If you used this method, please cite the article: 

Jones DT, Buchan DW, Cozzetto D, Pontil M (2012) Psicov: precise structural
contact prediction using sparse inverse covariance estimation on large multiple se-
quence alignments. Bioinformatics 28: 184–190.

Software availability: http://bioinfadmin.cs.ucl.ac.uk/downloads/PSICOV/

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Step 1: download and install the software according to its manual.

Step 2: prepare the input files of PSICOV by opening the matlab file PSICOV_PrepareInput.m in the fold of PSICOV

Step 3: use the Linux command line to run the software.


cd /home/lowie/MatlabCode/Coevolution/PSICOV

./psicov -a -d 0.03 /home/lowie/EnsembleCoevolutionSystem/PSICOV/PR_psicov.selex > /home/lowie/EnsembleCoevolutionSystem/PSICOV/PR_psicov.matrix



