{"text_format":"3","workbook":"xls","n_sheets":11,"sheets":["Table S2 Liver Samples","Table S3 WD Specific Liver","Table S4 WD EarlySpecific Liver","Table S6 WD Adv vs Early Liver","Table S8 DMR Drug Enrichment","Table S9 Cell Specific Promoter","Table S11 Blood Samples","Table S12 WD Specific Blood","Table S13 Human-Mouse Overlap","Table S14 WD Hep vs Neuro Blood","Table S15 Adaboost WD HvN Blood"],"not_rendered":{"external_links":1,"defined_names":9},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table S2 Liver Samples","index":0,"n_rows":22,"n_cols":17,"rows_kept":22,"flags":["formulas_cached_only"]}
["Sequencing ID","Sex","Age","BMI","Diagnosis","Fibrosis","Steatosis","Inflammation","Cu (µg/g)","Current treatment","Coverage (x)","Mappability","mCG","mCHG","mCHH","ConvEff","PCR Duplicates"]
["VMDK001C","Male",55,23,"Healthy –  percutaneous  biopsy",0,0,1,null,null,1.3,{"v":0.715,"d":"71.5%"},{"v":0.744,"d":"74.4%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.2208,"d":"22.1%"}]
["VMDK001D","Female",67,58.7,"Healthy –  bariatric surgery",0,0,0,null,null,1.5,{"v":0.736,"d":"73.6%"},{"v":0.717,"d":"71.7%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.2564,"d":"25.6%"}]
["VMDK004C","Male",46,42,"Healthy –  bariatric surgery",0,0,0,null,null,1.3,{"v":0.725,"d":"72.5%"},{"v":0.739,"d":"73.9%"},{"v":0.016,"d":"1.6%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.188,"d":"18.8%"}]
["VMDK005C","Female",44,38,"Healthy –  bariatric surgery",0,0,0,null,null,1.1,{"v":0.706,"d":"70.6%"},{"v":0.763,"d":"76.3%"},{"v":0.018,"d":"1.8%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.1762,"d":"17.6%"}]
["VMDK006B","Male",57,35,"Healthy –  bariatric surgery",0,0,0,null,null,{"v":2,"d":"2.0"},{"v":0.738,"d":"73.8%"},{"v":0.755,"d":"75.5%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.2883,"d":"28.8%"}]
["VMDK006C","Female",23,41,"Healthy –  bariatric surgery",0,0,0,null,null,{"v":2,"d":"2.0"},{"v":0.731,"d":"73.1%"},{"v":0.727,"d":"72.7%"},{"v":0.016,"d":"1.6%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.2847,"d":"28.5%"}]
["VMDK002C","Male",72,32,"NAFLD – percutaneous biopsy",4,1,1,null,null,1.1,{"v":0.733,"d":"73.3%"},{"v":0.743,"d":"74.3%"},{"v":0.018,"d":"1.8%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.1814,"d":"18.1%"}]
["VMDK006A","Male",22,35,"NAFLD – percutaneous biopsy",1,3,0,null,null,1.4,{"v":0.729,"d":"72.9%"},{"v":0.74,"d":"74.0%"},{"v":0.017,"d":"1.7%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.2612,"d":"26.1%"}]
["VMDK002D","Female",60,51,"NAFLD – percutaneous biopsy",1,1,2,null,null,1.9,{"v":0.739,"d":"73.9%"},{"v":0.736,"d":"73.6%"},{"v":0.018,"d":"1.8%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.2627,"d":"26.3%"}]
["VMDK003C","Female",32,46,"NAFLD – percutaneous biopsy",1,1,1,null,null,1.8,{"v":0.745,"d":"74.5%"},{"v":0.754,"d":"75.4%"},{"v":0.019,"d":"1.9%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.2687,"d":"26.9%"}]
["VMDK003D","Female",52,36,"NAFLD – percutaneous biopsy",1,1,1,null,null,1.3,{"v":0.728,"d":"72.8%"},{"v":0.744,"d":"74.4%"},{"v":0.018,"d":"1.8%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.2451,"d":"24.5%"}]
["VMDK001B","Male",22,30,"WD – percutaneous biopsy",3,2,1,645,"Trientine",1.7,{"v":0.735,"d":"73.5%"},{"v":0.736,"d":"73.6%"},{"v":0.018,"d":"1.8%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.2317,"d":"23.2%"}]
["VMDK002B","Female",50,32,"WD – percutaneous biopsy",1,0,1,250,"Trientine and zinc",1.1,{"v":0.721,"d":"72.1%"},{"v":0.739,"d":"73.9%"},{"v":0.018,"d":"1.8%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.1831,"d":"18.3%"}]
["VMDK003B","Male",46,34,"WD – percutaneous biopsy",4,1,0,41,"Zinc acetate",1.2,{"v":0.724,"d":"72.4%"},{"v":0.75,"d":"75.0%"},{"v":0.019,"d":"1.9%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.2066,"d":"20.7%"}]
["VMDK004B","Female",40,28,"WD – percutaneous biopsy",0,1,1,646,"Zinc acetate",1.3,{"v":0.725,"d":"72.5%"},{"v":0.737,"d":"73.7%"},{"v":0.018,"d":"1.8%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.2297,"d":"23.0%"}]
["VMDK005B","Female",36,34,"WD – percutaneous biopsy",0.5,0,1,631,"Zinc sulfate",1.1,{"v":0.705,"d":"70.5%"},{"v":0.732,"d":"73.2%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.1853,"d":"18.5%"}]
["VMDK005A","Male",45,"N/A","WD – liver transplant",4,"N/A","N/A",null,null,{"v":1,"d":"1.0"},{"v":0.705,"d":"70.5%"},{"v":0.752,"d":"75.2%"},{"v":0.016,"d":"1.6%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.2304,"d":"23.0%"}]
["VMDK004A","Female",41,"N/A","WD – liver transplant",4,"N/A","N/A",null,null,1.5,{"v":0.739,"d":"73.9%"},{"v":0.745,"d":"74.5%"},{"v":0.015,"d":"1.5%"},{"v":0.011,"d":"1.1%"},{"v":0.989,"d":"98.9%"},{"v":0.2852,"d":"28.5%"}]
["VMDK003A","Male",31,"N/A","WD – liver transplant",4,"N/A","N/A",null,null,1.2,{"v":0.749,"d":"74.9%"},{"v":0.753,"d":"75.3%"},{"v":0.016,"d":"1.6%"},{"v":0.011,"d":"1.1%"},{"v":0.989,"d":"98.9%"},{"v":0.1945,"d":"19.5%"}]
["VMDK002A","Female",23,"N/A","WD – liver transplant",0,"N/A",4,null,null,1.3,{"v":0.762,"d":"76.2%"},{"v":0.744,"d":"74.4%"},{"v":0.017,"d":"1.7%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.2371,"d":"23.7%"}]
["VMDK001A","Male",38,"N/A","WD – liver transplant",4,"N/A","N/A",null,null,1.1,{"v":0.714,"d":"71.4%"},{"v":0.749,"d":"74.9%"},{"v":0.018,"d":"1.8%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.1943,"d":"19.4%"}]

{"sheet":"Table S3 WD Specific Liver","index":1,"n_rows":1840,"n_cols":40,"rows_kept":1840,"flags":["formulas_cached_only"]}
["DMR_Set","chr","start","end","CpGs","meanReads","width","areaStat","HC_mean","WD_mean","meanDiff","direction","confIntL","confIntR","tstat","pValue","FWER","Rel_FWER","Genome_Significant","BMI_estimate","BMI_pvalue","BMI_pAdj","FibrosisStage_estimate","FibrosisStage_pvalue","FibrosisStage_pAdj","Steatosis_estimate","Steatosis_pvalue","Steatosis_pAdj","InflammationGrade_estimate","InflammationGrade_pvalue","InflammationGrade_pAdj","sex_estimate","sex_pvalue","sex_pAdj","age_estimate","age_pvalue","age_pAdj","gene_name","distanceToTSS","position"]
["WD_Specific_Liver","chr1",998008,998500,43,{"v":136.875,"d":"137"},492,{"v":132.434204579879,"d":"132.43"},{"v":0.316830229389487,"d":"0.32"},{"v":0.49669577164157,"d":"0.50"},{"v":0.179865542252083,"d":"0.18"},"hyper",{"v":0.0422429884397194,"d":"0.04"},{"v":0.317470344893614,"d":"0.32"},{"v":2.8320303991159,"d":"2.83"},{"v":0.0144809165324131,"d":"1.45E-02"},273,0.273,false,{"v":-0.004458741819588,"d":"-0.004"},{"v":0.302229565400824,"d":"0.302"},{"v":1,"d":"1.000"},{"v":0.0451086179507545,"d":"0.045"},{"v":0.0267111419098764,"d":"0.027"},{"v":1,"d":"1.000"},{"v":-0.0163617486338798,"d":"-0.016"},{"v":0.716001121861249,"d":"0.716"},{"v":1,"d":"1.000"},{"v":0.0540828571428571,"d":"0.054"},{"v":0.149814149608582,"d":"0.150"},{"v":1,"d":"1.000"},{"v":0.0636090909090909,"d":"0.064"},{"v":0.383963679145183,"d":"0.384"},{"v":1,"d":"1.000"},{"v":0.000157403365882195,"d":"0.000"},{"v":0.951459768414811,"d":"0.951"},{"v":1,"d":"1.000"},"PERM1, HES4","-15891, 1672","upstream, downstream"]
["WD_Specific_Liver","chr1",1004716,1005385,7,{"v":20.8125,"d":"21"},669,{"v":-22.778882608947,"d":"-22.78"},{"v":0.493395916176755,"d":"0.49"},{"v":0.332482163149501,"d":"0.33"},{"v":-0.160913753027254,"d":"-0.16"},"hypo",{"v":-0.250099187140462,"d":"-0.25"},{"v":-0.0717408128595384,"d":"-0.07"},{"v":-3.87654990180483,"d":"-3.88"},{"v":0.00172868043227196,"d":"1.73E-03"},1000,{"v":1,"d":"1.000"},false,{"v":0.00759053252336486,"d":"0.008"},{"v":0.0282604755268094,"d":"0.028"},{"v":1,"d":"1.000"},{"v":-0.051112629070691,"d":"-0.051"},{"v":0.00153182461227774,"d":"0.002"},{"v":1,"d":"1.000"},{"v":-0.0164994535519126,"d":"-0.016"},{"v":0.635180940911885,"d":"0.635"},{"v":1,"d":"1.000"},{"v":-0.0228385714285714,"d":"-0.023"},{"v":0.458452794706797,"d":"0.458"},{"v":1,"d":"1.000"},{"v":0.0626872727272727,"d":"0.063"},{"v":0.315903423085047,"d":"0.316"},{"v":1,"d":"1.000"},{"v":0.00248576474823381,"d":"0.002"},{"v":0.246957182820358,"d":"0.247"},{"v":1,"d":"1.000"},"HES4, ISG15","-4544, -8081","upstream, upstream"]
["WD_Specific_Liver","chr1",1158214,1158922,12,{"v":39.4375,"d":"39"},708,{"v":-61.314138719728,"d":"-61.31"},{"v":0.654965285999064,"d":"0.65"},{"v":0.426748363985835,"d":"0.43"},{"v":-0.228216922013229,"d":"-0.23"},"hypo",{"v":-0.316342368999663,"d":"-0.32"},{"v":-0.14011096433367,"d":"-0.14"},{"v":-5.57532262125353,"d":"-5.58"},{"v":7.86434938451021e-05,"d":"7.86E-05"},994,0.994,false,{"v":0.00141311845098461,"d":"0.001"},{"v":0.700092606591302,"d":"0.700"},{"v":1,"d":"1.000"},{"v":-0.0533210087370929,"d":"-0.053"},{"v":0.00211661292709888,"d":"0.002"},{"v":1,"d":"1.000"},{"v":-0.0244939890710382,"d":"-0.024"},{"v":0.43728904478508,"d":"0.437"},{"v":1,"d":"1.000"},{"v":-0.0772196428571428,"d":"-0.077"},{"v":0.00498242826600811,"d":"0.005"},{"v":1,"d":"1.000"},{"v":-0.0263672727272727,"d":"-0.026"},{"v":0.694243571983161,"d":"0.694"},{"v":1,"d":"1.000"},{"v":0.00135937542186023,"d":"0.001"},{"v":0.558475926512469,"d":"0.558"},{"v":1,"d":"1.000"},"LINC01342, MIR200B","21198, -8181","downstream, upstream"]
["WD_Specific_Liver","chr1",1173935,1174461,18,{"v":55.375,"d":"55"},526,{"v":73.4034710591967,"d":"73.40"},{"v":0.289560453955264,"d":"0.29"},{"v":0.539935866733607,"d":"0.54"},{"v":0.250375412778343,"d":"0.25"},"hyper",{"v":0.100712708678557,"d":"0.10"},{"v":0.400067291321443,"d":"0.40"},{"v":3.66839488041345,"d":"3.67"},{"v":0.00352000494032458,"d":"3.52E-03"},921,0.921,false,{"v":-0.0028386212121511,"d":"-0.003"},{"v":0.602404232188296,"d":"0.602"},{"v":1,"d":"1.000"},{"v":0.0584851469420175,"d":"0.058"},{"v":0.0089520181340923,"d":"0.009"},{"v":1,"d":"1.000"},{"v":-0.0218672131147541,"d":"-0.022"},{"v":0.655281314232147,"d":"0.655"},{"v":1,"d":"1.000"},{"v":0.0358960714285714,"d":"0.036"},{"v":0.363794694918515,"d":"0.364"},{"v":1,"d":"1.000"},{"v":0.0566881818181818,"d":"0.057"},{"v":0.496518724197268,"d":"0.497"},{"v":1,"d":"1.000"},{"v":0.000217360392386264,"d":"0.000"},{"v":0.940514813769172,"d":"0.941"},{"v":1,"d":"1.000"},"TTLL10",30,"gene_body"]
["WD_Specific_Liver","chr1",1208371,1209068,23,{"v":73.1875,"d":"73"},697,{"v":-66.5490193869731,"d":"-66.55"},{"v":0.499092989092259,"d":"0.50"},{"v":0.348418166366913,"d":"0.35"},{"v":-0.150674822725345,"d":"-0.15"},"hypo",{"v":-0.249905423309593,"d":"-0.25"},{"v":-0.0514545766904071,"d":"-0.05"},{"v":-3.2674171785105,"d":"-3.27"},{"v":0.00583536630975379,"d":"5.84E-03"},950,{"v":0.95,"d":"0.950"},false,{"v":0.0047923142106852,"d":"0.005"},{"v":0.145661849940135,"d":"0.146"},{"v":1,"d":"1.000"},{"v":-0.0372319698173153,"d":"-0.037"},{"v":0.0219699306578697,"d":"0.022"},{"v":1,"d":"1.000"},{"v":0.0219590163934426,"d":"0.022"},{"v":0.50314826846378,"d":"0.503"},{"v":1,"d":"1.000"},{"v":-0.0648567857142857,"d":"-0.065"},{"v":0.0385825468848922,"d":"0.039"},{"v":1,"d":"1.000"},{"v":-0.03319,"d":"-0.033"},{"v":0.570000574301592,"d":"0.570"},{"v":1,"d":"1.000"},{"v":0.000614251001214959,"d":"0.001"},{"v":0.766762839676029,"d":"0.767"},{"v":1,"d":"1.000"},"TNFRSF18",-1662,"upstream"]
["WD_Specific_Liver","chr1",1213298,1213958,27,94,660,{"v":-99.0917246772194,"d":"-99.09"},{"v":0.714722371555429,"d":"0.71"},{"v":0.517863122675967,"d":"0.52"},{"v":-0.196859248879462,"d":"-0.20"},"hypo",{"v":-0.313743160541483,"d":"-0.31"},{"v":-0.0800368394585174,"d":"-0.08"},{"v":-3.65475444964296,"d":"-3.65"},{"v":0.00309092571585634,"d":"3.09E-03"},600,{"v":0.6,"d":"0.600"},false,{"v":0.000760174094556385,"d":"0.001"},{"v":0.842146202727139,"d":"0.842"},{"v":1,"d":"1.000"},{"v":-0.0570546465448769,"d":"-0.057"},{"v":0.000158362255603973,"d":"0.000"},{"v":0.291228188055706,"d":"0.291"},{"v":-0.0123153005464481,"d":"-0.012"},{"v":0.742258154595357,"d":"0.742"},{"v":1,"d":"1.000"},{"v":-0.0240992857142857,"d":"-0.024"},{"v":0.439824411477547,"d":"0.440"},{"v":1,"d":"1.000"},{"v":0.00402454545454545,"d":"0.004"},{"v":0.947278843455502,"d":"0.947"},{"v":1,"d":"1.000"},{"v":0.000598911038113668,"d":"0.001"},{"v":0.780765692587358,"d":"0.781"},{"v":1,"d":"1.000"},"TNFRSF4",210,"gene_body"]
["WD_Specific_Liver","chr1",1238345,1238833,11,{"v":36.375,"d":"36"},488,{"v":-26.6782826490748,"d":"-26.68"},{"v":0.748688492054241,"d":"0.75"},{"v":0.613752577167729,"d":"0.61"},{"v":-0.134935914886512,"d":"-0.13"},"hypo",{"v":-0.249364933033064,"d":"-0.25"},{"v":-0.0205217336336028,"d":"-0.02"},{"v":-2.53941325737925,"d":"-2.54"},{"v":0.0241845276340619,"d":"2.42E-02"},1000,{"v":1,"d":"1.000"},false,{"v":0.00173256440255617,"d":"0.002"},{"v":0.59863645986448,"d":"0.599"},{"v":1,"d":"1.000"},{"v":-0.0516837966640191,"d":"-0.052"},{"v":0.000391061842971837,"d":"0.000"},{"v":0.719162729225208,"d":"0.719"},{"v":-0.0185027322404372,"d":"-0.019"},{"v":0.499732397180947,"d":"0.500"},{"v":1,"d":"1.000"},{"v":0.00689821428571427,"d":"0.007"},{"v":0.757342740451878,"d":"0.757"},{"v":1,"d":"1.000"},{"v":0.0222472727272728,"d":"0.022"},{"v":0.701969390754264,"d":"0.702"},{"v":1,"d":"1.000"},{"v":0.00151434887278945,"d":"0.002"},{"v":0.453846246705227,"d":"0.454"},{"v":1,"d":"1.000"},"SDF4, FAM132A","-6278, 7889","upstream, downstream"]
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{"sheet":"Table S4 WD EarlySpecific Liver","index":2,"n_rows":195,"n_cols":40,"rows_kept":195,"flags":["formulas_cached_only"]}
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{"sheet":"Table S6 WD Adv vs Early Liver","index":3,"n_rows":2459,"n_cols":40,"rows_kept":2459,"flags":["formulas_cached_only"]}
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{"sheet":"Table S8 DMR Drug Enrichment","index":4,"n_rows":76,"n_cols":7,"rows_kept":76,"flags":["formulas_cached_only"]}
["DMRset","Drug","intersection","oddsRatio","pvalue","qvalue","Genes"]
["Liver_All","MELPHALAN",5,{"v":13.6122022269354,"d":"13.6"},{"v":0.000652814513865029,"d":"6.5E-04"},{"v":1,"d":"1.00"},"FANCC, GSTP1, MGMT, OPLAH, PLAT"]
["Liver_All","ICATIBANT",3,"Inf",{"v":0.00130218279262046,"d":"1.3E-03"},{"v":1,"d":"1.00"},"ANPEP, BDKRB1, BDKRB2"]
["Liver_All","IRINOTECAN",9,{"v":3.87203727661081,"d":"3.9"},{"v":0.00217505611827431,"d":"2.2E-03"},{"v":1,"d":"1.00"},"AKT1, EGFR, GSTP1, ISG15, MGMT, RUNX3, SMAD4, TOP1MT, UGT1A1"]
["Liver_All","ISOTRETINOIN",5,{"v":6.80634396835588,"d":"6.8"},{"v":0.00406099730468771,"d":"4.1E-03"},{"v":1,"d":"1.00"},"BCL2, RARA, STAT2, TGFB1, TGM2"]
["Liver_All","ISOPROTERENOL SULFATE",3,{"v":24.4829664730723,"d":"24.5"},{"v":0.00478243399174993,"d":"4.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3, SMYD2"]
["Liver_All","ANTAZOLINE HYDROCHLORIDE",3,{"v":24.4829664730723,"d":"24.5"},{"v":0.00478243399174993,"d":"4.8E-03"},{"v":1,"d":"1.00"},"COL18A1, IGF2, LAMA5"]
["Liver_Hyper","NIACIN",4,{"v":15.2780113900104,"d":"15.3"},{"v":0.000819287098997637,"d":"8.2E-04"},{"v":1,"d":"1.00"},"DGAT2, DRD1, NNMT, QPRT"]
["Liver_Hyper","ISOPROTERENOL SULFATE",3,{"v":45.7861020413273,"d":"45.8"},{"v":0.000888507476049075,"d":"8.9E-04"},{"v":1,"d":"1.00"},"ADRB2, ADRB3, SMYD2"]
["Liver_Hyper","ALVOCIDIB",5,{"v":8.4940887640326,"d":"8.5"},{"v":0.00109984717374554,"d":"1.1E-03"},{"v":1,"d":"1.00"},"CDK10, CDK3, CDK5, CDK9, EGFR"]
["Liver_Hyper","TG-02",4,{"v":12.2228778382388,"d":"12.2"},{"v":0.00140290146112944,"d":"1.4E-03"},{"v":1,"d":"1.00"},"CDK3, CDK5, CDK9, TYK2"]
["Liver_Hyper","PHENYLPROPANOLAMINE",3,{"v":22.9007775033317,"d":"22.9"},{"v":0.00211923676512788,"d":"2.1E-03"},{"v":1,"d":"1.00"},"ADRA2A, ADRB2, DRD1"]
["Liver_Hyper","NORADRENALINE",4,{"v":10.1859453165143,"d":"10.2"},{"v":0.00222455980272293,"d":"2.2E-03"},{"v":1,"d":"1.00"},"ADRA2A, ADRB2, ADRB3, DRD1"]
["Liver_Hyper","RISPERIDONE",8,{"v":3.9503202218,"d":"4.0"},{"v":0.00224249282531992,"d":"2.2E-03"},{"v":1,"d":"1.00"},"ADRA2A, ADRB2, AKT1, DRD1, DRD4, FASN, SERPINA3, SLC1A1"]
["Liver_Hyper","PYRIDOXAL PHOSPHATE",9,{"v":3.44486967232021,"d":"3.4"},{"v":0.00271864521738556,"d":"2.7E-03"},{"v":1,"d":"1.00"},"ALAS1, CSAD, GCAT, GPT, MOCOS, OAT, PYGB, SGPL1, SHMT2"]
["Liver_Hyper","SOLABEGRON",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","MIRABEGRON",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","CARAZOLOL",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","ARFORMOTEROL",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, UGT1A1"]
["Liver_Hyper","CHEMBL198059",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","CHEMBL1326499",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","CGP-12177",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","ABEDITEROL",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, ADRB3"]
["Liver_Hyper","PROCATEROL",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ADRB2, EGFR"]
["Liver_Hyper","EZETIMIBE",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"ANPEP, NPC1L1"]
["Liver_Hyper","CHEMBL220050",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"F10, F2"]
["Liver_Hyper","CHEMBL391737",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"F10, F2"]
["Liver_Hyper","CHEMBL391640",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"F10, F2"]
["Liver_Hyper","CHEMBL189938",2,"Inf",{"v":0.00378742952187558,"d":"3.8E-03"},{"v":1,"d":"1.00"},"NR1H3, RXRA"]
["Liver_Hyper","HEPARIN",6,{"v":4.58758217228364,"d":"4.6"},{"v":0.00426842675431406,"d":"4.3E-03"},{"v":1,"d":"1.00"},"APOB, F10, F2, SDC1, SERPINA5, TGM2"]
["Liver_Hyper","MK-2206",4,{"v":7.63795436589285,"d":"7.6"},{"v":0.00474807262431225,"d":"4.7E-03"},{"v":1,"d":"1.00"},"AKT1, CCNE1, EGFR, MPL"]
["Liver_Hypo","BUSULFAN",4,{"v":10.8809603963466,"d":"10.9"},{"v":0.00176823603471173,"d":"1.8E-03"},{"v":1,"d":"1.00"},"BCR, GSTP1, ITGAL, THPO"]
["Liver_Hypo","ARSENIC TRIOXIDE",6,{"v":5.15927560285482,"d":"5.2"},{"v":0.00253784062035803,"d":"2.5E-03"},{"v":1,"d":"1.00"},"AKT1, CCND1, MAPK3, PML, RARA, SMO"]
["Liver_Hypo","EXATECAN MESYLATE",2,"Inf",{"v":0.00334602554739523,"d":"3.3E-03"},{"v":1,"d":"1.00"},"GSTP1, MGMT"]
["Liver_Hypo","BENZYLCYSTEINE",2,"Inf",{"v":0.00334602554739523,"d":"3.3E-03"},{"v":1,"d":"1.00"},"MGMT, SLC1A5"]
["Liver_Hypo","VISMODEGIB",2,"Inf",{"v":0.00334602554739523,"d":"3.3E-03"},{"v":1,"d":"1.00"},"PTCH1, SMO"]
["Liver_Hypo","CHEMBL288436",2,"Inf",{"v":0.00334602554739523,"d":"3.3E-03"},{"v":1,"d":"1.00"},"RARA, RXRA"]
["Liver_Hypo","TAZAROTENE",3,{"v":16.3103093911369,"d":"16.3"},{"v":0.0033873565050288,"d":"3.4E-03"},{"v":1,"d":"1.00"},"BCL2, PML, RARA"]
["Liver_Hypo","N-METHYL-N-NITROSUREA",3,{"v":16.3103093911369,"d":"16.3"},{"v":0.0033873565050288,"d":"3.4E-03"},{"v":1,"d":"1.00"},"MAPK3, MGMT, RARA"]
["Liver_Early_All","BEPRIDIL",4,{"v":19.4118952870837,"d":"19.4"},{"v":0.000118028868876617,"d":"1.2E-04"},{"v":0.873059543080339,"d":"0.87"},"ATP1A1, CACNA1H, TNNC1, VIPR2"]
["Liver_Early_All","TROGLITAZONE",3,{"v":14.5198430185741,"d":"14.5"},{"v":0.00182300207137371,"d":"1.8E-03"},{"v":1,"d":"1.00"},"CCND1, SERPINE1, SLC29A1"]
["Liver_Early_All","CHLORPROMAZINE",3,{"v":11.2877437677341,"d":"11.3"},{"v":0.00341431478941923,"d":"3.4E-03"},{"v":1,"d":"1.00"},"ADRA2A, CYP1A2, SERPINA3"]
["Liver_Early_All","LURASIDONE",2,{"v":27.0166857181217,"d":"27.0"},{"v":0.00428610542717605,"d":"4.3E-03"},{"v":1,"d":"1.00"},"ADRA2A, SERPINA3"]
["Liver_Early_All","URIDINE",2,{"v":27.0166857181217,"d":"27.0"},{"v":0.00428610542717605,"d":"4.3E-03"},{"v":1,"d":"1.00"},"SERPINE1, SLC29A1"]
["Liver_Early_Hyper","CHLORPROMAZINE",3,{"v":17.9299293960827,"d":"17.9"},{"v":0.000940678945672601,"d":"9.4E-04"},{"v":0.830026234470998,"d":"0.83"},"ADRA2A, CYP1A2, SERPINA3"]
["Liver_Early_Hyper","PICTILISIB",3,{"v":15.3628032865555,"d":"15.4"},{"v":0.0014023393774215,"d":"1.4E-03"},{"v":0.830026234470998,"d":"0.83"},"MPL, PIK3R5, PIK3R6"]
["Liver_Early_Hyper","LURASIDONE",2,{"v":42.7827026483266,"d":"42.8"},{"v":0.00176397183366501,"d":"1.8E-03"},{"v":0.830026234470998,"d":"0.83"},"ADRA2A, SERPINA3"]
["Liver_Early_Hyper","URIDINE",2,{"v":42.7827026483266,"d":"42.8"},{"v":0.00176397183366501,"d":"1.8E-03"},{"v":0.830026234470998,"d":"0.83"},"SERPINE1, SLC29A1"]
["Liver_Early_Hyper","DACTOLISIB",3,{"v":13.4355532929134,"d":"13.4"},{"v":0.00198533321909172,"d":"2.0E-03"},{"v":0.830026234470998,"d":"0.83"},"MPL, PIK3R5, PIK3R6"]
["Liver_Early_Hyper","BUPARLISIB HYDROCHLORIDE",2,{"v":30.5918471209016,"d":"30.6"},{"v":0.00298694826521367,"d":"3.0E-03"},{"v":0.830026234470998,"d":"0.83"},"PIK3R5, PIK3R6"]
["Liver_Early_Hyper","UROKINASE",2,{"v":26.7496443945761,"d":"26.7"},{"v":0.00371079671182164,"d":"3.7E-03"},{"v":0.830026234470998,"d":"0.83"},"SERPINA5, SERPINE1"]
["Liver_Early_Hyper","ZSTK-474",2,{"v":23.7875257125785,"d":"23.8"},{"v":0.00450763569203559,"d":"4.5E-03"},{"v":0.830026234470998,"d":"0.83"},"MPL, PIK3R5"]
["Liver_Early_Hyper","DROTRECOGIN ALFA (ACTIVATED)",2,{"v":23.7875257125785,"d":"23.8"},{"v":0.00450763569203559,"d":"4.5E-03"},{"v":0.830026234470998,"d":"0.83"},"SERPINA5, SERPINE1"]
["Liver_Early_Hypo","BEPRIDIL",2,{"v":22.9040442720489,"d":"22.9"},{"v":0.00433916481501315,"d":"4.3E-03"},{"v":1,"d":"1.00"},"ATP1A1, VIPR2"]
["Liver_Early_Hypo","RALFINAMIDE",2,{"v":22.9040442720489,"d":"22.9"},{"v":0.00433916481501315,"d":"4.3E-03"},{"v":1,"d":"1.00"},"GRIN1, SCN8A"]
["Liver_Early_Hypo","ORPHENADRINE (CHLORIDE)",2,{"v":21.565074187992,"d":"21.6"},{"v":0.00483225901201858,"d":"4.8E-03"},{"v":1,"d":"1.00"},"GRIN1, SCN8A"]
["Liver_Early_Hypo","ORPHENADRINE CITRATE",2,{"v":21.565074187992,"d":"21.6"},{"v":0.00483225901201858,"d":"4.8E-03"},{"v":1,"d":"1.00"},"GRIN1, SCN8A"]
["Liver_Prog_Hyper","FLUFENAMIC ACID",8,{"v":4.10243717477498,"d":"4.1"},{"v":0.00230818645921846,"d":"2.3E-03"},{"v":1,"d":"1.00"},"C1R, C8G, GJB2, GJB6, GJC2, GJD3, PKD2L1, TRPM5"]
["Liver_Prog_Hyper","SB-203580",3,{"v":32.2403359999696,"d":"32.2"},{"v":0.00231336969944385,"d":"2.3E-03"},{"v":1,"d":"1.00"},"GAK, MAPK1, MAPK11"]
["Liver_Prog_Hyper","CHEMBL306380",4,{"v":10.753548480741,"d":"10.8"},{"v":0.00277947681462365,"d":"2.8E-03"},{"v":1,"d":"1.00"},"CSK, EGFR, FYN, RET"]
["Liver_Prog_Hyper","OCTANOL",6,{"v":4.96652572598504,"d":"5.0"},{"v":0.0038982932367172,"d":"3.9E-03"},{"v":1,"d":"1.00"},"C1R, C8G, GJB2, GJB6, GJC2, GJD3"]
["Liver_Prog_Hyper","DOVITINIB",6,{"v":4.96652572598504,"d":"5.0"},{"v":0.0038982932367172,"d":"3.9E-03"},{"v":1,"d":"1.00"},"CSF1R, EGFR, FGF3, FGFR3, PDGFRB, RET"]
["Liver_Prog_Hypo","CHEMBL306380",4,{"v":12.3453273178569,"d":"12.3"},{"v":0.00173171044726105,"d":"1.7E-03"},{"v":1,"d":"1.00"},"CSK, EGFR, FYN, RET"]
["Liver_Prog_Hypo","ISRADIPINE",4,{"v":9.87658238374586,"d":"9.9"},{"v":0.00293229633739877,"d":"2.9E-03"},{"v":1,"d":"1.00"},"CACNA1D, CACNA1H, CACNA2D2, NR1I2"]
["Liver_Prog_Hypo","ERISMODEGIB",3,{"v":18.5028557941449,"d":"18.5"},{"v":0.00376194825632541,"d":"3.8E-03"},{"v":1,"d":"1.00"},"EGFR, PTCH1, SMO"]
["Liver_Prog_Hypo","BEXAROTENE",3,{"v":18.5028557941449,"d":"18.5"},{"v":0.00376194825632541,"d":"3.8E-03"},{"v":1,"d":"1.00"},"MAPK8, NR1I2, RXRA"]
["Liver_Prog_Hypo","BUSULFAN",4,{"v":8.22999315575026,"d":"8.2"},{"v":0.00459825641589967,"d":"4.6E-03"},{"v":1,"d":"1.00"},"BCR, CLCN6, GSTP1, THPO"]
["Blood_All","DASATINIB",5,{"v":7.97831569339395,"d":"8.0"},{"v":0.000700333646037749,"d":"7.0E-04"},{"v":1,"d":"1.00"},"CSF3R, EPHA2, LCK, SIK3, SRC"]
["Blood_All","DORSOMORPHIN",3,{"v":21.7926994304523,"d":"21.8"},{"v":0.000785010218340269,"d":"7.9E-04"},{"v":1,"d":"1.00"},"EPHA2, LCK, SRC"]
["Blood_All","APABETALONE",2,{"v":101.677541934286,"d":"101.7"},{"v":0.00111082784746413,"d":"1.1E-03"},{"v":1,"d":"1.00"},"APOA1, BRD4"]
["Blood_All","COLFORSIN",2,{"v":50.7428395842919,"d":"50.7"},{"v":0.00219310962011756,"d":"2.2E-03"},{"v":1,"d":"1.00"},"ADCY5, GNAS"]
["Blood_All","VANDETANIB",4,{"v":7.55018804334371,"d":"7.6"},{"v":0.00289834717628888,"d":"2.9E-03"},{"v":1,"d":"1.00"},"EPHA2, EPHB4, SRC, VEGFA"]
["Blood_All","CHEMBL406845",2,{"v":33.834391598906,"d":"33.8"},{"v":0.00360829258557118,"d":"3.6E-03"},{"v":1,"d":"1.00"},"LCK, SRC"]
["Blood_All","TG100-801",3,{"v":10.1705805430909,"d":"10.2"},{"v":0.0047570583747912,"d":"4.8E-03"},{"v":1,"d":"1.00"},"EPHB4, LCK, SRC"]
["Blood_Hyper","VANDETANIB",4,{"v":10.3754156240598,"d":"10.4"},{"v":0.000935346216756751,"d":"9.4E-04"},{"v":1,"d":"1.00"},"EPHA2, EPHB4, SRC, VEGFA"]
["Blood_Hyper","DASATINIB",4,{"v":8.48500526292493,"d":"8.5"},{"v":0.00183614586149069,"d":"1.8E-03"},{"v":1,"d":"1.00"},"CSF3R, EPHA2, SIK3, SRC"]

{"sheet":"Table S9 Cell Specific Promoter","index":5,"n_rows":2459,"n_cols":40,"rows_kept":2459,"flags":["formulas_cached_only"]}
["chr","start","end","strand","entrezID","geneName","cellType","mean_Healthy","mean_NAFLD","mean_WD","mean_EarlyNAFLD","mean_EarlyWD","mean_AdvancedWD","sd_Healthy","sd_NAFLD","sd_WD","sd_EarlyNAFLD","sd_EarlyWD","sd_AdvancedWD","diff_NAFLDvsHealthy","diff_WDvsHealthy","diff_WDvsNAFLD","diff_EarlyNAFLDvsHealthy","diff_EarlyWDvsHealthy","diff_EarlyWDvsEarlyNAFLD","diff_AdvancedWDvsEarlyWD","pvalue_NAFLDvsHealthy","pvalue_WDvsHealthy","pvalue_WDvsNAFLD","pvalue_EarlyNAFLDvsHealthy","pvalue_EarlyWDvsHealthy","pvalue_EarlyWDvsEarlyNAFLD","pvalue_AdvancedWDvsEarlyWD","Sig_NAFLDvsHealthy","Sig_WDvsHealthy","Sig_WDvsNAFLD","Sig_EarlyNAFLDvsHealthy","Sig_EarlyWDvsHealthy","Sig_EarlyWDvsEarlyNAFLD","Sig_AdvancedWDvsEarlyWD"]
["chr1",1245722,1249722,-1,388581,"C1QTNF12","LSEC",{"v":46.8225179872657,"d":"46.8"},{"v":47.2274293760668,"d":"47.2"},{"v":46.7008245566776,"d":"46.7"},{"v":48.3985898985676,"d":"48.4"},{"v":47.2492509366544,"d":"47.2"},{"v":46.4657846795447,"d":"46.5"},{"v":5.50461552822929,"d":"5.5"},{"v":3.11098602699285,"d":"3.1"},{"v":5.76049684367953,"d":"5.8"},{"v":1.93912324271321,"d":"1.9"},{"v":4.58829718478952,"d":"4.6"},{"v":6.5224733572066,"d":"6.5"},{"v":0.404911388801132,"d":"0.4"},{"v":-0.121693430588046,"d":"-0.1"},{"v":-0.526604819389178,"d":"-0.5"},{"v":1.57607191130194,"d":"1.6"},{"v":0.4267329493887,"d":"0.4"},{"v":-1.14933896191324,"d":"-1.1"},{"v":-0.783466257109637,"d":"-0.8"},{"v":0.990968973764011,"d":"0.99"},{"v":0.998873362515811,"d":"1.00"},{"v":0.981430919505538,"d":"0.98"},{"v":0.85403062951178,"d":"0.85"},{"v":0.99025763370238,"d":"0.99"},{"v":0.941246182351732,"d":"0.94"},{"v":0.856905435577557,"d":"0.86"},false,false,false,false,false,false,false]
["chr1",1305567,1309567,1,126789,"PUSL1","HSC",{"v":11.6713413532371,"d":"11.7"},{"v":10.2484208854617,"d":"10.2"},{"v":10.3073169588066,"d":"10.3"},{"v":10.2733136575714,"d":"10.3"},{"v":12.0573397317583,"d":"12.1"},{"v":9.55730719897009,"d":"9.6"},{"v":2.27865467793685,"d":"2.3"},{"v":1.38460451008121,"d":"1.4"},{"v":2.3688265621274,"d":"2.4"},{"v":1.59751114709546,"d":"1.6"},{"v":2.14797030181914,"d":"2.1"},{"v":2.16599319410557,"d":"2.2"},{"v":-1.42292046777535,"d":"-1.4"},{"v":-1.36402439443053,"d":"-1.4"},{"v":0.0588960733448136,"d":"0.1"},{"v":-1.39802769566566,"d":"-1.4"},{"v":0.385998378521238,"d":"0.4"},{"v":1.7840260741869,"d":"1.8"},{"v":-2.50003253278825,"d":"-2.5"},{"v":0.534025969566505,"d":"0.53"},{"v":0.456054562950306,"d":"0.46"},{"v":0.99863716769629,"d":"1.00"},{"v":0.566346317416501,"d":"0.57"},{"v":0.962527833431376,"d":"0.96"},{"v":0.519302604542983,"d":"0.52"},{"v":0.132245197354533,"d":"0.13"},false,false,false,false,false,false,false]
["chr1",1321756,1325756,1,80772,"CPTP","HSC",{"v":34.7241161601236,"d":"34.7"},{"v":29.0221307604701,"d":"29.0"},{"v":33.6589105638382,"d":"33.7"},{"v":29.538533015805,"d":"29.5"},{"v":31.83437343389,"d":"31.8"},{"v":34.4408550481017,"d":"34.4"},{"v":3.74128185836703,"d":"3.7"},{"v":3.06288618328219,"d":"3.1"},{"v":7.36366932291181,"d":"7.4"},{"v":3.27575239706667,"d":"3.3"},{"v":4.2020981043997,"d":"4.2"},{"v":8.54820164972105,"d":"8.5"},{"v":-5.70198539965356,"d":"-5.7"},{"v":-1.06520559628545,"d":"-1.1"},{"v":4.63677980336811,"d":"4.6"},{"v":-5.18558314431865,"d":"-5.2"},{"v":-2.88974272623371,"d":"-2.9"},{"v":2.29584041808494,"d":"2.3"},{"v":2.60648161421179,"d":"2.6"},{"v":0.256267692963149,"d":"0.26"},{"v":0.931828022555834,"d":"0.93"},{"v":0.32732710752499,"d":"0.33"},{"v":0.125827561233035,"d":"0.13"},{"v":0.534237735962716,"d":"0.53"},{"v":0.705196838811098,"d":"0.71"},{"v":0.636722186819481,"d":"0.64"},false,false,false,false,false,false,false]
["chr1",1406313,1410313,-1,55052,"MRPL20","HEP",{"v":27.0389939925966,"d":"27.0"},{"v":22.1573630003143,"d":"22.2"},{"v":23.8572668297409,"d":"23.9"},{"v":22.8302915366524,"d":"22.8"},{"v":24.068065967869,"d":"24.1"},{"v":23.7669243419717,"d":"23.8"},{"v":5.19818383671731,"d":"5.2"},{"v":2.00169007115084,"d":"2.0"},{"v":3.73072255240715,"d":"3.7"},{"v":1.52429177690406,"d":"1.5"},{"v":4.88602856390713,"d":"4.9"},{"v":3.58997737753179,"d":"3.6"},{"v":-4.88163099228226,"d":"-4.9"},{"v":-3.18172716285569,"d":"-3.2"},{"v":1.69990382942657,"d":"1.7"},{"v":-4.20870245594414,"d":"-4.2"},{"v":-2.97092802472763,"d":"-3.0"},{"v":1.23777443121651,"d":"1.2"},{"v":-0.301141625897223,"d":"-0.3"},{"v":0.127333534766471,"d":"0.13"},{"v":0.282689350932299,"d":"0.28"},{"v":0.712557995743084,"d":"0.71"},{"v":0.33316773979399,"d":"0.33"},{"v":0.61439480690499,"d":"0.61"},{"v":0.927111639938863,"d":"0.93"},{"v":0.914836376668852,"d":"0.91"},false,false,false,false,false,false,false]
["chr1",1431861,1435861,1,64856,"VWA1","LSEC",{"v":35.2319252478207,"d":"35.2"},{"v":34.2840463470282,"d":"34.3"},{"v":32.265737513948,"d":"32.3"},{"v":35.7434605596059,"d":"35.7"},{"v":32.925577891487,"d":"32.9"},{"v":31.982948780717,"d":"32.0"},{"v":3.48566848698536,"d":"3.5"},{"v":3.52799417740725,"d":"3.5"},{"v":6.13364197961386,"d":"6.1"},{"v":1.54802829278691,"d":"1.5"},{"v":5.54346478568424,"d":"5.5"},{"v":6.77333149813174,"d":"6.8"},{"v":-0.94787890079251,"d":"-0.9"},{"v":-2.96618773387277,"d":"-3.0"},{"v":-2.01830883308026,"d":"-2.0"},{"v":0.511535311785124,"d":"0.5"},{"v":-2.30634735633375,"d":"-2.3"},{"v":-2.81788266811887,"d":"-2.8"},{"v":-0.942629110770039,"d":"-0.9"},{"v":0.947461659299579,"d":"0.95"},{"v":0.497034653931661,"d":"0.50"},{"v":0.74469446475254,"d":"0.74"},{"v":0.973670053445299,"d":"0.97"},{"v":0.6484912431493,"d":"0.65"},{"v":0.578387863843414,"d":"0.58"},{"v":0.838502107705563,"d":"0.84"},false,false,false,false,false,false,false]
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["chrX",145814832,145818832,1,84631,"SLITRK2","HEP",{"v":20.2898222226988,"d":"20.3"},{"v":22.5389009624538,"d":"22.5"},{"v":20.1565173659222,"d":"20.2"},null,null,{"v":16.407180709075,"d":"16.4"},{"v":11.756233924978,"d":"11.8"},{"v":12.9531614522503,"d":"13.0"},{"v":12.7172236590244,"d":"12.7"},null,null,{"v":13.4182054957064,"d":"13.4"},{"v":2.24907873975494,"d":"2.2"},{"v":-0.133304856776672,"d":"-0.1"},{"v":-2.38238359653161,"d":"-2.4"},{"$nulls":3},{"v":-12.4977888561572,"d":"-12.5"},{"v":0.952708281488316,"d":"0.95"},{"v":0.999765334300195,"d":"1.00"},{"v":0.935786083710091,"d":"0.94"},{"$nulls":3},{"v":0.165637543358504,"d":"0.17"},false,false,false,{"$nulls":3},false]
["chrX",147908951,147912951,1,2332,"FMR1","LSEC",{"v":28.3431953839872,"d":"28.3"},{"v":29.4892590534616,"d":"29.5"},{"v":31.5401806591214,"d":"31.5"},null,null,{"v":24.0825164682079,"d":"24.1"},{"v":17.9587092285408,"d":"18.0"},{"v":19.0799379112666,"d":"19.1"},{"v":17.4647055300569,"d":"17.5"},null,null,{"v":15.334231938059,"d":"15.3"},{"v":1.14606366947444,"d":"1.1"},{"v":3.19698527513417,"d":"3.2"},{"v":2.05092160565973,"d":"2.1"},{"$nulls":3},{"v":-24.8588806363784,"d":"-24.9"},{"v":0.993906361201839,"d":"0.99"},{"v":0.936909918033794,"d":"0.94"},{"v":0.97638473377378,"d":"0.98"},{"$nulls":3},{"v":0.0280050770933928,"d":"0.03"},false,false,false,{"$nulls":3},true]
["chrX",149878141,149882141,1,4107,"MAGEA8","HEP",{"v":89.0071496610329,"d":"89.0"},{"v":87.8614839877091,"d":"87.9"},{"v":91.0994757584869,"d":"91.1"},null,null,{"v":92.2028686126318,"d":"92.2"},{"v":5.23713984524365,"d":"5.2"},{"v":6.38342731492078,"d":"6.4"},{"v":3.72827700109395,"d":"3.7"},null,null,{"v":4.00574459148593,"d":"4.0"},{"v":-1.14566567332385,"d":"-1.1"},{"v":2.09232609745399,"d":"2.1"},{"v":3.23799177077784,"d":"3.2"},{"$nulls":3},{"v":3.67797618048306,"d":"3.7"},{"v":0.920234193075849,"d":"0.92"},{"v":0.687542488214032,"d":"0.69"},{"v":0.459130418471146,"d":"0.46"},{"$nulls":3},{"v":0.163795250600562,"d":"0.16"},false,false,false,{"$nulls":3},false]
["chrX",151692124,151696124,1,79057,"PRRG3","LSEC",{"v":41.7822876052306,"d":"41.8"},{"v":38.9716428246772,"d":"39.0"},{"v":42.9022719459427,"d":"42.9"},null,null,{"v":40.1686299788913,"d":"40.2"},{"v":10.3437657237497,"d":"10.3"},{"v":16.5225969584512,"d":"16.5"},{"v":9.36749692046623,"d":"9.4"},null,null,{"v":9.87760849102584,"d":"9.9"},{"v":-2.81064478055345,"d":"-2.8"},{"v":1.11998434071202,"d":"1.1"},{"v":3.93062912126547,"d":"3.9"},{"$nulls":3},{"v":-9.11213989017126,"d":"-9.1"},{"v":0.915755098759379,"d":"0.92"},{"v":0.980891296145687,"d":"0.98"},{"v":0.811517126734179,"d":"0.81"},{"$nulls":3},{"v":0.170595601409987,"d":"0.17"},false,false,false,{"$nulls":3},false]
["chrX",153491939,153495939,1,633,"BGN","HEP",{"v":62.5716649838903,"d":"62.6"},{"v":59.5335625074279,"d":"59.5"},{"v":56.4557975428126,"d":"56.5"},null,null,{"v":50.7117654491679,"d":"50.7"},{"v":6.69152769111582,"d":"6.7"},{"v":5.9452494112744,"d":"5.9"},{"v":13.1429750990588,"d":"13.1"},null,null,{"v":11.3063803063723,"d":"11.3"},{"v":-3.0381024764624,"d":"-3.0"},{"v":-6.11586744107775,"d":"-6.1"},{"v":-3.07776496461535,"d":"-3.1"},{"$nulls":3},{"v":-19.1467736454824,"d":"-19.1"},{"v":0.878871749584885,"d":"0.88"},{"v":0.498867557983613,"d":"0.50"},{"v":0.850746540127659,"d":"0.85"},{"$nulls":3},{"v":0.0231477173693603,"d":"0.02"},false,false,false,{"$nulls":3},true]
["chrX",153639492,153643492,1,1852,"DUSP9","HSC",{"v":46.3938573044994,"d":"46.4"},{"v":48.0453426106673,"d":"48.0"},{"v":47.3194647857754,"d":"47.3"},null,null,{"v":43.3483345019364,"d":"43.3"},{"v":14.2846048314865,"d":"14.3"},{"v":10.3217210500799,"d":"10.3"},{"v":9.30687729933649,"d":"9.3"},null,null,{"v":7.01825017707314,"d":"7.0"},{"v":1.65148530616798,"d":"1.7"},{"v":0.925607481276082,"d":"0.9"},{"v":-0.725877824891903,"d":"-0.7"},{"$nulls":3},{"v":-13.2371009461301,"d":"-13.2"},{"v":0.967445094205169,"d":"0.97"},{"v":0.985790638798142,"d":"0.99"},{"v":0.992204043641812,"d":"0.99"},{"$nulls":3},{"v":0.0281735963921776,"d":"0.03"},false,false,false,{"$nulls":3},true]
["chrX",153934223,153938223,-1,8260,"NAA10","LSEC",{"v":30.0364341617442,"d":"30.0"},{"v":29.5849984625238,"d":"29.6"},{"v":29.2768026042487,"d":"29.3"},null,null,{"v":27.7471140577713,"d":"27.7"},{"v":9.58271919103239,"d":"9.6"},{"v":6.82332281804736,"d":"6.8"},{"v":11.3732684514046,"d":"11.4"},null,null,{"v":12.5492527581977,"d":"12.5"},{"v":-0.451435699220408,"d":"-0.5"},{"v":-0.759631557495492,"d":"-0.8"},{"v":-0.308195858275084,"d":"-0.3"},{"$nulls":3},{"v":-5.09896182159133,"d":"-5.1"},{"v":0.996957041974434,"d":"1.00"},{"v":0.988211108441773,"d":"0.99"},{"v":0.998265290926926,"d":"1.00"},{"$nulls":3},{"v":0.547867435607281,"d":"0.55"},false,false,false,{"$nulls":3},false]
["chrX",153943691,153947691,-1,5973,"RENBP","LSEC",{"v":72.1633713224229,"d":"72.2"},{"v":71.6699365369615,"d":"71.7"},{"v":68.8145467784031,"d":"68.8"},null,null,{"v":67.5977980839552,"d":"67.6"},{"v":3.35885416710292,"d":"3.4"},{"v":4.5395614849847,"d":"4.5"},{"v":7.22900717800978,"d":"7.2"},null,null,{"v":8.24182300105794,"d":"8.2"},{"v":-0.493434785461417,"d":"-0.5"},{"v":-3.34882454401982,"d":"-3.3"},{"v":-2.8553897585584,"d":"-2.9"},{"$nulls":3},{"v":-4.05582898149332,"d":"-4.1"},{"v":0.989247515462511,"d":"0.99"},{"v":0.517578922860946,"d":"0.52"},{"v":0.649565006346865,"d":"0.65"},{"$nulls":3},{"v":0.448817556160999,"d":"0.45"},false,false,false,{"$nulls":3},false]
["chrX",154376197,154380197,1,2010,"EMD","LSEC",{"v":28.5992768344957,"d":"28.6"},{"v":30.8517440982364,"d":"30.9"},{"v":28.4577997722255,"d":"28.5"},null,null,{"v":19.6365615251453,"d":"19.6"},{"v":23.3258159912339,"d":"23.3"},{"v":20.3989469766803,"d":"20.4"},{"v":20.9627838322995,"d":"21.0"},null,null,{"v":18.8018042651274,"d":"18.8"},{"v":2.25246726374062,"d":"2.3"},{"v":-0.141477062270216,"d":"-0.1"},{"v":-2.39394432601084,"d":"-2.4"},{"$nulls":3},{"v":-29.4041274902673,"d":"-29.4"},{"v":0.983685467490525,"d":"0.98"},{"v":0.999910688988778,"d":"1.00"},{"v":0.977554959273791,"d":"0.98"},{"$nulls":3},{"v":0.0313375822234137,"d":"0.03"},false,false,false,{"$nulls":3},true]
["chrX",154515242,154519242,-1,60343,"FAM3A","HEP",{"v":38.1166775369306,"d":"38.1"},{"v":36.9728344094634,"d":"37.0"},{"v":35.3757948811149,"d":"35.4"},null,null,{"v":30.128972066001,"d":"30.1"},{"v":14.494164154523,"d":"14.5"},{"v":13.7931651554408,"d":"13.8"},{"v":16.8147233509433,"d":"16.8"},null,null,{"v":17.0870808445366,"d":"17.1"},{"v":-1.14384312746721,"d":"-1.1"},{"v":-2.7408826558157,"d":"-2.7"},{"v":-1.5970395283485,"d":"-1.6"},{"$nulls":3},{"v":-17.4894093837132,"d":"-17.5"},{"v":0.99190754629609,"d":"0.99"},{"v":0.938065241980587,"d":"0.94"},{"v":0.980839526362053,"d":"0.98"},{"$nulls":3},{"v":0.138883498730267,"d":"0.14"},false,false,false,{"$nulls":3},false]

{"sheet":"Table S11 Blood Samples","index":6,"n_rows":83,"n_cols":14,"rows_kept":83,"flags":["formulas_cached_only"]}
["Sequencing ID","Sex","Age","BMI","Diagnosis","Wilson Disease Presentation","Adaboost Cohort","Coverage (x)","Mappability","mCG","mCHG","mCHH","ConvEff","PCR Duplicates"]
["VMNS012B","Male",27,22.8,"Healthy Control","N/A","Training",1.7,{"v":0.713,"d":"71.3%"},{"v":0.767,"d":"76.7%"},{"v":0.017,"d":"1.7%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.275,"d":"27.5%"}]
["VMNS013B","Male",45,30.5,"Healthy Control","N/A","Training",1.4,{"v":0.725,"d":"72.5%"},{"v":0.766,"d":"76.6%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.242,"d":"24.2%"}]
["VMNS014B","Male",28,30.7,"Healthy Control","N/A","Training",1.5,{"v":0.716,"d":"71.6%"},{"v":0.774,"d":"77.4%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.23,"d":"23.0%"}]
["VMNS015B","Male",33,26.2,"Healthy Control","N/A","Training",1.7,{"v":0.722,"d":"72.2%"},{"v":0.776,"d":"77.6%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.255,"d":"25.5%"}]
["VMNS016B","Male",32,22.8,"Healthy Control","N/A","Training",1.5,{"v":0.718,"d":"71.8%"},{"v":0.772,"d":"77.2%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.227,"d":"22.7%"}]
["VMNS022B","Male",59,24.6,"Healthy Control","N/A","Training",1.3,{"v":0.681,"d":"68.1%"},{"v":0.771,"d":"77.1%"},{"v":0.024,"d":"2.4%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.227,"d":"22.7%"}]
["VMNS017B","Female",38,20.1,"Healthy Control","N/A","Training",1.8,{"v":0.721,"d":"72.1%"},{"v":0.768,"d":"76.8%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.274,"d":"27.4%"}]
["VMNS018B","Female",26,19.1,"Healthy Control","N/A","Training",1.5,{"v":0.718,"d":"71.8%"},{"v":0.764,"d":"76.4%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.246,"d":"24.6%"}]
["VMNS019B","Female",49,26.4,"Healthy Control","N/A","Training",1.5,{"v":0.715,"d":"71.5%"},{"v":0.757,"d":"75.7%"},{"v":0.017,"d":"1.7%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.237,"d":"23.7%"}]
["VMNS020B","Female",27,21.2,"Healthy Control","N/A","Training",1.4,{"v":0.724,"d":"72.4%"},{"v":0.755,"d":"75.5%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.238,"d":"23.8%"}]
["VMNS021B","Female",52,23.8,"Healthy Control","N/A","Training",1.8,{"v":0.718,"d":"71.8%"},{"v":0.768,"d":"76.8%"},{"v":0.017,"d":"1.7%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.296,"d":"29.6%"}]
["VMNS023B","Female",21,24,"Healthy Control","N/A","Training",1.3,{"v":0.73,"d":"73.0%"},{"v":0.771,"d":"77.1%"},{"v":0.022,"d":"2.2%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.25,"d":"25.0%"}]
["VMNS015A","Male",43,28.9,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.6,{"v":0.721,"d":"72.1%"},{"v":0.763,"d":"76.3%"},{"v":0.022,"d":"2.2%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.266,"d":"26.6%"}]
["VMNS026A","Male",24,39.7,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.1,{"v":0.516,"d":"51.6%"},{"v":0.783,"d":"78.3%"},{"v":0.025,"d":"2.5%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.202,"d":"20.2%"}]
["VMNS027A","Male",66,27,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.6,{"v":0.713,"d":"71.3%"},{"v":0.775,"d":"77.5%"},{"v":0.021,"d":"2.1%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.325,"d":"32.5%"}]
["VMNS028A","Male",63,29.7,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.5,{"v":0.743,"d":"74.3%"},{"v":0.756,"d":"75.6%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.262,"d":"26.2%"}]
["VMNS029A","Male",40,28.5,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.8,{"v":0.743,"d":"74.3%"},{"v":0.775,"d":"77.5%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.313,"d":"31.3%"}]
["VMNS012A","Female",52,47.3,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.3,{"v":0.715,"d":"71.5%"},{"v":0.774,"d":"77.4%"},{"v":0.021,"d":"2.1%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.218,"d":"21.8%"}]
["VMNS013A","Female",50,38.4,"Non-Alcoholic Fatty Liver Disease","N/A","Training",{"v":2,"d":"2.0"},{"v":0.727,"d":"72.7%"},{"v":0.763,"d":"76.3%"},{"v":0.019,"d":"1.9%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.323,"d":"32.3%"}]
["VMNS014A","Female",58,40.7,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.5,{"v":0.732,"d":"73.2%"},{"v":0.78,"d":"78.0%"},{"v":0.022,"d":"2.2%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.245,"d":"24.5%"}]
["VMNS028B","Female",59,30,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.7,{"v":0.739,"d":"73.9%"},{"v":0.771,"d":"77.1%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.305,"d":"30.5%"}]
["VMNS029B","Female",55,26.5,"Non-Alcoholic Fatty Liver Disease","N/A","Training",1.5,{"v":0.743,"d":"74.3%"},{"v":0.769,"d":"76.9%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.281,"d":"28.1%"}]
["VMNS021A","Male",63,21.8,"Primary Sclerosing Cholangitis","N/A","Training",1.5,{"v":0.721,"d":"72.1%"},{"v":0.776,"d":"77.6%"},{"v":0.021,"d":"2.1%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.253,"d":"25.3%"}]
["VMNS022A","Male",58,31.4,"Primary Sclerosing Cholangitis","N/A","Training",1.8,{"v":0.688,"d":"68.8%"},{"v":0.773,"d":"77.3%"},{"v":0.024,"d":"2.4%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.274,"d":"27.4%"}]
["VMNS023A","Male",61,20.8,"Primary Sclerosing Cholangitis","N/A","Training",1.3,{"v":0.724,"d":"72.4%"},{"v":0.772,"d":"77.2%"},{"v":0.022,"d":"2.2%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.254,"d":"25.4%"}]
["VMNS024A","Male",30,17.7,"Primary Sclerosing Cholangitis","N/A","Training",1.4,{"v":0.67,"d":"67.0%"},{"v":0.785,"d":"78.5%"},{"v":0.024,"d":"2.4%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.242,"d":"24.2%"}]
["VMNS025A","Male",45,37,"Primary Sclerosing Cholangitis","N/A","Training",0.8,{"v":0.448,"d":"44.8%"},{"v":0.778,"d":"77.8%"},{"v":0.026,"d":"2.6%"},{"v":0.018,"d":"1.8%"},{"v":0.982,"d":"98.2%"},{"v":0.227,"d":"22.7%"}]
["VMNS016A","Female",53,33,"Primary Sclerosing Cholangitis","N/A","Training",1.3,{"v":0.723,"d":"72.3%"},{"v":0.781,"d":"78.1%"},{"v":0.023,"d":"2.3%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.213,"d":"21.3%"}]
["VMNS017A","Female",23,21.6,"Primary Sclerosing Cholangitis","N/A","Training",1.5,{"v":0.729,"d":"72.9%"},{"v":0.763,"d":"76.3%"},{"v":0.019,"d":"1.9%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.233,"d":"23.3%"}]
["VMNS018A","Female",61,41.4,"Primary Sclerosing Cholangitis","N/A","Training",1.7,{"v":0.722,"d":"72.2%"},{"v":0.748,"d":"74.8%"},{"v":0.018,"d":"1.8%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.274,"d":"27.4%"}]
["VMNS019A","Female",45,27,"Primary Sclerosing Cholangitis","N/A","Training",1.3,{"v":0.713,"d":"71.3%"},{"v":0.771,"d":"77.1%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.2,"d":"20.0%"}]
["VMNS020A","Female",33,29.6,"Primary Sclerosing Cholangitis","N/A","Training",1.8,{"v":0.739,"d":"73.9%"},{"v":0.764,"d":"76.4%"},{"v":0.018,"d":"1.8%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.274,"d":"27.4%"}]
["VMNS014D","Male",30,24.4,"Wilson Disease","Hepatic","Training",1.7,{"v":0.724,"d":"72.4%"},{"v":0.762,"d":"76.2%"},{"v":0.018,"d":"1.8%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.253,"d":"25.3%"}]
["VMNS016C","Male",29,29,"Wilson Disease","Hepatic","Training",1.5,{"v":0.721,"d":"72.1%"},{"v":0.772,"d":"77.2%"},{"v":0.018,"d":"1.8%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.213,"d":"21.3%"}]
["VMNS019C","Male",30,27.2,"Wilson Disease","Hepatic","Training",1.8,{"v":0.713,"d":"71.3%"},{"v":0.774,"d":"77.4%"},{"v":0.02,"d":"2.0%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.235,"d":"23.5%"}]
["VMNS021C","Male",38,28.6,"Wilson Disease","Hepatic","Training",1.6,{"v":0.711,"d":"71.1%"},{"v":0.765,"d":"76.5%"},{"v":0.021,"d":"2.1%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.29,"d":"29.0%"}]
["VMNS025B","Male",44,19.7,"Wilson Disease","Hepatic","Training",0.9,{"v":0.454,"d":"45.4%"},{"v":0.767,"d":"76.7%"},{"v":0.022,"d":"2.2%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.236,"d":"23.6%"}]
["VMNS027B","Male",46,25.7,"Wilson Disease","Hepatic","Training",1.4,{"v":0.706,"d":"70.6%"},{"v":0.768,"d":"76.8%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.292,"d":"29.2%"}]
["VMNS027C","Male",43,32.6,"Wilson Disease","Hepatic","Training",1.6,{"v":0.71,"d":"71.0%"},{"v":0.772,"d":"77.2%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.303,"d":"30.3%"}]
["VMNS027D","Male",43,20.1,"Wilson Disease","Hepatic","Training",1.6,{"v":0.703,"d":"70.3%"},{"v":0.77,"d":"77.0%"},{"v":0.017,"d":"1.7%"},{"v":0.012,"d":"1.2%"},{"v":0.988,"d":"98.8%"},{"v":0.313,"d":"31.3%"}]
["VMNS029D","Male",36,22,"Wilson Disease","Hepatic","Training",1.7,{"v":0.737,"d":"73.7%"},{"v":0.769,"d":"76.9%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.323,"d":"32.3%"}]
["VMNS012D","Female",18,28.1,"Wilson Disease","Hepatic","Training",1.6,{"v":0.727,"d":"72.7%"},{"v":0.773,"d":"77.3%"},{"v":0.016,"d":"1.6%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.234,"d":"23.4%"}]
["VMNS013D","Female",60,25.7,"Wilson Disease","Hepatic","Training",1.2,{"v":0.714,"d":"71.4%"},{"v":0.758,"d":"75.8%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.237,"d":"23.7%"}]
["VMNS015C","Female",19,27.2,"Wilson Disease","Hepatic","Training",1.6,{"v":0.725,"d":"72.5%"},{"v":0.769,"d":"76.9%"},{"v":0.018,"d":"1.8%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.258,"d":"25.8%"}]
["VMNS015D","Female",30,25.2,"Wilson Disease","Hepatic","Training",1.6,{"v":0.732,"d":"73.2%"},{"v":0.765,"d":"76.5%"},{"v":0.018,"d":"1.8%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.253,"d":"25.3%"}]
["VMNS016D","Female",23,26,"Wilson Disease","Hepatic","Training",{"v":2,"d":"2.0"},{"v":0.727,"d":"72.7%"},{"v":0.765,"d":"76.5%"},{"v":0.018,"d":"1.8%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.27,"d":"27.0%"}]
["VMNS018C","Female",31,29.5,"Wilson Disease","Hepatic","Training",1.8,{"v":0.715,"d":"71.5%"},{"v":0.763,"d":"76.3%"},{"v":0.021,"d":"2.1%"},{"v":0.017,"d":"1.7%"},{"v":0.983,"d":"98.3%"},{"v":0.268,"d":"26.8%"}]
["VMNS019D","Female",24,21.4,"Wilson Disease","Hepatic","Training",1.3,{"v":0.715,"d":"71.5%"},{"v":0.764,"d":"76.4%"},{"v":0.019,"d":"1.9%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.206,"d":"20.6%"}]
["VMNS020C","Female",45,33.1,"Wilson Disease","Hepatic","Training",1.2,{"v":0.719,"d":"71.9%"},{"v":0.774,"d":"77.4%"},{"v":0.02,"d":"2.0%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.231,"d":"23.1%"}]
["VMNS023D","Female",56,20.4,"Wilson Disease","Hepatic","Training",1.7,{"v":0.706,"d":"70.6%"},{"v":0.751,"d":"75.1%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.271,"d":"27.1%"}]
["VMNS024B","Female",20,22.1,"Wilson Disease","Hepatic","Training",1.5,{"v":0.673,"d":"67.3%"},{"v":0.773,"d":"77.3%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.23,"d":"23.0%"}]
["VMNS024C","Female",32,22.9,"Wilson Disease","Hepatic","Training",1.5,{"v":0.671,"d":"67.1%"},{"v":0.776,"d":"77.6%"},{"v":0.019,"d":"1.9%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.245,"d":"24.5%"}]
["VMNS014C","Male",28,19,"Wilson Disease","Neurologic","Training",1.8,{"v":0.727,"d":"72.7%"},{"v":0.768,"d":"76.8%"},{"v":0.017,"d":"1.7%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.277,"d":"27.7%"}]
["VMNS018D","Male",42,30.7,"Wilson Disease","Neurologic","Training",1.3,{"v":0.714,"d":"71.4%"},{"v":0.759,"d":"75.9%"},{"v":0.021,"d":"2.1%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.241,"d":"24.1%"}]
["VMNS021D","Male",58,25.3,"Wilson Disease","Neurologic","Training",1.4,{"v":0.717,"d":"71.7%"},{"v":0.771,"d":"77.1%"},{"v":0.02,"d":"2.0%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.281,"d":"28.1%"}]
["VMNS022C","Male",34,28.3,"Wilson Disease","Neurologic","Training",1.4,{"v":0.679,"d":"67.9%"},{"v":0.77,"d":"77.0%"},{"v":0.021,"d":"2.1%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.244,"d":"24.4%"}]
["VMNS022D","Male",27,18.2,"Wilson Disease","Neurologic","Training",1.2,{"v":0.663,"d":"66.3%"},{"v":0.771,"d":"77.1%"},{"v":0.021,"d":"2.1%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.225,"d":"22.5%"}]
["VMNS024D","Male",24,18.9,"Wilson Disease","Neurologic","Training",1.2,{"v":0.664,"d":"66.4%"},{"v":0.776,"d":"77.6%"},{"v":0.02,"d":"2.0%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.216,"d":"21.6%"}]
["VMNS025D","Male",36,24.7,"Wilson Disease","Neurologic","Training",0.9,{"v":0.457,"d":"45.7%"},{"v":0.771,"d":"77.1%"},{"v":0.021,"d":"2.1%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.252,"d":"25.2%"}]
["VMNS026C","Male",44,25.7,"Wilson Disease","Neurologic","Training",{"v":1,"d":"1.0"},{"v":0.503,"d":"50.3%"},{"v":0.772,"d":"77.2%"},{"v":0.022,"d":"2.2%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.199,"d":"19.9%"}]
["VMNS028C","Male",52,22.7,"Wilson Disease","Neurologic","Training",1.7,{"v":0.733,"d":"73.3%"},{"v":0.757,"d":"75.7%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.288,"d":"28.8%"}]
["VMNS029C","Male",21,28.7,"Wilson Disease","Neurologic","Training",1.4,{"v":0.733,"d":"73.3%"},{"v":0.761,"d":"76.1%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.275,"d":"27.5%"}]
["VMNS012C","Female",54,20.2,"Wilson Disease","Neurologic","Training",1.7,{"v":0.737,"d":"73.7%"},{"v":0.766,"d":"76.6%"},{"v":0.017,"d":"1.7%"},{"v":0.014,"d":"1.4%"},{"v":0.986,"d":"98.6%"},{"v":0.245,"d":"24.5%"}]
["VMNS013C","Female",25,31,"Wilson Disease","Neurologic","Training",1.7,{"v":0.742,"d":"74.2%"},{"v":0.773,"d":"77.3%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.277,"d":"27.7%"}]
["VMNS017C","Female",46,23.2,"Wilson Disease","Neurologic","Training",1.6,{"v":0.726,"d":"72.6%"},{"v":0.772,"d":"77.2%"},{"v":0.02,"d":"2.0%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.241,"d":"24.1%"}]
["VMNS017D","Female",29,23.5,"Wilson Disease","Neurologic","Training",1.6,{"v":0.724,"d":"72.4%"},{"v":0.77,"d":"77.0%"},{"v":0.021,"d":"2.1%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.263,"d":"26.3%"}]
["VMNS020D","Female",49,22.7,"Wilson Disease","Neurologic","Training",1.8,{"v":0.733,"d":"73.3%"},{"v":0.762,"d":"76.2%"},{"v":0.02,"d":"2.0%"},{"v":0.016,"d":"1.6%"},{"v":0.984,"d":"98.4%"},{"v":0.279,"d":"27.9%"}]
["VMNS023C","Female",44,26.4,"Wilson Disease","Neurologic","Training",1.8,{"v":0.713,"d":"71.3%"},{"v":0.766,"d":"76.6%"},{"v":0.019,"d":"1.9%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.312,"d":"31.2%"}]
["VMNS025C","Female",46,24.5,"Wilson Disease","Neurologic","Training",{"v":1,"d":"1.0"},{"v":0.451,"d":"45.1%"},{"v":0.76,"d":"76.0%"},{"v":0.021,"d":"2.1%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.241,"d":"24.1%"}]
["VMNS026B","Female",33,25.8,"Wilson Disease","Neurologic","Training",1.1,{"v":0.512,"d":"51.2%"},{"v":0.768,"d":"76.8%"},{"v":0.021,"d":"2.1%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.23,"d":"23.0%"}]
["VMNS026D","Female",32,30.2,"Wilson Disease","Neurologic","Training",{"v":1,"d":"1.0"},{"v":0.511,"d":"51.1%"},{"v":0.768,"d":"76.8%"},{"v":0.022,"d":"2.2%"},{"v":0.015,"d":"1.5%"},{"v":0.985,"d":"98.5%"},{"v":0.21,"d":"21.0%"}]
["VMNS028D","Female",23,24.3,"Wilson Disease","Neurologic","Training",1.6,{"v":0.738,"d":"73.8%"},{"v":0.766,"d":"76.6%"},{"v":0.016,"d":"1.6%"},{"v":0.013,"d":"1.3%"},{"v":0.987,"d":"98.7%"},{"v":0.296,"d":"29.6%"}]
["VMNS005A","male",32,"N/A","Wilson Disease","Hepatic","Test",{"v":0.6978361039065423,"d":"0.7"},{"v":0.7797281331788962,"d":"78.0%"},{"v":0.7514603291821389,"d":"75.1%"},{"v":0.012180329182138953,"d":"1.2%"},{"v":0.007288449733409755,"d":"0.7%"},{"v":0.9927115502665902,"d":"99.3%"},{"v":0.07586314053223478,"d":"7.6%"}]
["VMNS006A","male",23,"N/A","Wilson Disease","Hepatic","Test",{"v":0.7062102558712513,"d":"0.7"},{"v":0.7812196627220901,"d":"78.1%"},{"v":0.7449767242647528,"d":"74.5%"},{"v":0.012851080350877094,"d":"1.3%"},{"v":0.007397744153110005,"d":"0.7%"},{"v":0.99260225584689,"d":"99.3%"},{"v":0.06412824877899205,"d":"6.4%"}]
["VMNS008A","male",43,"N/A","Wilson Disease","Hepatic","Test",{"v":0.8184540603370193,"d":"0.8"},{"v":0.7849734547680554,"d":"78.5%"},{"v":0.7578931218066924,"d":"75.8%"},{"v":0.012044548248313981,"d":"1.2%"},{"v":0.00703109224150359,"d":"0.7%"},{"v":0.9929689077584964,"d":"99.3%"},{"v":0.07704151417328521,"d":"7.7%"}]
["VMNS009A","male",22,"N/A","Wilson Disease","Hepatic","Test",{"v":0.715288967890121,"d":"0.7"},{"v":0.7903282097031856,"d":"79.0%"},{"v":0.754682307186774,"d":"75.5%"},{"v":0.011450209112805506,"d":"1.1%"},{"v":0.006690229202593876,"d":"0.7%"},{"v":0.9933097707974061,"d":"99.3%"},{"v":0.061384796089337224,"d":"6.1%"}]
["VMNS007A","female",23,"N/A","Wilson Disease","Hepatic","Test",{"v":0.7783952829051295,"d":"0.8"},{"v":0.7888183871855283,"d":"78.9%"},{"v":0.7652099057587518,"d":"76.5%"},{"v":0.012394351850082242,"d":"1.2%"},{"v":0.007112325180573484,"d":"0.7%"},{"v":0.9928876748194265,"d":"99.3%"},{"v":0.07454426189658164,"d":"7.5%"}]
["VMNS005C","male",24,"N/A","Wilson Disease","Neurologic","Test",{"v":0.8809090780659262,"d":"0.9"},{"v":0.7842899632326106,"d":"78.4%"},{"v":0.7542010535541946,"d":"75.4%"},{"v":0.012318364253401572,"d":"1.2%"},{"v":0.007232742971307125,"d":"0.7%"},{"v":0.9927672570286928,"d":"99.3%"},{"v":0.07723767245853742,"d":"7.7%"}]
["VMNS006C","male",35,"N/A","Wilson Disease","Neurologic","Test",{"v":0.7840785222098224,"d":"0.8"},{"v":0.7783287054014745,"d":"77.8%"},{"v":0.7403913536911626,"d":"74.0%"},{"v":0.012323791952336042,"d":"1.2%"},{"v":0.007257893185868547,"d":"0.7%"},{"v":0.9927421068141314,"d":"99.3%"},{"v":0.07049651077463265,"d":"7.0%"}]
["VMNS008C","male",23,"N/A","Wilson Disease","Neurologic","Test",{"v":0.8100313064365051,"d":"0.8"},{"v":0.7804125734940591,"d":"78.0%"},{"v":0.7528535912685429,"d":"75.3%"},{"v":0.011643252686412926,"d":"1.2%"},{"v":0.007331358308390793,"d":"0.7%"},{"v":0.9926686416916092,"d":"99.3%"},{"v":0.06637971488274595,"d":"6.6%"}]
["VMNS009C","male",31,"N/A","Wilson Disease","Neurologic","Test",{"v":0.9402531993953315,"d":"0.9"},{"v":0.7918711544843133,"d":"79.2%"},{"v":0.7533370673945446,"d":"75.3%"},{"v":0.011687592693493263,"d":"1.2%"},{"v":0.006739428091458026,"d":"0.7%"},{"v":0.993260571908542,"d":"99.3%"},{"v":0.0764100606288166,"d":"7.6%"}]
["VMNS007C","female",29,"N/A","Wilson Disease","Neurologic","Test",{"v":0.7361816528225594,"d":"0.7"},{"v":0.7834946785175586,"d":"78.3%"},{"v":0.7546139875338189,"d":"75.5%"},{"v":0.011797092086964143,"d":"1.2%"},{"v":0.007158961016911465,"d":"0.7%"},{"v":0.9928410389830885,"d":"99.3%"},{"v":0.06882743530067593,"d":"6.9%"}]

{"sheet":"Table S12 WD Specific Blood","index":7,"n_rows":263,"n_cols":40,"rows_kept":263,"flags":["formulas_cached_only"]}
["DMR_Set","chr","start","end","CpGs","meanReads","width","areaStat","HC_mean","WD_mean","meanDiff","direction","confIntL","confIntR","tstat","pValue","FWER","Rel_FWER","Genome_Significant","Sex_estimate","Sex_pvalue","Sex_pAdj","Age_estimate","Age_pvalue","Age_pAdj","OnsetAge_estimate","OnsetAge_pvalue","OnsetAge_pAdj","Height_estimate","Height_pvalue","Height_pAdj","Weight_estimate","Weight_pvalue","Weight_pAdj","BMI_estimate","BMI_pvalue","BMI_pAdj","gene_name","distanceToTSS","position"]
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{"sheet":"Table S13 Human-Mouse Overlap","index":8,"n_rows":28,"n_cols":8,"rows_kept":28,"flags":["formulas_cached_only"]}
["HumanDMR","MouseDMR","oddsRatio","intersects","pvalue","qvalue","Sig","Genes"]
["Liver All"," All",{"v":2.65420493919341,"d":"2.65"},37,{"v":1.86037216462423e-06,"d":"1.9E-06"},{"v":5.02300484448542e-05,"d":"5.0E-05"},true,"AFAP1, ALKBH5, AMN, B4GALNT4, BCL2L10, C15orf39, C17orf107, CACNA1H, CAMK2B, CLCNKB, CNTN2, ELFN1, FAM129B, FAM83F, GRID2IP, HLCS, KDELR2, LONRF2, MAD1L1, MAGI1, MLXIPL, MYO15A, PKP3, PRKCE, PXDN, RPL12, SALL1, SH3PXD2A, SH3RF3, SIM2, SMAD6, TMEM184A, TPSG1, TRIM11, WNT11, YKT6, ZNF750"]
["Liver Hyper"," All",{"v":2.07078977487488,"d":"2.07"},18,{"v":0.00552574267319471,"d":"0.006"},{"v":0.0135631865614779,"d":"0.014"},true,"ALKBH5, AMN, B4GALNT4, C17orf107, CACNA1H, ELFN1, GRID2IP, KDELR2, MAD1L1, MAGI1, MLXIPL, MYO15A, PKP3, PXDN, SH3RF3, TMEM184A, TPSG1, ZNF750"]
["Liver Hypo"," All",{"v":3.101082006076,"d":"3.10"},24,{"v":6.47028648735029e-06,"d":"6.5E-06"},{"v":8.7348867579229e-05,"d":"8.7E-05"},true,"AFAP1, B4GALNT4, BCL2L10, C15orf39, C17orf107, CACNA1H, CAMK2B, CLCNKB, CNTN2, FAM129B, FAM83F, HLCS, LONRF2, MAD1L1, PRKCE, RPL12, SALL1, SH3PXD2A, SIM2, SMAD6, TPSG1, TRIM11, WNT11, YKT6"]
["Liver Early All"," All",{"v":1.83655045645897,"d":"1.84"},4,{"v":0.182078543594273,"d":"0.182"},{"v":0.245806033852269,"d":"0.246"},false,"CACNA1H, PXDN, SMAD6, TPSG1"]
["Liver Early Hyper"," All",{"v":2.92083676975575,"d":"2.92"},4,{"v":0.0534310280603509,"d":"0.053"},{"v":0.0901648598518421,"d":"0.090"},false,"CACNA1H, PXDN, SMAD6, TPSG1"]
["Liver Early Hypo"," All",{"v":1.20532530785553,"d":"1.21"},1,{"v":0.566821898785339,"d":"0.567"},{"v":0.637674636133506,"d":"0.638"},false,"PXDN"]
["Blood All"," All",{"v":3.24350794486488,"d":"3.24"},9,{"v":0.00282576544528402,"d":"0.003"},{"v":0.00762956670226686,"d":"0.008"},true,"AMN, B3GNTL1, CCDC70, CNTN2, MAD1L1, NFASC, QRFP, TAF8, ZNF750"]
["Blood Hyper"," All",{"v":2.38985045591569,"d":"2.39"},5,{"v":0.0652969861475092,"d":"0.065"},{"v":0.103706977998985,"d":"0.104"},false,"B3GNTL1, CNTN2, NFASC, TAF8, ZNF750"]
["Blood Hypo"," All",{"v":7.84531680204296,"d":"7.85"},6,{"v":0.000184841850046254,"d":"1.8E-04"},{"v":0.000939618298568994,"d":"0.001"},true,"AMN, B3GNTL1, CCDC70, MAD1L1, QRFP, ZNF750"]
["Liver All"," Hyper",{"v":2.57705176172954,"d":"2.58"},15,{"v":0.00250603342133093,"d":"0.003"},{"v":0.0075181002639928,"d":"0.008"},true,"ALKBH5, BCL2L10, C17orf107, CLCNKB, CNTN2, GRID2IP, KDELR2, MLXIPL, MYO15A, PRKCE, SALL1, SH3PXD2A, SMAD6, TMEM184A, ZNF750"]
["Liver Hyper"," Hyper",{"v":2.24376962838006,"d":"2.24"},8,{"v":0.0369940584813116,"d":"0.037"},{"v":0.0768338137688779,"d":"0.077"},false,"ALKBH5, C17orf107, GRID2IP, KDELR2, MLXIPL, MYO15A, TMEM184A, ZNF750"]
["Liver Hypo"," Hyper",{"v":2.39712664718644,"d":"2.40"},8,{"v":0.0269500943803529,"d":"0.027"},{"v":0.060637712355794,"d":"0.061"},false,"BCL2L10, C17orf107, CLCNKB, CNTN2, PRKCE, SALL1, SH3PXD2A, SMAD6"]
["Liver Early All"," Hyper",{"v":1.0948596410801,"d":"1.09"},1,{"v":0.602536109988901,"d":"0.603"},{"v":0.650738998788013,"d":"0.651"},false,"SMAD6"]
["Liver Early Hyper"," Hyper",{"v":1.73245347439248,"d":"1.73"},1,{"v":0.443228670529456,"d":"0.443"},{"v":0.543962459286151,"d":"0.544"},false,"SMAD6"]
["Liver Early Hypo"," Hyper",{"v":0,"d":"0.00"},0,{"v":1,"d":"1.000"},{"v":1,"d":"1.000"},false]
["Blood All"," Hyper",{"v":6.4564929427258,"d":"6.46"},7,{"v":0.000202090635116244,"d":"2.0E-04"},{"v":0.000939618298568994,"d":"0.001"},true,"B3GNTL1, CCDC70, CNTN2, NFASC, QRFP, TAF8, ZNF750"]
["Blood Hyper"," Hyper",{"v":6.09885914803765,"d":"6.10"},5,{"v":0.00194752905391229,"d":"0.002"},{"v":0.00657291055695397,"d":"0.007"},true,"B3GNTL1, CNTN2, NFASC, TAF8, ZNF750"]
["Blood Hypo"," Hyper",{"v":12.8203994886272,"d":"12.82"},4,{"v":0.000380175019821922,"d":"3.8E-04"},{"v":0.00146638936217027,"d":"0.001"},true,"B3GNTL1, CCDC70, QRFP, ZNF750"]
["Liver All"," Hypo",{"v":2.65050029407673,"d":"2.65"},22,{"v":0.000208804066348665,"d":"2.1E-04"},{"v":0.000939618298568994,"d":"0.001"},true,"AFAP1, AMN, B4GALNT4, C15orf39, CACNA1H, CAMK2B, ELFN1, FAM129B, FAM83F, HLCS, LONRF2, MAD1L1, MAGI1, PKP3, PXDN, RPL12, SH3RF3, SIM2, TPSG1, TRIM11, WNT11, YKT6"]
["Liver Hyper"," Hypo",{"v":1.91603734471658,"d":"1.92"},10,{"v":0.0490139429879785,"d":"0.049"},{"v":0.0901648598518421,"d":"0.090"},false,"AMN, B4GALNT4, CACNA1H, ELFN1, MAD1L1, MAGI1, PKP3, PXDN, SH3RF3, TPSG1"]
["Liver Hypo"," Hypo",{"v":3.55074312751139,"d":"3.55"},16,{"v":5.21896708565015e-05,"d":"5.2E-05"},{"v":0.000469707037708513,"d":"4.7E-04"},true,"AFAP1, B4GALNT4, C15orf39, CACNA1H, CAMK2B, FAM129B, FAM83F, HLCS, LONRF2, MAD1L1, RPL12, SIM2, TPSG1, TRIM11, WNT11, YKT6"]
["Liver Early All"," Hypo",{"v":2.33605436695617,"d":"2.34"},3,{"v":0.144900374531379,"d":"0.145"},{"v":0.205911058544592,"d":"0.206"},false,"CACNA1H, PXDN, TPSG1"]
["Liver Early Hyper"," Hypo",{"v":3.70918878957684,"d":"3.71"},3,{"v":0.0517183776634765,"d":"0.052"},{"v":0.0901648598518421,"d":"0.090"},false,"CACNA1H, PXDN, TPSG1"]
["Liver Early Hypo"," Hypo",{"v":2.04516535334675,"d":"2.05"},1,{"v":0.39098140652041,"d":"0.391"},{"v":0.502690379811956,"d":"0.503"},false,"PXDN"]
["Blood All"," Hypo",{"v":1.15391342129761,"d":"1.15"},2,{"v":0.521436060205323,"d":"0.521"},{"v":0.612120592414944,"d":"0.612"},false,"AMN, MAD1L1"]
["Blood Hyper"," Hypo",{"v":0,"d":"0.00"},0,{"v":1,"d":"1.000"},{"v":1,"d":"1.000"},false]
["Blood Hypo"," Hypo",{"v":4.20194514767683,"d":"4.20"},2,{"v":0.086408204027808,"d":"0.086"},{"v":0.129612306041712,"d":"0.130"},false,"AMN, MAD1L1"]

{"sheet":"Table S14 WD Hep vs Neuro Blood","index":9,"n_rows":2861,"n_cols":40,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1},"flags":["formulas_cached_only"]}
["DMR_Set","chr","start","end","CpGs","meanReads","width","areaStat","HC_mean","WD_mean","meanDiff","direction","confIntL","confIntR","tstat","pValue","FWER","Rel_FWER","Genome_Significant","Sex_estimate","Sex_pvalue","Sex_pAdj","Age_estimate","Age_pvalue","Age_pAdj","OnsetAge_estimate","OnsetAge_pvalue","OnsetAge_pAdj","Height_estimate","Height_pvalue","Height_pAdj","Weight_estimate","Weight_pvalue","Weight_pAdj","BMI_estimate","BMI_pvalue","BMI_pAdj","gene_name","distanceToTSS","position"]
["WD_Hep_vs_Neuro_Blood","chr1",955083,955429,10,{"v":35.075,"d":"35"},346,{"v":39.8873518730865,"d":"39.89"},{"v":0.736104294414394,"d":"0.74"},{"v":0.818755419139872,"d":"0.82"},{"v":0.0826511247254778,"d":"0.08"},"hyper",{"v":0.0298984550112124,"d":"0.03"},{"v":0.135401544988788,"d":"0.14"},{"v":3.18855091251592,"d":"3.19"},{"v":0.00314161336682264,"d":"3.14E-03"},1000,{"v":1,"d":"1.000"},false,{"v":-0.000625062656641528,"d":"-0.001"},{"v":0.983246247745623,"d":"0.983"},{"v":1,"d":"1.000"},{"v":0.00175499073645206,"d":"0.002"},{"v":0.168449679130962,"d":"0.168"},{"v":1,"d":"1.000"},{"v":0.000762447721769755,"d":"0.001"},{"v":0.543512642812534,"d":"0.544"},{"v":1,"d":"1.000"},{"v":0.00314617719900934,"d":"0.003"},{"v":0.0324216013874929,"d":"0.032"},{"v":1,"d":"1.000"},{"v":0.00111813131355198,"d":"0.001"},{"v":0.270266852307367,"d":"0.270"},{"v":1,"d":"1.000"},{"v":-0.000734742857582891,"d":"-0.001"},{"v":0.848331395554388,"d":"0.848"},{"v":1,"d":"1.000"},"SAMD11, KLHL17","29343, -5157","downstream, upstream"]
["WD_Hep_vs_Neuro_Blood","chr1",967515,967995,10,{"v":34.75,"d":"35"},480,{"v":-34.7098729867775,"d":"-34.71"},{"v":0.687142880732687,"d":"0.69"},{"v":0.620886869690389,"d":"0.62"},{"v":-0.0662560110422982,"d":"-0.07"},"hypo",{"v":-0.122964073230797,"d":"-0.12"},{"v":-0.00954592676920321,"d":"-0.01"},{"v":-2.365193680952,"d":"-2.37"},{"v":0.0232301934843994,"d":"2.32E-02"},1000,{"v":1,"d":"1.000"},false,{"v":0.0101285714285714,"d":"0.010"},{"v":0.736455635537403,"d":"0.736"},{"v":1,"d":"1.000"},{"v":0.000989179018063921,"d":"0.001"},{"v":0.454255511425832,"d":"0.454"},{"v":1,"d":"1.000"},{"v":0.000785664758969846,"d":"0.001"},{"v":0.542593472696969,"d":"0.543"},{"v":1,"d":"1.000"},{"v":-0.000675613166094115,"d":"-0.001"},{"v":0.664263470466653,"d":"0.664"},{"v":1,"d":"1.000"},{"v":-0.00182902342824216,"d":"-0.002"},{"v":0.0756137971956191,"d":"0.076"},{"v":1,"d":"1.000"},{"v":-0.00665618942458949,"d":"-0.007"},{"v":0.0857798952412357,"d":"0.086"},{"v":1,"d":"1.000"},"PLEKHN1, PERM1","1019, 14122","gene_body, downstream"]
["WD_Hep_vs_Neuro_Blood","chr1",1005512,1005636,5,{"v":15.075,"d":"15"},124,{"v":-15.9977607888569,"d":"-16.00"},{"v":0.417361030466796,"d":"0.42"},{"v":0.343963874761404,"d":"0.34"},{"v":-0.0733971557053918,"d":"-0.07"},"hypo",{"v":-0.138300370028359,"d":"-0.14"},{"v":-0.008489629971641,"d":"-0.01"},{"v":-2.29120796143279,"d":"-2.29"},{"v":0.0277428359397048,"d":"2.77E-02"},1000,{"v":1,"d":"1.000"},false,{"v":-0.00480375939849625,"d":"-0.005"},{"v":0.890407922843458,"d":"0.890"},{"v":1,"d":"1.000"},{"v":-0.00049956963100201,"d":"-0.000"},{"v":0.740783090533758,"d":"0.741"},{"v":1,"d":"1.000"},{"v":-0.000808344339276546,"d":"-0.001"},{"v":0.582481091836942,"d":"0.582"},{"v":1,"d":"1.000"},{"v":-0.00219448083939175,"d":"-0.002"},{"v":0.211630396077329,"d":"0.212"},{"v":1,"d":"1.000"},{"v":-0.000196056550041608,"d":"-0.000"},{"v":0.869911052471713,"d":"0.870"},{"v":1,"d":"1.000"},{"v":0.00331943816393644,"d":"0.003"},{"v":0.459086087283303,"d":"0.459"},{"v":1,"d":"1.000"},"HES4, ISG15","-5340, -7830","upstream, upstream"]
["WD_Hep_vs_Neuro_Blood","chr1",1013784,1013908,6,{"v":20.5,"d":"21"},124,{"v":-16.1309948315825,"d":"-16.13"},{"v":0.36010805883838,"d":"0.36"},{"v":0.297728817991111,"d":"0.30"},{"v":-0.0623792408472687,"d":"-0.06"},"hypo",{"v":-0.117089214452616,"d":"-0.12"},{"v":-0.00768078554738415,"d":"-0.01"},{"v":-2.30912654528647,"d":"-2.31"},{"v":0.0265057492583799,"d":"2.65E-02"},1000,{"v":1,"d":"1.000"},false,{"v":-0.0347736842105263,"d":"-0.035"},{"v":0.222811959058435,"d":"0.223"},{"v":1,"d":"1.000"},{"v":-0.0018036455920951,"d":"-0.002"},{"v":0.151794455310303,"d":"0.152"},{"v":1,"d":"1.000"},{"v":-0.00146996661530559,"d":"-0.001"},{"v":0.232822095030889,"d":"0.233"},{"v":1,"d":"1.000"},{"v":-0.000950892120050071,"d":"-0.001"},{"v":0.524627425369805,"d":"0.525"},{"v":1,"d":"1.000"},{"v":-0.00171270074075981,"d":"-0.002"},{"v":0.0839299467819512,"d":"0.084"},{"v":1,"d":"1.000"},{"v":-0.00596476075293084,"d":"-0.006"},{"v":0.110276479157812,"d":"0.110"},{"v":1,"d":"1.000"},"ISG15",318,"gene_body"]
["WD_Hep_vs_Neuro_Blood","chr1",1060674,1060939,16,{"v":56.825,"d":"57"},265,{"v":41.0708099253005,"d":"41.07"},{"v":0.655786589633478,"d":"0.66"},{"v":0.708951961802433,"d":"0.71"},{"v":0.0531653721689541,"d":"0.05"},"hyper",{"v":0.0155162940885395,"d":"0.02"},{"v":0.0907937059114604,"d":"0.09"},{"v":2.86453108122324,"d":"2.86"},{"v":0.00693869224711163,"d":"6.94E-03"},1000,{"v":1,"d":"1.000"},false,{"v":0.0338824561403509,"d":"0.034"},{"v":0.102624814643526,"d":"0.103"},{"v":1,"d":"1.000"},{"v":0.00114322024085225,"d":"0.001"},{"v":0.201514765132622,"d":"0.202"},{"v":1,"d":"1.000"},{"v":0.00126707938953702,"d":"0.001"},{"v":0.145179652638502,"d":"0.145"},{"v":1,"d":"1.000"},{"v":0.00017071050038614,"d":"0.000"},{"v":0.87238001202713,"d":"0.872"},{"v":1,"d":"1.000"},{"v":0.00158743896095243,"d":"0.002"},{"v":0.021879681390694,"d":"0.022"},{"v":1,"d":"1.000"},{"v":0.00700894382366644,"d":"0.007"},{"v":0.00629428547700062,"d":"0.006"},{"v":1,"d":"1.000"},"AGRN, RNF223","40552, 13368","downstream, downstream"]
["WD_Hep_vs_Neuro_Blood","chr1",1215024,1215425,7,{"v":20.525,"d":"21"},401,{"v":19.0072173559271,"d":"19.01"},{"v":0.646330557561731,"d":"0.65"},{"v":0.711932145075496,"d":"0.71"},{"v":0.0656015875137653,"d":"0.07"},"hyper",{"v":0.0202135162559831,"d":"0.02"},{"v":0.111016483744017,"d":"0.11"},{"v":2.92979886465947,"d":"2.93"},{"v":0.00582134916050155,"d":"5.82E-03"},1000,{"v":1,"d":"1.000"},false,{"v":0.00357067669172928,"d":"0.004"},{"v":0.8863807854301,"d":"0.886"},{"v":1,"d":"1.000"},{"v":0.000157667515825225,"d":"0.000"},{"v":0.885651135194594,"d":"0.886"},{"v":1,"d":"1.000"},{"v":0.00082956746643187,"d":"0.001"},{"v":0.435886943183639,"d":"0.436"},{"v":1,"d":"1.000"},{"v":0.000671725120502783,"d":"0.001"},{"v":0.601355703745255,"d":"0.601"},{"v":1,"d":"1.000"},{"v":0.00060183209898605,"d":"0.001"},{"v":0.487075141418615,"d":"0.487"},{"v":1,"d":"1.000"},{"v":0.000996185634181109,"d":"0.001"},{"v":0.760148273948109,"d":"0.760"},{"v":1,"d":"1.000"},"TNFRSF4",-856,"upstream"]
["WD_Hep_vs_Neuro_Blood","chr1",1237078,1237528,14,{"v":41.725,"d":"42"},450,{"v":-44.592013717674,"d":"-44.59"},{"v":0.686555375983686,"d":"0.69"},{"v":0.627167599558747,"d":"0.63"},{"v":-0.059387776424939,"d":"-0.06"},"hypo",{"v":-0.108385561412484,"d":"-0.11"},{"v":-0.0104044385875162,"d":"-0.01"},{"v":-2.45634614978233,"d":"-2.46"},{"v":0.0188408897865331,"d":"1.88E-02"},1000,{"v":1,"d":"1.000"},false,{"v":-0.00787142857142864,"d":"-0.008"},{"v":0.763559680628187,"d":"0.764"},{"v":1,"d":"1.000"},{"v":7.1180716381038e-05,"d":"0.000"},{"v":0.950688180134716,"d":"0.951"},{"v":1,"d":"1.000"},{"v":0.000811730501137278,"d":"0.001"},{"v":0.467893413490336,"d":"0.468"},{"v":1,"d":"1.000"},{"v":-0.00307525631807409,"d":"-0.003"},{"v":0.0182979492759171,"d":"0.018"},{"v":1,"d":"1.000"},{"v":-0.000992512291100507,"d":"-0.001"},{"v":0.272606445552397,"d":"0.273"},{"v":1,"d":"1.000"},{"v":0.000936392155822584,"d":"0.001"},{"v":0.784593071594819,"d":"0.785"},{"v":1,"d":"1.000"},"SDF4, FAM132A","-5011, 9194","upstream, downstream"]
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["WD_Hep_vs_Neuro_Blood","chr9",137174964,137175363,24,{"v":77.975,"d":"78"},399,{"v":72.0770616984519,"d":"72.08"},{"v":0.590380707279263,"d":"0.59"},{"v":0.670828975483895,"d":"0.67"},{"v":0.0804482682046325,"d":"0.08"},"hyper",{"v":0.0119916138194592,"d":"0.01"},{"v":0.148918386180541,"d":"0.15"},{"v":2.38292717818379,"d":"2.38"},{"v":0.0225491955502121,"d":"2.25E-02"},990,{"v":0.99,"d":"0.990"},false,{"v":0.028315037593985,"d":"0.028"},{"v":0.439862156814177,"d":"0.440"},{"v":1,"d":"1.000"},{"v":0.00144259881117802,"d":"0.001"},{"v":0.364839685174249,"d":"0.365"},{"v":1,"d":"1.000"},{"v":0.00111790483527772,"d":"0.001"},{"v":0.472248016455741,"d":"0.472"},{"v":1,"d":"1.000"},{"v":0.00214386967058134,"d":"0.002"},{"v":0.250036554911438,"d":"0.250"},{"v":1,"d":"1.000"},{"v":0.000891225899561661,"d":"0.001"},{"v":0.480773532349662,"d":"0.481"},{"v":1,"d":"1.000"},{"v":-5.40197366479322e-06,"d":"-0.000"},{"v":0.999095734660006,"d":"0.999"},{"v":1,"d":"1.000"},"LRRC26, TMEM210","-4925, -2918","upstream, upstream"]
["WD_Hep_vs_Neuro_Blood","chr9",137244115,137244716,13,{"v":41.325,"d":"41"},601,{"v":-39.8017284642054,"d":"-39.80"},{"v":0.782412160398745,"d":"0.78"},{"v":0.720364706580969,"d":"0.72"},{"v":-0.0620474538177751,"d":"-0.06"},"hypo",{"v":-0.102997757047454,"d":"-0.10"},{"v":-0.021082242952546,"d":"-0.02"},{"v":-3.06715645955835,"d":"-3.07"},{"v":0.00398540760967018,"d":"3.99E-03"},1000,{"v":1,"d":"1.000"},false,{"v":-0.0147157894736842,"d":"-0.015"},{"v":0.516615905302672,"d":"0.517"},{"v":1,"d":"1.000"},{"v":-5.5708661417318e-05,"d":"-0.000"},{"v":0.955531292712203,"d":"0.956"},{"v":1,"d":"1.000"},{"v":-0.000378450363196121,"d":"-0.000"},{"v":0.697318637431391,"d":"0.697"},{"v":1,"d":"1.000"},{"v":-0.000949151820191208,"d":"-0.001"},{"v":0.416600670367399,"d":"0.417"},{"v":1,"d":"1.000"},{"v":0.000206127339814379,"d":"0.000"},{"v":0.794460592468294,"d":"0.794"},{"v":1,"d":"1.000"},{"v":0.00313272375922948,"d":"0.003"},{"v":0.288707549947453,"d":"0.289"},{"v":1,"d":"1.000"},"TUBB4B, STPG3","2857, -6544","downstream, upstream"]
["WD_Hep_vs_Neuro_Blood","chr9",137305266,137305494,15,{"v":59.375,"d":"59"},228,{"v":37.5710595743268,"d":"37.57"},{"v":0.481285814376357,"d":"0.48"},{"v":0.541835735517058,"d":"0.54"},{"v":0.0605499211407008,"d":"0.06"},"hyper",{"v":0.000229585648458665,"d":"0.00"},{"v":0.120870414351541,"d":"0.12"},{"v":2.03601166807441,"d":"2.04"},{"v":0.049179495867657,"d":"4.92E-02"},1000,{"v":1,"d":"1.000"},false,{"v":-0.0453293233082707,"d":"-0.045"},{"v":0.148927785310742,"d":"0.149"},{"v":1,"d":"1.000"},{"v":0.00080866141732283,"d":"0.001"},{"v":0.558400994295404,"d":"0.558"},{"v":1,"d":"1.000"},{"v":0.00100756842028028,"d":"0.001"},{"v":0.453850250960126,"d":"0.454"},{"v":1,"d":"1.000"},{"v":0.000135005725546595,"d":"0.000"},{"v":0.933862013115024,"d":"0.934"},{"v":1,"d":"1.000"},{"v":-6.35483023402487e-05,"d":"-0.000"},{"v":0.953817801136523,"d":"0.954"},{"v":1,"d":"1.000"},{"v":-0.00011175116439548,"d":"-0.000"},{"v":0.978382214128947,"d":"0.978"},{"v":1,"d":"1.000"},"NRARP",-3015,"upstream"]
["WD_Hep_vs_Neuro_Blood","chr9",137592702,137593210,8,{"v":24.225,"d":"24"},508,{"v":24.4741949587322,"d":"24.47"},{"v":0.738185013653098,"d":"0.74"},{"v":0.801022633227159,"d":"0.80"},{"v":0.0628376195740609,"d":"0.06"},"hyper",{"v":0.00375606291080852,"d":"0.00"},{"v":0.121923937089191,"d":"0.12"},{"v":2.16949608714641,"d":"2.17"},{"v":0.0378601046002912,"d":"3.79E-02"},1000,{"v":1,"d":"1.000"},false,{"v":-0.00768922305764419,"d":"-0.008"},{"v":0.80465931602866,"d":"0.805"},{"v":1,"d":"1.000"},{"v":-0.000670951057588389,"d":"-0.001"},{"v":0.620650427068656,"d":"0.621"},{"v":1,"d":"1.000"},{"v":-0.000746313009024873,"d":"-0.001"},{"v":0.572100725255879,"d":"0.572"},{"v":1,"d":"1.000"},{"v":0.00107792069452212,"d":"0.001"},{"v":0.49786152369242,"d":"0.498"},{"v":1,"d":"1.000"},{"v":-0.000525563141766573,"d":"-0.001"},{"v":0.624636648451374,"d":"0.625"},{"v":1,"d":"1.000"},{"v":-0.00462246719649674,"d":"-0.005"},{"v":0.248751030533121,"d":"0.249"},{"v":1,"d":"1.000"},"ZMYND19",-2217,"upstream"]

{"sheet":"Table S15 Adaboost WD HvN Blood","index":10,"n_rows":45,"n_cols":10,"rows_kept":45,"flags":["formulas_cached_only"]}
["chr","start","end","meanDiff (H - N)","Direction (H - N)","Adaboost Importance","gene_name","description","distanceToTSS","position"]
["chr1",4363599,4363762,-0.07,"Hypomethylated",0.02,"LINC01346, LOC284661","long intergenic non-protein coding RNA 1346, LOC284661","422988, -48288","downstream, upstream"]
["chr1",53692771,53693233,0.06,"Hypermethylated",0.02,"DMRTB1, GLIS1","DMRT like family B with proline rich C-terminal 1, GLIS family zinc finger 1","233373, 40971","downstream, gene_body"]
["chr1",115426181,115426565,0.07,"Hypermethylated",0.02,"NGF, VANGL1","nerve growth factor, VANGL planar cell polarity protein 1","-87945, -215387","upstream, upstream"]
["chr1",180208140,180208612,-0.06,"Hypomethylated",0.02,"LHX4, FLJ23867","LIM homeobox 4, FLJ23867","-21685, 10132","upstream, downstream"]
["chr1",223726321,223726503,0.07,"Hypermethylated",0.02,"CAPN2, TP53BP2","calpain 2, tumor protein p53 binding protein 2","24729, 119469","gene_body, downstream"]
["chr2",1939845,1940120,-0.06,"Hypomethylated",0.02,"PXDN, MYT1L-AS1","peroxidasin, MYT1L antisense RNA 1","-195298, -379111","upstream, upstream"]
["chr2",78106109,78106862,-0.07,"Hypomethylated",0.02,"LOC101927967, LOC101927948","LOC101927967, LOC101927948","183869, 17380","gene_body, gene_body"]
["chr2",107187250,107188134,-0.07,"Hypomethylated",0.04,"ST6GAL2, GACAT1","ST6 beta-galactoside alpha-2,6-sialyltransferase 2, gastric cancer associated transcript 1","-300143, -565977","upstream, upstream"]
["chr2",130337215,130337895,-0.1,"Hypomethylated",0.02,"TUBA3E, IMP4","tubulin alpha 3e, IMP4, U3 small nucleolar ribonucleoprotein","-138754, -4329","upstream, upstream"]
["chr2",223870572,223870910,-0.05,"Hypomethylated",0.02,"AP1S3, WDFY1","adaptor related protein complex 1 subunit sigma 3, WD repeat and FYVE domain containing 1","-32970, 74477","upstream, downstream"]
["chr2",231227938,231228470,-0.08,"Hypomethylated",0.02,"ARMC9, MIR4777","armadillo repeat containing 9, microRNA 4777","29393, -134237","gene_body, upstream"]
["chr3",46988341,46988903,-0.08,"Hypomethylated",0.02,"CCDC12, NRADDP","coiled-coil domain containing 12, neurotrophin receptor associated death domain, pseudogene","-6331, -22638","upstream, upstream"]
["chr3",52498513,52498939,-0.05,"Hypomethylated",0.02,"STAB1, SMIM4","stabilin 1, small integral membrane protein 4","3174, -37665","gene_body, upstream"]
["chr3",149496499,149496625,0.08,"Hypermethylated",0.02,"TM4SF4, WWTR1-AS1","transmembrane 4 L six family member 4, WWTR1 antisense RNA 1","21919, -161584","gene_body, upstream"]
["chr5",139712098,139712414,-0.1,"Hypomethylated",0.02,"CXXC5, LOC101929696","CXXC finger protein 5, LOC101929696","64800, 33809","downstream, downstream"]
["chr5",169143443,169143795,0.06,"Hypermethylated",0.04,"MIR585, LOC728095","microRNA 585, LOC728095","119899, 130217","downstream, downstream"]
["chr5",180089733,180089812,0.09,"Hypermethylated",0.02,"RNF130, RASGEF1C","ring finger protein 130, RasGEF domain family member 1C","-17615, 119318","upstream, downstream"]
["chr6",36848656,36849327,-0.08,"Hypomethylated",0.02,"CPNE5, C6orf89","copine 5, chromosome 6 open reading frame 89","-9212, -22542","upstream, upstream"]
["chr7",47560525,47561178,0.06,"Hypermethylated",0.02,"TNS3, LOC730338","tensin 3, LOC730338","20966, -863403","gene_body, upstream"]
["chr7",75989737,75990474,-0.06,"Hypomethylated",0.02,"SNORA14A, TMEM120A","small nucleolar RNA, H/ACA box 14A, transmembrane protein 120A","45955, 4200","downstream, gene_body"]
["chr7",140232268,140232705,0.07,"Hypermethylated",0.04,"KDM7A, SLC37A3","lysine demethylase 7A, solute carrier family 37 member 3","-55327, 165845","upstream, downstream"]
["chr7",155787793,155788211,0.08,"Hypermethylated",0.02,"SHH, LOC100506302","sonic hedgehog, LOC100506302","24062, -143387","downstream, upstream"]
["chr8",6942645,6943508,-0.06,"Hypomethylated",0.02,"DEFA4, DEFA8P","defensin alpha 4, defensin alpha 8, pseudogene","-4307, 8091","upstream, downstream"]
["chr8",42692270,42692714,0.07,"Hypermethylated",0.02,"SLC20A2, CHRNB3","solute carrier family 20 member 2, cholinergic receptor nicotinic beta 3 subunit","-150057, -4704","upstream, upstream"]
["chr8",142200097,142200575,-0.07,"Hypomethylated",0.02,"LINC00051, TSNARE1","long intergenic non-protein coding RNA 51, t-SNARE domain containing 1","1742, 202674","gene_body, downstream"]
["chr9",127972174,127972380,0.08,"Hypermethylated",0.02,"DPM2, FAM102A","dolichyl-phosphate mannosyltransferase subunit 2, regulatory, family with sequence similarity 102 member A","-33690, 8153","upstream, gene_body"]
["chr12",7439574,7440027,-0.1,"Hypomethylated",0.02,"ACSM4, CD163L1","acyl-CoA synthetase medium chain family member 4, CD163 molecule like 1","135243, 4158","downstream, gene_body"]
["chr12",49962056,49962336,-0.08,"Hypomethylated",0.02,"AQP5, LOC101927318","aquaporin 5, LOC101927318","561, 588","gene_body, gene_body"]
["chr13",110644542,110645291,-0.08,"Hypomethylated",0.02,"NAXD, CARS2","NAD(P)HX dehydratase, cysteinyl-tRNA synthetase 2, mitochondrial","29083, 60889","downstream, gene_body"]
["chr14",99679708,99679939,-0.11,"Hypomethylated",0.06,"CYP46A1","cytochrome P450 family 46 subfamily A member 1",-4478,"upstream"]
["chr15",52791556,52792018,0.06,"Hypermethylated",0.02,"ONECUT1","one cut homeobox 1",-1544,"upstream"]
["chr15",67080086,67080802,-0.1,"Hypomethylated",0.02,"IQCH, LOC102723493","IQ motif containing H, LOC102723493","-173997, -15904","upstream, upstream"]
["chr16",84951720,84952965,0.07,"Hypermethylated",0.02,"CRISPLD2, ZDHHC7","cysteine rich secretory protein LCCL domain containing 2, zinc finger DHHC-type containing 7","131740, 58570","downstream, downstream"]
["chr16",85602827,85603393,0.06,"Hypermethylated",0.02,"MIR5093, GSE1","microRNA 5093, Gse1 coiled-coil protein","-296502, -8029","upstream, upstream"]
["chr16",88902604,88903164,-0.05,"Hypomethylated",0.04,"LOC100129697, LOC101927793","LOC100129697, LOC101927793","-36874, 19090","upstream, downstream"]
["chr17",81794617,81794993,0.1,"Hypermethylated",0.02,"SLC25A10, GCGR","solute carrier family 25 member 10, glucagon receptor","82382, -9138","downstream, upstream"]
["chr18",77256127,77256421,-0.07,"Hypomethylated",0.02,"GALR1, LINC01029","galanin receptor 1, long intergenic non-protein coding RNA 1029","6076, 737306","gene_body, downstream"]
["chr21",38853366,38853644,0.08,"Hypermethylated",0.02,"LOC101928398","LOC101928398",-3894,"upstream"]
["chr21",42155324,42156295,-0.08,"Hypomethylated",0.02,"UMODL1-AS1, ABCG1","UMODL1 antisense RNA 1, ATP binding cassette subfamily G member 1","-46790, -43393","upstream, upstream"]
["chr22",31106888,31107279,0.11,"Hypermethylated",0.02,"SELM","SELM",286,"gene_body"]
["chr22",38824330,38824512,-0.07,"Hypomethylated",0.02,"DNAL4, NPTXR","dynein axonemal light chain 4, neuronal pentraxin receptor","-30174, 19500","upstream, gene_body"]
["chr22",42698466,42698842,-0.05,"Hypomethylated",0.02,"CYB5R3, A4GALT","cytochrome b5 reductase 3, alpha 1,4-galactosyltransferase (P blood group)","-49067, 22459","upstream, gene_body"]
["chr22",45285257,45285371,0.11,"Hypermethylated",0.02,"UPK3A","uroplakin 3A",271,"gene_body"]
["chr22",45868201,45868407,0.07,"Hypermethylated",0.02,"MIR4762, WNT7B","microRNA 4762, Wnt family member 7B","107678, 108721","downstream, downstream"]