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["© 2000-2024 QIAGEN. All rights reserved."]
["Ingenuity Canonical Pathways"," -log(p-value)","Ratio","z-score","Molecules"]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation","9,07E00","5,21E-02",{"$error":"#NUM!"},"CCL2,CD14,COL12A1,COL5A3,ICAM1,IL1R2,IL6,MMP13,MMP2,SERPINE1"]
["Inhibition of Matrix Metalloproteases","8,55E00","1,58E-01","0,447","MMP13,MMP2,SDC2,TFPI2,THBS2,TIMP3"]
["Role of Osteoclasts in Rheumatoid Arthritis Signaling Pathway","6,99E00","3,14E-02","-1,000","BIRC3,COL12A1,COL5A3,CTNNB1,IL1R2,MMP13,MMP2,NFKBIA,RND3,SFRP4"]
["Tumor Microenvironment Pathway","6,82E00","4,44E-02","-1,134","CCL2,CD44,CSPG4,ICAM1,IL6,MMP13,MMP2,TNC"]
["LXR/RXR Activation","6,56E00","5,34E-02","1,633","APOD,CCL2,CD14,IL1R2,IL6,PLTP,S100A8"]
["Atherosclerosis Signaling","6,43E00","5,11E-02","-1,633","APOD,CCL2,COL5A3,ICAM1,IL6,MMP13,S100A8"]
["Semaphorin Neuronal Repulsive Signaling Pathway","6,2E00","4,73E-02","-0,378","ACAN,CD44,CSPG4,FYN,PDE4B,SEMA3F,SEMA6D"]
["Hepatic Fibrosis Signaling Pathway","5,91E00","2,4E-02","0,333","CCL2,CTNNB1,FTH1,ICAM1,IL1R2,MMP13,NFKBIA,RND3,SERPINE1,SOD2"]
["Osteoarthritis Pathway","5,87E00","3,33E-02","-1,890","ACAN,CTNNB1,EPAS1,IL1R2,MMP13,PTH1R,S100A8,TIMP3"]
["Extracellular matrix organization","5,82E00","5,61E-02","1,633","ACAN,ASPN,COL5A3,SERPINE1,TNC,TNN"]
["Neutrophil degranulation","5,39E00","2,1E-02","-3,162","CD14,CD44,CDA,CHI3L1,FTH1,GPR84,LAMP1,PDXK,S100A12,S100A8"]
["Irritable Bowel Syndrome Signaling Pathway","5,26E00","2,76E-02","-2,121","BIRC3,CCL2,IL1R2,IL6,MMP13,MMP2,RND3,TNIP1"]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis","4,95E00","3,06E-02",{"$error":"#NUM!"},"BIRC3,CTNNB1,IL1R2,IL6,MMP13,NFKBIA,SFRP4"]
["Oncostatin M Signaling","4,9E00","9,3E-02",{"$error":"#NUM!"},"CHI3L1,EPAS1,MMP13,TIMP3"]
["Interleukin-10 signaling","4,82E00","8,89E-02","-2,000","CCL2,ICAM1,IL1R2,IL6"]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","4,79E00","2,37E-02","-1,134","CCL2,CTNNB1,ICAM1,IL1R2,IL6,MMP13,NFKBIA,SFRP4"]
["HOTAIR Regulatory Pathway","4,72E00","3,61E-02","-1,633","CD44,CTNNB1,ICAM1,MMP13,MMP2,NFKBIA"]
["Leukocyte Extravasation Signaling","4,34E00","3,09E-02","-1,633","CD44,CTNNB1,ICAM1,MMP13,MMP2,TIMP3"]
["Collagen degradation","4,21E00","6,25E-02","-1,000","COL12A1,COL5A3,MMP13,MMP2"]
["Granulocyte Adhesion and Diapedesis","4,19E00","2,91E-02",{"$error":"#NUM!"},"CCL2,ICAM1,IL1R2,MMP13,MMP2,SDC2"]
["Glycosaminoglycan metabolism","4,17E00","3,91E-02","1,342","ACAN,CD44,CSPG4,OGN,SDC2"]
["Activin Inhibin Signaling Pathway","4,12E00","2,83E-02","-0,816","CTNNB1,IL1R2,IL6,MMP2,NFKBIA,SERPINE1"]
["HIF1α Signaling","4,12E00","2,83E-02","-0,816","ADM,IL6,MMP13,MMP2,SAT1,SERPINE1"]
["Glioma Invasiveness Signaling","4,04E00","5,63E-02","0,000","CD44,MMP2,RND3,TIMP3"]
["Syndecan interactions","4,01E00","1,11E-01",{"$error":"#NUM!"},"COL5A3,SDC2,TNC"]
["Pulmonary Fibrosis Idiopathic Signaling Pathway","3,97E00","2,15E-02","-1,633","COL12A1,COL5A3,CTNNB1,IL6,MMP13,MMP2,SERPINE1"]
["Role of Chondrocytes in Rheumatoid Arthritis Signaling Pathway","3,93E00","3,47E-02","-2,000","CCL2,IL1R2,IL6,MMP13,MMP2"]
["Neuroinflammation Signaling Pathway","3,93E00","2,11E-02","-2,236","BACE2,BIRC3,CCL2,CTNNB1,ICAM1,IL6,SOD2"]
["Molecular Mechanisms of Cancer","3,88E00","1,27E-02","-1,897","ARHGEF5,BIRC3,CTNNB1,FYN,GPR84,IL1R2,MMP13,MMP2,NFKBIA,PTH1R,RND3"]
["VDR/RXR Activation","3,88E00","5,13E-02",{"$error":"#NUM!"},"CD14,CYP27B1,GADD45A,THBD"]
["IL-17A Signaling in Fibroblasts","3,83E00",0.05,{"$error":"#NUM!"},"CCL2,IL6,NFKBIA,ZC3H12A"]
["Degradation of the extracellular matrix","3,81E00","4,94E-02","-1,000","ACAN,CD44,MMP13,MMP2"]
["TNFR2 Signaling","3,75E00","9,09E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA,TNFAIP3"]
["Integrin cell surface interactions","3,73E00","4,71E-02","-1,000","CD44,COL5A3,ICAM1,TNC"]
["Cyclophilin Signaling Pathway","3,73E00","2,4E-02","-1,633","CCL2,CD44,CTNNB1,IL6,MMP2,NFKBIA"]
["HMGB1 Signaling","3,71E00","3,12E-02",{"$error":"#NUM!"},"CCL2,ICAM1,IL6,RND3,SERPINE1"]
["Regulation of CDH19 Expression and Function","3,65E00","2,86E-01",{"$error":"#NUM!"},"CTNNB1,ZC3H12A"]
["Salvage Pathways of Pyrimidine Deoxyribonucleotides","3,65E00","2,86E-01",{"$error":"#NUM!"},"CDA,UPP1"]
["Acute Phase Response Signaling","3,36E00","2,62E-02","-1,342","CFB,IL6,NFKBIA,SERPINE1,SOD2"]
["Macrophage Alternative Activation Signaling Pathway","3,35E00","2,6E-02","-1,342","EPAS1,IL1R2,IL6,NFKBIA,ZC3H12A"]
["NOD1/2 Signaling Pathway","3,33E00","2,58E-02",{"$error":"#NUM!"},"BIRC3,CCL2,IL6,NFKBIA,TNFAIP3"]
["Role of IL-17F in Allergic Inflammatory Airway Diseases","3,32E00","6,52E-02",{"$error":"#NUM!"},"CCL2,IL6,MMP13"]
["IL-33 Signaling Pathway","3,31E00","2,55E-02","-1,000","CCL2,ICAM1,IL6,MMP2,NFKBIA"]
["Interleukin-4 and Interleukin-13 signaling","3,29E00","3,6E-02","-1,000","CCL2,ICAM1,IL6,MMP2"]
["Airway Pathology in Chronic Obstructive Pulmonary Disease","3,25E00","3,51E-02",{"$error":"#NUM!"},"APOD,CCL2,IL6,MMP2"]
["Pulmonary Healing Signaling Pathway","3,23E00","2,45E-02","-2,236","CTNNB1,FYN,MMP13,MMP2,NFKBIA"]
["RAR Activation","3,22E00","1,61E-02","1,134","IL6,MMP13,MMP2,PDE4B,RND3,STRA6,TNIP1"]
["Sheddase Signaling Pathway","3,22E00","2,44E-02","-0,447","CD44,IL6,MMP13,MMP2,TIMP3"]
["FAT10 Cancer Signaling Pathway","3,19E00","5,88E-02",{"$error":"#NUM!"},"CTNNB1,IL6,NFKBIA"]
["TNFR1 Signaling","3,16E00","5,77E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA,TNFAIP3"]
["Vitamin D (calciferol) metabolism","3,16E00","1,67E-01",{"$error":"#NUM!"},"CYP27B1,LGMN"]
["Regulation of Insulin-like Growth Factor (IGF) transport and uptake by IGFBPs","3,11E00","3,23E-02","0,000","IL6,MMP2,SDC2,TNC"]
["Glucocorticoid Receptor Signaling","3,06E00","1,33E-02",{"$error":"#NUM!"},"CCL2,ICAM1,IL1R2,IL6,MMP13,MMP2,NFKBIA,SERPINE1"]
["IL-6 Signaling","3,05E00","3,1E-02",{"$error":"#NUM!"},"CD14,IL1R2,IL6,NFKBIA"]
["CSDE1 Signaling Pathway","3,05E00","5,26E-02",{"$error":"#NUM!"},"CCL2,CTNNB1,TNC"]
["Signaling by PDGF","3,02E00","5,17E-02",{"$error":"#NUM!"},"COL5A3,THBS2,THBS4"]
["Role of IL-17A in Arthritis","3,02E00","5,17E-02",{"$error":"#NUM!"},"CCL2,MMP13,NFKBIA"]
["Assembly of collagen fibrils and other multimeric structures","2,96E00","4,92E-02",{"$error":"#NUM!"},"COL12A1,COL5A3,MMP13"]
["CGAS-STING Signaling Pathway","2,94E00","2,9E-02",{"$error":"#NUM!"},"CCL2,ICAM1,IL6,NFKBIA"]
["S100 Family Signaling Pathway","2,93E00","1,14E-02","-1,667","CTNNB1,GPR84,IL6,MMP13,MMP2,PTH1R,S100A12,S100A2,S100A8"]
["Role of Osteoblasts in Rheumatoid Arthritis Signaling Pathway","2,91E00","2,08E-02","-1,342","CTNNB1,IL6,MMP13,MMP2,SFRP4"]
["Iron homeostasis signaling pathway","2,86E00","2,76E-02",{"$error":"#NUM!"},"EPAS1,FTH1,IL6,SLC39A14"]
["CD40 Signaling","2,84E00","4,48E-02",{"$error":"#NUM!"},"ICAM1,NFKBIA,TNFAIP3"]
["Wound Healing Signaling Pathway","2,81E00","1,98E-02","-0,447","COL12A1,COL5A3,IL1R2,IL6,NFKBIA"]
["Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17F","2,8E00","1,11E-01",{"$error":"#NUM!"},"CCL2,IL6"]
["Hematoma Resolution Signaling Pathway","2,77E00","1,93E-02","0,447","FTH1,IL6,MMP13,MMP2,SOD2"]
["Pathogen Induced Cytokine Storm Signaling Pathway","2,76E00","1,56E-02","-1,342","CCL2,COL12A1,COL5A3,FTH1,IL1R2,IL6"]
["IL-10 Signaling","2,75E00","2,58E-02","2,000","ICAM1,IL1R2,IL6,NFKBIA"]
["Colorectal Cancer Metastasis Signaling","2,69E00","1,85E-02","-1,342","CTNNB1,IL6,MMP13,MMP2,RND3"]
["Toll-like Receptor Signaling","2,67E00","3,9E-02",{"$error":"#NUM!"},"CD14,NFKBIA,TNFAIP3"]
["TREM1 Signaling","2,64E00","3,8E-02",{"$error":"#NUM!"},"CCL2,ICAM1,IL6"]
["Role of MAPK Signaling in Inhibiting the Pathogenesis of Influenza","2,62E00","3,75E-02",{"$error":"#NUM!"},"CCL2,IL6,NFKBIA"]
["DDX58/IFIH1-mediated induction of interferon-alpha/beta","2,61E00","3,7E-02",{"$error":"#NUM!"},"NFKBIA,S100A12,TNFAIP3"]
["Regulation of TLR by endogenous ligand","2,58E00","8,7E-02",{"$error":"#NUM!"},"CD14,S100A8"]
["Nucleotide salvage","2,58E00","8,7E-02",{"$error":"#NUM!"},"CDA,UPP1"]
["Apelin Cardiac Fibroblast Signaling Pathway","2,58E00","8,7E-02",{"$error":"#NUM!"},"IL6,SERPINE1"]
["BEX2 Signaling Pathway","2,58E00","3,61E-02",{"$error":"#NUM!"},"CTNNB1,MMP2,NFKBIA"]
["Interleukin-6 family signaling","2,55E00","8,33E-02",{"$error":"#NUM!"},"CRLF1,IL6"]
["Erythropoietin Signaling Pathway","2,51E00","2,21E-02",{"$error":"#NUM!"},"BIRC3,CTNNB1,IL6,NFKBIA"]
["Senescence Pathway","2,49E00","1,67E-02","0,447","GADD45A,IL6,PDK3,SERPINE1,SOD2"]
["Hepatitis B Chronic Liver Pathogenesis Signaling Pathway","2,45E00","2,13E-02","-2,000","CCL2,CTNNB1,IL6,MMP2"]
["ATF4 activates genes in response to endoplasmic reticulum stress","2,44E00","7,41E-02",{"$error":"#NUM!"},"CCL2,HERPUD1"]
["IL-17 Signaling","2,44E00","2,12E-02",{"$error":"#NUM!"},"CCL2,IL6,MMP13,MMP2"]
["EPH-Ephrin signaling","2,44E00","3,23E-02",{"$error":"#NUM!"},"FYN,MMP2,SDC2"]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages","2,42E00","2,08E-02","0,000","APOD,NFKBIA,RND3,S100A8"]
["FXR/RXR Activation","2,39E00","2,05E-02","1,000","GCLM,ICAM1,IL6,PLTP"]
["ID1 Signaling Pathway","2,32E00","1,96E-02","-2,000","CTNNB1,FYN,IL6,MMP2"]
["Serotonin Receptor Signaling","2,32E00","1,27E-02","-0,816","CD44,FYN,IL6,MMP2,NFKBIA,RND3"]
["IL-8 Signaling","2,29E00","1,92E-02",{"$error":"#NUM!"},"ICAM1,MMP2,NFKBIA,RND3"]
["Coronavirus Pathogenesis Pathway","2,27E00","1,9E-02",{"$error":"#NUM!"},"CCL2,IL6,NFKBIA,SERPINE1"]
["Activation of Matrix Metalloproteinases","2,27E00","6,06E-02",{"$error":"#NUM!"},"MMP13,MMP2"]
["Inhibition of Angiogenesis by TSP1","2,27E00","6,06E-02",{"$error":"#NUM!"},"FYN,SDC2"]
["Post-translational protein phosphorylation","2,27E00","2,8E-02",{"$error":"#NUM!"},"IL6,SDC2,TNC"]
["Cell surface interactions at the vascular wall","2,24E00","1,86E-02","-1,000","CD44,FYN,SDC2,THBD"]
["Coagulation System","2,22E00","5,71E-02",{"$error":"#NUM!"},"SERPINE1,THBD"]
["Hepatic Cholestasis","2,18E00","1,79E-02","-2,000","CD14,IL1R2,IL6,NFKBIA"]
["Detoxification of Reactive Oxygen Species","2,17E00","5,41E-02",{"$error":"#NUM!"},"GPX3,SOD2"]
["Agranulocyte Adhesion and Diapedesis","2,17E00","1,77E-02",{"$error":"#NUM!"},"CCL2,ICAM1,MMP13,MMP2"]
["MyD88-independent TLR4 cascade","2,15E00","5,26E-02",{"$error":"#NUM!"},"BIRC3,CD14"]
["TWEAK Signaling","2,15E00","5,26E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA"]
["MIF-mediated Glucocorticoid Regulation","2,15E00","5,26E-02",{"$error":"#NUM!"},"CD14,NFKBIA"]
["Axonal Guidance Signaling","2,13E00","1,16E-02",{"$error":"#NUM!"},"FYN,MMP13,MMP2,SDC2,SEMA3F,SEMA6D"]
["Transcriptional Regulation by VENTX","2,11E00",0.05,{"$error":"#NUM!"},"CTNNB1,IL6"]
["Sertoli Cell-Germ Cell Junction Signaling Pathway (Enhanced)","2,1E00","1,69E-02","0,000","CTNNB1,ICAM1,IL1R2,MMP2"]
["IL-13 Signaling Pathway","2,08E00","2,4E-02",{"$error":"#NUM!"},"CHI3L1,CTNNB1,FYN"]
["MyD88:MAL(TIRAP) cascade initiated on plasma membrane","2,07E00","4,76E-02",{"$error":"#NUM!"},"CD14,S100A8"]
["Intrinsic Prothrombin Activation Pathway","2,05E00","4,65E-02",{"$error":"#NUM!"},"COL5A3,THBD"]
["ROBO SLIT Signaling Pathway","2,04E00","2,33E-02",{"$error":"#NUM!"},"CTNNB1,FYN,MMP2"]
["GP6 Signaling Pathway","2,04E00","2,33E-02",{"$error":"#NUM!"},"COL12A1,COL5A3,FYN"]
["TAK1-dependent IKK and NF-kappa-B activation","2,03E00","4,55E-02",{"$error":"#NUM!"},"NFKBIA,S100A12"]
["Collagen chain trimerization","2,03E00","4,55E-02",{"$error":"#NUM!"},"COL12A1,COL5A3"]
["Serine Biosynthesis",2,"3,33E-01",{"$error":"#NUM!"},"PSAT1"]
["1,25-dihydroxyvitamin D3 Biosynthesis",2,"3,33E-01",{"$error":"#NUM!"},"CYP27B1"]
["Glutathione Biosynthesis",2,"3,33E-01",{"$error":"#NUM!"},"GCLM"]
["MIF Regulation of Innate Immunity","1,99E00","4,35E-02",{"$error":"#NUM!"},"CD14,NFKBIA"]
["Ferroptosis Signaling Pathway","1,98E00","2,21E-02",{"$error":"#NUM!"},"FTH1,SAT1,SLC39A14"]
["Reelin Signaling in Neurons","1,95E00","2,14E-02",{"$error":"#NUM!"},"ARHGEF5,FYN,PDK3"]
["iNOS Signaling","1,94E00","4,08E-02",{"$error":"#NUM!"},"CD14,NFKBIA"]
["Ephrin A Signaling","1,94E00","2,13E-02",{"$error":"#NUM!"},"ARHGEF5,EPAS1,FYN"]
["Deubiquitination","1,93E00","1,51E-02","-2,000","BIRC3,NFKBIA,TNFAIP3,TNIP1"]
["Neutrophil Extracellular Trap Signaling Pathway","1,92E00","1,21E-02","-1,342","CD14,COL12A1,COL5A3,FYN,MMP2"]
["NR1H2 and NR1H3-mediated signaling","1,91E00","3,92E-02",{"$error":"#NUM!"},"APOD,PLTP"]
["G alpha (s) signalling events","1,91E00","2,07E-02",{"$error":"#NUM!"},"ADM,GPR84,PTH1R"]
["NRF2-mediated Oxidative Stress Response","1,9E00","1,48E-02",{"$error":"#NUM!"},"FTH1,GCLM,HERPUD1,SOD2"]
["Spermine and Spermidine Degradation I","1,88E00","2,5E-01",{"$error":"#NUM!"},"SAT1"]
["WNT/SHH Axonal Guidance Signaling Pathway","1,85E00","1,97E-02",{"$error":"#NUM!"},"CTNNB1,FYN,SEMA3F"]
["NLR signaling pathways","1,83E00","3,57E-02",{"$error":"#NUM!"},"BIRC3,TNFAIP3"]
["TNF signaling","1,81E00","3,51E-02",{"$error":"#NUM!"},"BIRC3,TNFAIP3"]
["Ovarian Cancer Signaling","1,8E00","1,89E-02",{"$error":"#NUM!"},"CD44,CTNNB1,MMP2"]
["Semaphorin Signaling in Neurons","1,79E00","3,39E-02",{"$error":"#NUM!"},"FYN,RND3"]
["Polyamine Regulation in Colon Cancer","1,79E00","3,39E-02",{"$error":"#NUM!"},"CTNNB1,SAT1"]
["HEY1 Signaling Pathway","1,78E00","1,86E-02",{"$error":"#NUM!"},"IL6,MMP13,MMP2"]
["Reelin signalling pathway","1,78E00",0.2,{"$error":"#NUM!"},"FYN"]
["Superpathway of Serine and Glycine Biosynthesis I","1,78E00",0.2,{"$error":"#NUM!"},"PSAT1"]
["NCAM signaling for neurite out-growth","1,73E00","3,17E-02",{"$error":"#NUM!"},"COL5A3,FYN"]
["Cytosolic sensors of pathogen-associated DNA","1,72E00","3,12E-02",{"$error":"#NUM!"},"CTNNB1,NFKBIA"]
["Semaphorin interactions","1,72E00","3,12E-02",{"$error":"#NUM!"},"FYN,SEMA6D"]
["NFE2L2 regulating inflammation associated genes","1,71E00","1,67E-01",{"$error":"#NUM!"},"CCL2"]
["Ribonucleotide Reductase Signaling Pathway","1,7E00","1,72E-02",{"$error":"#NUM!"},"CTNNB1,IL6,MMP2"]
["WNT/β-catenin Signaling","1,7E00","1,72E-02",{"$error":"#NUM!"},"CD44,CTNNB1,SFRP4"]
["Activation of IRF by Cytosolic Pattern Recognition Receptors","1,69E00","3,03E-02",{"$error":"#NUM!"},"IL6,NFKBIA"]
["Induction of Apoptosis by HIV1","1,69E00","3,03E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA"]
["Collagen biosynthesis and modifying enzymes","1,68E00","2,99E-02",{"$error":"#NUM!"},"COL12A1,COL5A3"]
["Synaptogenesis Signaling Pathway","1,67E00","1,26E-02","0,000","CTNNB1,FYN,THBS2,THBS4"]
["IL-17A Signaling in Airway Cells","1,67E00","2,94E-02",{"$error":"#NUM!"},"IL6,NFKBIA"]
["Macrophage Classical Activation Signaling Pathway","1,61E00","1,6E-02",{"$error":"#NUM!"},"CD14,IL6,NFKBIA"]
["trans-Golgi Network Vesicle Budding","1,59E00","2,67E-02",{"$error":"#NUM!"},"FTH1,PICALM"]
["Superoxide Radicals Degradation","1,58E00","1,25E-01",{"$error":"#NUM!"},"SOD2"]
["Angiopoietin Signaling","1,57E00","2,6E-02",{"$error":"#NUM!"},"NFKBIA,TNIP1"]
["PPARα/RXRα Activation","1,56E00","1,52E-02",{"$error":"#NUM!"},"IL1R2,IL6,NFKBIA"]
["Serine biosynthesis","1,53E00","1,11E-01",{"$error":"#NUM!"},"PSAT1"]
["PI3K/AKT Signaling","1,53E00","1,49E-02",{"$error":"#NUM!"},"CTNNB1,IL1R2,NFKBIA"]
["G-Protein Coupled Receptor Signaling","1,51E00","8,4E-03","-0,816","CTNNB1,FYN,GPR84,NFKBIA,PDE4B,PTH1R"]
["PEDF Signaling","1,5E00","2,38E-02",{"$error":"#NUM!"},"NFKBIA,SOD2"]
["Clathrin-mediated Endocytosis Signaling","1,49E00","1,44E-02",{"$error":"#NUM!"},"APOD,PICALM,S100A8"]
["Role of Tissue Factor in Cancer","1,49E00","1,44E-02",{"$error":"#NUM!"},"FYN,MMP13,MMP2"]
["LPS-stimulated MAPK Signaling","1,49E00","2,35E-02",{"$error":"#NUM!"},"CD14,NFKBIA"]
["Cardiac Hypertrophy Signaling (Enhanced)","1,48E00","9,29E-03","-2,236","CTNNB1,IL1R2,IL6,PDE4B,RCAN1"]
["Cachexia Signaling Pathway","1,47E00","1,09E-02",{"$error":"#NUM!"},"CCL2,IL1R2,IL6,PTH1R"]
["NAP1L1 Transcription Regulation Signaling Pathway","1,45E00","2,25E-02",{"$error":"#NUM!"},"CTNNB1,NFKBIA"]
["Pexophagy","1,45E00","9,09E-02",{"$error":"#NUM!"},"EPAS1"]
["RHOGDI Signaling","1,43E00","1,36E-02",{"$error":"#NUM!"},"ARHGEF5,CD44,RND3"]
["Cell junction organization","1,43E00","2,17E-02",{"$error":"#NUM!"},"CTNNB1,SDK1"]
["Role of Hypercytokinemia/hyperchemokinemia in the Pathogenesis of Influenza","1,43E00","2,17E-02",{"$error":"#NUM!"},"CCL2,IL6"]
["RANK Signaling in Osteoclasts","1,42E00","2,15E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA"]
["Glycation Signaling Pathway","1,41E00","1,33E-02",{"$error":"#NUM!"},"CCL2,ICAM1,IL6"]
["Reversible hydration of carbon dioxide","1,41E00","8,33E-02",{"$error":"#NUM!"},"CA12"]
["γ-glutamyl Cycle","1,41E00","8,33E-02",{"$error":"#NUM!"},"GCLM"]
["Class B/2 (Secretin family receptors)","1,39E00","2,08E-02",{"$error":"#NUM!"},"ADM,PTH1R"]
["HER-2 Signaling in Breast Cancer","1,39E00","1,31E-02",{"$error":"#NUM!"},"FYN,MMP2,NFKBIA"]
["Interferon gamma signaling","1,38E00","2,04E-02",{"$error":"#NUM!"},"CD44,ICAM1"]
["Death Receptor Signaling","1,38E00","2,04E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA"]
["Trafficking and processing of endosomal TLR","1,37E00","7,69E-02",{"$error":"#NUM!"},"LGMN"]
["SUMOylation of immune response proteins","1,37E00","7,69E-02",{"$error":"#NUM!"},"NFKBIA"]
["Dissolution of Fibrin Clot","1,37E00","7,69E-02",{"$error":"#NUM!"},"SERPINE1"]
["Advanced glycosylation endproduct receptor signaling","1,37E00","7,69E-02",{"$error":"#NUM!"},"S100A12"]
["p53 Signaling","1,37E00","2,02E-02",{"$error":"#NUM!"},"CTNNB1,GADD45A"]
["Salvage Pathways of Pyrimidine Ribonucleotides","1,37E00","2,02E-02",{"$error":"#NUM!"},"CDA,UPP1"]
["ATM Signaling","1,36E00",0.02,{"$error":"#NUM!"},"GADD45A,NFKBIA"]
["Sumoylation Pathway","1,35E00","1,98E-02",{"$error":"#NUM!"},"NFKBIA,RND3"]
["Formation of axial mesoderm","1,34E00","7,14E-02",{"$error":"#NUM!"},"CTNNB1"]
["Role of IL-17A in Psoriasis","1,34E00","7,14E-02",{"$error":"#NUM!"},"S100A8"]
["Apoptosis Signaling","1,32E00","1,9E-02",{"$error":"#NUM!"},"BIRC3,NFKBIA"]
["Sertoli Cell-Sertoli Cell Junction Signaling","1,31E00","1,21E-02",{"$error":"#NUM!"},"CTNNB1,ICAM1,IL1R2"]
["Signaling by VEGF","1,3E00","1,85E-02",{"$error":"#NUM!"},"CTNNB1,FYN"]
["PPAR Signaling","1,3E00","1,85E-02",{"$error":"#NUM!"},"IL1R2,NFKBIA"]
["Xenobiotic Metabolism AHR Signaling Pathway","1,29E00","1,83E-02",{"$error":"#NUM!"},"CYP1B1,IL6"]
["Caspase activation via Death Receptors in the presence of ligand","1,29E00","6,25E-02",{"$error":"#NUM!"},"CD14"]
["Platelet Adhesion to exposed collagen","1,29E00","6,25E-02",{"$error":"#NUM!"},"FYN"]
["Extrinsic Prothrombin Activation Pathway","1,29E00","6,25E-02",{"$error":"#NUM!"},"THBD"]
["Phase I - Functionalization of compounds","1,27E00","1,77E-02",{"$error":"#NUM!"},"CYP1B1,CYP27B1"]
["Transcriptional regulation of pluripotent stem cells","1,26E00","5,88E-02",{"$error":"#NUM!"},"EPAS1"]
["FOXO-mediated transcription of cell cycle genes","1,26E00","5,88E-02",{"$error":"#NUM!"},"GADD45A"]
["Germ layer formation at gastrulation","1,26E00","5,88E-02",{"$error":"#NUM!"},"CTNNB1"]
["Specification of the neural plate border","1,26E00","5,88E-02",{"$error":"#NUM!"},"CTNNB1"]
["Prostate Cancer Signaling","1,25E00","1,72E-02",{"$error":"#NUM!"},"CTNNB1,NFKBIA"]
["Formation of definitive endoderm","1,24E00","5,56E-02",{"$error":"#NUM!"},"CTNNB1"]
["Formation of the nephric duct","1,24E00","5,56E-02",{"$error":"#NUM!"},"CTNNB1"]
["Bladder Cancer Signaling","1,23E00","1,68E-02",{"$error":"#NUM!"},"MMP13,MMP2"]
["Chaperone Mediated Autophagy Signaling Pathway","1,21E00","7,82E-03","1,342","MMP13,MMP2,NFKBIA,RCAN1,RND3"]
["IL-15 Production","1,21E00","1,64E-02",{"$error":"#NUM!"},"FYN,IL6"]
["RHOA Signaling","1,2E00","1,63E-02",{"$error":"#NUM!"},"RND3,SEMA3F"]
["Interleukin-12 family signaling","1,19E00",0.05,{"$error":"#NUM!"},"CRLF1"]
["Th1 Pathway","1,19E00","1,6E-02",{"$error":"#NUM!"},"ICAM1,IL6"]
["Opioid Signaling Pathway","1,17E00","1,06E-02",{"$error":"#NUM!"},"CTNNB1,FYN,NFKBIA"]
["Interleukin-1 family signaling","1,17E00","1,55E-02",{"$error":"#NUM!"},"IL1R2,NFKBIA"]
["Formation of paraxial mesoderm","1,15E00","4,55E-02",{"$error":"#NUM!"},"CTNNB1"]
["Response to elevated platelet cytosolic Ca2+","1,15E00","1,52E-02",{"$error":"#NUM!"},"SERPINE1,TIMP3"]
["Gα12/13 Signaling","1,14E00","1,49E-02",{"$error":"#NUM!"},"CTNNB1,NFKBIA"]
["RAF-independent MAPK1/3 activation","1,13E00","4,35E-02",{"$error":"#NUM!"},"IL6"]
["Nephrin family interactions","1,13E00","4,35E-02",{"$error":"#NUM!"},"FYN"]
["NFE2L2 regulating anti-oxidant/detoxification enzymes","1,13E00","4,35E-02",{"$error":"#NUM!"},"GCLM"]
["Differential Regulation of Cytokine Production in Intestinal Epithelial Cells by IL-17A and IL-17F","1,13E00","4,35E-02",{"$error":"#NUM!"},"CCL2"]
["LPS/IL-1 Mediated Inhibition of RXR Function","1,12E00","1,01E-02",{"$error":"#NUM!"},"CD14,IL1R2,PLTP"]
["Sirtuin Signaling Pathway","1,12E00","1,01E-02",{"$error":"#NUM!"},"EPAS1,GADD45A,SOD2"]
["RHO GTPases Activate NADPH Oxidases","1,12E00","4,17E-02",{"$error":"#NUM!"},"S100A8"]
["Tumoricidal Function of Hepatic Natural Killer Cells","1,12E00","4,17E-02",{"$error":"#NUM!"},"ICAM1"]
["Incretin synthesis, secretion, and inactivation","1,1E00",0.04,{"$error":"#NUM!"},"CTNNB1"]
["Signaling by NTRK2 (TRKB)","1,1E00",0.04,{"$error":"#NUM!"},"FYN"]
["Putrescine Degradation III","1,1E00",0.04,{"$error":"#NUM!"},"SAT1"]
["Cellular Effects of Sildenafil (Viagra)","1,09E00","7,2E-03","-0,447","GPR84,IL6,NFKBIA,PTH1R,SOD2"]
["MSP-RON Signaling in Cancer Cells Pathway","1,09E00","1,4E-02",{"$error":"#NUM!"},"CTNNB1,NFKBIA"]
["DHCR24 Signaling Pathway","1,08E00","1,39E-02",{"$error":"#NUM!"},"APOD,PLTP"]
["Apelin Endothelial Signaling Pathway","1,08E00","1,39E-02",{"$error":"#NUM!"},"CCL2,ICAM1"]
["Bupropion Degradation","1,08E00","3,85E-02",{"$error":"#NUM!"},"CYP1B1"]
["Autism Signaling Pathway","1,08E00","9,71E-03",{"$error":"#NUM!"},"CCL2,CTNNB1,IL6"]
["C-type lectin receptors (CLRs)","1,08E00","1,38E-02",{"$error":"#NUM!"},"FYN,NFKBIA"]
["Endocannabinoid Cancer Inhibition Pathway","1,07E00","1,37E-02",{"$error":"#NUM!"},"CTNNB1,MMP2"]
["BMAL1:CLOCK,NPAS2 activates circadian gene expression","1,07E00","3,7E-02",{"$error":"#NUM!"},"SERPINE1"]
["Cardiogenesis","1,07E00","3,7E-02",{"$error":"#NUM!"},"CTNNB1"]
["Myogenesis","1,04E00","3,45E-02",{"$error":"#NUM!"},"CTNNB1"]
["Relaxin Signaling","1,02E00","1,28E-02",{"$error":"#NUM!"},"NFKBIA,PDE4B"]
["FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes","1,02E00","3,33E-02",{"$error":"#NUM!"},"SOD2"]
["Regulation of CDH11 Expression and Function","1,02E00","3,33E-02",{"$error":"#NUM!"},"CTNNB1"]
["Glutathione Redox Reactions I","1,02E00","3,33E-02",{"$error":"#NUM!"},"GPX3"]
["p75 NTR receptor-mediated signalling","1,02E00","1,27E-02",{"$error":"#NUM!"},"ARHGEF5,NFKBIA"]
["Epithelial Adherens Junction Signaling","1,02E00","1,27E-02",{"$error":"#NUM!"},"CTNNB1,FYN"]
["Microautophagy Signaling Pathway","1,01E00","1,26E-02",{"$error":"#NUM!"},"COL12A1,COL5A3"]
["Signaling by CSF1 (M-CSF) in myeloid cells","1,01E00","3,23E-02",{"$error":"#NUM!"},"FYN"]
["MyD88 dependent cascade initiated on endosome","1,01E00","3,23E-02",{"$error":"#NUM!"},"CD14"]
["Necroptosis Signaling Pathway","9,97E-01","1,23E-02",{"$error":"#NUM!"},"BIRC3,TNIP1"]
["Toll-like Receptor Cascades","9,97E-01","3,12E-02",{"$error":"#NUM!"},"CD14"]
["RIPK1-mediated regulated necrosis","9,97E-01","3,12E-02",{"$error":"#NUM!"},"BIRC3"]
["RHO GTPases activate IQGAPs","9,97E-01","3,12E-02",{"$error":"#NUM!"},"CTNNB1"]
["Toll Like Receptor 3 (TLR3) Cascade","9,84E-01","3,03E-02",{"$error":"#NUM!"},"BIRC3"]
["Airway Inflammation in Asthma","9,84E-01","3,03E-02",{"$error":"#NUM!"},"CCL2"]
["4-1BB Signaling in T Lymphocytes","9,72E-01","2,94E-02",{"$error":"#NUM!"},"NFKBIA"]
["Mitochondrial Dysfunction","9,72E-01","8,7E-03",{"$error":"#NUM!"},"BACE2,GPX3,SOD2"]
["Gαq Signaling","9,67E-01","1,18E-02",{"$error":"#NUM!"},"NFKBIA,RND3"]
["Signaling by the B Cell Receptor (BCR)","9,62E-01","1,18E-02",{"$error":"#NUM!"},"FYN,NFKBIA"]
["GPVI-mediated activation cascade","9,6E-01","2,86E-02",{"$error":"#NUM!"},"FYN"]
["Nucleotide catabolism","9,6E-01","2,86E-02",{"$error":"#NUM!"},"UPP1"]
["Germ Cell-Sertoli Cell Junction Signaling","9,58E-01","1,17E-02",{"$error":"#NUM!"},"CTNNB1,RND3"]
["Glioblastoma Multiforme Signaling","9,58E-01","1,17E-02",{"$error":"#NUM!"},"CTNNB1,RND3"]
["Th1 and Th2 Activation Pathway","9,37E-01","1,14E-02",{"$error":"#NUM!"},"ICAM1,IL6"]
["Gene and protein expression by JAK-STAT signaling after IL-12 stimulation","9,37E-01","2,7E-02",{"$error":"#NUM!"},"SOD2"]
["NF-κB Signaling","9,17E-01","7,01E-03","1,000","IL1R2,NFKBIA,TNFAIP3,TNIP1"]
["Formation of Fibrin Clot (Clotting Cascade)","9,16E-01","2,56E-02",{"$error":"#NUM!"},"THBD"]
["NGF-stimulated transcription","9,16E-01","2,56E-02",{"$error":"#NUM!"},"RRAD"]
["FLT3 Signaling","9,16E-01","2,56E-02",{"$error":"#NUM!"},"FYN"]
["Complement System","9,16E-01","2,56E-02",{"$error":"#NUM!"},"CFB"]
["Aryl Hydrocarbon Receptor Signaling","9,1E-01","1,09E-02",{"$error":"#NUM!"},"CYP1B1,IL6"]
["FAK Signaling","8,86E-01","5,77E-03","-0,816","CTNNB1,FYN,GPR84,IL1R2,MMP2,PTH1R"]
["April Mediated Signaling","8,86E-01","2,38E-02",{"$error":"#NUM!"},"NFKBIA"]
["Signaling by SCF-KIT","8,76E-01","2,33E-02",{"$error":"#NUM!"},"FYN"]
["DAP12 interactions","8,76E-01","2,33E-02",{"$error":"#NUM!"},"FYN"]
["Transport of vitamins, nucleosides, and related molecules","8,76E-01","2,33E-02",{"$error":"#NUM!"},"APOD"]
["B Cell Activating Factor Signaling","8,76E-01","2,33E-02",{"$error":"#NUM!"},"NFKBIA"]
["Regulation of the Epithelial-Mesenchymal Transition Pathway","8,69E-01","1,03E-02",{"$error":"#NUM!"},"CTNNB1,MMP2"]
["Regulation of the Epithelial Mesenchymal Transition by Growth Factors Pathway","8,69E-01","1,03E-02",{"$error":"#NUM!"},"IL6,MMP2"]
["Netrin-1 signaling","8,67E-01","2,27E-02",{"$error":"#NUM!"},"FYN"]
["TBC/RABGAPs","8,67E-01","2,27E-02",{"$error":"#NUM!"},"RAB6B"]
["Retinoid metabolism and transport","8,67E-01","2,27E-02",{"$error":"#NUM!"},"SDC2"]
["Acetone Degradation I (to Methylglyoxal)","8,67E-01","2,27E-02",{"$error":"#NUM!"},"CYP1B1"]
["CDX Gastrointestinal Cancer Signaling Pathway","8,58E-01","1,02E-02",{"$error":"#NUM!"},"CTNNB1,IL6"]
["Acetylcholine Receptor Signaling Pathway","8,58E-01","1,02E-02",{"$error":"#NUM!"},"FYN,IL6"]
["Arachidonic acid metabolism","8,58E-01","2,22E-02",{"$error":"#NUM!"},"CYP1B1"]
["RHO GTPases Activate WASPs and WAVEs","8,58E-01","2,22E-02",{"$error":"#NUM!"},"FYN"]
["tRNA Splicing","8,58E-01","2,22E-02",{"$error":"#NUM!"},"PDE4B"]
["ILK Signaling","8,55E-01","1,01E-02",{"$error":"#NUM!"},"CTNNB1,RND3"]
["Signaling by Retinoic Acid","8,49E-01","2,17E-02",{"$error":"#NUM!"},"PDK3"]
["IL-23 Signaling Pathway","8,49E-01","2,17E-02",{"$error":"#NUM!"},"NFKBIA"]
["Dendritic Cell Maturation","8,47E-01","6,59E-03","-2,000","COL5A3,ICAM1,IL6,NFKBIA"]
["Breast Cancer Regulation by Stathmin1","8,46E-01","6,58E-03","-1,000","ARHGEF5,GPR84,MMP2,PTH1R"]
["Adrenomedullin signaling pathway","8,41E-01","9,9E-03",{"$error":"#NUM!"},"ADM,MMP2"]
["Role of RIG1-like Receptors in Antiviral Innate Immunity","8,4E-01","2,13E-02",{"$error":"#NUM!"},"NFKBIA"]
["Estrogen Biosynthesis","8,4E-01","2,13E-02",{"$error":"#NUM!"},"CYP1B1"]
["Ephrin Receptor Signaling","8,37E-01","9,85E-03",{"$error":"#NUM!"},"FYN,SDC2"]
["Natural Killer Cell Signaling","8,34E-01","9,8E-03",{"$error":"#NUM!"},"COL5A3,FYN"]
["Fc epsilon receptor (FCERI) signaling","8,27E-01","9,71E-03",{"$error":"#NUM!"},"FYN,NFKBIA"]
["Antimicrobial peptides","8,24E-01","2,04E-02",{"$error":"#NUM!"},"S100A8"]
["TP53 Regulates Transcription of Cell Cycle Genes","8,24E-01","2,04E-02",{"$error":"#NUM!"},"GADD45A"]
["Pyruvate metabolism","8,24E-01","2,04E-02",{"$error":"#NUM!"},"PDK3"]
["T Cell Receptor Signaling","8,19E-01","6,42E-03",{"$error":"#NUM!"},"CTNNB1,FYN,ICAM1,NFKBIA"]
["Integrin Signaling","8,17E-01","9,57E-03",{"$error":"#NUM!"},"FYN,RND3"]
["Signaling by ERBB2","8,16E-01",0.02,{"$error":"#NUM!"},"FYN"]
["Protein Kinase A Signaling","8,15E-01","7,35E-03",{"$error":"#NUM!"},"CTNNB1,NFKBIA,PDE4B"]
["Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer","8,08E-01","1,96E-02",{"$error":"#NUM!"},"SERPINE1"]
["Transcriptional regulation by RUNX2","8,08E-01","1,96E-02",{"$error":"#NUM!"},"MMP13"]
["Transcriptional and post-translational regulation of MITF-M expression and activity","8,08E-01","1,96E-02",{"$error":"#NUM!"},"CTNNB1"]
["Amyloid Processing","8,08E-01","1,96E-02",{"$error":"#NUM!"},"BACE2"]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation","8,08E-01","1,96E-02",{"$error":"#NUM!"},"GADD45A"]
["Estrogen Receptor Signaling","8,06E-01","7,28E-03",{"$error":"#NUM!"},"MMP13,MMP2,SOD2"]
["B-WICH complex positively regulates rRNA expression",0.8,"1,92E-02",{"$error":"#NUM!"},"POLR1F"]
["Apoptotic execution phase",0.8,"1,92E-02",{"$error":"#NUM!"},"CTNNB1"]
["Multiple Sclerosis Signaling Pathway","7,89E-01","9,17E-03",{"$error":"#NUM!"},"CYP27B1,IL6"]
["Systemic Lupus Erythematosus in T Cell Signaling Pathway","7,81E-01","6,2E-03","0,000","CD44,GADD45A,IL6,RND3"]
["Signaling by PTK6","7,78E-01","1,82E-02",{"$error":"#NUM!"},"EPAS1"]
["Somitogenesis","7,78E-01","1,82E-02",{"$error":"#NUM!"},"CTNNB1"]
["Lymphotoxin β Receptor Signaling","7,78E-01","1,82E-02",{"$error":"#NUM!"},"NFKBIA"]
["Role of Cytokines in Mediating Communication between Immune Cells","7,78E-01","1,82E-02",{"$error":"#NUM!"},"IL6"]
["Thrombin Signaling","7,76E-01","9,01E-03",{"$error":"#NUM!"},"ARHGEF5,RND3"]
["Interleukin-3, Interleukin-5 and GM-CSF signaling","7,71E-01","1,79E-02",{"$error":"#NUM!"},"FYN"]
["CD27 Signaling in Lymphocytes","7,71E-01","1,79E-02",{"$error":"#NUM!"},"NFKBIA"]
["Nuclear Cytoskeleton Signaling Pathway","7,7E-01","8,93E-03",{"$error":"#NUM!"},"CTNNB1,FYN"]
["Role of NFAT in Cardiac Hypertrophy","7,58E-01","8,77E-03",{"$error":"#NUM!"},"IL6,RCAN1"]
["Metabolism of polyamines","7,5E-01","1,69E-02",{"$error":"#NUM!"},"SAT1"]
["Iron uptake and transport","7,43E-01","1,67E-02",{"$error":"#NUM!"},"FTH1"]
["Endometrial Cancer Signaling","7,43E-01","1,67E-02",{"$error":"#NUM!"},"CTNNB1"]
["GADD45 Signaling","7,43E-01","1,67E-02",{"$error":"#NUM!"},"GADD45A"]
["Visual phototransduction","7,37E-01","1,64E-02",{"$error":"#NUM!"},"STRA6"]
["MSP-RON Signaling Pathway","7,31E-01","1,61E-02",{"$error":"#NUM!"},"CCL2"]
["RHO GTPase cycle","7,28E-01","6,67E-03",{"$error":"#NUM!"},"ARHGEF5,PICALM,RND3"]
["cAMP-mediated signaling","7,21E-01","8,3E-03",{"$error":"#NUM!"},"PDE4B,PTH1R"]
["IL-12 Signaling and Production in Macrophages","7,19E-01","8,26E-03",{"$error":"#NUM!"},"APOD,S100A8"]
["Mitochondrial biogenesis","7,18E-01","1,56E-02",{"$error":"#NUM!"},"SOD2"]
["UFMylation Signaling Pathway","7,18E-01","1,56E-02",{"$error":"#NUM!"},"IL6"]
["RAB geranylgeranylation","7,12E-01","1,54E-02",{"$error":"#NUM!"},"RAB6B"]
["Role of JAK2 in Hormone-like Cytokine Signaling","7,12E-01","1,54E-02",{"$error":"#NUM!"},"BIRC3"]
["Pyridoxal 5'-phosphate Salvage Pathway","7,12E-01","1,54E-02",{"$error":"#NUM!"},"PDXK"]
["NoRC negatively regulates rRNA expression",0.7,"1,49E-02",{"$error":"#NUM!"},"POLR1F"]
["PXR/RXR Activation",0.7,"1,49E-02",{"$error":"#NUM!"},"IL6"]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",0.7,"1,49E-02",{"$error":"#NUM!"},"NFKBIA"]
["Pancreatic Secretion Signaling Pathway","6,95E-01","7,97E-03",{"$error":"#NUM!"},"ARHGEF5,CA12"]
["TNFR2 non-canonical NF-kB pathway","6,95E-01","1,47E-02",{"$error":"#NUM!"},"BIRC3"]
["SPINK1 General Cancer Pathway","6,95E-01","1,47E-02",{"$error":"#NUM!"},"IL6"]
["Phagosome Formation","6,79E-01","5,63E-03","-1,000","CD14,FYN,GPR84,PTH1R"]
["Basal Cell Carcinoma Signaling","6,78E-01","1,41E-02",{"$error":"#NUM!"},"CTNNB1"]
["Remodeling of Epithelial Adherens Junctions","6,78E-01","1,41E-02",{"$error":"#NUM!"},"CTNNB1"]
["Sperm Motility","6,77E-01","7,75E-03",{"$error":"#NUM!"},"FYN,PDE4B"]
["Cardiac Hypertrophy Signaling","6,72E-01","7,69E-03",{"$error":"#NUM!"},"IL6,RND3"]
["Ephrin B Signaling","6,67E-01","1,37E-02",{"$error":"#NUM!"},"CTNNB1"]
["Senescence-Associated Secretory Phenotype (SASP)","6,62E-01","1,35E-02",{"$error":"#NUM!"},"IL6"]
["RNA Polymerase I Transcription","6,62E-01","1,35E-02",{"$error":"#NUM!"},"POLR1F"]
["Extra-nuclear estrogen signaling","6,57E-01","1,33E-02",{"$error":"#NUM!"},"MMP2"]
["Nicotine Degradation III","6,57E-01","1,33E-02",{"$error":"#NUM!"},"CYP1B1"]
["Signaling by Rho Family GTPases","6,53E-01","7,46E-03",{"$error":"#NUM!"},"ARHGEF5,RND3"]
["Cellular response to hypoxia","6,52E-01","1,32E-02",{"$error":"#NUM!"},"EPAS1"]
["Plasma lipoprotein assembly, remodeling, and clearance","6,52E-01","1,32E-02",{"$error":"#NUM!"},"PLTP"]
["Macropinocytosis Signaling","6,52E-01","1,32E-02",{"$error":"#NUM!"},"CD14"]
["NF-κB Activation by Viruses","6,42E-01","1,28E-02",{"$error":"#NUM!"},"NFKBIA"]
["Maturity Onset Diabetes of Young (MODY) Signaling","6,42E-01","1,28E-02",{"$error":"#NUM!"},"APOD"]
["Role of WNT/GSK-3β Signaling in the Pathogenesis of Influenza","6,42E-01","1,28E-02",{"$error":"#NUM!"},"CTNNB1"]
["Hypoxia Signaling in the Cardiovascular System","6,42E-01","1,28E-02",{"$error":"#NUM!"},"NFKBIA"]
["Signaling by MET","6,37E-01","1,27E-02",{"$error":"#NUM!"},"COL5A3"]
["Thyroid Cancer Signaling","6,37E-01","1,27E-02",{"$error":"#NUM!"},"CTNNB1"]
["G alpha (12/13) signalling events","6,32E-01","1,25E-02",{"$error":"#NUM!"},"ARHGEF5"]
["Role of BRCA1 in DNA Damage Response","6,32E-01","1,25E-02",{"$error":"#NUM!"},"GADD45A"]
["Caveolar-mediated Endocytosis Signaling","6,32E-01","1,25E-02",{"$error":"#NUM!"},"FYN"]
["IL-7 Signaling Pathway","6,32E-01","1,25E-02",{"$error":"#NUM!"},"FYN"]
["Chemokine Signaling","6,27E-01","1,23E-02",{"$error":"#NUM!"},"CCL2"]
["Metabolism of water-soluble vitamins and cofactors","6,23E-01","1,22E-02",{"$error":"#NUM!"},"PDXK"]
["Eicosanoid Signaling","6,18E-01","7,07E-03",{"$error":"#NUM!"},"CTNNB1,MMP2"]
["Role of JAK family kinases in IL-6-type Cytokine Signaling","6,18E-01","1,2E-02",{"$error":"#NUM!"},"IL6"]
["Melatonin Degradation I","6,18E-01","1,2E-02",{"$error":"#NUM!"},"CYP1B1"]
["JAK/STAT Signaling","6,18E-01","1,2E-02",{"$error":"#NUM!"},"IL6"]
["PI Metabolism","6,14E-01","1,19E-02",{"$error":"#NUM!"},"TNFAIP8L3"]
["Transcriptional regulation of white adipocyte differentiation","6,14E-01","1,19E-02",{"$error":"#NUM!"},"ADIRF"]
["Transport of bile salts and organic acids, metal ions and amine compounds","6,14E-01","1,19E-02",{"$error":"#NUM!"},"SLC39A14"]
["Nicotine Degradation II","6,14E-01","1,19E-02",{"$error":"#NUM!"},"CYP1B1"]
["Role of MAPK Signaling in the Pathogenesis of Influenza","6,09E-01","1,18E-02",{"$error":"#NUM!"},"CCL2"]
["Regulation of the Epithelial Mesenchymal Transition in Development Pathway","6,05E-01","1,16E-02",{"$error":"#NUM!"},"CTNNB1"]
["HIPPO signaling",0.6,"1,15E-02",{"$error":"#NUM!"},"CD44"]
["Lung Ionic Balance Signaling Pathway","5,97E-01","5,7E-03",{"$error":"#NUM!"},"FYN,GPR84,PTH1R"]
["ABRA Signaling Pathway","5,96E-01","1,14E-02",{"$error":"#NUM!"},"IL6"]
["Superpathway of Melatonin Degradation","5,92E-01","1,12E-02",{"$error":"#NUM!"},"CYP1B1"]
["Opioid Signalling","5,88E-01","1,11E-02",{"$error":"#NUM!"},"PDE4B"]
["RAB GEFs exchange GTP for GDP on RABs","5,88E-01","1,11E-02",{"$error":"#NUM!"},"RAB6B"]
["Degradation of beta-catenin by the destruction complex","5,84E-01","1,1E-02",{"$error":"#NUM!"},"CTNNB1"]
["MAPK6/MAPK4 signaling","5,8E-01","1,09E-02",{"$error":"#NUM!"},"MMP2"]
["Actin Nucleation by ARP-WASP Complex","5,8E-01","1,09E-02",{"$error":"#NUM!"},"RND3"]
["Post-translational modification: synthesis of GPI-anchored proteins","5,76E-01","1,08E-02",{"$error":"#NUM!"},"MDGA1"]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes","5,76E-01","1,08E-02",{"$error":"#NUM!"},"FYN"]
["Apelin Adipocyte Signaling Pathway","5,76E-01","1,08E-02",{"$error":"#NUM!"},"GPX3"]
["MITF-M-dependent gene expression","5,68E-01","1,05E-02",{"$error":"#NUM!"},"CTNNB1"]
["Immunogenic Cell Death Signaling Pathway","5,64E-01","1,04E-02",{"$error":"#NUM!"},"IL6"]
["Transcriptional regulation by RUNX3","5,64E-01","1,04E-02",{"$error":"#NUM!"},"CTNNB1"]
["Prolactin Signaling","5,64E-01","1,04E-02",{"$error":"#NUM!"},"FYN"]
["IL-1 Signaling","5,6E-01","1,03E-02",{"$error":"#NUM!"},"NFKBIA"]
["TGF-β Signaling","5,6E-01","1,03E-02",{"$error":"#NUM!"},"SERPINE1"]
["DNA Methylation and Transcriptional Repression Signaling","5,56E-01","1,02E-02",{"$error":"#NUM!"},"GADD45A"]
["Small Cell Lung Cancer Signaling","5,56E-01","1,02E-02",{"$error":"#NUM!"},"NFKBIA"]
["Crosstalk between Dendritic Cells and Natural Killer Cells","5,56E-01","1,02E-02",{"$error":"#NUM!"},"IL6"]
["Mouse Embryonic Stem Cell Pluripotency","5,38E-01","9,71E-03",{"$error":"#NUM!"},"CTNNB1"]
["Cargo recognition for clathrin-mediated endocytosis","5,31E-01","9,52E-03",{"$error":"#NUM!"},"PICALM"]
["Sleep REM Signaling Pathway","5,28E-01","9,43E-03",{"$error":"#NUM!"},"IL6"]
["IL-4 Signaling","5,26E-01","5,21E-03",{"$error":"#NUM!"},"COL12A1,COL5A3,TIMP3"]
["Myelination Signaling Pathway","5,25E-01","6,06E-03",{"$error":"#NUM!"},"CTNNB1,FYN"]
["Xenobiotic Metabolism Signaling","5,25E-01","6,06E-03",{"$error":"#NUM!"},"CYP1B1,IL6"]
["WNK Renal Signaling Pathway","5,24E-01","9,35E-03",{"$error":"#NUM!"},"BIRC3"]
["Gap Junction Signaling","5,18E-01","5,99E-03",{"$error":"#NUM!"},"CTNNB1,IL1R2"]
["ISGylation Signaling Pathway","5,17E-01","9,17E-03",{"$error":"#NUM!"},"IL6"]
["Phase II - Conjugation of compounds","5,17E-01","9,17E-03",{"$error":"#NUM!"},"GCLM"]
["mRNA 3 Prime End Processing Signaling Pathway","5,08E-01","8,93E-03",{"$error":"#NUM!"},"CD44"]
["Regulation of Actin-based Motility by Rho","5,08E-01","8,93E-03",{"$error":"#NUM!"},"RND3"]
["O-linked glycosylation","5,04E-01","8,85E-03",{"$error":"#NUM!"},"THBS2"]
["Binding and Uptake of Ligands by Scavenger Receptors","5,01E-01","8,77E-03",{"$error":"#NUM!"},"FTH1"]
["Role of MAPK Signaling in Promoting the Pathogenesis of Influenza","4,98E-01","8,7E-03",{"$error":"#NUM!"},"NFKBIA"]
["Amyotrophic Lateral Sclerosis Signaling","4,95E-01","8,62E-03",{"$error":"#NUM!"},"BIRC3"]
["Cholecystokinin/Gastrin-mediated Signaling","4,92E-01","8,55E-03",{"$error":"#NUM!"},"RND3"]
["Sphingosine-1-phosphate Signaling","4,89E-01","8,47E-03",{"$error":"#NUM!"},"RND3"]
["Antioxidant Action of Vitamin C","4,86E-01","8,4E-03",{"$error":"#NUM!"},"NFKBIA"]
["Fc Epsilon RI Signaling","4,83E-01","8,33E-03",{"$error":"#NUM!"},"FYN"]
["Virus Entry via Endocytic Pathways","4,83E-01","8,33E-03",{"$error":"#NUM!"},"FYN"]
["Renin-Angiotensin Signaling","4,8E-01","8,26E-03",{"$error":"#NUM!"},"CCL2"]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency","4,74E-01","8,13E-03",{"$error":"#NUM!"},"CTNNB1"]
["p38 MAPK Signaling","4,71E-01","8,06E-03",{"$error":"#NUM!"},"IL1R2"]
["TCR signaling","4,66E-01","7,94E-03",{"$error":"#NUM!"},"NFKBIA"]
["Gαs Signaling","4,66E-01","7,94E-03",{"$error":"#NUM!"},"PTH1R"]
["Endocannabinoid Developing Neuron Pathway","4,63E-01","7,87E-03",{"$error":"#NUM!"},"CTNNB1"]
["MHC class II antigen presentation","4,6E-01","7,81E-03",{"$error":"#NUM!"},"LGMN"]
["Clathrin-mediated endocytosis","4,58E-01","7,75E-03",{"$error":"#NUM!"},"PICALM"]
["Costimulation by the CD28 family","4,5E-01","7,58E-03",{"$error":"#NUM!"},"FYN"]
["HGF Signaling","4,5E-01","7,58E-03",{"$error":"#NUM!"},"IL6"]
["fMLP Signaling in Neutrophils","4,47E-01","7,52E-03",{"$error":"#NUM!"},"NFKBIA"]
["IL-27 Signaling Pathway","4,44E-01","7,46E-03",{"$error":"#NUM!"},"IL1R2"]
["Class I MHC mediated antigen processing and presentation","4,44E-01","5,25E-03",{"$error":"#NUM!"},"CD14,S100A8"]
["Complement cascade","4,39E-01","7,35E-03",{"$error":"#NUM!"},"CFB"]
["Hereditary Breast Cancer Signaling","4,34E-01","7,25E-03",{"$error":"#NUM!"},"GADD45A"]
["RAC Signaling","4,34E-01","7,25E-03",{"$error":"#NUM!"},"CD44"]
["Adipogenesis pathway","4,34E-01","7,25E-03",{"$error":"#NUM!"},"CTNNB1"]
["Role of PKR in Interferon Induction and Antiviral Response","4,32E-01","7,19E-03",{"$error":"#NUM!"},"NFKBIA"]
["STAT3 Pathway","4,32E-01","7,19E-03",{"$error":"#NUM!"},"IL1R2"]
["Insulin Receptor Signaling","4,29E-01","7,14E-03",{"$error":"#NUM!"},"FYN"]
["Th2 Pathway","4,27E-01","7,09E-03",{"$error":"#NUM!"},"ICAM1"]
["PIP3 activates AKT signaling","4,13E-01","6,8E-03",{"$error":"#NUM!"},"FYN"]
["NAD Signaling Pathway","4,06E-01","6,67E-03",{"$error":"#NUM!"},"SOD2"]
["Factors Promoting Cardiogenesis in Vertebrates","4,04E-01","6,62E-03",{"$error":"#NUM!"},"CTNNB1"]
["Type II Diabetes Mellitus Signaling","4,02E-01","6,58E-03",{"$error":"#NUM!"},"NFKBIA"]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses","3,97E-01","6,49E-03",{"$error":"#NUM!"},"IL6"]
["Transcriptional Regulatory Network in Embryonic Stem Cells","3,76E-01","6,1E-03",{"$error":"#NUM!"},"CTNNB1"]
["Fcgamma receptor (FCGR) dependent phagocytosis","3,72E-01","6,02E-03",{"$error":"#NUM!"},"FYN"]
["CXCR4 Signaling","3,7E-01","5,99E-03",{"$error":"#NUM!"},"RND3"]
["Phagosome Maturation","3,63E-01","5,85E-03",{"$error":"#NUM!"},"LAMP1"]
["Systemic Lupus Erythematosus in B Cell Signaling Pathway","3,61E-01","4,12E-03",{"$error":"#NUM!"},"CTNNB1,FYN,IL6"]
["Netrin Signaling","3,57E-01","5,75E-03",{"$error":"#NUM!"},"FYN"]
["Cardiac β-adrenergic Signaling","3,46E-01","5,56E-03",{"$error":"#NUM!"},"PDE4B"]
["Tight Junction Signaling","3,45E-01","5,52E-03",{"$error":"#NUM!"},"CTNNB1"]
["Protein Sorting Signaling Pathway","3,43E-01","5,49E-03",{"$error":"#NUM!"},"FYN"]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes","3,38E-01","4,28E-03",{"$error":"#NUM!"},"FYN,NFKBIA"]
["MicroRNA Biogenesis Signaling Pathway","3,33E-01","5,32E-03",{"$error":"#NUM!"},"ZC3H12A"]
["GNRH Signaling","3,26E-01","5,21E-03",{"$error":"#NUM!"},"MMP2"]
["Adrenergic Receptor Signaling Pathway (Enhanced)","3,18E-01","5,08E-03",{"$error":"#NUM!"},"IL6"]
["TCF dependent signaling in response to WNT","3,16E-01","5,05E-03",{"$error":"#NUM!"},"CTNNB1"]
["Human Embryonic Stem Cell Pluripotency","3,12E-01","4,98E-03",{"$error":"#NUM!"},"CTNNB1"]
["Oxytocin in Brain Signaling Pathway","3,1E-01","4,95E-03",{"$error":"#NUM!"},"IL6"]
["BBSome Signaling Pathway","3,1E-01","4,04E-03",{"$error":"#NUM!"},"GPR84,PTH1R"]
["Intra-Golgi and retrograde Golgi-to-ER traffic","3,07E-01","4,9E-03",{"$error":"#NUM!"},"RAB6B"]
["Beta-catenin independent WNT signaling","3,06E-01","4,88E-03",{"$error":"#NUM!"},"CTNNB1"]
["Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","2,91E-01","4,65E-03",{"$error":"#NUM!"},"ICAM1"]
["mTOR Signaling","2,91E-01","4,65E-03",{"$error":"#NUM!"},"RND3"]
["Calcium Signaling","2,87E-01","4,59E-03",{"$error":"#NUM!"},"RCAN1"]
["CD28 Signaling in T Helper Cells","2,86E-01","3,83E-03",{"$error":"#NUM!"},"FYN,NFKBIA"]
["Autophagy","2,85E-01","4,55E-03",{"$error":"#NUM!"},"LAMP1"]
["ERK/MAPK Signaling","2,83E-01","4,52E-03",{"$error":"#NUM!"},"FYN"]
["NAFLD Signaling Pathway","2,78E-01","4,44E-03",{"$error":"#NUM!"},"IL6"]
["Orexin Signaling Pathway","2,58E-01","4,15E-03",{"$error":"#NUM!"},"IL6"]
["Actin Cytoskeleton Signaling","2,56E-01","4,12E-03",{"$error":"#NUM!"},"CD14"]
["PKCθ Signaling in T Lymphocytes","2,55E-01","3,57E-03",{"$error":"#NUM!"},"FYN,NFKBIA"]
["Neddylation","2,52E-01","4,07E-03",{"$error":"#NUM!"},"EPAS1"]
["TRIM21 Intracellular Antibody Signaling Pathway","2,5E-01","3,53E-03",{"$error":"#NUM!"},"CTNNB1,IL6"]
["Docosahexaenoic Acid (DHA) Signaling","2,46E-01","3,97E-03",{"$error":"#NUM!"},"BIRC3"]
["TEC Kinase Signaling","2,41E-01","3,45E-03",{"$error":"#NUM!"},"FYN,RND3"]
["RAF/MAP kinase cascade","2,35E-01","3,82E-03",{"$error":"#NUM!"},"FYN"]
["PI3K Signaling in B Lymphocytes","2,32E-01","3,38E-03",{"$error":"#NUM!"},"FYN,NFKBIA"]
["Circadian Rhythm Signaling","2,24E-01","3,66E-03",{"$error":"#NUM!"},"FYN"]
["Protein Ubiquitination Pathway","2,18E-01","3,58E-03",{"$error":"#NUM!"},"BIRC3"]
["Chronic Myeloid Leukemia Signaling","2,16E-01","3,56E-03",{"$error":"#NUM!"},"CTNNB1"]
["Oxytocin Signaling Pathway","2,12E-01","3,51E-03",{"$error":"#NUM!"},"IL6"]
["Insulin Secretion Signaling Pathway","2,12E-01","3,51E-03",{"$error":"#NUM!"},"FYN"]
["CLEAR Signaling Pathway","2,11E-01","3,5E-03",{"$error":"#NUM!"},"LAMP1"]
["Histone Modification Signaling Pathway","1,99E-01","3,33E-03",{"$error":"#NUM!"},"MMP2"]
["NFKBIE Signaling Pathway",0,"2,23E-03",{"$error":"#NUM!"},"NFKBIA"]
["Class A/1 (Rhodopsin-like receptors)",0,0.003,{"$error":"#NUM!"},"CCL2"]
["Role of NFAT in Regulation of the Immune Response",0,"2,86E-03",{"$error":"#NUM!"},"FYN,NFKBIA,RCAN1"]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0,"1,63E-03",{"$error":"#NUM!"},"FYN"]
["T Helper Cell Differentiation",0,"2,11E-03",{"$error":"#NUM!"},"IL6"]
["ICOS-ICOSL Signaling in T Helper Cells",0,"1,95E-03",{"$error":"#NUM!"},"NFKBIA"]
["CREB Signaling in Neurons",0,"3,24E-03",{"$error":"#NUM!"},"GPR84,PTH1R"]
["Type I Diabetes Mellitus Signaling",0,"1,95E-03",{"$error":"#NUM!"},"NFKBIA"]
["Graft-versus-Host Disease Signaling",0,"2,23E-03",{"$error":"#NUM!"},"IL6"]
["Communication between Innate and Adaptive Immune Cells",0,"1,06E-03",{"$error":"#NUM!"},"IL6"]
["Systemic Lupus Erythematosus Signaling",0,"9,37E-04",{"$error":"#NUM!"},"IL6"]
["Phospholipase C Signaling",0,"2,67E-03",{"$error":"#NUM!"},"ARHGEF5,FYN,RND3"]
["Altered T Cell and B Cell Signaling in Rheumatoid Arthritis",0,"1,06E-03",{"$error":"#NUM!"},"IL6"]
["OX40 Signaling Pathway",0,"2,07E-03",{"$error":"#NUM!"},"NFKBIA"]
["Hematopoiesis from Pluripotent Stem Cells",0,"2,23E-03",{"$error":"#NUM!"},"IL6"]
["Parkinson's Signaling Pathway",0,"3,16E-03",{"$error":"#NUM!"},"IL6"]
["SAPK/JNK Signaling",0,"1,99E-03",{"$error":"#NUM!"},"GADD45A"]
["B Cell Receptor Signaling",0,"1,56E-03",{"$error":"#NUM!"},"NFKBIA"]
["Th17 Activation Pathway",0,"2,04E-03",{"$error":"#NUM!"},"IL6"]
["T Cell Exhaustion Signaling Pathway",0,"1,76E-03",{"$error":"#NUM!"},"IL6"]