European ancestry controls","418 European ancestry cases, 249 European ancestry controls","19q13.32","APOE, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-44,"d":"2.00E-44"},43.698970004336,{"$nulls":3},"Affymetrix [469438]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.601,{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.0187927,"[0.016-0.021] unit increase","NR [~ 9732723] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2126259",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","11q23.3",null,"ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-44,"d":"3.00E-44"},43.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":4e-44,"d":"4.00E-44"},43.397940008672,"(Insulin receptor)",0.6958,"[0.6-0.79] unit decrease","Affymetrix [509946]","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.328,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(EA)",0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs5072",11,116703640,"rs5128","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","11q23.3","NR","APOC3",null,null,"ENSG00000110245",null,null,"rs5128-C","rs5128",0,5128,"3_prime_UTR_variant",0,0.916,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(Beta-endorphin, POMC.2558.51.3)",0.6,"[0.52-0.68] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Neurofibrillary tangles","up to 4,707 individuals","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.3219,{"v":5e-44,"d":"5.00E-44"},43.3010299956639,"(Ordinal II)",0.7871,"[0.68-0.9] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,"NR",{"v":6e-44,"d":"6.00E-44"},43.2218487496163,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,"NR",{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2015-06-08",25350695,"Postmus I","2014-10-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25350695","Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.","Response to statins (LDL cholesterol change)","18,596 European ancestry individuals","23,279 European ancestry individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.087,{"v":7e-44,"d":"7.00E-44"},43.1549019599857,null,0.052,"[0.044-0.060] unit increase","Affymetrix, Illumina, Perlegen [at least 2500000] (imputed)","N"]
[50,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":7e-44,"d":"7.00E-44"},43.1549019599857,"(Valine--tRNA ligase, VARS.13083.18.3)",1.48,"[1.26-1.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-43,"d":"1.00E-43"},43,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2126259",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs62568184",9,107657070,"rs3905000","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-G","rs3905000",0,3905000,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.786,{"v":1e-43,"d":"1.00E-43"},43,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.055,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Monocyte count","170,721 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5169,{"v":1e-43,"d":"1.00E-43"},43,null,0.04937698,"[0.042-0.056] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs4803748",19,45242740,"rs2927439","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,13425,8222,"rs2927439-A","rs2927439",0,2927439,"intergenic_variant",1,"NR",{"v":1e-43,"d":"1.00E-43"},43,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63105538,"rs12047226","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs12047226-T","rs12047226",0,12047226,"intron_variant",0,0.678,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs6882345",5,156390297,"rs6882076","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.334,{"v":2e-43,"d":"2.00E-43"},42.698970004336,"(Trans-ethnic initial)",0.0508,"[0.044-0.058] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red blood cell count","172,952 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5174,{"v":2e-43,"d":"2.00E-43"},42.698970004336,null,0.04902019,"[0.042-0.056] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-C","rs1748195",0,1748195,"intron_variant",0,"NR",{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74637711,"rs10038095","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","5q13.3","HMGCR","HMGCR",null,null,"ENSG00000113161",null,null,"rs10038095-T","rs10038095",0,10038095,"intron_variant",0,0.38,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,0.083,"[0.071-0.095] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[35,"rs2000571",11,116581641,"rs2367970","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,52673,37245,"rs2367970-G","rs2367970",0,2367970,"intergenic_variant",1,0.789,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,"(EA)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.392,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,"(East Asian)",0.201,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","19q13.32","APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":3E-43,"d":"3.00E-43"},42.5228787452803,null,6.61,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,"NR",{"v":4e-43,"d":"4.00E-43"},42.397940008672,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-43,"d":"4.00E-43"},42.397940008672,"(Cofilin-1, CFL1.4203.50.2)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,0.786,{"v":5e-43,"d":"5.00E-43"},42.3010299956639,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-43,"d":"6.00E-43"},42.2218487496163,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs62568184",9,107648595,"rs3847302","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3847302-A","rs3847302",0,3847302,"intron_variant",0,"NR",{"v":6e-43,"d":"6.00E-43"},42.2218487496163,null,0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.761,{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,null,0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58678512,"rs10468017","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-?","rs10468017",0,10468017,"intron_variant",0,"NR",{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(levels)",0,"[0.80-4.70] % increase","Illumina [NR] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.35,{"v":7e-43,"d":"7.00E-43"},42.1549019599857,"(Indian)",3.18,"[2.73-3.63] unit increase","Illumina [551825]","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.674,{"v":8e-43,"d":"8.00E-43"},42.096910013008,"(EA)",0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":9e-43,"d":"9.00E-43"},42.0457574905606,null,4.94,"[4.16-5.72] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[21,"rs2126259",8,9184231,"rs4240624","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-A","rs4240624",0,4240624,"intron_variant",0,0.925,{"v":1E-42,"d":"1.00E-42"},42,"(Trans-ethnic initial)",0.0818,"[0.07-0.093] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,"NR",{"v":1E-42,"d":"1.00E-42"},42,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs12052200",19,11161537,"rs3786722","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs3786722-C","rs3786722",0,3786722,"intron_variant",0,0.754,{"v":1E-42,"d":"1.00E-42"},42,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.061,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","1p13.3","CELSR2, PSRC1, SORT1","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.21,{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.23,"[0.19-0.27] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-42,"d":"2.00E-42"},41.698970004336,"(EA)",1.4285715,null,"Illumina [12023830] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.39,{"v":3e-42,"d":"3.00E-42"},41.5228787452803,null,0.051,"[NR] unit increase","NR [NR] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,0.806,{"v":3e-42,"d":"3.00E-42"},41.5228787452803,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-42,"d":"3.00E-42"},41.5228787452803,null,0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.399,{"v":4e-42,"d":"4.00E-42"},41.397940008672,"(East Asian)",0.197,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58727325,"rs261332","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-?","rs261332",0,261332,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-42,"d":"4.00E-42"},41.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[48,"rs12052200",19,11159096,"rs12052201","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs12052201-G","rs12052201",0,12052201,"intron_variant",0,0.754,{"v":4e-42,"d":"4.00E-42"},41.397940008672,"(EA)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21237544,"rs673548","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs673548-?","rs673548",0,673548,"intron_variant",0,"NR",{"v":5E-42,"d":"5.00E-42"},41.3010299956639,"(VLDL.total, fasting)",6.624,"[NR] unit decrease","Illumina [335603]","N"]
[50,"rs75627662",19,45413576,"rs75627662","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-?","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-42,"d":"6.00E-42"},41.2218487496163,null,0.09071,"[0.078-0.104] unit increase novel","Illumina [6108953] (imputed)","N"]
[50,"rs1065853",19,45415640,"rs445925","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","19q13.32","APOEC1, APOEC2, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-?","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.06,{"v":6e-42,"d":"6.00E-42"},41.2218487496163,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid AB1-42 levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":6e-42,"d":"6.00E-42"},41.2218487496163,{"$nulls":3},"Illumina [563980]","N"]
[26,"rs2954021",8,126482077,"rs2954021","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":7e-42,"d":"7.00E-42"},41.1549019599857,null,0.05782,"[0.049-0.066] unit decrease novel","Illumina [6108953] (imputed)","N"]
[15,"rs6882345",5,156392248,"rs12517431","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q33.3","intergenic","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,1982,64176,"rs12517431-T","rs12517431",0,12517431,"intergenic_variant",1,0.6045,{"v":8e-42,"d":"8.00E-42"},41.096910013008,null,0.0365,"[0.031-0.042] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[49,"rs73001020",19,19394368,"rs138295924","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.11","SUGP1","SUGP1",null,null,"ENSG00000105705",null,null,"rs138295924-A","rs138295924",0,138295924,"intron_variant",0,0.9553,{"v":8e-42,"d":"8.00E-42"},41.096910013008,null,0.098,"[0.084-0.112] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs33924196",8,126507389,"rs2954038","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-A","rs2954038",0,2954038,"intron_variant",0,0.7182,{"v":1E-41,"d":"1.00E-41"},41,null,0.041,"[0.035-0.047] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.35,{"v":1E-41,"d":"1.00E-41"},41,"(Hispanic)",0.188,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,0.964,{"v":1E-41,"d":"1.00E-41"},41,"(EA)",0.167,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.4253,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,6.8761177,"[5.88-7.88] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.082,"[NR] unit decrease","NR [NR] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.063,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2010-03-15",20167578,"Barbalic M","2010-02-18","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20167578","Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels.","Soluble levels of adhesion molecules","Up to 9,813 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(P-Selectin)",14,"[12.04-15.96] % increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs9411489","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs9411489-T","rs9411489",1,635634,"regulatory_region_variant",1,0.21,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.077,"[NR] unit increase","NR [NR] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.857,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(East Asian)",0.267,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-G","rs821840",0,821840,"regulatory_region_variant",1,0.168,{"v":2E-41,"d":"2.00E-41"},40.698970004336,null,0.0656,"[0.056-0.075] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2E-41,"d":"2.00E-41"},40.698970004336,"(PSME1)",0.66324866,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":3e-41,"d":"3.00E-41"},40.5228787452803,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,"NR",{"v":4E-41,"d":"4.00E-41"},40.397940008672,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.9351,{"v":4E-41,"d":"4.00E-41"},40.397940008672,null,0.0762,"[0.065-0.087] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,2.6,"[2.21-2.99] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[15,"rs6882345",5,156390297,"rs6882076","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.36,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.051,"[NR] unit decrease","NR [NR] (imputed)","N"]
[35,"rs11604424",11,116657561,"rs3741298","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs3741298-C","rs3741298",0,3741298,"intron_variant",0,0.203,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,"(EA)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.117,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.136,"[0.12-0.16] unit decrease","Affymetrix [7947838] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1167,{"v":5e-41,"d":"5.00E-41"},40.3010299956639,null,0.1359,"[0.12-0.16] unit decrease","NR [8041861] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-A","rs10455872",0,10455872,"intron_variant",0,0.933,{"v":6e-41,"d":"6.00E-41"},40.2218487496163,"(EA)",0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":7e-41,"d":"7.00E-41"},40.1549019599857,null,0.101,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":8E-41,"d":"8.00E-41"},40.096910013008,"(Furin, FURIN.6276.16.3)",0.34,"[0.28-0.4] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum albumin level","102,223 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.05949,"[0.051-0.068] unit decrease","Illumina [6108953] (imputed)","N"]
[20,"rs34121855",7,72999105,"rs9638182","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","7q11.23","MLXIPL","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.81,{"v":1e-40,"d":"1.00E-40"},40,null,0.1,"[0.084-0.116] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.122,{"v":1e-40,"d":"1.00E-40"},40,"(Hispanic)",0.278,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs9304381",18,47158186,"rs10438978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,32634,18534,"rs10438978-T","rs10438978",0,10438978,"intergenic_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.059,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs9304381",18,47160953,"rs7241918","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,35401,15767,"rs7241918-G","rs7241918",0,7241918,"intergenic_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs9304381",18,47164717,"rs7239867","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,39165,12003,"rs7239867-A","rs7239867",0,7239867,"TF_binding_site_variant",1,"NR",{"v":1e-40,"d":"1.00E-40"},40,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2009-02-25",19125160,"Feulner TM","2009-01-07","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/19125160","Examination of the current top candidate genes for AD in a genome-wide association study.","Alzheimer's disease","491 European ancestry cases, 479 European ancestry controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":1e-40,"d":"1.00E-40"},40,{"$nulls":3},"Illumina [~ 550000]","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,"NR",{"v":2e-40,"d":"2.00E-40"},39.698970004336,null,0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18273300,"rs1495743","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14572,111511,"rs1495743-G","rs1495743",0,1495743,"intergenic_variant",1,0.188,{"v":2e-40,"d":"2.00E-40"},39.698970004336,"(SM-7 + 11 other traits)",0.256,"[NR] unit decrease","Affymetrix, Illumina [534665]","N"]
[50,"rs157592",19,45422946,"rs4420638","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","19q13.32","APOC2, APOE, APOC4, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":2e-40,"d":"2.00E-40"},39.698970004336,null,0.06,"[0.05-0.07] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72877166,"rs2074755","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2074755-?","rs2074755",0,2074755,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-40,"d":"3.00E-40"},39.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":3e-40,"d":"3.00E-40"},39.5228787452803,"(Intercellular adhesion molecule 5, ICAM5.8245.27.3)",0.42,"[0.36-0.48] unit decrease","Affymetrix [10572788] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":4e-40,"d":"4.00E-40"},39.397940008672,null,0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2015-05-23",21300955,"Dehghan A","2011-02-07","Circulation","www.ncbi.nlm.nih.gov/pubmed/21300955","Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.","C-reactive protein levels","63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals","16,540 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-40,"d":"5.00E-40"},39.3010299956639,null,0.072,"[0.06-0.08] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":5e-40,"d":"5.00E-40"},39.3010299956639,"(ICAM5)",0.457,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-04-17",29458411,"Chung J","2018-02-20","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/29458411","Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.","Neuritic plaques or cerebral amyloid angiopathy (pleiotropy)","3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":5e-40,"d":"5.00E-40"},39.3010299956639,{"$nulls":3},"NR [6500000] (imputed)","N"]
[37,"rs11066320",12,112273499,"rs11513729","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","MAPKAPK5-AS1","ALDH2 - MAPKAPK5-AS1","ENSG00000111275","ENSG00000234608",null,18166,4069,"rs11513729-T","rs11513729",0,11513729,"intergenic_variant",1,0.4,{"v":8e-40,"d":"8.00E-40"},39.096910013008,"(AA, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"NR [2501543] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.499,{"v":1e-39,"d":"1.00E-39"},39,"(EA)",0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","11p11.2",null,"CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.355,{"v":1e-39,"d":"1.00E-39"},39,"(Hispanic)",0.185,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,57005479,"rs1532624","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-?","rs1532624",0,1532624,"intron_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,"(APOA1.assay, fasting)",3.92,"[NR] unit increase","Illumina [335603]","N"]
[47,"rs77960347",18,47109955,"rs77960347","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs77960347-A","rs77960347",0,77960347,"missense_variant",0,0.9878,{"v":1e-39,"d":"1.00E-39"},39,null,0.1674,"[0.14-0.19] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,"(females)",3.1072497,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":1e-39,"d":"1.00E-39"},39,null,0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-39,"d":"1.00E-39"},39,"(Cytoskeleton-associated protein 2, CKAP2.5345.51.3)",0.6,"[0.5-0.7] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2008-09-08",17474819,"Coon KD","2007-04-01","J Clin Psychiatry","www.ncbi.nlm.nih.gov/pubmed/17474819","A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.","Alzheimer's disease (late onset)","664 European ancestry cases, 422 European ancestry controls","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-39,"d":"1.00E-39"},39,null,4.01,"[NR]","Affymetrix [~ 502627]","N"]
[50,"rs157592",19,45422946,"rs4420638","2008-09-15",17975299,"Webster JA","2007-11-01","Neurodegener Dis","www.ncbi.nlm.nih.gov/pubmed/17975299","Sorl1 as an Alzheimer's disease predisposition gene?","Alzheimer's disease","664 cases, 422 controls","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":1e-39,"d":"1.00E-39"},39,{"$nulls":3},"Affymetrix [~ 502627]","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":2e-39,"d":"2.00E-39"},38.698970004336,null,0.151,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-G","rs4299376",0,4299376,"intron_variant",0,0.319,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.215,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(EA)",0.073,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.115,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(Hispanic)",0.281,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.586,{"v":2e-39,"d":"2.00E-39"},38.698970004336,"(Asian initial, BMI unadjusted)",0.133,"[0.11-0.15] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.274,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,"(East Asian)",0.196,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.08,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,null,0.16,"[0.14-0.18] unit decrease","Affymetrix [7947838] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0799,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,null,0.1603,"[0.14-0.18] unit decrease","NR [8041861] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":3e-39,"d":"3.00E-39"},38.5228787452803,"(Endothelial monocyte-activating polypeptide 2, AIMP1.2714.78.2)",0.33,"[0.27-0.39] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.17646,{"v":4e-39,"d":"4.00E-39"},38.397940008672,null,7.44,"[6.32-8.56] (nmol/min/ml) decrease","Affymetrix, Illumina [13572687] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":4e-39,"d":"4.00E-39"},38.397940008672,"(APOB.assay, fasting)",5.251,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs964184",11,116648917,"rs964184","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","11q23.3","APO-cluster","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":4e-39,"d":"4.00E-39"},38.397940008672,null,0.118,"[0.1-0.14] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[37,"rs11066320",12,112200150,"rs2013002","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ALDH2","AC002996.1",null,null,"ENSG00000257767",null,null,"rs2013002-T","rs2013002",0,2013002,"intron_variant",0,0.44,{"v":4e-39,"d":"4.00E-39"},38.397940008672,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[19,"rs55730499",6,161005610,"rs55730499","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","6q25.3","SLC22A3, LPAL2, LPA","LPA",null,null,"ENSG00000198670",null,null,"rs55730499-T","rs55730499",0,55730499,"intron_variant",0,0.056243,{"v":5e-39,"d":"5.00E-39"},38.3010299956639,null,1.37,"[1.31- 1.44]","Affymetrix, Illumina [8600000] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2011-09-30",21900290,"Qi Q","2011-09-06","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/21900290","Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes.","Lp (a) levels","1,450 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-G","rs10455872",0,10455872,"intron_variant",0,0.07,{"v":5e-39,"d":"5.00E-39"},38.3010299956639,null,1.28,"[1.08-1.48] mg/dL increase","Illumina [~ 2500000] (imputed)","N"]
[37,"rs11066320",12,112684221,"rs7953257","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.13","HECTD4","HECTD4",null,null,"ENSG00000173064",null,null,"rs7953257-A","rs7953257",0,7953257,"intron_variant",0,0.4,{"v":5e-39,"d":"5.00E-39"},38.3010299956639,"(AA, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[50,"rs395908",19,45376284,"rs519113","2013-07-12",23565137,"Miyashita A","2013-04-02","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23565137","SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.","Alzheimer's disease (late onset)","891 Japanese ancestry cases, 844 Japanese ancestry controls","1,224 East Asian ancestry cases, 2,114 East Asian ancestry controls, 11,840 European ancestry cases, 10,931 European ancestry controls","19q13.32","APOE, CEACAM16, BCL3, PVRL2, TOMM40, PPP1R37","NECTIN2",null,null,"ENSG00000130202",null,null,"rs519113-G","rs519113",0,519113,"intron_variant",0,0.29,{"v":5e-39,"d":"5.00E-39"},38.3010299956639,"(Japanese)",2.09,"[1.87-2.34]","Affymetrix [5877918] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,0.053,"[0.045-0.061] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[42,"rs1864163",16,56997233,"rs1864163","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1864163-G","rs1864163",0,1864163,"intron_variant",0,0.8,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,null,4.12,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":7E-39,"d":"7.00E-39"},38.1549019599857,"(Histone-lysine N-methyltransferase 2C, KMT2C.11402.17.3)",0.59,"[0.49-0.69] unit increase","Affymetrix [10572788] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.6,{"v":1e-38,"d":"1.00E-38"},38,null,0.08,"[0.068-0.092] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[35,"rs758044300",11,116574336,"rs1145198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,45368,44550,"rs1145198-G","rs1145198",0,1145198,"TF_binding_site_variant",1,"NR",{"v":1e-38,"d":"1.00E-38"},38,null,0.058,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,"NR",{"v":1e-38,"d":"1.00E-38"},38,null,0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-38,"d":"1.00E-38"},38,"(Protocadherin beta-10, PCDHB10.9963.19.3)",0.59,"[0.49-0.69] unit decrease","Affymetrix [10572788] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2011-09-21",21829393,"Plagnol V","2011-08-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21829393","Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.","Type 1 diabetes","8,506 European ancestry cases, up to 10,596 European ancestry controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":2e-38,"d":"2.00E-38"},37.698970004336,null,1.3,"[NR]","Affymetrix, Illumina [NR]","N"]
[31,"rs117488242",10,5256272,"rs17134585","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite ratios","Up to 5,591 European ancestry individuals","Up to 1,767 European ancestry individuals","10p15.1","AKR1C4","AKR1C4",null,null,"ENSG00000198610",null,null,"rs17134585-T","rs17134585",0,17134585,"intron_variant",0,0.84,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,"(androsterone sulfate/epiandrosterone sulfate)",0.043,"[0.037-0.049] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,null,4.74,"[3.92-5.56] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2015-07-28",25188341,"Beecham GW","2014-09-04","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/25188341","Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.","Dementia and core Alzheimer's disease neuropathologic changes","up to 3,887 cases, up to 1,027 controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.2864,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,"(Complete)",1.501,"[1.27-1.73] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":3e-38,"d":"3.00E-38"},37.5228787452803,null,0.08416118,"[0.071-0.097] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[29,"rs2740488",9,107665739,"rs2575876","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2575876-?","rs2575876",0,2575876,"intron_variant",0,"NR",{"v":4e-38,"d":"4.00E-38"},37.397940008672,null,0.05618,"[0.048-0.065] unit decrease novel","Illumina [6108953] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Immature fraction of reticulocytes","170,548 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.0792,{"v":4e-38,"d":"4.00E-38"},37.397940008672,null,0.08313494,"[0.071-0.096] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[15,"rs6882345",5,156394441,"rs9715911","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q33.3","intergenic","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,4175,61983,"rs9715911-A","rs9715911",0,9715911,"intergenic_variant",1,0.6039,{"v":5e-38,"d":"5.00E-38"},37.3010299956639,null,0.035,"[0.03-0.04] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2010-02-28",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Fasting blood glucose","46,186 European ancestry individuals","76,558 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":6e-38,"d":"6.00E-38"},37.2218487496163,null,0.029,"[0.023-0.035] mmol/L increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[50,"rs142042446",19,45394336,"rs71352238","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs71352238-?","rs71352238",0,71352238,"intron_variant",0,"NR",{"v":6e-38,"d":"6.00E-38"},37.2218487496163,"(females)",3.0343766,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.925,{"v":7e-38,"d":"7.00E-38"},37.1549019599857,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,0.62,{"v":8e-38,"d":"8.00E-38"},37.096910013008,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,"NR",{"v":8e-38,"d":"8.00E-38"},37.096910013008,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs35717353",15,58577777,"rs12903590","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12903590-?","rs12903590",0,12903590,"intron_variant",0,"NR",{"v":9e-38,"d":"9.00E-38"},37.0457574905606,null,0.06743,"[0.057-0.078] unit increase novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,"(TG.assay, whole)",0.07,"[NR] unit increase","Illumina [335603]","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.072,{"v":1e-37,"d":"1.00E-37"},37,"(EA)",0.093,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112684221,"rs7953257","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.13","HECTD4","HECTD4",null,null,"ENSG00000173064",null,null,"rs7953257-A","rs7953257",0,7953257,"intron_variant",0,0.44,{"v":1e-37,"d":"1.00E-37"},37,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[41,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,"NR",{"v":1e-37,"d":"1.00E-37"},37,null,0.063,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","19q13.32","2-APOE, APOC1","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-?","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":1e-37,"d":"1.00E-37"},37,"(LDL-C.assay, whole)",9.284,"[NR] unit decrease","Illumina [335603]","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3E-37,"d":"3.00E-37"},36.5228787452803,"(VIMP)",0.62421465,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[21,"rs12546198",8,9219887,"rs34597048","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","8p23.1",null,"AC022784.1",null,null,"ENSG00000248538",null,null,"rs34597048-?","rs34597048",0,34597048,"intron_variant",0,"NR",{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.0455021,"[0.038-0.053] unit decrease","Affymetrix [20259828] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":5e-37,"d":"5.00E-37"},36.3010299956639,null,0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1e-36,"d":"1.00E-36"},36,"(FLT4)",0.442,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[48,"rs12052200",19,11161537,"rs3786722","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs3786722-C","rs3786722",0,3786722,"intron_variant",0,"NR",{"v":1e-36,"d":"1.00E-36"},36,null,0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,"NR",{"v":2e-36,"d":"2.00E-36"},35.698970004336,null,0.057,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":2e-36,"d":"2.00E-36"},35.698970004336,"(Amyloid beta A4 precursor protein-binding family B member 2, APBB2.12753.6.3)",0.57,"[0.47-0.67] unit increase","Affymetrix [10572788] (imputed)","N"]
[35,"rs11820589",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,"NR",{"v":3e-36,"d":"3.00E-36"},35.5228787452803,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,0.674,{"v":3e-36,"d":"3.00E-36"},35.5228787452803,"(EA)",0.062,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.46,{"v":5E-36,"d":"5.00E-36"},35.3010299956639,null,2.3,"[1.93-2.67] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":5E-36,"d":"5.00E-36"},35.3010299956639,null,0.062,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","20q13.12","NR","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.0337,{"v":6e-36,"d":"6.00E-36"},35.2218487496163,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[14,"rs253412",5,74971846,"rs34361","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","POC5",null,null,"ENSG00000152359",null,null,"rs34361-A","rs34361",0,34361,"intron_variant",0,"NR",{"v":9e-36,"d":"9.00E-36"},35.0457574905606,null,0.055,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":1E-35,"d":"1.00E-35"},35,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19329924,"rs2228603","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2228603-T","rs2228603",0,2228603,"missense_variant",0,"NR",{"v":1E-35,"d":"1.00E-35"},35,{"$nulls":3},"NR [2501549] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":2E-35,"d":"2.00E-35"},34.698970004336,"(EA)",0.083,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58727325,"rs261332","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","15q21.3","NR","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-?","rs261332",0,261332,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-35,"d":"2.00E-35"},34.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","19q13.32","APOC1, APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.079,{"v":2E-35,"d":"2.00E-35"},34.698970004336,null,0.1368,"[0.12-0.16] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-35,"d":"3.00E-35"},34.5228787452803,"(TG.by.NMR, whole)",0.052,"[NR] unit increase","Illumina [335603]","N"]
[9,"rs1728918",2,27635463,"rs1728918","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p23.3","NR","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-?","rs1728918",0,1728918,"regulatory_region_variant",1,"NR",{"v":5e-35,"d":"5.00E-35"},34.3010299956639,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":6e-35,"d":"6.00E-35"},34.2218487496163,"(Selenoprotein S, VIMP.11286.78.3)",0.41,"[0.35-0.47] unit increase","Affymetrix [10572788] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,0.675,{"v":1e-34,"d":"1.00E-34"},34,"(EA)",0.06,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.0752,{"v":1e-34,"d":"1.00E-34"},34,"(Trans-ethnic initial)",0.0842,"[0.072-0.097] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1, APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.078,{"v":1e-34,"d":"1.00E-34"},34,"(Uncharacterized protein C14orf93, C14orf93.6439.59.3)",0.56,"[0.46-0.66] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-34,"d":"2.00E-34"},33.698970004336,"(HBQ1)",0.60210574,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[35,"rs11600380",11,116617240,"rs11216126","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","11q23.3","intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,88272,1646,"rs11216126-C","rs11216126",0,11216126,"intergenic_variant",1,0.2,{"v":3E-34,"d":"3.00E-34"},33.5228787452803,null,0.0322,"[0.027-0.037] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","12q24.12",null,"SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":3E-34,"d":"3.00E-34"},33.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.814,{"v":6E-34,"d":"6.00E-34"},33.2218487496163,"(Trans-ethnic initial)",0.0669,"[0.054-0.08] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","9q34.2",null,"ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":8e-34,"d":"8.00E-34"},33.096910013008,null,0.0311795,"[0.026-0.036] unit increase","Affymetrix [20259828] (imputed)","N"]
[15,"rs6882345",5,156390297,"rs6882076","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.334,{"v":1e-33,"d":"1.00E-33"},33,"(Trans-ethnic initial)",0.0456,"[0.038-0.053] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[21,"rs2126259",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":1e-33,"d":"1.00E-33"},33,"(EA)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049551,"rs11207995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs11207995-A","rs11207995",0,11207995,"intron_variant",0,0.674,{"v":2e-33,"d":"2.00E-33"},32.698970004336,"(EA)",0.059,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.526,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,"(EA)",0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112486818,"rs17696736","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.13","NAA25","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,0.56,{"v":3e-33,"d":"3.00E-33"},32.5228787452803,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[40,"rs6602911",13,114544024,"rs7140110","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","13q34",null,"GAS6-AS1, GAS6",null,null,"ENSG00000233695, ENSG00000183087",null,null,"rs7140110-?","rs7140110",0,7140110,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-33,"d":"3.00E-33"},32.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":5e-33,"d":"5.00E-33"},32.3010299956639,"(EA)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs11887534",2,44075483,"rs76866386","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs76866386-T","rs76866386",0,76866386,"non_coding_transcript_exon_variant",0,0.93,{"v":6e-33,"d":"6.00E-33"},32.2218487496163,null,0.139,"[0.12-0.16] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[29,"rs2740488",9,107665739,"rs2575876","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2575876-A","rs2575876",0,2575876,"intron_variant",0,0.25,{"v":1e-32,"d":"1.00E-32"},32,null,0.0371,"[0.031-0.043] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[42,"rs193695",16,56985139,"rs9989419","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-G","rs9989419",0,9989419,"regulatory_region_variant",1,0.6,{"v":1e-32,"d":"1.00E-32"},32,null,0.04,"[0.03-0.05] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[22,"rs11250098",8,11078949,"rs2409749","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","intergenic","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,17769,26186,"rs2409749-A","rs2409749",0,2409749,"regulatory_region_variant",1,0.51151,{"v":2e-32,"d":"2.00E-32"},31.698970004336,null,11.865,"z score increase","Illumina [18485882] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.181,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(Trans-ethnic initial)",0.0555,"[0.046-0.065] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.832,{"v":2e-32,"d":"2.00E-32"},31.698970004336,"(EA)",0.068,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","LDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.34,{"v":3E-32,"d":"3.00E-32"},31.5228787452803,null,0.049,"[NR] unit decrease","NR [NR] (imputed)","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,"NR",{"v":4e-32,"d":"4.00E-32"},31.397940008672,null,0.133,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[59,"rs372038686",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,"NR",{"v":6e-32,"d":"6.00E-32"},31.2218487496163,null,0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.074,{"v":7e-32,"d":"7.00E-32"},31.1549019599857,"(EA)",0.103,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs77188937",16,56846804,"rs16962399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","NUP93",null,null,"ENSG00000102900",null,null,"rs16962399-C","rs16962399",0,16962399,"intron_variant",0,"NR",{"v":7e-32,"d":"7.00E-32"},31.1549019599857,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63094207,"rs11485618","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11485618-A","rs11485618",0,11485618,"3_prime_UTR_variant",0,0.691,{"v":1e-31,"d":"1.00E-31"},31,"(Trans-ethnic initial)",0.05,"[0.042-0.058] unit increase (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[26,"rs112875651",8,126500031,"rs28601761","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-?","rs28601761",0,28601761,"intron_variant",0,"NR",{"v":1e-31,"d":"1.00E-31"},31,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.45,{"v":2e-31,"d":"2.00E-31"},30.698970004336,null,0.12,"[0.08-0.16] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[8,"rs668948",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(APOB.assay, whole)",4.093,"[NR] unit decrease","Illumina [335603]","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","9q34.2",null,"ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":3e-31,"d":"3.00E-31"},30.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.952,{"v":3e-31,"d":"3.00E-31"},30.5228787452803,"(Hispanic)",0.411,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-31,"d":"4.00E-31"},30.397940008672,"(Carboxypeptidase A2, CPA2.9276.7.3)",0.3,"[0.24-0.36] unit increase","Affymetrix [10572788] (imputed)","N"]
[10,"rs4299376",2,44074431,"rs4245791","2017-03-10",27094239,"Joshi AD","2016-04-16","Gastroenterology","www.ncbi.nlm.nih.gov/pubmed/27094239","Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.","Gallstone disease","8,720 European ancestry cases,  55,152 European ancestry controls","6,489 European ancestry cases, 62,797 European ancestry controls, 1,499 African American cases, 9,145 African American controls, 1,056 Hispanic cases, 2,403 Hispanic controls","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4245791-T","rs4245791",0,4245791,"non_coding_transcript_exon_variant",0,0.69,{"v":5e-31,"d":"5.00E-31"},30.3010299956639,"(EA)",1.28,"[1.25-1.32]","Affymetrix, Illumina [at least 2305318] (imputed)","N"]
[19,"rs3777411",6,160506462,"rs2297363","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","6q25.3","IGF2R, RP11-288H12.3","IGF2R",null,null,"ENSG00000197081",null,null,"rs2297363-A","rs2297363",0,2297363,"intron_variant",0,0.1182093,{"v":8e-31,"d":"8.00E-31"},30.096910013008,"(Cation-independent mannose-6-phosphate receptor)",0.7573,"[0.63-0.88] unit increase","Affymetrix [509946]","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":1e-30,"d":"1.00E-30"},30,"(ENG)",0.394,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2011-01-14",21087763,"Carrasquillo MM","2010-12-10","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/21087763","Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.","Progranulin levels","518 European ancestry controls","459 European ancestry controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.21,{"v":2e-30,"d":"2.00E-30"},29.698970004336,null,0.18,"[0.16-0.20] ng/ml decrease","Illumina [313504]","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":2e-30,"d":"2.00E-30"},29.698970004336,"(EA)",0.133,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid AB1-42 levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":2e-30,"d":"2.00E-30"},29.698970004336,{"$nulls":3},"Illumina [563980]","N"]
[29,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":3e-30,"d":"3.00E-30"},29.5228787452803,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206462,"rs681343","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Childhood ear infection","46,936 European ancestry cases, 74,874 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs681343-C","rs681343",0,681343,"stop_gained",0,0.52,{"v":4e-30,"d":"4.00E-30"},29.397940008672,null,1.11,"[1.1-1.12]","Illumina [at least 560000] (imputed)","N"]
[22,"rs6601599",8,11433780,"rs2409797","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","intergenic","AC022239.1 - LINC00208","ENSG00000269954","ENSG00000170983",null,11577,42,"rs2409797-T","rs2409797",0,2409797,"intergenic_variant",1,0.46977,{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,11.393,"z score decrease","Illumina [18485882] (imputed)","N"]
[47,"rs12608026",18,47118923,"rs3786247","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs3786247-?","rs3786247",0,3786247,"3_prime_UTR_variant",0,"NR",{"v":5e-30,"d":"5.00E-30"},29.3010299956639,null,0.04427,"[0.037-0.052] unit increase novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.52,{"v":7e-30,"d":"7.00E-30"},29.1549019599857,"(Asian initial, BMI unadjusted)",0.1,"[0.082-0.118] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.21,{"v":8e-30,"d":"8.00E-30"},29.096910013008,"(Indian)",18.69,"[15.46-21.92] unit increase","Illumina [551825]","N"]
[59,"rs372038686",23,109716407,"rs5942937","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,16845,47133,"rs5942937-T","rs5942937",0,5942937,"intergenic_variant",1,"NR",{"v":8e-30,"d":"8.00E-30"},29.096910013008,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1235162",6,29206683,"rs150817755","2019-02-21",30285260,"Ikeda M","2018-10-03","Schizophr Bull","www.ncbi.nlm.nih.gov/pubmed/30285260","Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.","Schizophrenia","14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls","NA","6p22.1","OR2G1P","AL672167.1",null,null,"ENSG00000197171",null,null,"rs150817755-T","rs150817755",1,3130820,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,"(EA)",1.261,"[1.22-1.3]","Illumina [6627481] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":1e-29,"d":"1.00E-29"},29,null,0.089,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs6882345",5,156398169,"rs1501908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,7903,58255,"rs1501908-G","rs1501908",0,1501908,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56994528,"rs17231506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-C","rs17231506",0,17231506,"regulatory_region_variant",1,"NR",{"v":2e-29,"d":"2.00E-29"},28.698970004336,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-29,"d":"3.00E-29"},28.5228787452803,"(TG.by.NMR, fasting)",0.056,"[NR] unit increase","Illumina [335603]","N"]
[26,"rs2954021",8,126490972,"rs2954029","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-T","rs2954029",0,2954029,"intron_variant",0,0.47,{"v":3e-29,"d":"3.00E-29"},28.5228787452803,null,0.04,"[NR] unit increase","NR [NR] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.798,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(Hispanic)",0.21,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.916,{"v":5e-29,"d":"5.00E-29"},28.3010299956639,"(EA)",0.079,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.223,{"v":6e-29,"d":"6.00E-29"},28.2218487496163,"(EA)",0.064,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs289713",16,57006378,"rs11076175","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs11076175-?","rs11076175",0,11076175,"intron_variant",0,"NR",{"v":8e-29,"d":"8.00E-29"},28.096910013008,"(Total cholesterol in HDL, conditioned)",0.1511545,"[0.12-0.18] unit decrease","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[50,"rs1065853",19,45415640,"rs445925","2015-06-08",25350695,"Postmus I","2014-10-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/25350695","Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.","Response to statins (LDL cholesterol change)","18,596 European ancestry individuals","23,279 European ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.157,{"v":9e-29,"d":"9.00E-29"},28.0457574905606,null,0.051,"[0.041-0.061] unit decrease","Affymetrix, Illumina, Perlegen [at least 2500000] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.797,{"v":1e-28,"d":"1.00E-28"},28,"(Hispanic)",0.208,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2014-10-28",24586186,"Rueedi R","2014-02-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/24586186","Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.","Urinary metabolites (H-NMR features)","835 European ancestry individuals","601 Brazilian individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.27,{"v":1e-28,"d":"1.00E-28"},28,"(2.0525, Unknown)",0.49,"[NR] unit increase","Illumina [713870] (imputed)","N"]
[41,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,"NR",{"v":1e-28,"d":"1.00E-28"},28,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1235162",6,29244219,"rs144447022","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","6p22.1","NR","AL672167.1",null,null,"ENSG00000197171",null,null,"rs144447022-G","rs144447022",0,144447022,"intron_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,1.25,"[NR]","Illumina [7158791] (imputed)","N"]
[29,"rs4149307",9,107589134,"rs4149310","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149310-?","rs4149310",0,4149310,"intron_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,null,0.06261,"[0.051-0.074] unit decrease novel","Illumina [6108953] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (father's attained age)","415,311 British ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,"NR",{"v":2e-28,"d":"2.00E-28"},27.698970004336,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":3E-28,"d":"3.00E-28"},27.5228787452803,null,0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,"NR",{"v":6e-28,"d":"6.00E-28"},27.2218487496163,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs6882345",5,156390297,"rs6882076","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.35,{"v":7e-28,"d":"7.00E-28"},27.1549019599857,null,1.98,"[1.59-2.37] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[23,"rs4921915",8,18272881,"rs1495741","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-A","rs1495741",0,1495741,"regulatory_region_variant",1,0.78,{"v":1E-27,"d":"1.00E-27"},27,"(1-methylurate)",0.057,"[0.047-0.067] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2008-06-22",18454146,"Chambers JC","2008-05-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18454146","Common genetic variation near MC4R is associated with waist circumference and insulin resistance.","Waist circumference and related phenotypes","2,684 Indian Asian ancestry male individuals","7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-?","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":1E-27,"d":"1.00E-27"},27,"(HDL cholesterol)",null,null,"Illumina [308067]","N"]
[8,"rs693",2,21221399,"rs952275","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136866,786,"rs952275-G","rs952275",0,952275,"intergenic_variant",1,0.43,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Free cholesterol in IDL)",0.11,"[0.09-0.13] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[22,"rs1692821",8,11702375,"rs3947","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","8p23.1","FDFT1, CTSB, RP11-589N15.2","CTSB",null,null,"ENSG00000164733",null,null,"rs3947-A","rs3947",0,3947,"3_prime_UTR_variant",0,0.2748245,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(EA, Cathepsin B)",0.5154,"[0.43-0.61] unit increase","Affymetrix [509946]","N"]
[42,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.874,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(Hispanic)",0.201,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-27,"d":"2.00E-27"},26.698970004336,"(FAM159B)",0.5431671,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[29,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,"NR",{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2009-06-01",19430480,"Barrett JC","2009-05-10","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19430480","Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.","Type 1 diabetes","7,514 European ancestry cases, 9,045 European ancestry controls","4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":3e-27,"d":"3.00E-27"},26.5228787452803,{"$nulls":3},"Affymetrix, Illumina [841622] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":3e-27,"d":"3.00E-27"},26.5228787452803,null,0.01336468,"[NR] unit decrease","Illumina [575353]","N"]
[50,"rs75627662",19,45413576,"rs75627662","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-T","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,0.203,{"v":4e-27,"d":"4.00E-27"},26.397940008672,"(Ras-related protein Rab-14, RAB14.14283.12.3)",0.32,"[0.26-0.38] unit decrease","Affymetrix [10572788] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":5e-27,"d":"5.00E-27"},26.3010299956639,null,0.08159,"[0.067-0.096] unit increase novel","Illumina [6108953] (imputed)","N"]
[6,"rs199900492",1,234853406,"rs558971","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1q42.3","IRF2BP2","AL160408.6",null,null,"ENSG00000282097",null,null,"rs558971-A","rs558971",0,558971,"intron_variant",0,0.47,{"v":5e-27,"d":"5.00E-27"},26.3010299956639,"(Trans-ethnic initial)",0.0398,"[0.033-0.047] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":7e-27,"d":"7.00E-27"},26.1549019599857,null,1.91,"[1.54-2.28] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[42,"rs193695",16,56985139,"rs9989419","2010-01-13",20031538,"Heid IM","2008-10-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20031538","Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.","HDL cholesterol","Up to 4,274 European ancestry individuals","Up to 15,873 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.38,{"v":9e-27,"d":"9.00E-27"},26.0457574905606,null,2.66,"[NR] mg/dl decrease","Affymetrix [up to 2557253] (imputed)","N"]
[14,"rs253412",5,74971846,"rs34361","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","POC5",null,null,"ENSG00000152359",null,null,"rs34361-A","rs34361",0,34361,"intron_variant",0,0.358,{"v":1E-26,"d":"1.00E-26"},26,"(EA)",0.051,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.13,{"v":1E-26,"d":"1.00E-26"},26,null,2.85,"[2.32-3.38] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Myeloid white cell count","169,219 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5177,{"v":1E-26,"d":"1.00E-26"},26,null,0.03834367,"[0.031-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.03923603,"[0.032-0.046] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[41,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,"NR",{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2009-01-14",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","LDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-T","rs6511720",0,6511720,"intron_variant",0,0.1,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,0.26,"[0.18-0.34] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Total cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-T","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.063,{"v":2e-26,"d":"2.00E-26"},25.698970004336,null,13.1251,"[10.72-15.53] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[16,"rs1235162",6,28667669,"rs116137698","2017-08-16",28540026,"Anney RJL","2017-05-22","Mol Autism","www.ncbi.nlm.nih.gov/pubmed/28540026","Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.","Autism spectrum disorder or schizophrenia","schizophrenia cases and controls (see Ripke, 2014), up to 6,197 European ancestry ASD cases, up to 7,377 European ancestry controls, up to 1,190 ASD cases, up to 1,190 controls","NA","6p22.1","GABBR1, GPX5, GPX6, HCG14, HIST1H1B, HIST1H2AI, HIST1H2AJ, HIST1H2AK, HIST1H2AL, HIST1H2AM, HIST1H2BL, HIST1H2BM, HIST1H2BN, HIST1H2BO, HIST1H3H, HIST1H3I, HIST1H3J, HIST1H4J, HIST1H4K, HIST1H4L, LINC01012, LINC01015, LINC01556, LINC01623, LOC100129636, LOC100131289, MAS1L, MOG, NKAPL, OR10C1, OR11A1, OR12D2, OR12D3, OR14J1, OR2B2, OR2B3, OR2B6, OR2H1, OR2H2, OR2J2, OR2J3, OR2W1, OR5V1, PGBD1, SNORD32B, TOB2P1, TRIM27, UBD, ZBED9, ZFP57, ZKSCAN3, ZKSCAN4, ZKSCAN8, ZNF165, ZNF192P1, ZNF311, ZSCAN12, ZSCAN12P1, ZSCAN16, ZSCAN16-AS1, ZSCAN23, ZSCAN26, ZSCAN31, ZSCAN9","LINC00533 - RPSAP2","ENSG00000249032","ENSG00000249814",null,50826,32125,"rs116137698-A","rs116137698",1,35044849,"intergenic_variant",1,null,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,1.22,"[1.17-1.26]","Affymetrix, Illumina [NR]","N"]
[41,"rs261290",15,58680178,"rs261291","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-?","rs261291",0,261291,"intron_variant",0,"NR",{"v":3e-26,"d":"3.00E-26"},25.5228787452803,null,0.04531,"[0.037-0.054] unit increase novel","Illumina [6108953] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":3e-26,"d":"3.00E-26"},25.5228787452803,"(PDZK1-interacting protein 1, PDZK1IP1.8260.13.3)",0.35,"[0.29-0.41] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs140824606",19,45311084,"rs140824606","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","AC092306.1 - BCAM","ENSG00000285128","ENSG00000187244",null,3817,1232,"rs140824606-?","rs140824606",0,140824606,"regulatory_region_variant",1,"NR",{"v":4e-26,"d":"4.00E-26"},25.397940008672,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-?","rs1800961",0,1800961,"missense_variant",0,null,{"v":6e-26,"d":"6.00E-26"},25.2218487496163,null,1.29,"[1.23-1.35]","Affymetrix, Illumina [43000000] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.246,{"v":7e-26,"d":"7.00E-26"},25.1549019599857,"(Asian initial, BMI unadjusted)",0.0963,"[0.078-0.114] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[59,"rs372038686",23,109703961,"rs5985471","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","Xq23","NR","RTL9 - TDGF1P3","ENSG00000243978","ENSG00000225366",null,4399,59579,"rs5985471-C","rs5985471",0,5985471,"intergenic_variant",1,0.592,{"v":7e-26,"d":"7.00E-26"},25.1549019599857,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.209,{"v":9e-26,"d":"9.00E-26"},25.0457574905606,"(Hispanic)",0.194,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":1E-25,"d":"1.00E-25"},25,"(APOB.assay, fasting)",4.355,"[NR] unit decrease","Illumina [335603]","N"]
[35,"rs12721026",11,116791307,"rs78692246","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","11q23.3",null,"SIK3",null,null,"ENSG00000160584",null,null,"rs78692246-?","rs78692246",0,78692246,"intron_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[41,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,"NR",{"v":1E-25,"d":"1.00E-25"},25,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.0163,{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.2821,"[0.23-0.34] unit decrease","NR [8041861] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2013-03-20",23381943,"Williams FM","2013-01-01","Ann Neurol","www.ncbi.nlm.nih.gov/pubmed/23381943","Ischemic stroke is associated with the ABO locus: the EuroCLOT study.","End-stage coagulation","2,100 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,0.81,{"v":2e-25,"d":"2.00E-25"},24.698970004336,"(FVIII)",0.461,"[0.37-0.55] unit decrease","Illumina [NR] (imputed)","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[44,"rs4561509",17,45735706,"rs8078686","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.32","NR","KPNB1",null,null,"ENSG00000108424",null,null,"rs8078686-T","rs8078686",0,8078686,"intron_variant",0,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,null,0.045,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-25,"d":"2.00E-25"},24.698970004336,{"$nulls":3},"Affymetrix [NR]","N"]
[10,"rs11887534",2,44079310,"rs72875462","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p21","NR","ABCG8",null,null,"ENSG00000143921",null,null,"rs72875462-C","rs72875462",0,72875462,"intron_variant",0,0.933,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,"(EA)",0.096,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","intergenic","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.1311,{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.0422,"[0.034-0.05] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,"NR",{"v":3e-25,"d":"3.00E-25"},24.5228787452803,null,0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2018-04-10",29084231,"Davis JP","2017-10-30","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29084231","Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.","Serum total cholesterol levels","8,372 Finnish ancestry males","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-?","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-25,"d":"4.00E-25"},24.397940008672,null,0.399,"unit decrease","Illumina [15144991] (imputed)","N"]
[50,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":5e-25,"d":"5.00E-25"},24.3010299956639,"(Ubiquitin carboxyl-terminal hydrolase 21, USP21.12681.63.3)",1.12,"[0.9-1.34] unit increase","Affymetrix [10572788] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-?","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":6e-25,"d":"6.00E-25"},24.2218487496163,"(LDL-C.assay, whole)",4.027,"[NR] unit increase","Illumina [335603]","N"]
[19,"6:160560880_CATG_C",6,160564476,"rs662138","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-G","rs662138",0,662138,"intron_variant",0,0.163,{"v":7e-25,"d":"7.00E-25"},24.1549019599857,"(isobutyrylcarnitine + 3 other traits)",0.155,"[NR] unit decrease","Affymetrix, Illumina [534665]","N"]
[19,"6:160560880_CATG_C",6,160564476,"rs662138","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-C","rs662138",0,662138,"intron_variant",0,0.83,{"v":9e-25,"d":"9.00E-25"},24.0457574905606,"(X-11261)",0.063,"[0.051-0.075] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[41,"rs17240832",15,58694020,"rs16940212","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","15q21.3","intergenic","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs16940212-T","rs16940212",0,16940212,"intron_variant",0,0.34,{"v":1e-24,"d":"1.00E-24"},24,null,0.0222,"[0.018-0.027] mg/dL increase","Affymetrix [~ 2200000] (imputed)","N"]
[42,"rs3816117",16,57005479,"rs1532624","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","16q13","NLRC5, SLC12A3, HERPUD1, CETP","CETP",null,null,"ENSG00000087237",null,null,"rs1532624-A","rs1532624",0,1532624,"intron_variant",0,0.43,{"v":1e-24,"d":"1.00E-24"},24,null,0.23,"[0.19-0.27] unit increase","Illumina [1361436] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-?","rs780094",0,780094,"intron_variant",0,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,"(mannose)",0.04725,"[NR] unit decrease","Affymetrix [655658]","N"]
[26,"rs112875651",8,126506694,"rs112875651","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte fraction of red cells","170,690 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-A","rs112875651",0,112875651,"intron_variant",0,0.3925,{"v":2e-24,"d":"2.00E-24"},23.698970004336,null,0.03782324,"[0.031-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,"NR",{"v":2e-24,"d":"2.00E-24"},23.698970004336,"(males)",3.3425252,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[2,"rs2986164",1,25732087,"rs61777615","2018-12-17",28957414,"Pilling LC","2017-09-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28957414","Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.","Red cell distribution width","116,666 British ancestry individuals","NA","1p36.11","RHCE","RHCE",null,null,"ENSG00000188672",null,null,"rs61777615-A","rs61777615",0,61777615,"intron_variant",0,"NR",{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.0399529,"[0.032-0.048] unit decrease","Affymetrix [16832071] (imputed)","N"]
[25,"rs4876611",8,116667634,"rs2737265","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","8q23.3","TRPS1","TRPS1",null,null,"ENSG00000104447",null,null,"rs2737265-G","rs2737265",0,2737265,"intron_variant",0,0.2824,{"v":3E-24,"d":"3.00E-24"},23.5228787452803,null,0.04060887,"[0.033-0.048] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-?","rs56131196",0,56131196,"intergenic_variant",1,"NR",{"v":3E-24,"d":"3.00E-24"},23.5228787452803,"(males)",3.3117516,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[35,"rs2072560",11,116607437,"rs1558861","2017-03-14",27599772,"Ram R","2016-09-07","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/27599772","A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.","Hypertriglyceridemia","927 Saudi Arabian ancestry cases, 3,159 Saudi Arabian ancestry controls","317 Saudi Arabian ancestry cases, 1,098 Saudi Arabian ancestry controls","11q23.3","APOA1, APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,78469,11449,"rs1558861-C","rs1558861",0,1558861,"regulatory_region_variant",1,"NR",{"v":4e-24,"d":"4.00E-24"},23.397940008672,null,1.74,"[1.30-2.23]","Affymetrix [~ 8000000] (imputed)","N"]
[37,"rs4766578",12,111932800,"rs7137828","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)","12,758 European ancestry heavy drinkers, 1,326 African American or Afro-Caribbean heavy drinkers, 648 Asian ancestry heavy drinkers, 364 Hispanic or Latin American heavy drinkers, 43,947 European ancestry light drinkers, 8,239 African American or Afro-Caribbean light drinkers, 1,141 Asian ancestry light drinkers, 4,448 Hispanic or Latin American light drinkers","42,079 European ancestry heavy drinkers, 217 African American or Afro-Caribbean heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic ancestry heavy drinkers, 74,757 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-T","rs7137828",0,7137828,"intron_variant",0,0.51,{"v":4e-24,"d":"4.00E-24"},23.397940008672,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p13.3",null,"CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-?","rs12740374",0,12740374,"3_prime_UTR_variant",0,"NR",{"v":5e-24,"d":"5.00E-24"},23.3010299956639,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.57,{"v":5e-24,"d":"5.00E-24"},23.3010299956639,"(HDL)",0.13,"[NR] mmol/l decrease","Illumina [1257079] (imputed)","N"]
[50,"rs4803748",19,45251156,"rs2965169","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","BCL3",null,null,"ENSG00000069399",null,null,"rs2965169-?","rs2965169",0,2965169,"non_coding_transcript_exon_variant",0,"NR",{"v":6e-24,"d":"6.00E-24"},23.2218487496163,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":6e-24,"d":"6.00E-24"},23.2218487496163,null,0.01467512,"[NR] unit decrease","Illumina [575353]","N"]
[35,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.878,{"v":8e-24,"d":"8.00E-24"},23.096910013008,"(APOA5)",0.371,"[0.3-0.44] unit increase","Illumina [> 1000000] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-T","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.1,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,3.14,"[2.51-3.77] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[48,"rs142158911",19,11210912,"rs2228671","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","19p13.2","LDLR","LDLR",null,null,"ENSG00000130164",null,null,"rs2228671-G","rs2228671",0,2228671,"stop_gained",0,0.88,{"v":9e-24,"d":"9.00E-24"},23.0457574905606,null,0.16,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.199,{"v":1e-23,"d":"1.00E-23"},23,"(Hispanic)",0.19,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","12q24.12","ATXN2, SH2B3","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-G","rs653178",0,653178,"intron_variant",0,0.425604052030736,{"v":1e-23,"d":"1.00E-23"},23,null,0.47911206,"[0.39-0.57] unit increase","Illumina [247039]","N"]
[50,"rs111606839",19,45490192,"rs11672748","2019-03-18",30617256,"Jansen IE","2019-01-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30617256","Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.","Alzheimer's disease or family history of Alzheimer's disease","24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls","NA","19q13.32","CLPTM1","CLPTM1",null,null,"ENSG00000104853",null,null,"rs11672748-G","rs11672748",0,11672748,"non_coding_transcript_exon_variant",0,0.3171,{"v":1e-23,"d":"1.00E-23"},23,null,10.028075,"NR z-unit increase","Affymetrix, Illumina [up to 10847151] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-04-26",26974007,"Ellinghaus D","2016-03-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26974007","Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.","Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)","8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(subset analysis)",null,null,"Illumina [130052]","N"]
[15,"rs6882345",5,156390297,"rs6882076","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q33.3","NR","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2326077",8,59393273,"rs4738684","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,29213,9464,"rs4738684-A","rs4738684",0,4738684,"regulatory_region_variant",1,"NR",{"v":2e-23,"d":"2.00E-23"},22.698970004336,null,0.045,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":2e-23,"d":"2.00E-23"},22.698970004336,"(KIN)",0.4950121,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,null,0.386,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[49,"rs58542926",19,19460541,"rs73001065","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19p13.11","CILP2","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.93,{"v":3E-23,"d":"3.00E-23"},22.5228787452803,null,0.114,"[0.09-0.138] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[44,"rs4561509",17,45425115,"rs7206971","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.32","NR","EFCAB13",null,null,"ENSG00000178852",null,null,"rs7206971-G","rs7206971",0,7206971,"intron_variant",0,0.515,{"v":4e-23,"d":"4.00E-23"},22.397940008672,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-G","rs769449",0,769449,"non_coding_transcript_exon_variant",0,0.892,{"v":5e-23,"d":"5.00E-23"},22.3010299956639,"(EA)",0.069,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","8q24.13","intergenic","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.5398,{"v":6e-23,"d":"6.00E-23"},22.2218487496163,null,0.0546,"[0.044-0.065] unit increase","NR [8041861] (imputed)","N"]
[37,"rs4766578",12,111833788,"rs10774624","2017-09-26",27723757,"Jin Y","2016-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27723757","Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.","Vitiligo","2,853 European ancestry cases and 37,405 European ancestry controls","1,827 European ancestry cases and 2,181 European ancestry controls","12q24.12","SH2B3, ATXN2","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-G","rs10774624",0,10774624,"intron_variant",0,0.5048,{"v":6e-23,"d":"6.00E-23"},22.2218487496163,null,1.2693577,"[1.2-1.33]","Illumina [8966411] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","up to 92,771 European ancestry males, up to 113,387 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":8e-23,"d":"8.00E-23"},22.096910013008,"(men)",0.052,"[NR] unit increase","Affymetrix, Illumina, Perlegen [2437193] (imputed)","N"]
[41,"rs261290",15,58678512,"rs10468017","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.3,{"v":8e-23,"d":"8.00E-23"},22.096910013008,null,0.1,"[0.06-0.14] s.d. increase","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160564476,"rs662138","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-C","rs662138",0,662138,"intron_variant",0,0.83,{"v":1E-22,"d":"1.00E-22"},22,"(X-03056--N-[3-(2-oxopyrrolidin-1-yl)propyl]acetamide)",0.034,"[0.026-0.042] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.0752,{"v":1E-22,"d":"1.00E-22"},22,"(Trans-ethnic initial)",0.0714,"[0.058-0.084] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[33,"rs6485802",11,48018355,"rs4752805","2018-05-11",29617998,"Gao XR","2018-03-28","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/29617998","Genome-Wide Association Analyses Identify New Loci Influencing Intraocular Pressure.","Intraocular pressure","115,486 European ancestry individuals","NA","11p11.2","PTPRJ","PTPRJ",null,null,"ENSG00000149177",null,null,"rs4752805-A","rs4752805",0,4752805,"intron_variant",0,0.7464,{"v":1E-22,"d":"1.00E-22"},22,null,0.152,"[0.12-0.18] unit decrease","Affymetrix [~ 11900000] (imputed)","N"]
[57,"rs5754102",22,21928916,"rs181360","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs181360-T","rs181360",0,181360,"intron_variant",0,0.801,{"v":1E-22,"d":"1.00E-22"},22,"(Trans-ethnic initial)",0.0376,"[0.029-0.046] unit increase (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[8,"rs668948",2,21397182,"rs506585","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,31038,24208,"rs506585-?","rs506585",0,506585,"intergenic_variant",1,"NR",{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(LDL.total, whole)",0.04,"[NR] unit decrease","Illumina [335603]","N"]
[15,"rs6882345",5,156390297,"rs6882076","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-T","rs6882076",0,6882076,"regulatory_region_variant",1,0.35,{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,1.67,"[1.3-2.04] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[38,"rs2244608",12,121416650,"rs1169288","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","12q24.31","HNF1A","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.666,{"v":2e-22,"d":"2.00E-22"},21.698970004336,"(Trans-ethnic initial)",0.0375,"[0.03-0.045] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[57,"rs5754102",22,21976934,"rs7444","2016-09-23",26502338,"Bentham J","2015-10-26","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26502338","Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.","Systemic lupus erythematosus","5,201 European ancestry cases, 9,066 European ancestry controls","2,018 European ancestry cases, 6,925 European ancestry controls","22q11.21","UBE2L3, YDJC","UBE2L3",null,null,"ENSG00000185651",null,null,"rs7444-C","rs7444",0,7444,"3_prime_UTR_variant",0,null,{"v":2e-22,"d":"2.00E-22"},21.698970004336,null,1.27,"[1.21–1.33]","Illumina [644674]","N"]
[24,"rs2326077",8,59370320,"rs4738679","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,6260,32417,"rs4738679-G","rs4738679",0,4738679,"intergenic_variant",1,"NR",{"v":3e-22,"d":"3.00E-22"},21.5228787452803,null,0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2326077",8,59370320,"rs4738679","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,6260,32417,"rs4738679-G","rs4738679",0,4738679,"intergenic_variant",1,0.337,{"v":3e-22,"d":"3.00E-22"},21.5228787452803,"(EA)",0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":4e-22,"d":"4.00E-22"},21.397940008672,null,0.047,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111784051",19,45389596,"rs7254892","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","19q13.32","APOE, APOC1, APOC2","NECTIN2, AC011481.2",null,null,"ENSG00000130202, ENSG00000267114",null,null,"rs7254892-A","rs7254892",0,7254892,"intron_variant",0,0.07,{"v":4e-22,"d":"4.00E-22"},21.397940008672,"(BMI unadjusted)",0.408,"[0.33-0.49] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[22,"rs11250098",8,11061792,"rs6981523","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","8p23.1","NR","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,612,43343,"rs6981523-T","rs6981523",0,6981523,"intergenic_variant",1,0.50684,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,null,0.054139,"[0.043-0.065] unit increase","Illumina [18485882] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.234,{"v":5e-22,"d":"5.00E-22"},21.3010299956639,"(East Asian)",0.15,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","LDL cholesterol","8,589 European ancestry individuals","12,981 European ancestry individuals","2p24.1","APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-G","rs562338",0,562338,"intergenic_variant",1,0.82,{"v":6e-22,"d":"6.00E-22"},21.2218487496163,null,4.89,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","20q13.12",null,"HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-?","rs1800961",0,1800961,"missense_variant",0,"NR",{"v":6e-22,"d":"6.00E-22"},21.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","19p13.11","CSPG3, CILP2, PBX4","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.07,{"v":7e-22,"d":"7.00E-22"},21.1549019599857,null,3.11,"[2.37-3.85] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.2288,{"v":8e-22,"d":"8.00E-22"},21.096910013008,null,0.12353132,"[0.098-0.149] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.22,{"v":9e-22,"d":"9.00E-22"},21.0457574905606,null,0.13,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[6,"rs199900492",1,234853059,"rs556107","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","1q42.3","NR","AL160408.6",null,null,"ENSG00000282097",null,null,"rs556107-T","rs556107",0,556107,"intron_variant",0,0.601,{"v":1e-21,"d":"1.00E-21"},21,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","5q13.3","HMGCR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.475,{"v":1e-21,"d":"1.00E-21"},21,"(Asian initial, BMI unadjusted)",0.0773,"[0.061-0.093] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[20,"rs35348663",7,73042614,"rs7786376","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Gamma glutamyl transferase levels","118,309 Japanese ancestry individuals","NA","7q11.23","MLXIPL, VPS37D","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3741,39541,"rs7786376-?","rs7786376",0,7786376,"intergenic_variant",1,"NR",{"v":1e-21,"d":"1.00E-21"},21,null,0.06432,"[0.051-0.078] unit decrease novel","Illumina [6108953] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-09-14",27618452,"Ehret GB","2016-09-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618452","The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.","Diastolic blood pressure","up to 201,529 European ancestry individuals","up to 140,886 European ancestry individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.475,{"v":1e-21,"d":"1.00E-21"},21,null,0.362,"[0.29-0.44] mm Hg increase","Affymetrix, Illumina, Perlegen [128272]","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.209,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(Hispanic)",0.175,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2326077",8,59353534,"rs13277801","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B",null,null,"ENSG00000215114",null,null,"rs13277801-C","rs13277801",0,13277801,"intron_variant",0,0.34,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(EA)",0.046,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(EA)",0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.19,{"v":2e-21,"d":"2.00E-21"},20.698970004336,null,0.067,"[NR] unit decrease","NR [NR] (imputed)","N"]
[51,"rs35106244",19,49206462,"rs681343","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs681343-T","rs681343",0,681343,"stop_gained",0,0.507,{"v":2e-21,"d":"2.00E-21"},20.698970004336,"(Transcobalamin-1, TCN1.11232.46.3)",0.23,"[0.19-0.27] unit increase","Affymetrix [10572788] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte count","169,822 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5177,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.03386557,"[0.027-0.041] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[41,"rs55966152",15,58552606,"rs7165301","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7165301-?","rs7165301",0,7165301,"intron_variant",0,"NR",{"v":3e-21,"d":"3.00E-21"},20.5228787452803,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs157592",19,45422160,"rs12721051","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs12721051-G","rs12721051",0,12721051,"3_prime_UTR_variant",0,0.24,{"v":3e-21,"d":"3.00E-21"},20.5228787452803,null,0.14,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[24,"rs2326077",8,59311697,"rs1030431","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","AC092819.1 - UBXN2B","ENSG00000253281","ENSG00000215114",null,127019,12126,"rs1030431-A","rs1030431",0,1030431,"intergenic_variant",1,"NR",{"v":4e-21,"d":"4.00E-21"},20.397940008672,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Systolic blood pressure","approximately 422,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs7412-?","rs7412",0,7412,"missense_variant",0,"NR",{"v":4e-21,"d":"4.00E-21"},20.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs75627662",19,45416178,"rs483082","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs483082-T","rs483082",0,483082,"non_coding_transcript_exon_variant",0,0.231,{"v":4e-21,"d":"4.00E-21"},20.397940008672,"(Glutathione S-transferase Mu 1, GSTM1.7239.9.3)",0.27,"[0.21-0.33] unit increase","Affymetrix [10572788] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2019-01-11",30054458,"Xue A","2018-07-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30054458","Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.","Type 2 diabetes","61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.387154700626533,{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,0.0692,"[0.055-0.084] unit decrease","NR [5035015] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":5e-21,"d":"5.00E-21"},20.3010299956639,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs4665978",2,27716004,"rs780088","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Age at menopause","approximately 143,000 European ancestry individuals","NA","2p23.3",null,"FNDC4",null,null,"ENSG00000115226",null,null,"rs780088-?","rs780088",0,780088,"intron_variant",0,"NR",{"v":6e-21,"d":"6.00E-21"},20.2218487496163,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[21,"rs615632",8,9796321,"rs615632","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Neuroticism","523,783 European ancestry individuals","59,206 European ancestry individuals","8p23.1","NR","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,33445,111674,"rs615632-T","rs615632",0,615632,"intergenic_variant",1,0.542305889708364,{"v":6e-21,"d":"6.00E-21"},20.2218487496163,null,0.017517187,"[0.014-0.021] unit increase","NR [NR]","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,0.215,{"v":7e-21,"d":"7.00E-21"},20.1549019599857,"(EA)",0.054,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19329924,"rs2228603","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or LDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol)","NA","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2228603-T","rs2228603",0,2228603,"missense_variant",0,"NR",{"v":7e-21,"d":"7.00E-21"},20.1549019599857,{"$nulls":3},"NR [2501749] (imputed)","N"]
[8,"rs668948",2,21399216,"rs478442","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,33072,22174,"rs478442-?","rs478442",0,478442,"regulatory_region_variant",1,"NR",{"v":8e-21,"d":"8.00E-21"},20.096910013008,{"$nulls":3},"Affymetrix [NR]","N"]
[24,"rs2326077",8,59392324,"rs9297994","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8q12.1","intergenic","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,28264,10413,"rs9297994-A","rs9297994",0,9297994,"intergenic_variant",1,0.6903,{"v":8e-21,"d":"8.00E-21"},20.096910013008,null,0.0282,"[0.022-0.034] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.233,{"v":9e-21,"d":"9.00E-21"},20.0457574905606,"(Hispanic)",0.166,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2008-06-22",18439548,"Ridker PM","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439548","Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.","C-reactive protein","6,345 European ancestry female individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":9e-21,"d":"9.00E-21"},20.0457574905606,null,0.26,"[NR] mg/dl decrease","Illumina [336108]","N"]
[16,"rs1235162",6,29356331,"rs9257809","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","OR12D3, OR12D2","OR5V1, OR5V1, OR5V1, OR5V1, OR5V1",null,null,"ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000112461, ENSG00000243441",null,null,"rs9257809-G","rs9257809",0,9257809,"intron_variant",0,0.233,{"v":1e-20,"d":"1.00E-20"},20,{"$nulls":3},"Illumina [118177]","N"]
[16,"rs1235162",6,29461730,"rs1233491","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","MAS1L, LOC729653","RPS17P1 - AL662860.1","ENSG00000213900","ENSG00000229274",null,4277,3556,"rs1233491-C","rs1233491",0,1233491,"intergenic_variant",1,0.23,{"v":1e-20,"d":"1.00E-20"},20,{"$nulls":3},"Illumina [118177]","N"]
[35,"rs2072560",11,116586283,"rs7350481","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","BUD13","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,57315,32603,"rs7350481-A","rs7350481",0,7350481,"regulatory_region_variant",1,0.19,{"v":1e-20,"d":"1.00E-20"},20,"(Indian)",16.32,"[12.89-19.75] unit increase","Illumina [551825]","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":1e-20,"d":"1.00E-20"},20,"(Epididymal-specific lipocalin-10, LCN10.13007.66.3)",0.31,"[0.25-0.37] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid AB1-42 levels","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-?","rs4420638",0,4420638,"intergenic_variant",1,null,{"v":1e-20,"d":"1.00E-20"},20,null,274.6386,"[NR] unit increase","Illumina [575353]","N"]
[56,"rs1800961",20,43042364,"rs1800961","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,"NR",{"v":1e-20,"d":"1.00E-20"},20,{"$nulls":3},"NR [2501549] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p13.3","CELSR2, PSRC1, SPRT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-?","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(LDL.total, fasting)",0.043,"[NR] unit decrease","Illumina [335603]","N"]
[24,"rs2326077",8,59392324,"rs9297994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,28264,10413,"rs9297994-G","rs9297994",0,9297994,"intergenic_variant",1,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count","172,435 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.1824,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.0430554,"[0.034-0.052] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.226,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(East Asian)",0.146,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,"NR",{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs2238681",19,45401666,"rs8106922","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs8106922-A","rs8106922",0,8106922,"intron_variant",0,0.615581,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,1.624312,"[1.47-1.78]","Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2013-07-31",23455636,"Fritsche LG","2013-03-03","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23455636","Seven new loci associated with age-related macular degeneration.","Age-related macular degeneration","6,713 European ancestry cases, 48,402 European ancestry contols, 110 Southern Indian ancestry cases, 119 Southern Indian ancestry controls, 827 Japanese ancestry cases, 3,323 Japanese ancestry controls","9,070 European ancestry cases, 7,683 European ancestry contols, 461 East Asian ancestry cases, 547 East Asian ancestry controls","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.83,{"v":2e-20,"d":"2.00E-20"},19.698970004336,null,1.3,"[1.24-1.36]","Affymetrix, Illumina [2442884] (imputed)","N"]
[50,"rs79429216",19,45445517,"rs79429216","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs79429216-A","rs79429216",0,79429216,"5_prime_UTR_variant",0,0.013,{"v":2e-20,"d":"2.00E-20"},19.698970004336,"(Cofilin-1, CFL1.4203.50.2)",1,"[0.78-1.22] unit increase","Affymetrix [10572788] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-07-30",27618447,"Surendran P","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618447","Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.","Diastolic blood pressure","up to 165,276 European ancestry individuals, up to 27,487 South Asian ancestry individuals","up to 125,713 European ancestry individuals, up to 2,641 South Asian ancestry individuals, 4,632 Hispanic individuals, 22,077 African American individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.4594,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,null,0.032,"unit increase","Illumina [242296]","N"]
[51,"rs35106244",19,49206985,"rs602662","2009-04-01",19303062,"Tanaka T","2009-03-18","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/19303062","Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.","Folate pathway vitamin levels","2,934 European ancestry individuals","686 European ancestry individuals","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs602662-A","rs602662",0,602662,"missense_variant",0,0.53,{"v":3e-20,"d":"3.00E-20"},19.5228787452803,"(vitamin B12)",49.77,"[37.09-62.45] pg/ml increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.03395389,"[0.027-0.041] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2010-02-28",20081858,"Dupuis J","2010-01-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20081858","New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.","Fasting blood insulin","38,238 European ancestry individuals","62,264 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.62,{"v":4e-20,"d":"4.00E-20"},19.397940008672,null,0.032,"[0.024-0.04] pmol/L increase (replication)","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[24,"rs2326077",8,59393273,"rs4738684","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,29213,9464,"rs4738684-A","rs4738684",0,4738684,"regulatory_region_variant",1,0.341,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(EA)",0.045,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(EA)",0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49209010,"rs503279","2012-02-24",21886157,"Suhre K","2011-08-31","Nature","www.ncbi.nlm.nih.gov/pubmed/21886157","Human metabolic individuality in biomedical and pharmaceutical research.","Metabolic traits","2,820 European ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs503279-C","rs503279",0,503279,"3_prime_UTR_variant",0,0.464,{"v":4e-20,"d":"4.00E-20"},19.397940008672,"(SM-11 + 2 other traits)",0.129,"[NR] unit increase","Affymetrix, Illumina [534665]","N"]
[9,"rs3817588",2,27743215,"rs814295","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs814295-A","rs814295",0,814295,"intron_variant",0,0.67,{"v":5e-20,"d":"5.00E-20"},19.3010299956639,"(BMI unadjusted)",0.102,"[0.08-0.124] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":5e-20,"d":"5.00E-20"},19.3010299956639,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2326077",8,59392324,"rs9297994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,28264,10413,"rs9297994-G","rs9297994",0,9297994,"intergenic_variant",1,0.339,{"v":6e-20,"d":"6.00E-20"},19.2218487496163,"(EA)",0.044,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","11p11.2","NR","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-C","rs3817334",0,3817334,"intron_variant",0,"NR",{"v":6e-20,"d":"6.00E-20"},19.2218487496163,null,0.023,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[37,"rs11066320",12,112273499,"rs11513729","2018-10-18",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption interaction (2df test)","63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers,  2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers","12q24.12","MAPKAPK5-AS1","ALDH2 - MAPKAPK5-AS1","ENSG00000111275","ENSG00000234608",null,18166,4069,"rs11513729-T","rs11513729",0,11513729,"intergenic_variant",1,0.4,{"v":6e-20,"d":"6.00E-20"},19.2218487496163,"(AA, EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[16,"rs1235162",6,28803291,"rs9257248","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","LOC442181, LOC401242","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,51510,2355,"rs9257248-A","rs9257248",0,9257248,"intergenic_variant",1,0.217,{"v":7e-20,"d":"7.00E-20"},19.1549019599857,{"$nulls":3},"Illumina [118177]","N"]
[35,"rs964184",11,116648917,"rs964184","2012-11-21",22916037,"Inouye M","2012-08-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22916037","Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.","Metabolite levels","6,608 European ancestry individuals","NA","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,0.14,{"v":8e-20,"d":"8.00E-20"},19.096910013008,{"$nulls":3},"Illumina [~ 2000000] (imputed)","N"]
[8,"rs533617",2,21233972,"rs533617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs533617-T","rs533617",0,533617,"missense_variant",0,0.96,{"v":9e-20,"d":"9.00E-20"},19.0457574905606,"(EA)",0.087,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62926371,"rs7547965","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs7547965-A","rs7547965",0,7547965,"intron_variant",0,0.658,{"v":1e-19,"d":"1.00E-19"},19,"(ANGPTL3)",0.228,"[0.18-0.28] unit increase","Illumina [> 1000000] (imputed)","N"]
[16,"rs1235162",6,29283672,"rs3129682","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","6p22.1","GABBR1, OR12D3, XXbac-BPG308K3.5, TRIM27, AL662791.1, OR2AD1P, OR2P1P, OR2B3, XXbac-BCX196D17.5, OR2N1P, OR2H4P, OR2B4P, XXbac-BPG308K3.6, RPL13P, ZNF90P2, HCG14, RNU6-930P, LINC01556, KRT18P1, RN7SL471P, HCG15, HCG16, ZNF311, XXbac-BPG258E24.10, OR2W1, SAR1P1, OR2J3, OR2J4P, OR2J2, AL645937.1, XXbac-BPG308J9.3, OR2U2P, OR14J1, OR5V1, OR10C1, OR11A1, XXbac-BPG13B8.11, OR2H1, UBDP1, MAS1LP1, MAS1L, RPS17P1, XXbac-BPG13B8.10, OR2I1P, UBD","OR14J1 - DDX6P1","ENSG00000234100","ENSG00000225927",null,2878,13731,"rs3129682-T","rs3129682",0,3129682,"intergenic_variant",1,0.07742915,{"v":1e-19,"d":"1.00E-19"},19,"(EA, MHC class I polypeptide-related sequence B)",0.7369,"[0.58-0.89] unit decrease","Affymetrix [509946]","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","11p11.2","NR","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-C","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":1e-19,"d":"1.00E-19"},19,null,0.023,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[44,"rs4561509",17,45735706,"rs8078686","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","17q21.32","NR","KPNB1",null,null,"ENSG00000108424",null,null,"rs8078686-T","rs8078686",0,8078686,"intron_variant",0,0.487,{"v":1e-19,"d":"1.00E-19"},19,"(EA)",0.042,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,{"v":1e-19,"d":"1.00E-19"},19,"(ADP-ribosylation factor-like protein 1, ARL1.12392.30.3)",0.3,"[0.24-0.36] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.043,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(ACE)",0.316,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs118146573",16,57000938,"rs118146573","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs118146573-G","rs118146573",0,118146573,"intron_variant",0,0.883,{"v":2E-19,"d":"2.00E-19"},18.698970004336,"(EA)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111606839",19,45440529,"rs73045691","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1P1 - APOC4","ENSG00000214855","ENSG00000267467",null,5886,4966,"rs73045691-?","rs73045691",0,73045691,"intergenic_variant",1,"NR",{"v":2E-19,"d":"2.00E-19"},18.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,0.03525,"[0.028-0.043] unit decrease novel","Illumina [6108953] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(Hepatocyte growth factor receptor)",0.4365,"[0.34-0.53] unit decrease","Affymetrix [509946]","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(Thrombospondin type-1 domain-containing protein 1, THSD1.5621.64.3)",0.29,"[0.23-0.35] unit decrease","Affymetrix [10572788] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.682,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[55,"rs6129762",20,39672618,"rs6029526","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6029526-A","rs6029526",0,6029526,"intron_variant",0,0.47,{"v":3e-19,"d":"3.00E-19"},18.5228787452803,null,1.41,"[1.08-1.74] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.1824,{"v":4e-19,"d":"4.00E-19"},18.397940008672,null,0.04146991,"[0.032-0.051] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2013-03-19",23222517,"van der Harst P","2012-12-05","Nature","www.ncbi.nlm.nih.gov/pubmed/23222517","Seventy-five genetic loci influencing the human red blood cell.","Red blood cell traits","62,553 European ancestry individuals, 9,308 South Asian ancestry individuals","63,506 European ancestry individuals","12q24.12","SH2B3, ATXN2","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.48,{"v":4e-19,"d":"4.00E-19"},18.397940008672,"(EA, Hgb)",0.051,"[0.039-0.063] unit increase","Affymetrix, Illumina, Perlegen [2711806] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.6053,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,null,0.03251663,"[0.025-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-T","rs5167",0,5167,"missense_variant",0,0.643,{"v":5e-19,"d":"5.00E-19"},18.3010299956639,"(EA)",0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[10,"rs4299376",2,44073881,"rs6544713","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","2p21","ABCG5, ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs6544713-T","rs6544713",0,6544713,"non_coding_transcript_exon_variant",0,0.3018,{"v":6e-19,"d":"6.00E-19"},18.2218487496163,null,0.0549,"[0.043-0.067] unit increase","NR [8041861] (imputed)","N"]
[21,"rs2126259",8,9183664,"rs4841133","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841133-A","rs4841133",0,4841133,"non_coding_transcript_exon_variant",0,0.1,{"v":6e-19,"d":"6.00E-19"},18.2218487496163,null,0.064,"[0.05-0.078] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[16,"rs1235162",6,29057639,"rs3129788","2018-04-27",26651848,"Rivera NV","2016-05-01","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/26651848","High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.","Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)","664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases","413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases","6p22.1","OR2B3P, OR2J3","OR2B3 - OR2J1","ENSG00000233687","ENSG00000225441",null,2549,9795,"rs3129788-A","rs3129788",0,3129788,"regulatory_region_variant",1,0.217,{"v":7e-19,"d":"7.00E-19"},18.1549019599857,{"$nulls":3},"Illumina [118177]","N"]
[35,"rs58065809",11,117003749,"rs4938344","2017-05-11",28031287,"Sasayama D","2016-11-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28031287","Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.","Cerebrospinal fluid biomarker levels","133 Japanese ancestry individuals.","NA","11q23.3","NR","AP000936.2 - AP005018.2","ENSG00000225236","ENSG00000254851",null,13852,2495,"rs4938344-?","rs4938344",0,4938344,"intergenic_variant",1,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,"(Proprotein convertase subtilisin/kexin type 7)",null,null,"Illumina [514227]","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":7e-19,"d":"7.00E-19"},18.1549019599857,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs12608026",18,47118923,"rs3786247","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs3786247-T","rs3786247",0,3786247,"3_prime_UTR_variant",0,0.6,{"v":7e-19,"d":"7.00E-19"},18.1549019599857,"(Asian initial, BMI unadjusted)",0.094,"[0.074-0.114] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[37,"rs11066320",12,112684221,"rs7953257","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)","12,758 European ancestry heavy drinkers, 1,326 African American or Afro-Caribbean heavy drinkers, 648 Asian ancestry heavy drinkers, 364 Hispanic or Latin American heavy drinkers, 43,947 European ancestry light drinkers, 8,239 African American or Afro-Caribbean light drinkers, 1,141 Asian ancestry light drinkers, 4,448 Hispanic or Latin American light drinkers","42,079 European ancestry heavy drinkers, 217 African American or Afro-Caribbean heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic ancestry heavy drinkers, 74,757 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers","12q24.13","HECTD4","HECTD4",null,null,"ENSG00000173064",null,null,"rs7953257-A","rs7953257",0,7953257,"intron_variant",0,0.45,{"v":8e-19,"d":"8.00E-19"},18.096910013008,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[9,"rs1260326",2,27598097,"rs4665972","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte count","170,761 European ancestry individuals","NA","2p23.3","SNX17","SNX17",null,null,"ENSG00000115234",null,null,"rs4665972-C","rs4665972",0,4665972,"intron_variant",0,0.6051,{"v":1e-18,"d":"1.00E-18"},18,null,0.03246703,"[0.025-0.04] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[38,"rs2244608",12,121416650,"rs1169288","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","12q24.31","HNF1A, HNF1A-AS1","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.6725,{"v":1e-18,"d":"1.00E-18"},18,null,0.049,"[0.038-0.06] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[41,"rs1077835",15,58723939,"rs2070895","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-A","rs2070895",0,2070895,"intron_variant",0,0.21,{"v":1e-18,"d":"1.00E-18"},18,"(1-palmitoylglycerophosphoethanolamine)",0.03,"[0.024-0.036] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid AB1-42 levels","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":1e-18,"d":"1.00E-18"},18,null,301.1457,"[NR] unit increase","Illumina [575353]","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","2p24.1",null,"APOB",null,null,"ENSG00000084674",null,null,"rs1042034-?","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":2e-18,"d":"2.00E-18"},17.698970004336,"(EA)",0.072,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18272535,"rs35246381","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,13807,112276,"rs35246381-T","rs35246381",0,35246381,"regulatory_region_variant",1,0.732,{"v":2e-18,"d":"2.00E-18"},17.698970004336,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[29,"rs1800978",9,107653426,"rs12686004","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","HDL cholesterol","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-T","rs12686004",0,12686004,"intron_variant",0,0.21,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.0217,"[0.017-0.027] mg/dL decrease","Affymetrix [~ 2200000] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs111371860",19,45345787,"rs111371860","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,21109,3645,"rs111371860-?","rs111371860",0,111371860,"intergenic_variant",1,"NR",{"v":2e-18,"d":"2.00E-18"},17.698970004336,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid t-tau:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,null,{"v":2e-18,"d":"2.00E-18"},17.698970004336,null,0.113894,"[NR] unit decrease","Illumina [575353]","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.32,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,1.59,"[1.22-1.96] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Metabolite levels","8,330 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(Ala, Gln)",0.15,"[0.11-0.19] unit decrease","Illumina [~ 7700000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","11q23.3","APOA4, APOA5, APOA1, APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,"(Trans-ethnic initial)",0.0855,"[0.07-0.101] unit decrease (EA Beta value)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2009-05-19",19430483,"Newton-Cheh C","2009-05-10","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19430483","Genome-wide association study identifies eight loci associated with blood pressure.","Diastolic blood pressure","34,433 European ancestry individuals","Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals","12q24.12","SH2B3, ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.53,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.46,"[0.36-0.56] mm Hg decrease","Affymetrix, Illumina [2497993] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Cerebrospinal fluid p-tau levels","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, OMM40, APOC1, APOC1P1, APOC4, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":3e-18,"d":"3.00E-18"},17.5228787452803,null,0.51,"[0.39-0.63] unit increase","Illumina [8454806] (imputed)","N"]
[37,"rs4766578",12,111904371,"rs4766578","2012-07-11",22561518,"Jin Y","2012-05-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22561518","Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.","Vitiligo","418 European ancestry cases, 2,810 European ancestry controls","1,377 European ancestry cases, 1,284 European ancestry controls","12q24.12","SH2B3","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-T","rs4766578",0,4766578,"intron_variant",0,0.52,{"v":4e-18,"d":"4.00E-18"},17.397940008672,null,1.32,"[NR]","Illumina [495821]","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,"NR",{"v":4e-18,"d":"4.00E-18"},17.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[51,"rs35106244",19,49206108,"rs679574","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs679574-G","rs679574",0,679574,"intron_variant",0,0.507,{"v":4e-18,"d":"4.00E-18"},17.397940008672,"(Protein FAM177A1, FAM177A1.8039.41.3)",0.21,"[0.17-0.25] unit decrease","Affymetrix [10572788] (imputed)","N"]
[35,"rs180327",11,116611827,"rs180349","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82859,7059,"rs180349-A","rs180349",0,180349,"intergenic_variant",1,0.249,{"v":5e-18,"d":"5.00E-18"},17.3010299956639,"(East Asian)",0.133,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":6e-18,"d":"6.00E-18"},17.2218487496163,null,0.316,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":7e-18,"d":"7.00E-18"},17.1549019599857,"(Intercellular adhesion molecule 5, ICAM5.5124.62.3)",0.28,"[0.22-0.34] unit decrease","Affymetrix [10572788] (imputed)","N"]
[36,"rs2241212",12,109986918,"rs888194","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","12q24.11",null,"UBE3B - MMAB","ENSG00000151148","ENSG00000139428",null,12408,4624,"rs888194-?","rs888194",0,888194,"intergenic_variant",1,"NR",{"v":7e-18,"d":"7.00E-18"},17.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2016-12-01",26879886,"Wakil SM","2016-02-16","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/26879886","A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.","Low high density lipoprotein cholesterol levels","1,747 Saudi Arab ancestry cases, 2,335 Saudi Arab ancestry controls","517 Saudi Arab ancestry cases, 896 Saudi Arab ancestry controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,"NR",{"v":8e-18,"d":"8.00E-18"},17.096910013008,null,1.51,"[1.29–1.77]","Affymetrix [~ 8000000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2013-03-19",23222517,"van der Harst P","2012-12-05","Nature","www.ncbi.nlm.nih.gov/pubmed/23222517","Seventy-five genetic loci influencing the human red blood cell.","Red blood cell traits","62,553 European ancestry individuals, 9,308 South Asian ancestry individuals","63,506 European ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.8,{"v":9e-18,"d":"9.00E-18"},17.0457574905606,"(EA, RBCC)",0.021,"[0.015-0.027] unit increase","Affymetrix, Illumina, Perlegen [2711806] (imputed)","N"]
[5,"rs3832016",1,109817192,"rs7528419","2011-11-16",22003152,"Grallert H","2011-10-14","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/22003152","Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.","Lipoprotein-associated phospholipase A2 activity and mass","12,126 European ancestry individuals, 1,538 individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs7528419-A","rs7528419",0,7528419,"3_prime_UTR_variant",0,0.79,{"v":1e-17,"d":"1.00E-17"},17,"(Activity concentrations)",0.035,"[0.027-0.043] unit increase","Affymetrix, Illumina [2661766] (imputed)","N"]
[8,"rs668948",2,21378805,"rs312985","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","2p24.1","APOB","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,12661,42585,"rs312985-?","rs312985",0,312985,"regulatory_region_variant",1,"NR",{"v":1e-17,"d":"1.00E-17"},17,"(LDL.total, fasting)",0.041,"[NR] unit decrease","Illumina [335603]","N"]
[21,"rs2126259",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-17,"d":"1.00E-17"},17,null,0.064,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723426,"rs1077835","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.588,{"v":1e-17,"d":"1.00E-17"},17,"(East Asian)",0.116,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62924448,"rs9988450","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs9988450-C","rs9988450",0,9988450,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-A","rs599839",0,599839,"regulatory_region_variant",1,0.93,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(BMI unadjusted)",0.162,"[0.13-0.2] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[6,"rs199900492",1,234853268,"rs557933","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6",null,null,"ENSG00000282097",null,null,"rs557933-A","rs557933",0,557933,"intron_variant",0,0.477,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(EA)",0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21291529,"rs668948","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","2p24.1","intergenic","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,24584,55260,"rs668948-A","rs668948",0,668948,"intergenic_variant",1,0.815,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.063,"[0.048-0.078] unit increase","NR [8041861] (imputed)","N"]
[24,"rs2326077",8,59392324,"rs9297994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q12.1","NR","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,28264,10413,"rs9297994-G","rs9297994",0,9297994,"intergenic_variant",1,0.339,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(EA)",0.042,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11820589",11,116619073,"rs28927680","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","11q23.3","ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs28927680-G","rs28927680",0,28927680,"3_prime_UTR_variant",0,0.07,{"v":2e-17,"d":"2.00E-17"},16.698970004336,null,0.26,"[0.20-0.32] unit increase","Affymetrix [389878]","N"]
[47,"rs9304381",18,47181668,"rs2156552","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,4138,84525,"rs2156552-A","rs2156552",0,2156552,"intergenic_variant",1,0.164,{"v":2e-17,"d":"2.00E-17"},16.698970004336,"(EA)",0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs59136961",6,34831761,"rs9462031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9462031-T","rs9462031",0,9462031,"intron_variant",0,0.1553,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,0.04316542,"[0.033-0.053] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[47,"rs9304381",18,47172283,"rs2187375","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,46731,4437,"rs2187375-A","rs2187375",0,2187375,"intergenic_variant",1,0.17,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,"(X-03094)",0.022,"[0.016-0.028] unit decrease","Affymetrix, Illumina [2100000] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2013-04-23",21418511,"Deelen J","2011-03-21","Aging Cell","www.ncbi.nlm.nih.gov/pubmed/21418511","Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.","Longevity","403 European ancestry cases, 1,670 European ancestry controls","1,578 European ancestry cases, 1,997 European ancestry controls, 2,168 cases, 3,915 controls","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,0.855,{"v":3e-17,"d":"3.00E-17"},16.5228787452803,null,1.41,"[1.30-1.54]","Illumina [516721]","N"]
[9,"rs1260326",2,27742603,"rs780093","2010-10-15",20884846,"Yang Q","2010-09-30","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/20884846","Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.","Urate levels","28,283 European ancestry individuals","22,054 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":4e-17,"d":"4.00E-17"},16.397940008672,"(Urate)",5.15,"[3.95-6.35] umol/l increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2017-06-26",28371326,"Zhu Y","2017-03-30","J Cell Mol Med","www.ncbi.nlm.nih.gov/pubmed/28371326","Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.","Metabolic syndrome","862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls","5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.28,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,1.28,"[1.20-1.36]","Illumina [4642479] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2015-04-01",25027320,"Ramirez A","2014-07-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/25027320","SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.","Cerebrospinal AB1-42 levels in Alzheimer's disease dementia","363 European ancestry individuals","515 individuals","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-?","rs429358",0,429358,"missense_variant",0,0.442,{"v":4e-17,"d":"4.00E-17"},16.397940008672,null,0.4,"[0.30-0.50] unit decrease","Illumina [6812394] (imputed)","N"]
[10,"rs4299376",2,44072576,"rs4299376","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","2p21","ABCG5, ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs4299376-T","rs4299376",0,4299376,"intron_variant",0,0.684,{"v":5e-17,"d":"5.00E-17"},16.3010299956639,null,0.057,"[0.043-0.071] unit decrease","Affymetrix [7947838] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid p-Tau181p:AB1-42 ratio","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,null,{"v":5e-17,"d":"5.00E-17"},16.3010299956639,null,0.01178979,"[NR] unit decrease","Illumina [575353]","N"]
[14,"rs253412",5,75015242,"rs2112347","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","5q13.3","POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.629,{"v":6e-17,"d":"6.00E-17"},16.2218487496163,"(EA)",0.026,"[0.02-0.032] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.308,{"v":7e-17,"d":"7.00E-17"},16.1549019599857,"(Hispanic)",0.136,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.11,{"v":7e-17,"d":"7.00E-17"},16.1549019599857,"(Asian initial, BMI unadjusted)",0.117,"[0.09-0.144] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[38,"rs7970695",12,121424861,"rs7310409","2008-06-22",18439548,"Ridker PM","2008-04-24","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/18439548","Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.","C-reactive protein","6,345 European ancestry female individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs7310409-A","rs7310409",0,7310409,"intron_variant",0,"NR",{"v":7e-17,"d":"7.00E-17"},16.1549019599857,null,0.15,"[NR] mg/dl decrease","Illumina [336108]","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":8e-17,"d":"8.00E-17"},16.096910013008,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,"NR",{"v":8e-17,"d":"8.00E-17"},16.096910013008,null,0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.88,{"v":9e-17,"d":"9.00E-17"},16.0457574905606,"(Asian initial, BMI unadjusted)",0.11,"[0.085-0.135] unit increase","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[9,"rs1260326",2,27752463,"rs11127048","2017-10-17",28937693,"Clarke TK","2017-07-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28937693","Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).","Alcohol consumption","59,088 European ancestry females, 53,029 European ancestry males","NA","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,5912,7790,"rs11127048-G","rs11127048",0,11127048,"regulatory_region_variant",1,0.38,{"v":1e-16,"d":"1.00E-16"},16,"(women)",0.035,"[0.027-0.043] unit decrease","Affymetrix [12489781] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72863249,"rs13231516","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs13231516-T","rs13231516",0,13231516,"intron_variant",0,0.87,{"v":1e-16,"d":"1.00E-16"},16,null,0.03,"[0.022-0.038] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[35,"rs6589567",11,116670676,"rs6589567","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Triglyceride levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","11q23.3","ZNF259","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,7540,13244,"rs6589567-A","rs6589567",0,6589567,"intergenic_variant",1,0.23,{"v":1e-16,"d":"1.00E-16"},16,"(Indian)",13.09,"[9.99-16.19] unit increase","Illumina [551825]","N"]
[37,"rs4766578",12,112059557,"rs11065979","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test)","56,705 European ancestry heavy and light drinkers, 9,725 African American or Afro-Caribbean heavy and light drinkers, 1,789 Asian ancestry heavy and light drinkers, 4,812 Hispanic or Latin American heavy and light drinkers","42,077 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic ancestry heavy drinkers, 74,701 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers","12q24.12","BRAP","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.45,{"v":1e-16,"d":"1.00E-16"},16,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,"NR",{"v":1e-16,"d":"1.00E-16"},16,"(HDLC-WC)",0.29,"[0.23-0.35] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2015-09-22",25648963,"Debette S","2014-11-25","Biol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25648963","Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.","Verbal declarative memory","Up to 27,337 European ancestry individuals, up to 472 Korkulan individuals, up to 1,267 Erasmus Rucphen Family individuals","Up to 10,617 European ancestry individuals, up to 3,811 African American individuals","19q13.32","APOC1, APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.18,{"v":1e-16,"d":"1.00E-16"},16,"(PAR-dr, EA)",null,null,"Affymetrix, Illumina [NR] (imputed)","N"]
[57,"rs5754102",22,21917626,"rs131658","2019-03-26",28714469,"Langefeld CD","2017-07-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28714469","Transancestral mapping and genetic load in systemic lupus erythematosus.","Systemic lupus erythematosus","6,748 European ancestry cases, 11,516 European ancestry controls","NA","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs131658-G","rs131658",0,131658,"intron_variant",0,0.201,{"v":1e-16,"d":"1.00E-16"},16,null,1.25,"[1.19-1.32]","Illumina [at least 5000000] (imputed)","N"]
[58,"rs9616847",22,50877718,"rs5770908","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","22q13.33",null,"PPP6R2",null,null,"ENSG00000100239",null,null,"rs5770908-?","rs5770908",0,5770908,"intron_variant",0,"NR",{"v":1e-16,"d":"1.00E-16"},16,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[6,"rs199900492",1,234858597,"rs514230","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-A","rs514230",0,514230,"intergenic_variant",1,0.476,{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(EA)",0.038,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2017-07-06",28452372,"Gorski M","2017-04-28","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/28452372","1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.","Glomerular filtration rate (creatinine)","110,517 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.0081,"[0.0063-0.0099] unit increase","Affymetrix, Illumina [up to 10971307] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Alanine transaminase levels","134,182 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-?","rs2954029",0,2954029,"intron_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.03112,"[0.024-0.039] unit decrease","Illumina [6108953] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-A","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.41,"[0.31-0.51] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[42,"rs117427818",16,57015091,"rs5880","2015-01-30",24886709,"Ko A","2014-06-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/24886709","Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.","HDL cholesterol","3,701 Mexican ancestry individuals","5,114 Mexican ancestry individuals, 903 Mexican ancestry individuals from 73 dyslipidemic families","16q13","HERPUD1, CETP","CETP",null,null,"ENSG00000087237",null,null,"rs5880-C","rs5880",0,5880,"missense_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,null,0.29,"[NR] unit decrease","Illumina [1661241] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2013-09-27",23562540,"Cruchaga C","2013-04-04","Neuron","www.ncbi.nlm.nih.gov/pubmed/23562540","GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.","Alzheimer's disease biomarkers","591 European ancestry cases, 687 European ancestry controls",null,"19q13.32","APOE, TOMM40","APOE",null,null,"ENSG00000130203",null,null,"rs769449-A","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-16,"d":"2.00E-16"},15.698970004336,"(tau)",0.082,"[NR] unit increase","Illumina [5815690] (imputed)","N"]
[2,"rs2986164",1,25768937,"rs10903129","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p36.11","LDLRAP1","MACO1",null,null,"ENSG00000204178",null,null,"rs10903129-A","rs10903129",0,10903129,"intron_variant",0,0.463,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Trans-ethnic initial)",0.029,"[0.022-0.036] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[6,"rs199900492",1,234853268,"rs557933","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1q42.3","NR","AL160408.6",null,null,"ENSG00000282097",null,null,"rs557933-A","rs557933",0,557933,"intron_variant",0,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs56912706",5,75003678,"rs2307111","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.5474,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.023,"[0.018-0.028] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.061,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136154867,"rs495828","2012-08-15",22672568,"Heit JA","2012-06-05","J Thromb Haemost","www.ncbi.nlm.nih.gov/pubmed/22672568","A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.","Venous thromboembolism","1,503 European and other ancestry cases, 1,459 European and other ancestry controls","1,407 cases, 1,418 controls","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,0.272,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,1.65,"[1.46-1.86]","Illumina [~ 2500000] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglycerides","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.755,{"v":3e-16,"d":"3.00E-16"},15.5228787452803,"(Filipino)",0.342,"[0.26-0.42] unit decrease","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":3e-16,"d":"3.00E-16"},15.5228787452803,null,0.041,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21399216,"rs478442","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","2p24.1","NR","TDRD15 - AC067959.1","ENSG00000218819","ENSG00000271629",null,33072,22174,"rs478442-?","rs478442",0,478442,"regulatory_region_variant",1,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[23,"rs4921915",8,18272881,"rs1495741","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-G","rs1495741",0,1495741,"regulatory_region_variant",1,"NR",{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.039,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47457539,"rs11604680","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week) (MTAG)","up to 1,039,210 European ancestry individuals","NA","11p11.2","NR","PSMC3 - RAPSN","ENSG00000165916","ENSG00000165917",null,9515,1769,"rs11604680-G","rs11604680",0,11604680,"regulatory_region_variant",1,0.321,{"v":4e-16,"d":"4.00E-16"},15.397940008672,null,0.0115081,"[0.0087-0.0143] unit decrease","NR [~ 9732723] (imputed)","N"]
[41,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(EA)",0.043,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":4e-16,"d":"4.00E-16"},15.397940008672,"(KLRC3)",0.4164335,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[9,"rs1728918",2,27635463,"rs1728918","2013-02-12",23128233,"Jostins L","2012-11-01","Nature","www.ncbi.nlm.nih.gov/pubmed/23128233","Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.","Crohn's disease","Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls","Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls","2p23.3","UCN","PPM1G - NRBP1","ENSG00000115241","ENSG00000115216",null,2909,15194,"rs1728918-A","rs1728918",0,1728918,"regulatory_region_variant",1,0.299,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,1.123,"[1.086-1.16]","Affymetrix, Illumina [1230000] (imputed)","N"]
[17,"rs59136961",6,34603646,"rs2492863","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p21.31","C6orf106, SNRPC, UHRF1BP1","C6orf106",null,null,"ENSG00000196821",null,null,"rs2492863-A","rs2492863",0,2492863,"intron_variant",0,0.139616,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,null,0.02467,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[47,"rs80204526",18,47106028,"rs149615216","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs149615216-C","rs149615216",0,149615216,"intron_variant",0,0.987,{"v":5e-16,"d":"5.00E-16"},15.3010299956639,"(EA)",0.168,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18273300,"rs1495743","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","8p22","intergenic","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14572,111511,"rs1495743-?","rs1495743",0,1495743,"intergenic_variant",1,"NR",{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(1methylxanthine)",0.09426,"[NR] unit decrease","Affymetrix [655658]","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.564,{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(EA)",0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs2238681",19,45401666,"rs8106922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs8106922-A","rs8106922",0,8106922,"intron_variant",0,0.598,{"v":6e-16,"d":"6.00E-16"},15.2218487496163,"(EA)",0.039,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18272881,"rs1495741","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-G","rs1495741",0,1495741,"regulatory_region_variant",1,0.224,{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":7e-16,"d":"7.00E-16"},15.1549019599857,"(HDL-C.by.NMR, whole)",1.513,"[NR] unit decrease","Illumina [335603]","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":8e-16,"d":"8.00E-16"},15.096910013008,null,0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs10793624",10,46024729,"rs11239550","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Mean corpuscular hemoglobin","up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.","16,389 individuals of European and African American ancestry.","10q11.22","2008-03-01","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239550-?","rs11239550",0,11239550,"intron_variant",0,"NR",{"v":8e-16,"d":"8.00E-16"},15.096910013008,{"$nulls":3},"NR [2500000] (imputed)","N"]
[47,"rs9304381",18,47176261,"rs6507939","2017-02-24",27005778,"Kettunen J","2016-03-23","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/27005778","Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.","Metabolite levels (lipoprotein measures)","2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,50709,459,"rs6507939-C","rs6507939",0,6507939,"intergenic_variant",1,0.84,{"v":8e-16,"d":"8.00E-16"},15.096910013008,"(HDL diameter)",0.11,"[0.09-0.13] unit increase","Affymetrix, Illumina, Perlegen [12133295] (imputed)","N"]
[8,"rs668948",2,21288226,"rs563290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21281,58563,"rs563290-G","rs563290",0,563290,"intergenic_variant",1,0.178,{"v":1e-15,"d":"1.00E-15"},15,"(Hispanic)",0.156,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160575366,"rs11753995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs11753995-G","rs11753995",0,11753995,"intron_variant",0,0.836,{"v":1e-15,"d":"1.00E-15"},15,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160575366,"rs11753995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs11753995-G","rs11753995",0,11753995,"intron_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,null,0.047,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs112875651",8,126500031,"rs28601761","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Mean corpuscular hemoglobin","172,332 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-G","rs28601761",0,28601761,"intron_variant",0,0.4184,{"v":1e-15,"d":"1.00E-15"},15,null,0.02902436,"[0.022-0.036] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[34,"rs72997616",11,75473715,"rs1806895","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","11q13.5","NR","DGAT2, AP001922.1",null,null,"ENSG00000062282, ENSG00000247867",null,null,"rs1806895-T","rs1806895",0,1806895,"intron_variant",0,0.8558,{"v":1e-15,"d":"1.00E-15"},15,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[47,"rs62101776",18,47203408,"rs11874381","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or HDL-cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol)","NA","18q21.1","LIPG","SMUG1P1 - AC090227.2","ENSG00000267444","ENSG00000267674",null,25878,62785,"rs11874381-A","rs11874381",0,11874381,"intergenic_variant",1,"NR",{"v":1e-15,"d":"1.00E-15"},15,{"$nulls":3},"NR [2501543] (imputed)","N"]
[49,"rs58542926",19,19379549,"rs58542926","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-C","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":1e-15,"d":"1.00E-15"},15,null,0.067,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206172,"rs516246","2013-02-12",23128233,"Jostins L","2012-11-01","Nature","www.ncbi.nlm.nih.gov/pubmed/23128233","Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.","Crohn's disease","Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls","Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls","19q13.33","FUT2, SPHK2, IZUMO1, DBP","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-T","rs516246",0,516246,"intron_variant",0,0.483,{"v":1e-15,"d":"1.00E-15"},15,null,1.107,"[1.071-1.143]","Affymetrix, Illumina [1230000] (imputed)","N"]
[4,"rs6661669",1,63199936,"rs6679002","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","1p31.3","ANGPTL3","AC103923.1 - ATG4C","ENSG00000235545","ENSG00000125703",null,23571,49870,"rs6679002-T","rs6679002",0,6679002,"TF_binding_site_variant",1,0.59,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(X-03094)",0.014,"[0.01-0.018] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[15,"rs6882345",5,156479323,"rs1553318","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-C","rs1553318",0,1553318,"intron_variant",0,0.65,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.05,"[0.038-0.062] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160575366,"rs11753995","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs11753995-G","rs11753995",0,11753995,"intron_variant",0,"NR",{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.048,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs7973253",12,109879292,"rs11608355","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","12q24.11","UNG","MYO1H",null,null,"ENSG00000174527",null,null,"rs11608355-T","rs11608355",0,11608355,"intron_variant",0,0.316757,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,7.92,"z score decrease","NR [10847151] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.168,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(EA)",0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs11882123",19,19657632,"rs7245983","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Red cell distribution width","171,529 European ancestry individuals","NA","19p13.11","CILP2","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,164,14884,"rs7245983-C","rs7245983",0,7245983,"intergenic_variant",1,0.3445,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.02971055,"[0.022-0.037] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":2e-15,"d":"2.00E-15"},14.698970004336,null,0.15,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":2e-15,"d":"2.00E-15"},14.698970004336,"(Inactive peptidyl-prolyl cis-trans isomerase FKBP6, FKBP6.12529.32.3)",0.21,"[0.15-0.27] unit increase","Affymetrix [10572788] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.782,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(EA)",0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Triglycerides","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.356,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,"(Hispanic)",0.108,"[0.081-0.135] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[21,"rs2126259",8,9185146,"rs2126259","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-T","rs2126259",0,2126259,"intron_variant",0,"NR",{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.056,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112591686,"rs17630235","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.13","NR","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-G","rs17630235",0,17630235,"intergenic_variant",1,null,{"v":3e-15,"d":"3.00E-15"},14.5228787452803,null,0.292,"unit decrease","Affymetrix [at least 2696785] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.219,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",0.037,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs693",2,21232804,"rs1041968","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1041968-G","rs1041968",0,1041968,"synonymous_variant",0,0.511,{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58680954,"rs2043085","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs2043085-?","rs2043085",0,2043085,"intron_variant",0,"NR",{"v":4e-15,"d":"4.00E-15"},14.397940008672,"(EA)",1.1494253,null,"Illumina [12023830] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-G","rs629301",0,629301,"3_prime_UTR_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160564476,"rs662138","2018-09-12",23093944,"Krumsiek J","2012-10-18","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/23093944","Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.","Serum metabolite levels","1,678 European ancestry individuals","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs662138-?","rs662138",0,662138,"intron_variant",0,"NR",{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(isobutyrylcarnitine)",0.06786,"[NR] unit decrease","Affymetrix [655658]","N"]
[19,"6:160560880_CATG_C",6,160578860,"rs1564348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q25.3","NR","SLC22A1",null,null,"ENSG00000175003",null,null,"rs1564348-T","rs1564348",0,1564348,"intron_variant",0,0.838,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(EA)",0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.9,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(Hispanic)",0.198,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45424351,"rs814573","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,1745,5710,"rs814573-T","rs814573",0,814573,"intergenic_variant",1,0.198,{"v":5E-15,"d":"5.00E-15"},14.3010299956639,"(Apolipoprotein E (isoform E2), APOE.5312.49.3)",0.25,"[0.19-0.31] unit increase","Affymetrix [10572788] (imputed)","N"]
[29,"rs62568184",9,107648595,"rs3847302","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3847302-A","rs3847302",0,3847302,"intron_variant",0,"NR",{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.05,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[32,"rs10793624",10,45953767,"rs7908745","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Reticulocyte count","170,641 European ancestry individuals","NA","10q11.21","NR","2008-03-01",null,null,"ENSG00000165406",null,null,"rs7908745-G","rs7908745",0,7908745,"missense_variant",0,0.3143,{"v":6e-15,"d":"6.00E-15"},14.2218487496163,null,0.03014323,"[0.023-0.038] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[5,"rs3832016",1,109818306,"rs629301","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs629301-T","rs629301",0,629301,"3_prime_UTR_variant",0,0.776,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(Neogenin, NEO1.8900.28.3)",0.23,"[0.17-0.29] unit decrease","Affymetrix [10572788] (imputed)","N"]
[22,"rs1736070",8,11666451,"rs1616534","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8p23.1","FDFT1 ","FDFT1",null,null,"ENSG00000079459",null,null,"rs1616534-T","rs1616534",0,1616534,"intron_variant",0,0.6,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.033,"[0.025-0.041] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","HDL cholesterol","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-T","rs4939883",0,4939883,"intergenic_variant",1,0.17,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,null,0.14,"[0.10-0.18] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-T","rs10401969",0,10401969,"intron_variant",0,0.925,{"v":7e-15,"d":"7.00E-15"},14.1549019599857,"(EA)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","11q23.3","BUD13, ZPR1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.861,{"v":8e-15,"d":"8.00E-15"},14.096910013008,null,0.071,"[0.053-0.089] unit decrease","Affymetrix [7947838] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Lymphocyte percentage of white cells","171,748 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-G","rs2954021",0,2954021,"intron_variant",0,0.5053,{"v":9e-15,"d":"9.00E-15"},14.0457574905606,null,0.02756497,"[0.021-0.035] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-T","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.223,{"v":1E-14,"d":"1.00E-14"},14,"(Hemojuvelin, HFE2.3332.57.1)",0.23,"[0.17-0.29] unit decrease","Affymetrix [10572788] (imputed)","N"]
[8,"rs74410908",2,21250914,"rs679899","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","2p24.1","APOB","APOB",null,null,"ENSG00000084674",null,null,"rs679899-G","rs679899",0,679899,"missense_variant",0,0.503125,{"v":1E-14,"d":"1.00E-14"},14,"(KCNMB3)",0.18513301,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[12,"rs4690098",4,3446883,"rs3752442","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","4p16.3","HGFAC","HGFAC",null,null,"ENSG00000109758",null,null,"rs3752442-?","rs3752442",0,3752442,"intron_variant",0,"NR",{"v":1E-14,"d":"1.00E-14"},14,null,0.03353,"[0.025-0.042] unit decrease novel","Illumina [6108953] (imputed)","N"]
[35,"rs758044300",11,116574336,"rs1145198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,45368,44550,"rs1145198-G","rs1145198",0,1145198,"TF_binding_site_variant",1,0.751,{"v":1E-14,"d":"1.00E-14"},14,"(EA)",0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs2244608",12,121416650,"rs1169288","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-C","rs1169288",0,1169288,"missense_variant",0,0.33,{"v":1E-14,"d":"1.00E-14"},14,null,1.45,"[1.06-1.84] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[41,"rs1077835",15,58723479,"rs1077834","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs1077834-T","rs1077834",0,1077834,"intron_variant",0,0.49,{"v":1E-14,"d":"1.00E-14"},14,"(HDL)",0.14,"[0.1-0.18] unit decrease","Illumina [561583]","N"]
[50,"rs429358",19,45411941,"rs429358","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.84,{"v":1E-14,"d":"1.00E-14"},14,null,0.066,"[0.048-0.084] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":1E-14,"d":"1.00E-14"},14,"(Deformed epidermal autoregulatory factor 1 homolog, DEAF1.6369.82.3)",0.2,"[0.14-0.26] unit increase","Affymetrix [10572788] (imputed)","N"]
[21,"rs2976940",8,8236677,"rs2976958","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","SGK223","PRAG1",null,null,"ENSG00000275342",null,null,"rs2976958-C","rs2976958",0,2976958,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.013322,"[0.0099-0.0167] unit decrease","Affymetrix [18485882] (imputed)","N"]
[26,"rs35309034",8,126498828,"rs4870941","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-G","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.04,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.39,"[0.29-0.49] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke","34,217 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,146 African American controls, 222 Asian ancestry cases, 333 Asian ancestry controls, 555 Latin American cases, 692 Latin American controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[41,"rs1077835",15,58723426,"rs1077835","2013-08-02",23505323,"Weissglas-Volkov D","2013-03-15","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/23505323","Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.","HDL cholesterol","1,122 Mexican ancestry hypertriglyceridemia cases, 1,118 Mexican ancestry controls","1,067 Mexican ancestry hypertriglyceridemia cases, 1,054 Mexican ancestry controls","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1077835-A","rs1077835",0,1077835,"intron_variant",0,0.38,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,0.17,"[0.13-0.21] unit decrease","Illumina [1361436] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-?","rs7499892",0,7499892,"intron_variant",0,"NR",{"v":2E-14,"d":"2.00E-14"},13.698970004336,"(HDL.total, fasting)",0.742,"[NR] unit decrease","Illumina [335603]","N"]
[50,"rs429358",19,45410002,"rs769449","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cognitive impairment test score","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,null,{"v":2E-14,"d":"2.00E-14"},13.698970004336,null,3.677384,"[NR] unit decrease","Illumina [575353]","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.756,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(AA)",0.227,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum albumin level","Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.0124,"[0.0093-0.0155] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-11-25",26831199,"Pattaro C","2016-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26831199","Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.","Glomerular filtration rate (creatinine)","133,413 European ancestry individuals","42,166 European ancestry individuals, up to 16,471 African ancestry individuals, up to 42,296 Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.42,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.0068,"[0.005-0.0086] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[19,"6:160560880_CATG_C",6,160569068,"rs62440901","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","SLC22A1",null,null,"ENSG00000175003",null,null,"rs62440901-T","rs62440901",0,62440901,"intron_variant",0,null,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,2.05,"[1.26-2.84] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[29,"rs4149307",9,107591272,"rs2853579","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2853579-G","rs2853579",0,2853579,"synonymous_variant",0,0.874,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA)",0.052,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723675,"rs1800588","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.38,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,null,0.018,"[0.014-0.022] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[42,"rs3816117",16,56999328,"rs11508026","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or triglyceride levels (pleiotropy)","65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides)","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs11508026-T","rs11508026",0,11508026,"intron_variant",0,"NR",{"v":3e-14,"d":"3.00E-14"},13.5228787452803,{"$nulls":3},"NR [25015711] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","19q13.32","APOC1, CTB-129P6.7","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.1730382,{"v":3e-14,"d":"3.00E-14"},13.5228787452803,"(EA, Small nuclear ribonucleoprotein F)",0.4345,"[0.32-0.54] unit decrease","Affymetrix [509946]","N"]
[8,"rs668948",2,21294975,"rs541041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.174,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(Hispanic)",0.149,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs6601599",8,11433909,"rs2898290","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,null,{"v":4E-14,"d":"4.00E-14"},13.397940008672,null,0.294,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[23,"rs4921915",8,18272881,"rs1495741","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","8p22","NAT2","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-G","rs1495741",0,1495741,"regulatory_region_variant",1,0.22,{"v":4E-14,"d":"4.00E-14"},13.397940008672,null,2.97,"[2.15-3.79] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[37,"rs11066320",12,112072424,"rs11065987","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or ischemic stroke","12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls","NA","12q24.12","SH2B3","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-?","rs11065987",0,11065987,"intergenic_variant",1,null,{"v":4E-14,"d":"4.00E-14"},13.397940008672,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[50,"rs2238681",19,45408836,"rs405509","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","TOMM40",null,"ENSG00000130203",null,null,175,"rs405509-T","rs405509",0,405509,"regulatory_region_variant",0,0.49585,{"v":4E-14,"d":"4.00E-14"},13.397940008672,"(females)",1.596079,"[1.41-1.78]","Affymetrix, Illumina [2928658] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,"NR",{"v":5e-14,"d":"5.00E-14"},13.3010299956639,null,0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs199900492",1,234858597,"rs514230","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","1q42.3","IRF2BP2, TOMM20","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-A","rs514230",0,514230,"intergenic_variant",1,0.48,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,null,1.36,"[0.97-1.75] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2013-06-06",23419831,"Ramanan VK","2013-02-19","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/23419831","APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.","Alzheimer's disease biomarkers","555 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.28,{"v":5e-14,"d":"5.00E-14"},13.3010299956639,"(Cortical Ab)",null,null,"Illumina [6108668] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,0.183,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(Hispanic)",0.146,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-03-20",27588450,"Mahajan A","2016-09-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27588450","Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.","Glomerular filtration rate","23,553 European ancestry individuals, 23,536 Japanese individuals, 16,325 Hispanic individuals, 8,224 African American individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,null,0.872,"[0.65-1.1] unit decrease","Affymetrix, Illumina [at least 6581000] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,0.689,{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(AA)",0.177,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":6e-14,"d":"6.00E-14"},13.2218487496163,"(females)",1.6891578,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63090858,"rs6587980","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs6587980-C","rs6587980",0,6587980,"synonymous_variant",0,0.673,{"v":7e-14,"d":"7.00E-14"},13.1549019599857,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs2241212",12,109898732,"rs1558804","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","12q24.11","NR","KCTD10",null,null,"ENSG00000110906",null,null,"rs1558804-A","rs1558804",0,1558804,"intron_variant",0,"NR",{"v":7e-14,"d":"7.00E-14"},13.1549019599857,null,7.489,"z score decrease","Affymetrix [10847151] (imputed)","N"]
[50,"rs149214960",19,45329214,"rs10402271","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","BCAM","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-?","rs10402271",0,10402271,"regulatory_region_variant",1,"NR",{"v":7e-14,"d":"7.00E-14"},13.1549019599857,null,1.3904976,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[22,"rs11250098",8,10802146,"rs12546366","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (arm fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs12546366-T","rs12546366",0,12546366,"intron_variant",0,0.4529,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(females)",0.0212,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":8E-14,"d":"8.00E-14"},13.096910013008,"(APBB2)",0.37522233,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[19,"rs55730499",6,161010118,"rs10455872","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or large artery stroke","2,167 Large artery stroke cases, 22,233 Coronary artery disease cases, ~ 75,921 controls","NA","6q25.3","SLC22A3, LPAL2, LPA","LPA",null,null,"ENSG00000198670",null,null,"rs10455872-?","rs10455872",0,10455872,"intron_variant",0,null,{"v":9e-14,"d":"9.00E-14"},13.0457574905606,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[21,"rs615632",8,9803712,"rs13271489","2018-09-05",29455858,"Sung YJ","2018-02-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29455858","A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.","Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test)","14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers","48,198 European ancestry current smokers, 251,872 European ancestry former and never smokers, 1,971 African ancestry current smokers, 5,814 African ancestry former and never smokers, 29,485 Asian ancestry current smokers, 119,447 Asian ancestry former and never smokers, 3,737 Hispanic current smokers, 14,199 Hispanic former and never smokers","8p23.1","MIR124-1, MSRA","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,40836,104283,"rs13271489-?","rs13271489",0,13271489,"intergenic_variant",1,"NR",{"v":9e-14,"d":"9.00E-14"},13.0457574905606,"(EA)",null,null,"Affymetrix, Illumina [18800000] (imputed)","N"]
[49,"rs58542926",19,19379549,"rs58542926","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-?","rs58542926",0,58542926,"missense_variant",0,"NR",{"v":9e-14,"d":"9.00E-14"},13.0457574905606,null,0.06384,"[0.047-0.081] unit decrease novel","Illumina [6108953] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-04-30",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","Low density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","1p13.3","CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-G","rs646776",0,646776,"regulatory_region_variant",1,0.27,{"v":1E-13,"d":"1.00E-13"},13,"(Indian)",5.26,"[3.87-6.65] unit decrease","Illumina [551825]","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,0.177,{"v":1E-13,"d":"1.00E-13"},13,"(Hispanic)",0.145,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs3817588",2,27743154,"rs780092","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","Triglyceride levels","up to 33,431 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-G","rs780092",0,780092,"intron_variant",0,0.1428,{"v":1E-13,"d":"1.00E-13"},13,null,5.2217927,"[3.84-6.61] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[23,"rs4921915",8,18272881,"rs1495741","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-G","rs1495741",0,1495741,"regulatory_region_variant",1,0.224,{"v":1E-13,"d":"1.00E-13"},13,"(EA)",0.041,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47397353,"rs56030824","2019-03-28",30643251,"Liu M","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643251","Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.","Alcohol consumption (drinks per week)","up to 941,280 European ancestry individuals","NA","11p11.2","NR","SPI1",null,null,"ENSG00000066336",null,null,"rs56030824-A","rs56030824",0,56030824,"intron_variant",0,0.322,{"v":1E-13,"d":"1.00E-13"},13,null,0.011601888,"[0.0085-0.0147] unit decrease","NR [~ 10000000] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-?","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":1E-13,"d":"1.00E-13"},13,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs142042446",19,45395619,"rs2075650","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","19q13.32","NR","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":1E-13,"d":"1.00E-13"},13,null,0.027,"[NR] unit increase","Affymetrix [at least 28613428] (imputed)","N"]
[50,"rs75627662",19,45416178,"rs483082","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs483082-T","rs483082",0,483082,"non_coding_transcript_exon_variant",0,0.29,{"v":1E-13,"d":"1.00E-13"},13,null,0.11,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[57,"rs5754102",22,21982054,"rs1811069","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","22q11.21","NR","UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,3731,324,"rs1811069-T","rs1811069",0,1811069,"intergenic_variant",1,"NR",{"v":1E-13,"d":"1.00E-13"},13,null,0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.037,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs253412",5,75015242,"rs2112347","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","5q13.3","C5orf37","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.6252,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA, women)",0.0328,"[0.024-0.042] unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[25,"rs4876612",8,116799593,"rs800512","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","8q23.3",null,"TRPS1",null,null,"ENSG00000104447",null,null,"rs800512-?","rs800512",0,800512,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2018-12-17",26961502,"Wood AR","2016-03-10","Diabetologia","www.ncbi.nlm.nih.gov/pubmed/26961502","Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.","Body mass index","29,925 British ancestry cases, 89,763 British ancestry controls","NA","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,"NR",{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(additive model)",0.031,"[0.023-0.039] unit increase","NR [9288881] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","11q23.3","APOC3","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8775,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(NXPH2)",0.27592963,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[37,"rs4766578",12,111865049,"rs7310615","2016-10-05",26561523,"de Vries PS","2015-11-10","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/26561523","A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.","Fibrinogen levels","120,246 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3",null,null,"ENSG00000111252",null,null,"rs7310615-C","rs7310615",0,7310615,"intron_variant",0,0.5,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.0069,"NR unit decrease","Affymetrix, Illumina [~ 10700000] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.358,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(East Asian)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19460541,"rs73001065","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs73001065-G","rs73001065",0,73001065,"intron_variant",0,0.934,{"v":2e-13,"d":"2.00E-13"},12.698970004336,"(EA)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Logical memory (immediate recall)","305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","APOE, BCAM, PVRL2, TOMM40, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.25,{"v":2e-13,"d":"2.00E-13"},12.698970004336,null,0.36,"[0.26-0.46] unit decrease","Illumina [8066948] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62969402,"rs1168029","2012-02-28",22286219,"Kettunen J","2012-01-29","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22286219","Genome-wide association study identifies multiple loci influencing human serum metabolite levels.","Lipid metabolism phenotypes","8,330 European ancestry individuals","NA","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168029-?","rs1168029",0,1168029,"intron_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(MobCH)",0.13,"[0.091-0.169] unit increase","Illumina [~ 7700000] (imputed)","N"]
[16,"rs1235162",6,28793904,"rs3118359","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6p22.1","intergenic","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,42123,11742,"rs3118359-T","rs3118359",0,3118359,"intergenic_variant",1,0.0838,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.0378,"[0.028-0.048] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[22,"rs1736070",8,11664738,"rs1736060","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8p23.1","FDFT1","FDFT1",null,null,"ENSG00000079459",null,null,"rs1736060-T","rs1736060",0,1736060,"intron_variant",0,0.6,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(BMI-adjusted)",0.029,"[0.021-0.037] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.44,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Asian initial, BMI unadjusted)",0.064,"[0.046-0.082] unit increase","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2018-10-24",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","Triglyceride levels","1,017 Yoruban ancestry individuals, 1,765 Filipino individuals","188,577 European and other ancestry individuals","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(Filipino)",null,null,"Illumina [4454201] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-G","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(BP-HDLC)",0.29,"[0.21-0.37] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[50,"rs2238681",19,45410444,"rs769450","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs769450-G","rs769450",0,769450,"non_coding_transcript_exon_variant",0,0.614728,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,"(females)",1.604012,"[1.41-1.79]","Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs75627662",19,45418790,"rs5117","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOC1","APOC1",null,null,"ENSG00000130208",null,null,"rs5117-C","rs5117",0,5117,"intron_variant",0,0.28,{"v":3e-13,"d":"3.00E-13"},12.5228787452803,null,0.1,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[8,"rs668948",2,21428289,"rs71435601","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","2p24.1","NR","AC067959.1 - AC018742.1","ENSG00000271629","ENSG00000233005",null,6521,15758,"rs71435601-G","rs71435601",0,71435601,"intergenic_variant",1,0.133847,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,0.11650893,"[0.085-0.148] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[21,"rs615632",8,9804292,"rs9650622","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Diastolic blood pressure x alcohol consumption interaction (2df test)","63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers","238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","8p23.1","LOC105379235, MIR124-1","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,41416,103703,"rs9650622-T","rs9650622",0,9650622,"intergenic_variant",1,0.53,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.5177,{"v":4e-13,"d":"4.00E-13"},12.397940008672,null,0.0259686,"[0.019-0.033] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.654,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2014-11-13",24770881,"Nelson PT","2014-04-27","Acta Neuropathol","www.ncbi.nlm.nih.gov/pubmed/24770881","ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.","Alzheimer's disease","1443 cases and 99 controls","NA","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":4e-13,"d":"4.00E-13"},12.397940008672,{"$nulls":3},"NR [4913579] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":4e-13,"d":"4.00E-13"},12.397940008672,"(Leucine-rich repeat and transmembrane domain-containing protein 2, LRTM2.8906.60.3)",0.19,"[0.13-0.25] unit increase","Affymetrix [10572788] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-T","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.13,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.041,"[NR] unit increase","NR [NR] (imputed)","N"]
[22,"rs1692821",8,11702313,"rs709822","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Triglycerides","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs709822-C","rs709822",0,709822,"3_prime_UTR_variant",0,0.7117,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.0212,"[0.016-0.027] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","Cholesterol, total","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.248,{"v":5e-13,"d":"5.00E-13"},12.3010299956639,"(Hispanic)",0.103,"[0.076-0.13] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[35,"rs2072560",11,116660686,"rs2266788","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-C","rs2266788",0,2266788,"3_prime_UTR_variant",0,"NR",{"v":5e-13,"d":"5.00E-13"},12.3010299956639,null,0.39,"[0.29-0.49] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-03-01",23903356,"Hayes MG","2013-07-31","Diabetes","www.ncbi.nlm.nih.gov/pubmed/23903356","Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.","Glycemic traits (pregnancy)","1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean individuals, 1,178 Thai ancestry individuals","2,798 European ancestry individuals, 228 French Canadian founder population individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.409,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(FPG)",0.0044,"[NR] unit decrease","Illumina [up to 945994] (imputed)","N"]
[21,"rs615632",8,10190040,"rs7832708","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)","12,758 European ancestry heavy drinkers, 1,326 African American or Afro-Caribbean heavy drinkers, 648 Asian ancestry heavy drinkers, 364 Hispanic or Latin American heavy drinkers, 43,947 European ancestry light drinkers, 8,239 African American or Afro-Caribbean light drinkers, 1,141 Asian ancestry light drinkers, 4,448 Hispanic or Latin American light drinkers","42,078 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic heavy drinkers, 74,706 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs7832708-T","rs7832708",0,7832708,"intron_variant",0,0.49,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[50,"rs113914212",19,45302951,"rs2967668","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs2967668-?","rs2967668",0,2967668,"intron_variant",0,"NR",{"v":6e-13,"d":"6.00E-13"},12.2218487496163,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.03,{"v":6e-13,"d":"6.00E-13"},12.2218487496163,null,4.73,"[3.44-6.02] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[14,"rs7700719",5,74262162,"rs4703642","2017-02-25",27286809,"Ligthart S","2016-06-10","BMC Genomics","www.ncbi.nlm.nih.gov/pubmed/27286809","Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.","C-reactive protein levels or total cholesterol levels (pleiotropy)","65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol)","NA","5q13.3","GCNT4","AC116337.3",null,null,"ENSG00000249856",null,null,"rs4703642-A","rs4703642",0,4703642,"intron_variant",0,"NR",{"v":7e-13,"d":"7.00E-13"},12.1549019599857,{"$nulls":3},"NR [2501549] (imputed)","N"]
[14,"rs4704210",5,74604742,"rs6871667","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","LDL cholesterol","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","5q13.3","HMGCR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,72039,11238,"rs6871667-A","rs6871667",0,6871667,"intergenic_variant",1,0.55,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,2.014,"[1.47-2.56] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-T","rs651007",0,651007,"intergenic_variant",1,0.2261785,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(P-Selectin)",0.3726,"[0.27-0.47] unit decrease","Affymetrix [509946]","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity (ABCA-1 dependent assay)","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","11q23.3","APOA1/C3/A4/A5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.857,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,null,0.2019,"[0.15-0.26] unit increase","Illumina [at least 9000000] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,{"v":7e-13,"d":"7.00E-13"},12.1549019599857,"(Apolipoprotein L1, APOL1.9506.10.3)",0.18,"[0.12-0.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[17,"rs59136961",6,34581636,"rs2744971","2013-09-12",23563607,"Berndt SI","2013-04-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23563607","Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.","Height","8,097 European ancestry tall individuals, 8,099 European ancestry short individuals","4,872 European ancestry tall individuals, 4,831 European ancestry short individuals","6p21.31","C6orf106","C6orf106",null,null,"ENSG00000196821",null,null,"rs2744971-G","rs2744971",0,2744971,"intron_variant",0,0.15,{"v":8e-13,"d":"8.00E-13"},12.096910013008,null,1.26,"[NR]","Affymetrix, Illumina [~ 2800000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-12-14",30336701,"Sanchez-Roige S","2018-10-19","Am J Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30336701","Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.","Alcohol use disorder (total score)","141,932 European ancestry individuals","NA","2p23.3","SNX17, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,7.15,"[NR] z score decrease","NR [16213998]","N"]
[42,"rs3764261",16,56989590,"rs247616","2017-02-15",27587472,"Postmus I","2016-09-01","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/27587472","Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.","Response to statins (HDL cholesterol change)","16,769 European ancestry individuals","10,951 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.326,{"v":9E-13,"d":"9.00E-13"},12.0457574905606,null,0.0071,"[0.0090-0.0130] unit increase","Affymetrix, Illumina, Perlegen [up to 2500000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63118196,"rs10889353","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-?","rs10889353",0,10889353,"intron_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,"(VLDL.total, fasting)",2.688,"[NR] unit decrease","Illumina [335603]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-?","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,"(male)",0.25305,"[0.18-0.32] unit increase","Affymetrix [7794483] (imputed)","N"]
[16,"rs1235162",6,28796071,"rs116461399","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer","29,266 European ancestry cases, 56,450 European ancestry controls","NA","6p22.1","ZBED9, LINC01623","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,44290,9575,"rs116461399-C","rs116461399",1,3131337,"regulatory_region_variant",1,0.095879119,{"v":1e-12,"d":"1.00E-12"},12,null,1.1547382,"[1.109954181-1.20132906]","Illumina [10439017] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72856269,"rs2240466","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs2240466-G","rs2240466",0,2240466,"3_prime_UTR_variant",0,0.87,{"v":1e-12,"d":"1.00E-12"},12,null,0.14,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[21,"rs2976940",8,8258019,"rs2979151","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","SGK223","PRAG1 - AC103957.1","ENSG00000275342","ENSG00000253505",null,14011,13696,"rs2979151-G","rs2979151",0,2979151,"intergenic_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.01235,"[0.0089-0.0158] unit decrease","Affymetrix [18485882] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.087,{"v":1e-12,"d":"1.00E-12"},12,"(EA)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs1692821",8,11710369,"rs1293292","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1293292-G","rs1293292",0,1293292,"intron_variant",0,0.71921875,{"v":1e-12,"d":"1.00E-12"},12,"(GNS)",0.194467,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[36,"rs7973253",12,109874794,"rs10850137","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Neuroticism","449,484 European ancestry individuals","NA","12q24.11","NR","MYO1H",null,null,"ENSG00000174527",null,null,"rs10850137-C","rs10850137",0,10850137,"intron_variant",0,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,7.078,"z score decrease","Affymetrix [10847151] (imputed)","N"]
[42,"rs3764261",16,56987369,"rs56156922","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","16q13","HERPUD1, CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-?","rs56156922",0,56156922,"regulatory_region_variant",1,"NR",{"v":1e-12,"d":"1.00E-12"},12,null,0.03734,"[0.027-0.048] unit decrease novel","Illumina [6108953] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Triglycerides","96,598 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.45,{"v":1e-12,"d":"1.00E-12"},12,null,2.88,"[2.14-3.62] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,{"v":1e-12,"d":"1.00E-12"},12,"(Steroidogenic acute regulatory protein, mitochondrial, STAR.10085.25.3)",0.33,"[0.23-0.43] unit decrease","Affymetrix [10572788] (imputed)","N"]
[57,"rs5754102",22,21916272,"rs5754102","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754102-A","rs5754102",0,5754102,"intron_variant",0,0.1892,{"v":1e-12,"d":"1.00E-12"},12,null,0.027,"[0.02-0.034] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[8,"rs4564803",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21225281,"rs1042034","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1042034-C","rs1042034",0,1042034,"missense_variant",0,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.035,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Waist Circumference - Triglycerides (WC-TG)","22,161 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-A","rs780093",0,780093,"intron_variant",0,"NR",{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.19,"[0.13-0.25] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[14,"rs253412",5,75015242,"rs2112347","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Body mass index (joint analysis main effects and smoking interaction)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","5q13.3","C5orf37","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.6128,{"v":2E-12,"d":"2.00E-12"},11.698970004336,{"$nulls":3},"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72982874,"rs17145738","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","Triglycerides","8,684 European ancestry individuals","9,741 European ancestry individuals","7q11.23","MLXIPL","TBL2",null,null,"ENSG00000106638",null,null,"rs17145738-C","rs17145738",0,17145738,"3_prime_UTR_variant",0,0.84,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,8.21,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[21,"rs615632",8,9814411,"rs656319","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)","12,758 European ancestry heavy drinkers, 1,326 African American or Afro-Caribbean heavy drinkers, 648 Asian ancestry heavy drinkers, 364 Hispanic or Latin American heavy drinkers, 43,947 European ancestry light drinkers, 8,239 African American or Afro-Caribbean light drinkers, 1,141 Asian ancestry light drinkers, 4,448 Hispanic or Latin American light drinkers","42,078 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic heavy drinkers, 74,706 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers","8p23.1","LOC105379235, MIR124-1","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,51535,93584,"rs656319-A","rs656319",0,656319,"intergenic_variant",1,0.45,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[31,"rs117488242",10,5254847,"rs1832007","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Triglycerides","94,595 European ancestry individuals","93,982 European ancestry individuals","10p15.1","AKR1C4","AKR1C4",null,null,"ENSG00000198610",null,null,"rs1832007-G","rs1832007",0,1832007,"intron_variant",0,0.18,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.033,"[NR] mg/dL decrease","NR [NR] (imputed)","N"]
[37,"rs4766578",12,112059557,"rs11065979","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (combined parental attained age, Martingale residuals)","389,166 British ancestry individuals","NA","12q24.12","NR","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-C","rs11065979",0,11065979,"intergenic_variant",1,0.562141,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.0158643,"[0.011-0.02] unit decrease","Affymetrix [11535925] (imputed)","N"]
[41,"rs1601935",15,58674695,"rs4775041","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775041-G","rs4775041",0,4775041,"intron_variant",0,0.792,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(East Asian)",0.116,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58730498,"rs588136","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","15q21.3","LIPC","LIPC-AS1, ALDH1A2, LIPC",null,null,"ENSG00000259293, ENSG00000128918, ENSG00000166035",null,null,"rs588136-?","rs588136",0,588136,"intron_variant",0,0.69,{"v":2E-12,"d":"2.00E-12"},11.698970004336,"(HDL-C)",0.05,"[0.030-0.070] unit decrease","Affymetrix [~ 3700000] (imputed)","N"]
[50,"rs142042446",19,45388130,"rs34342646","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs34342646-A","rs34342646",0,34342646,"intron_variant",0,0.13,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,0.17,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[57,"rs5754102",22,21973319,"rs4821116","2014-04-15",24162738,"Hu Z","2013-10-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24162738","New loci associated with chronic hepatitis B virus infection in Han Chinese.","Hepatitis B","951 Han Chinese ancestry HBV carrier cases, 937 Han Chinese ancestry HBV cleared controls","4,230 Chinese ancestry HBV carrier cases, 3,051 Chinese ancestry HBV cleared controls, 2,622 Chinese ancestry controls","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs4821116-G","rs4821116",0,4821116,"intron_variant",0,0.59,{"v":2E-12,"d":"2.00E-12"},11.698970004336,null,1.2195,"[1.15-1.3]","Illumina [490610]","N"]
[16,"rs1235162",6,28934352,"rs148696809","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer","29,266 European ancestry cases, 56,450 European ancestry controls","NA","6p22.1","LINC01556, ZNF311","LINC01556 - KRT18P1","ENSG00000231041","ENSG00000226462",null,22038,2555,"rs148696809-C","rs148696809",0,148696809,"intergenic_variant",1,0.086604881,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,1.1571189,"[1.11078617-1.205384399]","Illumina [10439017] (imputed)","N"]
[19,"rs55730499",6,160997118,"rs74617384","2018-10-16",30003307,"Fall T","2018-07-12","Diabetologia","www.ncbi.nlm.nih.gov/pubmed/30003307","Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.","Coronary artery disease in diabetes","3,968 British ancestry cases, 11,698 British ancestry controls","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-T","rs74617384",0,74617384,"intron_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,1.38,"[1.26-1.51]","Affymetrix [9087334] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.087,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(EA)",0.058,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Waist-hip ratio","approximately 458,000 European ancestry individuals","NA","9q31.1",null,"ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-?","rs1883025",0,1883025,"intron_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2012-05-25",22493691,"Eriksson N","2012-04-06","PLoS One","www.ncbi.nlm.nih.gov/pubmed/22493691","Novel associations for hypothyroidism include known autoimmune risk loci.","Hypothyroidism","3,736 European ancestry cases, 35,546 European ancestry controls","NA","12q24.12","SH2B3, ATXN2, LOC100101246, BRAP, NAA25, C12orf51, PTPN11","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.502,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,1.2,"[1.14-1.27]","Illumina [870065]","N"]
[37,"rs565349424",12,112211833,"rs2238151","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","12q24.12","ALDH2","ALDH2, AC002996.1",null,null,"ENSG00000111275, ENSG00000257767",null,null,"rs2238151-C","rs2238151",0,2238151,"intron_variant",0,0.412078433433247,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,null,0.3507814,"[0.25-0.45] unit decrease","Illumina [247039]","N"]
[41,"rs261290",15,58678512,"rs10468017","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs10468017-T","rs10468017",0,10468017,"intron_variant",0,0.33,{"v":3e-12,"d":"3.00E-12"},11.5228787452803,"(HDL)",0.104,"[0.075-0.133] mmol/l increase","Illumina [NR] (imputed)","N"]
[50,"rs157580",19,45409167,"rs440446","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Eosinophil counts","approximately 440,000 European ancestry individuals","NA","19q13.32",null,"APOE",null,null,"ENSG00000130203",null,null,"rs440446-?","rs440446",0,440446,"missense_variant",0,"NR",{"v":3e-12,"d":"3.00E-12"},11.5228787452803,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Palmitoleic acid (16:1n-7) levels","3,521 Chinese ancestry individuals, European individuals (see Wu 2013).","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.019,"[0.013-0.025] unit increase","Affymetrix, Illumina [~ 2200000] (imputed)","N"]
[11,"rs3770586",2,169830155,"rs2287623","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","2q31.1","ABCB11","ABCB11, ABCB11",null,null,"ENSG00000073734, ENSG00000276582",null,null,"rs2287623-G","rs2287623",0,2287623,"intron_variant",0,0.41,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.027,"[NR] unit increase","NR [NR] (imputed)","N"]
[16,"rs1235162",6,29148394,"rs116826541","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer","29,266 European ancestry cases, 56,450 European ancestry controls","NA","6p22.1","OR2J2, OR14J1","OR2J2 - OR2J4P","ENSG00000226000","ENSG00000218297",null,4806,893,"rs116826541-G","rs116826541",1,3116815,"intergenic_variant",1,0.089874005,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,1.1556115,"[1.109395824-1.203752579]","Illumina [10439017] (imputed)","N"]
[25,"rs4876612",8,116719898,"rs800534","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hair color","approximately 452,000 European ancestry individuals","NA","8q23.3",null,"TRPS1",null,null,"ENSG00000104447",null,null,"rs800534-?","rs800534",0,800534,"intron_variant",0,"NR",{"v":4e-12,"d":"4.00E-12"},11.397940008672,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs2244608",12,121420807,"rs1183910","2014-01-10",23844046,"Dorajoo R","2013-07-02","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23844046","Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?","C-reactive protein","2,179 Chinese ancestry individuals, 2,275 Malay ancestry individuals, 2,238 Asian Indian ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs1183910-G","rs1183910",0,1183910,"intron_variant",0,0.709,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.054,"[NR] unit increase","Illumina [up to 1745429] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.686,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.1466,"[0.11-0.19] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[57,"rs5754102",22,21974703,"rs5754387","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754387-G","rs5754387",0,5754387,"intron_variant",0,0.806049,{"v":4e-12,"d":"4.00E-12"},11.397940008672,null,0.0162822,"[0.012-0.021] unit increase","NR [13737936] (imputed)","N"]
[22,"rs11250098",8,10789493,"rs4841460","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs4841460-C","rs4841460",0,4841460,"intron_variant",0,"NR",{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,0.012012,"[0.0086-0.0154] unit increase","Affymetrix [18485882] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.231,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,"(Hispanic)",0.121,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs473172",11,116762028,"rs12285074","2018-10-19",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (years of education)","up to 1,131,881 European ancestry individuals","NA","11q23.3",null,"SIK3",null,null,"ENSG00000160584",null,null,"rs12285074-A","rs12285074",0,12285074,"intron_variant",0,0.1012,{"v":5e-12,"d":"5.00E-12"},11.3010299956639,null,0.0161,"[0.012-0.021] unit increase","Affymetrix, Illumina [10000000] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2015-09-24",25282103,"Wood AR","2014-10-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25282103","Defining the role of common variation in the genomic and biological architecture of adult human height.","Height","253,288 European ancestry individuals","80,067 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.386,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,null,0.021,"[0.015-0.027] unit decrease","Affymetrix, Illumina, Perlegen [2550858] (imputed)","N"]
[22,"rs1692821",8,11707174,"rs2740594","2017-10-24",28892059,"Chang D","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892059","A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.","Parkinson's disease","20,184 European ancestry cases, 397,324 European ancestry controls","5,851 European ancestry cases, 5,866 European ancestry controls","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs2740594-A","rs2740594",0,2740594,"intron_variant",0,0.753,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,null,1.09,"[1.07-1.12]","Illumina [11933700] (imputed)","N"]
[48,"rs56322906",19,11341029,"rs1865063","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","19p13.2","ANGPTL8","DOCK6",null,null,"ENSG00000130158",null,null,"rs1865063-T","rs1865063",0,1865063,"intron_variant",0,0.26,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(BMI adjusted)",0.0632,"[0.046-0.08] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[49,"rs11882123",19,19545696,"rs2965183","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","19p13.11","GATAD2A, MIR640","GATAD2A",null,null,"ENSG00000167491",null,null,"rs2965183-A","rs2965183",0,2965183,"intron_variant",0,0.35,{"v":6e-12,"d":"6.00E-12"},11.2218487496163,"(EA)",1.04,"[1.02-1.06] (Oncoarray)","Illumina [~ 11800000] (imputed)","N"]
[21,"rs2126259",8,9185146,"rs2126259","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2126259-A","rs2126259",0,2126259,"intron_variant",0,0.13,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,0.02,"[0.01-0.03] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[38,"rs2244608",12,121416650,"rs1169288","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.31","NR","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-A","rs1169288",0,1169288,"missense_variant",0,0.669,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,"(EA)",0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49214274,"rs281379","2012-10-19",21102463,"Franke A","2010-11-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21102463","Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.","Crohn's disease","6,333 European ancestry cases, 15,056 European ancestry controls","15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios","19q13.33","FUT2, RASIP1","FUT2 - MAMSTR","ENSG00000176920","ENSG00000176909",null,5067,1725,"rs281379-A","rs281379",0,281379,"intergenic_variant",1,0.487,{"v":7e-12,"d":"7.00E-12"},11.1549019599857,null,1.07,"[1.04-1.11]","Affymetrix, Illumina [953241] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049819,"rs12042319","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Triglycerides","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs12042319-G","rs12042319",0,12042319,"3_prime_UTR_variant",0,0.81,{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,0.02,"[0.014-0.026] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[22,"rs10903342",8,11589042,"rs34421088","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","GATA4","GATA4",null,null,"ENSG00000136574",null,null,"rs34421088-A","rs34421088",0,34421088,"intron_variant",0,"NR",{"v":8e-12,"d":"8.00E-12"},11.096910013008,null,0.011995,"[0.0086-0.0154] unit increase","Affymetrix [18485882] (imputed)","N"]
[38,"rs7970695",12,121438844,"rs735396","2017-12-11",21908519,"Huffman JE","2011-12-15","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/21908519","Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.","N-glycan levels","Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals","NA","12q24.31","HNF1A, C12orf43, OASL","HNF1A, C12orf43",null,null,"ENSG00000135100, ENSG00000157895",null,null,"rs735396-G","rs735396",0,735396,"3_prime_UTR_variant",0,0.39,{"v":8e-12,"d":"8.00E-12"},11.096910013008,"(DG7)",0.1848085,"[0.13-0.24] (zscore) decrease","Illumina [NR]","N"]
[6,"rs199900492",1,234858597,"rs514230","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","1q42.3","IRF2BP2, TOMM20","AL160408.6 - LINC01132","ENSG00000282097","ENSG00000227630",null,2630,1192,"rs514230-A","rs514230",0,514230,"intergenic_variant",1,0.48,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,1.13,"[0.78-1.48] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[8,"rs4564803",2,21208211,"rs7557067","2009-01-12",19060906,"Kathiresan S","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060906","Common variants at 30 loci contribute to polygenic dyslipidemia.","Triglycerides","19,840 European ancestry individuals","Up to 20,623 European ancestry individuals","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,123678,13974,"rs7557067-G","rs7557067",0,7557067,"intergenic_variant",1,0.22,{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,0.08,"[0.04-0.12] s.d. decrease","Affymetrix, Illumina [~ 2600000] (imputed)","N"]
[14,"rs4704210",5,74625487,"rs7703051","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-?","rs7703051",0,7703051,"intron_variant",0,"NR",{"v":9e-12,"d":"9.00E-12"},11.0457574905606,{"$nulls":3},"Affymetrix [NR]","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":9e-12,"d":"9.00E-12"},11.0457574905606,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Cardiovascular disease","approximately 459,000 European ancestry individuals","NA","1p32.3",null,"PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-?","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[8,"rs4564803",2,21237544,"rs673548","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs673548-G","rs673548",0,673548,"intron_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[12,"rs6818397",4,3434885,"rs6818397","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","4p16.3","LRPAP1","RGS12",null,null,"ENSG00000159788",null,null,"rs6818397-T","rs6818397",0,6818397,"intron_variant",0,0.413,{"v":1e-11,"d":"1.00E-11"},11,"(Trans-ethnic initial)",0.0254,"[0.018-0.033] unit increase (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[16,"rs1235162",6,28796071,"rs116461399","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Squamous cell lung carcinoma","7,426 European ancestry cases, 55,627 European ancestry controls","NA","6p22.1","ZBED9, LINC01623","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,44290,9575,"rs116461399-C","rs116461399",1,3131337,"regulatory_region_variant",1,0.097015006,{"v":1e-11,"d":"1.00E-11"},11,null,1.2472361,"[1.170241522-1.329296602]","Illumina [10439017] (imputed)","N"]
[30,"rs115478735",9,136154867,"rs495828","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,0.28,{"v":1e-11,"d":"1.00E-11"},11,"(Hb)",0.089,"[0.064-0.114] unit decrease","Illumina [561583]","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-T","rs635634",0,635634,"regulatory_region_variant",1,0.18,{"v":1e-11,"d":"1.00E-11"},11,"(Insulin-like growth factor 1 receptor, IGF1R.4232.19.2)",0.22,"[0.16-0.28] unit decrease","Affymetrix [10572788] (imputed)","N"]
[33,"11:47650138_AT_A",11,47796062,"rs11039389","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","11p11.2","intergenic","FNBP4 - NUP160","ENSG00000109920","ENSG00000030066",null,7067,3577,"rs11039389-T","rs11039389",0,11039389,"intergenic_variant",1,0.65857,{"v":1e-11,"d":"1.00E-11"},11,null,6.781,"z score increase","Illumina [18485882] (imputed)","N"]
[37,"rs11066320",12,112072424,"rs11065987","2009-11-03",19862010,"Ganesh SK","2009-10-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19862010","Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.","Hemoglobin","24,167 European ancestry individuals","9,456 European ancestry individuals","12q24.12","TRAFD1","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-A","rs11065987",0,11065987,"intergenic_variant",1,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.06,"[0.04-0.08] g/dl increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.5,{"v":1e-11,"d":"1.00E-11"},11,"(X-12038)",0.013,"[0.0091-0.0169] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[48,"rs142158911",19,11202306,"rs6511720","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","LDLR",null,null,"ENSG00000130164",null,null,"rs6511720-G","rs6511720",0,6511720,"intron_variant",0,0.869,{"v":1e-11,"d":"1.00E-11"},11,"(AA)",0.255,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45426792,"rs141622900","2019-02-12",30369316,"Low-Kam C","2018-08-01","J Am Heart Assoc","www.ncbi.nlm.nih.gov/pubmed/30369316","Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.","Cholesterol efflux capacity (BHK stimulated assay)","3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls","NA","19q13.32","APOE/C1/C2/C4","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,4186,3269,"rs141622900-G","rs141622900",0,141622900,"intergenic_variant",1,0.942,{"v":1e-11,"d":"1.00E-11"},11,null,0.2833,"[0.20-0.37] unit decrease","Illumina [at least 9000000] (imputed)","N"]
[55,"rs6129762",20,39811275,"rs4297946","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","PLCG1, ZHX3",null,null,"ENSG00000124181, ENSG00000174306",null,null,"rs4297946-G","rs4297946",0,4297946,"3_prime_UTR_variant",0,"NR",{"v":1e-11,"d":"1.00E-11"},11,null,0.03,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[6,"rs199900492",1,234853268,"rs557933","2018-07-30",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Total cholesterol levels","128,305 Japanese ancestry individuals","NA","1q42.3","LOC101927787, LINC01132","AL160408.6",null,null,"ENSG00000282097",null,null,"rs557933-?","rs557933",0,557933,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.02899,"[0.021-0.037] unit increase novel","Illumina [6108953] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,0.196,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(Hispanic)",0.128,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[15,"rs6882345",5,156479323,"rs1553318","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Triglycerides","up to 62,166 European ancestry individuals","NA","5q33.3","TIMD4, HAVCR1","HAVCR1",null,null,"ENSG00000113249",null,null,"rs1553318-C","rs1553318",0,1553318,"intron_variant",0,0.65,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.042,"[0.03-0.054] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[24,"rs2326077",8,59392324,"rs9297994","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","8q12.1","CYP7A1","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,28264,10413,"rs9297994-G","rs9297994",0,9297994,"intergenic_variant",1,0.34,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.042,"[0.03-0.054] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[26,"rs112875651",8,126500031,"rs28601761","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs28601761-C","rs28601761",0,28601761,"intron_variant",0,0.57,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(BMI-adjusted)",0.026,"[0.018-0.034] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.255,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.0279,"[0.02-0.036] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[33,"11:47650138_AT_A",11,47807774,"rs2290850","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Positive affect","410,603 European ancestry individuals","NA","11p11.2","NR","NUP160",null,null,"ENSG00000030066",null,null,"rs2290850-C","rs2290850",0,2290850,"intron_variant",0,0.3482479222397,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.008333924,"[0.0059-0.0108] unit decrease","NR [NR]","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.495,{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA)",0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3213545",12,121443116,"rs1169314","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.31","NR","C12orf43",null,null,"ENSG00000157895",null,null,"rs1169314-A","rs1169314",0,1169314,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs1077835",15,58723939,"rs2070895","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs2070895-?","rs2070895",0,2070895,"intron_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,"(EA)",1.1494253,null,"Illumina [12023830] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","HDL cholesterol","20,697 European ancestry individuals, 715 Orcadian individuals","NA","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-G","rs4939883",0,4939883,"intergenic_variant",1,0.83,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.1,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[49,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.01434,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte count","169,822 European ancestry individuals","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.0314,{"v":2e-11,"d":"2.00E-11"},10.698970004336,null,0.06908321,"[0.049-0.089] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Type 2 diabetes","approximately 459,000 European ancestry individuals","NA","20q13.12",null,"HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-?","rs1800961",0,1800961,"missense_variant",0,"NR",{"v":2e-11,"d":"2.00E-11"},10.698970004336,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[12,"rs59950280",4,3452345,"rs59950280","2017-06-01",28107422,"de Vries PS","2017-01-20","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28107422","Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.","Fibrinogen levels","91,953 European ancestry individuals (imputed to 1000 Genomes)",null,"4p16.3","HGFAC, DOK7","HGFAC - DOK7","ENSG00000109758","ENSG00000175920",null,1123,12693,"rs59950280-?","rs59950280",0,59950280,"intergenic_variant",1,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.008,"unit increase","Affymetrix, Illumina [10883314] (imputed)","N"]
[24,"rs2326077",8,59393273,"rs4738684","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","8q12.1","CYP7A1","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,29213,9464,"rs4738684-A","rs4738684",0,4738684,"regulatory_region_variant",1,0.34,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.041,"[0.029-0.053] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[35,"rs11820589",11,116626258,"rs11825181","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","11q23.3","APOA5","BUD13",null,null,"ENSG00000137656",null,null,"rs11825181-A","rs11825181",0,11825181,"intron_variant",0,0.08,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(1-linoleoylglycerol (1-monolinolein))",0.076,"[0.054-0.098] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","High light scatter reticulocyte percentage of red cells","170,763 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8665,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.03503236,"[0.025-0.045] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[37,"rs11066320",12,112273499,"rs11513729","2017-05-12",27997041,"Traylor M","2016-12-20","Ann Neurol","www.ncbi.nlm.nih.gov/pubmed/27997041","Genetic variation at 16q24.2 is associated with small vessel stroke.","Ischemic stroke","10,210 European ancestry cases, 12,285 European ancestry controls","7,743 European ancestry cases, 17,970 European ancestry controls","12q24.12","NR","ALDH2 - MAPKAPK5-AS1","ENSG00000111275","ENSG00000234608",null,18166,4069,"rs11513729-?","rs11513729",0,11513729,"intergenic_variant",1,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,6.63,"z score increase","Affymetrix, Illumina [NR] (imputed)","N"]
[48,"rs12052200",19,11163601,"rs1122608","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease","33,398 cases, 75,726 controls","NA","19p13.2","LDLR, SMARCA4","SMARCA4",null,null,"ENSG00000127616",null,null,"rs1122608-?","rs1122608",0,1122608,"intron_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,1.1364,"[1.09-1.18]","Illumina [575000] (imputed)","N"]
[51,"rs35106244",19,49206674,"rs601338","2014-12-10",24816252,"Shin SY","2014-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24816252","An atlas of genetic influences on human blood metabolites.","Blood metabolite levels","7,824 European ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs601338-A","rs601338",0,601338,"stop_gained",0,0.43,{"v":3E-11,"d":"3.00E-11"},10.5228787452803,"(ADpSGEGDFXAEGGGVR)",0.041,"[0.029-0.053] unit increase","Affymetrix, Illumina [2100000] (imputed)","N"]
[55,"rs6129762",20,39672618,"rs6029526","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","TOP1",null,null,"ENSG00000198900",null,null,"rs6029526-T","rs6029526",0,6029526,"intron_variant",0,"NR",{"v":3E-11,"d":"3.00E-11"},10.5228787452803,null,0.029,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817590,"rs12740374","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs12740374-G","rs12740374",0,12740374,"3_prime_UTR_variant",0,0.756,{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(AA)",0.196,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs9295128",6,160751531,"rs9295128","2017-11-20",28753643,"Yeo A","2017-07-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/28753643","Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.","Lipoprotein phospholipase A2 activity in cardiovascular disease","22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry","NA","6q25.3","intergenic","SLC22A2 - SLC22A3","ENSG00000112499","ENSG00000146477",null,52861,17769,"rs9295128-T","rs9295128",0,9295128,"intergenic_variant",1,0.01694,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,11.72,"[8.25-15.19] (nmol/min/ml) increase","Affymetrix, Illumina [13572687] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Red blood cell count","up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.","16,389 individuals of European and African American ancestry.","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,"(Asian)",8.6E-3,"[0.0061-0.0111] unit increase","NR [2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47915299,"rs34467936","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Depressed affect","357,957 European ancestry individuals","NA","11p11.2","NR","NUP160 - AC023232.1","ENSG00000030066","ENSG00000254780",null,45192,11576,"rs34467936G","rs34467936",0,34467936,"intergenic_variant",1,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.01605,"[0.011-0.021] unit decrease","Affymetrix [10847151] (imputed)","N"]
[35,"11:116999722_TA_T",11,117023487,"rs7128382","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Systolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","11q23.3","PAFAH1B2","PAFAH1B2",null,null,"ENSG00000168092",null,null,"rs7128382-A","rs7128382",0,7128382,"intron_variant",0,0.2123,{"v":4e-11,"d":"4.00E-11"},10.397940008672,null,0.2688,"[0.19-0.35] mmHg increase","Affymetrix [NR] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","19p13.11","NR","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-?","rs10401969",0,10401969,"intron_variant",0,"NR",{"v":4e-11,"d":"4.00E-11"},10.397940008672,{"$nulls":3},"Affymetrix [NR]","N"]
[3,"rs11591147",1,55505647,"rs11591147","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,"NR",{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.458,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.334,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(AA)",0.178,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs4876611",8,116663898,"rs2737252","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q23.3","NR","TRPS1",null,null,"ENSG00000104447",null,null,"rs2737252-G","rs2737252",0,2737252,"intron_variant",0,"NR",{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-?","rs3817334",0,3817334,"intron_variant",0,"NR",{"v":5e-11,"d":"5.00E-11"},10.3010299956639,{"$nulls":3},"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[36,"rs7973253",12,109879292,"rs11608355","2018-02-01",29255261,"Luciano M","2017-12-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29255261","Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.","Neuroticism","329,821 European ancestry individuals","122,867 European ancestry individuals","12q24.11","intergenic","MYO1H",null,null,"ENSG00000174527",null,null,"rs11608355-T","rs11608355",0,11608355,"intron_variant",0,0.68324,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,null,6.557,"z score decrease","Illumina [18485882] (imputed)","N"]
[42,"rs193695",16,56985139,"rs9989419","2014-03-22",24023261,"Keller M","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023261","THOC5: a novel gene involved in HDL-cholesterol metabolism.","Lipid traits","839 European ancestry individuals","up to 5,248 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,0.42,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(HDL-C)",6.57,"unit decrease","Affymetrix [390619]","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":5e-11,"d":"5.00E-11"},10.3010299956639,"(LRP1B)",0.32986814,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2014-03-01",23903356,"Hayes MG","2013-07-31","Diabetes","www.ncbi.nlm.nih.gov/pubmed/23903356","Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.","Glycemic traits (pregnancy)","1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean individuals, 1,178 Thai ancestry individuals","2,798 European ancestry individuals, 228 French Canadian founder population individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.409,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,"(FCP)",0.0116,"[NR] unit decrease","Illumina [up to 945994] (imputed)","N"]
[22,"rs4240674",8,10846709,"rs4841468","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs4841468-C","rs4841468",0,4841468,"intron_variant",0,"NR",{"v":6E-11,"d":"6.00E-11"},10.2218487496163,null,0.011342,"[0.0079-0.0147] unit increase","Affymetrix [18485882] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":6E-11,"d":"6.00E-11"},10.2218487496163,{"$nulls":3},"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-12-06",23603763,"Liu JZ","2013-06-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23603763","Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.","Primary sclerosing cholangitis","3,789 European ancestry cases, 25,079 European ancestry controls","NA","12q24.12","SH2B3, ATXN2","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-A","rs3184504",0,3184504,"missense_variant",0,0.488,{"v":6E-11,"d":"6.00E-11"},10.2218487496163,null,1.18,"[1.12-1.24]","Illumina [140322] (imputed)","N"]
[9,"rs74175068",2,27840640,"rs4666002","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","2p23.3","GCKR","ZNF512, AC074091.1",null,null,"ENSG00000243943, ENSG00000259080",null,null,"rs4666002-?","rs4666002",0,4666002,"intron_variant",0,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(levels)",0,"[1.10-0.70] % increase","Illumina [NR] (imputed)","N"]
[32,"rs10793624",10,46202429,"rs35267807","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red blood cell count","approximately 445,000 European ancestry individuals","NA","10q11.22",null,"FAM21FP",null,null,"ENSG00000237840",null,null,"rs35267807-?","rs35267807",0,35267807,"intron_variant",0,"NR",{"v":7e-11,"d":"7.00E-11"},10.1549019599857,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[38,"rs3213545",12,121450165,"rs2264750","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","12q24.31","HNF1A","C12orf43",null,null,"ENSG00000157895",null,null,"rs2264750-T","rs2264750",0,2264750,"intron_variant",0,0.3,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,null,0.042,"[0.03-0.054] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2013-03-19",23222517,"van der Harst P","2012-12-05","Nature","www.ncbi.nlm.nih.gov/pubmed/23222517","Seventy-five genetic loci influencing the human red blood cell.","Red blood cell traits","62,553 European ancestry individuals, 9,308 South Asian ancestry individuals","63,506 European ancestry individuals","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":7e-11,"d":"7.00E-11"},10.1549019599857,"(Hgb)",0.034,"[0.022-0.046] unit increase","Affymetrix, Illumina, Perlegen [2711806] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2015-04-24",21239051,"Reilly MP","2011-01-14","Lancet","www.ncbi.nlm.nih.gov/pubmed/21239051","Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.","Coronary artery disease","1,808 European ancestry cases, 915 European ancestry controls","10,585 European ancestry cases, 6,468 European ancestry controls","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,0.79,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,1.33,"[1.22-1.44]","Affymetrix, Illumina [> 2400000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47669175,"rs59360790","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Body fat percentage","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","11p11.2","NR","MTCH2 - AGBL2","ENSG00000109919","ENSG00000165923",null,5000,11968,"rs59360790-?","rs59360790",0,59360790,"intergenic_variant",1,"NR",{"v":8e-11,"d":"8.00E-11"},10.096910013008,"(male)",0.17158,"[0.12-0.22] unit increase","Affymetrix [7794483] (imputed)","N"]
[33,"11:47650138_AT_A",11,47737501,"rs11039355","2019-01-14",30367059,"Teumer A","2018-10-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30367059","Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.","Free thyroxine concentration","49,269 European ancestry individuals","up to 22,383 European ancestry individuals","11p11.2","FNBP4","AGBL2 - FNBP4","ENSG00000165923","ENSG00000109920",null,560,568,"rs11039355-T","rs11039355",0,11039355,"regulatory_region_variant",1,0.34,{"v":8e-11,"d":"8.00E-11"},10.096910013008,null,0.039,"[0.027-0.051] unit decrease","Affymetrix, Illumina [8048941] (imputed)","N"]
[42,"rs3764261",16,56988044,"rs173539","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,9269,7718,"rs173539-C","rs173539",0,173539,"intergenic_variant",1,0.681,{"v":8e-11,"d":"8.00E-11"},10.096910013008,"(EA)",0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,"(Women)",0.041,"[0.029-0.053] nmol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[35,"rs11600380",11,116617240,"rs11216126","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","High density lipoprotein cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","11q23.3","Intergenic","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,88272,1646,"rs11216126-?","rs11216126",0,11216126,"intergenic_variant",1,null,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,{"$nulls":3},"Affymetrix [at least 805769] (imputed)","N"]
[42,"rs3764261",16,56987015,"rs12446515","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Total cholesterol levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8240,8747,"rs12446515-T","rs12446515",0,12446515,"regulatory_region_variant",1,0.166,{"v":9e-11,"d":"9.00E-11"},10.0457574905606,null,5.2555,"[3.67-6.84] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[3,"rs11206510",1,55496039,"rs11206510","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","LDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p32.3","PCSK9","BSND - PCSK9","ENSG00000162399","ENSG00000169174",null,18582,9182,"rs11206510-T","rs11206510",0,11206510,"intergenic_variant",1,0.77,{"v":1E-10,"d":"1.00E-10"},10,null,0.03,"[0.02-0.04] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-07-04",29769521,"Ramirez J","2018-05-16","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29769521","Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.","Resting heart rate","67,062 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.397939,{"v":1E-10,"d":"1.00E-10"},10,null,0.422407,"[0.29-0.55] unit increase","Affymetrix [~ 7800000] (imputed)","N"]
[12,"rs36205397",4,3473139,"rs6831256","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","4p16.3","LRPAP1","DOK7",null,null,"ENSG00000175920",null,null,"rs6831256-G","rs6831256",0,6831256,"intron_variant",0,0.42,{"v":1E-10,"d":"1.00E-10"},10,null,0.025,"[NR] unit increase","NR [NR] (imputed)","N"]
[17,"rs59136961",6,34763982,"rs9469890","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469890-T","rs9469890",0,9469890,"intron_variant",0,0.142,{"v":1E-10,"d":"1.00E-10"},10,null,0.054,"[0.038-0.07] unit increase","Affymetrix [7947838] (imputed)","N"]
[21,"rs2976940",8,8308044,"rs2921071","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","White blood cell count (basophil)","171,846 European ancestry individuals","NA","8p23.1","intergenic","AC103957.1 - AC103957.2","ENSG00000253505","ENSG00000254153",null,25894,6375,"rs2921071-C","rs2921071",0,2921071,"intergenic_variant",1,0.4723,{"v":1E-10,"d":"1.00E-10"},10,null,0.02283891,"[0.016-0.03] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs4360309",8,126523523,"rs4360309","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Basophil percentage of white cells","171,996 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-T","rs4360309",0,4360309,"intron_variant",0,0.4888,{"v":1E-10,"d":"1.00E-10"},10,null,0.02297412,"[0.016-0.03] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs5072",11,116908283,"rs7115242","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs7115242-?","rs7115242",0,7115242,"intron_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,{"$nulls":3},"Affymetrix [NR]","N"]
[37,"rs11066320",12,112072424,"rs11065987","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-A","rs11065987",0,11065987,"intergenic_variant",1,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.735,{"v":1E-10,"d":"1.00E-10"},10,"(EA)",0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":1E-10,"d":"1.00E-10"},10,null,0.01472,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,"NR",{"v":1E-10,"d":"1.00E-10"},10,null,0.049,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Neutrophil percentage of white cells","171,542 European ancestry individuals","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.0313,{"v":1E-10,"d":"1.00E-10"},10,null,0.06643613,"[0.046-0.087] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","1p13.3","CELSR2","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.21541,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.014155,"[0.0098-0.0185] unit increase","NR [13737936] (imputed)","N"]
[12,"rs3748034",4,3446091,"rs3748034","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Hepatocyte growth factor levels","8,292 Finnish ancestry individuals","NA","4p16.3","HGFAC","HGFAC",null,null,"ENSG00000109758",null,null,"rs3748034-G","rs3748034",0,3748034,"missense_variant",0,null,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.1495,"[0.1-0.2] SD units decrease","NR [10700000] (imputed)","N"]
[13,"rs4860948",4,69349018,"rs1117816","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","4q13.2","TMPRSS11E","TMPRSS11E, TMPRSS11E",null,null,"ENSG00000274058, ENSG00000087128",null,null,"rs1117816-A","rs1117816",0,1117816,"intron_variant",0,0.78,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.0212,"[0.015-0.028] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[17,"rs59136961",6,34827085,"rs9469913","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469913-T","rs9469913",0,9469913,"missense_variant",0,0.1823,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(women)",0.0428,"[0.03-0.056] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[21,"rs2126259",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.096,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.051,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[25,"rs4876611",8,116663898,"rs2737252","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q23.3","NR","TRPS1",null,null,"ENSG00000104447",null,null,"rs2737252-G","rs2737252",0,2737252,"intron_variant",0,0.734,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Granulocyte count","169,822 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-T","rs2954031",0,2954031,"intron_variant",0,0.4452,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.02300901,"[0.016-0.03] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs115478735",9,136154867,"rs495828","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Hemoglobin levels","up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.","16,389 European and African American individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4075,58434,"rs495828-T","rs495828",0,495828,"regulatory_region_variant",1,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(Asian)",0.1033,"[0.072-0.135] grams/deciliter decrease","Affymetrix, Illumina [2500000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2012-03-27",22359512,"Demirkan A","2012-02-16","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22359512","Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.","Phospholipid levels (plasma)","4,034 European ancestry individuals","NA","11q23.3","APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-?","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(proportions)",1,"[NR] % increase","Illumina [NR] (imputed)","N"]
[35,"rs508487",11,117075566,"rs508487","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","11q23.3","PCSK7","PCSK7",null,null,"ENSG00000160613",null,null,"rs508487-T","rs508487",0,508487,"3_prime_UTR_variant",0,0.04,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(TRIG)",0.235,"[0.16-0.31] mmol/l increase","Illumina [NR] (imputed)","N"]
[36,"rs7973253",12,109883254,"rs3742020","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","12q24.11","NR","MYO1H, AC007570.1",null,null,"ENSG00000174527, ENSG00000255655",null,null,"rs3742020-C","rs3742020",0,3742020,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.01627,"[0.011-0.021] unit increase","Affymetrix [10847151] (imputed)","N"]
[38,"rs2244608",12,121416650,"rs1169288","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls","NA","12q24.31","HNF1A","HNF1A-AS1, HNF1A",null,null,"ENSG00000241388, ENSG00000135100",null,null,"rs1169288-C","rs1169288",0,1169288,"missense_variant",0,0.323,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.04,"[1.02-1.06]","Affymetrix, Illumina [247470]","N"]
[41,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.33,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(East Asian)",0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.684,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56990716,"rs247617","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,11941,5046,"rs247617-C","rs247617",0,247617,"regulatory_region_variant",1,0.683,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19379549,"rs58542926","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","19p13.11","TM6SF2","AC138430.1, TM6SF2",null,null,"ENSG00000267629, ENSG00000213996",null,null,"rs58542926-T","rs58542926",0,58542926,"missense_variant",0,0.079,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,1.09,"[1.06-1.12]","Affymetrix, Illumina [247470]","N"]
[50,"rs149553138",19,45672478,"rs149553138","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","19q13.32","NR","TRAPPC6A, MARK4",null,null,"ENSG00000007255, ENSG00000007047",null,null,"rs149553138-A","rs149553138",0,149553138,"intron_variant",0,0.0366873,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.2052668,"[0.14-0.27] mg/dl decrease","Illumina [24111857] (imputed)","N"]
[57,"rs5754102",22,21963786,"rs5754344","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754344-A","rs5754344",0,5754344,"intron_variant",0,0.78,{"v":2e-10,"d":"2.00E-10"},9.69897000433601,null,0.045,"[0.031-0.059] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-G","rs11591147",0,11591147,"missense_variant",0,0.984,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,1.25,"[1.16-1.34]","Affymetrix [9149595] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Triglycerides-Blood Pressure (TG-BP)","22,161 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-A","rs780093",0,780093,"intron_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.18,"[0.12-0.24] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[21,"rs17155393",8,9942907,"rs12545826","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs12545826-G","rs12545826",0,12545826,"intron_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.010955,"[0.0075-0.0144] unit decrease","Affymetrix [18485882] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.2,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,3.038,"[2.1-3.98] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[33,"11:47650138_AT_A",11,47640429,"rs1064608","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Cognitive performance","257,841 European ancestry individuals","NA","11p11.2","Intergenic","MTCH2",null,null,"ENSG00000109919",null,null,"rs1064608-C","rs1064608",0,1064608,"missense_variant",0,0.3488,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.0188,"[0.013-0.025] unit decrease","Affymetrix, Illumina [10100000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-05-11",27182965,"Pickrell JK","2016-05-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27182965","Detection and interpretation of shared genetic influences on 42 human traits.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,1.052,"[1.036-1.069]","Illumina [13757430] (imputed)","N"]
[38,"rs2244608",12,121414915,"rs2255531","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Platelet count","166,066 European ancestry individuals","NA","12q24.31","HNF1A-AS1","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs2255531-A","rs2255531",0,2255531,"intron_variant",0,0.3495,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.02417885,"[0.017-0.032] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[48,"rs142158911",19,11193949,"rs10412048","2019-04-02",30166351,"Galvan-Femenia I","2018-08-30","J Med Genet","www.ncbi.nlm.nih.gov/pubmed/30166351","Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.","Disorders of lipid metabolism","4,988 Spanish ancestry individuals","NA","19p13.2","SMARCA4, LDLR","SMARCA4 - LDLR","ENSG00000127616","ENSG00000130164",null,3847,6089,"rs10412048-?","rs10412048",0,10412048,"intergenic_variant",1,null,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,"(Disorders of lipid metabolism)",0.50094855,"[0.34-0.66] unit decrease","Illumina [9499600] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,null,{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,3.34,"[2.03-4.65] mg/dL decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[57,"rs5754102",22,21984379,"rs3747093","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Mean corpuscular hemoglobin","108,054 Japanese ancestry individuals","NA","22q11.21","YDJC","YDJC - CCDC116","ENSG00000161179","ENSG00000161180",null,26,2626,"rs3747093-?","rs3747093",0,3747093,"regulatory_region_variant",1,"NR",{"v":3E-10,"d":"3.00E-10"},9.52287874528033,null,0.0281,"[0.019-0.037] unit decrease novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","Metabolic traits","4,763 Northern Finnish founder individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-A","rs1260326",0,1260326,"missense_variant",0,0.35,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(TG)",0.09,"[0.06-0.12] mmol/l increase","Illumina [329091]","N"]
[21,"rs615632",8,9805695,"rs56243511","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","8p23.1","ENSG00000238496","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,42819,102300,"rs56243511-T","rs56243511",1,1126092,"intergenic_variant",1,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.010905,"[0.0075-0.0143] unit increase","Affymetrix [18485882] (imputed)","N"]
[22,"rs6601599",8,11393764,"rs2248699","2019-03-18",27089180,"Day FR","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089180","Physical and neurobehavioral determinants of reproductive onset and success.","Age at first sexual intercourse","59,357 British ancestry males, 66,310 British ancestry females","NA","8p23.1","BLK","BLK",null,null,"ENSG00000136573",null,null,"rs2248699-G","rs2248699",0,2248699,"intron_variant",0,0.501713,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.0241414,"[0.017-0.032] unit increase","Affymetrix [641018] (imputed)","N"]
[33,"11:47650138_AT_A",11,47915299,"rs34467936","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Neurociticism","380,506 European ancestry individuals","NA","11p11.2","NR","NUP160 - AC023232.1","ENSG00000030066","ENSG00000254780",null,45192,11576,"rs34467936-A","rs34467936",0,34467936,"intergenic_variant",1,0.35405,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,6.24,"z score increase","NR [10847151] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-?","rs653178",0,653178,"intron_variant",0,"NR",{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.0507,"[0.035-0.067] unit decrease","Illumina [at least 560000] (imputed)","N"]
[42,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,0.953,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,"(EA)",0.065,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs56121005",19,11414706,"rs56121005","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","HDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","19p13.2","TSPAN16","TSPAN16, AC011472.2",null,null,"ENSG00000130167, ENSG00000267174",null,null,"rs56121005-T","rs56121005",0,56121005,"intron_variant",0,0.0129,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.1052,"[0.072-0.138] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index","up to 309,889 European ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.847998234602839,{"v":4e-10,"d":"4.00E-10"},9.39794000867203,null,0.025690204,"unit increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2017-07-18",28240269,"Suhre K","2017-02-27","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28240269","Connecting genetic risk to disease end points through the human blood plasma proteome.","Blood protein levels","997 European ancestry individuals","338 Arab, South Asian and Filipino ancestry individuals","1p13.3","PSRC1, CELSR2","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.2183735,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA, Repulsive guidance molecule A)",0.3237,"[0.22-0.42] unit decrease","Affymetrix [509946]","N"]
[26,"rs2954021",8,126491733,"rs2954031","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Sum basophil neutrophil counts","170,143 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-T","rs2954031",0,2954031,"intron_variant",0,0.4453,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.02247202,"[0.015-0.03] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[26,"rs4360309",8,126523523,"rs4360309","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-C","rs4360309",0,4360309,"intron_variant",0,0.485,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA)",0.031,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3213545",12,121443116,"rs1169314","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.31","NR","C12orf43",null,null,"ENSG00000157895",null,null,"rs1169314-A","rs1169314",0,1169314,"intron_variant",0,0.692,{"v":5e-10,"d":"5.00E-10"},9.30102999566398,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[53,"rs2378390",20,34143278,"rs3790136","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q11.22","NR","ERGIC3",null,null,"ENSG00000125991",null,null,"rs3790136-A","rs3790136",0,3790136,"intron_variant",0,"NR",{"v":5e-10,"d":"5.00E-10"},9.30102999566398,null,0.035,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109817838,"rs660240","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2",null,null,"ENSG00000143126",null,null,"rs660240-T","rs660240",0,660240,"3_prime_UTR_variant",0,0.321,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(AA)",0.171,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2011-04-11",21378988,"Coronary Artery Disease (C4D) Genetics Consortium","2011-03-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21378988","A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.","Coronary heart disease","8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls","18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-T","rs646776",0,646776,"regulatory_region_variant",1,"NR",{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,1.14,"[1.09-1.19]","Illumina [574919]","N"]
[20,"rs35348663",7,72977898,"rs12539316","2011-10-11",21909109,"Kim YJ","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909109","Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.","Gamma glutamyl transpeptidase","12,545 Korean ancestry individuals","Up to 30,395 East Asian ancestry individuals","7q11.23","TBL2","BCL7B - TBL2","ENSG00000106635","ENSG00000106638",null,5566,3965,"rs12539316-C","rs12539316",0,12539316,"intergenic_variant",1,0.1,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.0051,"[0.0035-0.0067] IU/L increase","Affymetrix [~ 2200000] (imputed)","N"]
[36,"rs7973253",12,109883117,"rs3742021","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Worry too long after an embarrassing experience","367,725 European ancestry individuals","NA","12q24.11","UNG","MYO1H",null,null,"ENSG00000174527",null,null,"rs3742021-T","rs3742021",0,3742021,"intron_variant",0,0.302806,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,6.18,"z score decrease","NR [10847151] (imputed)","N"]
[38,"rs3213545",12,121450165,"rs2264750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.31","NR","C12orf43",null,null,"ENSG00000157895",null,null,"rs2264750-C","rs2264750",0,2264750,"intron_variant",0,0.692,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,"(EA)",0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3213545",12,121454622,"rs1182933","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","12q24.31","C12orf43","C12orf43 - OASL","ENSG00000157895","ENSG00000135114",null,317,2292,"rs1182933-T","rs1182933",0,1182933,"regulatory_region_variant",1,0.2959,{"v":6E-10,"d":"6.00E-10"},9.22184874961635,null,0.02404914,"[0.016-0.032] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[2,"rs2986164",1,25715885,"rs760938","2019-01-28",30598549,"Morris JA","2018-12-31","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30598549","An atlas of genetic influences on osteoporosis in humans and mice.","Heel bone mineral density","426,824 British ancestry individuals","NA","1p36.11","RHCE","RHCE",null,null,"ENSG00000188672",null,null,"rs760938-C","rs760938",0,760938,"intron_variant",0,0.441174,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,0.0113471,"[0.0077-0.015] unit increase","NR [13737936] (imputed)","N"]
[22,"rs1692821",8,11710369,"rs1293292","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","8p23.1","CTSB","CTSB",null,null,"ENSG00000164733",null,null,"rs1293292-G","rs1293292",0,1293292,"intron_variant",0,0.71921875,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(COLEC12)",0.16800492,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[41,"rs1077835",15,58731153,"rs261342","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2, LIPC-AS1",null,null,"ENSG00000166035, ENSG00000128918, ENSG00000259293",null,null,"rs261342-G","rs261342",0,261342,"intron_variant",0,0.409,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(Hispanic)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-C","rs3764261",0,3764261,"regulatory_region_variant",1,"NR",{"v":7e-10,"d":"7.00E-10"},9.15490195998574,null,0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[55,"rs6129762",20,39811275,"rs4297946","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","PLCG1, ZHX3",null,null,"ENSG00000124181, ENSG00000174306",null,null,"rs4297946-G","rs4297946",0,4297946,"3_prime_UTR_variant",0,0.543,{"v":7e-10,"d":"7.00E-10"},9.15490195998574,"(EA)",0.029,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74934009,"rs34341","2018-07-09",29691431,"Tikkanen E","2018-04-24","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/29691431","Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.","Hand grip strength","334,825 British ancestry individuals","NA","5q13.3","ANKDD1B","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs34341-A","rs34341",0,34341,"intron_variant",0,0.4242,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,2E-3,"[0.0014-0.0026] unit increase","Affymetrix [15275733] (imputed)","N"]
[16,"rs1235162",6,29461730,"rs1233491","2016-01-30",25827949,"Kunz M","2015-05-04","Exp Dermatol","www.ncbi.nlm.nih.gov/pubmed/25827949","Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.","Cutaneous lupus erythematosus","151 European ancestry cases, 1,288 European ancestry controls","219 European ancestry cases, 262 European ancestry controls","6p22.1","MAS1L","RPS17P1 - AL662860.1","ENSG00000213900","ENSG00000229274",null,4277,3556,"rs1233491-C","rs1233491",0,1233491,"intergenic_variant",1,0.088,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,2.2,"[1.58-3.08]","Affymetrix [906600]","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","8q24.13",null,"AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-?","rs2954021",0,2954021,"intron_variant",0,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[35,"rs11820589",11,116603724,"rs12272004","2009-02-28",19185284,"Ferrucci L","2009-01-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/19185284","Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.","Carotenoid and tocopherol levels","1,191 European ancestry individuals","2,540 European ancestry individuals, 211 individuals","11q23.3","APOA5","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,74756,15162,"rs12272004-A","rs12272004",0,12272004,"TF_binding_site_variant",1,0.07,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,"(alpha-tocopherol)",0.07,"[0.049-0.095] umol/L increase","Illumina [~ 500451]","N"]
[38,"rs2244608",12,121416988,"rs2244608","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","12q24.31","HFN1A","HNF1A, HNF1A-AS1",null,null,"ENSG00000135100, ENSG00000241388",null,null,"rs2244608-G","rs2244608",0,2244608,"intron_variant",0,0.349,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,1.053,"[1.035-1.070]","Affymetrix [9149595] (imputed)","N"]
[51,"rs35106244",19,49206172,"rs516246","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-T","rs516246",0,516246,"intron_variant",0,0.47,{"v":8e-10,"d":"8.00E-10"},9.09691001300805,null,2.3,"[1.80-2.90] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[57,"rs5754102",22,21982249,"rs878825","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","22q11.21",null,"UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,3926,129,"rs878825-?","rs878825",0,878825,"intergenic_variant",1,"NR",{"v":8e-10,"d":"8.00E-10"},9.09691001300805,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[7,"rs907866",2,20369701,"rs870527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC098828.1 - RN7SL140P","ENSG00000213729","ENSG00000266059",null,13883,5406,"rs870527-T","rs870527",0,870527,"TF_binding_site_variant",1,"NR",{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2018-09-17",29844566,"Davies G","2018-05-29","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29844566","Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.","General cognitive ability","up to 300,486 European ancestry individuals","NA","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,"NR",{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,6.132,"z-score decrease","Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[36,"rs2241212",12,110002777,"rs10850379","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling hurt","372,047 European ancestry individuals","NA","12q24.11","FOXN4","MMAB",null,null,"ENSG00000139428",null,null,"rs10850379-T","rs10850379",0,10850379,"non_coding_transcript_exon_variant",0,0.425983,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,6.14,"z score increase","NR [10847151] (imputed)","N"]
[37,"rs4766578",12,111932800,"rs7137828","2016-11-18",26752265,"Bailey JN","2016-01-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26752265","Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.","Glaucoma (primary open-angle)","3,853 European ancestry cases, 33,480 European ancestry controls","2,137 European ancestry cases, 6,699 European ancestry controls, 1,037 Singaporean Chinese ancestry cases,  2,543 Singaporean Chinese ancestry controls","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-T","rs7137828",0,7137828,"intron_variant",0,0.5,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,"(European)",1.17,"NR","Affymetrix, Illumina [6425680] (imputed)","N"]
[50,"rs1065853",19,45415640,"rs445925","2016-11-01",27179730,"Allen NB","2016-01-23","Am Heart J","www.ncbi.nlm.nih.gov/pubmed/27179730","Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies.","Ideal cardiovascular health (clinical)","2,242 European ancestry individuals with clinical ideal cardiovascular health, 9,466 European ancestry individuals without clinical ideal cardiovascular health","522 European ancestry individuals","19q13.32","APOE, APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-A","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.14,{"v":9e-10,"d":"9.00E-10"},9.04575749056067,null,1.72,null,"Affymetrix [~ 25000000] (imputed)","N"]
[6,"rs199900492",1,234852760,"rs553427","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","1q42.3","LOC101927787, LINC01132","AL160408.6",null,null,"ENSG00000282097",null,null,"rs553427-?","rs553427",0,553427,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.03482,"[0.024-0.046] unit increase novel","Illumina [6108953] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2009-06-22",19503597,"Kolz M","2009-06-05","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19503597","Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.","Uric acid levels","12,328 European ancestry males, 15,813 European ancestry females","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.42,{"v":1e-09,"d":"1.00E-09"},9,null,0.05,"[0.035-0.068] mg/dl increase","Affymetrix, Illumina [2493963] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Palmitoleic acid (16:1n-7) levels","8,961 European ancestry individuals",null,"2p23.3","ZNF512, XAB1, GCKR, C2orf16","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.41,{"v":1e-09,"d":"1.00E-09"},9,null,0.02,"[0.014-0.027] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[17,"rs59136961",6,34603646,"rs2492863","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","6p21.31","C6orf106, SNRPC, UHRF1BP1","C6orf106",null,null,"ENSG00000196821",null,null,"rs2492863-A","rs2492863",0,2492863,"intron_variant",0,0.139616,{"v":1e-09,"d":"1.00E-09"},9,null,0.01709,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[20,"rs34121855",7,72977249,"rs34594435","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","7q11.23","BCL7B, TBL2","BCL7B - TBL2","ENSG00000106635","ENSG00000106638",null,4917,4614,"rs34594435-C","rs34594435",0,34594435,"intergenic_variant",1,null,{"v":1e-09,"d":"1.00E-09"},9,null,0.183,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[26,"rs2954021",8,126479315,"rs6982636","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6982636-?","rs6982636",0,6982636,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(TG.assay, whole)",0.033,"[NR] unit decrease","Illumina [335603]","N"]
[26,"rs33924196",8,126481475,"rs2980879","2012-05-10",22479202,"Dastani Z","2012-03-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22479202","Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.","Adiponectin levels","29,347 European ancestry individuals, 4,232 African American individuals, 1,776 Filipino ancestry individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980879-T","rs2980879",0,2980879,"intron_variant",0,0.69,{"v":1e-09,"d":"1.00E-09"},9,null,0.03,"[0.022-0.038] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-T","rs1883025",0,1883025,"intron_variant",0,0.26,{"v":1e-09,"d":"1.00E-09"},9,"(BMI unadjusted)",0.067,"[0.045-0.089] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[35,"rs1263056",11,116576415,"rs1263056","2019-04-12",30846698,"Dashti HS","2019-03-07","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30846698","Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.","Sleep duration","446,118 European ancestry individuals","47,180  adults, 10,554 children or adolescents","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,47447,42471,"rs1263056-A","rs1263056",0,1263056,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.768,"unit increase","Affymetrix [14661600] (imputed)","N"]
[35,"rs12721026",11,116706047,"rs12721025","2018-12-11",30281099,"Fadista J","2018-10-02","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30281099","Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis.","Infantile hypertrophic pyloric stenosis","1,395 Danish ancestry cases, 4,438 Danish ancestry controls","1,794 European ancestry cases, 633 Hispanic ancestry cases, 1,875 European ancestry controls, 633 Hispanic ancestry controls","11q23.3","NR","APOC3 - APOA1","ENSG00000110245","ENSG00000118137",null,2259,420,"rs12721025-A","rs12721025",0,12721025,"regulatory_region_variant",1,0.0606306977387014,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",1.45,"[1.33-1.57]","Illumina [6576307] (imputed)","N"]
[35,"rs5072",11,116908283,"rs7115242","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs7115242-?","rs7115242",0,7115242,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"Affymetrix [NR]","N"]
[37,"rs4766578",12,111884608,"rs3184504","2016-07-24",26192919,"Liu JZ","2015-07-20","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26192919","Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.","Inflammatory bowel disease","12,882 European ancestry cases, 21,770 European ancestry controls","25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls","12q24.12","NR","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(EA)",null,null,"Affymetrix, Illumina [~ 9000000] (imputed)","N"]
[41,"rs261341",15,58724792,"rs8034802","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","HDL cholesterol","7,813 African American individuals","4,323 African American and Afro-Caribbean individuals","15q21.3","LIPC","ALDH1A2, LIPC",null,null,"ENSG00000128918, ENSG00000166035",null,null,"rs8034802-A","rs8034802",0,8034802,"intron_variant",0,0.362,{"v":1e-09,"d":"1.00E-09"},9,null,0.104,"[0.071-0.137] unit increase","Affymetrix [~ 2740000] (imputed)","N"]
[42,"rs3764261",16,56993161,"rs12149545","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14386,2601,"rs12149545-A","rs12149545",0,12149545,"regulatory_region_variant",1,0.3035,{"v":1e-09,"d":"1.00E-09"},9,null,0.0374,"[0.025-0.05] unit decrease","Affymetrix [at least 7947838] (imputed)","N"]
[47,"rs9304381",18,47167214,"rs4939883","2013-09-24",19936222,"Chasman DI","2009-11-20","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19936222","Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.","Lipid metabolism phenotypes","Up to 17,296 European ancestry female individuals","Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls","18q21.1","LIPG","LIPG - SMUG1P1","ENSG00000101670","ENSG00000267444",null,41662,9506,"rs4939883-?","rs4939883",0,4939883,"intergenic_variant",1,"NR",{"v":1e-09,"d":"1.00E-09"},9,"(HDL.large, fasting)",0.353,"[NR] unit decrease","Illumina [335603]","N"]
[49,"rs113954889",19,19263938,"rs58190593","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Mean arterial pressure","136,482 Japanese ancestry individuals","NA","19p13.11","MEF2B, MEF2BNB-MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-?","rs58190593",0,58190593,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.02567,"[0.017-0.034] unit increase novel","Illumina [6108953] (imputed)","N"]
[50,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[55,"rs6129762",20,39672618,"rs6029526","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","TOP1",null,null,"ENSG00000198900",null,null,"rs6029526-T","rs6029526",0,6029526,"intron_variant",0,0.53,{"v":1e-09,"d":"1.00E-09"},9,"(EA)",0.028,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21916166,"rs5754100","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Autoimmune traits","approximately 459,000 European ancestry individuals","NA","22q11.21",null,"UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754100-?","rs5754100",0,5754100,"intron_variant",0,"NR",{"v":1e-09,"d":"1.00E-09"},9,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63118196,"rs10889353","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.14,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.126,"[0.085-0.167] unit decrease","Illumina [561583]","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-04-21",27899376,"Nakayama A","2016-11-29","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/27899376","GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.","Renal underexcretion gout","619 Japanese ancestry cases, 1,213 Japanese ancestry controls","696 Japanese ancestry cases, 1,268 Japanese ancestry controls","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.543,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1.35,"[1.22-1.48]","Illumina [570442]","N"]
[14,"rs56912706",5,75003678,"rs2307111","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Pulse pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.5943,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.1593,"[0.11-0.21] mmHg increase","Affymetrix [NR] (imputed)","N"]
[16,"rs1235162",6,29223493,"rs3130825","2018-10-18",30048462,"Kim SK","2018-07-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/30048462","Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.","Heel bone mineral density","394,929 European ancestry individuals","NA","6p22.1",null,"AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130825-?","rs3130825",0,3130825,"intron_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0208387,"[0.015-0.027] unit decrease","Affymetrix [20259828] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,73012042,"rs35332062","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals","132,177 European ancestry individuals","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs35332062-G","rs35332062",0,35332062,"missense_variant",0,0.8797,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02,"[0.014-0.026] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[22,"rs6601599",8,11435516,"rs10108511","2017-03-13",27527254,"Gharahkhani P","2016-08-12","Lancet Oncol","www.ncbi.nlm.nih.gov/pubmed/27527254","Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.","Barrett's esophagus  or Esophageal adenocarcinoma","6,167 European ancestry Barrett's oesophagus cases, 4,112 European ancestry esophageal adenocarcinoma cases, 17,159 European ancestry controls","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs10108511-T","rs10108511",0,10108511,"intron_variant",0,null,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,1.12,"[1.08-1.16]","Illumina [11951684] (imputed)","N"]
[26,"rs4360309",8,126523523,"rs4360309","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Basophil percentage of granulocytes","170,223 European ancestry individuals","NA","8q24.13","RP11-136O12.2","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4360309-T","rs4360309",0,4360309,"intron_variant",0,0.4887,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.02162174,"[0.015-0.029] unit decrease","Affymetrix [~ 2500000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or ischemic stroke","12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[35,"rs2000571",11,116581641,"rs2367970","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,52673,37245,"rs2367970-G","rs2367970",0,2367970,"intergenic_variant",1,0.677,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(East Asian)",0.087,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs5072",11,116707338,"rs7116797","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","11q23.3","APOA1","APOA1, APOA1-AS",null,null,"ENSG00000118137, ENSG00000235910",null,null,"rs7116797-A","rs7116797",0,7116797,"intron_variant",0,null,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.214,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[36,"rs2241212",12,109986918,"rs888194","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Positive affect","410,603 European ancestry individuals","NA","12q24.11","NR","UBE3B - MMAB","ENSG00000151148","ENSG00000139428",null,12408,4624,"rs888194-G","rs888194",0,888194,"intergenic_variant",1,0.449777406639775,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.0069014137,"[0.0046-0.0092] unit increase","NR [NR]","N"]
[36,"rs2241212",12,110000193,"rs7134594","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.11","NR","MMAB",null,null,"ENSG00000139428",null,null,"rs7134594-C","rs7134594",0,7134594,"intron_variant",0,0.466,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(EA)",0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112200150,"rs2013002","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.12","ALDH2","AC002996.1",null,null,"ENSG00000257767",null,null,"rs2013002-T","rs2013002",0,2013002,"intron_variant",0,0.44,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.896,{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(Hispanic)",0.15,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs737337",19,11347493,"rs737337","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs737337-T","rs737337",0,737337,"synonymous_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,null,0.042,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45410002,"rs769449","2017-05-11",28031287,"Sasayama D","2016-11-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28031287","Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.","Cerebrospinal fluid biomarker levels","133 Japanese ancestry individuals.","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs769449-?","rs769449",0,769449,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"Apolipoprotein E (isoform E2)",null,null,"Illumina [514227]","N"]
[50,"rs157595",19,45416478,"rs584007","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs584007-?","rs584007",0,584007,"non_coding_transcript_exon_variant",0,"NR",{"v":2e-09,"d":"2.00E-09"},8.69897000433601,"(females)",1.5096664,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[2,"rs2986164",1,25747230,"rs586178","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","1p36.11","LDLRAP1","RHCE",null,null,"ENSG00000188672",null,null,"rs586178-C","rs586178",0,586178,"missense_variant",0,0.5,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.037,"[0.025-0.049] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[2,"rs2986164",1,25775733,"rs12027135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","MACO1",null,null,"ENSG00000204178",null,null,"rs12027135-A","rs12027135",0,12027135,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-01-25",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood insulin","Up to 51,750 European ancestry individuals","Up to 33,823 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.3929,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.0189,"[0.013-0.025] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[14,"rs4704210",5,74879890,"rs5744680","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Red cell distribution width","approximately 445,000 European ancestry individuals","NA","5q13.3",null,"POLK",null,null,"ENSG00000122008",null,null,"rs5744680-?","rs5744680",0,5744680,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[19,"rs55730499",6,160997118,"rs74617384","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs74617384-T","rs74617384",0,74617384,"intron_variant",0,0.0838,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.12114009,"[0.081-0.161] mg/dl increase","Illumina [24111857] (imputed)","N"]
[20,"rs34121855",7,73026378,"rs17145750","2011-11-18",22001757,"Chambers JC","2011-10-16","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22001757","Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.","Liver enzyme levels (gamma-glutamyl transferase)","Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals","NA","7q11.23","MLXIPL","MLXIPL",null,null,"ENSG00000009950",null,null,"rs17145750-C","rs17145750",0,17145750,"intron_variant",0,0.86,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,4.5,"[2.90-6.30] % increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[21,"rs2126259",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,0.196,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(Hispanic)",0.111,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs6601599",8,11433780,"rs2409797","2017-03-13",27527254,"Gharahkhani P","2016-08-12","Lancet Oncol","www.ncbi.nlm.nih.gov/pubmed/27527254","Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.","Barrett's esophagus","6,167 European ancestry cases, 17,159 European ancestry controls","NA","8p23.1","LINC00208, BLK","AC022239.1 - LINC00208","ENSG00000269954","ENSG00000170983",null,11577,42,"rs2409797-T","rs2409797",0,2409797,"intergenic_variant",1,null,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,1.1394,"[1.1-1.18]","Illumina [11942825] (imputed)","N"]
[29,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,0.202,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(IL6ST)",0.202,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[35,"rs11820589",11,116649135,"rs11823543","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Triglycerides-Blood Pressure (TG-BP)","22,161 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs11823543-A","rs11823543",0,11823543,"3_prime_UTR_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.35,"[0.23-0.47] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,112059557,"rs11065979","2018-10-10",30054594,"MacGregor S","2018-07-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30054594","Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.","Intraocular pressure","133,492 European ancestry individuals","NA","12q24.12","ATXN2","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-?","rs11065979",0,11065979,"intergenic_variant",1,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.0776,"[0.052-0.103] unit decrease","Affymetrix, Illumina [up to 40000000] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2014-04-04",24023260,"Wu Y","2013-09-10","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/24023260","Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.","Lipid traits","1,782 Filipino ancestry mothers","1,719 Filipino ancestry offsprings","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-A","rs1800775",0,1800775,"regulatory_region_variant",1,0.4,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(HDL-C)",0.04,"[0.020-0.060] unit increase","Affymetrix [~ 3700000] (imputed)","N"]
[48,"rs737337",19,11347493,"rs737337","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","19p13.2","DOCK6, LOC55908","DOCK6",null,null,"ENSG00000130158",null,null,"rs737337-C","rs737337",0,737337,"synonymous_variant",0,0.08,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,0.64,"[0.37-0.91] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[49,"rs11882123",19,19473445,"rs2905424","2014-03-18",23974872,"Ripke S","2013-08-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23974872","Genome-wide association analysis identifies 13 new risk loci for schizophrenia.","Schizophrenia","5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls","4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios","19p13.11","CILP2, PBX4, MAU2, GMIP, LPAR2, MIR640, NCAN, GATAD2A, HAPLN4, YJEFN3, NDUFA13, SUGP1, TM6SF2, TSSK6","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,3881,23190,"rs2905424-T","rs2905424",0,2905424,"intergenic_variant",1,0.348,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,null,1.092,"[1.06-1.12]","Affymetrix, Illumina [9871789]","N"]
[50,"rs11881756",19,45220896,"rs11881756","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease","NA","19q13.32","NR","AC243964.2",null,null,"ENSG00000266903",null,null,"rs11881756-?","rs11881756",0,11881756,"intron_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(MAPK8)",0.30471954,"[NR] unit increase","Illumina [> 1000000] (imputed)","N"]
[50,"rs157595",19,45414451,"rs439401","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-?","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":3E-9,"d":"3.00E-09"},8.52287874528033,"(females)",1.5058857,null,"Affymetrix, Illumina [2928658] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63050598,"rs3850634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs3850634-T","rs3850634",0,3850634,"intron_variant",0,0.656,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(Hispanic)",0.093,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-11-05",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Hematological and biochemical traits","Up to 14,402 Japanese individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(ALB)",0.085,"[0.056-0.114] unit decrease","Illumina [561583]","N"]
[16,"rs1235162",6,29356331,"rs9257809","2012-11-30",22961001,"Su Z","2012-09-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22961001","Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.","Barrett's esophagus","Up to 1,852 European ancestry cases, 5,172 European ancestry controls","5,986 European ancestry cases, 12,825 European ancestry controls","6p22.1","OR2D12, OR2D13, MHC","OR5V1, OR5V1, OR5V1, OR5V1, OR5V1",null,null,"ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000112461, ENSG00000243441",null,null,"rs9257809-A","rs9257809",0,9257809,"intron_variant",0,0.87,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,1.21,"[1.13-1.28]","Illumina [521744]","N"]
[17,"rs59136961",6,34552797,"rs2814944","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","6p21.31","C6orf106","AL031577.1 - C6orf106","ENSG00000196114","ENSG00000196821",null,8364,2268,"rs2814944-A","rs2814944",0,2814944,"intergenic_variant",1,0.16,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.49,"[0.29-0.69] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,73042443,"rs6460047","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Serum uric acid levels","109,029 Japanese ancestry individuals","NA","7q11.23","MLXIPL, VPS37D","MLXIPL - VPS37D","ENSG00000009950","ENSG00000176428",null,3570,39712,"rs6460047-?","rs6460047",0,6460047,"intergenic_variant",1,"NR",{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.04096,"[0.027-0.055] unit decrease novel","Illumina [6108953] (imputed)","N"]
[26,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(Asian initial, BMI unadjusted)",0.049,"[0.033-0.065] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-A","rs7124681",0,7124681,"intron_variant",0,0.4117,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(EA)",0.0247,"[0.016-0.033] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47902883,"rs12364432","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Feeling lonely","376,352 European ancestry individuals","NA","11p11.2","NR","NUP160 - AC023232.1","ENSG00000030066","ENSG00000254780",null,32776,23992,"rs12364432-A","rs12364432",0,12364432,"regulatory_region_variant",1,0.339413,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,5.87,"z score decrease","NR [10847151] (imputed)","N"]
[37,"rs11066320",12,112684221,"rs7953257","2018-08-29",29912962,"Feitosa MF","2018-06-18","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29912962","Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.","Mean arterial pressure x alcohol consumption interaction (2df test)","91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers","237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers","12q24.13","HECTD4","HECTD4",null,null,"ENSG00000173064",null,null,"rs7953257-A","rs7953257",0,7953257,"intron_variant",0,0.44,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(EA)",null,null,"Affymetrix, Illumina [up to 39321347] (imputed)","N"]
[44,"rs4561509",17,45425115,"rs7206971","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","LDL cholesterol","95,454 European ancestry individuals","NA","17q21.32","OSBPL7","EFCAB13",null,null,"ENSG00000178852",null,null,"rs7206971-T","rs7206971",0,7206971,"intron_variant",0,0.35,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.87,"[0.52-1.22] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[49,"rs58542926",19,19610596,"rs3794991","2017-10-20",28869590,"Zhao W","2017-09-04","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28869590","Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.","Type 2 diabetes","6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls","7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls","19p13.11","GATAD2A, CILP2","GATAD2A",null,null,"ENSG00000167491",null,null,"rs3794991-T","rs3794991",0,3794991,"intron_variant",0,0.0775,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.077,"[0.052-0.102] unit increase","Affymetrix, Illumina [NR] (imputed)","N"]
[49,"rs58542926",19,19658472,"rs16996148","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","Triglycerides","2,758 European ancestry individuals","18,554 European ancestry individuals","19p13.11","CILP2, PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-T","rs16996148",0,16996148,"intergenic_variant",1,0.1,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,null,0.1,"[0.06-0.14] unit decrease","Affymetrix [389878]","N"]
[57,"rs5754102",22,21982054,"rs1811069","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","22q11.21","NR","UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,3731,324,"rs1811069-T","rs1811069",0,1811069,"intergenic_variant",1,0.801,{"v":4e-09,"d":"4.00E-09"},8.39794000867203,"(EA)",0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74910870,"rs984976","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs984976-A","rs984976",0,984976,"intron_variant",0,0.466,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(East Asian)",0.095,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1235162",6,29248149,"rs3130834","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","AL672167.1",null,null,"ENSG00000197171",null,null,"rs3130834-C","rs3130834",0,3130834,"intron_variant",0,0.0955,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(EA)",0.0672,"[0.045-0.09] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[20,"rs34121855",7,72999105,"rs9638182","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","TBL2 - MLXIPL","ENSG00000106638","ENSG00000009950",null,5984,8419,"rs9638182-T","rs9638182",0,9638182,"intergenic_variant",1,0.869,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(Hispanic)",0.12,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18286997,"rs6997340","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","up to 122,733 cases, up to 424,528 controls","NA","8p22","intergenic","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,28269,97814,"rs6997340-T","rs6997340",0,6997340,"intergenic_variant",1,0.3025,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.0331,"[0.022-0.044] unit increase","Affymetrix [at least 7947838] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,0.738,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(EA)",0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116639104,"rs10790162","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs10790162-A","rs10790162",0,10790162,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.25,"[0.17-0.33] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[36,"rs2241212",12,110000193,"rs7134594","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.11","NR","MMAB",null,null,"ENSG00000139428",null,null,"rs7134594-C","rs7134594",0,7134594,"intron_variant",0,"NR",{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2009-05-19",19430479,"Levy D","2009-05-10","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19430479","Genome-wide association study of blood pressure and hypertension.","Systolic blood pressure","29,136 European ancestry individuals","34,433 European ancestry individuals","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.48,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,null,0.58,"[0.38-0.78] mm Hg increase","Affymetrix, Illumina [2533153] (imputed)","N"]
[52,"rs59774409",19,50045916,"rs34459162","2018-08-10",29844224,"Loomis SJ","2018-05-29","Diabetes","www.ncbi.nlm.nih.gov/pubmed/29844224","Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results from the Atherosclerosis Risk in Communities Study.","Fructosamine levels","7,647 European ancestry individuals, 2,104 Black individuals","1,304 European ancestry individuals, 608 Black individuals","19q13.33","RCN3","RCN3",null,null,"ENSG00000142552",null,null,"rs34459162-C","rs34459162",0,34459162,"missense_variant",0,0.08,{"v":5e-09,"d":"5.00E-09"},8.30102999566398,"(EA)",0.02,"[0.014-0.026] unit decrease","Affymetrix [NR] (imputed)","N"]
[5,"rs611917",1,109819296,"rs3902354","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,924,2882,"rs3902354-C","rs3902354",0,3902354,"intergenic_variant",1,0.331,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(EA)",0.025,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs3817588",2,27743154,"rs780092","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780092-A","rs780092",0,780092,"intron_variant",0,0.67,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(BMI unadjusted)",0.058,"[0.038-0.078] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[16,"rs1235162",6,29075088,"rs3129178","2017-11-30",29059683,"Michailidou K","2017-10-23","Nature","www.ncbi.nlm.nih.gov/pubmed/29059683","Association analysis identifies 65 new breast cancer risk loci.","Breast cancer","76,192 European ancestry cases, 63,082 European ancestry controls","46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls","6p22.1","NR","OR2J1 - OR2J3","ENSG00000225441","ENSG00000232178",null,4610,748,"rs3129178-A","rs3129178",0,3129178,"intergenic_variant",1,0.0951,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(EA)",0.0669,"[0.044-0.089] unit decrease","Illumina [~ 11800000] (imputed)","N"]
[22,"rs6601599",8,11433909,"rs2898290","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Pulse pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,null,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,0.151,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[32,"rs10793624",10,46024729,"rs11239550","2017-05-11",28017375,"van Rooij FJA","2016-12-22","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/28017375","Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.","Mean corpuscular hemoglobin","up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.","16,389 individuals of European and African American ancestry.","10q11.22","2008-03-01","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239550-A","rs11239550",0,11239550,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(Asian)",0.0049,"[0.0033-0.0065] unit decrease","NR [2500000] (imputed)","N"]
[35,"rs11820589",11,116633862,"rs11820589","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","11q23.3","BUD13","BUD13",null,null,"ENSG00000137656",null,null,"rs11820589-A","rs11820589",0,11820589,"missense_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,"(TG-GLUC)",0.32,"[0.20-0.44] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-10-19",30093612,"O'Mara TA","2018-08-09","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30093612","Identification of nine new susceptibility loci for endometrial cancer.","Endometrial cancer (endometrioid histology)","8,758 European ancestry cases, 46,126 European ancestry controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.515767,{"v":6E-9,"d":"6.00E-09"},8.22184874961635,null,1.11,"[1.07-1.15]","Affymetrix, Illumina [~ 11700000] (imputed)","N"]
[57,"rs5754102",22,21974703,"rs5754387","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","22q11.21",null,"UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754387-?","rs5754387",0,5754387,"intron_variant",0,"NR",{"v":6E-9,"d":"6.00E-09"},8.22184874961635,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2013-11-29",23726366,"Coram MA","2013-05-29","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23726366","Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.","Triglycerides","7,601 African American individuals, 3,335 Hispanic individuals","7,138 African American individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.358,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Hispanic)",0.0688,"[NR] unit increase","Affymetrix [NR]","N"]
[14,"rs253412",5,74965554,"rs42302","2018-11-12",30038396,"Lee JJ","2018-07-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30038396","Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.","Educational attainment (MTAG)","1,311,438 European ancestry individuals","NA","5q13.3","Intergenic","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs42302-A","rs42302",0,42302,"intron_variant",0,0.3441,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(MTAG)",0.008,"[0.0053-0.0107] unit increase","Affymetrix, Illumina [7100000] (imputed)","N"]
[21,"rs615632",8,9892177,"rs658385","2019-03-18",27089180,"Day FR","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089180","Physical and neurobehavioral determinants of reproductive onset and success.","Age at first sexual intercourse","59,357 British ancestry males, 66,310 British ancestry females","NA","8p23.1","MSRA","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,129301,15818,"rs658385-T","rs658385",0,658385,"regulatory_region_variant",1,0.55416,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.0223478,"[0.015-0.03] unit increase","Affymetrix [641018] (imputed)","N"]
[32,"rs148063610",10,46013277,"rs970548","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","34,930 East Asian ancestry individuals, 187,167 European ancestry individuals","8,741 Chinese ancestry individuals","10q11.22","MARCH8, ALOX5","2008-03-01",null,null,"ENSG00000165406",null,null,"rs970548-A","rs970548",0,970548,"intron_variant",0,0.723,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,"(Trans-ethnic initial)",0.0258,"[0.018-0.033] unit decrease (EA Beta values)","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2018-06-29",28714469,"Langefeld CD","2017-07-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28714469","Transancestral mapping and genetic load in systemic lupus erythematosus.","Systemic lupus erythematosus","6,748 European ancestry cases, 11,516 European ancestry controls, 2,970 African American cases, 2,452 African American controls, 1,872 Hispanic cases, 2,016 Hispanic controls","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-C","rs653178",0,653178,"intron_variant",0,"NR",{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.14,"[1.08-1.20]","Illumina [at least 5000000] (imputed)","N"]
[41,"rs1077835",15,58727325,"rs261332","2017-08-30",27863252,"Astle WJ","2016-11-17","Cell","www.ncbi.nlm.nih.gov/pubmed/27863252","The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.","Hemoglobin concentration","172,925 European ancestry individuals","NA","15q21.3","RP11-355N15.1","LIPC, LIPC-AS1, ALDH1A2",null,null,"ENSG00000166035, ENSG00000259293, ENSG00000128918",null,null,"rs261332-G","rs261332",0,261332,"non_coding_transcript_exon_variant",0,0.792,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,0.02541862,"[0.017-0.034] unit increase","Affymetrix [~ 2500000] (imputed)","N"]
[49,"rs58542926",19,19407718,"rs10401969","2017-12-11",22885922,"Morris AP","2012-09-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22885922","Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.","Type 2 diabetes","6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls","12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls","19p13.11","CILP2","SUGP1",null,null,"ENSG00000105705",null,null,"rs10401969-C","rs10401969",0,10401969,"intron_variant",0,0.080536977769365,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.13,"[1.09-1.18]","Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2017-02-17",27189021,"Cook JP","2016-05-18","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27189021","Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.","Type 2 diabetes","746 African American cases, 2,825 African American controls, 743 East Asian ancestry cases, 3,992 East Asian ancestry controls, 7,111 European ancestry cases, 49,688 European ancestry controls, 1,147 Latino cases, 5,352 Latino controls","12,171 European ancestry cases, 56,862 European ancestry controls","19q13.32","TOMM40, APOE","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-C","rs6857",0,6857,"3_prime_UTR_variant",0,0.844,{"v":7e-09,"d":"7.00E-09"},8.15490195998574,null,1.12,"[1.08-1.16]","NR [at least 8497425] (imputed)","N"]
[7,"rs907866",2,20369701,"rs870527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC098828.1 - RN7SL140P","ENSG00000213729","ENSG00000266059",null,13883,5406,"rs870527-T","rs870527",0,870527,"TF_binding_site_variant",1,0.517,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(EA)",0.027,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741105,"rs780095","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Fasting plasma glucose","15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780095-G","rs780095",0,780095,"intron_variant",0,0.4267,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(Non diabetics)",0.070907116,"[0.047-0.095] mmol/L increase","Illumina [24111857] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2012-08-15",22581228,"Manning AK","2012-05-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22581228","A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.","Fasting blood glucose (BMI interaction)","Up to 58,074 European ancestry individuals","Up tp 38,422 European ancestry individuals","8p23.1","PPP1R3B","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-A","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0936,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,{"v":0.0006183,"d":"6.18E-04"},"[-0.00148-0.00272] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[32,"rs148063610",10,46013277,"rs970548","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","Cholesterol, total","94,595 European ancestry individuals","93,982 European ancestry individuals","10q11.22","MARCH8, ALOX5","2008-03-01",null,null,"ENSG00000165406",null,null,"rs970548-C","rs970548",0,970548,"intron_variant",0,0.26,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,null,0.025,"[NR] unit increase","NR [NR] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2016-10-06",26621817,"Cheng TH","2015-12-01","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26621817","Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.","Colorectal or endometrial cancer","5,725 European ancestry colorectal carcinoma cases, 2,212 European ancestry endometrial carcinoma cases, 13,396 European ancestry controls","4,330 European ancestry endometrial carcinoma cases, 26,849 European ancestry controls","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.52,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(same direction)",1.1,"[1.06-1.13]","Illumina [up to 6000000] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.49,{"v":8e-09,"d":"8.00E-09"},8.09691001300805,"(East Asian)",0.083,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs2986164",1,25768937,"rs10903129","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","MACO1",null,null,"ENSG00000204178",null,null,"rs10903129-A","rs10903129",0,10903129,"intron_variant",0,"NR",{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11250098",8,10943276,"rs2409691","2019-03-18",30643258,"Karlsson Linner R","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643258","Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.","Automobile speeding propensity","404,291 European ancestry individuals","NA","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs2409691-T","rs2409691",0,2409691,"intron_variant",0,0.4822,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,null,0.012960173,"[0.0085-0.0174] unit decrease","Affymetrix [11514463] (imputed)","N"]
[35,"rs12721026",11,117032959,"rs12281009","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","11q23.3",null,"PAFAH1B2",null,null,"ENSG00000168092",null,null,"rs12281009-?","rs12281009",0,12281009,"intron_variant",0,"NR",{"v":9e-09,"d":"9.00E-09"},8.04575749056067,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[41,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.861,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-11-16",30072576,"Emilsson V","2018-08-02","Science","www.ncbi.nlm.nih.gov/pubmed/30072576","Co-regulatory networks of human serum proteins link genetics to disease.","Blood protein levels","3,200 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-C","rs7412",0,7412,"missense_variant",0,0.93734375,{"v":9e-09,"d":"9.00E-09"},8.04575749056067,"(GNAI3)",0.28634983,"[NR] unit decrease","Illumina [> 1000000] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease or ischemic stroke","12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls","NA","1p13.3","SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-?","rs599839",0,599839,"regulatory_region_variant",1,null,{"v":1E-8,"d":"1.00E-08"},8,{"$nulls":3},"Affymetrix, Illumina [up to 2500000] (imputed)","N"]
[14,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,0.48,{"v":1E-8,"d":"1.00E-08"},8,"(East Asian)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74877803,"rs5744672","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","Cholesterol, total","19,259 British ancestry individuals from 6863 families.","NA","5q13.3","NR","POLK",null,null,"ENSG00000122008",null,null,"rs5744672-C","rs5744672",0,5744672,"non_coding_transcript_exon_variant",0,0.378799,{"v":1E-8,"d":"1.00E-08"},8,null,0.06437605,"[0.042-0.086] mg/dl increase","Illumina [24111857] (imputed)","N"]
[15,"rs6882345",5,156390297,"rs6882076","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","5q33.3","TIMD4","TIMD4 - HAVCR1","ENSG00000145850","ENSG00000113249",null,31,66127,"rs6882076-?","rs6882076",0,6882076,"regulatory_region_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.04276,"[0.028-0.057] unit increase novel","Illumina [6108953] (imputed)","N"]
[21,"rs2126259",8,9183596,"rs4841132","2017-06-21",28270201,"Nagy R","2017-03-07","Genome Med","www.ncbi.nlm.nih.gov/pubmed/28270201","Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.","HDL cholesterol","19,223 British ancestry individuals from 6863 families.","NA","8p23.1","RP-11-115 J16.1","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841132-G","rs4841132",0,4841132,"non_coding_transcript_exon_variant",0,0.0925,{"v":1E-8,"d":"1.00E-08"},8,null,0.10894712,"[0.072-0.146] mg/dl increase","Illumina [24111857] (imputed)","N"]
[29,"rs3824477",9,107589567,"rs7024300","2016-12-01",26879886,"Wakil SM","2016-02-16","Clin Genet","www.ncbi.nlm.nih.gov/pubmed/26879886","A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.","Low high density lipoprotein cholesterol levels","1,747 Saudi Arab ancestry cases, 2,335 Saudi Arab ancestry controls","517 Saudi Arab ancestry cases, 896 Saudi Arab ancestry controls","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs7024300-T","rs7024300",0,7024300,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,1.4492754,"[1.11-1.92]","Affymetrix [~ 8000000] (imputed)","N"]
[29,"rs2740488",9,107661742,"rs2740488","2016-10-10",26691988,"Fritsche LG","2015-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26691988","A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.","Advanced age-related macular degeneration","16,144 European ancestry cases, 17,832 European ancestry controls","473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-?","rs2740488",0,2740488,"intron_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,"(EA)",1.1111112,null,"Illumina [12023830] (imputed)","N"]
[33,"11:47650138_AT_A",11,47606483,"rs11605348","2018-09-12",29942086,"Savage JE","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942086","Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.","Intelligence","269,867 European ancestry individuals","NA","11p11.2","NR","NDUFS3 - FAM180B","ENSG00000213619","ENSG00000196666",null,369,1762,"rs11605348-A","rs11605348",0,11605348,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,5.735,"z-score decrease","Affymetrix, Illumina [9295118] (imputed)","N"]
[33,"11:47650138_AT_A",11,47915299,"rs34467936","2019-05-02",30867560,"Hill WD","2019-03-13","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30867560","Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.","General factor of neuroticism","270,059 British ancestry individuals","NA","11p11.2","ENSG00000254780","NUP160 - AC023232.1","ENSG00000030066","ENSG00000254780",null,45192,11576,"rs34467936-A","rs34467936",0,34467936,"intergenic_variant",1,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.0098816,"[0.0065-0.0133] unit decrease","Affymetrix [18485882] (imputed)","N"]
[36,"rs2241212",12,109898732,"rs1558804","2019-03-18",30643256,"Baselmans BML","2019-01-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30643256","Multivariate genome-wide analyses of the well-being spectrum.","Life satisfaction","80,852 European ancestry individuals","NA","12q24.11","NR","KCTD10",null,null,"ENSG00000110906",null,null,"rs1558804-G","rs1558804",0,1558804,"intron_variant",0,0.451036247292579,{"v":1E-8,"d":"1.00E-08"},8,null,0.007299709,"[0.0048-0.0098] unit increase","NR [NR]","N"]
[36,"rs7973253",12,110027795,"rs11067376","2019-01-22",29500382,"Nagel M","2018-03-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29500382","Item-level analyses reveal genetic heterogeneity in neuroticism.","Irritable mood","366,726 European ancestry individuals","NA","12q24.11","NR","MVK",null,null,"ENSG00000110921",null,null,"rs11067376-A","rs11067376",0,11067376,"non_coding_transcript_exon_variant",0,0.359496,{"v":1E-8,"d":"1.00E-08"},8,null,5.67,"z score decrease","NR [~ 10847151] (imputed)","N"]
[37,"rs4766578",12,112007756,"rs653178","2016-10-14",26390057,"Kato N","2015-09-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26390057","Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.","Diastolic blood pressure","31,516 East Asian ancestry individuals,  35,352 European ancestry individuals, 33,126 South Asian ancestry individuals","87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs653178-T","rs653178",0,653178,"intron_variant",0,0.5018,{"v":1E-8,"d":"1.00E-08"},8,"(EA)",0.5511,"[0.36-0.74] mmHg decrease","Affymetrix, Illumina, Perlegen [~ 2100000] (imputed)","N"]
[40,"rs6602911",13,114542858,"rs9604573","2017-10-24",28898252,"Wheeler E","2017-09-12","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/28898252","Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.","Glycated hemoglobin levels","88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals","33,238 European ancestry individuals,  2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals","13q34","GAS6","GAS6-AS1, GAS6",null,null,"ENSG00000233695, ENSG00000183087",null,null,"rs9604573-T","rs9604573",0,9604573,"non_coding_transcript_exon_variant",0,0.2738,{"v":1E-8,"d":"1.00E-08"},8,"(European)",0.0101,"[0.0066-0.0136] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[42,"rs3764261",16,56993886,"rs821840","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15111,1876,"rs821840-A","rs821840",0,821840,"regulatory_region_variant",1,0.733,{"v":1E-8,"d":"1.00E-08"},8,"(Hispanic)",0.1,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs4783961",16,56994894,"rs4783961","2019-05-02",30911093,"Bandesh K","2019-03-25","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30911093","Genome-wide association study of blood lipids in Indians confirms universality of established variants.","High density lipoprotein cholesterol levels","1,036 Indian ancestry individuals","4,235 Indian ancestry individuals, 188,577 European ancestry individuals, 7,898 East Asian, South Asian and African ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16118,941,"rs4783961-G","rs4783961",0,4783961,"regulatory_region_variant",1,0.44,{"v":1E-8,"d":"1.00E-08"},8,"(Indian)",1.29,"[0.84-1.74] unit decrease","Illumina [551825]","N"]
[48,"rs142158911",19,11188899,"rs112374545","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs112374545-C","rs112374545",0,112374545,"intron_variant",0,0.833,{"v":1E-8,"d":"1.00E-08"},8,"(AA)",0.194,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.848,{"v":1E-8,"d":"1.00E-08"},8,"(EA)",0.026,"[0.017-0.035] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[50,"rs157595",19,45414451,"rs439401","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","HDL Cholesterol - Triglycerides (HDLC-TG)","22,161 European ancestry individuals","NA","19q13.32","LOC100129500","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-C","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":1E-8,"d":"1.00E-08"},8,null,0.24,"[0.16-0.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[51,"rs35106244",19,49213284,"rs584768","2019-02-26",30566020,"Fukaya E","2018-12-01","Circulation","www.ncbi.nlm.nih.gov/pubmed/30566020","Clinical and Genetic Determinants of Varicose Veins.","Varicose veins","9,577 British ancestry cases, 327,959 British ancestry controls","NA","19q13.33","NR","FUT2 - MAMSTR","ENSG00000176920","ENSG00000176909",null,4077,2715,"rs584768-A","rs584768",0,584768,"intergenic_variant",1,0.53,{"v":1E-8,"d":"1.00E-08"},8,null,0.084,"[0.055-0.113] unit increase","Affymetrix [10972371] (imputed)","N"]
[2,"rs2986164",1,25758134,"rs11249249","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Heel bone mineral density","approximately 446,000 European ancestry individuals","NA","1p36.11",null,"MACO1",null,null,"ENSG00000204178",null,null,"rs11249249-?","rs11249249",0,11249249,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[7,"rs907866",2,20367973,"rs11899121","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC098828.1 - RN7SL140P","ENSG00000213729","ENSG00000266059",null,12155,7134,"rs11899121-G","rs11899121",0,11899121,"regulatory_region_variant",1,0.509,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs62122520",2,21278773,"rs934198","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,11828,68016,"rs934198-G","rs934198",0,934198,"intergenic_variant",1,0.716,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.092,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2011-10-20",21943158,"Middelberg RP","2011-09-24","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/21943158","Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.","Cardiovascular disease risk factors","11,683 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.4,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(TRIG)",0.082,"[0.053-0.111] mmol/l increase","Illumina [NR] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2018-02-20",29385134,"Kawaguchi T","2018-01-31","PLoS One","www.ncbi.nlm.nih.gov/pubmed/29385134","Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.","Nonalcoholic fatty liver disease","902 Japanese ancestry cases, 7,672 Japanese ancestry controls","NA","2p23.3","C2orf16, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.57,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.35,"[1.21-1.49]","Illumina [93606]","N"]
[11,"rs3770586",2,169829772,"rs2389606","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","2q31.1","ABCB11","ABCB11, ABCB11",null,null,"ENSG00000073734, ENSG00000276582",null,null,"rs2389606-T","rs2389606",0,2389606,"intron_variant",0,0.5793,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0149,"[0.0098-0.02] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.482,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(East Asian)",0.091,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs4704210",5,74759183,"rs4704221","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","COL4A3BP",null,null,"ENSG00000113163",null,null,"rs4704221-?","rs4704221",0,4704221,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"Affymetrix [NR]","N"]
[16,"rs1235162",6,28776117,"rs4324798","2009-11-09",19836008,"Landi MT","2009-10-15","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/19836008","A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.","Lung adenocarcinoma","5,739 European ancestry cases, 5,848 European ancestry controls","7,561 European ancestry cases, 13,818 European ancestry controls","6p22.1","TRNAA-UGC","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,24336,29529,"rs4324798-A","rs4324798",0,4324798,"intergenic_variant",1,0.09,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.16,"[1.09-1.24]","Illumina [515922]","N"]
[19,"rs3777411",6,160506462,"rs2297363","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","6q25.3","LPA","IGF2R",null,null,"ENSG00000197081",null,null,"rs2297363-A","rs2297363",0,2297363,"intron_variant",0,0.26,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(BMI unadjusted)",0.022,"[0.014-0.03] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[25,"rs4876611",8,116648565,"rs2737229","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","Cholesterol, total","100,184 European ancestry individuals","NA","8q23.3","TRPS1","TRPS1",null,null,"ENSG00000104447",null,null,"rs2737229-C","rs2737229",0,2737229,"intron_variant",0,0.3,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.11,"[0.7-1.52] mg/dL decrease","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[26,"rs2980884",8,126474356,"rs2980884","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","White blood cell count (basophil)","62,076 Japanese ancestry individuals","NA","8q24.13","TRIB1, LINC00861","TRIB1 - AC091114.1","ENSG00000173334","ENSG00000253111",null,23709,4825,"rs2980884-?","rs2980884",0,2980884,"intergenic_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.03688,"[0.024-0.05] unit increase novel","Illumina [6108953] (imputed)","N"]
[30,"rs9411377",9,136149098,"rs116552240","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Non-albumin protein levels","98,538 Japanese ancestry individuals","NA","9q34.2","ABO","ABO",null,null,"ENSG00000175164",null,null,"rs116552240-?","rs116552240",1,8176645,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.02581,"[0.017-0.035] unit increase novel","Illumina [6108953] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-A","rs7124681",0,7124681,"intron_variant",0,0.4018,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0227,"[0.015-0.031] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[36,"rs2241212",12,109986918,"rs888194","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","12q24.11",null,"UBE3B - MMAB","ENSG00000151148","ENSG00000139428",null,12408,4624,"rs888194-?","rs888194",0,888194,"intergenic_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[36,"rs2241212",12,110002777,"rs10850379","2018-10-31",29942085,"Nagel M","2018-06-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29942085","Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.","Worry","348,219 European ancestry individuals","NA","12q24.11","NR","MMAB",null,null,"ENSG00000139428",null,null,"rs10850379-T","rs10850379",0,10850379,"non_coding_transcript_exon_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.01356,"[0.0089-0.0183] unit increase","Affymetrix [10847151] (imputed)","N"]
[37,"rs4766578",12,112059557,"rs11065979","2017-07-13",28537254,"Tsoi LC","2017-05-24","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28537254","Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.","Psoriasis","Up to 11,988 European ancestry cases, up to 275,335 European ancestry controls","7,044 European ancestry cases, 11,434 European ancestry controls","12q24.12","BRAP, MAPKAPK5","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,0.45,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,1.08,null,"Illumina, Perlegen [9113515] (imputed)","N"]
[38,"rs3213545",12,121443116,"rs1169314","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","12q24.31","HNF1A","C12orf43",null,null,"ENSG00000157895",null,null,"rs1169314-G","rs1169314",0,1169314,"intron_variant",0,0.3,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.037,"[0.023-0.051] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[41,"rs75127556",15,58692681,"rs56903760","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Low density lipoprotein cholesterol levels","72,866 Japanese ancestry individuals","NA","15q21.3","AQP9, LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs56903760-?","rs56903760",0,56903760,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.0334,"[0.022-0.045] unit increase novel","Illumina [6108953] (imputed)","N"]
[42,"rs193695",16,56985139,"rs9989419","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6363,10696,"rs9989419-A","rs9989419",0,9989419,"regulatory_region_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.022,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs3761077",19,19336608,"rs2238675","2016-11-10",26780889,"Below JE","2016-01-19","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/26780889","Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.","LDL cholesterol","4,383 Mexican ancestry individuals","7,876 Latin American/Hispanic individuals,  European ancestry individuals (Global Lipids Genetics Consortium et al, 2013)","19p13.11","NCAN","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.887,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(Hispanic)",0.125,"[0.082-0.168] unit increase","Affymetrix [at least 370268] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2013-02-28",23207651,"Davies G","2012-12-04","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/23207651","A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.","Cognitive decline","3,280 European ancestry individuals","1,367 European ancestry individuals","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.2,"[0.12-0.28] unit decrease","Illumina [549692]","N"]
[51,"rs35106244",19,49206172,"rs516246","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-C","rs516246",0,516246,"intron_variant",0,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206417,"rs492602","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs492602-A","rs492602",0,492602,"synonymous_variant",0,0.518,{"v":2E-8,"d":"2.00E-08"},7.69897000433601,"(EA)",0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[55,"rs6129762",20,39950805,"rs2866611","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","20q12","NR","ZHX3 - ADI1P1","ENSG00000174306","ENSG00000235102",null,4493,8958,"rs2866611-?","rs2866611",0,2866611,"regulatory_region_variant",1,"NR",{"v":2E-8,"d":"2.00E-08"},7.69897000433601,{"$nulls":3},"Affymetrix [NR]","N"]
[8,"rs4564803",2,21206183,"rs6754295","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,121650,16002,"rs6754295-C","rs6754295",0,6754295,"intergenic_variant",1,0.25,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.08,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Gondoic acid (20:1n-9) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,2E-3,"[-0.00192-0.00592] unit decrease","Affymetrix, Illumina [2200000] (imputed)","N"]
[9,"rs1260326",2,27748624,"rs1260333","2016-10-07",26582766,"Lu X","2015-11-18","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/26582766","Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.","Cholesterol, total","8,344 Han Chinese ancestry individuals","14,739 Han Chinese ancestry individuals","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,2073,11629,"rs1260333-A","rs1260333",0,1260333,"intergenic_variant",1,0.52,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.773,"[1.15-2.4] unit increase","Affymetrix, Illumina [2573667] (imputed)","N"]
[14,"rs4704210",5,74879890,"rs5744680","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","POLK",null,null,"ENSG00000122008",null,null,"rs5744680-?","rs5744680",0,5744680,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"Affymetrix [NR]","N"]
[17,"rs114863007",6,34592090,"rs6907508","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","LDL cholesterol","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","6p21.31","C6orf106","C6orf106",null,null,"ENSG00000196821",null,null,"rs6907508-A","rs6907508",0,6907508,"intron_variant",0,0.888,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.0244,"[0.016-0.033] mg dl−1 increase","Affymetrix [up to 31400000] (imputed)","N"]
[18,"rs6934962",6,116399372,"rs6932852","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q22.1","NR","FRK - NT5DC1","ENSG00000111816","ENSG00000178425",null,17451,22640,"rs6932852-C","rs6932852",0,6932852,"intergenic_variant",1,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[20,"rs34121855",7,73016862,"rs13240994","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","MLXIPL",null,null,"ENSG00000009950",null,null,"rs13240994-T","rs13240994",0,13240994,"intron_variant",0,0.865,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Hispanic)",0.112,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs62568184",9,107657070,"rs3905000","2018-07-02",29615537,"Kulminski AM","2018-03-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29615537","Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.","High density lipoprotein cholesterol levels","up to 33,431 European ancestry individuals","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-A","rs3905000",0,3905000,"intron_variant",0,0.1354,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.6761924,"[1.08-2.27] unit decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[32,"rs148063610",10,46007533,"rs11239544","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","Cholesterol, total","up to 62,166 European ancestry individuals","NA","10q11.22","2008-03-01","2008-03-01",null,null,"ENSG00000165406",null,null,"rs11239544-T","rs11239544",0,11239544,"intron_variant",0,0.27,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.037,"[0.023-0.051] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[36,"rs2241212",12,109895168,"rs2338104","2008-09-16",18193043,"Willer CJ","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193043","Newly identified loci that influence lipid concentrations and risk of coronary artery disease.","HDL cholesterol","8,656 European ancestry individuals","11,437 European ancestry individuals","12q24.11","MVK, MMAB","KCTD10",null,null,"ENSG00000110906",null,null,"rs2338104-G","rs2338104",0,2338104,"non_coding_transcript_exon_variant",0,0.45,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.48,"[NR] mg/dl increase","Affymetrix, Illumina [~ 2261000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2013-06-06",23417110,"Tin A","2013-02-16","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23417110","Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.","Beta-2 microglubulin plasma levels","6,728 European ancestry individuals",null,"12q24.12","SH2B3, ATXN2","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,0.49,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.02,"[0.012-0.028] unit decrease","Affymetrix [2500000] (imputed)","N"]
[37,"rs11066320",12,112072424,"rs11065987","2016-09-12",26394269,"Cordell HJ","2015-09-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26394269","International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.","Primary biliary cholangitis","2,764 European ancestry cases, 10,475 European ancestry controls","3,716 European ancestry cases,  4,261 European ancestry controls","12q24.12","ATXN2, SH2B3, TRAFD1, ALDH2","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,34364,7526,"rs11065987-G","rs11065987",0,11065987,"intergenic_variant",1,0.37,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,1.1904762,"NR","Illumina [1143634] (imputed)","N"]
[42,"rs3764261",16,56989590,"rs247616","2011-11-16",22003152,"Grallert H","2011-10-14","Eur Heart J","www.ncbi.nlm.nih.gov/pubmed/22003152","Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.","Lipoprotein-associated phospholipase A2 activity and mass","12,126 European ancestry individuals, 1,538 individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-T","rs247616",0,247616,"intergenic_variant",1,0.32,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,"(Mass concentrations)",0.023,"[0.015-0.031] unit increase","Affymetrix, Illumina [2661766] (imputed)","N"]
[49,"rs58542926",19,19658472,"rs16996148","2008-06-16",18193044,"Kathiresan S","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193044","Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.","LDL cholesterol","2,758 European ancestry individuals","18,544 European ancestry individuals","19p13.11","CILP2, PBX4","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,1004,14044,"rs16996148-T","rs16996148",0,16996148,"intergenic_variant",1,0.1,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.1,"[0.06-0.14] unit decrease","Affymetrix [389878]","N"]
[49,"19:19756073_AGCC_A",19,19786099,"rs58434384","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","White blood cell count","approximately 444,000 European ancestry individuals","NA","19p13.11",null,"ZNF101",null,null,"ENSG00000181896",null,null,"rs58434384-?","rs58434384",0,58434384,"intron_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2017-08-10",28641921,"Li J","2017-05-15","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/28641921","Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.","Cerebrospinal fluid t-tau levels","113 European ancestry Alzheimer's disease cases, 207 European ancestry individuals with late mild cognitive impairment, 239 European ancestry individuals with early mild cognitive impairment, 85 European ancestry individuals with significant memory concern, 199 European ancestry controls.","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-?","rs2075650",0,2075650,"intron_variant",0,null,{"v":3e-08,"d":"3.00E-08"},7.52287874528033,{"$nulls":3},"Illumina [563980]","N"]
[53,"rs2378390",20,34152782,"rs2277862","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q11.22","NR","FER1L4",null,null,"ENSG00000088340",null,null,"rs2277862-C","rs2277862",0,2277862,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-08,"d":"3.00E-08"},7.52287874528033,null,0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21123352,"rs6711016","2012-04-03",22399527,"Kristiansson K","2012-03-07","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/22399527","Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.","Metabolic syndrome","2,637 European ancestry cases, 7,927 European ancestry controls","NA","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,61931,75721,"rs6711016-C","rs6711016",0,6711016,"regulatory_region_variant",1,0.71,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(TG)",0.08,"[NR] mmol/l increase","Illumina [1257079] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.742,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(Hispanic)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs56912706",5,75003678,"rs2307111","2019-03-07",30578418,"Giri A","2018-12-21","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30578418","Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.","Diastolic blood pressure","365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals","299,024 European ancestry individuals, 17,277 individuals","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.5369,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.1404,"[0.09-0.191] mmHg decrease","Affymetrix [NR] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2011-04-11",21386085,"Kraja AT","2011-03-08","Diabetes","www.ncbi.nlm.nih.gov/pubmed/21386085","A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.","Metabolic syndrome (bivariate traits)","22,161 European ancestry individuals","NA","8p23.1","LOC100129150","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(HDLC-WC)",0.24,"[0.16-0.32] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[34,"rs72997616",11,75474195,"rs72997616","2018-11-26",30275531,"Klarin D","2018-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30275531","Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.","Total cholesterol levels","215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals","Up to 319,677 individuals","11q13.5","CTD-2530H12.1","AP001922.1, DGAT2",null,null,"ENSG00000247867, ENSG00000062282",null,null,"rs72997616-A","rs72997616",0,72997616,"intron_variant",0,0.1232,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.0243,"[0.016-0.033] mg dl−1 decrease","Affymetrix [up to 31400000] (imputed)","N"]
[35,"rs11820589",11,116652207,"rs12286037","2010-05-26",20442857,"Suchindran S","2010-04-29","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20442857","Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.","Lipoprotein-associated phospholipase A2 activity and mass","6,668 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs12286037-T","rs12286037",0,12286037,"intron_variant",0,0.07,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(activity)",6.4,"[NR] nmol/ml/min increase","Affymetrix [360811]","N"]
[37,"rs2384049",12,113137572,"rs2891403","2019-02-06",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Body mass index","approximately 458,000 European ancestry individuals","NA","12q24.13",null,"RPH3A",null,null,"ENSG00000089169",null,null,"rs2891403-?","rs2891403",0,2891403,"intron_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[42,"rs1968905",16,57017662,"rs1801706","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","High density lipoprotein cholesterol levels","70,657 Japanese ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs1801706-?","rs1801706",0,1801706,"3_prime_UTR_variant",0,"NR",{"v":4e-08,"d":"4.00E-08"},7.39794000867203,"(conditional on round 6)",0.04579008,"[0.029-0.062] unit increase novel","Illumina [6108953] (imputed)","N"]
[50,"rs75627662",19,45413576,"rs75627662","2019-01-16",30361487,"Yan Q","2018-10-25","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30361487","Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.","Cerebral amyloid deposition (PET imaging)","983 European ancestry individuals","NR","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-T","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,0.23,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,0.08,"unit increase","Illumina [at least 7000000] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Myocardial infarction","27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","19q13.32","APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-A","rs56131196",0,56131196,"intergenic_variant",1,0.16,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,1.09,"[1.06-1.12]","Affymetrix, Illumina [8600000] (imputed)","N"]
[57,"rs5754102",22,21979289,"rs4821124","2018-04-25",23143594,"Tsoi LC","2012-12-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23143594","Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.","Psoriasis","10,588 European ancestry cases, 22,806 European ancestry controls","NA","22q11.21","UBE2L3","UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,966,3089,"rs4821124-C","rs4821124",0,4821124,"intergenic_variant",1,0.189,{"v":4e-08,"d":"4.00E-08"},7.39794000867203,null,1.13,null,"Illumina [111236] (imputed)","N"]
[9,"rs1260326",2,27741072,"rs780096","2018-03-05",29304378,"Medina-Gomez C","2018-01-04","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29304378","Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.","Total body bone mineral density","56,284 European ancestry individuals, up to 1,333 African American individuals, up to 9,328 admixed individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780096-C","rs780096",0,780096,"intron_variant",0,0.4406,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.0311,"unit decrease","Affymetrix, Illumina [~ 23700000] (imputed)","N"]
[14,"rs253412",5,75015242,"rs2112347","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","5q13.3","C5orf37","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.6128,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(women)",0.0233,"[0.015-0.032] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[19,"rs12208357",6,160551486,"rs112201728","2018-05-30",29545352,"Li Y","2018-03-15","J Am Soc Nephrol","www.ncbi.nlm.nih.gov/pubmed/29545352","Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.","Urinary metabolite concentrations in chronic kidney disease","1,143 European ancestry cases","NA","6q25.3","SLC22A1","SLC22A1",null,null,"ENSG00000175003",null,null,"rs112201728-T","rs112201728",0,112201728,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,"(Butyrylcarnitine, Isobutyrylcarnitine)",0.389716,"[0.25-0.53] unit decrease","Illumina [up to 9281895] (imputed)","N"]
[35,"rs473172",11,116732512,"rs2075292","2008-06-16",18193046,"Kooner JS","2008-01-13","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/18193046","Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.","Triglycerides","1,005 European ancestry male individuals, 1,006 Indian Asian ancestry male individuals","6,827 European ancestry individuals, 2,528 Mexican ancestry individuals, 1,181 Indian Asian ancestry female individuals","11q23.3","LOC645044, APOA1, KIAA0999","SIK3",null,null,"ENSG00000160584",null,null,"rs2075292-G","rs2075292",0,2075292,"intron_variant",0,0.24,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,8.7,"[5.76-11.64] % increase","Perlegen [up to 216774]","N"]
[50,"rs76670936",19,45196581,"rs76670936","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.31","NR","AC243964.2",null,null,"ENSG00000266903",null,null,"rs76670936-?","rs76670936",0,76670936,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs148933445",19,45302504,"rs148933445","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs148933445-?","rs148933445",0,148933445,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs6509173",19,45333834,"rs4803760","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,9156,15598,"rs4803760-?","rs4803760",0,4803760,"intergenic_variant",1,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs2927482",19,45341948,"rs10407439","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,17270,7484,"rs10407439-?","rs10407439",0,10407439,"intergenic_variant",1,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs61642202",19,45358026,"rs143459034","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs143459034-?","rs143459034",0,143459034,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs117310449",19,45393516,"rs117310449","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","AC011481.2",null,null,"ENSG00000267114",null,null,"rs117310449-?","rs117310449",0,117310449,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2009-01-14",19060910,"Sabatti C","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060910","Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.","LDL cholesterol","4,763 Northern Finnish founder individuals","NA","19q13.32","APO cluster","TOMM40",{"$nulls":5},"rs157580-G","rs157580",0,157580,"intron_variant",0,0.29,{"v":5e-08,"d":"5.00E-08"},7.30102999566398,null,0.11,"[0.07-0.15] mmol/l decrease","Illumina [329091]","N"]
[50,"rs2238681",19,45403858,"rs760136","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs760136-?","rs760136",0,760136,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs5112",19,45431658,"rs8106813","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","APOC1P1",null,null,"ENSG00000214855",null,null,"rs8106813-?","rs8106813",0,8106813,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs145887105",19,45516881,"rs34874378","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","RELB",null,null,"ENSG00000104856",null,null,"rs34874378-?","rs34874378",0,34874378,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[50,"rs7245887",19,45524119,"rs114248186","2018-07-20",29777097,"Marioni RE","2018-05-18","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/29777097","GWAS on family history of Alzheimer's disease.","Alzheimer's disease or family history of Alzheimer's disease","up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls","NA","19q13.32","NR","RELB",null,null,"ENSG00000104856",null,null,"rs114248186-?","rs114248186",0,114248186,"intron_variant",0,"NR",{"v":5e-08,"d":"5.00E-08"},7.30102999566398,{"$nulls":3},"Affymetrix [7795605] (imputed)","N"]
[4,"1:62980399_CACA_C",1,62996838,"rs1168013","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","1p31.3","DOCK7, ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168013-G","rs1168013",0,1168013,"intron_variant",0,0.65,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.04,"[0.03-0.05] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[11,"rs3770586",2,169830155,"rs2287623","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2q31.1","NR","ABCB11, ABCB11",null,null,"ENSG00000073734, ENSG00000276582",null,null,"rs2287623-G","rs2287623",0,2287623,"intron_variant",0,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs6601599",8,11433909,"rs2898290","2017-09-22",28739976,"Wain LV","2017-07-24","Hypertension","www.ncbi.nlm.nih.gov/pubmed/28739976","Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.","Systolic blood pressure","150,134 European ancestry individuals","87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals","8p23.1","BLK, GATA4","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-C","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,0.525,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(EA, initial)",0.39,"[0.25-0.53] unit decrease","Affymetrix, Illumina, Perlegen [7994604] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-01-18",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Stroke","40,585 European ancestry cases, 406,111 European ancestry controls","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[35,"rs11820589",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.941,{"v":6e-08,"d":"6.00E-08"},7.22184874961635,"(AA)",0.258,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112486818,"rs17696736","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.13","NR","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,"NR",{"v":6e-08,"d":"6.00E-08"},7.22184874961635,null,0.019,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2015-07-07",25288136,"Cornelis MC","2014-10-07","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/25288136","Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.","Coffee consumption (cups per day)","91,462 European ancestry individuals","30,062 European ancestry individuals, 7,964 African American individuals","2p23.3","GCKR, FNDC4","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.41,{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.04,"[0.020-0.060] unit decrease","Affymetrix, Illumina [2373958] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2012-09-25",22829776,"Coviello AD","2012-07-19","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22829776","A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.","Sex hormone-binding globulin levels","21,791 European ancestry individuals","8,175 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.4,{"v":7e-08,"d":"7.00E-08"},7.15490195998574,"(Men)",0.026,"[0.016-0.036] nmol/L decrease","Affymetrix, Illumina [2543887] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.034,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs2244608",12,121380544,"rs2649999","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Hair color","approximately 452,000 European ancestry individuals","NA","12q24.31",null,"HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs2649999-?","rs2649999",0,2649999,"intron_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,"NR",{"v":7e-08,"d":"7.00E-08"},7.15490195998574,null,0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[2,"rs2986164",1,25768937,"rs10903129","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","MACO1",null,null,"ENSG00000204178",null,null,"rs10903129-A","rs10903129",0,10903129,"intron_variant",0,0.459,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(EA)",0.025,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs59136961",6,34773727,"rs2395607","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs2395607-T","rs2395607",0,2395607,"intron_variant",0,0.1724,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(EA)",0.03,"[0.019-0.041] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[37,"rs4766578",12,111833788,"rs10774624","2019-01-25",30423114,"Laufer VA","2018-11-13","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30423114","Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.","Rheumatoid arthritis","916 African American cases, 1,392 African American controls,","4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls","12q24.12","SH2B3, PTPN11","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-A","rs10774624",0,10774624,"intron_variant",0,"NR",{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,0.17559,"[-0.06944-0.42062] unit decrease","Illumina [8380626] (imputed)","N"]
[38,"rs2244608",12,121416988,"rs2244608","2013-03-15",23263486,"Kottgen A","2012-12-23","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23263486","Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.","Urate levels","49,825 European ancestry males, 60,522 European ancestry females","Up to 32,813 European ancestry individuals","12q24.31","HNF1A","HNF1A, HNF1A-AS1",null,null,"ENSG00000135100, ENSG00000241388",null,null,"rs2244608-A","rs2244608",0,2244608,"intron_variant",0,0.68,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,"(women)",0.036,"[0.023-0.049] mg/dl increase","Affymetrix, Illumina, Perlegen [2450547] (imputed)","N"]
[57,"rs5754102",22,21956653,"rs2283790","2018-04-25",23749187,"Cortes A","2013-07-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23749187","Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.","Ankylosing spondylitis","9,069 European ancestry cases, 1,550 East Asian ancestry cases, 13,578 European ancestry controls, 1,567 East Asian ancestry controls","NA","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs2283790-G","rs2283790",0,2283790,"intron_variant",0,0.196,{"v":8e-08,"d":"8.00E-08"},7.09691001300805,null,1.12,null,"Illumina [128935]","N"]
[9,"rs1260326",2,27741237,"rs780094","2009-02-13",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","Triglycerides","2,659 European ancestry type 2 diabetes cases and controls","5,217 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.35,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,0.5,"(% variance) increase","Affymetrix [389878]","N"]
[29,"rs4149307",9,107591272,"rs2853579","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2853579-G","rs2853579",0,2853579,"synonymous_variant",0,"NR",{"v":9e-08,"d":"9.00E-08"},7.04575749056067,null,0.032,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs113954889",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Mean arterial pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.3413,{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(Japanese)",0.3118,"[0.2-0.43] unit increase","Illumina [6200000] (imputed)","N"]
[49,"rs58542926",19,19494483,"rs150268548","2017-09-21",28736931,"Rotroff DM","2017-07-24","Clin Pharmacol Ther","www.ncbi.nlm.nih.gov/pubmed/28736931","Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.","LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes","781 European ancestry individuals, 138 African American ancestry individuals, 345 unknown ancestry individuals",null,"19p13.11","PBX4, MAU2","MAU2 - GATAD2A","ENSG00000129933","ENSG00000167491",null,24919,2152,"rs150268548-?","rs150268548",0,150268548,"intergenic_variant",1,"NR",{"v":9e-08,"d":"9.00E-08"},7.04575749056067,"(EA)",0.028,"unit decrease","Affymetrix, Illumina [8129838] (imputed)","N"]
[8,"rs4564803",2,21205502,"rs4564803","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,120969,16683,"rs4564803-G","rs4564803",0,4564803,"intergenic_variant",1,0.742,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.082,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1235162",6,29090011,"rs116442863","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung cancer in ever smokers","23,223 European ancestry cases,  16,964 European ancestry controls","NA","6p22.1","OR2J3, OR2J2","OR2J3 - AL645937.2","ENSG00000232178","ENSG00000227206",null,7464,1976,"rs116442863-A","rs116442863",1,3129112,"intergenic_variant",1,0.082472477,{"v":1e-07,"d":"1.00E-07"},7,null,1.1634282,"[1.100081716-1.230422468]","Illumina [10439017] (imputed)","N"]
[21,"rs2976940",8,8307643,"rs2921073","2017-10-24",28892059,"Chang D","2017-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28892059","A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.","Parkinson's disease","20,184 European ancestry cases, 397,324 European ancestry controls","5,851 European ancestry cases, 5,866 European ancestry controls","8p23.1","NR","AC103957.1 - AC103957.2","ENSG00000253505","ENSG00000254153",null,25493,6776,"rs2921073-C","rs2921073",0,2921073,"intergenic_variant",1,"NR",{"v":1e-07,"d":"1.00E-07"},7,null,1.0615711,"[1.04-1.08]","Illumina [11933700] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.168,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.105,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for body mass index","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":1e-07,"d":"1.00E-07"},7,"(EA, women)",0.0502,"[0.032-0.069] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":1e-07,"d":"1.00E-07"},7,"(men)",0.0254,"[0.016-0.035] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[35,"rs11604424",11,116651115,"rs11604424","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs11604424-C","rs11604424",0,11604424,"intron_variant",0,0.355,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.081,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs12721026",11,116782974,"rs11216185","2012-03-03",22306654,"Feenstra B","2012-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/22306654","Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.","Infantile hypertrophic pyloric stenosis","1,001 European ancestry cases, 2,401 European ancestry controls","796 European ancestry cases, 876 European ancestry controls","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs11216185-G","rs11216185",0,11216185,"intron_variant",0,0.05,{"v":1e-07,"d":"1.00E-07"},7,null,1.57,"[1.33-1.86]","Illumina [523420]","N"]
[37,"rs11066320",12,112610714,"rs11066188","2019-02-28",27736895,"Franceschini N","2016-10-13","PLoS One","www.ncbi.nlm.nih.gov/pubmed/27736895","Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans.","Diastolic blood pressure","19,706 Hispanic individuals, 18,744 African American individuals","NA","12q24.13","HECTD4","HECTD4",null,null,"ENSG00000173064",null,null,"rs11066188-A","rs11066188",0,11066188,"intron_variant",0,0.26,{"v":1e-07,"d":"1.00E-07"},7,"(Hispanic)",0.7,"[0.45-0.95] unit increase","Illumina [up to 196725]","N"]
[41,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.569,{"v":1e-07,"d":"1.00E-07"},7,"(AA)",0.114,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs113954889",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Diastolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.3413,{"v":1e-07,"d":"1.00E-07"},7,"(Japanese)",0.2807,"[0.18-0.38] unit increase","Illumina [6200000] (imputed)","N"]
[49,"19:19756073_AGCC_A",19,19793545,"rs56408111","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Mean corpuscular hemoglobin","approximately 443,000 European ancestry individuals","NA","19p13.11",null,"ZNF101",null,null,"ENSG00000181896",null,null,"rs56408111-?","rs56408111",0,56408111,"3_prime_UTR_variant",0,"NR",{"v":1e-07,"d":"1.00E-07"},7,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.849,{"v":1e-07,"d":"1.00E-07"},7,"(EA, women)",0.031,"[0.02-0.042] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.883,{"v":1e-07,"d":"1.00E-07"},7,"(East Asian)",0.146,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs4564803",2,21204025,"rs6544366","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","Triglycerides","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","2p24.1","APOB","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,119492,18160,"rs6544366-T","rs6544366",0,6544366,"intergenic_variant",1,0.22,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.04,"[0.03-0.05] unit decrease","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[8,"rs4564803",2,21221035,"rs4665710","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,136502,1150,"rs4665710-A","rs4665710",0,4665710,"intergenic_variant",1,0.247,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.082,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-08-13",27898682,"Lotta LA","2016-11-29","PLoS Med","www.ncbi.nlm.nih.gov/pubmed/27898682","Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.","Branched-chain amino acid levels (Leucine)","16,596 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.049,"[0.023-0.075] unit increase","Affymetrix, Illumina [10500000] (imputed)","N"]
[9,"2:28122343_GT_G",2,28143017,"rs10173848","2019-02-08",30595370,"Kichaev G","2018-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30595370","Leveraging Polygenic Functional Enrichment to Improve GWAS Power.","Lung function (FEV1/FVC)","approximately 370,000 European ancestry individuals","NA","2p23.2",null,"BABAM2, MRPL33",null,null,"ENSG00000158019, ENSG00000243147",null,null,"rs10173848-?","rs10173848",0,10173848,"intron_variant",0,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,{"$nulls":3},"NR [~ 8900000] (imputed)","N"]
[14,"rs56912706",5,75038718,"rs258494","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","5q13.3","POC5, SV2C","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,25412,9677,"rs258494-C","rs258494",0,258494,"intergenic_variant",1,null,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.212,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[16,"rs1235162",6,28983274,"rs3131082","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tuberculosis","4,426 European ancestry cases, 84,290 European ancestry controls","NA","6p22.1","NR","ZNF311 - OR2AD1P","ENSG00000197935","ENSG00000233650",null,10181,11183,"rs3131082-?","rs3131082",0,3131082,"regulatory_region_variant",1,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.1949,"[0.12-0.27] unit decrease","Illumina [at least 560000] (imputed)","N"]
[21,"rs2126259",8,9183358,"rs9987289","2016-09-19",26433129,"Tin A","2015-10-03","Diabet Med","www.ncbi.nlm.nih.gov/pubmed/26433129","GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.","Plasma lactate levels","6,901 European ancestry individuals","1,671 African American individuals","8p23.1","PPP1R3B, LOC157273","AC022784.1",null,null,"ENSG00000248538",null,null,"rs9987289-A","rs9987289",0,9987289,"non_coding_transcript_exon_variant",0,0.09,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.05,"[NR] unit increase","Affymetrix [~ 38000000] (imputed)","N"]
[25,"rs4876612",8,116813905,"rs800586","2012-06-19",22491018,"Wang J","2012-04-10","Pharmacogenomics J","www.ncbi.nlm.nih.gov/pubmed/22491018","Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.","Response to tocilizumab in rheumatoid arthritis","1,157 European and other ancestry rheumatoid arthritis cases","526 European and other ancestry rheumatoid arthritis cases","8q23.3","intergenic","TRPS1",null,null,"ENSG00000104447",null,null,"rs800586-?","rs800586",0,800586,"intron_variant",0,0.38,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(CTJC , EA, RF-)",9.78,"[NR] unit decrease","Illumina [534053]","N"]
[30,"rs115478735",9,136154168,"rs579459","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease","33,398 cases, 75,726 controls","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-C","rs579459",0,579459,"regulatory_region_variant",1,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,1.1,"[1.06-1.14]","Illumina [575000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47669175,"rs59360790","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Body fat percentage","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","11p11.2","NR","MTCH2 - AGBL2","ENSG00000109919","ENSG00000165923",null,5000,11968,"rs59360790-?","rs59360790",0,59360790,"intergenic_variant",1,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(female)",0.18308,"[0.11-0.25] unit increase","Affymetrix [7794483] (imputed)","N"]
[35,"rs11820589",11,116662407,"rs3135506","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs3135506-G","rs3135506",0,3135506,"missense_variant",0,0.897,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(Hispanic)",0.127,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111833788,"rs10774624","2019-01-25",30423114,"Laufer VA","2018-11-13","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30423114","Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.","Rheumatoid arthritis","916 African American cases, 1,392 African American controls,","4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls","12q24.12","SH2B3, PTPN11","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-A","rs10774624",0,10774624,"intron_variant",0,0.51,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",0.08647,"[0.054-0.119] unit decrease","Illumina [8380626] (imputed)","N"]
[42,"rs117427818",16,57015091,"rs5880","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs5880-G","rs5880",0,5880,"missense_variant",0,0.984,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(AA)",0.482,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"19:19510831_AT_A",19,19657500,"rs10402308","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (trunk fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","19p13.11","CILP2, FLJ44968, GATAD2A, KIAA0892, NDUFA13, SF4, TM6SF2, TSSK6","CILP2 - PBX4","ENSG00000160161","ENSG00000105717",null,32,15016,"rs10402308-A","rs10402308",0,10402308,"intergenic_variant",1,0.189997,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(females)",0.01621,"NR unit decrease (replication)","Affymetrix [25472837] (imputed)","N"]
[50,"rs149214960",19,45329214,"rs10402271","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,4536,20218,"rs10402271-T","rs10402271",0,10402271,"regulatory_region_variant",1,"NR",{"v":2e-07,"d":"2.00E-07"},6.69897000433601,null,0.019,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.905,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(East Asian)",0.152,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2018-07-24",26426971,"Winkler TW","2015-10-01","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/26426971","The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.","Body mass index x age interaction","up to 112,279 European ancestry individuals aged <50, up to 197,610 European ancestry individuals aged >50","NA","19q13.32","APOC1, ZNF229, IGSF23, BCL3, PVRL2, CLPTM1, GEMIN7, EXOC3L2, KLC3, ZNF180, PVR, CBLC, TOMM40, RELB, PPP1R37, MARK4, ERCC1, CEACAM20, MIR4531, BCAM, APOE, CLASRP, BLOC1S3, CKM, CEACAM22P","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.82,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,{"$nulls":3},"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(East Asian)",0.143,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21979096,"rs11089637","2014-08-05",24390342,"Okada Y","2013-12-25","Nature","www.ncbi.nlm.nih.gov/pubmed/24390342","Genetics of rheumatoid arthritis contributes to biology and drug discovery.","Rheumatoid arthritis","up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls","up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls","22q11.21","YDJC, UBE2L3","UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,773,3282,"rs11089637-C","rs11089637",0,11089637,"intergenic_variant",1,0.16,{"v":2e-07,"d":"2.00E-07"},6.69897000433601,"(EA)",1.1,"[1.06-1.15]","Affymetrix, Illumina [up to 9739303] (imputed)","N"]
[8,"rs4564803",2,21226560,"rs2678379","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs2678379-A","rs2678379",0,2678379,"intron_variant",0,0.247,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Hispanic)",0.081,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs59136961",6,34773727,"rs2395607","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs2395607-?","rs2395607",0,2395607,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[20,"7:73042302_GCTTT_G",7,72864869,"rs714052","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Triglycerides","8,993 Japanese ancestry individuals","NA","7q11.23","MIXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-G","rs714052",0,714052,"intron_variant",0,0.11,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.123,"[0.076-0.170] unit decrease","Illumina [561583]","N"]
[30,"rs115478735",9,136155000,"rs635634","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-C","rs635634",0,635634,"regulatory_region_variant",1,0.793,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(East Asian)",0.101,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs2072560",11,116611733,"rs9326246","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease","33,398 cases, 75,726 controls","NA","11q23.3","ZNF259, APOA1, APO5A","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,82765,7153,"rs9326246-C","rs9326246",0,9326246,"intergenic_variant",1,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,1.15,"[1.09-1.21]","Illumina [575000] (imputed)","N"]
[36,"rs2241212",12,110000193,"rs7134594","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.11","NR","MMAB",null,null,"ENSG00000139428",null,null,"rs7134594-C","rs7134594",0,7134594,"intron_variant",0,0.466,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",0.024,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112486818,"rs17696736","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","12q24.13","NR","NAA25",null,null,"ENSG00000111300",null,null,"rs17696736-A","rs17696736",0,17696736,"intron_variant",0,0.553,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(EA)",0.019,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[38,"rs3213545",12,121454622,"rs1182933","2018-04-06",29422604,"Klein AP","2018-02-08","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29422604","Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.","Pancreatic cancer","9,040 European ancestry cases, 12,496 European ancestry controls","up to 2,737 cases, up to 4,752 controls","12q24.31","HNF1A","C12orf43 - OASL","ENSG00000157895","ENSG00000135114",null,317,2292,"rs1182933-T","rs1182933",0,1182933,"regulatory_region_variant",1,0.3,{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,1.11,"[1.07 - 1.15]","Illumina [11381182] (imputed)","N"]
[47,"rs1320700",18,47107152,"rs12970066","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","LIPG",null,null,"ENSG00000101670",null,null,"rs12970066-C","rs12970066",0,12970066,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs62117206",19,45242173,"rs1531517","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,12858,8789,"rs1531517-G","rs1531517",0,1531517,"regulatory_region_variant",1,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2010-11-23",20932310,"Han MR","2010-10-08","BMC Neurol","www.ncbi.nlm.nih.gov/pubmed/20932310","Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.","Cerebrospinal fluid AB1-42 levels","172 European ancestry Alzheimer's disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-G","rs2075650",0,2075650,"intron_variant",0,"NR",{"v":3e-07,"d":"3.00E-07"},6.52287874528033,"(Controls)",null,null,"Illumina [498205]","N"]
[2,"rs2986164",1,25747230,"rs586178","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p36.11","NR","RHCE",null,null,"ENSG00000188672",null,null,"rs586178-G","rs586178",0,586178,"missense_variant",0,0.555,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(EA)",0.026,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs253412",5,75015242,"rs2112347","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","5q13.3","C5orf37","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.6128,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(men)",0.0243,"[0.015-0.034] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[22,"rs11250098",8,11078781,"rs4512344","2017-07-14",28472463,"Mullin BH","2017-05-04","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28472463","Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation.","Bone ultrasound measurement (broadband ultrasound attenuation)","1,268 whole genome sequenced European ancestry women, 8,880 European ancestry women, 6,479 European ancestry men","NA","8p23.1","XKR6, MTMR9","AF131215.7 - LINC00529","ENSG00000270076","ENSG00000236827",null,17601,26354,"rs4512344-A","rs4512344",0,4512344,"regulatory_region_variant",1,0.49,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.06,"[0.04-0.08] unit increase","Illumina [11973598] (imputed)","N"]
[30,"rs115478735",9,136154168,"rs579459","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3505,59004,"rs579459-T","rs579459",0,579459,"regulatory_region_variant",1,0.79,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,"(East Asian)",0.099,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs12721028",11,116741553,"rs11216168","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs11216168-A","rs11216168",0,11216168,"intron_variant",0,0.1471,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.0185,"[0.011-0.026] unit decrease","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Cholesterol, total","21,848 European ancestry individuals, 714 Orcadian individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-G","rs1532085",0,1532085,"intron_variant",0,0.59,{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.05,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[44,"rs4561509",17,45674687,"rs8072100","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","17q21.32","ITGB3, C17orf57, TBKBP1, KPNB1, NPEPPS","NPEPPS",null,null,"ENSG00000141279",null,null,"rs8072100-A","rs8072100",0,8072100,"intron_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,5.059,"[NR] Z score increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[50,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.049,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206674,"rs601338","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Number of common colds","43,826 European ancestry cases, 15,720 European ancestry controls","NA","19q13.33","NR","FUT2",null,null,"ENSG00000176920",null,null,"rs601338-?","rs601338",0,601338,"stop_gained",0,"NR",{"v":4e-07,"d":"4.00E-07"},6.39794000867203,null,0.0198,"[0.012-0.027] unit increase","Illumina [at least 560000] (imputed)","N"]
[8,"rs4564803",2,21231524,"rs676210","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs676210-G","rs676210",0,676210,"missense_variant",0,0.757,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[16,"rs1235162",6,29480224,"rs385816","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Pneumonia","40,600 European ancestry cases, 90,039 European ancestry controls","NA","6p22.1","NR","AL662860.1 - LINC01015","ENSG00000229274","ENSG00000224582",null,1891,16303,"rs385816-?","rs385816",0,385816,"intergenic_variant",1,"NR",{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.0742,"[0.045-0.103] unit increase","Illumina [at least 560000] (imputed)","N"]
[22,"rs11250098",8,10802146,"rs12546366","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (arm fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","8p23.1","XKR6","XKR6",null,null,"ENSG00000171044",null,null,"rs12546366-T","rs12546366",0,12546366,"intron_variant",0,0.4529,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(males)",0.01806,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[29,"rs62568184",9,107647655,"rs3890182","2010-10-17",20864672,"Waterworth DM","2010-09-23","Arterioscler Thromb Vasc Biol","www.ncbi.nlm.nih.gov/pubmed/20864672","Genetic variants influencing circulating lipid levels and risk of coronary artery disease.","HDL cholesterol","up to 17,723 European ancestry individuals","up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs3890182-G","rs3890182",0,3890182,"intron_variant",0,0.88,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.02,"[0.01-0.03] unit increase","Affymetrix, Illumina, Perlegen [2155369] (imputed)","N"]
[41,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.294,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(Hispanic)",0.069,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs11882123",19,19446936,"rs769267","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","MAU2",null,null,"ENSG00000129933",null,null,"rs769267-?","rs769267",0,769267,"synonymous_variant",0,"NR",{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.0434,"[0.027-0.06] unit increase","Illumina [at least 560000] (imputed)","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.906,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,null,0.028,"[0.017-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[50,"rs111606839",19,45448465,"rs5167","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-T","rs5167",0,5167,"missense_variant",0,0.643,{"v":5e-07,"d":"5.00E-07"},6.30102999566398,"(EA)",0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2017-07-13",28298293,"Hu Y","2017-03-15","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28298293","Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.","Gondoic acid (20:1n-9) levels","3,521 Chinese ancestry individuals, 12,020 European ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.412,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",2E-3,"[0.002-0.002] unit decrease","Affymetrix, Illumina [2200000] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.596,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(Hispanic)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs2740488",9,107664301,"rs1883025","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1883025-C","rs1883025",0,1883025,"intron_variant",0,0.738,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",0.027,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs11066320",12,112591686,"rs17630235","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","12q24.13","TRAFD1","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-G","rs17630235",0,17630235,"intergenic_variant",1,0.584,{"v":6e-07,"d":"6.00E-07"},6.22184874961635,"(EA)",0.016,"[0.0095-0.0217] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[55,"rs6129762",20,39950805,"rs2866611","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","20q12","NR","ZHX3 - ADI1P1","ENSG00000174306","ENSG00000235102",null,4493,8958,"rs2866611-?","rs2866611",0,2866611,"regulatory_region_variant",1,"NR",{"v":6e-07,"d":"6.00E-07"},6.22184874961635,{"$nulls":3},"Affymetrix [NR]","N"]
[4,"1:62980399_CACA_C",1,63078222,"rs10889348","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889348-A","rs10889348",0,10889348,"intron_variant",0,0.66,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63128081,"rs1168103","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","1p31.3","DOCK7, ATG4C, USP1","DOCK7",null,null,"ENSG00000116641",null,null,"rs1168103-T","rs1168103",0,1168103,"intron_variant",0,"NR",{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,4.968,"[NR] Z score decrease","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[22,"rs10903342",8,11522784,"rs4295623","2016-12-08",26835600,"Hu Y","2016-02-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26835600","GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.","Morning vs. evening chronotype","38,937 European ancestry morning chronotype individuals, 50,346 European ancestry evening chronotype individuals","NA","8p23.1","NR","LINC00208 - GATA4","ENSG00000170983","ENSG00000136574",null,83933,11684,"rs4295623-?","rs4295623",0,4295623,"intergenic_variant",1,"NR",{"v":7e-07,"d":"7.00E-07"},6.15490195998574,{"$nulls":3},"Illumina [7427422] (imputed)","N"]
[30,"rs115478735",9,136153875,"rs651007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q34.2","NR","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,3212,59297,"rs651007-C","rs651007",0,651007,"intergenic_variant",1,0.791,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(East Asian)",0.097,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,0.564,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(EA)",0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs737337",19,11347493,"rs737337","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs737337-T","rs737337",0,737337,"synonymous_variant",0,0.804,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,"(Hispanic)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.035,{"v":7e-07,"d":"7.00E-07"},6.15490195998574,null,1.09,"[1.05-1.13]","Affymetrix, Illumina [247470]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,0.055,"[0.033-0.077] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[26,"rs2954021",8,126486409,"rs17321515","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs17321515-A","rs17321515",0,17321515,"intron_variant",0,0.47,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(LDL)",0.07,"mmol/L increase","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-A","rs7124681",0,7124681,"intron_variant",0,0.4117,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,"(EA, women)",0.024,"[0.014-0.034] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[50,"rs75627662",19,45413576,"rs75627662","2019-01-31",29274321,"Chung J","2017-12-20","Alzheimers Dement","www.ncbi.nlm.nih.gov/pubmed/29274321","Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.","Hippocampal volume in Alzheimer's disease dementia","190 European ancestry Alzheimer's disease dementia cases","NA","19q13.32","BCAM, PVRL2, TOMM40, APOE, APOC1, APOC1P1, APOC4, APOC4-APOC2, APOC2, CLPTM1, RELB","AC011481.3",null,null,"ENSG00000267282",null,null,"rs75627662-T","rs75627662",0,75627662,"non_coding_transcript_exon_variant",0,0.27,{"v":8e-07,"d":"8.00E-07"},6.09691001300805,null,0.51,"[0.31-0.71] unit decrease","Illumina [8437147] (imputed)","N"]
[14,"rs4704210",5,74625487,"rs7703051","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","AC008897.2",null,null,"ENSG00000247372",null,null,"rs7703051-C","rs7703051",0,7703051,"intron_variant",0,0.618,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(Hispanic)",0.076,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[53,"rs2378390",20,34143278,"rs3790136","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q11.22","NR","ERGIC3",null,null,"ENSG00000125991",null,null,"rs3790136-A","rs3790136",0,3790136,"intron_variant",0,0.836,{"v":9e-07,"d":"9.00E-07"},6.04575749056067,"(EA)",0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[59,"rs372038686",23,109939205,"rs5943057","2011-04-11",21378988,"Coronary Artery Disease (C4D) Genetics Consortium","2011-03-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21378988","A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.","Coronary heart disease","8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls","18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls","Xq23","intergenic","CHRDL1",null,null,"ENSG00000101938",null,null,"rs5943057-?","rs5943057",0,5943057,"intron_variant",0,"NR",{"v":9e-07,"d":"9.00E-07"},6.04575749056067,{"$nulls":3},"Illumina [574919]","N"]
[8,"rs693",2,21217490,"rs13392272","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","AC012361.1 - AC115619.1","ENSG00000236436","ENSG00000261012",null,132957,4695,"rs13392272-C","rs13392272",0,13392272,"intergenic_variant",1,0.607,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs74175068",2,27753878,"rs4665985","2017-08-03",28485404,"Jorgenson E","2017-05-09","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/28485404","Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.","Alcohol consumption (drinks per week)","23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.          ","NA","2p23.3","GCKR","GCKR - C2orf16","ENSG00000084734","ENSG00000221843",null,7327,6375,"rs4665985-C","rs4665985",0,4665985,"intergenic_variant",1,0.28,{"v":1e-06,"d":"1.00E-06"},6,"(EA, adjusted for lean body mass)",0.04,"[0.02-0.05] drinks per week increase","Affymetrix [NR] (imputed)","N"]
[14,"rs4704210",5,74639259,"rs3843482","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR",null,null,"ENSG00000113161",null,null,"rs3843482-T","rs3843482",0,3843482,"intron_variant",0,0.629,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[19,"rs9355288",6,160863532,"rs2048327","2014-07-23",24262325,"Dichgans M","2013-11-21","Stroke","www.ncbi.nlm.nih.gov/pubmed/24262325","Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.","Coronary artery disease","33,398 cases, 75,726 controls","NA","6q25.3","SLC22A3, LPAL2, LPA","SLC22A3",null,null,"ENSG00000146477",null,null,"rs2048327-C","rs2048327",0,2048327,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,1.07,"[1.05-1.10]","Illumina [575000] (imputed)","N"]
[19,"rs139399782",6,161129013,"rs59614420","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms","13,781 European ancestry individuals","NA","6q26","LPA","PLG",null,null,"ENSG00000122194",null,null,"rs59614420-A","rs59614420",0,59614420,"non_coding_transcript_exon_variant",0,null,{"v":1e-06,"d":"1.00E-06"},6,null,4.48,"[3.98-4.98] unit decrease","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[22,"rs6601599",8,11395079,"rs1478898","2016-12-08",26835600,"Hu Y","2016-02-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26835600","GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.","Morning vs. evening chronotype","38,937 European ancestry morning chronotype individuals, 50,346 European ancestry evening chronotype individuals","NA","8p23.1","NR","BLK",null,null,"ENSG00000136573",null,null,"rs1478898-?","rs1478898",0,1478898,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,{"$nulls":3},"Illumina [7427422] (imputed)","N"]
[29,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs62568184",9,107657070,"rs3905000","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-G","rs3905000",0,3905000,"intron_variant",0,0.883,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.094,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2017-02-03",27197191,"Fehringer G","2016-04-20","Cancer Res","www.ncbi.nlm.nih.gov/pubmed/27197191","Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.","Cancer (pleiotropy)","5,020 European ancestry lung cancer cases, 3,718 European ancestry lung adenocarcinoma cases, 3,422 European ancestry lung squamous cell carcinoma cases, 15,414 European ancestry colorectal cancer cases, 10,809 European ancestry breast cancer cases, 4,939 European ancestry estrogen receptor negative breast cancer cases, 1,098 European ancestry ovarian cancer cases, 2,556 European ancestry serous ovarian cancer cases, 715 European ancestry ovarian endometrioid carcinoma cases, 9,710 European ancestry prostate cancer cases, 4,450 European ancestry aggressive prostate cancer cases,  61,820 European ancestry controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-C","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(subset analysis)",null,null,"Affymetrix, Illumina [9916564] (imputed)","N"]
[38,"rs7970695",12,121403724,"rs7953249","2013-01-30",23144326,"Kim DK","2012-11-09","Am J Respir Crit Care Med","www.ncbi.nlm.nih.gov/pubmed/23144326","Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.","Chronic obstructive pulmonary disease-related biomarkers","Up to 1,951 European ancestry smokers","NA","12q24.31","TCF1, HNF1A","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.44,{"v":1e-06,"d":"1.00E-06"},6,"(CRP)",null,null,"Illumina [588352]","N"]
[42,"rs3764261",16,56989590,"rs247616","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,10815,6172,"rs247616-C","rs247616",0,247616,"intergenic_variant",1,0.678,{"v":1e-06,"d":"1.00E-06"},6,null,1.04,"[1.03-1.06]","Affymetrix [9149595] (imputed)","N"]
[42,"rs3764261",16,56991363,"rs183130","2018-10-24",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","188,577 European and other ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,12588,4399,"rs183130-?","rs183130",0,183130,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(Yoruban)",null,null,"Illumina [4454201] (imputed)","N"]
[50,"rs4803748",19,45242740,"rs2927439","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,13425,8222,"rs2927439-A","rs2927439",0,2927439,"intergenic_variant",1,"NR",{"v":1e-06,"d":"1.00E-06"},6,null,0.018,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157580",19,45395266,"rs157580","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs157580-?","rs157580",0,157580,"intron_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(AB1-42)",null,null,"Illumina [322557]","N"]
[50,"rs157595",19,45414451,"rs439401","2011-01-12",21123754,"Kim S","2010-12-01","Neurology","www.ncbi.nlm.nih.gov/pubmed/21123754","Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.","Alzheimer's disease biomarkers","96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls","NA","19q13.32","LOC100129500","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-?","rs439401",0,439401,"non_coding_transcript_exon_variant",0,"NR",{"v":1e-06,"d":"1.00E-06"},6,"(AB1-42)",null,null,"Illumina [322557]","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.883,{"v":1e-06,"d":"1.00E-06"},6,"(Hispanic)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21956653,"rs2283790","2018-04-25",23749187,"Cortes A","2013-07-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/23749187","Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.","Ankylosing spondylitis","9,069 European ancestry cases, 1,550 East Asian ancestry cases, 13,578 European ancestry controls, 1,567 East Asian ancestry controls","NA","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs2283790-G","rs2283790",0,2283790,"intron_variant",0,0.196,{"v":1e-06,"d":"1.00E-06"},6,"(EA)",1.12,null,"Illumina [128935]","N"]
[4,"1:62980399_CACA_C",1,63145439,"rs11208004","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","1p31.3","ANGPTL3","DOCK7",null,null,"ENSG00000116641",null,null,"rs11208004-A","rs11208004",0,11208004,"intron_variant",0,0.187,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Asian initial, BMI unadjusted)",0.0494,"[0.029-0.07] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[12,"rs59950280",4,3452345,"rs59950280","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","4p16.3","HGFAC","HGFAC - DOK7","ENSG00000109758","ENSG00000175920",null,1123,12693,"rs59950280-A","rs59950280",0,59950280,"intergenic_variant",1,0.341,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.033,"[0.019-0.047] unit increase","Affymetrix [7947838] (imputed)","N"]
[14,"rs4704210",5,74656539,"rs12916","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","HMGCR, COL4A3BP",null,null,"ENSG00000113161, ENSG00000113163",null,null,"rs12916-T","rs12916",0,12916,"3_prime_UTR_variant",0,0.605,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[17,"rs59136961",6,34769765,"rs4472337","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","6p21.31","ANKS1A","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs4472337-T","rs4472337",0,4472337,"intron_variant",0,0.155,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.06,"[1.03-1.08]","Affymetrix [9149595] (imputed)","N"]
[21,"rs2126259",8,9184691,"rs6601299","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs6601299-T","rs6601299",0,6601299,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.03,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[22,"rs11250098",8,11053922,"rs28633434","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","8p23.1","NR","XKR6",null,null,"ENSG00000171044",null,null,"rs28633434-A","rs28633434",0,28633434,"intron_variant",0,0.4823,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.0140695125,"[0.0083-0.0199] unit decrease","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.077,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1800978",9,107672365,"rs2777795","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)","2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-?","rs2777795",0,2777795,"intron_variant",0,0.8982,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(women)",0.02,"[0.012-0.028] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[35,"rs11216275",11,116973929,"rs12269901","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","HDL cholesterol","7,813 African American individuals","4,323 African American and Afro-Caribbean individuals","11q23.3","intergenic","AP000936.1",null,null,"ENSG00000224077",null,null,"rs12269901-C","rs12269901",0,12269901,"intron_variant",0,0.68,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,0.069,"[0.041-0.097] unit increase","Affymetrix [~ 2740000] (imputed)","N"]
[35,"rs11216275",11,116973929,"rs12269901","2018-07-19",29782485,"Rueger S","2018-05-21","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29782485","Evaluation and application of summary statistic imputation to discover new height-associated loci.","Height","253,288 European ancestry individuals","336,474 European ancestry individuals","11q23.3","NR","AP000936.1",null,null,"ENSG00000224077",null,null,"rs12269901-C","rs12269901",0,12269901,"intron_variant",0,0.290399365247289,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"NR [9276018] (imputed)","N"]
[41,"rs12907378",15,58635583,"rs4775031","2012-11-13",20125193,"Cirulli ET","2010-02-03","Eur J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/20125193","Common genetic variation and performance on standardized cognitive tests.","Cognitive performance","Up to 813 European ancestry individuals, up to 167 East Asian ancestry individuals, up to 7 Hispanic/Latin American individuals, up to 74 South Asian ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs4775031-?","rs4775031",0,4775031,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(TrailsB)",null,null,"Illumina [up to 563855]","N"]
[47,"rs9964112",18,47328029,"rs617619","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","18q21.1","NR","ACAA2, AC090227.1",null,null,"ENSG00000167315, ENSG00000266997",null,null,"rs617619-?","rs617619",0,617619,"intron_variant",0,"NR",{"v":2e-06,"d":"2.00E-06"},5.69897000433601,{"$nulls":3},"Affymetrix [NR]","N"]
[50,"rs566486324",19,45351746,"rs1871047","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","PVRL2","NECTIN2",null,null,"ENSG00000130202",null,null,"rs1871047-A","rs1871047",0,1871047,"intron_variant",0,0.619781,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.270037,"[1.15-1.39]","Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist-hip ratio","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.8482,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(EA, women)",0.0308,"[0.018-0.044] unit increase","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[50,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,0.379,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(AA)",0.125,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.789,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(AA)",0.151,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157595",19,45414451,"rs439401","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs439401-T","rs439401",0,439401,"non_coding_transcript_exon_variant",0,0.543,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.074,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","19q13.32","APOC2, APOE, APOC4, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.21,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(CRP)",0.28,"[NR] mg/L decrease","Affymetrix [408775]","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(East Asian)",0.132,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs12721109",19,45447221,"rs12721109","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC4-APOC2, APOC4",null,null,"ENSG00000224916, ENSG00000267467",null,null,"rs12721109-G","rs12721109",0,12721109,"intron_variant",0,0.99,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Hispanic)",0.439,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206172,"rs516246","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-A","rs516246",0,516246,"intron_variant",0,0.272,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Vitamin B12 )",0.03,"[NR] pmol/L increase","Illumina [899892]","N"]
[57,"rs5754102",22,21939675,"rs5754217","2011-04-07",21408207,"Chung SA","2011-03-03","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21408207","Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.","Systemic lupus erythematosus","811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls","NA","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754217-T","rs5754217",0,5754217,"intron_variant",0,0.19,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(anti-dsDNA +)",1.38,"[1.21-1.57]","Illumina [421318] (imputed)","N"]
[57,"rs5754102",22,21939675,"rs5754217","2017-10-09",19838195,"Gateva V","2009-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19838195","A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.","Systemic lupus erythematosus","1,310 European ancestry cases, 7,859 European ancestry controls","1,963 European ancestry cases, 4,329 European ancestry controls","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754217-T","rs5754217",0,5754217,"intron_variant",0,0.19,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,null,1.2,"[1.13-1.27]","Illumina [~ 2100000] (imputed)","N"]
[57,"rs5754102",22,21976934,"rs7444","2017-02-19",27399966,"Morris DL","2016-07-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27399966","Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.","Systemic lupus erythematosus","1,659 Chinese ancestry cases, 3,398 Chinese ancestry controls, 4,036 European ancestry cases, 6,959 European ancestry controls","3,043 Chinese ancestry cases, 5,074 Chinese ancestry controls, 2,643 European ancestry cases, 9,032 European ancestry controls","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs7444-?","rs7444",0,7444,"3_prime_UTR_variant",0,0.519,{"v":2e-06,"d":"2.00E-06"},5.69897000433601,"(Chinese)",1.23,"[NR]","NR [6344733] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63025942,"rs2131925","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p31.3","NR","DOCK7",null,null,"ENSG00000116641",null,null,"rs2131925-G","rs2131925",0,2131925,"intron_variant",0,0.371,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.067,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[8,"2:21266774_GGCAGCGCCA_G",2,21263900,"rs1367117","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB",null,null,"ENSG00000084674",null,null,"rs1367117-G","rs1367117",0,1367117,"missense_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.018,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[8,"rs668948",2,21303616,"rs568938","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,36671,43173,"rs568938-C","rs568938",0,568938,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2017-03-31",27702941,"Cornelis MC","2016-10-03","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/27702941","Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.","Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio)","5,323 European ancestry individuals","824 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.38,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,4.69,"Z-score decrease","Illumina [~ 31000000] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Palmitic acid (16:0) levels","8,961 European ancestry individuals",null,"2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1261,"unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs145508558",2,27789861,"rs965813","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","AC109829.1","C2orf16",null,null,"ENSG00000221843",null,null,"rs965813-A","rs965813",0,965813,"missense_variant",0,0.333,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0415,"[0.024-0.059] unit decrease","Affymetrix [at least 805769] (imputed)","N"]
[12,"rs36205397",4,3473139,"rs6831256","2018-07-19",29782485,"Rueger S","2018-05-21","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/29782485","Evaluation and application of summary statistic imputation to discover new height-associated loci.","Height","253,288 European ancestry individuals","336,474 European ancestry individuals","4p16.3","NR","DOK7",null,null,"ENSG00000175920",null,null,"rs6831256-G","rs6831256",0,6831256,"intron_variant",0,0.424226395133562,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,{"$nulls":3},"NR [9276018] (imputed)","N"]
[14,"rs4704210",5,74602699,"rs1423527","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","5q13.3","NR","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,69996,13281,"rs1423527-C","rs1423527",0,1423527,"regulatory_region_variant",1,0.446,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[14,"rs253412",5,74997756,"rs10057967","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related diseases, mortality and associated endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","5q13.3","NR","POC5",null,null,"ENSG00000152359",null,null,"rs10057967-?","rs10057967",0,10057967,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,{"$nulls":3},"Affymetrix [NR]","N"]
[14,"rs56912706",5,75003678,"rs2307111","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes (adjusted for BMI)","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","5q13.3","POC5","POC5",null,null,"ENSG00000152359",null,null,"rs2307111-T","rs2307111",0,2307111,"missense_variant",0,0.597,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.03,"[1.02-1.05]","Affymetrix, Illumina [247470]","N"]
[16,"rs1235162",6,29153155,"rs3130746","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tuberculosis","4,426 European ancestry cases, 84,290 European ancestry controls","NA","6p22.1","NR","OR2J4P - AL645937.3","ENSG00000218297","ENSG00000230598",null,2933,27508,"rs3130746-?","rs3130746",0,3130746,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1783,"[0.1-0.25] unit increase","Illumina [at least 560000] (imputed)","N"]
[17,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Hip circumference adjusted for BMI","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.8425,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0298,"[0.017-0.042] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[17,"rs59136961",6,34827085,"rs9469913","2019-04-03",30778226,"Justice AE","2019-02-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/30778226","Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.","Waist-to-hip ratio adjusted for BMI (additive genetic model)","up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women","up to 62,368 European ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs9469913-A","rs9469913",0,9469913,"missense_variant",0,0.8474,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0251,"[0.015-0.036] unit increase","Affymetrix, Illumina [at least 228985]","N"]
[20,"7:73042302_GCTTT_G",7,72864869,"rs714052","2010-09-10",20657596,"Johansen CT","2010-07-25","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20657596","Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.","Hypertriglyceridemia","463 European ancestry cases, 1,197 European ancestry controls","NA","7q11.23","MLXIPL","BAZ1B",null,null,"ENSG00000009954",null,null,"rs714052-?","rs714052",0,714052,"intron_variant",0,0.87,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,2.27,"[1.61-3.23]","Affymetrix [~ 2100000] (imputed)","N"]
[20,"rs34121855",7,72885810,"rs6976930","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","7q11.23","PMS2P5","BAZ1B",null,null,"ENSG00000009954",null,null,"rs6976930-G","rs6976930",0,6976930,"intron_variant",0,0.8132,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0351,"[0.02-0.05] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[20,"rs34121855",7,72934510,"rs7811265","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","7q11.23","NR","BAZ1B",null,null,"ENSG00000009954",null,null,"rs7811265-A","rs7811265",0,7811265,"intron_variant",0,0.905,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.116,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs615632",8,9814411,"rs656319","2013-01-16",23049088,"Meng W","2012-10-09","Invest Ophthalmol Vis Sci","www.ncbi.nlm.nih.gov/pubmed/23049088","A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.","Myopia (pathological)","187 European ancestry cases, 1064 European ancestry controls",null,"8p23.1","intergenic","LINC00599 - AC034111.1","ENSG00000253230","ENSG00000260093",null,51535,93584,"rs656319-?","rs656319",0,656319,"intergenic_variant",1,0.549,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,null,"[NR]","Affymetrix, Illumina [152234]","N"]
[22,"rs6601599",8,11433909,"rs2898290","2018-09-14",27618452,"Ehret GB","2016-09-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618452","The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.","Diastolic blood pressure","up to 201,529 European ancestry individuals","up to 140,886 European ancestry individuals","8p23.1","BLK, GATA4","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.167,"[0.096-0.238] mm Hg increase","Affymetrix, Illumina, Perlegen [128272]","N"]
[23,"rs4921915",8,18272881,"rs1495741","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-G","rs1495741",0,1495741,"regulatory_region_variant",1,0.501,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.066,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18273300,"rs1495743","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14572,111511,"rs1495743-G","rs1495743",0,1495743,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.023,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[24,"rs2326077",8,59377357,"rs6471717","2017-03-10",27094239,"Joshi AD","2016-04-16","Gastroenterology","www.ncbi.nlm.nih.gov/pubmed/27094239","Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.","Gallstone disease","8,720 European ancestry cases,  55,152 European ancestry controls","6,489 European ancestry cases, 62,797 European ancestry controls, 1,499 African American cases, 9,145 African American controls, 1,056 Hispanic cases, 2,403 Hispanic controls","8q12.1","CYP7A1, UBXN2B","UBXN2B - CYP7A1","ENSG00000215114","ENSG00000167910",null,13297,25380,"rs6471717-G","rs6471717",0,6471717,"intergenic_variant",1,0.35,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",1.11,"[1.08–1.14]","Affymetrix, Illumina [at least 2305318] (imputed)","N"]
[26,"rs2954021",8,126482077,"rs2954021","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954021-A","rs2954021",0,2954021,"intron_variant",0,0.467,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126488250,"rs2980869","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","22,526 East Asian ancestry individuals","37,842 East Asian ancestry individuals","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980869-T","rs2980869",0,2980869,"intron_variant",0,0.56,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.045,"[0.025-0.065] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2016-09-12",26343387,"Nikpay M","2015-09-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/26343387","A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.","Coronary artery disease","42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.551395,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.04,"[1.03- 1.06]","Affymetrix, Illumina [8600000] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.076,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126490972,"rs2954029","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954029-A","rs2954029",0,2954029,"intron_variant",0,0.491,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs35309034",8,126498828,"rs4870941","2019-02-08",30593698,"Hubel C","2018-12-28","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/30593698","Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.","Fat-free mass","70,700 European ancestry female individuals, 85,261 European ancestry male individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs4870941-?","rs4870941",0,4870941,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(male)",0.1938,"[0.11-0.28] unit decrease","Affymetrix [7794483] (imputed)","N"]
[26,"rs35309034",8,126504726,"rs6987702","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","8q24.13","TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs6987702-G","rs6987702",0,6987702,"intron_variant",0,0.29,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.07,"[NR] s.d. increase","Affymetrix, Illumina [up to 600000]","N"]
[29,"rs4149307",9,107591272,"rs2853579","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2853579-G","rs2853579",0,2853579,"synonymous_variant",0,0.874,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",0.033,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs56343119",9,136323754,"rs4962153","2017-03-31",27694959,"Bonder MJ","2016-10-03","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27694959","The effect of host genetics on the gut microbiome.","Gut microbiota (functional units)","984 European ancestry individuals","530 European ancestry individuals","9q34.2","ADAMTS13, CACFD1, SLC2A6","ADAMTS13, ADAMTS13",null,null,"ENSG00000281244, ENSG00000160323",null,null,"rs4962153-A","rs4962153",0,4962153,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(GO:0048598|BP|03|embryonic morphogenesis)",4.6572533,"Z-score decrease","Illumina [8100000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","Body mass index (joint analysis main effects and smoking interaction)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(women)",null,null,"Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.4106,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA, women)",0.0225,"[0.013-0.032] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[35,"rs2072560",11,116653296,"rs2075290","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs2075290-C","rs2075290",0,2075290,"intron_variant",0,0.187,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(South Asian)",0.332,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs12721026",11,116936871,"rs56751865","2018-01-29",29198719,"Shaffer JR","2017-11-30","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/29198719","Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment.","Lobe attachment (rater scored)","1791 European ancestry individuals, 5,062 Hispanic individuals, 2,857 Han Chinese ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs56751865-?","rs56751865",0,56751865,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Chinese)",0.1026,"[0.06-0.146] unit decrease","Illumina [at least 7383741] (imputed)","N"]
[35,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.028,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111932800,"rs7137828","2018-12-10",29227965,"Pilling LC","2017-12-01","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/29227965","Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.","Parental longevity (both parents in top 10%)","7,182 cases, 79,767 controls","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,{"$nulls":3},"Affymetrix [11535925] (imputed)","N"]
[37,"rs4766578",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.266,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[37,"rs233716",12,113031543,"rs233721","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","12q24.13","NR","RPH3A",null,null,"ENSG00000089169",null,null,"rs233721-?","rs233721",0,233721,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0399,"[0.023-0.057] unit increase","Illumina [at least 560000] (imputed)","N"]
[41,"rs28607776",15,58581370,"rs12148399","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs12148399-T","rs12148399",0,12148399,"intron_variant",0,0.888,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.1,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.64,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.071,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58680178,"rs261291","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs261291-T","rs261291",0,261291,"intron_variant",0,0.612,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.06,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs55696635",15,58712203,"rs11857380","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs11857380-C","rs11857380",0,11857380,"5_prime_UTR_variant",0,0.131,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Weight )",0.03,"[NR] kg increase","Illumina [899892]","N"]
[41,"rs1077835",15,58723675,"rs1800588","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","18,421 East Asian ancestry individuals","38,060 East Asian ancestry individuals","15q21.3","LIPC","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-T","rs1800588",0,1800588,"intron_variant",0,0.41,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.078,"[0.045-0.111] unit increase","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[42,"rs9921780",16,56950210,"rs9925265","2019-03-29",30741946,"Gialluisi A","2019-02-11","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30741946","Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.","Reading ability (multivariate)","up to 3,468 European ancestry individuals","NA","16q13","NR","SLC12A3 - HERPUD1","ENSG00000070915","ENSG00000051108",null,448,15750,"rs9925265-?","rs9925265",0,9925265,"intergenic_variant",1,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,{"$nulls":3},"Illumina [up to 6969139] (imputed)","N"]
[42,"rs755671262",16,56969148,"rs2217332","2010-09-13",20694148,"Zabaneh D","2010-08-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20694148","A genome-wide association study of the metabolic syndrome in Indian Asian men.","Metabolic syndrome","2,554 Indian Asian ancestry individuals","2,240 Indian Asian ancestry individuals","16q13","HERPUD1","HERPUD1",null,null,"ENSG00000051108",null,null,"rs2217332-?","rs2217332",0,2217332,"missense_variant",0,0.19,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(HDL)",null,null,"Illumina [308011]","N"]
[42,"rs3764261",16,56987369,"rs56156922","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,8594,8393,"rs56156922-T","rs56156922",0,56156922,"regulatory_region_variant",1,0.709,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Hispanic)",0.078,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs3816117",16,56995236,"rs1800775","2017-11-01",17463246,"Saxena R","2007-04-26","Science","www.ncbi.nlm.nih.gov/pubmed/17463246","Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.","Apolipoprotein A1 levels","1,451 European ancestry type 2 diabetes cases and controls","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,16460,599,"rs1800775-C","rs1800775",0,1800775,"regulatory_region_variant",1,0.44,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.6,"(% variance) increase","Affymetrix [389878]","N"]
[49,"rs11882123",19,19552413,"rs4808955","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Tonsillectomy","60,098 European ancestry cases, 113,323 European ancestry controls","NA","19p13.11","NR","GATAD2A",null,null,"ENSG00000167491",null,null,"rs4808955-?","rs4808955",0,4808955,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.0401,"[0.023-0.057] unit decrease","Illumina [at least 560000] (imputed)","N"]
[49,"rs7245672",19,19692579,"rs7252981","2017-10-09",28199695,"Jones AV","2017-04-01","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28199695","GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.","Perceived unattractiveness to mosquitoes","16,576 European ancestry individuals","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs7252981-T","rs7252981",0,7252981,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.112447,"[0.065-0.16] unit decrease","Illumina [7433384] (imputed)","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.12,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","Triglycerides","17,100 European ancestry individuals, 715 Orcadian individuals","NA","19p13.11","NCAN","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-G","rs2304130",0,2304130,"splice_region_variant",0,0.07,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.1,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.036,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.034,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs566486324",19,45348253,"rs10426423","2019-04-17",30636644,"Nazarian A","2019-01-12","Alzheimers Res Ther","www.ncbi.nlm.nih.gov/pubmed/30636644","Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.","Alzheimer's disease","952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls","NA","19q13.32","PVRL2","BCAM - NECTIN2","ENSG00000187244","ENSG00000130202",null,23575,1179,"rs10426423-C","rs10426423",0,10426423,"TF_binding_site_variant",1,0.620314,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.265674,"[1.15-1.38]","Affymetrix, Illumina [2928658] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2013-04-19",23326517,"Holliday EG","2013-01-11","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23326517","Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.","Age-related macular degeneration","3,772 European ancestry cases, 16,033 European ancestry controls","264 Asian ancestry cases, 3,926 Asian ancestry controls","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.86,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.21,"[1.11 - 1.32]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[50,"rs2238681",19,45403412,"rs1160985","2016-11-24",26763881,"Kurano M","2016-01-14","J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/26763881","Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.","LDL cholesterol levels","2,994 Japanese ancestry individuals","6,805 Korean ancestry individuals","19q13.32","APOE, TOMM40","TOMM40",{"$nulls":5},"rs1160985-?","rs1160985",0,1160985,"intron_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.16,"[0.095-0.225] unit decrease","Illumina [1294241]","N"]
[50,"rs2238681",19,45403412,"rs1160985","2018-12-06",30319691,"Liu C","2018-09-24","Front Genet","www.ncbi.nlm.nih.gov/pubmed/30319691","Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.","Cerebrospinal fluid AB1-42 levels","235 early mild cognitive impairment cases, 249 late mild cognitive impairment cases, 47 Alzheimer's disease cases, 281 controls.","NA","19q13.32","Intergenic","TOMM40",{"$nulls":5},"rs1160985-?","rs1160985",0,1160985,"intron_variant",0,null,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,131.1304,"[NR] unit decrease","Illumina [575353]","N"]
[50,"rs2238681",19,45405062,"rs1038026","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","TOMM40",{"$nulls":5},"rs1038026-A","rs1038026",0,1038026,"3_prime_UTR_variant",0,0.536,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(EA)",0.018,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,"NR",{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,0.02,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.897,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(East Asian)",0.118,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206462,"rs681343","2017-05-12",27992413,"Ji SG","2016-12-19","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27992413","Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.","Primary sclerosing cholangitis","2,871 European ancestry cases, 12,019 European ancestry controls","1,925 European ancestry cases, 7,936 European ancestry controls","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs681343-T","rs681343",0,681343,"stop_gained",0,0.46,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.11,"[1.06-1.17]","Affymetrix, Illumina [7891602] (imputed)","N"]
[55,"rs6129762",20,39724338,"rs6065311","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","20q12","MAFB","TOP1",null,null,"ENSG00000198900",null,null,"rs6065311-T","rs6065311",0,6065311,"intron_variant",0,0.194,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Asian initial, BMI unadjusted)",0.0485,"[0.028-0.069] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[55,"rs6129762",20,39724338,"rs6065311","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","LDL cholesterol levels","32,285 East Asian ancestry individuals, 173,082 European ancestry individuals","8,478 Chinese ancestry individuals","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6065311-T","rs6065311",0,6065311,"intron_variant",0,0.194,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(Asian initial, BMI unadjusted)",0.0485,"[0.028-0.069] unit decrease","Affymetrix, Illumina [~ 1900000] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-04-05",29632382,"Mahajan A","2018-04-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29632382","Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.","Type 2 diabetes","up to 48,286 European ancestry cases, up to 250,671 European ancestry controls","NA","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.035,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,null,1.09,"[1.04-1.13]","Affymetrix, Illumina [247470]","N"]
[57,"rs5754102",22,21973319,"rs4821116","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","HDL cholesterol levels","25,169 East Asian ancestry individuals","45,953 East Asian ancestry individuals","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs4821116-T","rs4821116",0,4821116,"intron_variant",0,0.39,{"v":3e-06,"d":"3.00E-06"},5.52287874528033,"(BMI unadjusted)",0.044,"[0.026-0.062] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[3,"rs12067569",1,55529187,"rs505151","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","22,814 East Asian ancestry individuals","57,490 East Asian ancestry individuals","1p32.3","PCSK9","PCSK9",null,null,"ENSG00000169174",null,null,"rs505151-A","rs505151",0,505151,"missense_variant",0,0.94,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(BMI unadjusted)",0.102,"[0.059-0.145] unit decrease","Affymetrix, Illumina [~ 2400000] (imputed)","N"]
[4,"1:62980399_CACA_C",1,63049593,"rs1748195","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Crohn's disease","12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls","NA","1p31.3","ANGPTL3, AL138847.1, DOCK7, USP1","DOCK7",null,null,"ENSG00000116641",null,null,"rs1748195-?","rs1748195",0,1748195,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [9560910] (imputed)","N"]
[5,"rs3832016",1,109818530,"rs646776","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","1p13.3","CELSR2, PSRC1, SORT1","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,157,3648,"rs646776-C","rs646776",0,646776,"regulatory_region_variant",1,0.19,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(chol, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[8,"rs668948",2,21288321,"rs562338","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,21376,58468,"rs562338-A","rs562338",0,562338,"intergenic_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.022,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2012-12-21",23022100,"Franceschini N","2012-09-26","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23022100","Discovery and fine mapping of serum protein loci through transethnic meta-analysis.","Serum total protein level","Up to 25,539 European ancestry individuals, 10,168 Japanese ancestry individuals","NA","2p23.3","FNDC4, GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.56,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Japanese)",0.031,"[0.017-0.045] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[14,"rs4555772",5,74302658,"rs4555772","2013-06-06",23362303,"Wu JH","2013-01-29","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23362303","Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.","Stearic acid (18:0) levels","8,961 European ancestry individuals",null,"5q13.3","GCNT4","AC116337.3, AC093259.1",null,null,"ENSG00000249856, ENSG00000249157",null,null,"rs4555772-A","rs4555772",0,4555772,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0888,"unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[14,"rs4704210",5,74605220,"rs10056811","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","5q13.3","intergenic","ANKRD31 - AC008897.2","ENSG00000145700","ENSG00000247372",null,72517,10760,"rs10056811-A","rs10056811",0,10056811,"intergenic_variant",1,0.3466,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0274,"[0.016-0.039] unit increase","NR [8041861] (imputed)","N"]
[14,"rs888789",5,74988369,"rs888789","2014-11-27",24861553,"Wen W","2014-05-26","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/24861553","Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.","Body mass index","82,438 East Asian ancestry individuals, 4,301 South East Asian ancestry individuals","Up to 47,352 East Asian ancestry individuals","5q13.3","FLJ35779","POC5",null,null,"ENSG00000152359",null,null,"rs888789-A","rs888789",0,888789,"intron_variant",0,0.46,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.024,"[0.014-0.034] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[14,"rs253412",5,75015242,"rs2112347","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,1936,33153,"rs2112347-T","rs2112347",0,2112347,"intergenic_variant",1,0.629,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA, women)",0.0228,"[0.013-0.033] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[17,"rs59136961",6,34773727,"rs2395607","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs2395607-T","rs2395607",0,2395607,"intron_variant",0,0.1724,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.0282,"[0.016-0.04] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[22,"rs11250098",8,10818607,"rs11250098","2016-12-08",26835600,"Hu Y","2016-02-02","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/26835600","GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.","Morning vs. evening chronotype","38,937 European ancestry morning chronotype individuals, 50,346 European ancestry evening chronotype individuals","NA","8p23.1","NR","XKR6",null,null,"ENSG00000171044",null,null,"rs11250098-?","rs11250098",0,11250098,"intron_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [7427422] (imputed)","N"]
[22,"rs6601599",8,11433909,"rs2898290","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","8p23.1","BLK, LINC00208","LINC00208",null,null,"ENSG00000170983",null,null,"rs2898290-T","rs2898290",0,2898290,"non_coding_transcript_exon_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.26,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[29,"rs2740488",9,107661742,"rs2740488","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs2740488-A","rs2740488",0,2740488,"intron_variant",0,0.817,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.079,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1800978",9,107665978,"rs1800978","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs1800978-C","rs1800978",0,1800978,"5_prime_UTR_variant",0,0.87,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.033,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[30,"rs115478735",9,136155000,"rs635634","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Stroke","40,585 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,154 African American controls, 365 Asian ancestry cases, 333 Asian ancestry controls, 865 Latin American cases, 692 Latin American controls","NA","9q34.2","ABO","ABO - RF00019","ENSG00000175164","ENSG00000200572",null,4208,23043,"rs635634-?","rs635634",0,635634,"regulatory_region_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47781306,"rs7927771","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","11p11.2","NR","FNBP4",null,null,"ENSG00000109920",null,null,"rs7927771-A","rs7927771",0,7927771,"intron_variant",0,0.6579,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0129,"[0.0074-0.0184] unit decrease","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.778,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Asian initial, BMI unadjusted)",0.0449,"[0.026-0.064] unit decrease","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2018-07-13",29212154,"Lin E","2017-09-16","Oncotarget","www.ncbi.nlm.nih.gov/pubmed/29212154","Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.","Metabolic syndrome","1,811 Taiwanese Han Chinese ancestry cases, 8,489 Taiwanese Han Chinese ancestry controls","NA","11q23.3","APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-?","rs662799",0,662799,"intergenic_variant",1,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(additive)",1.25,"[1.14-1.37]","Affymetrix [583469]","N"]
[35,"rs236911",11,117085270,"rs236911","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","PCSK7",null,null,"ENSG00000160613",null,null,"rs236911-A","rs236911",0,236911,"non_coding_transcript_exon_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.023,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[36,"rs2241212",12,109980516,"rs7956536","2018-08-10",26362759,"Rothwell S","2015-09-11","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/26362759","Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.","Polymyositis","931 European ancestry cases, 15,651 European ancestry controls",null,"12q24.11","UBE3B, MMAB","UBE3B - MMAB","ENSG00000151148","ENSG00000139428",null,6006,11026,"rs7956536-?","rs7956536",0,7956536,"regulatory_region_variant",1,0.53,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,1.25,null,"Illumina [90536]","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (large artery atherosclerosis)","4,373 European ancestry cases, 406,111 European ancestry controls, 1,626 East Asian ancestry cases, 28,195 East Asian ancestry controls, 355 South Asian ancestry cases, 6,707 South Asian ancestry controls, 259 African American cases, 15,146 African American controls, 34 Asian ancestry cases, 333 Asian ancestry controls, 41 Latin American cases, 692 Latin American controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Latino)",0.609,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Systolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.259,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[37,"rs4766578",12,111932800,"rs7137828","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.12","NR","ATXN2",null,null,"ENSG00000204842",null,null,"rs7137828-C","rs7137828",0,7137828,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(Latino)",0.613,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[41,"rs1601935",15,58671765,"rs1601935","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1601935-G","rs1601935",0,1601935,"intron_variant",0,0.33,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.08,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58679668,"rs7350789","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs7350789-G","rs7350789",0,7350789,"intron_variant",0,0.628,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.104,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.52,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(AA)",0.098,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs7239952",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,0.675,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.31,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs142158911",19,11189764,"rs73015011","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","SMARCA4",null,null,"ENSG00000127616",null,null,"rs73015011-T","rs73015011",0,73015011,"missense_variant",0,0.985,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(East Asian)",0.308,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs3761077",19,19336608,"rs2238675","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","NCAN",null,null,"ENSG00000130287",null,null,"rs2238675-C","rs2238675",0,2238675,"intron_variant",0,0.878,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(EA)",0.038,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs58542926",19,19721722,"rs12610185","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","19p13.11","PBX4","PBX4",null,null,"ENSG00000105717",null,null,"rs12610185-A","rs12610185",0,12610185,"intron_variant",0,0.053,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(TG )",0.03,"[NR] mg/dL increase","Illumina [899892]","N"]
[50,"rs142042446",19,45395619,"rs2075650","2016-09-27",26632684,"Dong J","2015-11-01","Medicine (Baltimore)","www.ncbi.nlm.nih.gov/pubmed/26632684","Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.","Sense of smell","6,252 European ancestry individuals","NA","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.13,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.04,"[0.02-0.06] ln(smell score+1) increase","Affymetrix, Illumina [2543887] (imputed)","N"]
[50,"rs1065853",19,45415640,"rs445925","2011-10-07",21909108,"Bis JC","2011-09-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21909108","Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.","Carotid intima media thickness","Up to 31,211 European ancestry individuals","10,553 European ancestry individuals, 687 Orcadian individuals","19q13.32","APOC1","AC011481.3",null,null,"ENSG00000267282",null,null,"rs445925-G","rs445925",0,445925,"non_coding_transcript_exon_variant",0,0.89,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,"(plaque)",1.22,"[1.12-1.32]","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[55,"rs2179372",20,39678289,"rs6016505","2017-06-27",28560309,"Lee E","2017-04-23","Alzheimers Dement (Amst)","www.ncbi.nlm.nih.gov/pubmed/28560309","Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.","Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction)","242 European ancestry individuals","NA","20q12","TOP1","TOP1",null,null,"ENSG00000198900",null,null,"rs6016505-?","rs6016505",0,6016505,"intron_variant",0,null,{"v":4e-06,"d":"4.00E-06"},5.39794000867203,{"$nulls":3},"Illumina [5908215] (imputed)","N"]
[57,"rs5754102",22,21979096,"rs11089637","2019-01-25",30423114,"Laufer VA","2018-11-13","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/30423114","Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.","Rheumatoid arthritis","916 African American cases, 1,392 African American controls,","4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls","22q11.21","UBE2L3, YDJC","UBE2L3 - YDJC","ENSG00000185651","ENSG00000161179",null,773,3282,"rs11089637-T","rs11089637",0,11089637,"intergenic_variant",1,"NR",{"v":4e-06,"d":"4.00E-06"},5.39794000867203,null,0.0506095,"[-0.02104-0.12226] unit decrease","Illumina [8380626] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2013-01-30",23118302,"Chu AY","2012-11-01","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/23118302","Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.","Lipoprotein-associated phospholipase A2 activity and mass","6,851 European ancestry individuals","13,664 European ancestry individuals","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,0.44,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(mass)",5.3E-3,"[-0.00215-0.01275] ng/ml decrease","Illumina [796174]","N"]
[9,"rs1260326",2,27730940,"rs1260326","2018-09-28",30108127,"Hoffmann TJ","2018-08-14","Genetics","www.ncbi.nlm.nih.gov/pubmed/30108127","A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.","Body mass index","315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals","431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals","2p23.3","NR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-T","rs1260326",0,1260326,"missense_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.012,"[NR] unit decrease","Affymetrix [at least 28613428] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2013-09-04",20139978,"Kamatani Y","2010-02-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20139978","Genome-wide association study of hematological and biochemical traits in a Japanese population.","Urate levels","8,868 Japanese ancestry individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-T","rs780094",0,780094,"intron_variant",0,0.57,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.069,"[0.040,0.098] unit increase","Illumina [561583]","N"]
[9,"rs1260326",2,27742603,"rs780093","2012-08-20",22747683,"Eriksson N","2012-06-30","BMC Med Genet","www.ncbi.nlm.nih.gov/pubmed/22747683","Genetic variants associated with breast size also influence breast cancer risk.","Breast size","16,175 European ancestry female individuals","NA","2p23.3","SLC4A1AP","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,0.416,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.072,"[0.041-0.103] cup size increase","Illumina [7422970] (imputed)","N"]
[18,"rs6934962",6,116399372,"rs6932852","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q22.1","NR","FRK - NT5DC1","ENSG00000111816","ENSG00000178425",null,17451,22640,"rs6932852-C","rs6932852",0,6932852,"intergenic_variant",1,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs4149307",9,107589580,"rs4149309","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","88,192 cases, 162,544 controls","34,541 cases, 261,984 controls","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149309-A","rs4149309",0,4149309,"intron_variant",0,0.8413,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.0418,"[0.024-0.06] unit decrease","NR [8041861] (imputed)","N"]
[29,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA, women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[29,"rs1800978",9,107672365,"rs2777795","2017-08-22",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Waist-to-hip ratio adjusted for BMI in active individuals","1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs2777795-G","rs2777795",0,2777795,"intron_variant",0,0.9005,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(women)",0.0499,"[0.029-0.071] unit increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA, women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(women)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index in physically active individuals","1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals","4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.4016,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(men)",0.0276,"[0.016-0.039] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[34,"rs144023941",11,75455309,"rs600626","2014-11-15",24823311,"Guan W","2014-05-13","Circ Cardiovasc Genet","www.ncbi.nlm.nih.gov/pubmed/24823311","Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.","Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)","8,631 European ancestry individuals","NA","11q13.5","MOGAT2","RN7SL786P - AP001922.1","ENSG00000263993","ENSG00000247867",null,1838,14191,"rs600626-A","rs600626",0,600626,"regulatory_region_variant",1,0.827,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.07,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2015-07-10",25378659,"Lemaitre RN","2014-11-06","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/25378659","Genetic loci associated with circulating levels of very long-chain saturated fatty acids.","Very long-chain saturated fatty acid levels (fatty acid 20:0)","10,129 European ancestry individuals","NA","11q23.3","ZNF259","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,4.581,"[NR] Z score increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2017-09-28",28714975,"Nelson CP","2017-07-17","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28714975","Association analyses based on false discovery rate implicate new loci for coronary artery disease.","Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)","18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls","57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls","11q23.3","ZNF259, APOA5, APOA1","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-G","rs964184",0,964184,"3_prime_UTR_variant",0,0.163,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.05,"[1.03-1.08]","Affymetrix [9149595] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-C","rs651821",0,651821,"5_prime_UTR_variant",0,0.191,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(South Asian)",0.333,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs545274",11,116829653,"rs7120173","2012-08-17",22589738,"Fox CS","2012-05-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/22589738","Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.","Visceral adipose tissue adjusted for BMI","5,560 European ancestry female individuals, 4,997 European ancestry male individuals","NA","11q23.3","KIAA0999","SIK3",null,null,"ENSG00000160584",null,null,"rs7120173-G","rs7120173",0,7120173,"intron_variant",0,0.22,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(men)",null,null,"Affymetrix, Illumina [2500000] (imputed)","N"]
[37,"rs4766578",12,112059557,"rs11065979","2017-02-03",27197191,"Fehringer G","2016-04-20","Cancer Res","www.ncbi.nlm.nih.gov/pubmed/27197191","Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.","Cancer (pleiotropy)","5,020 European ancestry lung cancer cases, 3,718 European ancestry lung adenocarcinoma cases, 3,422 European ancestry lung squamous cell carcinoma cases, 15,414 European ancestry colorectal cancer cases, 10,809 European ancestry breast cancer cases, 4,939 European ancestry estrogen receptor negative breast cancer cases, 1,098 European ancestry ovarian cancer cases, 2,556 European ancestry serous ovarian cancer cases, 715 European ancestry ovarian endometrioid carcinoma cases, 9,710 European ancestry prostate cancer cases, 4,450 European ancestry aggressive prostate cancer cases,  61,820 European ancestry controls","NA","12q24.12","Intergenic","ATXN2-AS - BRAP","ENSG00000258099","ENSG00000089234",null,21497,20393,"rs11065979-T","rs11065979",0,11065979,"intergenic_variant",1,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(subset analysis)",null,null,"Affymetrix, Illumina [9916564] (imputed)","N"]
[37,"rs11066320",12,112684221,"rs7953257","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma-induced protein 10 levels","3,685 Finnish ancestry individuals","NA","12q24.13","NR","HECTD4",null,null,"ENSG00000173064",null,null,"rs7953257-T","rs7953257",0,7953257,"intron_variant",0,null,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.1088,"[0.062-0.156] SD units decrease","NR [10700000] (imputed)","N"]
[41,"rs1077835",15,58723675,"rs1800588","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs1800588-C","rs1800588",0,1800588,"intron_variant",0,0.596,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.073,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[42,"rs9921780",16,56950210,"rs9925265","2019-03-29",30741946,"Gialluisi A","2019-02-11","Transl Psychiatry","www.ncbi.nlm.nih.gov/pubmed/30741946","Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.","Non-word reading","3,409 European ancestry individuals","NA","16q13","Intergenic","SLC12A3 - HERPUD1","ENSG00000070915","ENSG00000051108",null,448,15750,"rs9925265-G","rs9925265",0,9925265,"intergenic_variant",1,0.53658,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.139833,"[0.08-0.2] unit increase","Illumina [6969139] (imputed)","N"]
[42,"rs3816117",16,57004889,"rs7205804","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7205804-G","rs7205804",0,7205804,"intron_variant",0,"NR",{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.02,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs737337",19,11334295,"rs4804155","2015-05-13",21347282,"Lettre G","2011-02-10","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/21347282","Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.","HDL cholesterol","7,813 African American individuals","4,323 African American and Afro-Caribbean individuals","19p13.2","DOCK6","DOCK6",null,null,"ENSG00000130158",null,null,"rs4804155-C","rs4804155",0,4804155,"intron_variant",0,0.69,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,0.0751,"[0.043-0.107] unit increase","Affymetrix [~ 2740000] (imputed)","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2016-01-27",25673413,"Locke AE","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673413","Genetic studies of body mass index yield new insights for obesity biology.","Body mass index","up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals","up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals","19p13.11","ZNF101","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.914,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.027,"[0.015-0.038] kg/m2 increase","Affymetrix, Illumina [2550021]","N"]
[50,"rs62117206",19,45247627,"rs4803750","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","RF00285 - BCL3","ENSG00000264452","ENSG00000069399",null,18312,3335,"rs4803750-A","rs4803750",0,4803750,"intergenic_variant",1,0.923,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(EA)",0.036,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs1985129",19,45382717,"rs406456","2019-02-21",30498476,"Liu H","2018-11-15","Front Endocrinol (Lausanne)","www.ncbi.nlm.nih.gov/pubmed/30498476","Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.","Low density lipoprotein cholesterol levels","139 Chinese ancestry dizygotic twin pairs","NA","19q13.32","NECTIN2","NECTIN2",null,null,"ENSG00000130202",null,null,"rs406456-?","rs406456",0,406456,"intron_variant",0,null,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,{"$nulls":3},"Illumina [7405822] (imputed)","N"]
[50,"rs157592",19,45422846,"rs56131196","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,240,7215,"rs56131196-G","rs56131196",0,56131196,"intergenic_variant",1,0.883,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","19q13.32","APOC2, APOE, APOC4, TOMM40, APOC1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-G","rs4420638",0,4420638,"intergenic_variant",1,0.21,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(TG)",0.22,"[NR] mg/dL increase","Affymetrix [408775]","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.883,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.106,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs157592",19,45422946,"rs4420638","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,340,7115,"rs4420638-A","rs4420638",0,4420638,"intergenic_variant",1,0.897,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(East Asian)",0.115,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[51,"rs35106244",19,49206172,"rs516246","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Inflammatory bowel disease","25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls","NA","19q13.33","IZUMO1, NTN5, FUT2, MAMSTR, RASIP1","FUT2",null,null,"ENSG00000176920",null,null,"rs516246-?","rs516246",0,516246,"intron_variant",0,null,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,{"$nulls":3},"Illumina [9725440] (imputed)","N"]
[51,"rs35106244",19,49206462,"rs681343","2017-09-18",28604730,"McKay JD","2017-06-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28604730","Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.","Lung adenocarcinoma","11,273 European ancestry cases,  55,483 European ancestry controls","NA","19q13.33","FUT2","FUT2",null,null,"ENSG00000176920",null,null,"rs681343-T","rs681343",0,681343,"stop_gained",0,0.526442405,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.0764673,"[1.04-1.11]","Illumina [10439017] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q13.12","NR","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-C","rs1800961",0,1800961,"missense_variant",0,0.96,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,"(Hispanic)",0.143,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21939675,"rs5754217","2013-02-21",23273568,"Yang W","2012-12-27","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/23273568","Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.","Systemic lupus erythematosus","1,656 Han Chinese ancestry cases, 3,394 Han Chinese ancestry controls","3,256 Han Chinese ancestry cases, 5,667 Han Chinese ancestry controls, 453 Thai ancestry cases, 963 Thai ancestry controls","22q11.21","UBE2L3","UBE2L3",null,null,"ENSG00000185651",null,null,"rs5754217-T","rs5754217",0,5754217,"intron_variant",0,0.56,{"v":5e-06,"d":"5.00E-06"},5.30102999566398,null,1.1236,null,"Illumina [2100739] (imputed)","N"]
[9,"rs1260326",2,27730940,"rs1260326","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs1260326-C","rs1260326",0,1260326,"missense_variant",0,0.58,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.065,"[0.038-0.092] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[9,"rs1260326",2,27741237,"rs780094","2016-01-25",25811787,"Huffman JE","2015-03-26","PLoS One","www.ncbi.nlm.nih.gov/pubmed/25811787","Modulation of genetic associations with serum urate levels by body-mass-index in humans.","Urate levels in overweight individuals","up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals","NA","2p23.3","GCKR","GCKR",null,null,"ENSG00000084734",null,null,"rs780094-C","rs780094",0,780094,"intron_variant",0,0.59,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.05,"[0.028-0.072] kg/m2 decrease","Affymetrix, Illumina [at least 188473] (imputed)","N"]
[14,"rs4704187",5,74480288,"rs4704187","2012-11-05",22952603,"Hart AB","2012-08-28","PLoS One","www.ncbi.nlm.nih.gov/pubmed/22952603","Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).","Response to amphetamines","1 American Indian ancestry individual, 18 African American individuals, 10 Asian ancestry individuals, 325 European ancestry individuals, 17 Hispanic individuals, 10 individuals","NA","5q13.3","ANKRD31","ANKRD31",null,null,"ENSG00000145700",null,null,"rs4704187-?","rs4704187",0,4704187,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(SF6)",null,null,"Affymetrix [5476100] (imputed)","N"]
[14,"rs4704210",5,74655726,"rs3846663","2009-10-15",19197348,"Lowe JK","2009-02-06","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/19197348","Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.","Quantitative traits","2,906 Kosraen individuals","NA","5q13.3","COL4A3BP, HMGCR","COL4A3BP, HMGCR",null,null,"ENSG00000113163, ENSG00000113161",null,null,"rs3846663-T","rs3846663",0,3846663,"intron_variant",0,0.39,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(TC)",0.19,"[NR] mg/dL increase","Affymetrix [408775]","N"]
[14,"rs4704210",5,74934009,"rs34341","2019-03-13",30664634,"Rask-Andersen M","2019-01-21","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30664634","Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.","Body fat distribution (leg fat ratio)","55,006 British ancestry males, 61,132 British ancestry females","112,425 British ancestry males, 133,936 British ancestry females","5q13.3","COL4A3BP, POLK","ANKDD1B",null,null,"ENSG00000189045",null,null,"rs34341-A","rs34341",0,34341,"intron_variant",0,0.438944,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(females)",0.01588,"NR unit increase (replication)","Affymetrix [25472837] (imputed)","N"]
[14,"rs56912706",5,75034387,"rs7715806","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","5q13.3","C5orf37, POC5","POC5 - SLC25A5P9","ENSG00000152359","ENSG00000251078",null,21081,14008,"rs7715806-C","rs7715806",0,7715806,"intergenic_variant",1,0.6006,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.0244,"[0.014-0.035] kg/m2 increase","Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[17,"rs59136961",6,34825662,"rs16894959","2017-05-23",25673412,"Shungin D","2015-02-12","Nature","www.ncbi.nlm.nih.gov/pubmed/25673412","New genetic loci link adipose and insulin biology to body fat distribution.","Waist circumference","up to 56,910 European ancestry men, up to 86,570 European ancestry women","up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African American/Afro-Caribbean ancestry men, 6,258 African American/Afro-Caribbean ancestry women, 2,285 South Asian ancestry men, 506 South Asian ancestry women, 195 Seychellois ancestry men, 266 Seychellois ancestry women","6p21.31","UHRF1BP1","UHRF1BP1",null,null,"ENSG00000065060",null,null,"rs16894959-T","rs16894959",0,16894959,"synonymous_variant",0,0.844,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA, women)",0.0278,"[0.016-0.04] unit decrease","Affymetrix, Illumina, Perlegen [up to 2542447] (imputed)","N"]
[18,"rs6934962",6,116399372,"rs6932852","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6q22.1","NR","FRK - NT5DC1","ENSG00000111816","ENSG00000178425",null,17451,22640,"rs6932852-C","rs6932852",0,6932852,"intergenic_variant",1,0.583,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA)",0.021,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[23,"rs4921915",8,18272881,"rs1495741","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p22","NR","NAT2 - PSD3","ENSG00000156006","ENSG00000156011",null,14153,111930,"rs1495741-G","rs1495741",0,1495741,"regulatory_region_variant",1,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.022,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs1800978",9,107653426,"rs12686004","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs12686004-G","rs12686004",0,12686004,"intron_variant",0,0.879,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[31,"rs117488242",10,5239824,"rs7087111","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10p15.1","NR","AKR1C4",null,null,"ENSG00000198610",null,null,"rs7087111-C","rs7087111",0,7087111,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.024,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[33,"11:47650138_AT_A",11,47650993,"rs3817334","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI in non-smokers","77,279 European ancestry women, 47,280 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men","16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men","11p11.2","MTCH2","MTCH2",null,null,"ENSG00000109919",null,null,"rs3817334-T","rs3817334",0,3817334,"intron_variant",0,0.3933,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(men)",0.0245,"[0.014-0.035] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2010-06-13",20453842,"Stahl EA","2010-05-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/20453842","Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.","Rheumatoid arthritis","5,539 European ancestry cases, 20,169 European ancestry controls","6,768 European ancestry cases, 8,806 European ancestry controls","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.51,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.08,"[NR]","Affymetrix, Illumina [~ 2716259] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2011-04-11",21378990,"Schunkert H","2011-03-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/21378990","Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.","Coronary heart disease","22,233 European ancestry cases, 64,762 European ancestry controls","56,682 European ancestry cases and controls","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-T","rs3184504",0,3184504,"missense_variant",0,0.44,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.07,"[1.04-1.10]","Affymetrix, Illumina [~ 2300000] (imputed)","N"]
[37,"rs4766578",12,111884608,"rs3184504","2018-07-11",29531354,"Malik R","2018-03-12","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29531354","Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.","Ischemic stroke (small-vessel)","5,386 European ancestry cases, 192,662 European ancestry controls, 5,096 East Asian ancestry cases, 28,195 East Asian ancestry controls, 314 South Asian ancestry cases, 6,707 South Asian ancestry controls, 694 African American cases, 15,146 African American controls, 134 Asian ancestry cases, 333 Asian ancestry controls, 86 Latin American cases, 692 Latin American controls","NA","12q24.12","SH2B3","SH2B3, ATXN2",null,null,"ENSG00000111252, ENSG00000204842",null,null,"rs3184504-?","rs3184504",0,3184504,"missense_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,{"$nulls":3},"NR [~ 8000000] (imputed)","N"]
[37,"rs11066320",12,112591686,"rs17630235","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals","NA","12q24.13","NR","TRAFD1 - HECTD4","ENSG00000135148","ENSG00000173064",null,273,6306,"rs17630235-G","rs17630235",0,17630235,"intergenic_variant",1,null,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Latino)",0.613,"unit decrease","Affymetrix [at least 2696785] (imputed)","N"]
[38,"rs7970695",12,121403724,"rs7953249","2017-08-03",28346442,"Phelan CM","2017-03-27","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28346442","Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.","Invasive epithelial ovarian cancer","22,406 European ancestry cases, 40,941 European ancestry controls","NA","12q24.31","NR","HNF1A-AS1",null,null,"ENSG00000241388",null,null,"rs7953249-G","rs7953249",0,7953249,"splice_region_variant",0,0.417632,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,1.0621586,"[1.0348111352015-1.09022867520121]","Illumina [11595112] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","16q13","NR","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-C","rs7499892",0,7499892,"intron_variant",0,0.794,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Hispanic)",0.084,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[49,"rs113954889",19,19263938,"rs58190593","2019-05-02",30487518,"Takeuchi F","2018-11-28","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30487518","Interethnic analyses of blood pressure loci in populations of East Asian and European descent.","Systolic blood pressure","130,777 Japanese ancestry individuals","53,008 East Asian individuals, 105,253 European ancestry individuals","19p13.11","MEF2B, MEF2BNB–MEF2B","BORCS8-MEF2B, MEF2B",null,null,"ENSG00000064489, ENSG00000213999",null,null,"rs58190593-T","rs58190593",0,58190593,"intron_variant",0,0.34,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,"(Japanese)",0.3725,"[0.21-0.53] unit increase","Illumina [6200000] (imputed)","N"]
[50,"rs395908",19,45373565,"rs395908","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs395908-G","rs395908",0,395908,"intron_variant",0,"NR",{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.023,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs142042446",19,45395619,"rs2075650","2017-08-10",28443625,"Justice AE","2017-04-26","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28443625","Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.","BMI (adjusted for smoking behaviour)","98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men","21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men","19q13.32","TOMM40","TOMM40",{"$nulls":5},"rs2075650-A","rs2075650",0,2075650,"intron_variant",0,0.8558,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.0234,"[0.013-0.034] kg/m2 increase","Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)","N"]
[50,"rs157595",19,45425460,"rs157595","2018-01-29",29212778,"van der Harst P","2017-12-06","Circ Res","www.ncbi.nlm.nih.gov/pubmed/29212778","Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.","Coronary artery disease","34,541 cases, 261,984 controls","88,192 cases, 162,544 controls","19q13.32","APOC1, APOC1P1","APOC1 - APOC1P1","ENSG00000130208","ENSG00000214855",null,2854,4601,"rs157595-A","rs157595",0,157595,"intergenic_variant",1,0.397,{"v":6e-06,"d":"6.00E-06"},5.22184874961635,null,0.032,"[0.018-0.046] unit decrease","Affymetrix [7947838] (imputed)","N"]
[5,"rs3832016",1,109822166,"rs599839","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","1p13.3","NR","CELSR2 - PSRC1","ENSG00000143126","ENSG00000134222",null,3794,12,"rs599839-G","rs599839",0,599839,"regulatory_region_variant",1,0.078,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.134,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs1260326",2,27742603,"rs780093","2010-09-21",20705733,"O'Seaghdha CM","2010-08-12","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/20705733","Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.","Calcium levels","20,611 European ancestry individuals","NA","2p23.3","FNDC4, IFT172, GCKR, C2orf16","GCKR",null,null,"ENSG00000084734",null,null,"rs780093-T","rs780093",0,780093,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"[NR] unit increase","Affymetrix, Illumina [~ 2500000] (imputed)","N"]
[9,"rs74175068",2,27801759,"rs1919128","2019-03-28",30718733,"Moon S","2019-02-04","Sci Rep","www.ncbi.nlm.nih.gov/pubmed/30718733","The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.","Triglyceride levels","6,949 Korean ancestry individuals","6,000 Korean ancestry individuals","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919128-G","rs1919128",0,1919128,"missense_variant",0,0.529,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0379,"[0.021-0.054] unit increase","Affymetrix [at least 805769] (imputed)","N"]
[16,"rs1235162",6,28796071,"rs3131337","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Cold sores","25,108 European ancestry cases, 63,332 European ancestry controls","NA","6p22.1","NR","NOP56P1 - AL662890.1","ENSG00000273323","ENSG00000225173",null,44290,9575,"rs3131337-?","rs3131337",0,3131337,"regulatory_region_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0811,"[0.046-0.116] unit decrease","Illumina [at least 560000] (imputed)","N"]
[16,"rs1235162",6,28916594,"rs3130844","2017-12-01",28928442,"Tian C","2017-09-19","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28928442","Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.","Urinary tract infection frequency","35,000 European ancestry cases, 33,478 European ancestry controls","NA","6p22.1","NR","LINC01556 - KRT18P1","ENSG00000231041","ENSG00000226462",null,4280,20313,"rs3130844-?","rs3130844",0,3130844,"regulatory_region_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.0564,"[0.032-0.081] unit increase","Illumina [at least 560000] (imputed)","N"]
[19,"rs55730499",6,161108144,"rs2315065","2016-12-01",27015805,"Pilling LC","2016-03-23","Aging (Albany NY)","www.ncbi.nlm.nih.gov/pubmed/27015805","Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.","Parental longevity (combined parental age at death)","45,627 middle-aged British individuals","NA","6q26","NR","AL109933.2 - AL109933.1","ENSG00000243831","ENSG00000224477",null,10589,11176,"rs2315065-?","rs2315065",0,2315065,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.056891,"[0.032-0.082] unit increase","Affymetrix [9658292] (imputed)","N"]
[21,"rs2976940",8,8304502,"rs2921077","2018-07-16",29739929,"Visconti A","2018-05-08","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/29739929","Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.","Non-melanoma skin cancer","5,912 European ancestry cases, 181,740 European ancestry controls",null,"8p23.1","NR","AC103957.1 - AC103957.2","ENSG00000253505","ENSG00000254153",null,22352,9917,"rs2921077-G","rs2921077",0,2921077,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,1.0887696,"[1.05-1.13]","Affymetrix [5734850] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.614,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.07,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs33924196",8,126507389,"rs2954038","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","8q24.13","NSMCE2, KIAA0196, TRIB1","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954038-C","rs2954038",0,2954038,"intron_variant",0,0.32,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Triglyceride, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[33,"11:47650138_AT_A",11,47529947,"rs7124681","2017-08-18",28448500,"Graff M","2017-04-27","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/28448500","Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.","Body mass index (joint analysis main effects and physical activity interaction)","2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals","6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men","11p11.2","CUGBP1","CELF1",null,null,"ENSG00000149187",null,null,"rs7124681-?","rs7124681",0,7124681,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(men)",null,null,"Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)","N"]
[35,"rs473172",11,116921397,"rs1815787","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Subjective well-being","298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","11q23.3","NR","SIK3",null,null,"ENSG00000160584",null,null,"rs1815787-T","rs1815787",0,1815787,"intron_variant",0,0.1173,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.020935446,"[0.012-0.03] unit increase","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[37,"rs4766578",12,111833788,"rs10774624","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma-induced protein 10 levels","3,685 Finnish ancestry individuals","NA","12q24.12","NR","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-G","rs10774624",0,10774624,"intron_variant",0,null,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.1069,"[0.06-0.154] SD units increase","NR [10700000] (imputed)","N"]
[41,"rs261290",15,58683366,"rs1532085","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.376,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Hispanic)",0.057,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[41,"rs13329672",15,58699937,"rs13329672","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs13329672-C","rs13329672",0,13329672,"intron_variant",0,0.815,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(East Asian)",0.077,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[47,"rs11662596",18,47121316,"rs17798991","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","18q21.1","LIPG","LIPG",null,null,"ENSG00000101670",null,null,"rs17798991-A","rs17798991",0,17798991,"3_prime_UTR_variant",0,0.387,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(Light activity )",0.03,"[NR] %awake time increase","Illumina [899892]","N"]
[47,"rs7239952",18,47280410,"rs9964067","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","18q21.1","NR","AC090227.2 - ACAA2","ENSG00000267674","ENSG00000167315",null,11977,28127,"rs9964067-T","rs9964067",0,9964067,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.02,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs737337",19,11347493,"rs737337","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs737337-T","rs737337",0,737337,"synonymous_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.032,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[54,"rs1883711",20,39142516,"rs2207132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,387519,171972,"rs2207132-G","rs2207132",0,2207132,"intergenic_variant",1,0.963,{"v":7e-06,"d":"7.00E-06"},5.15490195998574,"(EA)",0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[54,"rs1883711",20,39142516,"rs2207132","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q12","NR","AL009050.1 - MAFB","ENSG00000223410","ENSG00000204103",null,387519,171972,"rs2207132-G","rs2207132",0,2207132,"intergenic_variant",1,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,null,0.05,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21928641,"rs181359","2018-09-20",30019117,"Liu J","2018-07-17","Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30019117","The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.","Adolescent idiopathic scoliosis","196 cases, 303 controls","NA","22q11.21","NR","UBE2L3",null,null,"ENSG00000185651",null,null,"rs181359-?","rs181359",0,181359,"intron_variant",0,"NR",{"v":7e-06,"d":"7.00E-06"},5.15490195998574,{"$nulls":3},"Affymetrix [NR]","N"]
[4,"1:62980399_CACA_C",1,63118196,"rs10889353","2009-01-12",19060911,"Aulchenko YS","2008-12-07","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/19060911","Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.","LDL cholesterol","17,083 European ancestry individuals, 714 Orcadian individuals","NA","1p31.3","DOCK7","DOCK7",null,null,"ENSG00000116641",null,null,"rs10889353-C","rs10889353",0,10889353,"intron_variant",0,0.32,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.06,"[NR] s.d. decrease","Affymetrix, Illumina [up to 600000]","N"]
[8,"rs668948",2,21294975,"rs541041","2010-04-14",20339536,"Barber MJ","2010-03-22","PLoS One","www.ncbi.nlm.nih.gov/pubmed/20339536","Genome-wide association of lipid-lowering response to statins in combined study populations.","Response to statin therapy","3,928 European ancestry individuals","NA","2p24.1","FLJ21820, GDF7, APOB","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,28030,51814,"rs541041-G","rs541041",0,541041,"intergenic_variant",1,0.16,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(LDL, sum)",null,null,"Illumina [~ 2500000] (imputed)","N"]
[21,"rs2126259",8,9184231,"rs4240624","2016-07-23",26198764,"Goes FS","2015-07-21","Am J Med Genet B Neuropsychiatr Genet","www.ncbi.nlm.nih.gov/pubmed/26198764","Genome-wide association study of schizophrenia in Ashkenazi Jews.","Schizophrenia","592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4240624-G","rs4240624",0,4240624,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.0869565,"[NR]","Illumina [7158791] (imputed)","N"]
[21,"rs4240623",8,9186524,"rs4841134","2017-05-15",27790247,"He L","2016-11-03","Front Genet","www.ncbi.nlm.nih.gov/pubmed/27790247","Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.","Age-related disease endophenotypes","9,618 European ancestry individuals","19,796 European ancestry individuals","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs4841134-?","rs4841134",0,4841134,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,{"$nulls":3},"Affymetrix [NR]","N"]
[21,"rs7005363",8,10283426,"rs3750310","2018-06-29",28714469,"Langefeld CD","2017-07-17","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/28714469","Transancestral mapping and genetic load in systemic lupus erythematosus.","Systemic lupus erythematosus","6,748 European ancestry cases, 11,516 European ancestry controls, 2,970 African American cases, 2,452 African American controls, 1,872 Hispanic cases, 2,016 Hispanic controls","NA","8p23.1","MSRA","MSRA",null,null,"ENSG00000175806",null,null,"rs3750310-G","rs3750310",0,3750310,"intron_variant",0,0.692,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(Hispanic)",1.28,"[1.15-1.42]","Illumina [at least 5000000] (imputed)","N"]
[22,"rs11250098",8,11039816,"rs2409722","2017-03-17",27089181,"Okbay A","2016-04-18","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27089181","Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.","Positive affect","180,281 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals","NA","8p23.1","NR","XKR6",null,null,"ENSG00000171044",null,null,"rs2409722-T","rs2409722",0,2409722,"intron_variant",0,0.488,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.0149,"[0.0084-0.0214] unit increase","Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126482621,"rs2954022","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954022-C","rs2954022",0,2954022,"intron_variant",0,0.486,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126491733,"rs2954031","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2954031-G","rs2954031",0,2954031,"intron_variant",0,0.502,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.072,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs112875651",8,126506694,"rs112875651","2019-02-10",27841878,"Hoffmann TJ","2016-11-14","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27841878","Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.","Diastolic blood pressure","295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals","NA","8q24.13","TRIB1, LOC100130231","AC091114.1",null,null,"ENSG00000253111",null,null,"rs112875651-G","rs112875651",0,112875651,"intron_variant",0,null,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,0.11,"unit increase","Affymetrix [at least 2696785] (imputed)","N"]
[29,"rs4149307",9,107591272,"rs7031748","2013-01-16",23049088,"Meng W","2012-10-09","Invest Ophthalmol Vis Sci","www.ncbi.nlm.nih.gov/pubmed/23049088","A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.","Myopia (pathological)","187 European ancestry cases, 1064 European ancestry controls",null,"9q31.1","intergenic","ABCA1",null,null,"ENSG00000165029",null,null,"rs7031748-?","rs7031748",1,2853579,"synonymous_variant",0,0.134,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,null,"[NR]","Affymetrix, Illumina [152234]","N"]
[29,"rs62568184",9,107657070,"rs3905000","2017-08-07",27082954,"Ward-Caviness CK","2016-04-15","PLoS One","www.ncbi.nlm.nih.gov/pubmed/27082954","Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease.","Peripheral arterial disease (traffic-related air pollution interaction)","104 European ancestry cases, 1,519 European ancestry controls, 34 African American cases, 520 African American controls","NA","9q31.1","NR","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-?","rs3905000",0,3905000,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(AA)",5,"[4.14-5.86]","Illumina [905956]","N"]
[31,"rs117488242",10,5254847,"rs1832007","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","10p15.1","NR","AKR1C4",null,null,"ENSG00000198610",null,null,"rs1832007-A","rs1832007",0,1832007,"intron_variant",0,0.852,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA)",0.026,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[35,"rs11820589",11,116613660,"rs12280753","2010-09-28",20838585,"Smith EN","2010-09-09","PLoS Genet","www.ncbi.nlm.nih.gov/pubmed/20838585","Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.","Cardiovascular risk factors (age interaction)","525 European ancestry individuals","2,442 Finnish ancestry individuals","11q23.3","CADM1, APOA5, BUD13","AP000770.1 - BUD13","ENSG00000237937","ENSG00000137656",null,84692,5226,"rs12280753-T","rs12280753",0,12280753,"regulatory_region_variant",1,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(triglycerides)",0.69,"[0.40-0.98] unit increase","Illumina [2173391] (imputed)","N"]
[37,"rs4766578",12,111904371,"rs4766578","2018-04-25",24097067,"Lessard CJ","2013-11-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097067","Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.","Sjögren's syndrome","1,541 European ancestry cases, 2,634 European ancestry controls","NA","12q24.12","ATXN2","ATXN2",null,null,"ENSG00000204842",null,null,"rs4766578-T","rs4766578",0,4766578,"intron_variant",0,0.48,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.23,"[1.12-1.35]","Illumina [102585]","N"]
[41,"rs261290",15,58683366,"rs1532085","2018-09-20",29404214,"Andaleon A","2018-01-29","PeerJ","www.ncbi.nlm.nih.gov/pubmed/29404214","Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.","HDL cholesterol","1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals","NA","15q21.3","LIPC","ALDH1A2",null,null,"ENSG00000128918",null,null,"rs1532085-A","rs1532085",0,1532085,"intron_variant",0,0.403,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(Filipino)",1.634,"[1.56-1.70] unit decrease","Affymetrix, Illumina [up to 12553142] (imputed)","N"]
[41,"rs1077835",15,58726744,"rs261334","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","15q21.3","NR","LIPC, ALDH1A2",null,null,"ENSG00000166035, ENSG00000128918",null,null,"rs261334-G","rs261334",0,261334,"intron_variant",0,0.358,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(East Asian)",0.068,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[48,"rs56322906",19,11330942,"rs17699030","2012-11-02",20889312,"Wang KS","2010-10-01","Schizophr Res","www.ncbi.nlm.nih.gov/pubmed/20889312","A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.","Bipolar disorder and schizophrenia","651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls","NA","19p13.2","NR","DOCK6",null,null,"ENSG00000130158",null,null,"rs17699030-?","rs17699030",0,17699030,"intron_variant",0,"NR",{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7062,"[NR]","Affymetrix [722112]","N"]
[49,"19:19756073_AGCC_A",19,19789528,"rs2304130","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19p13.11","NR","ZNF101",null,null,"ENSG00000181896",null,null,"rs2304130-A","rs2304130",0,2304130,"splice_region_variant",0,0.921,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(EA)",0.04,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs184017",19,45392254,"rs6857","2016-04-28",26154020,"Ferrari R","2015-06-12","Neurobiol Aging","www.ncbi.nlm.nih.gov/pubmed/26154020","A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.","Frontotemporal dementia","530 European ancestry cases, 926 European ancestry controls","NA","19q13.32","PVRL2","AC011481.2, NECTIN2",null,null,"ENSG00000267114, ENSG00000130202",null,null,"rs6857-T","rs6857",0,6857,"3_prime_UTR_variant",0,0.13,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,null,1.7,"[1.46-1.94]","Illumina [2292247] (imputed)","N"]
[56,"rs1800961",20,43042364,"rs1800961","2012-11-02",22939635,"Reiner AP","2012-08-28","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/22939635","Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.","C-reactive protein","8,280 African American female individuals, 3,548 Hispanic female individuals","3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals","20q13.12","HNF4A","HNF4A",null,null,"ENSG00000101076",null,null,"rs1800961-T","rs1800961",0,1800961,"missense_variant",0,0.04,{"v":8e-06,"d":"8.00E-06"},5.09691001300805,"(HA women)",0.268,"[0.15-0.39] unit decrease","Affymetrix [up to 2203609] (imputed)","N"]
[3,"rs11591147",1,55505647,"rs11591147","2018-05-11",29436472,"Casalone E","2018-02-07","Ann Rheum Dis","www.ncbi.nlm.nih.gov/pubmed/29436472","A novel variant in GLIS3 is associated with osteoarthritis.","Osteoarthritis of the knee (with total joint replacement)","2,188 European ancestry cases, 9,939 European ancestry healthy controls","2,281 European ancestry cases, 9,194 European ancestry healthy controls","1p32.3","NR","PCSK9",null,null,"ENSG00000169174",null,null,"rs11591147-T","rs11591147",0,11591147,"missense_variant",0,0.017137,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,1.56,"[1.25-1.95]","Illumina [270934]","N"]
[4,"1:62980399_CACA_C",1,62912919,"rs10158897","2014-08-02",24386095,"Zhou L","2013-12-30","PLoS One","www.ncbi.nlm.nih.gov/pubmed/24386095","A genome wide association study identifies common variants associated with lipid levels in the Chinese population.","Lipid traits","3,451 Han Chinese ancestry individuals","8,830 Han Chinese ancestry individuals","1p31.3","USP1","USP1",null,null,"ENSG00000162607",null,null,"rs10158897-T","rs10158897",0,10158897,"intron_variant",0,0.2,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(LDL)",0.021,"mmol/L decrease","Affymetrix, Illumina [up to 2249917] (imputed)","N"]
[8,"rs668948",2,21286057,"rs515135","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","2p24.1","NR","APOB - TDRD15","ENSG00000084674","ENSG00000218819",null,19112,60732,"rs515135-T","rs515135",0,515135,"intergenic_variant",1,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.021,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[9,"rs67798437",2,27801418,"rs1919126","2018-09-07",27618448,"Liu C","2016-10-01","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/27618448","Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.","Mean arterial pressure","120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals","NA","2p23.3","C2orf16","C2orf16",null,null,"ENSG00000221843",null,null,"rs1919126-C","rs1919126",0,1919126,"missense_variant",0,null,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.20432469,"[0.11-0.29] unit decrease","Illumina [247039]","N"]
[10,"rs11887534",2,44066247,"rs11887534","2019-03-21",30325047,"Gellert-Kristensen H","2018-10-16","Hepatology","www.ncbi.nlm.nih.gov/pubmed/30325047","Identification and replication of six new loci associated with gallstone disease.","Gallstone disease","14,940 British ancestry cases, 322,268 British ancestry controls","1,522 Danish ancestry cases, 18,266 Danish ancestry controls","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-C","rs11887534",0,11887534,"missense_variant",0,0.07,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,2.01,"[1.94-2.08]","Affymetrix [784257]","N"]
[17,"rs59136961",6,34552797,"rs2814944","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","6p21.31","NR","AL031577.1 - C6orf106","ENSG00000196114","ENSG00000196821",null,8364,2268,"rs2814944-G","rs2814944",0,2814944,"intergenic_variant",1,0.844,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.028,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[21,"rs2126259",8,9181395,"rs2169387","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8p23.1","NR","AC022784.1",null,null,"ENSG00000248538",null,null,"rs2169387-A","rs2169387",0,2169387,"intron_variant",0,0.096,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.031,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.071,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[26,"rs2954021",8,126481747,"rs2980875","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Triglycerides","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","8q24.13","NR","AC091114.1",null,null,"ENSG00000253111",null,null,"rs2980875-A","rs2980875",0,2980875,"intron_variant",0,0.486,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.065,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[29,"rs4149307",9,107588777,"rs4149311","2013-01-16",23049088,"Meng W","2012-10-09","Invest Ophthalmol Vis Sci","www.ncbi.nlm.nih.gov/pubmed/23049088","A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.","Myopia (pathological)","187 European ancestry cases, 1064 European ancestry controls",null,"9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs4149311-?","rs4149311",0,4149311,"intron_variant",0,0.134,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,null,"[NR]","Affymetrix, Illumina [152234]","N"]
[29,"rs62568184",9,107657070,"rs3905000","2016-03-24",21116278,"Furney SJ","2010-11-30","Mol Psychiatry","www.ncbi.nlm.nih.gov/pubmed/21116278","Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.","Whole-brain volume (Alzheimer's disease interaction)","434 European ancestry mild cognitive impairment cases, 245 European ancestry Alzheimer's disease cases, 284 European ancestry controls","NA","9q31.1","ABCA1","ABCA1",null,null,"ENSG00000165029",null,null,"rs3905000-?","rs3905000",0,3905000,"intron_variant",0,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.013,"[NR] unit increase","Illumina [478011]","N"]
[35,"rs2072560",11,116647607,"rs2160669","2013-04-09",23251661,"Comuzzie AG","2012-12-04","PLoS One","www.ncbi.nlm.nih.gov/pubmed/23251661","Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.","Obesity-related traits","815 Hispanic children from 263 families","NA","11q23.3","ZNF259, APOA5","ZPR1",null,null,"ENSG00000109917",null,null,"rs2160669-G","rs2160669",0,2160669,"3_prime_UTR_variant",0,0.168,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(TG/HDLC )",0.03,"[NR] mmol/L increase","Illumina [899892]","N"]
[35,"rs2072560",11,116660686,"rs2266788","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Total cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","11q23.3","NR","APOA5",null,null,"ENSG00000110243",null,null,"rs2266788-G","rs2266788",0,2266788,"3_prime_UTR_variant",0,0.115,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(Hispanic)",0.104,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[37,"rs4766578",12,111833788,"rs10774624","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Monokine induced by gamma interferon levels","3,685 Finnish ancestry individuals","NA","12q24.12","NR","LINC02356",null,null,"ENSG00000257595",null,null,"rs10774624-G","rs10774624",0,10774624,"intron_variant",0,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.1056,"[0.059-0.152] SD units increase","NR [10700000] (imputed)","N"]
[37,"rs11066320",12,112817521,"rs10850034","2017-08-04",27989323,"Ahola-Olli AV","2016-12-13","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/27989323","Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.","Interferon gamma-induced protein 10 levels","3,685 Finnish ancestry individuals","NA","12q24.13","NR","HECTD4",null,null,"ENSG00000173064",null,null,"rs10850034-T","rs10850034",0,10850034,"intron_variant",0,null,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,null,0.1055,"[0.059-0.152] SD units decrease","NR [10700000] (imputed)","N"]
[42,"rs289713",16,57006590,"rs7499892","2009-03-31",19260141,"Zemunik T","2009-02-01","Croat Med J","www.ncbi.nlm.nih.gov/pubmed/19260141","Genome-wide association study of biochemical traits in Korcula Island, Croatia.","Biochemical measures","898 Korculan (founder/genetic isolate) individuals","NA","16q13","CETP","CETP",null,null,"ENSG00000087237",null,null,"rs7499892-A","rs7499892",0,7499892,"intron_variant",0,0.16,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(HDL cholesterol)",0.24,"[0.14-0.34] mmol/L decrease","Illumina [316730]","N"]
[50,"19:45311297_AGCTTG_A",19,45296806,"rs3208856","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","High density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","CBLC",null,null,"ENSG00000142273",null,null,"rs3208856-C","rs3208856",0,3208856,"missense_variant",0,0.964,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.045,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[50,"rs75627662",19,45416741,"rs438811","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","19q13.32","NR","AC011481.3",null,null,"ENSG00000267282",null,null,"rs438811-C","rs438811",0,438811,"non_coding_transcript_exon_variant",0,0.883,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(East Asian)",0.123,"unit decrease","Affymetrix [at least 7091467] (imputed)","N"]
[53,"rs2378390",20,34125271,"rs6579245","2019-02-14",29507422,"Hoffmann TJ","2018-03-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29507422","A large electronic-health-record-based genome-wide study of serum lipids.","Low density lipoprotein cholesterol levels","76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals","NA","20q11.22","NR","C20orf173 - ERGIC3","ENSG00000125975","ENSG00000125991",null,7795,4574,"rs6579245-C","rs6579245",0,6579245,"intergenic_variant",1,0.85,{"v":9e-06,"d":"9.00E-06"},5.04575749056067,"(EA)",0.029,"unit increase","Affymetrix [at least 7091467] (imputed)","N"]
[57,"rs5754102",22,21922904,"rs2266959","2017-06-02",28067908,"de Lange KM","2017-01-09","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/28067908","Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.","Ulcerative colitis","12,366 European and unknown ancestry cases, 33,609 European and unknown ancestry controls","NA","22q11.21","YDJC, SDF2L1, UBE2L3, CCDC116","UBE2L3",null,null,"ENSG00000185651",null,null,"rs2266959-?","rs2266959",0,2266959,"intron_variant",0,"NR",{"v":9e-06,"d":"9.00E-06"},5.04575749056067,{"$nulls":3},"Illumina [9578670] (imputed)","N"]
[38,"rs7970695",12,121423659,"rs9738226","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","12q24.31","HNF1A","HNF1A",null,null,"ENSG00000135100",null,null,"rs9738226-A","rs9738226",0,9738226,"intron_variant",0,0.39,"1E-313",313,"(BMI-adjusted)",0.148,"[0.14-0.16] unit decrease","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[10,"rs11887534",2,44066247,"rs11887534","2019-02-21",30504769,"Ferkingstad E","2018-11-30","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30504769","Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.","Gallstone disease","27,174 European ancestry cases, 736,838 European ancestry controls","NA","2p21","ABCG8","ABCG8",null,null,"ENSG00000143921",null,null,"rs11887534-?","rs11887534",0,11887534,"missense_variant",0,null,"1E-353",353,null,1.94,"[1.88-2.08]","Affymetrix, Illumina [43000000] (imputed)","N"]
[19,"rs55730499",6,160985526,"rs118039278","2017-08-01",28512139,"Mack S","2017-05-16","J Lipid Res","www.ncbi.nlm.nih.gov/pubmed/28512139","A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.","Lipoprotein (a) levels","13,781 European ancestry individuals","NA","6q25.3","LPA","LPA",null,null,"ENSG00000198670",null,null,"rs118039278-A","rs118039278",0,118039278,"intron_variant",0,null,"1E-396",396,null,32.43,"[31.14-33.72] mg/dL increase","Affymetrix, Illumina [at least 7600000] (imputed)","N"]
[35,"rs964184",11,116648917,"rs964184","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","Triglycerides x physical activity interaction (2df test)","7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals","580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals","11q23.3","NR","ZPR1",null,null,"ENSG00000109917",null,null,"rs964184-C","rs964184",0,964184,"3_prime_UTR_variant",0,0.8418,"1E-500",500,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[42,"rs3764261",16,56985514,"rs72786786","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","HDL cholesterol x physical activity interaction (2df test)","7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals","1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals","16q13","NR","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,6739,10248,"rs72786786-A","rs72786786",0,72786786,"regulatory_region_variant",1,0.3106,"1E-500",500,"(EA)",null,null,"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[50,"rs41290120",19,45382675,"rs41290120","2019-03-12",30670697,"Kilpelainen TO","2019-01-22","Nat Commun","www.ncbi.nlm.nih.gov/pubmed/30670697","Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.","LDL cholesterol x physical activity interaction (2df test)","7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals","571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals,  724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals,  33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals","19q13.32","NR","NECTIN2",null,null,"ENSG00000130202",null,null,"rs41290120-A","rs41290120",0,41290120,"intron_variant",0,0.0416,"1E-500",500,{"$nulls":3},"Affymetrix, Illumina [at least 2500000] (imputed)","N"]
[35,"rs2072560",11,116662579,"rs651821","2018-07-28",29403010,"Kanai M","2018-02-05","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/29403010","Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.","Triglyceride levels","105,597 Japanese ancestry individuals","NA","11q23.3","APOA5","APOA5",null,null,"ENSG00000110243",null,null,"rs651821-?","rs651821",0,651821,"5_prime_UTR_variant",0,"NR","1E-537",537,null,0.2208,"[0.21-0.23] unit decrease novel","Illumina [6108953] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2014-05-12",24097068,"Willer CJ","2013-10-06","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/24097068","Discovery and refinement of loci associated with lipid levels.","HDL cholesterol","94,595 European ancestry individuals","93,982 European ancestry individuals","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,"1E-769",769,null,0.241,"[NR] unit increase","NR [NR] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,"3E-418",417.52287874528,"(Leucine-rich repeat neuronal protein 1, LRRN1.11293.14.3)",1.18,"[1.12-1.24] unit increase","Affymetrix [10572788] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.078,"3E-484",483.52287874528,"(Vacuolar protein sorting-associated protein 29, VPS29.14318.1.3)",1.69,"[1.61-1.77] unit increase","Affymetrix [10572788] (imputed)","N"]
[35,"rs2072560",11,116663707,"rs662799","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Triglyceride levels","28,183 East Asian ancestry individuals, 177,861 European ancestry individuals","10,857 Chinese ancestry individuals","11q23.3","APOA1, APOC3, APOA4, APOA5","APOA5 - AP006216.2","ENSG00000110243","ENSG00000236267",null,571,20213,"rs662799-A","rs662799",0,662799,"intergenic_variant",1,0.92,"4E-315",314.397940008672,"(Trans-ethnic initial)",0.247,"[0.23-0.26] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE, APOC1","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,"4E-328",327.397940008672,null,0.247,"[0.24-0.26] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[50,"rs1065853",19,45413233,"rs1065853","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","LDL cholesterol","up 62,166 European ancestry individuals","NA","19q13.32","APOE","AC011481.3",null,null,"ENSG00000267282",null,null,"rs1065853-G","rs1065853",0,1065853,"non_coding_transcript_exon_variant",0,0.93,"5E-324",323.301029995663,null,0.603,"[0.58-0.63] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-C","rs429358",0,429358,"missense_variant",0,0.153,"5E-646",645.301029995664,"(Tubulin-specific chaperone A, TBCA.12501.10.3)",1.34,"[1.3-1.38] unit decrease","Affymetrix [10572788] (imputed)","N"]
[50,"rs429358",19,45411941,"rs429358","2019-04-18",30388399,"Ligthart S","2018-11-01","Am J Hum Genet","www.ncbi.nlm.nih.gov/pubmed/30388399","Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.","C-reactive protein levels","148,164 European ancestry individuals","NA","19q13.32","APOE","APOE",null,null,"ENSG00000130203",null,null,"rs429358-T","rs429358",0,429358,"missense_variant",0,0.85,"6E-363",362.221848749616,"(BMI-adjusted)",0.24,"[0.23-0.25] unit increase","Affymetrix, Illumina, Perlegen [10019203] (imputed)","N"]
[42,"rs3764261",16,56994528,"rs17231506","2016-07-08",25961943,"Surakka I","2015-05-11","Nat Genet","www.ncbi.nlm.nih.gov/pubmed/25961943","The impact of low-frequency and rare variants on lipid levels.","HDL cholesterol","up to 62,166 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,15753,1234,"rs17231506-T","rs17231506",0,17231506,"regulatory_region_variant",1,0.31,"7E-316",315.154901959985,null,0.243,"[0.23-0.25] s.d. increase","Affymetrix, Illumina, Perlegen [up to 9657952] (imputed)","N"]
[50,"rs111606839",19,45448465,"rs5167","2018-07-05",29875488,"Sun BB","2018-06-06","Nature","www.ncbi.nlm.nih.gov/pubmed/29875488","Genomic atlas of the human plasma proteome.","Blood protein levels","3,301 European ancestry individuals","NA","19q13.32","APOC4","APOC4, APOC4-APOC2",null,null,"ENSG00000267467, ENSG00000224916",null,null,"rs5167-G","rs5167",0,5167,"missense_variant",0,0.347,"7E-370",369.154901959985,"(Valine--tRNA ligase, VARS.13083.18.3)",0.87,"[0.83-0.91] unit increase","Affymetrix [10572788] (imputed)","N"]
[42,"rs3764261",16,56993324,"rs3764261","2012-01-25",20686565,"Teslovich TM","2010-08-05","Nature","www.ncbi.nlm.nih.gov/pubmed/20686565","Biological, clinical and population relevance of 95 loci for blood lipids.","HDL cholesterol","99,900 European ancestry individuals","NA","16q13","CETP","HERPUD1 - CETP","ENSG00000051108","ENSG00000087237",null,14548,2511,"rs3764261-A","rs3764261",0,3764261,"regulatory_region_variant",1,0.32,"7E-380",379.154901959985,null,3.39,"[3.21-3.57] mg/dL increase","Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)","N"]
[50,"rs1065853",19,45412079,"rs7412","2017-06-26",28334899,"Spracklen CN","2017-02-21","Hum Mol Genet","www.ncbi.nlm.nih.gov/pubmed/28334899","Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.","Total cholesterol levels","32,576 East Asian ancestry individuals, 187,365 European ancestry individuals","10,855 Chinese ancestry individuals","19q13.32","APOE, APOC1, APOC2","APOE",null,null,"ENSG00000130203",null,null,"rs7412-T","rs7412",0,7412,"missense_variant",0,0.066,"8E-315",314.096910013008,"(Trans-ethnic initial)",0.374,"[0.36-0.39] unit decrease (EA Beta values)","Affymetrix, Illumina [up to 1900000] (imputed)","N"]
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["LA","MVMR (+ApoB)",{"v":111.9034136002695,"d":"112"},{"v":152.8741734651883,"d":"153"},{"v":2.7218495761815611E-8,"d":"3E-08"},72,"Aortic valve stenosis","UKB"]
["LA","MVMR (+Clinical_LDL_C)",{"v":125.5535261598615,"d":"126"},{"v":159.6601286868754,"d":"160"},{"v":2.446928475933852E-9,"d":"2E-09"},71,"Aortic valve stenosis","UKB"]
["LA","MVMR (+Total_FA)",{"v":57.2890359714306,"d":"57"},{"v":152.3063665048699,"d":"152"},{"v":8.93458441036872e-09,"d":"9E-09"},69,"Aortic valve stenosis","UKB"]
["LA","MVMR (+Total_TG)",{"v":58.50041563008892,"d":"59"},{"v":190.8426268133401,"d":"191"},{"v":4.184664971123562e-10,"d":"4E-10"},88,"Aortic valve stenosis","UKB"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.00515943461719,"d":"52"},{"v":185.4873343753628,"d":"185"},{"v":8.29414421010845e-08,"d":"8E-08"},99,"Aortic valve stenosis","UKB"]
["LA","MVMR (+ApoB)",{"v":115.9700548754255,"d":"116"},{"v":149.9819538459917,"d":"150"},{"v":1.76461067005033E-8,"d":"2E-08"},69,"Atrial fibrillation","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":128.1195780884162,"d":"128"},{"v":140.3761998826771,"d":"140"},{"v":2.714114816877395E-7,"d":"3E-07"},69,"Atrial fibrillation","Pooled"]
["LA","MVMR (+Total_FA)",{"v":58.75391075227839,"d":"59"},{"v":183.7105742757401,"d":"184"},{"v":1.676149837239322E-13,"d":"2E-13"},67,"Atrial fibrillation","Pooled"]
["LA","MVMR (+Total_TG)",{"v":59.4432812341679,"d":"59"},{"v":265.9383392106236,"d":"266"},{"v":5.048778641429403e-21,"d":"5E-21"},86,"Atrial fibrillation","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.79948979631416,"d":"53"},{"v":278.5751900343467,"d":"279"},{"v":2.07857061807799e-20,"d":"2E-20"},97,"Atrial fibrillation","Pooled"]
["LA","MVMR (+ApoB)",{"v":111.9034136002695,"d":"112"},{"v":919.8903138191525,"d":"920"},{"v":6.010959425772439e-149,"d":"6E-149"},72,"Coronary artery disease","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":125.5535261598615,"d":"126"},{"v":1003.937761615348,"d":"1004"},{"v":1.624805590919963e-166,"d":"2E-166"},71,"Coronary artery disease","Pooled"]
["LA","MVMR (+Total_FA)",{"v":57.2890359714306,"d":"57"},{"v":1339.171273923444,"d":"1339"},{"v":1.696331097513219e-236,"d":"2E-236"},69,"Coronary artery disease","Pooled"]
["LA","MVMR (+Total_TG)",{"v":58.50041563008892,"d":"59"},{"v":1504.946896175552,"d":"1505"},{"v":1.858484214406426e-258,"d":"2E-258"},88,"Coronary artery disease","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.00515943461719,"d":"52"},{"v":1094.864767595305,"d":"1095"},{"v":1.11817994080356E-169,"d":"1E-169"},99,"Coronary artery disease","Pooled"]
["LA","MVMR (+ApoB)",{"v":115.9209896727752,"d":"116"},{"v":201.7523094170391,"d":"202"},{"v":1.132448860076047e-15,"d":"1E-15"},69,"Heart failure","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":128.1051129744469,"d":"128"},{"v":206.2545388116117,"d":"206"},{"v":2.392652820834291e-16,"d":"2E-16"},69,"Heart failure","Pooled"]
["LA","MVMR (+Total_FA)",{"v":58.77609558303334,"d":"59"},{"v":210.2811002872593,"d":"210"},{"v":1.767072982568371e-17,"d":"2E-17"},67,"Heart failure","Pooled"]
["LA","MVMR (+Total_TG)",{"v":59.35912868536345,"d":"59"},{"v":270.0416823196636,"d":"270"},{"v":1.198612391727612e-21,"d":"1E-21"},86,"Heart failure","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.82969467222846,"d":"53"},{"v":252.7015792937625,"d":"253"},{"v":1.074794792908471E-16,"d":"1E-16"},97,"Heart failure","Pooled"]
["LA","MVMR (+ApoB)",{"v":111.9034136002695,"d":"112"},{"v":82.95161325169148,"d":"83"},{"v":0.1206436922249515,"d":"1E-01"},72,"Hemorrhagic stroke","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":125.5535261598615,"d":"126"},{"v":78.17496054957695,"d":"78"},{"v":0.1870155474598848,"d":"2E-01"},71,"Hemorrhagic stroke","Pooled"]
["LA","MVMR (+Total_FA)",{"v":57.2890359714306,"d":"57"},{"v":77.47541084617939,"d":"77"},{"v":0.1578257006841919,"d":"2E-01"},69,"Hemorrhagic stroke","Pooled"]
["LA","MVMR (+Total_TG)",{"v":58.50041563008892,"d":"59"},{"v":94.02213266232071,"d":"94"},{"v":0.2358799165538245,"d":"2E-01"},88,"Hemorrhagic stroke","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.00515943461719,"d":"52"},{"v":102.0488130054818,"d":"102"},{"v":0.2920707625426366,"d":"3E-01"},99,"Hemorrhagic stroke","Pooled"]
["LA","MVMR (+ApoB)",{"v":111.9034136002695,"d":"112"},{"v":172.0826126631479,"d":"172"},{"v":8.950571379365385e-11,"d":"9E-11"},72,"Ischemic stroke","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":125.5535261598615,"d":"126"},{"v":185.3893380542156,"d":"185"},{"v":8.028670830072409e-13,"d":"8E-13"},71,"Ischemic stroke","Pooled"]
["LA","MVMR (+Total_FA)",{"v":57.2890359714306,"d":"57"},{"v":197.4863082851879,"d":"197"},{"v":4.87039489860297e-15,"d":"5E-15"},69,"Ischemic stroke","Pooled"]
["LA","MVMR (+Total_TG)",{"v":58.50041563008892,"d":"59"},{"v":235.7182470330197,"d":"236"},{"v":4.234312246236014e-16,"d":"4E-16"},88,"Ischemic stroke","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.00515943461719,"d":"52"},{"v":223.5908410489878,"d":"224"},{"v":2.255138590234801e-12,"d":"2E-12"},99,"Ischemic stroke","Pooled"]
["LA","MVMR (+ApoB)",{"v":111.9034136002695,"d":"112"},{"v":211.5305455202976,"d":"212"},{"v":2.19852723294422E-16,"d":"2E-16"},72,"Peripheral artery disease","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":125.5535261598615,"d":"126"},{"v":233.321823700754,"d":"233"},{"v":5.585799039701333e-20,"d":"6E-20"},71,"Peripheral artery disease","Pooled"]
["LA","MVMR (+Total_FA)",{"v":57.2890359714306,"d":"57"},{"v":203.7359387547492,"d":"204"},{"v":5.719629545423817e-16,"d":"6E-16"},69,"Peripheral artery disease","Pooled"]
["LA","MVMR (+Total_TG)",{"v":58.50041563008892,"d":"59"},{"v":259.9806925821773,"d":"260"},{"v":1.268384548623524E-19,"d":"1E-19"},88,"Peripheral artery disease","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.00515943461719,"d":"52"},{"v":241.3938201422469,"d":"241"},{"v":1.030885869580623E-14,"d":"1E-14"},99,"Peripheral artery disease","Pooled"]
["LA","MVMR (+ApoB)",{"v":111.9034136002695,"d":"112"},{"v":913.8715715849761,"d":"914"},{"v":9.786249030140758e-148,"d":"1E-147"},72,"Venous thromboembolism","Pooled"]
["LA","MVMR (+Clinical_LDL_C)",{"v":125.5535261598615,"d":"126"},{"v":898.5345913960996,"d":"899"},{"v":3.256234754300186e-145,"d":"3E-145"},71,"Venous thromboembolism","Pooled"]
["LA","MVMR (+Total_FA)",{"v":57.2890359714306,"d":"57"},{"v":943.2965965383112,"d":"943"},{"v":2.146846256754387e-155,"d":"2E-155"},69,"Venous thromboembolism","Pooled"]
["LA","MVMR (+Total_TG)",{"v":58.50041563008892,"d":"59"},{"v":939.4301547923704,"d":"939"},{"v":3.906423412513729e-144,"d":"4E-144"},88,"Venous thromboembolism","Pooled"]
["LA","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.00515943461719,"d":"52"},{"v":953.1987170763213,"d":"953"},{"v":1.043942434997837e-141,"d":"1E-141"},99,"Venous thromboembolism","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":149.7532258711796,"d":"150"},{"v":6.6453038090817383E-7,"d":"7E-07"},78,"Aortic aneurysm","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":151.6503084215828,"d":"152"},{"v":1.8951673051863731E-7,"d":"2E-07"},76,"Aortic aneurysm","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":177.8996415353699,"d":"178"},{"v":3.826800578173356e-11,"d":"4E-11"},74,"Aortic aneurysm","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":224.9351703425298,"d":"225"},{"v":3.66434713346548e-14,"d":"4E-14"},90,"Aortic aneurysm","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":239.9716638416925,"d":"240"},{"v":3.927759961930176e-13,"d":"4E-13"},106,"Aortic aneurysm","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":259.3752754529221,"d":"259"},{"v":3.861661269555042e-22,"d":"4E-22"},78,"Aortic valve stenosis","UKB"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":252.1498433614486,"d":"252"},{"v":1.477748105192592e-21,"d":"1E-21"},76,"Aortic valve stenosis","UKB"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":252.5570246156339,"d":"253"},{"v":3.548308283393093E-22,"d":"4E-22"},74,"Aortic valve stenosis","UKB"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":302.5262501539253,"d":"303"},{"v":1.331977331848334e-25,"d":"1E-25"},90,"Aortic valve stenosis","UKB"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":310.36511369261,"d":"310"},{"v":6.778525100118836e-23,"d":"7E-23"},106,"Aortic valve stenosis","UKB"]
["Omega_3","MVMR (+ApoB)",{"v":83.24226798944612,"d":"83"},{"v":285.6392450446232,"d":"286"},{"v":1.261409715016723e-26,"d":"1E-26"},77,"Atrial fibrillation","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":267.9170528170307,"d":"268"},{"v":4.691312493416447e-24,"d":"5E-24"},76,"Atrial fibrillation","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":292.7578765557643,"d":"293"},{"v":1.028869707104277e-28,"d":"1E-28"},74,"Atrial fibrillation","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":327.2705742509355,"d":"327"},{"v":1.549158567402372E-29,"d":"2E-29"},90,"Atrial fibrillation","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":371.9345717946403,"d":"372"},{"v":2.285801846779733e-32,"d":"2E-32"},106,"Atrial fibrillation","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":1365.076251295229,"d":"1365"},{"v":4.940294343100347e-236,"d":"5E-236"},78,"Coronary artery disease","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":1302.544517507379,"d":"1303"},{"v":1.896921427208091e-224,"d":"2E-224"},76,"Coronary artery disease","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":1591.496785743608,"d":"1591"},{"v":1.845882420247325e-285,"d":"2E-285"},74,"Coronary artery disease","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":1747.262364126949,"d":"1747"},{"v":4.484620588636909e-307,"d":"4E-307"},90,"Coronary artery disease","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":1585.834624944105,"d":"1586"},{"v":1.402668106276183e-264,"d":"1E-264"},106,"Coronary artery disease","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":73.92400107955369,"d":"74"},{"v":228.0681599912766,"d":"228"},{"v":4.116095999868705e-18,"d":"4E-18"},75,"Heart failure","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":86.12612967283262,"d":"86"},{"v":225.0703491900102,"d":"225"},{"v":6.486676610092109e-18,"d":"6E-18"},74,"Heart failure","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":91.30677543051311,"d":"91"},{"v":190.5390902560039,"d":"191"},{"v":2.521461577760109E-13,"d":"3E-13"},72,"Heart failure","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.98992276527397,"d":"98"},{"v":238.8457954216732,"d":"239"},{"v":2.573913306435538E-16,"d":"3E-16"},89,"Heart failure","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":57.22621915186125,"d":"57"},{"v":288.4788121336392,"d":"288"},{"v":6.025722557179356e-20,"d":"6E-20"},105,"Heart failure","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":90.3828985691107,"d":"90"},{"v":0.1088370869339188,"d":"1E-01"},78,"Hemorrhagic stroke","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":78.49962647024087,"d":"78"},{"v":0.3088643791440628,"d":"3E-01"},76,"Hemorrhagic stroke","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":88.46640306330366,"d":"88"},{"v":0.07850036259798478,"d":"8E-02"},74,"Hemorrhagic stroke","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":89.39310820809487,"d":"89"},{"v":0.4089538989437884,"d":"4E-01"},90,"Hemorrhagic stroke","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":104.8065002467991,"d":"105"},{"v":0.4046564684152251,"d":"4E-01"},106,"Hemorrhagic stroke","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":240.954731576219,"d":"241"},{"v":2.702705493558862E-19,"d":"3E-19"},78,"Ischemic stroke","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":243.6510885337301,"d":"244"},{"v":3.106511304326522e-20,"d":"3E-20"},76,"Ischemic stroke","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":143.7910052769955,"d":"144"},{"v":7.3442078825434857E-7,"d":"7E-07"},74,"Ischemic stroke","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":184.2557890067416,"d":"184"},{"v":5.9505465279370053E-9,"d":"6E-09"},90,"Ischemic stroke","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":292.4419935308303,"d":"292"},{"v":2.779141371898144e-20,"d":"3E-20"},106,"Ischemic stroke","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":328.9265203374151,"d":"329"},{"v":1.643973557569765E-33,"d":"2E-33"},78,"Peripheral artery disease","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":328.9981043822853,"d":"329"},{"v":3.520165973229038e-34,"d":"4E-34"},76,"Peripheral artery disease","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":241.6229903759156,"d":"242"},{"v":1.855308260846211e-20,"d":"2E-20"},74,"Peripheral artery disease","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":313.0667348103654,"d":"313"},{"v":2.89906082825887e-27,"d":"3E-27"},90,"Peripheral artery disease","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":371.7684484089101,"d":"372"},{"v":2.429298139059054e-32,"d":"2E-32"},106,"Peripheral artery disease","Pooled"]
["Omega_3","MVMR (+ApoB)",{"v":82.22184729910202,"d":"82"},{"v":967.3593047307,"d":"967"},{"v":4.053072484150664e-155,"d":"4E-155"},78,"Venous thromboembolism","Pooled"]
["Omega_3","MVMR (+Clinical_LDL_C)",{"v":93.66629674215136,"d":"94"},{"v":941.8665332822233,"d":"942"},{"v":4.068360847668492e-151,"d":"4E-151"},76,"Venous thromboembolism","Pooled"]
["Omega_3","MVMR (+Total_FA)",{"v":90.64503587454519,"d":"91"},{"v":214.7817305096389,"d":"215"},{"v":2.259719272174324e-16,"d":"2E-16"},74,"Venous thromboembolism","Pooled"]
["Omega_3","MVMR (+Total_TG)",{"v":97.86550903133943,"d":"98"},{"v":232.3089352229083,"d":"232"},{"v":3.549884181930248E-15,"d":"4E-15"},90,"Venous thromboembolism","Pooled"]
["Omega_3","MVMR (+Total_TG+Clinical_LDL_C)",{"v":63.99249464481569,"d":"64"},{"v":959.360633019564,"d":"959"},{"v":1.948475374591623E-139,"d":"2E-139"},106,"Venous thromboembolism","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":142.5313812867016,"d":"143"},{"v":3.000259821292091E-6,"d":"3E-06"},77,"Aortic aneurysm","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":137.6793724729831,"d":"138"},{"v":1.008322052506271E-5,"d":"1E-05"},77,"Aortic aneurysm","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":153.99723671824,"d":"154"},{"v":6.7289308217715929E-8,"d":"7E-08"},75,"Aortic aneurysm","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":209.045317429061,"d":"209"},{"v":7.324406896405029e-10,"d":"7E-10"},102,"Aortic aneurysm","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":201.7177357213725,"d":"202"},{"v":6.1676772521534184E-8,"d":"6E-08"},110,"Aortic aneurysm","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":154.8907101270536,"d":"155"},{"v":1.154541820243174E-7,"d":"1E-07"},77,"Aortic valve stenosis","UKB"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":148.787332706444,"d":"149"},{"v":5.938545044073379E-7,"d":"6E-07"},77,"Aortic valve stenosis","UKB"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":152.0293183437883,"d":"152"},{"v":1.15912254690115e-07,"d":"1E-07"},75,"Aortic valve stenosis","UKB"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":201.5347148020402,"d":"202"},{"v":5.4745134025642374E-9,"d":"5E-09"},102,"Aortic valve stenosis","UKB"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":204.6820557457007,"d":"205"},{"v":2.9492740975837391E-8,"d":"3E-08"},110,"Aortic valve stenosis","UKB"]
["Omega_6","MVMR (+ApoB)",{"v":100.1869482898759,"d":"100"},{"v":152.6798892730368,"d":"153"},{"v":6.5101478448783793E-8,"d":"7E-08"},74,"Atrial fibrillation","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":119.3082989677018,"d":"119"},{"v":153.0324683786849,"d":"153"},{"v":8.79083402131238e-08,"d":"9E-08"},75,"Atrial fibrillation","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":45.73969091539676,"d":"46"},{"v":194.700000208172,"d":"195"},{"v":1.090883754809886E-13,"d":"1E-13"},73,"Atrial fibrillation","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.9803515372261,"d":"63"},{"v":292.0146319735702,"d":"292"},{"v":2.062107568708618E-21,"d":"2E-21"},100,"Atrial fibrillation","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.8595094648695,"d":"53"},{"v":298.2017065224388,"d":"298"},{"v":1.209881484749457E-20,"d":"1E-20"},108,"Atrial fibrillation","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":903.689606772926,"d":"904"},{"v":6.4765340109133e-143,"d":"6E-143"},77,"Coronary artery disease","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":981.2147937784209,"d":"981"},{"v":1.823178585740086E-158,"d":"2E-158"},77,"Coronary artery disease","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":1328.842242390776,"d":"1329"},{"v":1.739100484885501e-230,"d":"2E-230"},75,"Coronary artery disease","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":1520.04591892235,"d":"1520"},{"v":5.457773163362111e-253,"d":"5E-253"},102,"Coronary artery disease","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":1094.881234258903,"d":"1095"},{"v":6.02131160321411e-164,"d":"6E-164"},110,"Coronary artery disease","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":100.0928137816582,"d":"100"},{"v":194.8961741793817,"d":"195"},{"v":1.726079270727743e-13,"d":"2E-13"},74,"Heart failure","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":119.2506423998779,"d":"119"},{"v":200.2166675255847,"d":"200"},{"v":5.118540164006715E-14,"d":"5E-14"},75,"Heart failure","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":46.08024412169922,"d":"46"},{"v":209.5427601727681,"d":"210"},{"v":4.347610713917939e-16,"d":"4E-16"},72,"Heart failure","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":63.1980061822221,"d":"63"},{"v":269.2549305671602,"d":"269"},{"v":2.35819656975315e-18,"d":"2E-18"},99,"Heart failure","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.87532295599432,"d":"53"},{"v":260.4576440798808,"d":"260"},{"v":2.061595952879333E-15,"d":"2E-15"},108,"Heart failure","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":82.47750001656222,"d":"82"},{"v":0.2338536048399344,"d":"2E-01"},77,"Hemorrhagic stroke","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":82.52065556319357,"d":"83"},{"v":0.2328440920005128,"d":"2E-01"},77,"Hemorrhagic stroke","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":84.44981434349101,"d":"84"},{"v":0.1496559609100815,"d":"1E-01"},75,"Hemorrhagic stroke","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":106.8110956504027,"d":"107"},{"v":0.2781837780462704,"d":"3E-01"},102,"Hemorrhagic stroke","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":109.0787564049259,"d":"109"},{"v":0.3993095943227924,"d":"4E-01"},110,"Hemorrhagic stroke","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":177.6287848905209,"d":"178"},{"v":1.673950665670642E-10,"d":"2E-10"},77,"Ischemic stroke","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":194.3603964539063,"d":"194"},{"v":9.42860576321838e-13,"d":"9E-13"},77,"Ischemic stroke","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":214.5465092975286,"d":"215"},{"v":4.300411513483032e-16,"d":"4E-16"},75,"Ischemic stroke","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":253.3485584809774,"d":"253"},{"v":1.717407369131877E-15,"d":"2E-15"},102,"Ischemic stroke","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":236.2146143212604,"d":"236"},{"v":6.390470643977556E-12,"d":"6E-12"},110,"Ischemic stroke","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":224.2602254790901,"d":"224"},{"v":4.870242624223451e-17,"d":"5E-17"},77,"Peripheral artery disease","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":236.3258266824833,"d":"236"},{"v":7.531092296000599e-19,"d":"8E-19"},77,"Peripheral artery disease","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":219.3899765914675,"d":"219"},{"v":8.253834397180625e-17,"d":"8E-17"},75,"Peripheral artery disease","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":277.6385588121073,"d":"278"},{"v":7.35607007913698e-19,"d":"7E-19"},102,"Peripheral artery disease","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":270.1733625857403,"d":"270"},{"v":2.665285109490756e-16,"d":"3E-16"},110,"Peripheral artery disease","Pooled"]
["Omega_6","MVMR (+ApoB)",{"v":96.67682100908796,"d":"97"},{"v":923.1881616222718,"d":"923"},{"v":8.132981301601499e-147,"d":"8E-147"},77,"Venous thromboembolism","Pooled"]
["Omega_6","MVMR (+Clinical_LDL_C)",{"v":116.9083266127758,"d":"117"},{"v":917.2572837071945,"d":"917"},{"v":1.251969828738504e-145,"d":"1E-145"},77,"Venous thromboembolism","Pooled"]
["Omega_6","MVMR (+Total_FA)",{"v":44.63157043574238,"d":"45"},{"v":936.5740564142234,"d":"937"},{"v":1.296807188763721E-150,"d":"1E-150"},75,"Venous thromboembolism","Pooled"]
["Omega_6","MVMR (+Total_TG)",{"v":62.03181523155622,"d":"62"},{"v":955.497352720705,"d":"955"},{"v":3.681623442202843e-140,"d":"4E-140"},102,"Venous thromboembolism","Pooled"]
["Omega_6","MVMR (+Total_TG+Clinical_LDL_C)",{"v":52.05609848905957,"d":"52"},{"v":968.8928104002763,"d":"969"},{"v":2.415031113680826E-139,"d":"2E-139"},110,"Venous thromboembolism","Pooled"]

{"sheet":"ST12","index":21,"n_rows":37,"n_cols":8,"rows_kept":37}
["outcome","exposure","method","nsnp","OR","95% CI","pval","FADS excluded"]
["Coronary artery disease","Apolipoprotein B","Inverse variance weighted",57,{"v":1.5528411410318155,"d":"1.55"},"(1.41; 1.71)",1.35279473498293E-18,"no"]
["Coronary artery disease","Apolipoprotein B","Inverse variance weighted",56,{"v":1.5534552954443919,"d":"1.55"},"(1.41; 1.72)",3.95025087116693e-18,"yes"]
["Ischemic stroke","Apolipoprotein B","Inverse variance weighted",57,{"v":1.0830014813304105,"d":"1.08"},"(0.99; 1.19)",0.0928607845427351,"no"]
["Ischemic stroke","Apolipoprotein B","Inverse variance weighted",56,{"v":1.0741995272451048,"d":"1.07"},"(0.98; 1.18)",0.130124684432754,"yes"]
["Hemorrhagic stroke","Apolipoprotein B","Inverse variance weighted",57,{"v":0.9437165458487824,"d":"0.94"},"(0.84; 1.06)",0.323936451609497,"no"]
["Hemorrhagic stroke","Apolipoprotein B","Inverse variance weighted",56,{"v":0.944484368110276,"d":"0.94"},"(0.84; 1.06)",0.333416090922763,"yes"]
["Heart failure","Apolipoprotein B","Inverse variance weighted",54,{"v":1.130146334616495,"d":"1.13"},"(1.05; 1.22)",0.00211360568586798,"no"]
["Heart failure","Apolipoprotein B","Inverse variance weighted",53,{"v":1.1239573185846057,"d":"1.12"},"(1.04; 1.22)",0.00351609140965933,"yes"]
["Atrial fibrillation","Apolipoprotein B","Inverse variance weighted",46,{"v":1.0611269886822587,"d":"1.06"},"(0.99; 1.14)",0.0933308864745071,"no"]
["Atrial fibrillation","Apolipoprotein B","Inverse variance weighted",45,{"v":1.054196187729032,"d":"1.05"},"(0.98; 1.13)",0.136293615340187,"yes"]
["Peripheral artery disease","Apolipoprotein B","Inverse variance weighted",57,{"v":1.2334818018499933,"d":"1.23"},"(1.07; 1.43)",0.00495786730262426,"no"]
["Peripheral artery disease","Apolipoprotein B","Inverse variance weighted",56,{"v":1.2126003837337402,"d":"1.21"},"(1.05; 1.4)",0.00794608761145233,"yes"]
["Aortic aneurysm","Apolipoprotein B","Inverse variance weighted",57,{"v":1.0960173306631924,"d":"1.10"},"(0.95; 1.27)",0.216633493188813,"no"]
["Aortic aneurysm","Apolipoprotein B","Inverse variance weighted",56,{"v":1.0844617707475936,"d":"1.08"},"(0.94; 1.25)",0.274986164778079,"yes"]
["Venous thromboembolism","Apolipoprotein B","Inverse variance weighted",57,{"v":0.9636085571109274,"d":"0.96"},"(0.79; 1.18)",0.717384390824528,"no"]
["Venous thromboembolism","Apolipoprotein B","Inverse variance weighted",56,{"v":0.9494883949987524,"d":"0.95"},"(0.78; 1.16)",0.61101112746754,"yes"]
["Aortic valve stenosis","Apolipoprotein B","Inverse variance weighted",57,{"v":1.4430547677221812,"d":"1.44"},"(1.19; 1.75)",0.000159506580391979,"no"]
["Aortic valve stenosis","Apolipoprotein B","Inverse variance weighted",56,{"v":1.4293509737776329,"d":"1.43"},"(1.18; 1.73)",0.000247347951134739,"yes"]
["Coronary artery disease","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":1.5462116745127976,"d":"1.55"},"(1.43; 1.68)",1.21789341684139E-25,"no"]
["Coronary artery disease","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":1.551870083804605,"d":"1.55"},"(1.43; 1.69)",3.99641333943769e-25,"yes"]
["Ischemic stroke","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":1.1343377437519753,"d":"1.13"},"(1.05; 1.23)",0.00198772010168483,"no"]
["Ischemic stroke","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":1.1222224231802116,"d":"1.12"},"(1.04; 1.22)",0.00477864782321188,"yes"]
["Hemorrhagic stroke","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":0.9096914992916562,"d":"0.91"},"(0.81; 1.02)",0.104202419340961,"no"]
["Hemorrhagic stroke","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":0.9096533396896973,"d":"0.91"},"(0.81; 1.02)",0.107868491801168,"yes"]
["Heart failure","Clinical LDL cholesterol","Inverse variance weighted",47,{"v":1.1345882287412525,"d":"1.13"},"(1.06; 1.22)",0.000547712573199378,"no"]
["Heart failure","Clinical LDL cholesterol","Inverse variance weighted",46,{"v":1.1258581689193445,"d":"1.13"},"(1.05; 1.21)",1.41599473652496E-3,"yes"]
["Atrial fibrillation","Clinical LDL cholesterol","Inverse variance weighted",42,{"v":1.0568393410442418,"d":"1.06"},"(0.99; 1.13)",0.0836652446286174,"no"]
["Atrial fibrillation","Clinical LDL cholesterol","Inverse variance weighted",41,{"v":1.047821501380602,"d":"1.05"},"(0.98; 1.12)",0.147691359024253,"yes"]
["Peripheral artery disease","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":1.2503416052908953,"d":"1.25"},"(1.08; 1.45)",0.00269478733492597,"no"]
["Peripheral artery disease","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":1.2223795119124514,"d":"1.22"},"(1.06; 1.41)",0.00587302123741061,"yes"]
["Aortic aneurysm","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":1.1735956219712087,"d":"1.17"},"(1.02; 1.35)",0.0242863823598044,"no"]
["Aortic aneurysm","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":1.1583704334837919,"d":"1.16"},"(1.01; 1.33)",0.0406457064932365,"yes"]
["Venous thromboembolism","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":0.9855639171243155,"d":"0.99"},"(0.8; 1.21)",0.888806382652483,"no"]
["Venous thromboembolism","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":0.9658827690617494,"d":"0.97"},"(0.79; 1.18)",0.738512342620392,"yes"]
["Aortic valve stenosis","Clinical LDL cholesterol","Inverse variance weighted",49,{"v":1.3499967900853085,"d":"1.35"},"(1.13; 1.61)",8.10891082197782E-4,"no"]
["Aortic valve stenosis","Clinical LDL cholesterol","Inverse variance weighted",48,{"v":1.3337234202290926,"d":"1.33"},"(1.12; 1.59)",1.4212680223826E-3,"yes"]