{"text_format":"3","workbook":"xls","n_sheets":6,"sheets":["Figure 2","Figure 3","Figure 4","Figure 6","Figure 7","Figure 8"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Figure 2","index":0,"n_rows":64,"n_cols":6,"rows_kept":64,"flags":["formulas_cached_only"]}
["Table Analyzed","Figure 2A"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",5]
["F",20.75]
["R squared",0.8925]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",10.31,4,2.576]
["Residual (within columns)",1.242,10,0.1242]
["Total",11.55,14]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["Mock vs 0.5pg",-0.6583,2.288,"No","ns","-1.490 to 0.1733"]
["Mock vs 1pg",-1,3.476,"Yes","*","-1.832 to -0.1684"]
["Mock vs 2.5pg",-2.315,8.047,"Yes","***","-3.147 to -1.483"]
["Mock vs Medium",-0.135,0.4692,"No","ns","-0.9666 to 0.6966"]
[]
[]
["Table Analyzed","Figure 2B"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",5]
["F",164.5]
["R squared",0.985]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",55.6,4,13.9]
["Residual (within columns)",0.845,10,0.0845]
["Total",56.44,14]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["Mock vs 0.5pg",-2.4,10.11,"Yes","***","-3.086 to -1.714"]
["Mock vs 1pg",-3.1,13.06,"Yes","***","-3.786 to -2.414"]
["Mock vs 2.5pg",-5.3,22.33,"Yes","***","-5.986 to -4.614"]
["Mock vs Medium",-0.4,1.685,"No","ns","-1.086 to 0.2860"]
[]
[]
["Table Analyzed","Figure 2C"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",5]
["F",710.2]
["R squared",0.9965]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",125800,4,31450]
["Residual (within columns)",442.9,10,44.29]
["Total",126200,14]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["Mock vs 0.5pg",-73.33,13.5,"Yes","***","-89.04 to -57.62"]
["Mock vs 1pg",-177.7,32.7,"Yes","***","-193.4 to -162.0"]
["Mock vs 2.5pg",-222.7,40.98,"Yes","***","-238.4 to -207.0"]
["Mock vs Medium",1.5,0.2761,"No","ns","-14.21 to 17.21"]

{"sheet":"Figure 3","index":1,"n_rows":123,"n_cols":6,"rows_kept":123,"flags":["formulas_cached_only"]}
["Table Analyzed","Figure 3A - HIV-1"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",7]
["F",69.06]
["R squared",0.9673]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",12700,6,2117]
["Residual (within columns)",429.2,14,30.66]
["Total",13130,20]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["none vs cAPE",59.43,13.15,"Yes","***","46.27 to 72.60"]
["none vs SB203580",31.67,7.005,"Yes","***","18.50 to 44.83"]
["none vs SB202190",44,9.733,"Yes","***","30.83 to 57.17"]
["none vs Ag17",11.33,2.507,"No","ns","-1.834 to 24.50"]
["none vs JNK-I",-0.6667,0.1475,"No","ns","-13.83 to 12.50"]
["none vs Genistein",61.33,13.57,"Yes","***","48.17 to 74.50"]
[]
[]
["Table Analyzed","Figure 3A - Mock"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",7]
["F",51]
["R squared",0.9563]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",9745,6,1624]
["Residual (within columns)",445.8,14,31.85]
["Total",10190,20]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["None vs CAPE",59.5,12.91,"Yes","***","46.08 to 72.92"]
["None vs SB203580",27.33,5.932,"Yes","***","13.91 to 40.75"]
["None vs SB202190",43.33,9.405,"Yes","***","29.91 to 56.75"]
["None vs AG17",13.33,2.894,"No","ns","-0.08636 to 26.75"]
["None vs JNK-I",17.67,3.834,"Yes","**","4.247 to 31.09"]
["None vs Genistein",59.67,12.95,"Yes","***","46.25 to 73.09"]
[]
[]
["Table Analyzed","Figure 3A - Medium"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",7]
["F",50.12]
["R squared",0.9555]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",9832,6,1639]
["Residual (within columns)",457.7,14,32.69]
["Total",10290,20]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["Column A vs Column B",59.47,12.74,"Yes","***","45.87 to 73.06"]
["Column A vs Column C",31.67,6.783,"Yes","***","18.07 to 45.26"]
["Column A vs Column D",43.33,9.282,"Yes","***","29.74 to 56.93"]
["Column A vs Column E",16,3.427,"Yes","*","2.403 to 29.60"]
["Column A vs Column F",16,3.427,"Yes","*","2.403 to 29.60"]
["Column A vs Column G",61.33,13.14,"Yes","***","47.74 to 74.93"]
[]
[]
["Table Analyzed","Figure 3B"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",10]
["F",29.76]
["R squared",0.9305]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",2774,9,308.3]
["Residual (within columns)",207.1,20,10.36]
["Total",2981,29]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["medium vs HIV",-20,7.611,"Yes","***","-27.74 to -12.26"]
["medium vs PDTC/HIV",-2,0.7611,"No","ns","-9.742 to 5.742"]
["medium vs PDTC/medium",-0.5,0.1903,"No","ns","-8.242 to 7.242"]
["medium vs AG18/HIV",0,0,"No","ns","-7.742 to 7.742"]
["medium vs AG18/medium",-0.4,0.1522,"No","ns","-8.142 to 7.342"]
["medium vs U126/HIV",-20,7.611,"Yes","***","-27.74 to -12.26"]
["medium vs U126/medium",-8,3.044,"Yes","*","-15.74 to -0.2580"]
["medium vs Wortmanin/HIV",-27,10.28,"Yes","***","-34.74 to -19.26"]
["medium vs Wortmanin/medium",-10,3.806,"Yes","**","-17.74 to -2.258"]
[]
[]
["Table Analyzed","Figure 3C"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",9]
["F",616.4]
["R squared",0.9964]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",468.3,8,58.54]
["Residual (within columns)",1.71,18,0.09497]
["Total",470,26]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["mock vs HIV",-13.3,52.86,"Yes","***","-14.04 to -12.56"]
["mock vs medium",0.3433,1.364,"No","ns","-0.3952 to 1.082"]
["mock vs Cape/HIV",-1.5,5.961,"Yes","***","-2.239 to -0.7615"]
["mock vs Cape/mock",0.42,1.669,"No","ns","-0.3185 to 1.159"]
["mock vs Cape/medium",0.4933,1.961,"No","ns","-0.2452 to 1.232"]
["mock vs Genistein/HIV",-1.833,7.286,"Yes","***","-2.572 to -1.095"]
["mock vs Genistein/mock",-0.2833,1.126,"No","ns","-1.022 to 0.4552"]
["mock vs Genistein/medium",0.06667,0.2649,"No","ns","-0.6719 to 0.8052"]

{"sheet":"Figure 4","index":2,"n_rows":50,"n_cols":6,"rows_kept":50,"flags":["formulas_cached_only"]}
["Table Analyzed","Figure 4A"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",9]
["F",692.7]
["R squared",0.9968]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",0.1341,8,0.01677]
["Residual (within columns)",0.0004357,18,2.42e-05]
["Total",0.1346,26]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["mock vs Positive control",-0.1553,38.67,"Yes","***","-0.1671 to -0.1435"]
["mock vs Competitor",0.02717,6.763,"Yes","***","0.01538 to 0.03896"]
["mock vs IL-1 beta",-0.148,36.84,"Yes","***","-0.1598 to -0.1362"]
["mock vs HIV",-0.09567,23.82,"Yes","***","-0.1075 to -0.08388"]
["mock vs medium",0.015,3.734,"Yes","**","0.003210 to 0.02679"]
["mock vs Cape/HIV",0.005667,1.411,"No","ns","-0.006123 to 0.01746"]
["mock vs Cape/mock",0.001667,0.4149,"No","ns","-0.01012 to 0.01346"]
["mock vs Cape/medium",0.02167,5.394,"Yes","***","0.009877 to 0.03346"]
[]
[]
["Table Analyzed","Figure 4B"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",9]
["F",511.1]
["R squared",0.9956]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",6085,8,760.6]
["Residual (within columns)",26.79,18,1.488]
["Total",6112,26]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["mock vs HIV",-25.25,25.35,"Yes","***","-28.17 to -22.33"]
["mock vs medium",1.625,1.631,"No","ns","-1.298 to 4.548"]
["mock vs Ad-IkB/HIV+",17.52,17.59,"Yes","***","14.59 to 20.44"]
["mock vs Ad-IkB/mock",15.85,15.91,"Yes","***","12.93 to 18.77"]
["mock vs Ad-IkB/medium",18.07,18.14,"Yes","***","15.15 to 20.99"]
["mock vs Ad/HIV+",-15.08,15.14,"Yes","***","-18.01 to -12.16"]
["mock vs Ad/mock",15.42,15.48,"Yes","***","12.49 to 18.34"]
["mock vs Ad-medium",15.95,16.01,"Yes","***","13.03 to 18.87"]

{"sheet":"Figure 6","index":3,"n_rows":60,"n_cols":6,"rows_kept":60,"flags":["formulas_cached_only"]}
["Table Analyzed","Figure 6A"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",14]
["F",2374]
["R squared",0.9991]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",197200,13,15170]
["Residual (within columns)",178.9,28,6.39]
["Total",197400,41]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["1006bp/HIV vs 50bp/HIV",194.3,94.16,"Yes","***","188.2 to 200.5"]
["1006bp/HIV vs 50bp",199.3,96.58,"Yes","***","193.2 to 205.5"]
["1006bp/HIV vs 100bp/HIV",179,86.73,"Yes","***","172.8 to 185.2"]
["1006bp/HIV vs 100bp",185.3,89.8,"Yes","***","179.2 to 191.5"]
["1006bp/HIV vs 200bp/HIV",25.5,12.35,"Yes","***","19.33 to 31.67"]
["1006bp/HIV vs 200bp",64.33,31.17,"Yes","***","58.17 to 70.50"]
["1006bp/HIV vs 300bp/HIV",-2.417,1.171,"No","ns","-8.584 to 3.751"]
["1006bp/HIV vs 300bp",92.58,44.86,"Yes","***","86.42 to 98.75"]
["1006bp/HIV vs 600bp/HIV",54,26.16,"Yes","***","47.83 to 60.17"]
["1006bp/HIV vs 600bp",127.7,61.86,"Yes","***","121.5 to 133.8"]
["1006bp/HIV vs 875/HIV",97,47,"Yes","***","90.83 to 103.2"]
["1006bp/HIV vs 875",159,77.04,"Yes","***","152.8 to 165.2"]
["1006bp/HIV vs 1006bp",93,45.06,"Yes","***","86.83 to 99.17"]
[]
[]
["Table Analyzed","Figure 6B"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",14]
["F",118.8]
["R squared",0.9822]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",14910,13,1147]
["Residual (within columns)",270.3,28,9.653]
["Total",15180,41]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["CF/HIV vs C1/HIV",63.15,24.89,"Yes","***","55.57 to 70.73"]
["CF/HIV vs C1",63.15,24.89,"Yes","***","55.57 to 70.73"]
["CF/HIV vs C2/HIV",63,24.83,"Yes","***","55.42 to 70.58"]
["CF/HIV vs C2",62.8,24.76,"Yes","***","55.22 to 70.38"]
["CF/HIV vs C3/HIV",51.7,20.38,"Yes","***","44.12 to 59.28"]
["CF/HIV vs C3",59.7,23.53,"Yes","***","52.12 to 67.28"]
["CF/HIV vs C4/HIV",17.7,6.977,"Yes","***","10.12 to 25.28"]
["CF/HIV vs C4",50,19.71,"Yes","***","42.42 to 57.58"]
["CF/HIV vs C5/HIV",44.7,17.62,"Yes","***","37.12 to 52.28"]
["CF/HIV vs C5",58.9,23.22,"Yes","***","51.32 to 66.48"]
["CF/HIV vs C6/HIV",26.4,10.41,"Yes","***","18.82 to 33.98"]
["CF/HIV vs C6",57,22.47,"Yes","***","49.42 to 64.58"]
["CF/HIV vs CF",43.4,17.11,"Yes","***","35.82 to 50.98"]

{"sheet":"Figure 7","index":4,"n_rows":64,"n_cols":6,"rows_kept":64,"flags":["formulas_cached_only"]}
["Table Analyzed","Figure 7A"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",4]
["F",1180000]
["R squared",1]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",15370000,3,5123000]
["Residual (within columns)",34.72,8,4.341]
["Total",15370000,11]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["Mock vs 0.5 HIV",-296.8,174.5,"Yes","***","-301.7 to -291.9"]
["Mock vs 2.5 HIV",-2698,1586,"Yes","***","-2703 to -2693"]
["Mock vs Medium",-2.333,1.372,"No","ns","-7.232 to 2.565"]
[]
["Table Analyzed","Figure 7B"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",6]
["F",76.35]
["R squared",0.9695]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",3755,5,751.1]
["Residual (within columns)",118,12,9.837]
["Total",3873,17]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["mock vs HIV (1pg)",-33.5,13.08,"Yes","***","-40.93 to -26.07"]
["mock vs MoAb M-anti-H IL-6(10ug/ml)/HI",-0.5,0.1952,"No","ns","-7.930 to 6.930"]
["mock vs IgGM 10ug/ml/HIV",-22.1,8.63,"Yes","***","-29.53 to -14.67"]
["mock vs MoAb M-anti-H IL-6(10ng/ml)",5.36,2.093,"No","ns","-2.070 to 12.79"]
["mock vs IgGM 10ug/ml",2.2,0.8591,"No","ns","-5.230 to 9.630"]
[]
[]
["Table Analyzed","Figure 7C"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",6]
["F",1286]
["R squared",0.9981]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",5932,5,1186]
["Residual (within columns)",11.07,12,0.9222]
["Total",5943,17]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["medium vs IL-6 ",-25.04,31.94,"Yes","***","-27.32 to -22.77"]
["medium vs Ad-IkB/IL-6",15.29,19.5,"Yes","***","13.02 to 17.57"]
["medium vs Adenovirus-IkB",16.45,20.97,"Yes","***","14.17 to 18.72"]
["medium vs Ad/IL-6",-25.38,32.36,"Yes","***","-27.65 to -23.10"]
["medium vs Adenovirus",14.33,18.27,"Yes","***","12.05 to 16.60"]

{"sheet":"Figure 8","index":5,"n_rows":21,"n_cols":6,"rows_kept":21,"flags":["formulas_cached_only"]}
["Table Analyzed","Figure 8A"]
[]
["One-way analysis of variance"]
["P value","< 0.0001"]
["P value summary","***"]
["Are means signif. different? (P < 0.05)","Yes"]
["Number of groups",6]
["F",368]
["R squared",0.9935]
[]
["ANOVA Table","SS","df","MS"]
["Treatment (between columns)",18700,5,3741]
["Residual (within columns)",122,12,10.17]
["Total",18830,17]
[]
["Dunnett's Multiple Comparison Test","Mean Diff.","q","Significant? P < 0.05?","Summary","95% CI of diff"]
["Mock vs HIV-1 0.5pg",-41.7,16.02,"Yes","***","-49.25 to -34.15"]
["Mock vs HIV 1pg",-81,31.11,"Yes","***","-88.55 to -73.45"]
["Mock vs Mock + CAPE",4,1.537,"No","ns","-3.553 to 11.55"]
["Mock vs HIV (1pg) + CAPE",3,1.152,"No","ns","-4.553 to 10.55"]
["Mock vs IL-6pro/Cape/mock",3.4,1.306,"No","ns","-4.153 to 10.95"]