2017-11-27T17:06:19Z Mass action rate law for first order irreversible reactions

Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant.

k1*PRODUCT<substrate_i> 2017-11-29T15:16:08Z Mass action rate law for reversible reactions

Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products.

k1*PRODUCT<substrate_i>-k2*PRODUCT<product_j> 2018-01-24T16:54:18Z pH limit is the pH that defined the effect. Above: activates (or inhibits) , below inhibits (or activates) enhancer will potenciate the effect of departure from the pHlimit. The sign of enhancer determines if the reaction will be potenciated at pH higher than pH limit (sign +) or will potenciate at pH lower than pH limit (sign -) Notice that at pH = phlimit, the factor is 1. k then is the kinetics constant at the pHlimit substrate1 * substrate2 * k *(10^(pH-pHlimit))^enhancer 2018-01-24T16:54:18Z substrate1 * k *(10^(pH-pHlimit))^enhancer 2017-01-18T16:23:27Z Units are in millimolar. pmol/nl Adding HexA association dissociation and the reverse reaction. Controled by the pH Adding GM degradation, promoted by low pH and HexA, inhibited by cholesterol Adding chol removal in RabD endosomes 2018-04-04T15:17:59Z 2017-11-28T14:59:21Z 2017-11-28T17:18:32Z 2017-11-28T17:17:55Z 2018-02-21T09:27:51Z 2018-04-04T15:18:03Z 2018-04-04T15:17:35Z 2018-04-04T15:17:23Z 2017-11-27T17:03:45Z -log(<CN=Root,Model=LipidMetabolism,Vector=Compartments[compartment],Vector=Metabolites[proton],Reference=Concentration>*1e-3)/log(10) 2018-01-25T15:48:28Z 0.01*(10^(<CN=Root,Model=LipidMetabolism,Vector=Values[pH],Reference=Value>-6.7))^3 2018-01-27T18:21:35Z 2018-01-26T11:02:39Z 2018-01-26T12:59:17Z 2018-02-14T15:50:30Z 0.000001/(<CN=Root,Model=LipidMetabolism,Vector=Compartments[compartment],Vector=Metabolites[chol],Reference=Concentration>+0.00000001) 2017-11-28T15:02:35Z 2017-11-27T17:28:04Z 2018-01-31T11:33:41Z 2018-01-31T11:33:41Z 2018-02-14T15:44:51Z 2018-02-16T10:27:50Z <CN=Root,Model=LipidMetabolism,Vector=Values[kpH],Reference=InitialValue> <CN=Root,Model=LipidMetabolism,Vector=Values[pH],Reference=InitialValue> <CN=Root,Model=LipidMetabolism,Vector=Values[acidpH],Reference=InitialValue> <CN=Root,Model=LipidMetabolism,Vector=Values[pH],Reference=InitialValue> <CN=Root,Model=LipidMetabolism,Vector=Values[cholInhibition],Reference=InitialValue> <CN=Root,Model=LipidMetabolism,Vector=Values[pH],Reference=InitialValue> 0 6.02214179e+017 15657570882192462 0 0 0 0 4.5850265902257403 4.5193894834280823e-009 100 60221417900000.047 0 0 1000000 0.00020000000000000001 3 -1.5 Automatically generated report.