ensemble_id	gene	p_val	avg_log2FC	pct.1	pct.2	p_val_adj	cluster	gene_diff	gene_type	gene_description	GO_id	GO_term	pathway	pathway_description
ENSMUSG00000031444	F10	0	1.685344023	0.724	0.255	0	1	2.839	protein_coding	coagulation factor X [Source:MGI Symbol;Acc:MGI:103107]	"GO:0005576,GO:0006508,GO:0004252,GO:0005509,GO:0007596,GO:0005615,GO:0016787,GO:0008233,GO:0016020,GO:0005783,GO:0043231,GO:0008236,GO:0051897,GO:0007599,GO:0005543"	extracellular region|proteolysis|serine-type endopeptidase activity|calcium ion binding|blood coagulation|extracellular space|hydrolase activity|peptidase activity|membrane|endoplasmic reticulum|intracellular membrane-bounded organelle|serine-type peptidase activity|positive regulation of protein kinase B signaling|hemostasis|phospholipid binding	mmu04610	Complement and coagulation cascades
ENSMUSG00000020826	Nos2	8.15E-301	1.155595707	0.431	0.114	2.63E-296	1	3.781	protein_coding	"nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]"	"GO:0050660,GO:0055114,GO:0016491,GO:0010181,GO:0020037,GO:0050661,GO:0005516,GO:0004517,GO:0006809,GO:0046872,GO:0042742,GO:0005615,GO:0005634,GO:0048471,GO:0005829,GO:0005515,GO:0005737,GO:0003779,GO:0042803,GO:0005886,GO:0009617,GO:0045859,GO:0010629,GO:0071222,GO:0071346,GO:0019901,GO:0001666,GO:0003958,GO:0050796,GO:0071345,GO:0006954,GO:0006801,GO:0008013,GO:0007623,GO:0042127,GO:0032496,GO:0005777,GO:0045296,GO:0035690,GO:0071407,GO:0012506,GO:0032310,GO:0050998,GO:0051879,GO:1900015,GO:0051712,GO:0030863,GO:0009725,GO:0008603,GO:0006527,GO:0072604,GO:0072606,GO:0034617,GO:0034618,GO:0007263,GO:0018119,GO:0031284,GO:0042177,GO:0045776"	flavin adenine dinucleotide binding|oxidation-reduction process|oxidoreductase activity|FMN binding|heme binding|NADP binding|calmodulin binding|nitric-oxide synthase activity|nitric oxide biosynthetic process|metal ion binding|defense response to bacterium|extracellular space|nucleus|perinuclear region of cytoplasm|cytosol|protein binding|cytoplasm|actin binding|protein homodimerization activity|plasma membrane|response to bacterium|regulation of protein kinase activity|negative regulation of gene expression|cellular response to lipopolysaccharide|cellular response to interferon-gamma|protein kinase binding|response to hypoxia|NADPH-hemoprotein reductase activity|regulation of insulin secretion|cellular response to cytokine stimulus|inflammatory response|superoxide metabolic process|beta-catenin binding|circadian rhythm|regulation of cell population proliferation|response to lipopolysaccharide|peroxisome|cadherin binding|cellular response to drug|cellular response to organic cyclic compound|vesicle membrane|prostaglandin secretion|nitric-oxide synthase binding|Hsp90 protein binding|regulation of cytokine production involved in inflammatory response|positive regulation of killing of cells of other organism|cortical cytoskeleton|response to hormone|cAMP-dependent protein kinase regulator activity|arginine catabolic process|interleukin-6 secretion|interleukin-8 secretion|tetrahydrobiopterin binding|arginine binding|nitric oxide mediated signal transduction|peptidyl-cysteine S-nitrosylation|positive regulation of guanylate cyclase activity|negative regulation of protein catabolic process|negative regulation of blood pressure	"mmu00220,mmu00330,mmu04371,mmu04066,mmu04020,mmu04146,mmu04926,mmu05200,mmu05222,mmu05132,mmu05133,mmu05152,mmu05146,mmu05145,mmu05140,mmu05142"	Arginine biosynthesis|Arginine and proline metabolism|Apelin signaling pathway|HIF-1 signaling pathway|Calcium signaling pathway|Peroxisome|Relaxin signaling pathway|Pathways in cancer|Small cell lung cancer|Salmonella infection|Pertussis|Tuberculosis|Amoebiasis|Toxoplasmosis|Leishmaniasis|Chagas disease (American trypanosomiasis)
ENSMUSG00000078566	Bnip3	1.65E-261	0.938799097	0.511	0.183	5.33E-257	1	2.792	protein_coding	BCL2/adenovirus E1B interacting protein 3 [Source:MGI Symbol;Acc:MGI:109326]	"GO:0016021,GO:0005740,GO:0043065,GO:0016020,GO:0005634,GO:0005654,GO:0005737,GO:0042802,GO:0042803,GO:0046982,GO:0051607,GO:0014069,GO:0005739,GO:0009617,GO:0005635,GO:0005783,GO:0051561,GO:0060548,GO:0006915,GO:0030425,GO:0051020,GO:0001666,GO:0010917,GO:0031966,GO:0005741,GO:0051402,GO:0008219,GO:0070301,GO:0072593,GO:1901998,GO:0035694,GO:0071456,GO:0005515,GO:0010666,GO:0097345,GO:0046902,GO:0090200,GO:0097193,GO:0050873,GO:0008626,GO:0010637,GO:0010659,GO:0010940,GO:0016239,GO:0043068,GO:0043243,GO:0043653,GO:0045837,GO:0048102,GO:0071279,GO:0090141,GO:1902109,GO:1903599,GO:1990144,GO:0010821,GO:0021987,GO:0043066,GO:0048709,GO:0055093,GO:0071260,GO:1903715,GO:2000378,GO:0031307"	integral component of membrane|mitochondrial envelope|positive regulation of apoptotic process|membrane|nucleus|nucleoplasm|cytoplasm|identical protein binding|protein homodimerization activity|protein heterodimerization activity|defense response to virus|postsynaptic density|mitochondrion|response to bacterium|nuclear envelope|endoplasmic reticulum|positive regulation of mitochondrial calcium ion concentration|negative regulation of cell death|apoptotic process|dendrite|GTPase binding|response to hypoxia|negative regulation of mitochondrial membrane potential|mitochondrial membrane|mitochondrial outer membrane|neuron apoptotic process|cell death|cellular response to hydrogen peroxide|reactive oxygen species metabolic process|toxin transport|mitochondrial protein catabolic process|cellular response to hypoxia|protein binding|positive regulation of cardiac muscle cell apoptotic process|mitochondrial outer membrane permeabilization|regulation of mitochondrial membrane permeability|positive regulation of release of cytochrome c from mitochondria|intrinsic apoptotic signaling pathway|brown fat cell differentiation|granzyme-mediated apoptotic signaling pathway|negative regulation of mitochondrial fusion|cardiac muscle cell apoptotic process|positive regulation of necrotic cell death|positive regulation of macroautophagy|positive regulation of programmed cell death|positive regulation of protein complex disassembly|mitochondrial fragmentation involved in apoptotic process|negative regulation of membrane potential|autophagic cell death|cellular response to cobalt ion|positive regulation of mitochondrial fission|negative regulation of mitochondrial membrane permeability involved in apoptotic process|positive regulation of autophagy of mitochondrion|intrinsic apoptotic signaling pathway in response to hypoxia|regulation of mitochondrion organization|cerebral cortex development|negative regulation of apoptotic process|oligodendrocyte differentiation|response to hyperoxia|cellular response to mechanical stimulus|regulation of aerobic respiration|negative regulation of reactive oxygen species metabolic process|integral component of mitochondrial outer membrane	"mmu04068,mmu04140,mmu04137,mmu05134"	FoxO signaling pathway|Autophagy - animal|Mitophagy - animal|Legionellosis
ENSMUSG00000042349	Ikbke	3.94E-236	0.890505159	0.434	0.143	1.27E-231	1	3.035	protein_coding	inhibitor of kappaB kinase epsilon [Source:MGI Symbol;Acc:MGI:1929612]	"GO:0005524,GO:0006468,GO:0004672,GO:0016740,GO:0005634,GO:0005737,GO:0000166,GO:0051260,GO:0016301,GO:0016310,GO:0006974,GO:0004674,GO:0007252,GO:0016605,GO:0008630,GO:0031966,GO:0005515,GO:0031625,GO:0060340,GO:0043123,GO:0034340,GO:0098586,GO:0035456,GO:0018105,GO:0036435,GO:0004704,GO:0038061,GO:0010884,GO:0008384"	ATP binding|protein phosphorylation|protein kinase activity|transferase activity|nucleus|cytoplasm|nucleotide binding|protein homooligomerization|kinase activity|phosphorylation|cellular response to DNA damage stimulus|protein serine/threonine kinase activity|I-kappaB phosphorylation|PML body|intrinsic apoptotic signaling pathway in response to DNA damage|mitochondrial membrane|protein binding|ubiquitin protein ligase binding|positive regulation of type I interferon-mediated signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to type I interferon|cellular response to virus|response to interferon-beta|peptidyl-serine phosphorylation|K48-linked polyubiquitin modification-dependent protein binding|NF-kappaB-inducing kinase activity|NIK/NF-kappaB signaling|positive regulation of lipid storage|IkappaB kinase activity	"mmu04620,mmu04621,mmu04622,mmu04623,mmu04625,mmu04657,mmu05162,mmu05164,mmu05161,mmu05160,mmu05168,mmu05167,mmu05165"	Toll-like receptor signaling pathway|NOD-like receptor signaling pathway|RIG-I-like receptor signaling pathway|Cytosolic DNA-sensing pathway|C-type lectin receptor signaling pathway|IL-17 signaling pathway|Measles|Influenza A|Hepatitis B|Hepatitis C|Herpes simplex infection|Kaposi's sarcoma-associated herpesvirus infection|Human papillomavirus infection
ENSMUSG00000028412	Slc44a1	3.75E-224	0.806825325	0.407	0.133	1.21E-219	1	3.06	protein_coding	"solute carrier family 44, member 1 [Source:MGI Symbol;Acc:MGI:2140592]"	"GO:0016020,GO:0016021,GO:0005886,GO:0005654,GO:0005739,GO:0005741,GO:0015871,GO:0015220"	membrane|integral component of membrane|plasma membrane|nucleoplasm|mitochondrion|mitochondrial outer membrane|choline transport|choline transmembrane transporter activity	mmu05231	Choline metabolism in cancer
ENSMUSG00000020277	Pfkl	1.03E-219	0.752239787	0.466	0.175	3.33E-215	1	2.663	protein_coding	"phosphofructokinase, liver, B-type [Source:MGI Symbol;Acc:MGI:97547]"	"GO:0003872,GO:0006096,GO:0005524,GO:0005737,GO:0006002,GO:0016740,GO:0046872,GO:0003824,GO:0008152,GO:0005829,GO:0000166,GO:0042802,GO:0016301,GO:0016310,GO:0016020,GO:0046676,GO:0019900,GO:0051289,GO:0030388,GO:0009749,GO:0061615,GO:0070061,GO:0005975,GO:0048029,GO:0016208,GO:0070095,GO:0006007,GO:0061621,GO:0005945"	"6-phosphofructokinase activity|glycolytic process|ATP binding|cytoplasm|fructose 6-phosphate metabolic process|transferase activity|metal ion binding|catalytic activity|metabolic process|cytosol|nucleotide binding|identical protein binding|kinase activity|phosphorylation|membrane|negative regulation of insulin secretion|kinase binding|protein homotetramerization|fructose 1,6-bisphosphate metabolic process|response to glucose|glycolytic process through fructose-6-phosphate|fructose binding|carbohydrate metabolic process|monosaccharide binding|AMP binding|fructose-6-phosphate binding|glucose catabolic process|canonical glycolysis|6-phosphofructokinase complex"	"mmu00010,mmu00030,mmu00051,mmu00052,mmu03018,mmu04066,mmu04152,mmu04922,mmu05230"	Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|RNA degradation|HIF-1 signaling pathway|AMPK signaling pathway|Glucagon signaling pathway|Central carbon metabolism in cancer
ENSMUSG00000062421	Arf2	2.83E-172	0.77860242	0.266	0.071	9.14E-168	1	3.746	protein_coding	ADP-ribosylation factor 2 [Source:MGI Symbol;Acc:MGI:99595]	"GO:0005525,GO:0005794,GO:0015031,GO:0000166,GO:0005886,GO:0005737,GO:0016192,GO:0006886"	GTP binding|Golgi apparatus|protein transport|nucleotide binding|plasma membrane|cytoplasm|vesicle-mediated transport|intracellular protein transport	--	--
ENSMUSG00000033066	Gas7	2.88E-166	0.711979711	0.303	0.094	9.30E-162	1	3.223	protein_coding	growth arrest specific 7 [Source:MGI Symbol;Acc:MGI:1202388]	GO:0005515	protein binding	--	--
ENSMUSG00000036053	Fmnl2	1.98E-144	0.568442402	0.3	0.101	6.39E-140	1	2.97	protein_coding	formin-like 2 [Source:MGI Symbol;Acc:MGI:1918659]	"GO:0003779,GO:0007010,GO:0030036,GO:0016043,GO:0017048,GO:0022604,GO:0005829,GO:0005737,GO:0008360,GO:0030866,GO:0032794"	actin binding|cytoskeleton organization|actin cytoskeleton organization|cellular component organization|Rho GTPase binding|regulation of cell morphogenesis|cytosol|cytoplasm|regulation of cell shape|cortical actin cytoskeleton organization|GTPase activating protein binding	--	--
ENSMUSG00000035105	Egln3	2.68E-126	0.582189074	0.285	0.101	8.66E-122	1	2.822	protein_coding	egl-9 family hypoxia-inducible factor 3 [Source:MGI Symbol;Acc:MGI:1932288]	"GO:0055114,GO:0016491,GO:0005506,GO:0016705,GO:0031418,GO:0016706,GO:0031545,GO:0001666,GO:0006915,GO:0006919,GO:0018126,GO:0018401,GO:0042127,GO:0005634,GO:0005737,GO:0005829"	"oxidation-reduction process|oxidoreductase activity|iron ion binding|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|L-ascorbic acid binding|2-oxoglutarate-dependent dioxygenase activity|peptidyl-proline 4-dioxygenase activity|response to hypoxia|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|protein hydroxylation|peptidyl-proline hydroxylation to 4-hydroxy-L-proline|regulation of cell population proliferation|nucleus|cytoplasm|cytosol"	"mmu04066,mmu05200,mmu05211"	HIF-1 signaling pathway|Pathways in cancer|Renal cell carcinoma
ENSMUSG00000020641	Rsad2	0	2.110874163	0.603	0.184	0	2	3.277	protein_coding	radical S-adenosyl methionine domain containing 2 [Source:MGI Symbol;Acc:MGI:1929628]	"GO:0003824,GO:0051536,GO:0016020,GO:0046872,GO:0051607,GO:0005783,GO:0005515,GO:0002376,GO:0045087,GO:0005789,GO:0005739,GO:0051539,GO:0001503,GO:0001650,GO:0009615,GO:0003674,GO:0005743,GO:0043621,GO:0005811,GO:0005741,GO:0030278,GO:0045071,GO:0050709,GO:0034157,GO:0034165,GO:2000553,GO:0035710,GO:0043367"	"catalytic activity|iron-sulfur cluster binding|membrane|metal ion binding|defense response to virus|endoplasmic reticulum|protein binding|immune system process|innate immune response|endoplasmic reticulum membrane|mitochondrion|4 iron, 4 sulfur cluster binding|ossification|fibrillar center|response to virus|molecular_function|mitochondrial inner membrane|protein self-association|lipid droplet|mitochondrial outer membrane|regulation of ossification|negative regulation of viral genome replication|negative regulation of protein secretion|positive regulation of toll-like receptor 7 signaling pathway|positive regulation of toll-like receptor 9 signaling pathway|positive regulation of T-helper 2 cell cytokine production|CD4-positive, alpha-beta T cell activation|CD4-positive, alpha-beta T cell differentiation"	mmu05164	Influenza A
ENSMUSG00000041827	Oasl1	0	1.634560872	0.499	0.098	0	2	5.092	protein_coding	2'-5' oligoadenylate synthetase-like 1 [Source:MGI Symbol;Acc:MGI:2180849]	"GO:0005524,GO:0005515,GO:0003723,GO:0006955,GO:0016740,GO:0003725,GO:0051607,GO:0003677,GO:0005634,GO:0005654,GO:0005829,GO:0005737,GO:0002376,GO:0045087,GO:0005730,GO:0045071,GO:0060700,GO:0009615"	ATP binding|protein binding|RNA binding|immune response|transferase activity|double-stranded RNA binding|defense response to virus|DNA binding|nucleus|nucleoplasm|cytosol|cytoplasm|immune system process|innate immune response|nucleolus|negative regulation of viral genome replication|regulation of ribonuclease activity|response to virus	mmu05165	Human papillomavirus infection
ENSMUSG00000105504	Gbp5	0	1.324194192	0.369	0.067	0	2	5.507	protein_coding	guanylate binding protein 5 [Source:MGI Symbol;Acc:MGI:2429943]	"GO:0005525,GO:0003924,GO:0016020,GO:0000139,GO:0005794,GO:0016787,GO:0048471,GO:0005737,GO:0000166,GO:0042802,GO:0042803,GO:0031410,GO:0009617,GO:0005515,GO:0002376,GO:0071346,GO:0006954,GO:0051289,GO:1900017,GO:0034067,GO:0045089,GO:0050702,GO:1900227,GO:0072616"	GTP binding|GTPase activity|membrane|Golgi membrane|Golgi apparatus|hydrolase activity|perinuclear region of cytoplasm|cytoplasm|nucleotide binding|identical protein binding|protein homodimerization activity|cytoplasmic vesicle|response to bacterium|protein binding|immune system process|cellular response to interferon-gamma|inflammatory response|protein homotetramerization|positive regulation of cytokine production involved in inflammatory response|protein localization to Golgi apparatus|positive regulation of innate immune response|interleukin-1 beta secretion|positive regulation of NLRP3 inflammasome complex assembly|interleukin-18 secretion	mmu04621	NOD-like receptor signaling pathway
ENSMUSG00000078920	Ifi47	4.63E-276	1.095355414	0.345	0.068	1.49E-271	2	5.074	protein_coding	interferon gamma inducible protein 47	"GO:0003924,GO:0005525,GO:0005789,GO:0005794,GO:0006952,GO:0035458,GO:0045087"	GTPase activity|GTP binding|endoplasmic reticulum membrane|Golgi apparatus|defense response|cellular response to interferon-beta|innate immune response	mmu04668	TNF signaling pathway
ENSMUSG00000070327	Rnf213	9.72E-275	1.290898708	0.498	0.155	3.14E-270	2	3.213	protein_coding	ring finger protein 213 [Source:MGI Symbol;Acc:MGI:1289196]	"GO:0004842,GO:0016887,GO:0016567,GO:0016740,GO:0046872,GO:0016787,GO:0005829,GO:0005737,GO:0051260,GO:0006511,GO:0005730,GO:0001525,GO:0051865,GO:0002040,GO:2000051"	ubiquitin-protein transferase activity|ATPase activity|protein ubiquitination|transferase activity|metal ion binding|hydrolase activity|cytosol|cytoplasm|protein homooligomerization|ubiquitin-dependent protein catabolic process|nucleolus|angiogenesis|protein autoubiquitination|sprouting angiogenesis|negative regulation of non-canonical Wnt signaling pathway	--	--
ENSMUSG00000046879	Irgm1	3.04E-233	0.981053254	0.358	0.086	9.83E-229	2	4.163	protein_coding	immunity-related GTPase family M protein 1 isoform 1	"GO:0000045,GO:0000139,GO:0000421,GO:0001891,GO:0003924,GO:0005525,GO:0005764,GO:0005765,GO:0005770,GO:0005776,GO:0005783,GO:0005789,GO:0006952,GO:0009617,GO:0030670,GO:0031902,GO:0035458,GO:0042995,GO:0044754,GO:0045335,GO:0060335,GO:0071346,GO:0075044,GO:1901098"	autophagosome assembly|Golgi membrane|autophagosome membrane|phagocytic cup|GTPase activity|GTP binding|lysosome|lysosomal membrane|late endosome|autophagosome|endoplasmic reticulum|endoplasmic reticulum membrane|defense response|response to bacterium|phagocytic vesicle membrane|late endosome membrane|cellular response to interferon-beta|cell projection|autolysosome|phagocytic vesicle|positive regulation of interferon-gamma-mediated signaling pathway|cellular response to interferon-gamma|autophagy of host cells involved in interaction with symbiont|positive regulation of autophagosome maturation	mmu05145	Toxoplasmosis
ENSMUSG00000054404	Slfn5	4.73E-227	1.084406188	0.343	0.081	1.53E-222	2	4.235	protein_coding	schlafen 5 [Source:MGI Symbol;Acc:MGI:1329004]	"GO:0005634,GO:0005524,GO:0000166,GO:0030154"	nucleus|ATP binding|nucleotide binding|cell differentiation	--	--
ENSMUSG00000034459	Ifit1	5.74E-211	1.232273417	0.251	0.044	1.85E-206	2	5.705	protein_coding	interferon-induced protein with tetratricopeptide repeats 1 [Source:MGI Symbol;Acc:MGI:99450]	"GO:0005515,GO:0005829,GO:0003723,GO:0005737,GO:0051607,GO:0009617,GO:0002376,GO:0045087,GO:0035458,GO:0009615,GO:0035457"	protein binding|cytosol|RNA binding|cytoplasm|defense response to virus|response to bacterium|immune system process|innate immune response|cellular response to interferon-beta|response to virus|cellular response to interferon-alpha	"mmu05160,mmu05168"	Hepatitis C|Herpes simplex infection
ENSMUSG00000025498	Irf7	1.70E-193	0.827714259	0.362	0.108	5.48E-189	2	3.352	protein_coding	interferon regulatory factor 7 [Source:MGI Symbol;Acc:MGI:1859212]	"GO:0006355,GO:0005515,GO:0003700,GO:0044212,GO:0016064,GO:0003677,GO:0005634,GO:0005654,GO:0005829,GO:0010468,GO:0005737,GO:0045944,GO:0051607,GO:0045893,GO:0000978,GO:0002376,GO:0045087,GO:0000981,GO:0032728,GO:0060340,GO:0032727,GO:0060337,GO:0032481,GO:0001158,GO:0045088,GO:0002819,GO:0034124,GO:0045351,GO:0000987,GO:0032607,GO:0032608,GO:0034127"	"regulation of transcription, DNA-templated|protein binding|DNA-binding transcription factor activity|transcription regulatory region DNA binding|immunoglobulin mediated immune response|DNA binding|nucleus|nucleoplasm|cytosol|regulation of gene expression|cytoplasm|positive regulation of transcription by RNA polymerase II|defense response to virus|positive regulation of transcription, DNA-templated|RNA polymerase II proximal promoter sequence-specific DNA binding|immune system process|innate immune response|DNA-binding transcription factor activity, RNA polymerase II-specific|positive regulation of interferon-beta production|positive regulation of type I interferon-mediated signaling pathway|positive regulation of interferon-alpha production|type I interferon signaling pathway|positive regulation of type I interferon production|enhancer sequence-specific DNA binding|regulation of innate immune response|regulation of adaptive immune response|regulation of MyD88-dependent toll-like receptor signaling pathway|type I interferon biosynthetic process|proximal promoter sequence-specific DNA binding|interferon-alpha production|interferon-beta production|regulation of MyD88-independent toll-like receptor signaling pathway"	"mmu04620,mmu04621,mmu04622,mmu04623,mmu05203,mmu05162,mmu05164,mmu05161,mmu05160,mmu05168,mmu05167"	Toll-like receptor signaling pathway|NOD-like receptor signaling pathway|RIG-I-like receptor signaling pathway|Cytosolic DNA-sensing pathway|Viral carcinogenesis|Measles|Influenza A|Hepatitis B|Hepatitis C|Herpes simplex infection|Kaposi's sarcoma-associated herpesvirus infection
ENSMUSG00000028128	F3	3.21E-169	0.958328848	0.273	0.067	1.04E-164	2	4.075	protein_coding	coagulation factor III [Source:MGI Symbol;Acc:MGI:88381]	"GO:0016021,GO:0005515,GO:0007596,GO:0016020"	integral component of membrane|protein binding|blood coagulation|membrane	"mmu04610,mmu04933"	Complement and coagulation cascades|AGE-RAGE signaling pathway in diabetic complications
ENSMUSG00000037095	Lrg1	0	1.876342488	0.725	0.229	0	3	3.166	protein_coding	leucine-rich alpha-2-glycoprotein 1 [Source:MGI Symbol;Acc:MGI:1924155]	"GO:0005515,GO:0005615,GO:0043231,GO:0009617,GO:0005160,GO:0030511,GO:0045766,GO:0050873,GO:0001938"	protein binding|extracellular space|intracellular membrane-bounded organelle|response to bacterium|transforming growth factor beta receptor binding|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of angiogenesis|brown fat cell differentiation|positive regulation of endothelial cell proliferation	--	--
ENSMUSG00000017737	Mmp9	0	1.241873972	0.583	0.144	0	3	4.049	protein_coding	matrix metallopeptidase 9 [Source:MGI Symbol;Acc:MGI:97011]	"GO:0008270,GO:0006508,GO:0004222,GO:0008237,GO:0031012,GO:0046872,GO:0005615,GO:0016787,GO:0032991,GO:0008233,GO:0042802,GO:0005576,GO:0001934,GO:0042493,GO:0004252,GO:0044877,GO:0004175,GO:0006979,GO:0007507,GO:0043066,GO:0051259,GO:0043065,GO:0030198,GO:0001501,GO:0062023,GO:0048771,GO:0007566,GO:0043388,GO:0030335,GO:0030574,GO:0007568,GO:0048147,GO:0045766,GO:0045742,GO:0090200,GO:2001243,GO:1904707,GO:0051549,GO:0019087,GO:0002687,GO:0001968,GO:0071276,GO:0034614,GO:1900122,GO:1904645,GO:2001258,GO:0031915,GO:2001268,GO:0071460,GO:0035987,GO:2000697"	zinc ion binding|proteolysis|metalloendopeptidase activity|metallopeptidase activity|extracellular matrix|metal ion binding|extracellular space|hydrolase activity|protein-containing complex|peptidase activity|identical protein binding|extracellular region|positive regulation of protein phosphorylation|response to drug|serine-type endopeptidase activity|protein-containing complex binding|endopeptidase activity|response to oxidative stress|heart development|negative regulation of apoptotic process|protein complex oligomerization|positive regulation of apoptotic process|extracellular matrix organization|skeletal system development|collagen-containing extracellular matrix|tissue remodeling|embryo implantation|positive regulation of DNA binding|positive regulation of cell migration|collagen catabolic process|aging|negative regulation of fibroblast proliferation|positive regulation of angiogenesis|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of release of cytochrome c from mitochondria|negative regulation of intrinsic apoptotic signaling pathway|positive regulation of vascular smooth muscle cell proliferation|positive regulation of keratinocyte migration|transformation of host cell by virus|positive regulation of leukocyte migration|fibronectin binding|cellular response to cadmium ion|cellular response to reactive oxygen species|positive regulation of receptor binding|response to amyloid-beta|negative regulation of cation channel activity|positive regulation of synaptic plasticity|negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|cellular response to cell-matrix adhesion|endodermal cell differentiation|negative regulation of epithelial cell differentiation involved in kidney development	"mmu04668,mmu04657,mmu04670,mmu04915,mmu04926,mmu05200,mmu05202,mmu05206,mmu05205,mmu05219,mmu05215,mmu05418,mmu05161,mmu01522"	TNF signaling pathway|IL-17 signaling pathway|Leukocyte transendothelial migration|Estrogen signaling pathway|Relaxin signaling pathway|Pathways in cancer|Transcriptional misregulation in cancers|MicroRNAs in cancer|Proteoglycans in cancer|Bladder cancer|Prostate cancer|Fluid shear stress and atherosclerosis|Hepatitis B|Endocrine resistance
ENSMUSG00000035493	Tgfbi	5.47E-250	1.167924926	0.501	0.145	1.77E-245	3	3.455	protein_coding	"transforming growth factor, beta induced [Source:MGI Symbol;Acc:MGI:99959]"	"GO:0007155,GO:0005518,GO:0050840,GO:0008283,GO:0005178,GO:0005515,GO:0005615,GO:0005576,GO:0031012,GO:0030198,GO:0005802,GO:0001525,GO:0002062,GO:0005604,GO:0062023,GO:0005201,GO:0050839"	cell adhesion|collagen binding|extracellular matrix binding|cell population proliferation|integrin binding|protein binding|extracellular space|extracellular region|extracellular matrix|extracellular matrix organization|trans-Golgi network|angiogenesis|chondrocyte differentiation|basement membrane|collagen-containing extracellular matrix|extracellular matrix structural constituent|cell adhesion molecule binding	--	--
ENSMUSG00000034563	Ccpg1	1.46E-187	0.870430762	0.428	0.131	4.70E-183	3	3.267	protein_coding	cell cycle progression 1 [Source:MGI Symbol;Acc:MGI:1196419]	"GO:2001106,GO:0016020,GO:0016021,GO:0045944,GO:0007049,GO:0008284,GO:0045787"	regulation of Rho guanyl-nucleotide exchange factor activity|membrane|integral component of membrane|positive regulation of transcription by RNA polymerase II|cell cycle|positive regulation of cell population proliferation|positive regulation of cell cycle	--	--
ENSMUSG00000078780	Gm5150	5.94E-184	0.789422365	0.294	0.063	1.92E-179	3	4.667	protein_coding	uncharacterized protein LOC381484 precursor	"GO:0005886,GO:0009986,GO:0016021,GO:0016477,GO:0017124,GO:0019903,GO:0022409,GO:0030695,GO:0032651,GO:0032675,GO:0032680,GO:0035696,GO:0045428,GO:0050765,GO:0050766,GO:0050870,GO:0070301,GO:0071346,GO:0071347,GO:0086080,GO:1990782"	plasma membrane|cell surface|integral component of membrane|cell migration|SH3 domain binding|protein phosphatase binding|positive regulation of cell-cell adhesion|GTPase regulator activity|regulation of interleukin-1 beta production|regulation of interleukin-6 production|regulation of tumor necrosis factor production|monocyte extravasation|regulation of nitric oxide biosynthetic process|negative regulation of phagocytosis|positive regulation of phagocytosis|positive regulation of T cell activation|cellular response to hydrogen peroxide|cellular response to interferon-gamma|cellular response to interleukin-1|protein binding involved in heterotypic cell-cell adhesion|protein tyrosine kinase binding	--	--
ENSMUSG00000005800	Mmp8	2.27E-143	0.656172659	0.372	0.114	7.32E-139	3	3.263	protein_coding	matrix metallopeptidase 8 [Source:MGI Symbol;Acc:MGI:1202395]	"GO:0008270,GO:0006508,GO:0004222,GO:0008237,GO:0031012,GO:0010629,GO:1903980,GO:0005615,GO:1901224,GO:0150078,GO:0010628,GO:1904469,GO:0046872,GO:0016787,GO:0008233,GO:0005576,GO:0004252,GO:0004175,GO:0045429,GO:0030198,GO:0005509,GO:0030574,GO:0032693,GO:0032755,GO:0035987,GO:0043388,GO:0043410,GO:0046330,GO:1903428"	zinc ion binding|proteolysis|metalloendopeptidase activity|metallopeptidase activity|extracellular matrix|negative regulation of gene expression|positive regulation of microglial cell activation|extracellular space|positive regulation of NIK/NF-kappaB signaling|positive regulation of neuroinflammatory response|positive regulation of gene expression|positive regulation of tumor necrosis factor secretion|metal ion binding|hydrolase activity|peptidase activity|extracellular region|serine-type endopeptidase activity|endopeptidase activity|positive regulation of nitric oxide biosynthetic process|extracellular matrix organization|calcium ion binding|collagen catabolic process|negative regulation of interleukin-10 production|positive regulation of interleukin-6 production|endodermal cell differentiation|positive regulation of DNA binding|positive regulation of MAPK cascade|positive regulation of JNK cascade|positive regulation of reactive oxygen species biosynthetic process	--	--
ENSMUSG00000024011	Pi16	1.81E-141	0.597628828	0.252	0.058	5.84E-137	3	4.345	protein_coding	peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:1921366]	"GO:0005576,GO:0005615,GO:0030414,GO:0010466,GO:0061052"	extracellular region|extracellular space|peptidase inhibitor activity|negative regulation of peptidase activity|negative regulation of cell growth involved in cardiac muscle cell development	--	--
ENSMUSG00000074677	Sirpb1c	1.90E-138	0.76555145	0.305	0.087	6.13E-134	3	3.506	protein_coding	unnamed protein product	GO:0016021	integral component of membrane	mmu04380	Osteoclast differentiation
ENSMUSG00000048534	Jaml	2.28E-136	0.806109747	0.312	0.09	7.36E-132	3	3.467	protein_coding	junction adhesion molecule like [Source:MGI Symbol;Acc:MGI:2685484]	"GO:0016021,GO:0016020,GO:0050900,GO:0046629,GO:0005886,GO:0030054,GO:0042803,GO:0007155,GO:0002376,GO:0005923,GO:0030593,GO:0005178,GO:0050839,GO:0007157,GO:0035696,GO:0060054,GO:0072672"	integral component of membrane|membrane|leukocyte migration|gamma-delta T cell activation|plasma membrane|cell junction|protein homodimerization activity|cell adhesion|immune system process|bicellular tight junction|neutrophil chemotaxis|integrin binding|cell adhesion molecule binding|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules|monocyte extravasation|positive regulation of epithelial cell proliferation involved in wound healing|neutrophil extravasation	--	--
ENSMUSG00000095028	Sirpb1b	9.08E-136	0.782612212	0.326	0.102	2.93E-131	3	3.196	protein_coding	signal-regulatory protein beta 1B [Source:MGI Symbol;Acc:MGI:3779828]	"GO:0016020,GO:0016021,GO:0003674,GO:0005886,GO:0022409,GO:0050766,GO:0050870"	membrane|integral component of membrane|molecular_function|plasma membrane|positive regulation of cell-cell adhesion|positive regulation of phagocytosis|positive regulation of T cell activation	mmu04380	Osteoclast differentiation
ENSMUSG00000038508	Gdf15	0	2.741413151	0.37	0.031	0	4	11.935	protein_coding	growth differentiation factor 15 [Source:MGI Symbol;Acc:MGI:1346047]	"GO:0008083,GO:0005615,GO:0005634,GO:0005794,GO:0005737,GO:0042803,GO:0005125,GO:0005576,GO:0000187,GO:0051897,GO:0042981,GO:0043410,GO:0002023,GO:1901741,GO:0005160,GO:0010862,GO:0043408,GO:0048468,GO:0060395,GO:0030509,GO:0035860,GO:0040015,GO:0060400"	growth factor activity|extracellular space|nucleus|Golgi apparatus|cytoplasm|protein homodimerization activity|cytokine activity|extracellular region|activation of MAPK activity|positive regulation of protein kinase B signaling|regulation of apoptotic process|positive regulation of MAPK cascade|reduction of food intake in response to dietary excess|positive regulation of myoblast fusion|transforming growth factor beta receptor binding|positive regulation of pathway-restricted SMAD protein phosphorylation|regulation of MAPK cascade|cell development|SMAD protein signal transduction|BMP signaling pathway|glial cell-derived neurotrophic factor receptor signaling pathway|negative regulation of multicellular organism growth|negative regulation of growth hormone receptor signaling pathway	--	--
ENSMUSG00000027698	Nceh1	4.34E-141	1.182708765	0.441	0.103	1.40E-136	4	4.282	protein_coding	neutral cholesterol ester hydrolase 1 [Source:MGI Symbol;Acc:MGI:2443191]	"GO:0016021,GO:0016787,GO:0052689,GO:0016020,GO:0006629,GO:0016042,GO:0005783,GO:0034338,GO:0009056,GO:0006470,GO:0042301,GO:0043231,GO:0006805,GO:0060395,GO:0017171"	integral component of membrane|hydrolase activity|carboxylic ester hydrolase activity|membrane|lipid metabolic process|lipid catabolic process|endoplasmic reticulum|short-chain carboxylesterase activity|catabolic process|protein dephosphorylation|phosphate ion binding|intracellular membrane-bounded organelle|xenobiotic metabolic process|SMAD protein signal transduction|serine hydrolase activity	"mmu04927,mmu04976,mmu04979,mmu04934"	Cortisol synthesis and secretion|Bile secretion|Cholesterol metabolism|Cushing's syndrome
ENSMUSG00000029919	Hpgds	4.44E-134	1.399854955	0.259	0.037	1.43E-129	4	7	protein_coding	hematopoietic prostaglandin D synthase [Source:MGI Symbol;Acc:MGI:1859384]	"GO:0005515,GO:0016740,GO:0005737,GO:0016853,GO:0042803,GO:0004364,GO:0006629,GO:0000287,GO:0006631,GO:0006633,GO:0006693,GO:0005509,GO:0006749,GO:2000255,GO:0004667,GO:0001516"	protein binding|transferase activity|cytoplasm|isomerase activity|protein homodimerization activity|glutathione transferase activity|lipid metabolic process|magnesium ion binding|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|calcium ion binding|glutathione metabolic process|negative regulation of male germ cell proliferation|prostaglandin-D synthase activity|prostaglandin biosynthetic process	"mmu00590,mmu00480,mmu00980,mmu00982,mmu05204"	Arachidonic acid metabolism|Glutathione metabolism|Metabolism of xenobiotics by cytochrome P450|Drug metabolism - cytochrome P450|Chemical carcinogenesis
ENSMUSG00000062753	AI413582	9.47E-123	0.942038602	0.369	0.082	3.06E-118	4	4.5	protein_coding	expressed sequence AI413582 [Source:MGI Symbol;Acc:MGI:2146839]	"GO:0016020,GO:0016021,GO:0003674,GO:0008150,GO:0005575"	membrane|integral component of membrane|molecular_function|biological_process|cellular_component	--	--
ENSMUSG00000024781	Lipa	1.06E-120	1.296370167	0.367	0.084	3.43E-116	4	4.369	protein_coding	lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI:96789]	"GO:0016788,GO:0048873,GO:0016787,GO:0043231,GO:0006629,GO:0016042,GO:0006954,GO:0005764,GO:0000902,GO:0001816,GO:0001650,GO:0048771,GO:0008283,GO:0030324,GO:0016125,GO:0004771,GO:0006631,GO:0016298"	"hydrolase activity, acting on ester bonds|homeostasis of number of cells within a tissue|hydrolase activity|intracellular membrane-bounded organelle|lipid metabolic process|lipid catabolic process|inflammatory response|lysosome|cell morphogenesis|cytokine production|fibrillar center|tissue remodeling|cell population proliferation|lung development|sterol metabolic process|sterol esterase activity|fatty acid metabolic process|lipase activity"	"mmu00100,mmu04142,mmu04979"	Steroid biosynthesis|Lysosome|Cholesterol metabolism
ENSMUSG00000033386	Frrs1	7.55E-114	1.031728881	0.422	0.114	2.44E-109	4	3.702	protein_coding	ferric-chelate reductase 1 [Source:MGI Symbol;Acc:MGI:108076]	"GO:0016020,GO:0016021,GO:0055114"	membrane|integral component of membrane|oxidation-reduction process	--	--
ENSMUSG00000118008	Gm36913	1.23E-111	1.072028937	0.302	0.06	3.98E-107	4	5.033	lncRNA	--	--	--	--	--
ENSMUSG00000045312	Lhfpl2	4.60E-100	1.131328654	0.348	0.086	1.48E-95	4	4.047	protein_coding	lipoma HMGIC fusion partner-like 2 [Source:MGI Symbol;Acc:MGI:2145236]	"GO:0016020,GO:0016021,GO:0003674,GO:0005575,GO:0007338,GO:0046545,GO:0046546,GO:1905516"	membrane|integral component of membrane|molecular_function|cellular_component|single fertilization|development of primary female sexual characteristics|development of primary male sexual characteristics|positive regulation of fertilization	--	--
ENSMUSG00000028278	Rragd	1.40E-86	0.876064735	0.292	0.069	4.52E-82	4	4.232	protein_coding	Ras-related GTP binding D [Source:MGI Symbol;Acc:MGI:1098604]	"GO:0005525,GO:0003924,GO:0019003,GO:0046982,GO:0051020,GO:0071233,GO:1904263,GO:1990253,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005813"	GTP binding|GTPase activity|GDP binding|protein heterodimerization activity|GTPase binding|cellular response to leucine|positive regulation of TORC1 signaling|cellular response to leucine starvation|nucleus|nucleoplasm|cytoplasm|lysosome|centrosome	"mmu04150,mmu04140"	mTOR signaling pathway|Autophagy - animal
ENSMUSG00000020422	Tns3	7.04E-75	0.79225866	0.254	0.059	2.27E-70	4	4.305	protein_coding	tensin 3 [Source:MGI Symbol;Acc:MGI:2443012]	"GO:0005515,GO:0035556,GO:0003674,GO:0005829,GO:0030054,GO:0005925,GO:0016477,GO:0008284,GO:0048286"	protein binding|intracellular signal transduction|molecular_function|cytosol|cell junction|focal adhesion|cell migration|positive regulation of cell population proliferation|lung alveolus development	--	--
ENSMUSG00000027350	Chgb	3.70E-257	3.068218612	0.325	0.028	1.19E-252	5	11.607	protein_coding	chromogranin B [Source:MGI Symbol;Acc:MGI:88395]	"GO:0030141,GO:0005615,GO:0005576,GO:0005515"	secretory granule|extracellular space|extracellular region|protein binding	--	--
ENSMUSG00000067786	Nnat	1.32E-186	3.355180483	0.368	0.055	4.26E-182	5	6.691	protein_coding	neuronatin [Source:MGI Symbol;Acc:MGI:104716]	"GO:0007420,GO:0016020,GO:0016021,GO:0005737,GO:0007275,GO:0032880,GO:0009749,GO:0032024"	brain development|membrane|integral component of membrane|cytoplasm|multicellular organism development|regulation of protein localization|response to glucose|positive regulation of insulin secretion	--	--
ENSMUSG00000067149	Jchain	7.63E-121	4.711318157	0.39	0.096	2.46E-116	5	4.062	protein_coding	immunoglobulin joining chain [Source:MGI Symbol;Acc:MGI:96493]	"GO:0034987,GO:0005615,GO:0003823,GO:0042803,GO:0005576,GO:0003697,GO:0019731,GO:0045087,GO:0042834,GO:0003094,GO:0002250,GO:0006959,GO:0031210,GO:0030674,GO:0060267,GO:0032461,GO:0019862,GO:0071748,GO:0071750,GO:0071751,GO:0071752,GO:0071756"	"immunoglobulin receptor binding|extracellular space|antigen binding|protein homodimerization activity|extracellular region|single-stranded DNA binding|antibacterial humoral response|innate immune response|peptidoglycan binding|glomerular filtration|adaptive immune response|humoral immune response|phosphatidylcholine binding|protein binding, bridging|positive regulation of respiratory burst|positive regulation of protein oligomerization|IgA binding|monomeric IgA immunoglobulin complex|dimeric IgA immunoglobulin complex|secretory IgA immunoglobulin complex|secretory dimeric IgA immunoglobulin complex|pentameric IgM immunoglobulin complex"	--	--
ENSMUSG00000049751	Rpl36al	1.86E-86	1.770000917	0.521	0.216	6.00E-82	5	2.412	protein_coding	ribosomal protein L36A-like [Source:MGI Symbol;Acc:MGI:1913733]	"GO:0003735,GO:0006412,GO:0005622,GO:0005840,GO:0003674,GO:0008150,GO:0005737,GO:0022625"	structural constituent of ribosome|translation|intracellular|ribosome|molecular_function|biological_process|cytoplasm|cytosolic large ribosomal subunit	mmu03010	Ribosome
ENSMUSG00000031762	Mt2	4.96E-83	1.965218073	0.442	0.156	1.60E-78	5	2.833	protein_coding	metallothionein 2 [Source:MGI Symbol;Acc:MGI:97172]	"GO:0046872,GO:0005634,GO:0005737,GO:0009617,GO:0008270,GO:0048471,GO:0005829,GO:0007263,GO:0006882,GO:0010273,GO:0045926,GO:0071276,GO:0071280,GO:0071294"	metal ion binding|nucleus|cytoplasm|response to bacterium|zinc ion binding|perinuclear region of cytoplasm|cytosol|nitric oxide mediated signal transduction|cellular zinc ion homeostasis|detoxification of copper ion|negative regulation of growth|cellular response to cadmium ion|cellular response to copper ion|cellular response to zinc ion	mmu04978	Mineral absorption
ENSMUSG00000002014	Ssr4	9.45E-79	2.253840699	0.46	0.193	3.05E-74	5	2.383	protein_coding	"signal sequence receptor, delta [Source:MGI Symbol;Acc:MGI:1099464]"	"GO:0016021,GO:0005783,GO:0016020,GO:0003674,GO:0008150,GO:0005789,GO:0005784"	integral component of membrane|endoplasmic reticulum|membrane|molecular_function|biological_process|endoplasmic reticulum membrane|Sec61 translocon complex	mmu04141	Protein processing in endoplasmic reticulum
ENSMUSG00000020857	Nme2	6.59E-64	1.540731783	0.447	0.187	2.13E-59	5	2.39	protein_coding	NME/NM23 nucleoside diphosphate kinase 2 [Source:MGI Symbol;Acc:MGI:97356]	"GO:0004550,GO:0006165,GO:0006183,GO:0006228,GO:0006241,GO:0016740,GO:0046872,GO:0071944,GO:0003677,GO:0005634,GO:0048471,GO:0005737,GO:0000166,GO:0005524,GO:0045944,GO:0042995,GO:0016301,GO:0007229,GO:0016310,GO:0030027,GO:0045893,GO:0005739,GO:0009117,GO:0008144,GO:0019003,GO:0010976,GO:0043066,GO:0001726,GO:0051259,GO:0031966,GO:0005515,GO:0019899,GO:0003713,GO:0005882,GO:0004674,GO:0046777,GO:0005504,GO:0006163,GO:0006220,GO:0043209,GO:0051880,GO:0045618,GO:0050679,GO:0007189,GO:0002762,GO:0019215,GO:0009142,GO:0045682,GO:0004673,GO:0018106,GO:0034599,GO:0060416,GO:0071333,GO:0071398"	"nucleoside diphosphate kinase activity|nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|transferase activity|metal ion binding|cell periphery|DNA binding|nucleus|perinuclear region of cytoplasm|cytoplasm|nucleotide binding|ATP binding|positive regulation of transcription by RNA polymerase II|cell projection|kinase activity|integrin-mediated signaling pathway|phosphorylation|lamellipodium|positive regulation of transcription, DNA-templated|mitochondrion|nucleotide metabolic process|drug binding|GDP binding|positive regulation of neuron projection development|negative regulation of apoptotic process|ruffle|protein complex oligomerization|mitochondrial membrane|protein binding|enzyme binding|transcription coactivator activity|intermediate filament|protein serine/threonine kinase activity|protein autophosphorylation|fatty acid binding|purine nucleotide metabolic process|pyrimidine nucleotide metabolic process|myelin sheath|G-quadruplex DNA binding|positive regulation of keratinocyte differentiation|positive regulation of epithelial cell proliferation|adenylate cyclase-activating G protein-coupled receptor signaling pathway|negative regulation of myeloid leukocyte differentiation|intermediate filament binding|nucleoside triphosphate biosynthetic process|regulation of epidermis development|protein histidine kinase activity|peptidyl-histidine phosphorylation|cellular response to oxidative stress|response to growth hormone|cellular response to glucose stimulus|cellular response to fatty acid"	"mmu00230,mmu00240,mmu00983"	Purine metabolism|Pyrimidine metabolism|Drug metabolism - other enzymes
ENSMUSG00000056629	Fkbp2	9.30E-59	1.443032429	0.264	0.076	3.00E-54	5	3.474	protein_coding	FK506 binding protein 2 [Source:MGI Symbol;Acc:MGI:95542]	"GO:0016020,GO:0003755,GO:0016853,GO:0005783,GO:0005789,GO:0000413"	membrane|peptidyl-prolyl cis-trans isomerase activity|isomerase activity|endoplasmic reticulum|endoplasmic reticulum membrane|protein peptidyl-prolyl isomerization	--	--
ENSMUSG00000032575	Manf	2.69E-44	1.457869351	0.327	0.136	8.69E-40	5	2.404	protein_coding	mesencephalic astrocyte-derived neurotrophic factor [Source:MGI Symbol;Acc:MGI:1922090]	"GO:0005615,GO:0005783,GO:0048471,GO:0005575,GO:0003674"	extracellular space|endoplasmic reticulum|perinuclear region of cytoplasm|cellular_component|molecular_function	--	--
ENSMUSG00000042747	Krtcap2	2.02E-40	1.274687954	0.275	0.105	6.51E-36	5	2.619	protein_coding	keratinocyte associated protein 2 [Source:MGI Symbol;Acc:MGI:1913309]	"GO:0016020,GO:0016021,GO:0005783,GO:0005789,GO:0006486,GO:0008250,GO:0042543,GO:0004579,GO:0018279"	membrane|integral component of membrane|endoplasmic reticulum|endoplasmic reticulum membrane|protein glycosylation|oligosaccharyltransferase complex|protein N-linked glycosylation via arginine|dolichyl-diphosphooligosaccharide-protein glycotransferase activity|protein N-linked glycosylation via asparagine	--	--
ENSMUSG00000064357	mt-Atp6	8.20E-166	1.958065435	0.993	0.883	2.65E-161	6	1.125	protein_coding	mitochondrially encoded ATP synthase 6 [Source:MGI Symbol;Acc:MGI:99927]	"GO:0015986,GO:0015078,GO:0045263,GO:0016020,GO:0016021,GO:0016787,GO:0006811,GO:0005739,GO:0005743,GO:0006754,GO:0016887,GO:0046933,GO:0007568,GO:0055093,GO:0005753,GO:0045259"	"ATP synthesis coupled proton transport|proton transmembrane transporter activity|proton-transporting ATP synthase complex, coupling factor F(o)|membrane|integral component of membrane|hydrolase activity|ion transport|mitochondrion|mitochondrial inner membrane|ATP biosynthetic process|ATPase activity|proton-transporting ATP synthase activity, rotational mechanism|aging|response to hyperoxia|mitochondrial proton-transporting ATP synthase complex|proton-transporting ATP synthase complex"	--	--
ENSMUSG00000064354	mt-Co2	1.79E-165	1.994838974	0.982	0.873	5.77E-161	6	1.125	protein_coding	mitochondrially encoded cytochrome c oxidase II [Source:MGI Symbol;Acc:MGI:102503]	"GO:0016021,GO:0016020,GO:0016491,GO:0005507,GO:0004129,GO:0022900,GO:0046872,GO:0055114,GO:0005739,GO:0005743,GO:1902600,GO:0070469,GO:2001171,GO:0010940,GO:0045277,GO:0010729,GO:0007595,GO:0009409,GO:0042773"	integral component of membrane|membrane|oxidoreductase activity|copper ion binding|cytochrome-c oxidase activity|electron transport chain|metal ion binding|oxidation-reduction process|mitochondrion|mitochondrial inner membrane|proton transmembrane transport|respirasome|positive regulation of ATP biosynthetic process|positive regulation of necrotic cell death|respiratory chain complex IV|positive regulation of hydrogen peroxide biosynthetic process|lactation|response to cold|ATP synthesis coupled electron transport	--	--
ENSMUSG00000064370	mt-Cytb	1.42E-153	2.051830744	0.966	0.729	4.57E-149	6	1.325	protein_coding	mitochondrially encoded cytochrome b [Source:MGI Symbol;Acc:MGI:102501]	"GO:0009055,GO:0016020,GO:0016491,GO:0006122,GO:0008121,GO:0022904,GO:0045275,GO:0016021,GO:0046872,GO:0032991,GO:0055114,GO:0005739,GO:0005743,GO:0070469,GO:0044877,GO:0051592,GO:0031305,GO:0046686,GO:0046689,GO:0015990,GO:0033762,GO:0042538,GO:0001666,GO:0007584,GO:0009408,GO:0009636,GO:0009725,GO:0010243,GO:0014070,GO:0031100,GO:0033590,GO:0042493,GO:0045471,GO:0046688,GO:0055093,GO:0009535"	"electron transfer activity|membrane|oxidoreductase activity|mitochondrial electron transport, ubiquinol to cytochrome c|ubiquinol-cytochrome-c reductase activity|respiratory electron transport chain|respiratory chain complex III|integral component of membrane|metal ion binding|protein-containing complex|oxidation-reduction process|mitochondrion|mitochondrial inner membrane|respirasome|protein-containing complex binding|response to calcium ion|integral component of mitochondrial inner membrane|response to cadmium ion|response to mercury ion|electron transport coupled proton transport|response to glucagon|hyperosmotic salinity response|response to hypoxia|response to nutrient|response to heat|response to toxic substance|response to hormone|response to organonitrogen compound|response to organic cyclic compound|animal organ regeneration|response to cobalamin|response to drug|response to ethanol|response to copper ion|response to hyperoxia|chloroplast thylakoid membrane"	--	--
ENSMUSG00000064363	mt-Nd4	8.73E-140	1.978579377	0.923	0.646	2.82E-135	6	1.429	protein_coding	mitochondrially encoded NADH dehydrogenase 4 [Source:MGI Symbol;Acc:MGI:102498]	"GO:0055114,GO:0006120,GO:0008137,GO:0042773,GO:0016020,GO:0016021,GO:0016491,GO:0005739,GO:0070469,GO:0048039,GO:0031966,GO:0007568,GO:0005747,GO:0009060,GO:0015990,GO:0003954,GO:0001666,GO:0001701,GO:0021549,GO:0035094,GO:0045471"	"oxidation-reduction process|mitochondrial electron transport, NADH to ubiquinone|NADH dehydrogenase (ubiquinone) activity|ATP synthesis coupled electron transport|membrane|integral component of membrane|oxidoreductase activity|mitochondrion|respirasome|ubiquinone binding|mitochondrial membrane|aging|mitochondrial respiratory chain complex I|aerobic respiration|electron transport coupled proton transport|NADH dehydrogenase activity|response to hypoxia|in utero embryonic development|cerebellum development|response to nicotine|response to ethanol"	--	--
ENSMUSG00000064345	mt-Nd2	7.95E-135	2.050759997	0.914	0.588	2.57E-130	6	1.554	protein_coding	mitochondrially encoded NADH dehydrogenase 2 [Source:MGI Symbol;Acc:MGI:102500]	"GO:0055114,GO:0006120,GO:0008137,GO:0016020,GO:0016021,GO:0016491,GO:0014069,GO:0005739,GO:0005743,GO:0070469,GO:0019901,GO:0072593,GO:0035255,GO:0005747"	"oxidation-reduction process|mitochondrial electron transport, NADH to ubiquinone|NADH dehydrogenase (ubiquinone) activity|membrane|integral component of membrane|oxidoreductase activity|postsynaptic density|mitochondrion|mitochondrial inner membrane|respirasome|protein kinase binding|reactive oxygen species metabolic process|ionotropic glutamate receptor binding|mitochondrial respiratory chain complex I"	--	--
ENSMUSG00000064341	mt-Nd1	1.41E-118	1.899033338	0.871	0.531	4.56E-114	6	1.64	protein_coding	mitochondrially encoded NADH dehydrogenase 1 [Source:MGI Symbol;Acc:MGI:101787]	"GO:0016020,GO:0055114,GO:0016021,GO:0016491,GO:0005739,GO:0005743,GO:0070469,GO:0030425,GO:0043025,GO:0031966,GO:0008137,GO:0005747,GO:0009060,GO:0033194,GO:0003954,GO:0014070,GO:0042493"	membrane|oxidation-reduction process|integral component of membrane|oxidoreductase activity|mitochondrion|mitochondrial inner membrane|respirasome|dendrite|neuronal cell body|mitochondrial membrane|NADH dehydrogenase (ubiquinone) activity|mitochondrial respiratory chain complex I|aerobic respiration|response to hydroperoxide|NADH dehydrogenase activity|response to organic cyclic compound|response to drug	--	--
ENSMUSG00000064360	mt-Nd3	3.52E-68	1.607219543	0.644	0.327	1.14E-63	6	1.969	protein_coding	mitochondrially encoded NADH dehydrogenase 3 [Source:MGI Symbol;Acc:MGI:102499]	"GO:0055114,GO:0008137,GO:0016020,GO:0016021,GO:0016491,GO:0005739,GO:0009725,GO:0070469,GO:0006979,GO:0031966,GO:0005747,GO:0071385,GO:0009642"	oxidation-reduction process|NADH dehydrogenase (ubiquinone) activity|membrane|integral component of membrane|oxidoreductase activity|mitochondrion|response to hormone|respirasome|response to oxidative stress|mitochondrial membrane|mitochondrial respiratory chain complex I|cellular response to glucocorticoid stimulus|response to light intensity	--	--
ENSMUSG00000064367	mt-Nd5	9.36E-44	1.578685991	0.546	0.311	3.02E-39	6	1.756	protein_coding	mitochondrially encoded NADH dehydrogenase 5 [Source:MGI Symbol;Acc:MGI:102496]	"GO:0055114,GO:0008137,GO:0042773,GO:0016020,GO:0016021,GO:0016491,GO:0043005,GO:0005739,GO:0005743,GO:0070469,GO:0005747,GO:0003954"	oxidation-reduction process|NADH dehydrogenase (ubiquinone) activity|ATP synthesis coupled electron transport|membrane|integral component of membrane|oxidoreductase activity|neuron projection|mitochondrion|mitochondrial inner membrane|respirasome|mitochondrial respiratory chain complex I|NADH dehydrogenase activity	--	--
ENSMUSG00000065947	mt-Nd4l	1.22E-34	1.376101753	0.406	0.197	3.93E-30	6	2.061	protein_coding	mitochondrially encoded NADH dehydrogenase 4L [Source:MGI Symbol;Acc:MGI:102497]	"GO:0055114,GO:0042773,GO:0016651,GO:0016020,GO:0016021,GO:0016491,GO:0005739,GO:0070469,GO:0031966,GO:0008137,GO:0005747,GO:0030964"	"oxidation-reduction process|ATP synthesis coupled electron transport|oxidoreductase activity, acting on NAD(P)H|membrane|integral component of membrane|oxidoreductase activity|mitochondrion|respirasome|mitochondrial membrane|NADH dehydrogenase (ubiquinone) activity|mitochondrial respiratory chain complex I|NADH dehydrogenase complex"	--	--
ENSMUSG00000064356	mt-Atp8	2.58E-14	0.934291359	0.272	0.153	8.32E-10	6	1.778	protein_coding	mitochondrially encoded ATP synthase 8 [Source:MGI Symbol;Acc:MGI:99926]	"GO:0015986,GO:0015078,GO:0000276,GO:0016020,GO:0016021,GO:0016787,GO:0016887,GO:0006811,GO:0016491,GO:0055114,GO:0005739,GO:0031966,GO:0006754,GO:0045263,GO:0005753"	"ATP synthesis coupled proton transport|proton transmembrane transporter activity|mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|membrane|integral component of membrane|hydrolase activity|ATPase activity|ion transport|oxidoreductase activity|oxidation-reduction process|mitochondrion|mitochondrial membrane|ATP biosynthetic process|proton-transporting ATP synthase complex, coupling factor F(o)|mitochondrial proton-transporting ATP synthase complex"	--	--
ENSMUSG00000076498	Trbc2	0	3.487221577	0.892	0.003	0	7	297.333	TR_C_gene	"T cell receptor beta, constant 2 [Source:MGI Symbol;Acc:MGI:4835227]"	"GO:0016020,GO:0016021,GO:0003823,GO:0034987,GO:0006910,GO:0006911,GO:0006958,GO:0042742,GO:0045087,GO:0050853,GO:0050871,GO:0009897,GO:0042571"	"membrane|integral component of membrane|antigen binding|immunoglobulin receptor binding|phagocytosis, recognition|phagocytosis, engulfment|complement activation, classical pathway|defense response to bacterium|innate immune response|B cell receptor signaling pathway|positive regulation of B cell activation|external side of plasma membrane|immunoglobulin complex, circulating"	--	--
ENSMUSG00000026009	Icos	0	2.655362588	0.672	0.002	0	7	336	protein_coding	inducible T cell co-stimulator [Source:MGI Symbol;Acc:MGI:1858745]	"GO:0031295,GO:0016020,GO:0016021,GO:0009897,GO:0005515,GO:0098609,GO:0005887,GO:0002517"	T cell costimulation|membrane|integral component of membrane|external side of plasma membrane|protein binding|cell-cell adhesion|integral component of plasma membrane|T cell tolerance induction	"mmu04514,mmu04660,mmu04672,mmu05340"	Cell adhesion molecules (CAMs)|T cell receptor signaling pathway|Intestinal immune network for IgA production|Primary immunodeficiency
ENSMUSG00000048521	Cxcr6	0	2.326693373	0.522	0.002	0	7	261	protein_coding	chemokine (C-X-C motif) receptor 6 [Source:MGI Symbol;Acc:MGI:1934582]	"GO:0007186,GO:0016021,GO:0004930,GO:0016494,GO:0006935,GO:0006954,GO:0004950,GO:0015026,GO:0016020,GO:0009897,GO:0006955,GO:0005886,GO:0019722,GO:0007165,GO:0070098,GO:0007204,GO:0016493,GO:0019956,GO:0019957,GO:0060326,GO:0019958"	G protein-coupled receptor signaling pathway|integral component of membrane|G protein-coupled receptor activity|C-X-C chemokine receptor activity|chemotaxis|inflammatory response|chemokine receptor activity|coreceptor activity|membrane|external side of plasma membrane|immune response|plasma membrane|calcium-mediated signaling|signal transduction|chemokine-mediated signaling pathway|positive regulation of cytosolic calcium ion concentration|C-C chemokine receptor activity|chemokine binding|C-C chemokine binding|cell chemotaxis|C-X-C chemokine binding	"mmu04060,mmu04062"	Cytokine-cytokine receptor interaction|Chemokine signaling pathway
ENSMUSG00000032093	Cd3e	0	2.304125361	0.794	0.002	0	7	397	protein_coding	"CD3 antigen, epsilon polypeptide [Source:MGI Symbol;Acc:MGI:88332]"	"GO:0016020,GO:0007166,GO:0004888,GO:0001954,GO:0005886,GO:0016021,GO:0001772,GO:0009897,GO:0005515,GO:0051260,GO:0042803,GO:0046982,GO:0005911,GO:0010628,GO:0002376,GO:0010629,GO:0007584,GO:0050731,GO:0032729,GO:0002250,GO:0050852,GO:0017124,GO:0033077,GO:0042102,GO:0042101,GO:0032753,GO:0097190,GO:0044297,GO:0050870,GO:0050850,GO:0031295,GO:0033634,GO:0045879,GO:0046641,GO:0045086,GO:0030217,GO:0045059,GO:0042105,GO:0045060,GO:0002669,GO:0046649,GO:0016358,GO:0021549,GO:0043197"	membrane|cell surface receptor signaling pathway|transmembrane signaling receptor activity|positive regulation of cell-matrix adhesion|plasma membrane|integral component of membrane|immunological synapse|external side of plasma membrane|protein binding|protein homooligomerization|protein homodimerization activity|protein heterodimerization activity|cell-cell junction|positive regulation of gene expression|immune system process|negative regulation of gene expression|response to nutrient|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of interferon-gamma production|adaptive immune response|T cell receptor signaling pathway|SH3 domain binding|T cell differentiation in thymus|positive regulation of T cell proliferation|T cell receptor complex|positive regulation of interleukin-4 production|apoptotic signaling pathway|cell body|positive regulation of T cell activation|positive regulation of calcium-mediated signaling|T cell costimulation|positive regulation of cell-cell adhesion mediated by integrin|negative regulation of smoothened signaling pathway|positive regulation of alpha-beta T cell proliferation|positive regulation of interleukin-2 biosynthetic process|T cell differentiation|positive thymic T cell selection|alpha-beta T cell receptor complex|negative thymic T cell selection|positive regulation of T cell anergy|lymphocyte activation|dendrite development|cerebellum development|dendritic spine	"mmu04640,mmu04660,mmu04658,mmu04659,mmu05340,mmu05166,mmu05162,mmu05142"	Hematopoietic cell lineage|T cell receptor signaling pathway|Th1 and Th2 cell differentiation|Th17 cell differentiation|Primary immunodeficiency|HTLV-I infection|Measles|Chagas disease (American trypanosomiasis)
ENSMUSG00000056290	Ms4a4b	0	1.77225737	0.456	0.002	0	7	228	protein_coding	"membrane-spanning 4-domains, subfamily A, member 4B [Source:MGI Symbol;Acc:MGI:1913083]"	"GO:0016021,GO:0016020,GO:0005887"	integral component of membrane|membrane|integral component of plasma membrane	--	--
ENSMUSG00000057058	Skap1	0	1.461698343	0.522	0.001	0	7	522	protein_coding	src family associated phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:1925723]	"GO:0005515,GO:0016020,GO:0001772,GO:0005886,GO:0005634,GO:0005829,GO:0005737,GO:0042803,GO:0045944,GO:0005911,GO:0045893,GO:0002376,GO:0016477,GO:0044877,GO:0019901,GO:0001954,GO:0072659,GO:0071364,GO:0001726,GO:0002250,GO:0019903,GO:0050852,GO:0000226,GO:0034116,GO:0051010,GO:0035371,GO:0045785,GO:0044853,GO:0042169,GO:0042101,GO:1903039,GO:0033625,GO:0033634,GO:0002821,GO:0032991"	"protein binding|membrane|immunological synapse|plasma membrane|nucleus|cytosol|cytoplasm|protein homodimerization activity|positive regulation of transcription by RNA polymerase II|cell-cell junction|positive regulation of transcription, DNA-templated|immune system process|cell migration|protein-containing complex binding|protein kinase binding|positive regulation of cell-matrix adhesion|protein localization to plasma membrane|cellular response to epidermal growth factor stimulus|ruffle|adaptive immune response|protein phosphatase binding|T cell receptor signaling pathway|microtubule cytoskeleton organization|positive regulation of heterotypic cell-cell adhesion|microtubule plus-end binding|microtubule plus-end|positive regulation of cell adhesion|plasma membrane raft|SH2 domain binding|T cell receptor complex|positive regulation of leukocyte cell-cell adhesion|positive regulation of integrin activation|positive regulation of cell-cell adhesion mediated by integrin|positive regulation of adaptive immune response|protein-containing complex"	mmu04015	Rap1 signaling pathway
ENSMUSG00000022015	Tnfsf11	0	1.369850263	0.265	0.001	0	7	265	protein_coding	"tumor necrosis factor (ligand) superfamily, member 11 [Source:MGI Symbol;Acc:MGI:1100089]"	"GO:0005515,GO:0016020,GO:0006955,GO:0005164,GO:0016021,GO:0005886,GO:0005737,GO:0042802,GO:0007275,GO:0045944,GO:0005125,GO:0005576,GO:0005615,GO:0010628,GO:0030154,GO:0001503,GO:0055074,GO:0051897,GO:0019221,GO:0043123,GO:0051092,GO:1990830,GO:0002158,GO:0030316,GO:0044691,GO:0045453,GO:0060348,GO:0046330,GO:0009887,GO:0043406,GO:0019722,GO:0002548,GO:0034112,GO:0045670,GO:0060749,GO:0033598,GO:0036035,GO:0038001,GO:0045672,GO:0045780,GO:0048535,GO:0050870,GO:0071847,GO:0071848,GO:1902533,GO:1904616,GO:2001206,GO:0032813,GO:0007257,GO:0033209,GO:0042327,GO:0051091,GO:0051466,GO:0070371,GO:0071812"	protein binding|membrane|immune response|tumor necrosis factor receptor binding|integral component of membrane|plasma membrane|cytoplasm|identical protein binding|multicellular organism development|positive regulation of transcription by RNA polymerase II|cytokine activity|extracellular region|extracellular space|positive regulation of gene expression|cell differentiation|ossification|calcium ion homeostasis|positive regulation of protein kinase B signaling|cytokine-mediated signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of NF-kappaB transcription factor activity|cellular response to leukemia inhibitory factor|osteoclast proliferation|osteoclast differentiation|tooth eruption|bone resorption|bone development|positive regulation of JNK cascade|animal organ morphogenesis|positive regulation of MAP kinase activity|calcium-mediated signaling|monocyte chemotaxis|positive regulation of homotypic cell-cell adhesion|regulation of osteoclast differentiation|mammary gland alveolus development|mammary gland epithelial cell proliferation|osteoclast development|paracrine signaling|positive regulation of osteoclast differentiation|positive regulation of bone resorption|lymph node development|positive regulation of T cell activation|TNFSF11-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling|positive regulation of intracellular signal transduction|regulation of actin binding|positive regulation of osteoclast development|tumor necrosis factor receptor superfamily binding|activation of JUN kinase activity|tumor necrosis factor-mediated signaling pathway|positive regulation of phosphorylation|positive regulation of DNA-binding transcription factor activity|positive regulation of corticotropin-releasing hormone secretion|ERK1 and ERK2 cascade|positive regulation of fever generation by positive regulation of prostaglandin secretion	"mmu04064,mmu04060,mmu04917,mmu04380,mmu05224,mmu05323"	NF-kappa B signaling pathway|Cytokine-cytokine receptor interaction|Prolactin signaling pathway|Osteoclast differentiation|Breast cancer|Rheumatoid arthritis
ENSMUSG00000026117	Zap70	0	1.091783197	0.4	0.001	0	7	400	protein_coding	zeta-chain (TCR) associated protein kinase [Source:MGI Symbol;Acc:MGI:99613]	"GO:0005524,GO:0005737,GO:0006468,GO:0035556,GO:0004672,GO:0004713,GO:0004715,GO:0016020,GO:0016740,GO:0005886,GO:0005829,GO:0005515,GO:0000166,GO:0016301,GO:0016310,GO:0005911,GO:0002376,GO:0001784,GO:0045121,GO:0002250,GO:0050852,GO:0001772,GO:0045059,GO:0045582,GO:0046777,GO:0045061,GO:0046638,GO:0006955,GO:0050850,GO:0018108,GO:0046641,GO:0042101,GO:0045060,GO:0043366"	ATP binding|cytoplasm|protein phosphorylation|intracellular signal transduction|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|membrane|transferase activity|plasma membrane|cytosol|protein binding|nucleotide binding|kinase activity|phosphorylation|cell-cell junction|immune system process|phosphotyrosine residue binding|membrane raft|adaptive immune response|T cell receptor signaling pathway|immunological synapse|positive thymic T cell selection|positive regulation of T cell differentiation|protein autophosphorylation|thymic T cell selection|positive regulation of alpha-beta T cell differentiation|immune response|positive regulation of calcium-mediated signaling|peptidyl-tyrosine phosphorylation|positive regulation of alpha-beta T cell proliferation|T cell receptor complex|negative thymic T cell selection|beta selection	"mmu04014,mmu04064,mmu04650,mmu04660,mmu04658,mmu04659,mmu05340"	Ras signaling pathway|NF-kappa B signaling pathway|Natural killer cell mediated cytotoxicity|T cell receptor signaling pathway|Th1 and Th2 cell differentiation|Th17 cell differentiation|Primary immunodeficiency
ENSMUSG00000024910	Ctsw	0	1.07244567	0.257	0.001	0	7	257	protein_coding	cathepsin W [Source:MGI Symbol;Acc:MGI:1338045]	"GO:0006508,GO:0008234,GO:0005615,GO:0016787,GO:0008233,GO:0005783,GO:0004197,GO:0051603,GO:0005764"	proteolysis|cysteine-type peptidase activity|extracellular space|hydrolase activity|peptidase activity|endoplasmic reticulum|cysteine-type endopeptidase activity|proteolysis involved in cellular protein catabolic process|lysosome	"mmu04142,mmu04210"	Lysosome|Apoptosis
ENSMUSG00000026285	Pdcd1	0	0.970280079	0.27	0	0	7	Inf	protein_coding	programmed cell death 1 [Source:MGI Symbol;Acc:MGI:104879]	"GO:0016020,GO:0016021,GO:0009897,GO:0005886,GO:0005515,GO:0002376,GO:0006915,GO:0043066,GO:0043065,GO:0002250,GO:0070234,GO:0002644,GO:0050777"	membrane|integral component of membrane|external side of plasma membrane|plasma membrane|protein binding|immune system process|apoptotic process|negative regulation of apoptotic process|positive regulation of apoptotic process|adaptive immune response|positive regulation of T cell apoptotic process|negative regulation of tolerance induction|negative regulation of immune response	"mmu04514,mmu04660"	Cell adhesion molecules (CAMs)|T cell receptor signaling pathway
ENSMUSG00000052212	Cd177	0	3.051424429	0.892	0.041	0	8	21.756	protein_coding	CD177 antigen [Source:MGI Symbol;Acc:MGI:1916141]	"GO:0016020,GO:0016021,GO:0005886,GO:0007155,GO:0002376,GO:0045087,GO:0005178,GO:0030667,GO:0045217,GO:0002020,GO:0034394,GO:0048306,GO:0044853,GO:0007159,GO:0032930,GO:2001044,GO:0098742,GO:0030100,GO:0070821,GO:0072672,GO:0043315"	membrane|integral component of membrane|plasma membrane|cell adhesion|immune system process|innate immune response|integrin binding|secretory granule membrane|cell-cell junction maintenance|protease binding|protein localization to cell surface|calcium-dependent protein binding|plasma membrane raft|leukocyte cell-cell adhesion|positive regulation of superoxide anion generation|regulation of integrin-mediated signaling pathway|cell-cell adhesion via plasma-membrane adhesion molecules|regulation of endocytosis|tertiary granule membrane|neutrophil extravasation|positive regulation of neutrophil degranulation	--	--
ENSMUSG00000025236	Adpgk	0	1.78945873	0.743	0.031	0	8	23.968	protein_coding	ADP-dependent glucokinase [Source:MGI Symbol;Acc:MGI:1919391]	"GO:0005975,GO:0016773,GO:0016310,GO:0043843,GO:0006006,GO:0005783"	"carbohydrate metabolic process|phosphotransferase activity, alcohol group as acceptor|phosphorylation|ADP-specific glucokinase activity|glucose metabolic process|endoplasmic reticulum"	mmu00010	Glycolysis / Gluconeogenesis
ENSMUSG00000067613	Krt83	0	1.699817963	0.553	0.022	0	8	25.136	protein_coding	keratin 83 [Source:MGI Symbol;Acc:MGI:3690448]	"GO:0045095,GO:0003674,GO:0005882,GO:0007568,GO:0042633"	keratin filament|molecular_function|intermediate filament|aging|hair cycle	--	--
ENSMUSG00000000157	Itgb2l	0	1.238683884	0.593	0.008	0	8	74.125	protein_coding	integrin beta 2-like [Source:MGI Symbol;Acc:MGI:1277979]	"GO:0007155,GO:0008305,GO:0038023,GO:0007160,GO:0007229,GO:0016020,GO:0016021,GO:0005886,GO:0030141,GO:0006954,GO:0005178,GO:0016477,GO:0033627,GO:0001540"	cell adhesion|integrin complex|signaling receptor activity|cell-matrix adhesion|integrin-mediated signaling pathway|membrane|integral component of membrane|plasma membrane|secretory granule|inflammatory response|integrin binding|cell migration|cell adhesion mediated by integrin|amyloid-beta binding	"mmu04015,mmu04390,mmu04514,mmu04145,mmu04810,mmu04610,mmu04650,mmu04670,mmu05323,mmu05416,mmu05133,mmu05134,mmu05150,mmu05152,mmu05166,mmu05146,mmu05144,mmu05140"	Rap1 signaling pathway|Hippo signaling pathway|Cell adhesion molecules (CAMs)|Phagosome|Regulation of actin cytoskeleton|Complement and coagulation cascades|Natural killer cell mediated cytotoxicity|Leukocyte transendothelial migration|Rheumatoid arthritis|Viral myocarditis|Pertussis|Legionellosis|Staphylococcus aureus infection|Tuberculosis|HTLV-I infection|Amoebiasis|Malaria|Leishmaniasis
ENSMUSG00000054169	Ceacam10	0	1.196605756	0.54	0.02	0	8	27	protein_coding	carcinoembryonic antigen-related cell adhesion molecule 10 [Source:MGI Symbol;Acc:MGI:1347248]	--	--	--	--
ENSMUSG00000031377	Bmx	0	0.949572585	0.511	0.021	0	8	24.333	protein_coding	BMX non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:1101778]	"GO:0005524,GO:0006468,GO:0035556,GO:0004672,GO:0004713,GO:0004715,GO:0016740,GO:0000166,GO:0016301,GO:0016310,GO:0018108,GO:0007165,GO:0046777,GO:0005654,GO:0005886,GO:0032587,GO:0046872,GO:0005737,GO:0007155,GO:0006915"	ATP binding|protein phosphorylation|intracellular signal transduction|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|transferase activity|nucleotide binding|kinase activity|phosphorylation|peptidyl-tyrosine phosphorylation|signal transduction|protein autophosphorylation|nucleoplasm|plasma membrane|ruffle membrane|metal ion binding|cytoplasm|cell adhesion|apoptotic process	--	--
ENSMUSG00000025701	Alox5	0	0.881690323	0.516	0.023	0	8	22.435	protein_coding	arachidonate 5-lipoxygenase [Source:MGI Symbol;Acc:MGI:87999]	"GO:0046872,GO:0005515,GO:0055114,GO:0016702,GO:0005506,GO:0016020,GO:0005634,GO:0005654,GO:0005829,GO:0005737,GO:0016491,GO:0042383,GO:0031965,GO:0019370,GO:0006954,GO:0051213,GO:0030425,GO:0006691,GO:0005635,GO:0019233,GO:0016363,GO:0045907,GO:0002526,GO:0005641,GO:0002540,GO:0004051,GO:1904960"	"metal ion binding|protein binding|oxidation-reduction process|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|iron ion binding|membrane|nucleus|nucleoplasm|cytosol|cytoplasm|oxidoreductase activity|sarcolemma|nuclear membrane|leukotriene biosynthetic process|inflammatory response|dioxygenase activity|dendrite|leukotriene metabolic process|nuclear envelope|sensory perception of pain|nuclear matrix|positive regulation of vasoconstriction|acute inflammatory response|nuclear envelope lumen|leukotriene production involved in inflammatory response|arachidonate 5-lipoxygenase activity|positive regulation of cytochrome-c oxidase activity"	"mmu00590,mmu04664,mmu04913,mmu04726,mmu05145"	Arachidonic acid metabolism|Fc epsilon RI signaling pathway|Ovarian Steroidogenesis|Serotonergic synapse|Toxoplasmosis
ENSMUSG00000019066	Rab3d	0	0.693470785	0.397	0.015	0	8	26.467	protein_coding	"RAB3D, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97844]"	"GO:0005525,GO:0003924,GO:0016020,GO:0005886,GO:0005515,GO:0015031,GO:0000166,GO:0005739,GO:0005768,GO:0030133,GO:0030742,GO:0005881,GO:0099503,GO:0006886,GO:0045453,GO:0006887,GO:0072659,GO:0031982,GO:1903307,GO:0009306,GO:0032482,GO:0008021,GO:0017157,GO:0042588,GO:0031489,GO:0018125,GO:0006904"	GTP binding|GTPase activity|membrane|plasma membrane|protein binding|protein transport|nucleotide binding|mitochondrion|endosome|transport vesicle|GTP-dependent protein binding|cytoplasmic microtubule|secretory vesicle|intracellular protein transport|bone resorption|exocytosis|protein localization to plasma membrane|vesicle|positive regulation of regulated secretory pathway|protein secretion|Rab protein signal transduction|synaptic vesicle|regulation of exocytosis|zymogen granule|myosin V binding|peptidyl-cysteine methylation|vesicle docking involved in exocytosis	mmu04972	Pancreatic secretion
ENSMUSG00000072875	Gpr27	0	0.527686337	0.31	0.01	0	8	31	protein_coding	G protein-coupled receptor 27 [Source:MGI Symbol;Acc:MGI:1202299]	"GO:0007186,GO:0016021,GO:0004930,GO:0016020,GO:0005886,GO:0007165,GO:0035774,GO:1900738"	G protein-coupled receptor signaling pathway|integral component of membrane|G protein-coupled receptor activity|membrane|plasma membrane|signal transduction|positive regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	--	--
ENSMUSG00000100147	1700047M11Rik	0	0.485356711	0.294	0.007	0	8	42	lncRNA	RIKEN cDNA 1700047M11 gene [Source:MGI Symbol;Acc:MGI:1914580]	--	--	--	--
ENSMUSG00000057092	Fxyd3	0	3.083728908	0.605	0.044	0	9	13.75	protein_coding	FXYD domain-containing ion transport regulator 3 [Source:MGI Symbol;Acc:MGI:107497]	"GO:0016020,GO:0099106,GO:0043269,GO:0016021,GO:0005886,GO:0005515,GO:0006811,GO:0006813,GO:0006814,GO:0005789,GO:0051117,GO:0050790,GO:0017080,GO:2000649"	membrane|ion channel regulator activity|regulation of ion transport|integral component of membrane|plasma membrane|protein binding|ion transport|potassium ion transport|sodium ion transport|endoplasmic reticulum membrane|ATPase binding|regulation of catalytic activity|sodium channel regulator activity|regulation of sodium ion transmembrane transporter activity	--	--
ENSMUSG00000053522	Lgals7	2.11E-226	4.555910814	0.432	0.042	6.81E-222	9	10.286	protein_coding	"lectin, galactose binding, soluble 7 [Source:MGI Symbol;Acc:MGI:1316742]"	"GO:0005615,GO:0030246,GO:0007157"	extracellular space|carbohydrate binding|heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	--	--
ENSMUSG00000042808	Gpx2	3.77E-217	1.862558632	0.255	0.012	1.22E-212	9	21.25	protein_coding	glutathione peroxidase 2 [Source:MGI Symbol;Acc:MGI:106609]	"GO:0055114,GO:0004602,GO:0006979,GO:0016491,GO:0098869,GO:0004601"	oxidation-reduction process|glutathione peroxidase activity|response to oxidative stress|oxidoreductase activity|cellular oxidant detoxification|peroxidase activity	"mmu00590,mmu00480,mmu04918"	Arachidonic acid metabolism|Glutathione metabolism|Thyroid hormone synthesis
ENSMUSG00000035557	Krt17	1.15E-215	3.730652031	0.371	0.031	3.70E-211	9	11.968	protein_coding	keratin 17 [Source:MGI Symbol;Acc:MGI:96691]	"GO:0005198,GO:0071944,GO:0005737,GO:0005515,GO:0005882,GO:0045109,GO:0007165,GO:0042289,GO:0045111,GO:0045727,GO:0051798,GO:0031424,GO:0030307,GO:0002009,GO:0031069,GO:0032395"	structural molecule activity|cell periphery|cytoplasm|protein binding|intermediate filament|intermediate filament organization|signal transduction|MHC class II protein binding|intermediate filament cytoskeleton|positive regulation of translation|positive regulation of hair follicle development|keratinization|positive regulation of cell growth|morphogenesis of an epithelium|hair follicle morphogenesis|MHC class II receptor activity	mmu04915	Estrogen signaling pathway
ENSMUSG00000045545	Krt14	1.82E-199	3.90317822	0.483	0.063	5.89E-195	9	7.667	protein_coding	keratin 14 [Source:MGI Symbol;Acc:MGI:96688]	"GO:0005198,GO:0071944,GO:0005634,GO:0005737,GO:0005515,GO:0005882,GO:0045095,GO:0007568,GO:0042633,GO:0030855,GO:0045110,GO:1990254,GO:0010043,GO:0010212,GO:0045178"	structural molecule activity|cell periphery|nucleus|cytoplasm|protein binding|intermediate filament|keratin filament|aging|hair cycle|epithelial cell differentiation|intermediate filament bundle assembly|keratin filament binding|response to zinc ion|response to ionizing radiation|basal part of cell	mmu04915	Estrogen signaling pathway
ENSMUSG00000061527	Krt5	1.46E-194	2.797737609	0.295	0.021	4.71E-190	9	14.048	protein_coding	keratin 5 [Source:MGI Symbol;Acc:MGI:96702]	"GO:0045095,GO:0005515,GO:0005737,GO:0005886,GO:0005882,GO:0005739,GO:0097110"	keratin filament|protein binding|cytoplasm|plasma membrane|intermediate filament|mitochondrion|scaffold protein binding	--	--
ENSMUSG00000045394	Epcam	4.08E-188	2.045385455	0.316	0.025	1.32E-183	9	12.64	protein_coding	epithelial cell adhesion molecule [Source:MGI Symbol;Acc:MGI:106653]	"GO:0016020,GO:0016021,GO:0005886,GO:0009986,GO:0030054,GO:0045944,GO:0016324,GO:0016328,GO:0044877,GO:0016323,GO:0005923,GO:0043066,GO:0008284,GO:2000147,GO:2000648,GO:0001657,GO:0023019,GO:0048863,GO:2000048,GO:0098742,GO:0098641"	membrane|integral component of membrane|plasma membrane|cell surface|cell junction|positive regulation of transcription by RNA polymerase II|apical plasma membrane|lateral plasma membrane|protein-containing complex binding|basolateral plasma membrane|bicellular tight junction|negative regulation of apoptotic process|positive regulation of cell population proliferation|positive regulation of cell motility|positive regulation of stem cell proliferation|ureteric bud development|signal transduction involved in regulation of gene expression|stem cell differentiation|negative regulation of cell-cell adhesion mediated by cadherin|cell-cell adhesion via plasma-membrane adhesion molecules|cadherin binding involved in cell-cell adhesion	--	--
ENSMUSG00000044217	Aqp5	1.85E-179	2.184937281	0.258	0.017	5.97E-175	9	15.176	protein_coding	aquaporin 5 [Source:MGI Symbol;Acc:MGI:106215]	"GO:0016020,GO:0055085,GO:0015267,GO:0016021,GO:0005515,GO:0030659,GO:0031410,GO:0016324,GO:0042802,GO:0005886,GO:0048593,GO:0005783,GO:0005887,GO:0005902,GO:0051289,GO:0009925,GO:0006833,GO:0015250,GO:0046541,GO:0015670,GO:0071476,GO:0030157,GO:0042476"	membrane|transmembrane transport|channel activity|integral component of membrane|protein binding|cytoplasmic vesicle membrane|cytoplasmic vesicle|apical plasma membrane|identical protein binding|plasma membrane|camera-type eye morphogenesis|endoplasmic reticulum|integral component of plasma membrane|microvillus|protein homotetramerization|basal plasma membrane|water transport|water channel activity|saliva secretion|carbon dioxide transport|cellular hypotonic response|pancreatic juice secretion|odontogenesis	mmu04970	Salivary secretion
ENSMUSG00000019851	Perp	2.93E-167	1.86979942	0.261	0.019	9.45E-163	9	13.737	protein_coding	"PERP, TP53 apoptosis effector [Source:MGI Symbol;Acc:MGI:1929938]"	"GO:0016021,GO:0016020,GO:0005886,GO:0005794,GO:0030054,GO:0005887,GO:0007155,GO:0005739,GO:0006915,GO:0097186,GO:0045862,GO:0007219,GO:0002934,GO:0030057,GO:0097202,GO:0072332,GO:0034113"	integral component of membrane|membrane|plasma membrane|Golgi apparatus|cell junction|integral component of plasma membrane|cell adhesion|mitochondrion|apoptotic process|amelogenesis|positive regulation of proteolysis|Notch signaling pathway|desmosome organization|desmosome|activation of cysteine-type endopeptidase activity|intrinsic apoptotic signaling pathway by p53 class mediator|heterotypic cell-cell adhesion	mmu04115	p53 signaling pathway
ENSMUSG00000034634	Ly6d	2.77E-153	2.572961749	0.337	0.036	8.93E-149	9	9.361	protein_coding	"lymphocyte antigen 6 complex, locus D [Source:MGI Symbol;Acc:MGI:96881]"	"GO:0016020,GO:0005886,GO:0009986,GO:0031225,GO:0035634,GO:0030098"	membrane|plasma membrane|cell surface|anchored component of membrane|response to stilbenoid|lymphocyte differentiation	--	--
ENSMUSG00000071005	Ccl19	0	2.642610191	0.273	0.008	0	10	34.125	protein_coding	"C-C motif chemokine 19-like, partial"	"GO:0001768,GO:0001771,GO:0002407,GO:0002408,GO:0002548,GO:0002606,GO:0005615,GO:0005622,GO:0006954,GO:0007186,GO:0007257,GO:0008009,GO:0009897,GO:0010560,GO:0030593,GO:0031295,GO:0031732,GO:0031735,GO:0032735,GO:0032760,GO:0034695,GO:0042102,GO:0042379,GO:0043123,GO:0043547,GO:0043552,GO:0045627,GO:0045807,GO:0045860,GO:0046330,GO:0048020,GO:0048247,GO:0048260,GO:0048469,GO:0050718,GO:0050921,GO:0051209,GO:0051897,GO:0060491,GO:0070098,GO:0070374,GO:0071346,GO:0071347,GO:0071356,GO:0071731,GO:0072610,GO:0090023,GO:0097029,GO:0098586,GO:1901224,GO:2000147,GO:2000549,GO:2000669"	establishment of T cell polarity|immunological synapse formation|dendritic cell chemotaxis|myeloid dendritic cell chemotaxis|monocyte chemotaxis|positive regulation of dendritic cell antigen processing and presentation|extracellular space|intracellular|inflammatory response|G protein-coupled receptor signaling pathway|activation of JUN kinase activity|chemokine activity|external side of plasma membrane|positive regulation of glycoprotein biosynthetic process|neutrophil chemotaxis|T cell costimulation|CCR7 chemokine receptor binding|CCR10 chemokine receptor binding|positive regulation of interleukin-12 production|positive regulation of tumor necrosis factor production|response to prostaglandin E|positive regulation of T cell proliferation|chemokine receptor binding|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of GTPase activity|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of T-helper 1 cell differentiation|positive regulation of endocytosis|positive regulation of protein kinase activity|positive regulation of JNK cascade|CCR chemokine receptor binding|lymphocyte chemotaxis|positive regulation of receptor-mediated endocytosis|cell maturation|positive regulation of interleukin-1 beta secretion|positive regulation of chemotaxis|release of sequestered calcium ion into cytosol|positive regulation of protein kinase B signaling|regulation of cell projection assembly|chemokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|cellular response to interferon-gamma|cellular response to interleukin-1|cellular response to tumor necrosis factor|response to nitric oxide|interleukin-12 secretion|positive regulation of neutrophil chemotaxis|mature conventional dendritic cell differentiation|cellular response to virus|positive regulation of NIK/NF-kappaB signaling|positive regulation of cell motility|positive regulation of dendritic cell dendrite assembly|negative regulation of dendritic cell apoptotic process	--	--
ENSMUSG00000021388	Aspn	0	2.499702988	0.317	0.005	0	10	63.4	protein_coding	asporin [Source:MGI Symbol;Acc:MGI:1913945]	"GO:0005515,GO:0005509,GO:0005518,GO:0005576,GO:0031012,GO:0055085,GO:0015288,GO:0046930,GO:0030282,GO:0030512,GO:0031214,GO:0062023,GO:0042995,GO:0030021,GO:0070171"	protein binding|calcium ion binding|collagen binding|extracellular region|extracellular matrix|transmembrane transport|porin activity|pore complex|bone mineralization|negative regulation of transforming growth factor beta receptor signaling pathway|biomineral tissue development|collagen-containing extracellular matrix|cell projection|extracellular matrix structural constituent conferring compression resistance|negative regulation of tooth mineralization	--	--
ENSMUSG00000040280	Ndufa4l2	0	1.860472354	0.266	0.006	0	10	44.333	protein_coding	"Ndufa4, mitochondrial complex associated like 2 [Source:MGI Symbol;Acc:MGI:3039567]"	"GO:0008150,GO:0022900,GO:1902600,GO:0004129,GO:0005751"	biological_process|electron transport chain|proton transmembrane transport|cytochrome-c oxidase activity|mitochondrial respiratory chain complex IV	"mmu00190,mmu04723,mmu04714,mmu05010,mmu05012,mmu05016,mmu04932"	Oxidative phosphorylation|Retrograde endocannabinoid signaling|Thermogenesis|Alzheimer's disease|Parkinson's disease|Huntington's disease|Non-alcoholic fatty liver disease (NAFLD)
ENSMUSG00000029718	Pcolce	0	1.722414365	0.364	0.01	0	10	36.4	protein_coding	procollagen C-endopeptidase enhancer protein [Source:MGI Symbol;Acc:MGI:105099]	"GO:0005515,GO:0005615,GO:0008201,GO:0016504,GO:0005518,GO:0005576,GO:0010952,GO:0005581,GO:1990830,GO:0006508"	protein binding|extracellular space|heparin binding|peptidase activator activity|collagen binding|extracellular region|positive regulation of peptidase activity|collagen trimer|cellular response to leukemia inhibitory factor|proteolysis	--	--
ENSMUSG00000024620	Pdgfrb	0	1.555594917	0.282	0.006	0	10	47	protein_coding	"platelet derived growth factor receptor, beta polypeptide [Source:MGI Symbol;Acc:MGI:97531]"	"GO:0005524,GO:0006468,GO:0004672,GO:0007169,GO:0004714,GO:0004713,GO:0048008,GO:0005019,GO:0016020,GO:0016021,GO:0016740,GO:0005886,GO:0000166,GO:0031410,GO:0007275,GO:0016301,GO:0016310,GO:0018108,GO:0006935,GO:0005764,GO:0043202,GO:0035791"	ATP binding|protein phosphorylation|protein kinase activity|transmembrane receptor protein tyrosine kinase signaling pathway|transmembrane receptor protein tyrosine kinase activity|protein tyrosine kinase activity|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor beta-receptor activity|membrane|integral component of membrane|transferase activity|plasma membrane|nucleotide binding|cytoplasmic vesicle|multicellular organism development|kinase activity|phosphorylation|peptidyl-tyrosine phosphorylation|chemotaxis|lysosome|lysosomal lumen|platelet-derived growth factor receptor-beta signaling pathway	"mmu04014,mmu04015,mmu04010,mmu04630,mmu04020,mmu04072,mmu04151,mmu04060,mmu04510,mmu04540,mmu04810,mmu05200,mmu05230,mmu05231,mmu05206,mmu05214,mmu05218,mmu05215,mmu05166,mmu05165,mmu01521"	Ras signaling pathway|Rap1 signaling pathway|MAPK signaling pathway|Jak-STAT signaling pathway|Calcium signaling pathway|Phospholipase D signaling pathway|PI3K-Akt signaling pathway|Cytokine-cytokine receptor interaction|Focal adhesion|Gap junction|Regulation of actin cytoskeleton|Pathways in cancer|Central carbon metabolism in cancer|Choline metabolism in cancer|MicroRNAs in cancer|Glioma|Melanoma|Prostate cancer|HTLV-I infection|Human papillomavirus infection|EGFR tyrosine kinase inhibitor resistance
ENSMUSG00000001119	Col6a1	0	1.546215139	0.292	0.007	0	10	41.714	protein_coding	"collagen, type VI, alpha 1 [Source:MGI Symbol;Acc:MGI:88459]"	"GO:0005615,GO:0032991,GO:0005576,GO:0003429,GO:0031012,GO:0042383,GO:0062023,GO:0007155,GO:0005581,GO:0005518,GO:0030020,GO:0071230,GO:0048407,GO:0035987"	extracellular space|protein-containing complex|extracellular region|growth plate cartilage chondrocyte morphogenesis|extracellular matrix|sarcolemma|collagen-containing extracellular matrix|cell adhesion|collagen trimer|collagen binding|extracellular matrix structural constituent conferring tensile strength|cellular response to amino acid stimulus|platelet-derived growth factor binding|endodermal cell differentiation	"mmu04151,mmu04512,mmu04510,mmu04974,mmu05165"	PI3K-Akt signaling pathway|ECM-receptor interaction|Focal adhesion|Protein digestion and absorption|Human papillomavirus infection
ENSMUSG00000026586	Prrx1	0	1.494355369	0.313	0.005	0	10	62.6	protein_coding	paired related homeobox 1 [Source:MGI Symbol;Acc:MGI:97712]	"GO:0003677,GO:0006355,GO:0043565,GO:0005634,GO:0005654,GO:0005829,GO:0007275,GO:0045944,GO:0000122,GO:0042472,GO:0060021,GO:0003713,GO:0000978,GO:0001227,GO:0048844,GO:0045880,GO:0048704,GO:0048701,GO:0051216,GO:0071837,GO:0030326,GO:0042474,GO:0097150,GO:0002053,GO:0048664,GO:0070570"	"DNA binding|regulation of transcription, DNA-templated|sequence-specific DNA binding|nucleus|nucleoplasm|cytosol|multicellular organism development|positive regulation of transcription by RNA polymerase II|negative regulation of transcription by RNA polymerase II|inner ear morphogenesis|roof of mouth development|transcription coactivator activity|RNA polymerase II proximal promoter sequence-specific DNA binding|DNA-binding transcription repressor activity, RNA polymerase II-specific|artery morphogenesis|positive regulation of smoothened signaling pathway|embryonic skeletal system morphogenesis|embryonic cranial skeleton morphogenesis|cartilage development|HMG box domain binding|embryonic limb morphogenesis|middle ear morphogenesis|neuronal stem cell population maintenance|positive regulation of mesenchymal cell proliferation|neuron fate determination|regulation of neuron projection regeneration"	--	--
ENSMUSG00000020241	Col6a2	0	1.462904021	0.279	0.006	0	10	46.5	protein_coding	"collagen, type VI, alpha 2 [Source:MGI Symbol;Acc:MGI:88460]"	"GO:0005615,GO:0016020,GO:0032991,GO:0005576,GO:0003429,GO:0031012,GO:0042383,GO:0062023,GO:0007155,GO:0005581,GO:0005518,GO:0030020,GO:0009749"	extracellular space|membrane|protein-containing complex|extracellular region|growth plate cartilage chondrocyte morphogenesis|extracellular matrix|sarcolemma|collagen-containing extracellular matrix|cell adhesion|collagen trimer|collagen binding|extracellular matrix structural constituent conferring tensile strength|response to glucose	"mmu04151,mmu04512,mmu04510,mmu04974,mmu05165"	PI3K-Akt signaling pathway|ECM-receptor interaction|Focal adhesion|Protein digestion and absorption|Human papillomavirus infection
ENSMUSG00000048126	Col6a3	0	1.444722706	0.251	0.005	0	10	50.2	protein_coding	"collagen, type VI, alpha 3 [Source:MGI Symbol;Acc:MGI:88461]"	"GO:0005515,GO:0004867,GO:0005615,GO:0003429,GO:0005581,GO:0031012,GO:0042383,GO:0062023,GO:0010951,GO:0030020"	protein binding|serine-type endopeptidase inhibitor activity|extracellular space|growth plate cartilage chondrocyte morphogenesis|collagen trimer|extracellular matrix|sarcolemma|collagen-containing extracellular matrix|negative regulation of endopeptidase activity|extracellular matrix structural constituent conferring tensile strength	"mmu04151,mmu04512,mmu04510,mmu04974,mmu05165"	PI3K-Akt signaling pathway|ECM-receptor interaction|Focal adhesion|Protein digestion and absorption|Human papillomavirus infection
ENSMUSG00000036103	Colec12	0	1.398977795	0.26	0.005	0	10	52	protein_coding	collectin sub-family member 12 [Source:MGI Symbol;Acc:MGI:2152907]	"GO:0016020,GO:0016021,GO:0046872,GO:0030246,GO:0005581,GO:0004888,GO:0062023,GO:0008329,GO:0034138,GO:0006955,GO:0060355,GO:0030169,GO:0006910"	"membrane|integral component of membrane|metal ion binding|carbohydrate binding|collagen trimer|transmembrane signaling receptor activity|collagen-containing extracellular matrix|signaling pattern recognition receptor activity|toll-like receptor 3 signaling pathway|immune response|positive regulation of cell adhesion molecule production|low-density lipoprotein particle binding|phagocytosis, recognition"	mmu04145	Phagosome
ENSMUSG00000056492	Adgrf5	0	2.688527696	0.585	0.005	0	11	117	protein_coding	adhesion G protein-coupled receptor F5 [Source:MGI Symbol;Acc:MGI:2182928]	"GO:0007186,GO:0016021,GO:0004930,GO:0016020,GO:0007166,GO:0004888,GO:0003674,GO:0005886,GO:0009986,GO:0031410,GO:0045177,GO:0042593,GO:0045444,GO:0003094,GO:0043129,GO:0048821,GO:0006112,GO:0019216,GO:0043031,GO:0061626,GO:0071073"	G protein-coupled receptor signaling pathway|integral component of membrane|G protein-coupled receptor activity|membrane|cell surface receptor signaling pathway|transmembrane signaling receptor activity|molecular_function|plasma membrane|cell surface|cytoplasmic vesicle|apical part of cell|glucose homeostasis|fat cell differentiation|glomerular filtration|surfactant homeostasis|erythrocyte development|energy reserve metabolic process|regulation of lipid metabolic process|negative regulation of macrophage activation|pharyngeal arch artery morphogenesis|positive regulation of phospholipid biosynthetic process	--	--
ENSMUSG00000022579	Gpihbp1	0	2.563761811	0.381	0.002	0	11	190.5	protein_coding	GPI-anchored HDL-binding protein 1 [Source:MGI Symbol;Acc:MGI:1915703]	"GO:0042632,GO:0070328,GO:0016020,GO:0005886,GO:0009986,GO:0008289,GO:0030550,GO:2000272,GO:0031225,GO:0046658,GO:0016324,GO:0016323,GO:0006869,GO:0051006,GO:0009897,GO:0008035,GO:0071813,GO:0050821,GO:0034394,GO:0035473,GO:0035478,GO:0140318,GO:0006886,GO:0017038,GO:0045056,GO:0090319,GO:0090321"	cholesterol homeostasis|triglyceride homeostasis|membrane|plasma membrane|cell surface|lipid binding|acetylcholine receptor inhibitor activity|negative regulation of signaling receptor activity|anchored component of membrane|anchored component of plasma membrane|apical plasma membrane|basolateral plasma membrane|lipid transport|positive regulation of lipoprotein lipase activity|external side of plasma membrane|high-density lipoprotein particle binding|lipoprotein particle binding|protein stabilization|protein localization to cell surface|lipase binding|chylomicron binding|protein transporter activity|intracellular protein transport|protein import|transcytosis|positive regulation of chylomicron remodeling|positive regulation of chylomicron remnant clearance	--	--
ENSMUSG00000041134	Cyyr1	0	2.129273026	0.443	0.004	0	11	110.75	protein_coding	cysteine and tyrosine-rich protein 1 [Source:MGI Symbol;Acc:MGI:2152187]	"GO:0016020,GO:0016021,GO:0003674,GO:0008150,GO:0005575"	membrane|integral component of membrane|molecular_function|biological_process|cellular_component	--	--
ENSMUSG00000039167	Adgrl4	0	2.098656709	0.475	0.003	0	11	158.333	protein_coding	adhesion G protein-coupled receptor L4 [Source:MGI Symbol;Acc:MGI:2655562]	"GO:0007186,GO:0016021,GO:0004930,GO:0005509,GO:0007166,GO:0004888,GO:0016020,GO:0005886,GO:0005887,GO:0031410,GO:0007165,GO:0046983,GO:0007189"	G protein-coupled receptor signaling pathway|integral component of membrane|G protein-coupled receptor activity|calcium ion binding|cell surface receptor signaling pathway|transmembrane signaling receptor activity|membrane|plasma membrane|integral component of plasma membrane|cytoplasmic vesicle|signal transduction|protein dimerization activity|adenylate cyclase-activating G protein-coupled receptor signaling pathway	--	--
ENSMUSG00000023959	Clic5	0	1.69320691	0.381	0.003	0	11	127	protein_coding	chloride intracellular channel 5 [Source:MGI Symbol;Acc:MGI:1917912]	"GO:0005515,GO:0006821,GO:0005254,GO:0016020,GO:0016021,GO:0005794,GO:0005886,GO:0005634,GO:0005737,GO:0006811,GO:0015629,GO:0005856,GO:0005244,GO:0034765,GO:0050896,GO:0034220,GO:1902476,GO:0007605,GO:0034707,GO:0007601,GO:0008104,GO:0005815,GO:0005938,GO:0050885,GO:0016324,GO:0002021,GO:0060088,GO:0032421,GO:0032420,GO:0002024"	protein binding|chloride transport|chloride channel activity|membrane|integral component of membrane|Golgi apparatus|plasma membrane|nucleus|cytoplasm|ion transport|actin cytoskeleton|cytoskeleton|voltage-gated ion channel activity|regulation of ion transmembrane transport|response to stimulus|ion transmembrane transport|chloride transmembrane transport|sensory perception of sound|chloride channel complex|visual perception|protein localization|microtubule organizing center|cell cortex|neuromuscular process controlling balance|apical plasma membrane|response to dietary excess|auditory receptor cell stereocilium organization|stereocilium bundle|stereocilium|diet induced thermogenesis	--	--
ENSMUSG00000046916	Myct1	0	1.466345077	0.33	0.002	0	11	165	protein_coding	myc target 1 [Source:MGI Symbol;Acc:MGI:1915882]	"GO:0016020,GO:0016021,GO:0003674,GO:0008150,GO:0005634,GO:0005654,GO:0043231,GO:0031965"	membrane|integral component of membrane|molecular_function|biological_process|nucleus|nucleoplasm|intracellular membrane-bounded organelle|nuclear membrane	--	--
ENSMUSG00000033191	Tie1	0	1.426597533	0.355	0.003	0	11	118.333	protein_coding	tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Source:MGI Symbol;Acc:MGI:99906]	"GO:0005515,GO:0005524,GO:0006468,GO:0004672,GO:0004713,GO:0016020,GO:0016021,GO:0016740,GO:0005886,GO:0005887,GO:0000166,GO:0016301,GO:0016310,GO:0018108,GO:0004714,GO:0001701,GO:0001570,GO:0016525,GO:0001525,GO:0001568,GO:0030336,GO:0043235,GO:0007169,GO:0045766,GO:0032526,GO:0045026"	protein binding|ATP binding|protein phosphorylation|protein kinase activity|protein tyrosine kinase activity|membrane|integral component of membrane|transferase activity|plasma membrane|integral component of plasma membrane|nucleotide binding|kinase activity|phosphorylation|peptidyl-tyrosine phosphorylation|transmembrane receptor protein tyrosine kinase activity|in utero embryonic development|vasculogenesis|negative regulation of angiogenesis|angiogenesis|blood vessel development|negative regulation of cell migration|receptor complex|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of angiogenesis|response to retinoic acid|plasma membrane fusion	--	--
ENSMUSG00000025902	Sox17	0	1.393233726	0.255	0.001	0	11	255	protein_coding	SRY (sex determining region Y)-box 17 [Source:MGI Symbol;Acc:MGI:107543]	"GO:0003151,GO:0003677,GO:0005634,GO:0005515,GO:0016055,GO:0045944,GO:0007283,GO:0001228,GO:0010628,GO:0045893,GO:0000981,GO:0030154,GO:0001570,GO:0045595,GO:0007492,GO:0008134,GO:0043565,GO:0031648,GO:0050821,GO:0006355,GO:0003700,GO:1990830,GO:0044212,GO:0090090,GO:0003713,GO:0030308,GO:0048568,GO:0008013,GO:0001656,GO:0005667,GO:0007369,GO:0030178,GO:0001525,GO:0045995,GO:0045732,GO:0045597,GO:0001947,GO:0001706,GO:0023019,GO:0042074,GO:0042789,GO:0048863,GO:0072091,GO:0060913,GO:0044798,GO:0035050,GO:0021903,GO:0048617,GO:0061009,GO:0003143,GO:0061010,GO:0048866,GO:0060214,GO:0060956,GO:2000035,GO:0072189,GO:0007493,GO:0001828,GO:0003142,GO:0003308,GO:0060807,GO:0061031,GO:2000043"	"outflow tract morphogenesis|DNA binding|nucleus|protein binding|Wnt signaling pathway|positive regulation of transcription by RNA polymerase II|spermatogenesis|DNA-binding transcription activator activity, RNA polymerase II-specific|positive regulation of gene expression|positive regulation of transcription, DNA-templated|DNA-binding transcription factor activity, RNA polymerase II-specific|cell differentiation|vasculogenesis|regulation of cell differentiation|endoderm development|transcription factor binding|sequence-specific DNA binding|protein destabilization|protein stabilization|regulation of transcription, DNA-templated|DNA-binding transcription factor activity|cellular response to leukemia inhibitory factor|transcription regulatory region DNA binding|negative regulation of canonical Wnt signaling pathway|transcription coactivator activity|negative regulation of cell growth|embryonic organ development|beta-catenin binding|metanephros development|transcription factor complex|gastrulation|negative regulation of Wnt signaling pathway|angiogenesis|regulation of embryonic development|positive regulation of protein catabolic process|positive regulation of cell differentiation|heart looping|endoderm formation|signal transduction involved in regulation of gene expression|cell migration involved in gastrulation|mRNA transcription by RNA polymerase II|stem cell differentiation|regulation of stem cell proliferation|cardiac cell fate determination|nuclear transcription factor complex|embryonic heart tube development|rostrocaudal neural tube patterning|embryonic foregut morphogenesis|common bile duct development|embryonic heart tube morphogenesis|gall bladder development|stem cell fate specification|endocardium formation|endocardial cell differentiation|regulation of stem cell division|ureter development|endodermal cell fate determination|inner cell mass cellular morphogenesis|cardiogenic plate morphogenesis|negative regulation of Wnt signaling pathway involved in heart development|regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification|endodermal digestive tract morphogenesis|regulation of cardiac cell fate specification"	mmu04310	Wnt signaling pathway
ENSMUSG00000032125	Robo4	0	1.260062615	0.296	0.001	0	11	296	protein_coding	roundabout guidance receptor 4 [Source:MGI Symbol;Acc:MGI:1921394]	"GO:0005515,GO:0001525"	protein binding|angiogenesis	--	--
ENSMUSG00000052921	Arhgef15	0	1.087774714	0.252	0.001	0	11	252	protein_coding	Rho guanine nucleotide exchange factor (GEF) 15 [Source:MGI Symbol;Acc:MGI:3045246]	"GO:0005089,GO:0035023,GO:0005096,GO:0043547,GO:0005737,GO:0042995,GO:0005085,GO:0030425,GO:0051496,GO:0050790,GO:0061299,GO:2000297"	Rho guanyl-nucleotide exchange factor activity|regulation of Rho protein signal transduction|GTPase activator activity|positive regulation of GTPase activity|cytoplasm|cell projection|guanyl-nucleotide exchange factor activity|dendrite|positive regulation of stress fiber assembly|regulation of catalytic activity|retina vasculature morphogenesis in camera-type eye|negative regulation of synapse maturation	--	--
ENSMUSG00000043924	Ncmap	0	3.859710307	0.755	0.005	0	12	151	protein_coding	noncompact myelin associated protein [Source:MGI Symbol;Acc:MGI:2444888]	"GO:0005887,GO:0019911,GO:0033270,GO:0031641,GO:0043220,GO:0016020,GO:0016021,GO:0005886,GO:0032290,GO:0031643"	integral component of plasma membrane|structural constituent of myelin sheath|paranode region of axon|regulation of myelination|Schmidt-Lanterman incisure|membrane|integral component of membrane|plasma membrane|peripheral nervous system myelin formation|positive regulation of myelination	--	--
ENSMUSG00000046337	Fam178b	0	3.492490607	0.691	0.003	0	12	230.333	protein_coding	"family with sequence similarity 178, member B [Source:MGI Symbol;Acc:MGI:3026913]"	--	--	--	--
ENSMUSG00000031775	Pllp	0	2.786549912	0.604	0.004	0	12	151	protein_coding	plasma membrane proteolipid [Source:MGI Symbol;Acc:MGI:1915051]	"GO:0016020,GO:0016021,GO:0006811,GO:0045121,GO:0019911,GO:0042552,GO:0043218,GO:0009611"	membrane|integral component of membrane|ion transport|membrane raft|structural constituent of myelin sheath|myelination|compact myelin|response to wounding	--	--
ENSMUSG00000066058	Cldn19	0	2.651278668	0.574	0.002	0	12	287	protein_coding	claudin 19 [Source:MGI Symbol;Acc:MGI:3033992]	"GO:0016021,GO:0005198,GO:0005923,GO:0016020,GO:0005886,GO:0005634,GO:0005737,GO:0030054,GO:0016323,GO:0005515,GO:0043297,GO:0043296,GO:0042802,GO:0019227,GO:0016338,GO:0120193"	integral component of membrane|structural molecule activity|bicellular tight junction|membrane|plasma membrane|nucleus|cytoplasm|cell junction|basolateral plasma membrane|protein binding|apical junction assembly|apical junction complex|identical protein binding|neuronal action potential propagation|calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules|tight junction organization	"mmu04514,mmu04530,mmu04670,mmu05160"	Cell adhesion molecules (CAMs)|Tight junction|Leukocyte transendothelial migration|Hepatitis C
ENSMUSG00000032854	Ugt8a	0	2.266179217	0.472	0.002	0	12	236	protein_coding	UDP galactosyltransferase 8A [Source:MGI Symbol;Acc:MGI:109522]	"GO:0016758,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0043231,GO:0006629,GO:0006665,GO:0008194,GO:0042552,GO:0002175,GO:0007010,GO:0030913,GO:0048812,GO:0008120,GO:0009247,GO:0006682,GO:0008489,GO:0047263"	"transferase activity, transferring hexosyl groups|membrane|integral component of membrane|transferase activity|transferase activity, transferring glycosyl groups|intracellular membrane-bounded organelle|lipid metabolic process|sphingolipid metabolic process|UDP-glycosyltransferase activity|myelination|protein localization to paranode region of axon|cytoskeleton organization|paranodal junction assembly|neuron projection morphogenesis|ceramide glucosyltransferase activity|glycolipid biosynthetic process|galactosylceramide biosynthetic process|UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity|N-acylsphingosine galactosyltransferase activity"	"mmu00565,mmu00600"	Ether lipid metabolism|Sphingolipid metabolism
ENSMUSG00000042662	Dusp15	0	1.902293765	0.4	0.001	0	12	400	protein_coding	dual specificity phosphatase-like 15 [Source:MGI Symbol;Acc:MGI:1934928]	"GO:0016791,GO:0004725,GO:0006470,GO:0008138,GO:0016311,GO:0016020,GO:0005886,GO:0016787,GO:0005829,GO:0004721,GO:0035335,GO:0000122,GO:0007179,GO:0070374,GO:0042127,GO:0046330,GO:0048713"	phosphatase activity|protein tyrosine phosphatase activity|protein dephosphorylation|protein tyrosine/serine/threonine phosphatase activity|dephosphorylation|membrane|plasma membrane|hydrolase activity|cytosol|phosphoprotein phosphatase activity|peptidyl-tyrosine dephosphorylation|negative regulation of transcription by RNA polymerase II|transforming growth factor beta receptor signaling pathway|positive regulation of ERK1 and ERK2 cascade|regulation of cell population proliferation|positive regulation of JNK cascade|regulation of oligodendrocyte differentiation	--	--
ENSMUSG00000046167	Gldn	0	1.839640635	0.374	0.001	0	12	374	protein_coding	gliomedin [Source:MGI Symbol;Acc:MGI:2388361]	"GO:0045162,GO:0016020,GO:0016021,GO:0005615,GO:0005886,GO:0009986,GO:0007275,GO:0042995,GO:0005576,GO:0005515,GO:0030424,GO:0030154,GO:0005581,GO:0007399,GO:0032528,GO:0086080,GO:0034113"	clustering of voltage-gated sodium channels|membrane|integral component of membrane|extracellular space|plasma membrane|cell surface|multicellular organism development|cell projection|extracellular region|protein binding|axon|cell differentiation|collagen trimer|nervous system development|microvillus organization|protein binding involved in heterotypic cell-cell adhesion|heterotypic cell-cell adhesion	--	--
ENSMUSG00000020264	Slc36a2	0	1.685594847	0.389	0.001	0	12	389	protein_coding	"solute carrier family 36 (proton/amino acid symporter), member 2 [Source:MGI Symbol;Acc:MGI:1891430]"	"GO:0016020,GO:0016021,GO:0005886,GO:0005737,GO:1902600,GO:0010155,GO:0015171,GO:0003333,GO:0015816,GO:0015187,GO:0015808,GO:0015824,GO:0015180,GO:0015193,GO:0035524,GO:0005280,GO:0015078,GO:0032973,GO:0070881,GO:1900925,GO:0015828"	membrane|integral component of membrane|plasma membrane|cytoplasm|proton transmembrane transport|regulation of proton transport|amino acid transmembrane transporter activity|amino acid transmembrane transport|glycine transport|glycine transmembrane transporter activity|L-alanine transport|proline transport|L-alanine transmembrane transporter activity|L-proline transmembrane transporter activity|proline transmembrane transport|amino acid:proton symporter activity|proton transmembrane transporter activity|amino acid export across plasma membrane|regulation of proline transport|positive regulation of glycine import across plasma membrane|tyrosine transport	--	--
ENSMUSG00000032355	Mlip	0	1.557056608	0.321	0.002	0	12	160.5	protein_coding	muscular LMNA-interacting protein [Source:MGI Symbol;Acc:MGI:1916892]	"GO:0016020,GO:0005886,GO:0005634,GO:0000122,GO:0005635,GO:0003714,GO:0016605,GO:0005521,GO:0042383,GO:0010614,GO:1903243,GO:0031981"	membrane|plasma membrane|nucleus|negative regulation of transcription by RNA polymerase II|nuclear envelope|transcription corepressor activity|PML body|lamin binding|sarcolemma|negative regulation of cardiac muscle hypertrophy|negative regulation of cardiac muscle hypertrophy in response to stress|nuclear lumen	--	--
ENSMUSG00000033579	Fa2h	0	1.331540363	0.294	0.002	0	12	147	protein_coding	fatty acid 2-hydroxylase [Source:MGI Symbol;Acc:MGI:2443327]	"GO:0016021,GO:0055114,GO:0016491,GO:0020037,GO:0005506,GO:0006629,GO:0008610,GO:0080132,GO:0016020,GO:0046872,GO:0005783,GO:0005789,GO:0006631,GO:0006633,GO:0043231,GO:0061436,GO:0031090,GO:0042127,GO:0042634,GO:0046513,GO:0006682,GO:0006679,GO:0032287,GO:0032286,GO:0001949,GO:0030258,GO:0044857"	integral component of membrane|oxidation-reduction process|oxidoreductase activity|heme binding|iron ion binding|lipid metabolic process|lipid biosynthetic process|fatty acid alpha-hydroxylase activity|membrane|metal ion binding|endoplasmic reticulum|endoplasmic reticulum membrane|fatty acid metabolic process|fatty acid biosynthetic process|intracellular membrane-bounded organelle|establishment of skin barrier|organelle membrane|regulation of cell population proliferation|regulation of hair cycle|ceramide biosynthetic process|galactosylceramide biosynthetic process|glucosylceramide biosynthetic process|peripheral nervous system myelin maintenance|central nervous system myelin maintenance|sebaceous gland cell differentiation|lipid modification|plasma membrane raft organization	--	--
ENSMUSG00000038421	Fcrla	0	2.286004682	0.6	0.002	0	13	300	protein_coding	Fc receptor-like A [Source:MGI Symbol;Acc:MGI:2138647]	"GO:0005737,GO:0030154,GO:0005515"	cytoplasm|cell differentiation|protein binding	--	--
ENSMUSG00000008193	Spib	0	2.005754494	0.539	0.001	0	13	539	protein_coding	Spi-B transcription factor (Spi-1/PU.1 related) [Source:MGI Symbol;Acc:MGI:892986]	"GO:0006355,GO:0003700,GO:0043565,GO:0003677,GO:0005634,GO:0045944,GO:0001228,GO:0000981,GO:0030154,GO:0006357,GO:0000980,GO:0005667,GO:0030225"	"regulation of transcription, DNA-templated|DNA-binding transcription factor activity|sequence-specific DNA binding|DNA binding|nucleus|positive regulation of transcription by RNA polymerase II|DNA-binding transcription activator activity, RNA polymerase II-specific|DNA-binding transcription factor activity, RNA polymerase II-specific|cell differentiation|regulation of transcription by RNA polymerase II|RNA polymerase II distal enhancer sequence-specific DNA binding|transcription factor complex|macrophage differentiation"	--	--
ENSMUSG00000105646	Gm30211	0	1.80021576	0.322	0	0	13	Inf	lncRNA	"predicted gene, 30211 [Source:MGI Symbol;Acc:MGI:5589370]"	--	--	--	--
ENSMUSG00000014030	Pax5	0	1.70006158	0.489	0	0	13	Inf	protein_coding	paired box 5 [Source:MGI Symbol;Acc:MGI:97489]	"GO:0003677,GO:0006355,GO:0005634,GO:0005654,GO:0005829,GO:0007275,GO:0045944,GO:0043231,GO:0005515,GO:0035914,GO:0007283,GO:0030154,GO:0000122,GO:0030534,GO:0001650,GO:0003700,GO:0007399,GO:0045893,GO:0045892,GO:0000978,GO:0001228,GO:0005667,GO:0021987,GO:0009887,GO:0048701,GO:0007568,GO:0071542,GO:0051573,GO:0021670"	"DNA binding|regulation of transcription, DNA-templated|nucleus|nucleoplasm|cytosol|multicellular organism development|positive regulation of transcription by RNA polymerase II|intracellular membrane-bounded organelle|protein binding|skeletal muscle cell differentiation|spermatogenesis|cell differentiation|negative regulation of transcription by RNA polymerase II|adult behavior|fibrillar center|DNA-binding transcription factor activity|nervous system development|positive regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|RNA polymerase II proximal promoter sequence-specific DNA binding|DNA-binding transcription activator activity, RNA polymerase II-specific|transcription factor complex|cerebral cortex development|animal organ morphogenesis|embryonic cranial skeleton morphogenesis|aging|dopaminergic neuron differentiation|negative regulation of histone H3-K9 methylation|lateral ventricle development"	mmu05202	Transcriptional misregulation in cancers
ENSMUSG00000042474	Fcmr	0	1.694491704	0.389	0	0	13	Inf	protein_coding	Fc fragment of IgM receptor [Source:MGI Symbol;Acc:MGI:1916419]	"GO:0016020,GO:0016021"	membrane|integral component of membrane	--	--
ENSMUSG00000104213	Ighd	0	1.453505193	0.339	0.001	0	13	339	IG_C_gene	immunoglobulin heavy constant delta [Source:MGI Symbol;Acc:MGI:96447]	"GO:0016020,GO:0016021,GO:0003823,GO:0034987,GO:0006910,GO:0006911,GO:0006958,GO:0042742,GO:0045087,GO:0050853,GO:0050871,GO:0009897,GO:0042571,GO:0016064,GO:0016446,GO:0030890,GO:0050776,GO:0019815"	"membrane|integral component of membrane|antigen binding|immunoglobulin receptor binding|phagocytosis, recognition|phagocytosis, engulfment|complement activation, classical pathway|defense response to bacterium|innate immune response|B cell receptor signaling pathway|positive regulation of B cell activation|external side of plasma membrane|immunoglobulin complex, circulating|immunoglobulin mediated immune response|somatic hypermutation of immunoglobulin genes|positive regulation of B cell proliferation|regulation of immune response|B cell receptor complex"	--	--
ENSMUSG00000030724	Cd19	0	1.398951204	0.45	0.001	0	13	450	protein_coding	CD19 antigen [Source:MGI Symbol;Acc:MGI:88319]	"GO:0016020,GO:0016021,GO:0002322,GO:0050864,GO:0050853,GO:0009897,GO:0005886,GO:0016064,GO:0032991,GO:0005887,GO:0002376,GO:0002250,GO:0005515,GO:0045121,GO:0043552,GO:0051281,GO:0019724,GO:0050855,GO:0050851,GO:0001923"	membrane|integral component of membrane|B cell proliferation involved in immune response|regulation of B cell activation|B cell receptor signaling pathway|external side of plasma membrane|plasma membrane|immunoglobulin mediated immune response|protein-containing complex|integral component of plasma membrane|immune system process|adaptive immune response|protein binding|membrane raft|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of release of sequestered calcium ion into cytosol|B cell mediated immunity|regulation of B cell receptor signaling pathway|antigen receptor-mediated signaling pathway|B-1 B cell differentiation	"mmu04151,mmu04640,mmu04662,mmu05340,mmu05169"	PI3K-Akt signaling pathway|Hematopoietic cell lineage|B cell receptor signaling pathway|Primary immunodeficiency|Epstein-Barr virus infection
ENSMUSG00000043243	Fam129c	0	1.377751481	0.383	0.001	0	13	383	protein_coding	"family with sequence similarity 129, member C [Source:MGI Symbol;Acc:MGI:3686743]"	"GO:0003674,GO:0008150,GO:0005575"	molecular_function|biological_process|cellular_component	--	--
ENSMUSG00000061311	Rag1	0	1.205565235	0.256	0	0	13	Inf	protein_coding	recombination activating 1 [Source:MGI Symbol;Acc:MGI:97848]	"GO:0046872,GO:0043565,GO:0004519,GO:0061630,GO:0033151,GO:0016740,GO:0016787,GO:0003677,GO:0005634,GO:0003824,GO:0008152,GO:0005515,GO:0090305,GO:0002250,GO:0004518,GO:0006325,GO:0008270,GO:0004842,GO:0010390,GO:0006310,GO:0008542,GO:0030183,GO:0043029,GO:0042802,GO:0042803,GO:0051865,GO:0005654,GO:0042393,GO:0043154,GO:0045580,GO:0070233,GO:0048538,GO:0070244,GO:0033077,GO:2000822,GO:1990238,GO:0002331,GO:0045582,GO:0097519,GO:1905347"	metal ion binding|sequence-specific DNA binding|endonuclease activity|ubiquitin protein ligase activity|V(D)J recombination|transferase activity|hydrolase activity|DNA binding|nucleus|catalytic activity|metabolic process|protein binding|nucleic acid phosphodiester bond hydrolysis|adaptive immune response|nuclease activity|chromatin organization|zinc ion binding|ubiquitin-protein transferase activity|histone monoubiquitination|DNA recombination|visual learning|B cell differentiation|T cell homeostasis|identical protein binding|protein homodimerization activity|protein autoubiquitination|nucleoplasm|histone binding|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of T cell differentiation|negative regulation of T cell apoptotic process|thymus development|negative regulation of thymocyte apoptotic process|T cell differentiation in thymus|regulation of behavioral fear response|double-stranded DNA endodeoxyribonuclease activity|pre-B cell allelic exclusion|positive regulation of T cell differentiation|DNA recombinase complex|endodeoxyribonuclease complex	"mmu04068,mmu05340"	FoxO signaling pathway|Primary immunodeficiency
ENSMUSG00000037922	Bank1	0	1.101462501	0.283	0.001	0	13	283	protein_coding	B cell scaffold protein with ankyrin repeats 1 [Source:MGI Symbol;Acc:MGI:2442120]	"GO:0005575,GO:0009617,GO:0005102,GO:0050731,GO:1990782,GO:0005515,GO:0051898,GO:0043410,GO:0045947,GO:0042113,GO:0050869,GO:1900165"	cellular_component|response to bacterium|signaling receptor binding|positive regulation of peptidyl-tyrosine phosphorylation|protein tyrosine kinase binding|protein binding|negative regulation of protein kinase B signaling|positive regulation of MAPK cascade|negative regulation of translational initiation|B cell activation|negative regulation of B cell activation|negative regulation of interleukin-6 secretion	--	--
ENSMUSG00000036905	C1qb	0	5.053071429	0.645	0.011	0	14	58.636	protein_coding	"complement component 1, q subcomponent, beta polypeptide [Source:MGI Symbol;Acc:MGI:88224]"	"GO:0005515,GO:0006958,GO:0005615,GO:0042803,GO:0005576,GO:0002376,GO:0045087,GO:0005581,GO:0048839,GO:0005623,GO:0098883,GO:0005602,GO:0045202,GO:0098794"	"protein binding|complement activation, classical pathway|extracellular space|protein homodimerization activity|extracellular region|immune system process|innate immune response|collagen trimer|inner ear development|cell|synapse pruning|complement component C1 complex|synapse|postsynapse"	"mmu04610,mmu05322,mmu05020,mmu05133,mmu05150,mmu05142"	Complement and coagulation cascades|Systemic lupus erythematosus|Prion diseases|Pertussis|Staphylococcus aureus infection|Chagas disease (American trypanosomiasis)
ENSMUSG00000036887	C1qa	0	5.025497075	0.593	0.008	0	14	74.125	protein_coding	"complement component 1, q subcomponent, alpha polypeptide [Source:MGI Symbol;Acc:MGI:88223]"	"GO:0005515,GO:0006958,GO:0005615,GO:0001774,GO:0005576,GO:0002376,GO:0045087,GO:0005581,GO:0010039,GO:0005623,GO:1901216,GO:0016322,GO:0150062,GO:0150064,GO:0048143,GO:0098883,GO:0045202,GO:0098794,GO:0007568,GO:0050808"	"protein binding|complement activation, classical pathway|extracellular space|microglial cell activation|extracellular region|immune system process|innate immune response|collagen trimer|response to iron ion|cell|positive regulation of neuron death|neuron remodeling|complement-mediated synapse pruning|vertebrate eye-specific patterning|astrocyte activation|synapse pruning|synapse|postsynapse|aging|synapse organization"	"mmu04610,mmu05322,mmu05020,mmu05133,mmu05150,mmu05142"	Complement and coagulation cascades|Systemic lupus erythematosus|Prion diseases|Pertussis|Staphylococcus aureus infection|Chagas disease (American trypanosomiasis)
ENSMUSG00000036896	C1qc	0	4.021595978	0.541	0.006	0	14	90.167	protein_coding	"complement component 1, q subcomponent, C chain [Source:MGI Symbol;Acc:MGI:88225]"	"GO:0005515,GO:0005615,GO:0005576,GO:0002376,GO:0045087,GO:0005581,GO:0030853,GO:0045650,GO:0005623,GO:0006958,GO:0098883,GO:0045202,GO:0098794"	"protein binding|extracellular space|extracellular region|immune system process|innate immune response|collagen trimer|negative regulation of granulocyte differentiation|negative regulation of macrophage differentiation|cell|complement activation, classical pathway|synapse pruning|synapse|postsynapse"	"mmu04610,mmu05322,mmu05020,mmu05133,mmu05150,mmu05142"	Complement and coagulation cascades|Systemic lupus erythematosus|Prion diseases|Pertussis|Staphylococcus aureus infection|Chagas disease (American trypanosomiasis)
ENSMUSG00000024397	Aif1	0	3.625856921	0.773	0.005	0	14	154.6	protein_coding	allograft inflammatory factor 1 [Source:MGI Symbol;Acc:MGI:1343098]	"GO:0005509,GO:0016020,GO:0046872,GO:0005886,GO:0005634,GO:0048471,GO:0005829,GO:0005515,GO:0005737,GO:0005856,GO:0042995,GO:0030027,GO:0003779,GO:0001934,GO:0010629,GO:0005884,GO:0043204,GO:0051015,GO:0045429,GO:0043066,GO:0001726,GO:0008284,GO:0006954,GO:1900087,GO:0034599,GO:0030041,GO:0030335,GO:0032587,GO:0051017,GO:2000778,GO:0048661,GO:0090271,GO:0001891,GO:0071346,GO:0048662,GO:2000406,GO:0090197,GO:0042102,GO:0014739,GO:0050921,GO:0071672,GO:0071673,GO:0071677,GO:0090026,GO:0001774,GO:0006911,GO:0016601,GO:0030046,GO:0051764,GO:0097178,GO:0021549,GO:0031668,GO:0032870,GO:0034097,GO:0048678,GO:0051384,GO:0051602,GO:0071315,GO:0071447"	"calcium ion binding|membrane|metal ion binding|plasma membrane|nucleus|perinuclear region of cytoplasm|cytosol|protein binding|cytoplasm|cytoskeleton|cell projection|lamellipodium|actin binding|positive regulation of protein phosphorylation|negative regulation of gene expression|actin filament|perikaryon|actin filament binding|positive regulation of nitric oxide biosynthetic process|negative regulation of apoptotic process|ruffle|positive regulation of cell population proliferation|inflammatory response|positive regulation of G1/S transition of mitotic cell cycle|cellular response to oxidative stress|actin filament polymerization|positive regulation of cell migration|ruffle membrane|actin filament bundle assembly|positive regulation of interleukin-6 secretion|positive regulation of smooth muscle cell proliferation|positive regulation of fibroblast growth factor production|phagocytic cup|cellular response to interferon-gamma|negative regulation of smooth muscle cell proliferation|positive regulation of T cell migration|positive regulation of chemokine secretion|positive regulation of T cell proliferation|positive regulation of muscle hyperplasia|positive regulation of chemotaxis|negative regulation of smooth muscle cell chemotaxis|positive regulation of smooth muscle cell chemotaxis|positive regulation of mononuclear cell migration|positive regulation of monocyte chemotaxis|microglial cell activation|phagocytosis, engulfment|Rac protein signal transduction|parallel actin filament bundle assembly|actin crosslink formation|ruffle assembly|cerebellum development|cellular response to extracellular stimulus|cellular response to hormone stimulus|response to cytokine|response to axon injury|response to glucocorticoid|response to electrical stimulus|cellular response to morphine|cellular response to hydroperoxide"	--	--
ENSMUSG00000024672	Ms4a7	0	2.899325108	0.407	0.005	0	14	81.4	protein_coding	"membrane-spanning 4-domains, subfamily A, member 7 [Source:MGI Symbol;Acc:MGI:1918846]"	"GO:0016021,GO:0016020,GO:0003674,GO:0008150,GO:0005575"	integral component of membrane|membrane|molecular_function|biological_process|cellular_component	--	--
ENSMUSG00000079419	Ms4a6c	0	2.340365541	0.547	0.007	0	14	78.143	protein_coding	"membrane-spanning 4-domains, subfamily A, member 6C [Source:MGI Symbol;Acc:MGI:2385644]"	"GO:0016021,GO:0016020"	integral component of membrane|membrane	--	--
ENSMUSG00000023992	Trem2	0	2.13736623	0.337	0.004	0	14	84.25	protein_coding	triggering receptor expressed on myeloid cells 2 isoform 1 precursor	"GO:0001530,GO:0002588,GO:0004888,GO:0005543,GO:0005576,GO:0005886,GO:0006911,GO:0016021,GO:0030316,GO:0031663,GO:0032497,GO:0032499,GO:0042834,GO:0045087,GO:0050731,GO:0050850,GO:0070374,GO:0070392,GO:0070891,GO:0071223,GO:0071224,GO:0097028,GO:0097110,GO:1903078,GO:1903082,GO:2000350"	"lipopolysaccharide binding|positive regulation of antigen processing and presentation of peptide antigen via MHC class II|transmembrane signaling receptor activity|phospholipid binding|extracellular region|plasma membrane|phagocytosis, engulfment|integral component of membrane|osteoclast differentiation|lipopolysaccharide-mediated signaling pathway|detection of lipopolysaccharide|detection of peptidoglycan|peptidoglycan binding|innate immune response|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of calcium-mediated signaling|positive regulation of ERK1 and ERK2 cascade|detection of lipoteichoic acid|lipoteichoic acid binding|cellular response to lipoteichoic acid|cellular response to peptidoglycan|dendritic cell differentiation|scaffold protein binding|positive regulation of protein localization to plasma membrane|positive regulation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of CD40 signaling pathway"	mmu04380	Osteoclast differentiation
ENSMUSG00000024675	Ms4a4c	0	1.786053349	0.349	0.005	0	14	69.8	protein_coding	"membrane-spanning 4-domains, subfamily A, member 4C [Source:MGI Symbol;Acc:MGI:1927656]"	"GO:0016020,GO:0016021,GO:0003674,GO:0008150,GO:0005575"	membrane|integral component of membrane|molecular_function|biological_process|cellular_component	--	--
ENSMUSG00000052160	Pld4	0	1.402615605	0.448	0.005	0	14	89.6	protein_coding	unnamed protein product	"GO:0002244,GO:0004630,GO:0005634,GO:0005783,GO:0005789,GO:0006909,GO:0016021,GO:0016042,GO:0032588,GO:0045335,GO:0070290"	hematopoietic progenitor cell differentiation|phospholipase D activity|nucleus|endoplasmic reticulum|endoplasmic reticulum membrane|phagocytosis|integral component of membrane|lipid catabolic process|trans-Golgi network membrane|phagocytic vesicle|N-acylphosphatidylethanolamine-specific phospholipase D activity	"mmu00564,mmu00565"	Glycerophospholipid metabolism|Ether lipid metabolism
ENSMUSG00000015947	Fcgr1	0	1.244389201	0.297	0.004	0	14	74.25	protein_coding	"Fc receptor, IgG, high affinity I [Source:MGI Symbol;Acc:MGI:95498]"	"GO:0016020,GO:0016021,GO:0009897,GO:0005886,GO:0009617,GO:0002376,GO:0045087,GO:0050776,GO:0050766,GO:0042742,GO:0019864,GO:0038094,GO:0045121,GO:0006898,GO:0007166,GO:0061098,GO:0060100,GO:0001798,GO:0042590,GO:0001805,GO:0006911,GO:0006910,GO:0001788,GO:0019884,GO:0019770,GO:0031774"	"membrane|integral component of membrane|external side of plasma membrane|plasma membrane|response to bacterium|immune system process|innate immune response|regulation of immune response|positive regulation of phagocytosis|defense response to bacterium|IgG binding|Fc-gamma receptor signaling pathway|membrane raft|receptor-mediated endocytosis|cell surface receptor signaling pathway|positive regulation of protein tyrosine kinase activity|positive regulation of phagocytosis, engulfment|positive regulation of type IIa hypersensitivity|antigen processing and presentation of exogenous peptide antigen via MHC class I|positive regulation of type III hypersensitivity|phagocytosis, engulfment|phagocytosis, recognition|antibody-dependent cellular cytotoxicity|antigen processing and presentation of exogenous antigen|IgG receptor activity|leukotriene receptor binding"	"mmu04145,mmu04640,mmu04666,mmu04380,mmu05202,mmu05221,mmu05322,mmu05150,mmu05152,mmu05140"	Phagosome|Hematopoietic cell lineage|Fc gamma R-mediated phagocytosis|Osteoclast differentiation|Transcriptional misregulation in cancers|Acute myeloid leukemia|Systemic lupus erythematosus|Staphylococcus aureus infection|Tuberculosis|Leishmaniasis
ENSMUSG00000026051	Ecrg4	0	4.758873564	0.838	0.019	0	15	44.105	protein_coding	augurin precursor	"GO:0005615,GO:0005737,GO:0007417,GO:0008285,GO:0009611,GO:0016324,GO:0030133,GO:0031045,GO:0031145,GO:0070314,GO:0090398"	extracellular space|cytoplasm|central nervous system development|negative regulation of cell proliferation|response to wounding|apical plasma membrane|transport vesicle|dense core granule|anaphase-promoting complex-dependent catabolic process|G1 to G0 transition|cellular senescence	--	--
ENSMUSG00000039323	Igfbp2	0	4.10882304	0.757	0.015	0	15	50.467	protein_coding	insulin-like growth factor binding protein 2 [Source:MGI Symbol;Acc:MGI:96437]	"GO:0005576,GO:0005520,GO:0005615,GO:0031410,GO:0016324,GO:0031994,GO:0040008,GO:0019838,GO:0042104,GO:0031995,GO:0043567,GO:0007165,GO:0007565,GO:0007568,GO:0007584,GO:0009612,GO:0010226,GO:0032355,GO:0032526,GO:0032870,GO:0042493,GO:0043627,GO:0048545,GO:0051384"	extracellular region|insulin-like growth factor binding|extracellular space|cytoplasmic vesicle|apical plasma membrane|insulin-like growth factor I binding|regulation of growth|growth factor binding|positive regulation of activated T cell proliferation|insulin-like growth factor II binding|regulation of insulin-like growth factor receptor signaling pathway|signal transduction|female pregnancy|aging|response to nutrient|response to mechanical stimulus|response to lithium ion|response to estradiol|response to retinoic acid|cellular response to hormone stimulus|response to drug|response to estrogen|response to steroid hormone|response to glucocorticoid	--	--
ENSMUSG00000001827	Folr1	0	3.204890828	0.559	0.006	0	15	93.167	protein_coding	folate receptor 1 (adult) [Source:MGI Symbol;Acc:MGI:95568]	"GO:0005542,GO:0061714,GO:1904447,GO:0016020,GO:0005886,GO:0031362,GO:0005634,GO:0031410,GO:0005576,GO:0016324,GO:0005768,GO:0038023,GO:0016323,GO:0031225,GO:0046658,GO:0008144,GO:0005903,GO:0031526,GO:0030136,GO:0017015,GO:0001947,GO:0061626,GO:0046655,GO:0051870,GO:0006620,GO:0015884,GO:0071231,GO:0003147,GO:0003253,GO:0031103,GO:0048678,GO:0060828,GO:0061713"	folic acid binding|folic acid receptor activity|folate import across plasma membrane|membrane|plasma membrane|anchored component of external side of plasma membrane|nucleus|cytoplasmic vesicle|extracellular region|apical plasma membrane|endosome|signaling receptor activity|basolateral plasma membrane|anchored component of membrane|anchored component of plasma membrane|drug binding|brush border|brush border membrane|clathrin-coated vesicle|regulation of transforming growth factor beta receptor signaling pathway|heart looping|pharyngeal arch artery morphogenesis|folic acid metabolic process|methotrexate binding|posttranslational protein targeting to endoplasmic reticulum membrane|folic acid transport|cellular response to folic acid|neural crest cell migration involved in heart formation|cardiac neural crest cell migration involved in outflow tract morphogenesis|axon regeneration|response to axon injury|regulation of canonical Wnt signaling pathway|anterior neural tube closure	"mmu04144,mmu01523"	Endocytosis|Antifolate resistance
ENSMUSG00000079436	Kcnj13	0	2.395372255	0.331	0.005	0	15	66.2	protein_coding	"potassium inwardly-rectifying channel, subfamily J, member 13 [Source:MGI Symbol;Acc:MGI:3781032]"	"GO:0016021,GO:0016020,GO:0006813,GO:0005242,GO:0006811,GO:0005244,GO:0034765,GO:1990573,GO:0071805,GO:0034220"	integral component of membrane|membrane|potassium ion transport|inward rectifier potassium channel activity|ion transport|voltage-gated ion channel activity|regulation of ion transmembrane transport|potassium ion import across plasma membrane|potassium ion transmembrane transport|ion transmembrane transport	mmu04974	Protein digestion and absorption
ENSMUSG00000028773	Fabp3	0	2.246278269	0.324	0.006	0	15	54	protein_coding	"fatty acid binding protein 3, muscle and heart [Source:MGI Symbol;Acc:MGI:95476]"	"GO:0008289,GO:0005615,GO:0042632,GO:0005829,GO:0005737,GO:0008092,GO:0005504,GO:0005324,GO:0015909,GO:2001245,GO:0036041,GO:0050543,GO:0070538,GO:0006631,GO:0032365,GO:0032868,GO:0042493,GO:0046320,GO:0055091,GO:0070542,GO:0071073,GO:0140214,GO:0016528"	lipid binding|extracellular space|cholesterol homeostasis|cytosol|cytoplasm|cytoskeletal protein binding|fatty acid binding|long-chain fatty acid transporter activity|long-chain fatty acid transport|regulation of phosphatidylcholine biosynthetic process|long-chain fatty acid binding|icosatetraenoic acid binding|oleic acid binding|fatty acid metabolic process|intracellular lipid transport|response to insulin|response to drug|regulation of fatty acid oxidation|phospholipid homeostasis|response to fatty acid|positive regulation of phospholipid biosynthetic process|positive regulation of long-chain fatty acid import into cell|sarcoplasm	mmu03320	PPAR signaling pathway
ENSMUSG00000058488	Kl	0	2.229503668	0.294	0.004	0	15	73.5	protein_coding	klotho [Source:MGI Symbol;Acc:MGI:1101771]	"GO:0016021,GO:0005975,GO:0004553,GO:0005615,GO:0007568,GO:0008543,GO:0008286,GO:0016020,GO:0005886,GO:0016787,GO:0016798,GO:0008152,GO:0005515,GO:0005576,GO:0055074,GO:0016324,GO:0003085,GO:0017134,GO:0008422,GO:0006112,GO:0002526,GO:0030501,GO:0042421,GO:0090080,GO:0004566,GO:0005104"	"integral component of membrane|carbohydrate metabolic process|hydrolase activity, hydrolyzing O-glycosyl compounds|extracellular space|aging|fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|membrane|plasma membrane|hydrolase activity|hydrolase activity, acting on glycosyl bonds|metabolic process|protein binding|extracellular region|calcium ion homeostasis|apical plasma membrane|negative regulation of systemic arterial blood pressure|fibroblast growth factor binding|beta-glucosidase activity|energy reserve metabolic process|acute inflammatory response|positive regulation of bone mineralization|norepinephrine biosynthetic process|positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway|beta-glucuronidase activity|fibroblast growth factor receptor binding"	"mmu00040,mmu04961,mmu04211"	Pentose and glucuronate interconversions|Endocrine and other factor-regulated calcium reabsorption|Longevity regulating pathway - mammal
ENSMUSG00000115625	2900040C04Rik	0	2.068244296	0.294	0.002	0	15	147	lncRNA	RIKEN cDNA 2900040C04 gene [Source:MGI Symbol;Acc:MGI:1920143]	--	--	--	--
ENSMUSG00000039672	Kcne2	0	2.035054088	0.279	0.001	0	15	279	protein_coding	"potassium voltage-gated channel, Isk-related subfamily, gene 2 [Source:MGI Symbol;Acc:MGI:1891123]"	"GO:0016020,GO:0006811,GO:0005249,GO:0006813,GO:0016021,GO:0005242,GO:0005251,GO:0015459,GO:0042803,GO:0044325,GO:1902282,GO:0007568,GO:0035690,GO:0043586,GO:0060306,GO:0060307,GO:0071805,GO:0086002,GO:0086005,GO:0086009,GO:0086011,GO:0086091,GO:0097623,GO:0098915,GO:1901379,GO:1901387,GO:1901800,GO:1901979,GO:1902159,GO:1902259,GO:1902260,GO:1903817,GO:1990573,GO:0005783,GO:0005794,GO:0005886,GO:0008076,GO:0009986"	membrane|ion transport|voltage-gated potassium channel activity|potassium ion transport|integral component of membrane|inward rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel regulator activity|protein homodimerization activity|ion channel binding|voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|aging|cellular response to drug|tongue development|regulation of membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|potassium ion transmembrane transport|cardiac muscle cell action potential involved in contraction|ventricular cardiac muscle cell action potential|membrane repolarization|membrane repolarization during action potential|regulation of heart rate by cardiac conduction|potassium ion export across plasma membrane|membrane repolarization during ventricular cardiac muscle cell action potential|regulation of potassium ion transmembrane transport|positive regulation of voltage-gated calcium channel activity|positive regulation of proteasomal protein catabolic process|regulation of inward rectifier potassium channel activity|regulation of cyclic nucleotide-gated ion channel activity|regulation of delayed rectifier potassium channel activity|negative regulation of delayed rectifier potassium channel activity|negative regulation of voltage-gated potassium channel activity|potassium ion import across plasma membrane|endoplasmic reticulum|Golgi apparatus|plasma membrane|voltage-gated potassium channel complex|cell surface	mmu04971	Gastric acid secretion
ENSMUSG00000052387	Trpm3	3.97E-280	2.275790073	0.346	0.008	1.28E-275	15	43.25	protein_coding	"transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]"	"GO:0016021,GO:0016020,GO:0006811,GO:0055085,GO:0005216,GO:0006812,GO:0034220,GO:0051262,GO:0005227,GO:0016048,GO:0050951,GO:0098655,GO:0005261"	integral component of membrane|membrane|ion transport|transmembrane transport|ion channel activity|cation transport|ion transmembrane transport|protein tetramerization|calcium activated cation channel activity|detection of temperature stimulus|sensory perception of temperature stimulus|cation transmembrane transport|cation channel activity	--	--
ENSMUSG00000005268	Prlr	2.11E-279	2.102916079	0.287	0.005	6.80E-275	15	57.4	protein_coding	prolactin receptor [Source:MGI Symbol;Acc:MGI:97763]	"GO:0016020,GO:0016021,GO:0046872,GO:0009897,GO:0009986,GO:0005515,GO:0009617,GO:0004896,GO:0017046,GO:0019901,GO:0120162,GO:0019955,GO:0043235,GO:0007595,GO:0061180,GO:0004925,GO:0038161,GO:0030155,GO:0007171,GO:0060736,GO:0007259,GO:0060749,GO:0060644,GO:0030856"	membrane|integral component of membrane|metal ion binding|external side of plasma membrane|cell surface|protein binding|response to bacterium|cytokine receptor activity|peptide hormone binding|protein kinase binding|positive regulation of cold-induced thermogenesis|cytokine binding|receptor complex|lactation|mammary gland epithelium development|prolactin receptor activity|prolactin signaling pathway|regulation of cell adhesion|activation of transmembrane receptor protein tyrosine kinase activity|prostate gland growth|receptor signaling pathway via JAK-STAT|mammary gland alveolus development|mammary gland epithelial cell differentiation|regulation of epithelial cell differentiation	"mmu04630,mmu04151,mmu04080,mmu04060,mmu04917"	Jak-STAT signaling pathway|PI3K-Akt signaling pathway|Neuroactive ligand-receptor interaction|Cytokine-cytokine receptor interaction|Prolactin signaling pathway
ENSMUSG00000030669	Calca	0	4.86788783	0.692	0.005	0	16	138.4	protein_coding	"calcitonin/calcitonin-related polypeptide, alpha [Source:MGI Symbol;Acc:MGI:2151253]"	"GO:0005576,GO:0005179,GO:0005615,GO:0005634,GO:0005737,GO:0043005,GO:0009408,GO:0006954,GO:0030424,GO:0008016,GO:0007631,GO:0006874,GO:1990090,GO:0005102,GO:0043025,GO:0050965,GO:0051480,GO:0048240,GO:0043195,GO:0007189,GO:0045776,GO:0007218,GO:0048265,GO:0007190,GO:0042311,GO:0030279,GO:0045986,GO:0001976,GO:0001984,GO:0031716,GO:0007165,GO:0007568,GO:0071356"	extracellular region|hormone activity|extracellular space|nucleus|cytoplasm|neuron projection|response to heat|inflammatory response|axon|regulation of heart contraction|feeding behavior|cellular calcium ion homeostasis|cellular response to nerve growth factor stimulus|signaling receptor binding|neuronal cell body|detection of temperature stimulus involved in sensory perception of pain|regulation of cytosolic calcium ion concentration|sperm capacitation|terminal bouton|adenylate cyclase-activating G protein-coupled receptor signaling pathway|negative regulation of blood pressure|neuropeptide signaling pathway|response to pain|activation of adenylate cyclase activity|vasodilation|negative regulation of ossification|negative regulation of smooth muscle contraction|nervous system process involved in regulation of systemic arterial blood pressure|artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure|calcitonin receptor binding|signal transduction|aging|cellular response to tumor necrosis factor	--	--
ENSMUSG00000059412	Fxyd2	0	3.780348401	0.473	0.005	0	16	94.6	protein_coding	FXYD domain-containing ion transport regulator 2 [Source:MGI Symbol;Acc:MGI:1195260]	"GO:0016020,GO:0099106,GO:0043269,GO:0016021,GO:0006811,GO:0006813,GO:0006814,GO:2000649,GO:0017080,GO:0008285,GO:0015672,GO:0071475,GO:1903406,GO:1903407,GO:0005886,GO:0005890,GO:0016323,GO:0043231"	membrane|ion channel regulator activity|regulation of ion transport|integral component of membrane|ion transport|potassium ion transport|sodium ion transport|regulation of sodium ion transmembrane transporter activity|sodium channel regulator activity|negative regulation of cell population proliferation|monovalent inorganic cation transport|cellular hyperosmotic salinity response|regulation of sodium:potassium-exchanging ATPase activity|negative regulation of sodium:potassium-exchanging ATPase activity|plasma membrane|sodium:potassium-exchanging ATPase complex|basolateral plasma membrane|intracellular membrane-bounded organelle	"mmu04024,mmu04022,mmu04911,mmu04918,mmu04919,mmu04260,mmu04261,mmu04970,mmu04972,mmu04976,mmu04973,mmu04974,mmu04978,mmu04960,mmu04961,mmu04964"	cAMP signaling pathway|cGMP - PKG signaling pathway|Insulin secretion|Thyroid hormone synthesis|Thyroid hormone signaling pathway|Cardiac muscle contraction|Adrenergic signaling in cardiomyocytes|Salivary secretion|Pancreatic secretion|Bile secretion|Carbohydrate digestion and absorption|Protein digestion and absorption|Mineral absorption|Aldosterone-regulated sodium reabsorption|Endocrine and other factor-regulated calcium reabsorption|Proximal tubule bicarbonate reclamation
ENSMUSG00000027581	Stmn3	0	3.675029381	0.626	0.007	0	16	89.429	protein_coding	stathmin-like 3 [Source:MGI Symbol;Acc:MGI:1277137]	"GO:0005737,GO:0031110,GO:0015631,GO:0031122,GO:0031175,GO:0005794,GO:0048471,GO:0005829,GO:0005515,GO:0030426,GO:0042995,GO:0043005,GO:0030424,GO:0051493,GO:0008022,GO:0001835,GO:0007019,GO:0019904,GO:0035021,GO:0043087"	cytoplasm|regulation of microtubule polymerization or depolymerization|tubulin binding|cytoplasmic microtubule organization|neuron projection development|Golgi apparatus|perinuclear region of cytoplasm|cytosol|protein binding|growth cone|cell projection|neuron projection|axon|regulation of cytoskeleton organization|protein C-terminus binding|blastocyst hatching|microtubule depolymerization|protein domain specific binding|negative regulation of Rac protein signal transduction|regulation of GTPase activity	--	--
ENSMUSG00000062380	Tubb3	0	3.598828414	0.604	0.005	0	16	120.8	protein_coding	"tubulin, beta 3 class III [Source:MGI Symbol;Acc:MGI:107813]"	"GO:0005525,GO:0007017,GO:0005874,GO:0003924,GO:0005200,GO:0071944,GO:0015630,GO:0005515,GO:0005737,GO:0000166,GO:0005856,GO:0030426,GO:0042995,GO:0000226,GO:0030182,GO:0030424,GO:0000278,GO:0043025,GO:0007411,GO:0030027,GO:0042277,GO:0030175,GO:1990791,GO:0038007,GO:0030425,GO:1990890"	GTP binding|microtubule-based process|microtubule|GTPase activity|structural constituent of cytoskeleton|cell periphery|microtubule cytoskeleton|protein binding|cytoplasm|nucleotide binding|cytoskeleton|growth cone|cell projection|microtubule cytoskeleton organization|neuron differentiation|axon|mitotic cell cycle|neuronal cell body|axon guidance|lamellipodium|peptide binding|filopodium|dorsal root ganglion development|netrin-activated signaling pathway|dendrite|netrin receptor binding	"mmu04145,mmu04540"	Phagosome|Gap junction
ENSMUSG00000022055	Nefl	0	3.175449504	0.462	0.003	0	16	154	protein_coding	"neurofilament, light polypeptide [Source:MGI Symbol;Acc:MGI:97313]"	"GO:0005882,GO:0061564,GO:0005883,GO:0005737,GO:0005515,GO:0042802,GO:0046982,GO:0043005,GO:0030426,GO:0045109,GO:0030424,GO:0048812,GO:0019904,GO:0008022,GO:0050885,GO:0000226,GO:0043524,GO:0005200,GO:0098685,GO:0031594,GO:0098981,GO:0050772,GO:1904115,GO:0051258,GO:0030674,GO:0043209,GO:0043274,GO:0008089,GO:0008090,GO:0060052,GO:0014012,GO:0019896,GO:0031133,GO:0033693,GO:0040011,GO:0045105,GO:0045110,GO:1903935,GO:0099184,GO:0009636,GO:0010033,GO:0021510,GO:0021766,GO:0021987,GO:0043434,GO:0051412,GO:0060074,GO:0099185,GO:1903937,GO:0099160,GO:0099182"	"intermediate filament|axon development|neurofilament|cytoplasm|protein binding|identical protein binding|protein heterodimerization activity|neuron projection|growth cone|intermediate filament organization|axon|neuron projection morphogenesis|protein domain specific binding|protein C-terminus binding|neuromuscular process controlling balance|microtubule cytoskeleton organization|negative regulation of neuron apoptotic process|structural constituent of cytoskeleton|Schaffer collateral - CA1 synapse|neuromuscular junction|cholinergic synapse|positive regulation of axonogenesis|axon cytoplasm|protein polymerization|protein binding, bridging|myelin sheath|phospholipase binding|anterograde axonal transport|retrograde axonal transport|neurofilament cytoskeleton organization|peripheral nervous system axon regeneration|axonal transport of mitochondrion|regulation of axon diameter|neurofilament bundle assembly|locomotion|intermediate filament polymerization or depolymerization|intermediate filament bundle assembly|response to sodium arsenite|structural constituent of postsynaptic intermediate filament cytoskeleton|response to toxic substance|response to organic substance|spinal cord development|hippocampus development|cerebral cortex development|response to peptide hormone|response to corticosterone|synapse maturation|postsynaptic intermediate filament cytoskeleton organization|response to acrylamide|postsynaptic intermediate filament cytoskeleton|presynaptic intermediate filament cytoskeleton"	mmu05014	Amyotrophic lateral sclerosis (ALS)
ENSMUSG00000061762	Tac1	0	2.785062038	0.363	0.003	0	16	121	protein_coding	tachykinin 1 [Source:MGI Symbol;Acc:MGI:98474]	"GO:0007217,GO:0005615,GO:0005886,GO:0005576,GO:0019731,GO:0051930,GO:0006954,GO:0048018,GO:0050830,GO:0009725,GO:0007204,GO:0030424,GO:0045087,GO:0050829,GO:1990090,GO:0043025,GO:0031640,GO:0061844,GO:0007218,GO:0050671,GO:0019233,GO:0050965,GO:0051496,GO:0003085,GO:0010634,GO:1901216,GO:0010459,GO:0002675,GO:1901215,GO:0008217,GO:0008306,GO:0032230,GO:0048265,GO:0007616,GO:0032224,GO:0045760,GO:0019732,GO:0035815,GO:1904058,GO:0001878,GO:0045778,GO:0046878,GO:1902093,GO:2000854,GO:0031835,GO:0031836,GO:0031837,GO:0007268,GO:0032496,GO:0043278"	"tachykinin receptor signaling pathway|extracellular space|plasma membrane|extracellular region|antibacterial humoral response|regulation of sensory perception of pain|inflammatory response|receptor ligand activity|defense response to Gram-positive bacterium|response to hormone|positive regulation of cytosolic calcium ion concentration|axon|innate immune response|defense response to Gram-negative bacterium|cellular response to nerve growth factor stimulus|neuronal cell body|killing of cells of other organism|antimicrobial humoral immune response mediated by antimicrobial peptide|neuropeptide signaling pathway|positive regulation of lymphocyte proliferation|sensory perception of pain|detection of temperature stimulus involved in sensory perception of pain|positive regulation of stress fiber assembly|negative regulation of systemic arterial blood pressure|positive regulation of epithelial cell migration|positive regulation of neuron death|negative regulation of heart rate|positive regulation of acute inflammatory response|negative regulation of neuron death|regulation of blood pressure|associative learning|positive regulation of synaptic transmission, GABAergic|response to pain|long-term memory|positive regulation of synaptic transmission, cholinergic|positive regulation of action potential|antifungal humoral response|positive regulation of renal sodium excretion|positive regulation of sensory perception of pain|response to yeast|positive regulation of ossification|positive regulation of saliva secretion|positive regulation of flagellated sperm motility|positive regulation of corticosterone secretion|substance P receptor binding|neuromedin K receptor binding|substance K receptor binding|chemical synaptic transmission|response to lipopolysaccharide|response to morphine"	mmu04080	Neuroactive ligand-receptor interaction
ENSMUSG00000024256	Adcyap1	0	2.760292638	0.319	0	0	16	Inf	protein_coding	adenylate cyclase activating polypeptide 1 [Source:MGI Symbol;Acc:MGI:105094]	"GO:0007186,GO:0005576,GO:0005179,GO:0030073,GO:0016521,GO:0031858,GO:0005615,GO:0045944,GO:0001932,GO:0010628,GO:0032755,GO:0043547,GO:0031175,GO:0007204,GO:0043005,GO:0046034,GO:0045860,GO:0001662,GO:0060253,GO:0010976,GO:0005102,GO:0007399,GO:0001541,GO:0008284,GO:0007218,GO:0070374,GO:0120162,GO:0019233,GO:0008277,GO:0043267,GO:0032880,GO:0043195,GO:0007189,GO:0005184,GO:0034260,GO:0097755,GO:0090274,GO:0045786,GO:0019933,GO:0001821,GO:0002865,GO:0002878,GO:0007190,GO:0010656,GO:0043950,GO:0051968,GO:0060078,GO:0060124,GO:0070445,GO:0071651,GO:0051428,GO:0043204,GO:0021983,GO:0042594,GO:0045471,GO:0071385"	"G protein-coupled receptor signaling pathway|extracellular region|hormone activity|insulin secretion|pituitary adenylate cyclase activating polypeptide activity|pituitary adenylate cyclase-activating polypeptide receptor binding|extracellular space|positive regulation of transcription by RNA polymerase II|regulation of protein phosphorylation|positive regulation of gene expression|positive regulation of interleukin-6 production|positive regulation of GTPase activity|neuron projection development|positive regulation of cytosolic calcium ion concentration|neuron projection|ATP metabolic process|positive regulation of protein kinase activity|behavioral fear response|negative regulation of glial cell proliferation|positive regulation of neuron projection development|signaling receptor binding|nervous system development|ovarian follicle development|positive regulation of cell population proliferation|neuropeptide signaling pathway|positive regulation of ERK1 and ERK2 cascade|positive regulation of cold-induced thermogenesis|sensory perception of pain|regulation of G protein-coupled receptor signaling pathway|negative regulation of potassium ion transport|regulation of protein localization|terminal bouton|adenylate cyclase-activating G protein-coupled receptor signaling pathway|neuropeptide hormone activity|negative regulation of GTPase activity|positive regulation of blood vessel diameter|positive regulation of somatostatin secretion|negative regulation of cell cycle|cAMP-mediated signaling|histamine secretion|negative regulation of acute inflammatory response to antigenic stimulus|negative regulation of acute inflammatory response to non-antigenic stimulus|activation of adenylate cyclase activity|negative regulation of muscle cell apoptotic process|positive regulation of cAMP-mediated signaling|positive regulation of synaptic transmission, glutamatergic|regulation of postsynaptic membrane potential|positive regulation of growth hormone secretion|regulation of oligodendrocyte progenitor proliferation|positive regulation of chemokine (C-C motif) ligand 5 production|peptide hormone receptor binding|perikaryon|pituitary gland development|response to starvation|response to ethanol|cellular response to glucocorticoid stimulus"	"mmu04911,mmu04924"	Insulin secretion|Renin secretion
ENSMUSG00000048070	Pirt	0	2.062256906	0.264	0.001	0	16	264	protein_coding	phosphoinositide-interacting regulator of transient receptor potential channels [Source:MGI Symbol;Acc:MGI:2443635]	"GO:0016020,GO:0016021,GO:0005886,GO:0009408,GO:0044325,GO:0005547,GO:0048015,GO:2001259,GO:0048266,GO:1902936"	"membrane|integral component of membrane|plasma membrane|response to heat|ion channel binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-mediated signaling|positive regulation of cation channel activity|behavioral response to pain|phosphatidylinositol bisphosphate binding"	--	--
ENSMUSG00000046275	Trarg1	0	1.827677439	0.253	0.002	0	16	126.5	protein_coding	"tumor suppressor candidate 5, partial"	"GO:0005886,GO:0012505,GO:0016020,GO:0016021,GO:0030659,GO:0032869,GO:0044381,GO:0048471,GO:0072659,GO:0099500,GO:0099638"	plasma membrane|endomembrane system|membrane|integral component of membrane|cytoplasmic vesicle membrane|cellular response to insulin stimulus|glucose import in response to insulin stimulus|perinuclear region of cytoplasm|protein localization to plasma membrane|vesicle fusion to plasma membrane|endosome to plasma membrane protein transport	--	--
ENSMUSG00000036564	Ndrg4	4.20E-281	2.068928219	0.264	0.003	1.35E-276	16	88	protein_coding	N-myc downstream regulated gene 4 [Source:MGI Symbol;Acc:MGI:2384590]	"GO:0005737,GO:0005739,GO:0007165,GO:0005829,GO:0016323,GO:0005789,GO:0010976,GO:0070374,GO:0005515,GO:0007420,GO:0048662,GO:0010642,GO:0014912,GO:0008542,GO:0048278,GO:0060973,GO:2001135,GO:0031253"	cytoplasm|mitochondrion|signal transduction|cytosol|basolateral plasma membrane|endoplasmic reticulum membrane|positive regulation of neuron projection development|positive regulation of ERK1 and ERK2 cascade|protein binding|brain development|negative regulation of smooth muscle cell proliferation|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of smooth muscle cell migration|visual learning|vesicle docking|cell migration involved in heart development|regulation of endocytic recycling|cell projection membrane	--	--
ENSMUSG00000033227	Wnt6	0	1.995237036	0.544	0.002	0	17	272	protein_coding	"wingless-type MMTV integration site family, member 6 [Source:MGI Symbol;Acc:MGI:98960]"	"GO:0005576,GO:0007275,GO:0005102,GO:0016055,GO:0005615,GO:0031012,GO:0010628,GO:0045893,GO:0030182,GO:0007165,GO:0009986,GO:0009887,GO:0001658,GO:0042475,GO:0007267,GO:0005109,GO:0045165,GO:0005788,GO:0060684,GO:0009798,GO:0070172,GO:0072079,GO:0072080"	"extracellular region|multicellular organism development|signaling receptor binding|Wnt signaling pathway|extracellular space|extracellular matrix|positive regulation of gene expression|positive regulation of transcription, DNA-templated|neuron differentiation|signal transduction|cell surface|animal organ morphogenesis|branching involved in ureteric bud morphogenesis|odontogenesis of dentin-containing tooth|cell-cell signaling|frizzled binding|cell fate commitment|endoplasmic reticulum lumen|epithelial-mesenchymal cell signaling|axis specification|positive regulation of tooth mineralization|nephron tubule formation|nephron tubule development"	"mmu04310,mmu04390,mmu04150,mmu04550,mmu04916,mmu05200,mmu05205,mmu05225,mmu05226,mmu05217,mmu05224,mmu04934,mmu05166,mmu05165"	Wnt signaling pathway|Hippo signaling pathway|mTOR signaling pathway|Signaling pathways regulating pluripotency of stem cells|Melanogenesis|Pathways in cancer|Proteoglycans in cancer|Hepatocellular carcinoma|Gastric cancer|Basal cell carcinoma|Breast cancer|Cushing's syndrome|HTLV-I infection|Human papillomavirus infection
ENSMUSG00000038077	Kcna6	0	1.902201729	0.544	0.003	0	17	181.333	protein_coding	"potassium voltage-gated channel, shaker-related, subfamily, member 6 [Source:MGI Symbol;Acc:MGI:96663]"	"GO:0016020,GO:0016021,GO:0055085,GO:0051260,GO:0005886,GO:0006811,GO:0005216,GO:0005249,GO:0005267,GO:0006813,GO:0071805,GO:0008076,GO:0005244,GO:0034765,GO:0005887,GO:0030424,GO:0005251,GO:0043679,GO:0034705,GO:0005515"	membrane|integral component of membrane|transmembrane transport|protein homooligomerization|plasma membrane|ion transport|ion channel activity|voltage-gated potassium channel activity|potassium channel activity|potassium ion transport|potassium ion transmembrane transport|voltage-gated potassium channel complex|voltage-gated ion channel activity|regulation of ion transmembrane transport|integral component of plasma membrane|axon|delayed rectifier potassium channel activity|axon terminus|potassium channel complex|protein binding	--	--
ENSMUSG00000038602	Slc35f1	0	1.738133491	0.468	0.001	0	17	468	protein_coding	"solute carrier family 35, member F1 [Source:MGI Symbol;Acc:MGI:2139810]"	"GO:0016021,GO:0022857,GO:0055085,GO:0016020,GO:0003674,GO:0008150,GO:0005575"	integral component of membrane|transmembrane transporter activity|transmembrane transport|membrane|molecular_function|biological_process|cellular_component	--	--
ENSMUSG00000064115	Cadm2	0	1.72419717	0.38	0.002	0	17	190	protein_coding	cell adhesion molecule 2 [Source:MGI Symbol;Acc:MGI:2442722]	"GO:0016020,GO:0016021,GO:0005886,GO:0005737,GO:0030054,GO:0045202,GO:0042995,GO:0005515,GO:0030424,GO:0007155,GO:0032809"	membrane|integral component of membrane|plasma membrane|cytoplasm|cell junction|synapse|cell projection|protein binding|axon|cell adhesion|neuronal cell body membrane	--	--
ENSMUSG00000015843	Rxrg	0	1.38904692	0.392	0.002	0	17	196	protein_coding	retinoid X receptor gamma [Source:MGI Symbol;Acc:MGI:98216]	"GO:0003677,GO:0003707,GO:0008270,GO:0006355,GO:0005634,GO:0003700,GO:0043565,GO:0046872,GO:0005737,GO:0045944,GO:0000977,GO:0043401,GO:0030154,GO:0090575,GO:0006357,GO:0004879,GO:0048856,GO:0031641,GO:0048384,GO:0032526,GO:0044323,GO:1901522"	"DNA binding|steroid hormone receptor activity|zinc ion binding|regulation of transcription, DNA-templated|nucleus|DNA-binding transcription factor activity|sequence-specific DNA binding|metal ion binding|cytoplasm|positive regulation of transcription by RNA polymerase II|RNA polymerase II regulatory region sequence-specific DNA binding|steroid hormone mediated signaling pathway|cell differentiation|RNA polymerase II transcription factor complex|regulation of transcription by RNA polymerase II|nuclear receptor activity|anatomical structure development|regulation of myelination|retinoic acid receptor signaling pathway|response to retinoic acid|retinoic acid-responsive element binding|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus"	"mmu04659,mmu04920,mmu03320,mmu04919,mmu05200,mmu05202,mmu05226,mmu05216,mmu05222,mmu05223"	Th17 cell differentiation|Adipocytokine signaling pathway|PPAR signaling pathway|Thyroid hormone signaling pathway|Pathways in cancer|Transcriptional misregulation in cancers|Gastric cancer|Thyroid cancer|Small cell lung cancer|Non-small cell lung cancer
ENSMUSG00000073680	Tmem88b	0	1.177556112	0.266	0.001	0	17	266	protein_coding	transmembrane protein 88B [Source:MGI Symbol;Acc:MGI:2444329]	"GO:0016020,GO:0016021,GO:0008150,GO:0005886,GO:0030165"	membrane|integral component of membrane|biological_process|plasma membrane|PDZ domain binding	--	--
ENSMUSG00000020374	Rasgef1c	0	1.150621373	0.291	0.001	0	17	291	protein_coding	"RasGEF domain family, member 1C [Source:MGI Symbol;Acc:MGI:1921813]"	"GO:0005622,GO:0005085,GO:0007264"	intracellular|guanyl-nucleotide exchange factor activity|small GTPase mediated signal transduction	--	--
ENSMUSG00000097789	Gm2115	0	1.065973897	0.329	0.001	0	17	329	protein_coding	predicted gene 2115 [Source:MGI Symbol;Acc:MGI:3780284]	"GO:0031224,GO:0016020,GO:0016021"	intrinsic component of membrane|membrane|integral component of membrane	--	--
ENSMUSG00000063531	Sema3e	0	1.05036309	0.304	0.001	0	17	304	protein_coding	"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E [Source:MGI Symbol;Acc:MGI:1340034]"	"GO:0005515,GO:0005615,GO:0005887,GO:0007275,GO:0005576,GO:0030215,GO:0030154,GO:0007399,GO:0001525,GO:0008360,GO:0050919,GO:0016525,GO:0071526,GO:0002040,GO:0045499,GO:0001755,GO:0030335,GO:0048843,GO:2000249,GO:0001953,GO:0001569,GO:0050808"	protein binding|extracellular space|integral component of plasma membrane|multicellular organism development|extracellular region|semaphorin receptor binding|cell differentiation|nervous system development|angiogenesis|regulation of cell shape|negative chemotaxis|negative regulation of angiogenesis|semaphorin-plexin signaling pathway|sprouting angiogenesis|chemorepellent activity|neural crest cell migration|positive regulation of cell migration|negative regulation of axon extension involved in axon guidance|regulation of actin cytoskeleton reorganization|negative regulation of cell-matrix adhesion|branching involved in blood vessel morphogenesis|synapse organization	mmu04360	Axon guidance
ENSMUSG00000039533	Mmd2	0	0.940883491	0.291	0.001	0	17	291	protein_coding	monocyte to macrophage differentiation-associated 2 [Source:MGI Symbol;Acc:MGI:1922354]	"GO:0016021,GO:0019835,GO:0016020,GO:0000139,GO:0005794,GO:0048471,GO:0006468,GO:0046579,GO:0045860,GO:0032880,GO:0004672,GO:0045666"	integral component of membrane|cytolysis|membrane|Golgi membrane|Golgi apparatus|perinuclear region of cytoplasm|protein phosphorylation|positive regulation of Ras protein signal transduction|positive regulation of protein kinase activity|regulation of protein localization|protein kinase activity|positive regulation of neuron differentiation	--	--
ENSMUSG00000025270	Alas2	0	4.283893511	0.825	0.001	0	18	825	protein_coding	"aminolevulinic acid synthase 2, erythroid [Source:MGI Symbol;Acc:MGI:87990]"	"GO:0003824,GO:0030170,GO:0033014,GO:0009058,GO:0016740,GO:0005759,GO:0003870,GO:0006778,GO:0005739,GO:0005743,GO:0006782,GO:0016746,GO:0006783,GO:0001666,GO:0006879,GO:0016594,GO:0030218,GO:0050662,GO:0042541"	"catalytic activity|pyridoxal phosphate binding|tetrapyrrole biosynthetic process|biosynthetic process|transferase activity|mitochondrial matrix|5-aminolevulinate synthase activity|porphyrin-containing compound metabolic process|mitochondrion|mitochondrial inner membrane|protoporphyrinogen IX biosynthetic process|transferase activity, transferring acyl groups|heme biosynthetic process|response to hypoxia|cellular iron ion homeostasis|glycine binding|erythrocyte differentiation|coenzyme binding|hemoglobin biosynthetic process"	"mmu00260,mmu00860"	"Glycine, serine and threonine metabolism|Porphyrin and chlorophyll metabolism"
ENSMUSG00000025889	Snca	0	2.940240476	0.544	0.007	0	18	77.714	protein_coding	"synuclein, alpha [Source:MGI Symbol;Acc:MGI:1277151]"	"GO:0005737,GO:0014059,GO:0016020,GO:0046872,GO:0005615,GO:0005507,GO:0005886,GO:0005634,GO:0005794,GO:0032991,GO:0048471,GO:0005829,GO:0030054,GO:0045202,GO:0003779,GO:0042802,GO:0005576,GO:0043231,GO:0030426,GO:0050808,GO:0005739,GO:0001933,GO:0019894,GO:0032496,GO:0042493,GO:0016234,GO:0000149,GO:0008270,GO:0042393,GO:0008021,GO:0006915,GO:0030424,GO:0031648,GO:0071902,GO:0043679,GO:0019904,GO:0015629,GO:0043066,GO:0047485,GO:0042416,GO:0042417,GO:0098794,GO:0043025,GO:0005509,GO:0016079,GO:0005515,GO:0006644,GO:0099512,GO:0006919,GO:0019899,GO:0005938,GO:0008017,GO:0005743,GO:0005759,GO:0043524,GO:0055114,GO:0016491,GO:0034599,GO:0098793,GO:0045807,GO:0007268,GO:0008344,GO:0005543,GO:1905606,GO:0043195,GO:0060291,GO:0030659,GO:0070555,GO:0000287,GO:0045921,GO:0043154,GO:0042775,GO:0031115,GO:1901216,GO:0048168,GO:0005856,GO:0060079,GO:0050729,GO:0001774,GO:0005791,GO:0006638,GO:0070840,GO:0006631,GO:0032026,GO:0043014,GO:0043030,GO:0051259,GO:0051281,GO:0048169,GO:0005758,GO:0010040,GO:0005741,GO:1901215,GO:0048156,GO:0048489,GO:0048487,GO:0005640,GO:0035493,GO:0043274,GO:0051219,GO:0043027,GO:0007006,GO:0051262,GO:0034341,GO:0030544,GO:0008198,GO:0001956,GO:0050544,GO:0001921,GO:0001963,GO:0010517,GO:0010642,GO:0014048,GO:0016082,GO:0022898,GO:0031623,GO:0032410,GO:0032769,GO:0035067,GO:0040012,GO:0045920,GO:0045963,GO:0046928,GO:0048148,GO:0050806,GO:0050812,GO:0051585,GO:0051612,GO:0051621,GO:0051622,GO:0060732,GO:0061024,GO:0070495,GO:0071280,GO:1901214,GO:1903284,GO:1903285,GO:1904715,GO:0031092,GO:1903136,GO:0033138,GO:0048488,GO:2000377,GO:0005840,GO:0030672,GO:0007568,GO:0042220,GO:0044344,GO:1904307"	"cytoplasm|regulation of dopamine secretion|membrane|metal ion binding|extracellular space|copper ion binding|plasma membrane|nucleus|Golgi apparatus|protein-containing complex|perinuclear region of cytoplasm|cytosol|cell junction|synapse|actin binding|identical protein binding|extracellular region|intracellular membrane-bounded organelle|growth cone|synapse organization|mitochondrion|negative regulation of protein phosphorylation|kinesin binding|response to lipopolysaccharide|response to drug|inclusion body|SNARE binding|zinc ion binding|histone binding|synaptic vesicle|apoptotic process|axon|protein destabilization|positive regulation of protein serine/threonine kinase activity|axon terminus|protein domain specific binding|actin cytoskeleton|negative regulation of apoptotic process|protein N-terminus binding|dopamine biosynthetic process|dopamine metabolic process|postsynapse|neuronal cell body|calcium ion binding|synaptic vesicle exocytosis|protein binding|phospholipid metabolic process|supramolecular fiber|activation of cysteine-type endopeptidase activity involved in apoptotic process|enzyme binding|cell cortex|microtubule binding|mitochondrial inner membrane|mitochondrial matrix|negative regulation of neuron apoptotic process|oxidation-reduction process|oxidoreductase activity|cellular response to oxidative stress|presynapse|positive regulation of endocytosis|chemical synaptic transmission|adult locomotory behavior|phospholipid binding|regulation of presynapse assembly|terminal bouton|long-term synaptic potentiation|cytoplasmic vesicle membrane|response to interleukin-1|magnesium ion binding|positive regulation of exocytosis|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|mitochondrial ATP synthesis coupled electron transport|negative regulation of microtubule polymerization|positive regulation of neuron death|regulation of neuronal synaptic plasticity|cytoskeleton|excitatory postsynaptic potential|positive regulation of inflammatory response|microglial cell activation|rough endoplasmic reticulum|neutral lipid metabolic process|dynein complex binding|fatty acid metabolic process|response to magnesium ion|alpha-tubulin binding|regulation of macrophage activation|protein complex oligomerization|positive regulation of release of sequestered calcium ion into cytosol|regulation of long-term neuronal synaptic plasticity|mitochondrial intermembrane space|response to iron(II) ion|mitochondrial outer membrane|negative regulation of neuron death|tau protein binding|synaptic vesicle transport|beta-tubulin binding|nuclear outer membrane|SNARE complex assembly|phospholipase binding|phosphoprotein binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|mitochondrial membrane organization|protein tetramerization|response to interferon-gamma|Hsp70 protein binding|ferrous iron binding|positive regulation of neurotransmitter secretion|arachidonic acid binding|positive regulation of receptor recycling|synaptic transmission, dopaminergic|regulation of phospholipase activity|negative regulation of platelet-derived growth factor receptor signaling pathway|regulation of glutamate secretion|synaptic vesicle priming|regulation of transmembrane transporter activity|receptor internalization|negative regulation of transporter activity|negative regulation of monooxygenase activity|negative regulation of histone acetylation|regulation of locomotion|negative regulation of exocytosis|negative regulation of dopamine metabolic process|regulation of neurotransmitter secretion|behavioral response to cocaine|positive regulation of synaptic transmission|regulation of acyl-CoA biosynthetic process|negative regulation of dopamine uptake involved in synaptic transmission|negative regulation of serotonin uptake|regulation of norepinephrine uptake|negative regulation of norepinephrine uptake|positive regulation of inositol phosphate biosynthetic process|membrane organization|negative regulation of thrombin-activated receptor signaling pathway|cellular response to copper ion|regulation of neuron death|positive regulation of glutathione peroxidase activity|positive regulation of hydrogen peroxide catabolic process|negative regulation of chaperone-mediated autophagy|platelet alpha granule membrane|cuprous ion binding|positive regulation of peptidyl-serine phosphorylation|synaptic vesicle endocytosis|regulation of reactive oxygen species metabolic process|ribosome|synaptic vesicle membrane|aging|response to cocaine|cellular response to fibroblast growth factor stimulus|response to desipramine"	"mmu05010,mmu05012"	Alzheimer's disease|Parkinson's disease
ENSMUSG00000006574	Slc4a1	0	2.853017501	0.316	0.002	0	18	158	protein_coding	"solute carrier family 4 (anion exchanger), member 1 [Source:MGI Symbol;Acc:MGI:109393]"	"GO:0016021,GO:0016020,GO:0005452,GO:0006820,GO:0008509,GO:0005886,GO:0009986,GO:0005515,GO:0006811,GO:0003779,GO:0042803,GO:0005887,GO:0098656,GO:1902476,GO:0006821,GO:0015698,GO:0016323,GO:0051453,GO:0030018,GO:0072659,GO:0051259,GO:0008022,GO:0015301,GO:0015701,GO:0019899,GO:0030506,GO:0015106,GO:0009898,GO:0014704,GO:0030492,GO:0014823,GO:0035811,GO:0007596,GO:0048821,GO:0042542,GO:0042102,GO:0006096,GO:0010037,GO:0017121,GO:0045852,GO:0046685,GO:0015108,GO:0030863"	integral component of membrane|membrane|inorganic anion exchanger activity|anion transport|anion transmembrane transporter activity|plasma membrane|cell surface|protein binding|ion transport|actin binding|protein homodimerization activity|integral component of plasma membrane|anion transmembrane transport|chloride transmembrane transport|chloride transport|inorganic anion transport|basolateral plasma membrane|regulation of intracellular pH|Z disc|protein localization to plasma membrane|protein complex oligomerization|protein C-terminus binding|anion:anion antiporter activity|bicarbonate transport|enzyme binding|ankyrin binding|bicarbonate transmembrane transporter activity|cytoplasmic side of plasma membrane|intercalated disc|hemoglobin binding|response to activity|negative regulation of urine volume|blood coagulation|erythrocyte development|response to hydrogen peroxide|positive regulation of T cell proliferation|glycolytic process|response to carbon dioxide|plasma membrane phospholipid scrambling|pH elevation|response to arsenic-containing substance|chloride transmembrane transporter activity|cortical cytoskeleton	mmu04966	Collecting duct acid secretion
ENSMUSG00000091694	Apol11b	0	1.962566613	0.263	0	0	18	Inf	protein_coding	apolipoprotein L 11b [Source:MGI Symbol;Acc:MGI:3036248]	"GO:0005576,GO:0008289,GO:0006869,GO:0042157,GO:0008150,GO:0005575"	extracellular region|lipid binding|lipid transport|lipoprotein metabolic process|biological_process|cellular_component	--	--
ENSMUSG00000051839	Gypa	0	1.856369795	0.263	0.001	0	18	263	protein_coding	glycophorin A [Source:MGI Symbol;Acc:MGI:95880]	"GO:0016021,GO:0016020,GO:0009897,GO:0042803,GO:0005887,GO:0007016,GO:0047484"	integral component of membrane|membrane|external side of plasma membrane|protein homodimerization activity|integral component of plasma membrane|cytoskeletal anchoring at plasma membrane|regulation of response to osmotic stress	"mmu04640,mmu05144"	Hematopoietic cell lineage|Malaria
ENSMUSG00000073400	Trim10	0	1.77521582	0.298	0	0	18	Inf	protein_coding	tripartite motif-containing 10 [Source:MGI Symbol;Acc:MGI:1338757]	"GO:0008270,GO:0005515,GO:0046872,GO:0005737,GO:0045087,GO:0030218,GO:0046597"	zinc ion binding|protein binding|metal ion binding|cytoplasm|innate immune response|erythrocyte differentiation|negative regulation of viral entry into host cell	--	--
ENSMUSG00000073940	Hbb-bt	1.45E-193	8.578860934	0.965	0.059	4.69E-189	18	16.356	protein_coding	"hemoglobin, beta adult t chain [Source:MGI Symbol;Acc:MGI:5474850]"	"GO:0020037,GO:0019825,GO:0015671,GO:0005833,GO:0046872,GO:0005615,GO:0098869,GO:0005344,GO:0030492,GO:0004601,GO:0031720,GO:0031721,GO:0031722,GO:0043177,GO:0042744,GO:0031838"	heme binding|oxygen binding|oxygen transport|hemoglobin complex|metal ion binding|extracellular space|cellular oxidant detoxification|oxygen carrier activity|hemoglobin binding|peroxidase activity|haptoglobin binding|hemoglobin alpha binding|hemoglobin beta binding|organic acid binding|hydrogen peroxide catabolic process|haptoglobin-hemoglobin complex	"mmu05144,mmu05143"	Malaria|African trypanosomiasis
ENSMUSG00000038871	Bpgm	2.43E-193	3.228863538	0.614	0.021	7.85E-189	18	29.238	protein_coding	"2,3-bisphosphoglycerate mutase [Source:MGI Symbol;Acc:MGI:1098242]"	"GO:0006096,GO:0003824,GO:0016868,GO:0004619,GO:0016787,GO:0016853,GO:0004082,GO:0048821"	"glycolytic process|catalytic activity|intramolecular transferase activity, phosphotransferases|phosphoglycerate mutase activity|hydrolase activity|isomerase activity|bisphosphoglycerate mutase activity|erythrocyte development"	"mmu00010,mmu00260"	"Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism"
ENSMUSG00000024588	Fech	5.73E-122	2.041035822	0.456	0.018	1.85E-117	18	25.333	protein_coding	ferrochelatase [Source:MGI Symbol;Acc:MGI:95513]	"GO:0004325,GO:0006783,GO:0006779,GO:0016829"	ferrochelatase activity|heme biosynthetic process|porphyrin-containing compound biosynthetic process|lyase activity	mmu00860	Porphyrin and chlorophyll metabolism
ENSMUSG00000027562	Car2	1.04E-63	2.921465367	0.333	0.019	3.35E-59	18	17.526	protein_coding	carbonic anhydrase 2 [Source:MGI Symbol;Acc:MGI:88269]	"GO:0008270,GO:0004089,GO:0016020,GO:0046872,GO:0005615,GO:0005886,GO:0005829,GO:0005737,GO:0045177,GO:0006885,GO:0016323,GO:0016829,GO:0030424,GO:0005902,GO:0043209,GO:0045672,GO:0045780,GO:0002009,GO:0032230,GO:0044070,GO:0015670,GO:0032849,GO:0038166,GO:0046903,GO:2001225,GO:0004064,GO:0001822,GO:0009268,GO:0010033,GO:0010043,GO:0042475,GO:0043627,GO:0048545,GO:0051453,GO:0071498,GO:2001150"	"zinc ion binding|carbonate dehydratase activity|membrane|metal ion binding|extracellular space|plasma membrane|cytosol|cytoplasm|apical part of cell|regulation of pH|basolateral plasma membrane|lyase activity|axon|microvillus|myelin sheath|positive regulation of osteoclast differentiation|positive regulation of bone resorption|morphogenesis of an epithelium|positive regulation of synaptic transmission, GABAergic|regulation of anion transport|carbon dioxide transport|positive regulation of cellular pH reduction|angiotensin-activated signaling pathway|secretion|regulation of chloride transport|arylesterase activity|kidney development|response to pH|response to organic substance|response to zinc ion|odontogenesis of dentin-containing tooth|response to estrogen|response to steroid hormone|regulation of intracellular pH|cellular response to fluid shear stress|positive regulation of dipeptide transmembrane transport"	"mmu00910,mmu04971,mmu04972,mmu04976,mmu04964,mmu04966"	Nitrogen metabolism|Gastric acid secretion|Pancreatic secretion|Bile secretion|Proximal tubule bicarbonate reclamation|Collecting duct acid secretion