Reference list | upload_1 Mapped IDs: 14997 out of 15062 | 1056 out of 1075 Unmapped IDs: 6702 | 1324 Multiple mapping information: 944 | 35 Analysis Type: PANTHER Overrepresentation Test (Released 20181010) Annotation Version and Release Date: GO Ontology database Released 2018-09-06 Analyzed List: upload_1 (Homo sapiens) Reference List: measured_genes.txt (Homo sapiens) There are duplicate IDs in the file. The unique set of IDs will be used. Test Type: FISHER Correction: BONFERRONI Bonferroni count: 7833 GO biological process complete measured_genes.txt - REFLIST (15062) upload_1 (1075) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (P-value) type I interferon signaling pathway (GO:0060337) 50 20 3.57 + 5.60 1.28E-04 cellular response to type I interferon (GO:0071357) 50 20 3.57 + 5.60 1.28E-04 SRP-dependent cotranslational protein targeting to membrane (GO:0006614) 88 33 6.28 + 5.25 1.24E-08 response to type I interferon (GO:0034340) 55 20 3.93 + 5.09 4.63E-04 cotranslational protein targeting to membrane (GO:0006613) 92 33 6.57 + 5.03 3.32E-08 negative regulation of viral genome replication (GO:0045071) 48 17 3.43 + 4.96 6.11E-03 protein targeting to ER (GO:0045047) 100 33 7.14 + 4.62 2.08E-07 negative regulation of viral life cycle (GO:1903901) 63 20 4.50 + 4.45 2.83E-03 establishment of protein localization to endoplasmic reticulum (GO:0072599) 104 33 7.42 + 4.45 4.91E-07 acute inflammatory response (GO:0002526) 51 16 3.64 + 4.40 4.68E-02 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) 113 34 8.06 + 4.22 8.28E-07 negative regulation of viral process (GO:0048525) 77 22 5.50 + 4.00 3.40E-03 protein localization to endoplasmic reticulum (GO:0070972) 125 33 8.92 + 3.70 2.55E-05 defense response to virus (GO:0051607) 147 36 10.49 + 3.43 2.74E-05 protein targeting to membrane (GO:0006612) 140 34 9.99 + 3.40 8.89E-05 translational initiation (GO:0006413) 136 33 9.71 + 3.40 1.48E-04 defense response to other organism (GO:0098542) 291 67 20.77 + 3.23 6.15E-11 defense response to bacterium (GO:0042742) 138 30 9.85 + 3.05 4.96E-03 humoral immune response (GO:0006959) 130 27 9.28 + 2.91 3.74E-02 inflammatory response (GO:0006954) 349 69 24.91 + 2.77 1.51E-08 response to virus (GO:0009615) 223 44 15.92 + 2.76 2.28E-04 innate immune response (GO:0045087) 473 89 33.76 + 2.64 1.40E-10 nuclear-transcribed mRNA catabolic process (GO:0000956) 186 34 13.28 + 2.56 3.01E-02 defense response (GO:0006952) 886 159 63.24 + 2.51 6.30E-20 response to other organism (GO:0051707) 633 106 45.18 + 2.35 2.66E-10 response to external biotic stimulus (GO:0043207) 633 106 45.18 + 2.35 2.66E-10 response to bacterium (GO:0009617) 413 69 29.48 + 2.34 1.04E-05 response to biotic stimulus (GO:0009607) 661 108 47.18 + 2.29 5.47E-10 positive regulation of defense response (GO:0031349) 300 49 21.41 + 2.29 4.99E-03 regulation of multi-organism process (GO:0043900) 313 49 22.34 + 2.19 1.48E-02 regulation of innate immune response (GO:0045088) 302 47 21.55 + 2.18 2.83E-02 regulation of signaling receptor activity (GO:0010469) 305 47 21.77 + 2.16 4.95E-02 immune response (GO:0006955) 1209 185 86.29 + 2.14 7.77E-17 cytokine-mediated signaling pathway (GO:0019221) 479 72 34.19 + 2.11 3.29E-04 positive regulation of cytokine production (GO:0001819) 334 50 23.84 + 2.10 4.58E-02 positive regulation of immune response (GO:0050778) 517 77 36.90 + 2.09 1.44E-04 regulation of cytokine production (GO:0001817) 533 77 38.04 + 2.02 3.83E-04 regulation of defense response (GO:0031347) 557 80 39.75 + 2.01 2.80E-04 regulation of immune response (GO:0050776) 740 103 52.82 + 1.95 1.22E-05 positive regulation of immune system process (GO:0002684) 741 102 52.89 + 1.93 2.07E-05 regulation of response to external stimulus (GO:0032101) 598 81 42.68 + 1.90 1.92E-03 immune effector process (GO:0002252) 809 108 57.74 + 1.87 3.60E-05 response to external stimulus (GO:0009605) 1493 188 106.56 + 1.76 2.23E-09 cellular response to cytokine stimulus (GO:0071345) 750 94 53.53 + 1.76 6.23E-03 animal organ morphogenesis (GO:0009887) 680 85 48.53 + 1.75 2.65E-02 response to cytokine (GO:0034097) 819 102 58.45 + 1.74 2.14E-03 immune system process (GO:0002376) 1921 239 137.10 + 1.74 1.39E-12 regulation of immune system process (GO:0002682) 1134 139 80.94 + 1.72 2.79E-05 system process (GO:0003008) 1108 125 79.08 + 1.58 1.37E-02 cell surface receptor signaling pathway (GO:0007166) 1783 198 127.26 + 1.56 1.56E-05 multi-organism process (GO:0051704) 1778 185 126.90 + 1.46 4.65E-03 regulation of multicellular organismal process (GO:0051239) 2351 239 167.79 + 1.42 3.31E-04 animal organ development (GO:0048513) 2259 220 161.23 + 1.36 3.16E-02 response to chemical (GO:0042221) 3064 289 218.68 + 1.32 5.73E-03 signaling (GO:0023052) 3676 346 262.36 + 1.32 2.13E-04 cell communication (GO:0007154) 3765 347 268.71 + 1.29 1.98E-03 multicellular organismal process (GO:0032501) 4786 440 341.58 + 1.29 9.02E-06 signal transduction (GO:0007165) 3430 313 244.80 + 1.28 2.66E-02 response to stimulus (GO:0050896) 6023 527 429.87 + 1.23 6.34E-05 Unclassified (UNCLASSIFIED) 1730 141 123.47 + 1.14 0.00E00 metabolic process (GO:0008152) 8032 490 573.26 - .85 7.26E-03 organic substance metabolic process (GO:0071704) 7649 465 545.92 - .85 1.43E-02 primary metabolic process (GO:0044238) 7387 439 527.22 - .83 1.66E-03 macromolecule metabolic process (GO:0043170) 6268 363 447.36 - .81 2.99E-03 nitrogen compound metabolic process (GO:0006807) 7027 405 501.53 - .81 8.72E-05 cellular metabolic process (GO:0044237) 7448 429 531.58 - .81 1.16E-05 cellular macromolecule metabolic process (GO:0044260) 5443 298 388.48 - .77 1.26E-04 heterocycle metabolic process (GO:0046483) 4012 217 286.34 - .76 1.63E-02 cellular nitrogen compound metabolic process (GO:0034641) 4383 233 312.82 - .74 8.17E-04 cellular component organization (GO:0016043) 4563 240 325.67 - .74 1.33E-04 cellular component organization or biogenesis (GO:0071840) 4722 248 337.02 - .74 5.42E-05 nucleobase-containing compound metabolic process (GO:0006139) 3880 202 276.92 - .73 1.53E-03 nucleic acid metabolic process (GO:0090304) 3337 172 238.17 - .72 1.06E-02 organic cyclic compound biosynthetic process (GO:1901362) 2666 132 190.28 - .69 2.24E-02 cellular protein modification process (GO:0006464) 2598 128 185.42 - .69 2.65E-02 protein modification process (GO:0036211) 2598 128 185.42 - .69 2.65E-02 heterocycle biosynthetic process (GO:0018130) 2561 126 182.78 - .69 2.87E-02 macromolecule modification (GO:0043412) 2787 134 198.91 - .67 2.16E-03 cellular component assembly (GO:0022607) 2103 95 150.09 - .63 6.13E-03 cellular component biogenesis (GO:0044085) 2296 103 163.87 - .63 1.16E-03 organelle organization (GO:0006996) 2826 110 201.70 - .55 9.85E-10 protein modification by small protein conjugation or removal (GO:0070647) 826 27 58.95 - .46 4.34E-02 chromosome organization (GO:0051276) 860 26 61.38 - .42 5.48E-03 cell cycle (GO:0007049) 1157 34 82.58 - .41 1.35E-05 RNA processing (GO:0006396) 763 22 54.46 - .40 8.41E-03 cell cycle process (GO:0022402) 835 20 59.60 - .34 4.15E-05 mitotic cell cycle (GO:0000278) 609 13 43.47 - .30 1.31E-03 mitotic cell cycle process (GO:1903047) 531 10 37.90 - .26 1.91E-03 mitochondrion organization (GO:0007005) 396 7 28.26 - .25 4.82E-02