Category	Term	Count	%	PValue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
GOTERM_MF_DIRECT	GO:0005515~protein binding	269	82.76923076923077	1.347524207598506E-14	RB1, ISCA2, MSANTD3, ELK1, NDST1, ZC3H12C, MYB, EPHB2, SOX6, SEPHS1, TNS3, SOX4, SOX5, MEF2A, MEF2C, ARL15, PRKCE, RFX3, PRKCA, TMEM170A, WDR77, MAP1B, DDIT4, ULK2, TLN2, LETMD1, TP53, ASF1A, KCTD16, ANP32A, TXK, LPAR1, MTMR9, NLK, INPP5B, FXR1, SPAST, POM121C, ZBTB7A, N4BP1, CDK17, HEXIM1, STAT5B, EGR1, EGR2, FZD5, RCC2, SLC33A1, NR1D2, NR2F2, PA2G4, HNRNPF, CALU, ID4, STRN, CC2D1B, CPEB4, LIN54, HILPDA, SETD7, WASL, SPPL3, TMEM47, CSRP2, AIFM2, NCS1, TNFAIP8L1, TEAD1, TMED5, SREBF1, DUSP5, DUSP2, RRAS2, EMP1, F3, SIRT1, ZHX1, RHOB, PHF20L1, ZEB2, ZEB1, MDFIC, PSMA2, GAN, CSDE1, CNEP1R1, DCP2, CD44, HBEGF, SATB1, PTAFR, FIGN, METTL21A, SLC7A1, PURB, NEURL1B, PPP2CB, HAS2, MBNL3, PAK4, MAP3K3, MBD6, CSNK1A1, LSAMP, SNX24, GTF2H1, POU4F2, MIS18A, WT1, SMOC1, ETNK1, CCDC6, PLP2, SCARB1, CRTC1, FBXO28, SYAP1, ARID4B, MSMO1, MSI2, PRDM1, FGF2, MYLK3, IGF1R, FGF7, CCND2, LAMP1, TOM1, EP300, ARID2, IL6R, MAP3K4, CAST, SLC30A6, MMGT1, FBXW7, VPS33A, TMOD2, LMO2, DNAJB13, SDHD, FAM91A1, SRCIN1, PDIA6, FRMD3, STIM1, TOX, IL6ST, ARL8B, FBN2, PSMD12, CD151, KMT2A, SLC41A2, AK4, SLC1A5, FOXO3, ADIPOR2, FOXO1, HSP90B1, CAMSAP2, RAP1B, ATXN1, ATXN7, PSAP, NACC1, G3BP1, NLRP3, SRGAP2, ECT2, MYH10, TBC1D16, CD276, ZBTB18, ANKRD29, UBE2H, AKIRIN1, POU2F1, CBX5, BDNF, NEK6, FAM199X, QKI, TJAP1, UBE2W, CXCL12, CDK6, SP1, CNOT1, SP3, AAK1, TAB2, MDM4, FGFR2, ZNF652, PHF19, BCL2L1, CREBZF, KCNK5, GSK3B, DOCK4, KDM5C, MCFD2, THRA, CELF1, AMD1, HMGB2, PTEN, TNFAIP3, LMNB1, MFSD6, SPRED1, PPP2R5E, TRPS1, UQCRFS1, ERC1, TNPO1, CYTIP, KDM6A, KLF12, CHUK, APAF1, SECISBP2L, HUNK, ZFP91, RAD23B, MYH1, CREB1, ACOX1, IRF1, RASA1, CTDSP2, TOP1, MET, OTUB1, SMARCD1, ACSS3, RNF34, LRP5, CBL, MLLT6, CYTH2, MAPK8, VPS53, MKNK2, IGF2BP1, LRIG1, BNIP2, MAPK1, RPP14, E2F6, ATF7IP, SPAG7, KCNIP2, FOXJ3, HIP1R, SSRP1, ATP2B1, KLF3, ACVR2B, PNRC1, MTOR, PNRC2, TBX15, NFASC, PDCD4, SPRY2, PTPN4, TNRC6A	316	12754	19304	1.2884456204357828	7.818412584015277E-12	7.842590888223305E-12	7.559610804627619E-12
GOTERM_MF_DIRECT	GO:0003700~DNA-binding transcription factor activity	32	9.846153846153847	1.160200646029253E-9	CREBZF, THRA, PLAG1, PRDM1, FOXO3, ELK1, FOXO1, TRPS1, SOX6, ZBTB7A, TEAD1, SOX4, SOX5, MLXIP, MEF2A, SREBF1, EGR1, STAT5B, KLF12, EGR2, MEF2C, RFX3, NR2F2, KLF3, ZHX1, ZEB2, ZEB1, CREB1, NFIA, WT1, SP1, TP53	316	536	19304	3.647081050443983	6.752365229178992E-7	3.3761838799451266E-7	3.254362812112055E-7
GOTERM_MF_DIRECT	GO:0000978~RNA polymerase II cis-regulatory region sequence-specific DNA binding	50	15.384615384615385	1.997109185961523E-8	THRA, PRDM1, ELK1, MYB, SOX6, TEAD1, SOX4, SOX5, KDM6A, MEF2A, SREBF1, KLF12, MEF2C, EN2, RFX3, SIRT1, RAD23B, ZEB2, ZEB1, CREB1, IRF1, HOXB4, TOP1, TP53, ZBTB46, SATB1, PLAG1, FOXO3, FOXO1, NACC1, ZBTB7A, E2F6, ZNF267, MLXIP, EGR1, STAT5B, EGR2, POU2F1, FOXJ3, NR1D2, NR2F2, KLF3, POU4F2, TBX15, KLF7, NFIA, SP1, WT1, SP3, CC2D1B	316	1279	19304	2.388139468136697	1.1623108048031128E-5	3.8743918207653545E-6	3.7345941777480484E-6
GOTERM_MF_DIRECT	GO:0000981~DNA-binding transcription factor activity, RNA polymerase II-specific	49	15.076923076923077	3.272437693700149E-7	CREBZF, THRA, ELK1, MYB, SOX6, TEAD1, SOX4, SOX5, MEF2A, SREBF1, KLF12, MEF2C, EN2, ZFP91, RFX3, ZHX1, ZEB2, ZEB1, CREB1, IRF1, HOXB4, TP53, ZBTB46, SATB1, PLAG1, FOXO3, FOXO1, PURB, NACC1, ZBTB7A, E2F6, MLXIP, ZBTB18, EGR1, STAT5B, EGR2, POU2F1, FOXJ3, NR1D2, KLF3, POU4F2, TBX15, KLF7, NFIA, SP1, WT1, SP3, ZNF652, CC2D1B	316	1359	19304	2.20260616052384	1.9043776938820756E-4	4.761396844333717E-5	4.5895938654144585E-5
GOTERM_MF_DIRECT	GO:0140297~DNA-binding transcription factor binding	15	4.615384615384616	9.296780672201127E-7	RB1, MEF2A, MEF2C, CBX5, NEK6, LMO2, HMGB2, NLK, SIRT1, PURB, NFIA, MDFIC, EP300, NLRP3, ZBTB7A	316	172	19304	5.327494848395643	5.409265330829083E-4	1.0821452702442112E-4	1.0430987914209664E-4
GOTERM_MF_DIRECT	GO:0061629~RNA polymerase II-specific DNA-binding transcription factor binding	15	4.615384615384616	2.079645539010732E-6	RB1, MEF2A, GSK3B, EGR2, MEF2C, KDM5C, LMO2, ELK1, RAD23B, CREB1, SP1, SP3, ID4, EP300, TP53	316	184	19304	4.9800495321959275	0.0012096227781160929	2.01725617284041E-4	1.9444685789750345E-4
GOTERM_MF_DIRECT	GO:0000976~transcription cis-regulatory region binding	17	5.230769230769231	2.7662700472571986E-6	EGR1, EGR2, MEF2C, THRA, ZBTB46, HMGB2, RFX3, ARID4B, FOXO3, ELK1, WT1, SP1, IRF1, SOX6, TP53, SOX4, SOX5	316	244	19304	4.256173479975098	0.0016086760855928972	2.2999559535766994E-4	2.2169678521589834E-4
GOTERM_MF_DIRECT	GO:0001228~DNA-binding transcription activator activity, RNA polymerase II-specific	24	7.384615384615385	6.904385260699075E-6	MEF2A, MLXIP, SREBF1, EGR1, STAT5B, EGR2, MEF2C, POU2F1, PLAG1, FOXJ3, FOXO3, ELK1, FOXO1, POU4F2, KLF7, CREB1, NFIA, WT1, SP1, IRF1, MYB, TP53, SOX4, ZNF267	316	493	19304	2.973887590828562	0.004010303264325055	5.022940277158577E-4	4.841700164065226E-4
GOTERM_MF_DIRECT	GO:0001227~DNA-binding transcription repressor activity, RNA polymerase II-specific	20	6.153846153846154	8.288341469918814E-6	ZBTB18, KLF12, SATB1, ZBTB46, NR1D2, PRDM1, FOXO3, FOXO1, POU4F2, PURB, TBX15, ZEB2, ZEB1, TRPS1, NACC1, SP3, ZBTB7A, E2F6, TP53, CC2D1B	316	361	19304	3.3844103930712857	0.004812218720991135	5.3597941505475E-4	5.166399516249395E-4
GOTERM_MF_DIRECT	GO:0003677~DNA binding	39	12.0	3.185766247871442E-5	CREBZF, LIN54, KDM5C, KMT2A, SATB1, HMGB2, TNFAIP3, ARID4B, FOXO3, ATXN1, AIFM2, G3BP1, MAPK1, EP300, SOX6, ARID2, ZBTB7A, TEAD1, ZBTB18, MEF2A, SREBF1, EGR1, KLF12, EGR2, MEF2C, POU2F1, MBD6, RFX3, SSRP1, ZHX1, QKI, ZEB2, ZEB1, SP1, IRF1, TOP1, TP53, ZNF652, PHF19	316	1157	19304	2.059166548143934	0.018370619607228078	0.0018541159562611793	0.001787214865055879
GOTERM_MF_DIRECT	GO:0106310~protein serine kinase activity	19	5.846153846153846	3.524446797424074E-5	CDK17, GSK3B, MAP3K3, CSNK1A1, PRKCE, NEK6, HUNK, PRKCA, NLK, HIPK3, MTOR, MAPK8, CDK6, MKNK2, AAK1, ULK2, MAPK1, MAP3K4, PAK4	316	366	19304	3.1712665144912497	0.020303688769433892	0.0018647527600916464	0.001797467866686278
GOTERM_MF_DIRECT	GO:0004674~protein serine/threonine kinase activity	19	5.846153846153846	6.132566326047063E-5	GSK3B, MAP3K3, CHUK, CSNK1A1, PRKCE, NEK6, HUNK, PRKCA, NLK, ACVR2B, HIPK3, MTOR, MAPK8, MKNK2, AAK1, ULK2, MAPK1, TOP1, PAK4	316	382	19304	3.03843859765392	0.035063159906918884	0.0029742946681328257	0.002866974757427002
GOTERM_MF_DIRECT	GO:0043565~sequence-specific DNA binding	16	4.923076923076923	7.447448636980719E-5	ZBTB18, MEF2A, EGR1, EGR2, POU2F1, THRA, SATB1, PLAG1, FOXJ3, NR2F2, FOXO3, ELK1, FOXO1, WT1, SP1, NLRP3	316	285	19304	3.4295358649789027	0.042419765067637005	0.0033341654667098292	0.003213860527189372
GOTERM_MF_DIRECT	GO:0005524~ATP binding	46	14.153846153846153	9.949657141920978E-5	GSK3B, ACSS3, TXK, AK4, FIGN, NLK, MYLK3, HSP90B1, IGF1R, MAPK8, SPAST, G3BP1, MKNK2, MAPK1, NLRP3, EPHB2, SEPHS1, CNNM2, MYH10, MAP3K4, PAK4, CDK17, MAP3K3, UBE2H, CHUK, APAF1, CSNK1A1, PRKCE, NEK6, HUNK, PRKCA, NMNAT2, ATP2B1, ACVR2B, HIPK3, MTOR, MYH1, ITPKC, UBE2W, CDK6, ETNK1, AAK1, ULK2, TOP1, MET, FGFR2	316	1541	19304	1.8235405252219914	0.056265012217888044	0.004136214611855721	0.003986969754726906
GOTERM_MF_DIRECT	GO:1990837~sequence-specific double-stranded DNA binding	23	7.076923076923077	1.4161222790701146E-4	ZBTB18, SREBF1, EGR1, EGR2, KLF12, MEF2C, FOXJ3, EN2, RFX3, NR1D2, PRDM1, FOXO3, KLF3, ELK1, LMNB1, TBX15, CREB1, SP1, SP3, HOXB4, ZBTB7A, TEAD1, SOX4	316	560	19304	2.508996383363472	0.07911871862981457	0.005494554442792044	0.005296297323722228
GOTERM_MF_DIRECT	GO:0002039~p53 binding	8	2.4615384615384617	1.5676098819856034E-4	GSK3B, RNF34, SETD7, EP300, MDM4, SIRT1, TP53, POU4F2	316	71	19304	6.883223390978784	0.08720325547796393	0.005702180945722632	0.005496432148712022
GOTERM_MF_DIRECT	GO:0004672~protein kinase activity	14	4.3076923076923075	6.638846830754096E-4	CDK17, GSK3B, MAP3K3, CHUK, CSNK1A1, PRKCE, PRKCA, NLK, HIPK3, MTOR, AAK1, MET, MAP3K4, PAK4	316	277	19304	3.0875108531736966	0.32057552435300807	0.02272828738528755	0.021908194541488516
GOTERM_MF_DIRECT	GO:0003682~chromatin binding	20	6.153846153846154	0.0010275005353036638	MEF2A, SREBF1, SMARCD1, STAT5B, EGR2, MBD6, CBX5, KMT2A, SETD7, GTF2H1, ELK1, FOXO1, ZEB1, NFIA, SP3, EP300, TOP1, TP53, ASF1A, PHF19	316	523	19304	2.336084420456471	0.45026159850322056	0.033222517308151796	0.032023766683630855
GOTERM_MF_DIRECT	GO:0042802~identical protein binding	45	13.846153846153847	0.0022714974012054264	RB1, CREBZF, ISCA2, KDM5C, KMT2A, AMD1, FBXO28, PTEN, TNFAIP3, MSI2, FGF2, ADIPOR2, IGF1R, ATXN1, PSAP, TNFAIP8L1, MAPK1, HAS2, NLRP3, EPHB2, SEPHS1, SRGAP2, SLC16A2, KDM6A, HEXIM1, STAT5B, POU2F1, CBX5, APAF1, KCNIP2, FBXW7, LMO2, HIP1R, SIRT1, MTOR, CREB1, MIS18A, STIM1, SP1, CCDC6, IL6ST, MET, TP53, FGFR2, BCL2L1	316	1737	19304	1.5826064143765988	0.7338020936329249	0.06957955197376622	0.06706894958296022
GOTERM_MF_DIRECT	GO:0000977~RNA polymerase II transcription regulatory region sequence-specific DNA binding	15	4.615384615384616	0.002628527638561439	RB1, MEF2A, MLXIP, SREBF1, EGR1, MEF2C, SATB1, ZFP91, PURB, SP1, IRF1, TRPS1, SP3, E2F6, ZNF652	316	362	19304	2.5312958948178195	0.7838574598124499	0.07649015428213787	0.07373020026164837
GOTERM_MF_DIRECT	GO:0030165~PDZ domain binding	7	2.1538461538461537	0.0030052173984150992	DOCK4, ACOX1, CRIM1, PTEN, LPAR1, ATP2B1, ERC1	316	87	19304	4.915175323730541	0.8265160030847806	0.08328745361321847	0.08028223621480336
GOTERM_MF_DIRECT	GO:0002020~protease binding	8	2.4615384615384617	0.003247528355471069	GSK3B, STIM1, APAF1, CHL1, PSAP, TNFAIP3, TP53, F3	316	118	19304	4.141600514910963	0.8494013876414834	0.08392399112730928	0.0808958058804476
GOTERM_MF_DIRECT	GO:0001221~transcription coregulator binding	5	1.5384615384615385	0.003316583841800882	SREBF1, SP1, LMO2, EP300, FOXO3	316	38	19304	8.037974683544304	0.8553531192558496	0.08392399112730928	0.0808958058804476
GOTERM_MF_DIRECT	GO:1990841~promoter-specific chromatin binding	6	1.8461538461538463	0.005049360875826061	EGR1, PRDM1, SIRT1, TP53, POU4F2, FOXO1	316	68	19304	5.3901712583767685	0.9474595772853669	0.12244700123878198	0.11802881047243417
GOTERM_MF_DIRECT	GO:0031625~ubiquitin protein ligase binding	13	4.0	0.005277671511417269	RB1, GSK3B, EGR2, RNF34, FZD5, FBXW7, NEK6, PA2G4, NLK, FOXO1, UBE2W, TP53, OTUB1	316	311	19304	2.5535430827465504	0.9540287423864782	0.12286419278579402	0.11843094871620352
GOTERM_MF_DIRECT	GO:0043130~ubiquitin binding	7	2.1538461538461537	0.006547141521137728	FBXW7, TOM1, TNFAIP3, TAB2, RAD23B, N4BP1, OTUB1	316	102	19304	4.19235542318193	0.9781371146339825	0.14565316292474903	0.14039763642746428
GOTERM_MF_DIRECT	GO:0035035~histone acetyltransferase binding	4	1.2307692307692308	0.006757105496508976	MEF2A, EGR1, SP1, ZBTB7A	316	24	19304	10.181434599156118	0.9806677805377831	0.14565316292474903	0.14039763642746428
GOTERM_MF_DIRECT	GO:0005516~calmodulin binding	10	3.076923076923077	0.008997516531458017	CNN2, RGS4, MYH1, ITPKC, MKNK2, STRN, ATP2B1, ADD3, MYH10, CAMSAP2	316	215	19304	2.84133058581101	0.9948060193133238	0.18701980790387734	0.18027167050528384
GOTERM_MF_DIRECT	GO:0042803~protein homodimerization activity	22	6.769230769230769	0.011611256343664396	STAT5B, KMT2A, HMGCS1, CHUK, SLC33A1, HIP1R, NR2F2, SPPL3, FXR1, TBX15, SP1, ACOX1, STC2, PSAP, MUC13, SOX6, ECT2, SEPHS1, SRGAP2, IL6R, FGFR2, BCL2L1	316	750	19304	1.7919324894514768	0.9988832030404738	0.233025903172851	0.22461775202743883
GOTERM_MF_DIRECT	GO:0003680~minor groove of adenine-thymine-rich DNA binding	3	0.9230769230769231	0.013245667137732729	LIN54, MEF2C, KMT2A	316	11	19304	16.660529344073648	0.9995737518722884	0.25017456382278797	0.24114764657145027
GOTERM_MF_DIRECT	GO:0031490~chromatin DNA binding	6	1.8461538461538463	0.013325449275784239	THRA, EP300, TOX, FOXO3, FOXO1, KDM6A	316	86	19304	4.261995878716514	0.9995933457830151	0.25017456382278797	0.24114764657145027
GOTERM_MF_DIRECT	GO:0042826~histone deacetylase binding	7	2.1538461538461537	0.02131677913181538	MEF2A, MEF2C, MAPK8, CBX5, SP1, NACC1, TP53	316	132	19304	3.239547372458765	0.9999964212860991	0.3876989204598922	0.37370978415463835
GOTERM_MF_DIRECT	GO:0046872~metal ion binding	60	18.461538461538463	0.0238017545652259	LIN54, MCFD2, KDM5C, THRA, TNFAIP3, PRDM1, ZC3H12C, CSRP2, UQCRFS1, EP300, SEPHS1, ARID2, TNS3, MAP3K4, KDM6A, KLF12, PRKCE, LMO2, ZFP91, PRKCA, SDHD, ZHX1, SIRT1, PHF20L1, ZEB2, ZEB1, CTDSP2, TP53, RNF34, KMT2A, ZBTB46, PLAG1, SLC1A5, ADIPOR2, MLLT6, INPP5B, PPP2CB, NEURL1B, MKNK2, MBNL3, ZBTB7A, ZNF267, ZBTB18, EGR1, MAP3K3, EGR2, ATP2B1, KLF3, ACVR2B, MIS18A, SP1, WT1, SP3, TAB2, MDM4, ZNF652, PLEKHM3, FGFR2, PHF19, CPEB4	316	2812	19304	1.3034553540882656	0.9999991850532407	0.41977639869580224	0.40462982760884025
GOTERM_MF_DIRECT	GO:0015095~magnesium ion transmembrane transporter activity	3	0.9230769230769231	0.027393044708115884	MMGT1, SLC41A2, CNNM2	316	16	19304	11.454113924050635	0.9999999045996648	0.4689044711801013	0.4519852376839121
GOTERM_MF_DIRECT	GO:0004438~phosphatidylinositol-3-phosphate phosphatase activity	3	0.9230769230769231	0.030716163388858568	MTMR10, PTEN, MTMR9	316	17	19304	10.780342516753537	0.9999999869843778	0.5065144495677831	0.4882381549957497
GOTERM_MF_DIRECT	GO:0004915~interleukin-6 receptor activity	2	0.6153846153846154	0.03237028211784531	IL6ST, IL6R	316	2	19304	61.08860759493671	0.9999999951832599	0.5065144495677831	0.4882381549957497
GOTERM_MF_DIRECT	GO:0019981~interleukin-6 binding	2	0.6153846153846154	0.03237028211784531	IL6ST, IL6R	316	2	19304	61.08860759493671	0.9999999951832599	0.5065144495677831	0.4882381549957497
GOTERM_MF_DIRECT	GO:0003729~mRNA binding	10	3.076923076923077	0.03307139017796522	PURB, ZC3H12C, CELF1, NOVA2, G3BP1, IGF2BP1, MSI2, N4BP1, QKI, PTBP2	316	269	19304	2.2709519552021082	0.9999999968410198	0.5065144495677831	0.4882381549957497
GOTERM_MF_DIRECT	GO:0000900~mRNA regulatory element binding translation repressor activity	3	0.9230769230769231	0.03418967700972696	PURB, CELF1, CPEB4	316	18	19304	10.181434599156118	0.9999999983891592	0.5102151799913099	0.4918053539091493
GOTERM_MF_DIRECT	GO:0060090~molecular adaptor activity	8	2.4615384615384617	0.03584668913534245	RB1, SMARCD1, SP1, CNOT1, COL4A4, NLRP3, TAB2, LETMD1	316	189	19304	2.5857611680396486	0.9999999994070359	0.5215693269192326	0.5027498151231778
GOTERM_MF_DIRECT	GO:0004896~cytokine receptor activity	4	1.2307692307692308	0.036907166277346956	IL6ST, IL6R, F3, CD44	316	45	19304	5.430098452883263	0.9999999996874899	0.5239017261808763	0.5049980556485767
GOTERM_MF_DIRECT	GO:0001618~virus receptor activity	5	1.5384615384615385	0.041887909053659744	SCARB1, LAMP1, SLC1A5, SLC7A1, XPR1	316	80	19304	3.8180379746835444	0.9999999999847138	0.56251903515175	0.5422219565638002
GOTERM_MF_DIRECT	GO:0044877~protein-containing complex binding	11	3.3846153846153846	0.042374178859748146	RAP1B, SPAST, CBX5, CHUK, FZD5, KCNIP2, MAP1B, STRN, EPHB2, MTOR, IGF1R	316	327	19304	2.0549684512058217	0.9999999999886242	0.56251903515175	0.5422219565638002
GOTERM_MF_DIRECT	GO:0019899~enzyme binding	12	3.6923076923076925	0.04252721227951374	EGR1, MAPK8, CREB1, LAMP1, STC2, PRKCE, PTEN, MDM4, PRKCA, IL6R, SIRT1, TP53	316	372	19304	1.9706002449979585	0.9999999999896345	0.56251903515175	0.5422219565638002
GOTERM_MF_DIRECT	GO:0044729~hemi-methylated DNA-binding	2	0.6153846153846154	0.04816156598076984	EGR1, WT1	316	3	19304	40.72573839662447	0.9999999999996659	0.5839589875168343	0.5628883024002475
GOTERM_MF_DIRECT	GO:0004921~interleukin-11 receptor activity	2	0.6153846153846154	0.04816156598076984	IL6ST, IL6R	316	3	19304	40.72573839662447	0.9999999999996659	0.5839589875168343	0.5628883024002475
GOTERM_MF_DIRECT	GO:0005010~insulin-like growth factor receptor activity	2	0.6153846153846154	0.04816156598076984	CRIM1, IGF1R	316	3	19304	40.72573839662447	0.9999999999996659	0.5839589875168343	0.5628883024002475
GOTERM_MF_DIRECT	GO:0019970~interleukin-11 binding	2	0.6153846153846154	0.04816156598076984	IL6ST, IL6R	316	3	19304	40.72573839662447	0.9999999999996659	0.5839589875168343	0.5628883024002475
GOTERM_MF_DIRECT	GO:0017018~myosin phosphatase activity	5	1.5384615384615385	0.05405515921418179	DUSP5, PPP2CB, DUSP2, CTDSP2, PTEN	316	87	19304	3.5108395169503863	0.999999999999991	0.6420429114827306	0.6188764146766527
GOTERM_MF_DIRECT	GO:0004879~nuclear receptor activity	4	1.2307692307692308	0.05805049063953515	SREBF1, THRA, NR1D2, NR2F2	316	54	19304	4.525082044069386	0.9999999999999992	0.6740189402765455	0.6496986692356391
GOTERM_MF_DIRECT	GO:1901981~phosphatidylinositol phosphate binding	3	0.9230769230769231	0.0622496224101314	RNF34, NLRP3, SNX24	316	25	19304	7.330632911392405	0.9999999999999999	0.6740189402765455	0.6496986692356391
GOTERM_MF_DIRECT	GO:0051019~mitogen-activated protein kinase binding	3	0.9230769230769231	0.0622496224101314	DUSP2, PTAFR, SIRT1	316	25	19304	7.330632911392405	0.9999999999999999	0.6740189402765455	0.6496986692356391
GOTERM_MF_DIRECT	GO:0035033~histone deacetylase regulator activity	2	0.6153846153846154	0.06369594796427835	MAPK8, TP53	316	4	19304	30.544303797468356	1.0	0.6740189402765455	0.6496986692356391
GOTERM_MF_DIRECT	GO:0004897~ciliary neurotrophic factor receptor activity	2	0.6153846153846154	0.06369594796427835	IL6ST, IL6R	316	4	19304	30.544303797468356	1.0	0.6740189402765455	0.6496986692356391
GOTERM_MF_DIRECT	GO:0055105~ubiquitin-protein transferase inhibitor activity	2	0.6153846153846154	0.06369594796427835	SPRY2, OTUB1	316	4	19304	30.544303797468356	1.0	0.6740189402765455	0.6496986692356391
GOTERM_MF_DIRECT	GO:0019901~protein kinase binding	14	4.3076923076923075	0.0704343996764977	MEF2A, SREBF1, GSK3B, FZD5, RCC2, NEK6, FOXO3, SRCIN1, RHOB, RGS4, SPRED1, CCND2, SPRY2, BCL2L1	316	502	19304	1.7036663472691513	1.0	0.7320146537807439	0.7056017539020573
GOTERM_MF_DIRECT	GO:0004725~protein tyrosine phosphatase activity	5	1.5384615384615385	0.07886324090085822	DUSP5, DUSP2, PTPRN2, PTEN, PTPN4	316	99	19304	3.0852832118654905	1.0	0.7790671177386584	0.7509564485419027
GOTERM_MF_DIRECT	GO:0097100~supercoiled DNA binding	2	0.6153846153846154	0.07897759440993272	HMGB2, TOP1	316	5	19304	24.435443037974682	1.0	0.7790671177386584	0.7509564485419027
GOTERM_MF_DIRECT	GO:0019956~chemokine binding	2	0.6153846153846154	0.07897759440993272	PLP2, FGF2	316	5	19304	24.435443037974682	1.0	0.7790671177386584	0.7509564485419027
GOTERM_MF_DIRECT	GO:0043425~bHLH transcription factor binding	3	0.9230769230769231	0.08077809052047039	SP1, LMO2, SIRT1	316	29	19304	6.319511130510694	1.0	0.7835474780485627	0.755275146366398
GOTERM_MF_DIRECT	GO:0046983~protein dimerization activity	7	2.1538461538461537	0.08322627387653432	MEF2A, MLXIP, SREBF1, STAT5B, MEF2C, ID4, E2F6	316	185	19304	2.311460827916524	1.0	0.7912138985924135	0.7626649434885636
GOTERM_MF_DIRECT	GO:0051721~protein phosphatase 2A binding	3	0.9230769230769231	0.08564686531154993	STRN, TP53, FOXO1	316	30	19304	6.108860759493671	1.0	0.7912138985924135	0.7626649434885636
GOTERM_MF_DIRECT	GO:0001965~G-protein alpha-subunit binding	3	0.9230769230769231	0.08564686531154993	RGS4, LPAR1, IGF1R	316	30	19304	6.108860759493671	1.0	0.7912138985924135	0.7626649434885636
GOTERM_MF_DIRECT	GO:0004713~protein tyrosine kinase activity	5	1.5384615384615385	0.09061335467681912	EPHB2, MET, HIPK3, FGFR2, IGF1R	316	104	19304	2.936952288218111	1.0	0.8240151940923239	0.7942826870889926
GOTERM_MF_DIRECT	GO:0001875~lipopolysaccharide immune receptor activity	2	0.6153846153846154	0.09401060429551428	SCARB1, PTAFR	316	6	19304	20.362869198312236	1.0	0.8290026015149895	0.7990901365118713
GOTERM_MF_DIRECT	GO:0010385~double-stranded methylated DNA binding	2	0.6153846153846154	0.09401060429551428	EGR1, WT1	316	6	19304	20.362869198312236	1.0	0.8290026015149895	0.7990901365118713
GOTERM_MF_DIRECT	GO:0071889~14-3-3 protein binding	3	0.9230769230769231	0.09563861801822082	PRKCE, DDIT4, TP53	316	32	19304	5.727056962025317	1.0	0.830771278904545	0.8007949956451027