{"text_format":"3","workbook":"xls","n_sheets":5,"sheets":["Canonical Pathways","Functions and disease","Specific functions","Tox functions","Networks"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Canonical Pathways","index":0,"n_rows":149,"n_cols":4,"rows_kept":149,"flags":["formulas_cached_only"]}
["© 2000-2016 QIAGEN. All rights reserved."]
["Ingenuity Canonical Pathways"," -log(p-value)","Ratio","Molecules"]
["Clathrin-mediated Endocytosis Signaling",{"v":10.1,"d":"1.01E+01"},{"v":0.0426,"d":"4.26E-02"},"ACTR2,ALB,ACTR3,CDC42,ARPC2,ACTB,ACTG1,RBP4"]
["Signaling by Rho Family GTPases",{"v":9.29,"d":"9.29E+00"},{"v":0.0339,"d":"3.39E-02"},"GNAI2,ACTR2,ACTR3,CDC42,ARPC2,ACTB,VIM,ACTG1"]
["RhoGDI Signaling",{"v":8.57,"d":"8.57E+00"},{"v":0.0391,"d":"3.91E-02"},"GNAI2,ACTR2,ACTR3,CDC42,ARPC2,ACTB,ACTG1"]
["Remodeling of Epithelial Adherens Junctions",{"v":7.58,"d":"7.58E+00"},{"v":0.0735,"d":"7.35E-02"},"ACTR2,ACTR3,ARPC2,ACTB,ACTG1"]
["Regulation of Actin-based Motility by Rho",{"v":6.89,"d":"6.89E+00"},{"v":0.0538,"d":"5.38E-02"},"ACTR2,ACTR3,CDC42,ARPC2,ACTB"]
["Integrin Signaling",{"v":6.6,"d":"6.60E+00"},{"v":0.0288,"d":"2.88E-02"},"ACTR2,ACTR3,CDC42,ARPC2,ACTB,ACTG1"]
["Actin Cytoskeleton Signaling",{"v":6.46,"d":"6.46E+00"},{"v":0.0273,"d":"2.73E-02"},"ACTR2,ACTR3,CDC42,ARPC2,ACTB,ACTG1"]
["fMLP Signaling in Neutrophils",{"v":6.43,"d":"6.43E+00"},{"v":0.0435,"d":"4.35E-02"},"GNAI2,ACTR2,ACTR3,CDC42,ARPC2"]
["RhoA Signaling",{"v":6.27,"d":"6.27E+00"},{"v":0.0403,"d":"4.03E-02"},"ACTR2,ACTR3,ARPC2,ACTB,ACTG1"]
["Actin Nucleation by ARP-WASP Complex",{"v":6.08,"d":"6.08E+00"},{"v":0.0714,"d":"7.14E-02"},"ACTR2,ACTR3,CDC42,ARPC2"]
["Agrin Interactions at Neuromuscular Junction",{"v":5.69,"d":"5.69E+00"},{"v":0.0571,"d":"5.71E-02"},"LAMC1,CDC42,ACTB,ACTG1"]
["Ephrin Receptor Signaling",{"v":5.51,"d":"5.51E+00"},{"v":0.0282,"d":"2.82E-02"},"GNAI2,ACTR2,ACTR3,CDC42,ARPC2"]
["Rac Signaling",{"v":4.96,"d":"4.96E+00"},{"v":0.0374,"d":"3.74E-02"},"ACTR2,ACTR3,CDC42,ARPC2"]
["CD28 Signaling in T Helper Cells",{"v":4.72,"d":"4.72E+00"},{"v":0.0325,"d":"3.25E-02"},"ACTR2,ACTR3,CDC42,ARPC2"]
["Cdc42 Signaling",{"v":4.18,"d":"4.18E+00"},{"v":0.0237,"d":"2.37E-02"},"ACTR2,ACTR3,CDC42,ARPC2"]
["ILK Signaling",{"v":4.01,"d":"4.01E+00"},{"v":0.0214,"d":"2.14E-02"},"CDC42,ACTB,VIM,ACTG1"]
["Caveolar-mediated Endocytosis Signaling",{"v":3.93,"d":"3.93E+00"},{"v":0.0411,"d":"4.11E-02"},"ALB,ACTB,ACTG1"]
["Leukocyte Extravasation Signaling",{"v":3.86,"d":"3.86E+00"},{"v":0.0196,"d":"1.96E-02"},"GNAI2,CDC42,ACTB,ACTG1"]
["Death Receptor Signaling",{"v":3.63,"d":"3.63E+00"},{"v":0.0326,"d":"3.26E-02"},"ACTB,ACTG1,HSPB1"]
["Axonal Guidance Signaling",{"v":3.62,"d":"3.62E+00"},{"v":0.0114,"d":"1.14E-02"},"GNAI2,ACTR2,ACTR3,CDC42,ARPC2"]
["Virus Entry via Endocytic Pathways",{"v":3.59,"d":"3.59E+00"},{"v":0.0316,"d":"3.16E-02"},"CDC42,ACTB,ACTG1"]
["Paxillin Signaling",{"v":3.51,"d":"3.51E+00"},{"v":0.0297,"d":"2.97E-02"},"CDC42,ACTB,ACTG1"]
["LXR/RXR Activation",{"v":3.21,"d":"3.21E+00"},{"v":0.0234,"d":"2.34E-02"},"ALB,HADH,RBP4"]
["Tec Kinase Signaling",{"v":2.93,"d":"2.93E+00"},{"v":0.0188,"d":"1.88E-02"},"GNAI2,ACTB,ACTG1"]
["Germ Cell-Sertoli Cell Junction Signaling",{"v":2.91,"d":"2.91E+00"},{"v":0.0184,"d":"1.84E-02"},"CDC42,ACTB,ACTG1"]
["Mechanisms of Viral Exit from Host Cells",{"v":2.88,"d":"2.88E+00"},{"v":0.0488,"d":"4.88E-02"},"ACTB,ACTG1"]
["Tight Junction Signaling",{"v":2.88,"d":"2.88E+00"},{"v":0.018,"d":"1.80E-02"},"CDC42,ACTB,ACTG1"]
["Gap Junction Signaling",{"v":2.87,"d":"2.87E+00"},{"v":0.0179,"d":"1.79E-02"},"GNAI2,ACTB,ACTG1"]
["NRF2-mediated Oxidative Stress Response",{"v":2.78,"d":"2.78E+00"},{"v":0.0167,"d":"1.67E-02"},"ACTB,ACTG1,GSTP1"]
["MSP-RON Signaling Pathway",{"v":2.76,"d":"2.76E+00"},{"v":0.0426,"d":"4.26E-02"},"ACTB,ACTG1"]
["Sertoli Cell-Sertoli Cell Junction Signaling",{"v":2.74,"d":"2.74E+00"},{"v":0.0161,"d":"1.61E-02"},"CDC42,ACTB,ACTG1"]
["Agranulocyte Adhesion and Diapedesis",{"v":2.72,"d":"2.72E+00"},{"v":0.0158,"d":"1.58E-02"},"GNAI2,ACTB,ACTG1"]
["Ephrin B Signaling",{"v":2.36,"d":"2.36E+00"},{"v":0.0267,"d":"2.67E-02"},"GNAI2,CDC42"]
["Protein Ubiquitination Pathway",{"v":2.34,"d":"2.34E+00"},{"v":0.0116,"d":"1.16E-02"},"PSMA6,PSMA1,HSPB1"]
["Crosstalk between Dendritic Cells and Natural Killer Cells",{"v":2.21,"d":"2.21E+00"},{"v":0.0222,"d":"2.22E-02"},"ACTB,ACTG1"]
["FAK Signaling",{"v":2.21,"d":"2.21E+00"},{"v":0.0222,"d":"2.22E-02"},"ACTB,ACTG1"]
["G Beta Gamma Signaling",{"v":2.14,"d":"2.14E+00"},{"v":0.0204,"d":"2.04E-02"},"GNAI2,CDC42"]
["VEGF Signaling",{"v":2.14,"d":"2.14E+00"},{"v":0.0204,"d":"2.04E-02"},"ACTB,ACTG1"]
["Androgen Signaling",{"v":2.01,"d":"2.01E+00"},{"v":0.0175,"d":"1.75E-02"},"GNAI2,CALR"]
["Corticotropin Releasing Hormone Signaling",{"v":1.96,"d":"1.96E+00"},{"v":0.0165,"d":"1.65E-02"},"GNAI2,KRT1"]
["Atherosclerosis Signaling",{"v":1.94,"d":"1.94E+00"},{"v":0.016,"d":"1.60E-02"},"ALB,RBP4"]
["Guanine and Guanosine Salvage I",{"v":1.93,"d":"1.93E+00"},{"v":0.111,"d":"1.11E-01"},"HPRT1"]
["GNRH Signaling",{"v":1.87,"d":"1.87E+00"},{"v":0.0148,"d":"1.48E-02"},"GNAI2,CDC42"]
["FXR/RXR Activation",{"v":1.86,"d":"1.86E+00"},{"v":0.0146,"d":"1.46E-02"},"ALB,RBP4"]
["IL-12 Signaling and Production in Macrophages",{"v":1.86,"d":"1.86E+00"},{"v":0.0146,"d":"1.46E-02"},"ALB,RBP4"]
["Rapoport-Luebering Glycolytic Shunt",{"v":1.84,"d":"1.84E+00"},{"v":0.0909,"d":"9.09E-02"},"PGAM1"]
["Cellular Effects of Sildenafil (Viagra)",{"v":1.83,"d":"1.83E+00"},{"v":0.0141,"d":"1.41E-02"},"ACTB,ACTG1"]
["Aryl Hydrocarbon Receptor Signaling",{"v":1.81,"d":"1.81E+00"},{"v":0.0137,"d":"1.37E-02"},"GSTP1,HSPB1"]
["L-DOPA Degradation",{"v":1.77,"d":"1.77E+00"},{"v":0.0769,"d":"7.69E-02"},"COMT"]
["Calcium Transport I",{"v":1.74,"d":"1.74E+00"},{"v":0.0714,"d":"7.14E-02"},"ANXA5"]
["Galactose Degradation I (Leloir Pathway)",{"v":1.74,"d":"1.74E+00"},{"v":0.0714,"d":"7.14E-02"},"GALM"]
["Acute Phase Response Signaling",{"v":1.68,"d":"1.68E+00"},{"v":0.0117,"d":"1.17E-02"},"ALB,RBP4"]
["Adenine and Adenosine Salvage III",{"v":1.66,"d":"1.66E+00"},{"v":0.0588,"d":"5.88E-02"},"HPRT1"]
["Granulocyte Adhesion and Diapedesis",{"v":1.64,"d":"1.64E+00"},{"v":0.0112,"d":"1.12E-02"},"GNAI2,HSPB1"]
["B Cell Receptor Signaling",{"v":1.64,"d":"1.64E+00"},{"v":0.0112,"d":"1.12E-02"},"IGHG3,CDC42"]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",{"v":1.61,"d":"1.61E+00"},{"v":0.0108,"d":"1.08E-02"},"ALB,RBP4"]
["Sucrose Degradation V (Mammalian)",{"v":1.61,"d":"1.61E+00"},{"v":0.0526,"d":"5.26E-02"},"GALM"]
["Endoplasmic Reticulum Stress Pathway",{"v":1.57,"d":"1.57E+00"},{"v":0.0476,"d":"4.76E-02"},"CALR"]
["RAR Activation",{"v":1.56,"d":"1.56E+00"},{"v":0.0102,"d":"1.02E-02"},"ACTB,RBP4"]
["Breast Cancer Regulation by Stathmin1",{"v":1.56,"d":"1.56E+00"},{"v":0.0102,"d":"1.02E-02"},"GNAI2,CDC42"]
["Glutaryl-CoA Degradation",{"v":1.53,"d":"1.53E+00"},{"v":0.0435,"d":"4.35E-02"},"HADH"]
["Tumoricidal Function of Hepatic Natural Killer Cells",{"v":1.51,"d":"1.51E+00"},{"v":0.0417,"d":"4.17E-02"},"SERPINB9"]
["Lipid Antigen Presentation by CD1",{"v":1.48,"d":"1.48E+00"},{"v":0.0385,"d":"3.85E-02"},"CALR"]
["Cardiac Hypertrophy Signaling",{"v":1.43,"d":"1.43E+00"},{"v":0.00862,"d":"8.62E-03"},"GNAI2,HSPB1"]
["Antigen Presentation Pathway",{"v":1.33,"d":"1.33E+00"},{"v":0.027,"d":"2.70E-02"},"CALR"]
["Glutathione-mediated Detoxification",{"v":1.29,"d":"1.29E+00"},{"v":0.025,"d":"2.50E-02"},"GSTP1"]
["Glycolysis I",{"v":1.28,"d":"1.28E+00"},{"v":0.0244,"d":"2.44E-02"},"PGAM1"]
["Dopamine Degradation",{"v":1.27,"d":"1.27E+00"},{"v":0.0238,"d":"2.38E-02"},"COMT"]
["Fatty Acid β-oxidation I",{"v":1.24,"d":"1.24E+00"},{"v":0.0222,"d":"2.22E-02"},"HADH"]
["Tryptophan Degradation III (Eukaryotic)",{"v":1.23,"d":"1.23E+00"},{"v":0.0217,"d":"2.17E-02"},"HADH"]
["Gluconeogenesis I",{"v":1.23,"d":"1.23E+00"},{"v":0.0217,"d":"2.17E-02"},"PGAM1"]
["Hematopoiesis from Pluripotent Stem Cells",{"v":1.22,"d":"1.22E+00"},{"v":0.0213,"d":"2.13E-02"},"IGHG3"]
["Primary Immunodeficiency Signaling",{"v":1.22,"d":"1.22E+00"},{"v":0.0208,"d":"2.08E-02"},"IGHG3"]
["Autoimmune Thyroid Disease Signaling",{"v":1.21,"d":"1.21E+00"},{"v":0.0204,"d":"2.04E-02"},"IGHG3"]
["TNFR1 Signaling",{"v":1.21,"d":"1.21E+00"},{"v":0.0204,"d":"2.04E-02"},"CDC42"]
["Ephrin A Signaling",{"v":1.2,"d":"1.20E+00"},"2E-02","CDC42"]
["Unfolded protein response",{"v":1.17,"d":"1.17E+00"},{"v":0.0185,"d":"1.85E-02"},"CALR"]
["Noradrenaline and Adrenaline Degradation",{"v":1.16,"d":"1.16E+00"},{"v":0.0182,"d":"1.82E-02"},"COMT"]
["PCP pathway",{"v":1.1,"d":"1.10E+00"},{"v":0.0159,"d":"1.59E-02"},"HSPB1"]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",{"v":1.09,"d":"1.09E+00"},{"v":0.0154,"d":"1.54E-02"},"GNAI2"]
["Molecular Mechanisms of Cancer",{"v":1.07,"d":"1.07E+00"},{"v":0.00536,"d":"5.36E-03"},"GNAI2,CDC42"]
["Macropinocytosis Signaling",{"v":1.07,"d":"1.07E+00"},{"v":0.0147,"d":"1.47E-02"},"CDC42"]
["GDNF Family Ligand-Receptor Interactions",{"v":1.05,"d":"1.05E+00"},{"v":0.0141,"d":"1.41E-02"},"CDC42"]
["Neurotrophin/TRK Signaling",{"v":1.05,"d":"1.05E+00"},{"v":0.0139,"d":"1.39E-02"},"CDC42"]
["LPS-stimulated MAPK Signaling",{"v":1.04,"d":"1.04E+00"},{"v":0.0137,"d":"1.37E-02"},"CDC42"]
["Renal Cell Carcinoma Signaling",{"v":1.04,"d":"1.04E+00"},{"v":0.0137,"d":"1.37E-02"},"CDC42"]
["CCR5 Signaling in Macrophages",{"v":1.03,"d":"1.03E+00"},{"v":0.0135,"d":"1.35E-02"},"GNAI2"]
["Chemokine Signaling",{"v":1.03,"d":"1.03E+00"},{"v":0.0133,"d":"1.33E-02"},"GNAI2"]
["Melatonin Signaling",{"v":1.02,"d":"1.02E+00"},{"v":0.0132,"d":"1.32E-02"},"GNAI2"]
["HER-2 Signaling in Breast Cancer",{"v":1.02,"d":"1.02E+00"},{"v":0.0132,"d":"1.32E-02"},"CDC42"]
["Role of BRCA1 in DNA Damage Response",{"v":1.01,"d":"1.01E+00"},{"v":0.0128,"d":"1.28E-02"},"ACTB"]
["GPCR-Mediated Integration of Enteroendocrine Signaling Exemplified by an L Cell",{"v":1.01,"d":"1.01E+00"},{"v":0.0127,"d":"1.27E-02"},"GNAI2"]
["Allograft Rejection Signaling",{"v":0.977,"d":"9.77E-01"},{"v":0.0118,"d":"1.18E-02"},"IGHG3"]
["Prostate Cancer Signaling",{"v":0.972,"d":"9.72E-01"},{"v":0.0116,"d":"1.16E-02"},"GSTP1"]
["ErbB Signaling",{"v":0.972,"d":"9.72E-01"},{"v":0.0116,"d":"1.16E-02"},"CDC42"]
["TGF-β Signaling",{"v":0.967,"d":"9.67E-01"},{"v":0.0115,"d":"1.15E-02"},"CDC42"]
["Communication between Innate and Adaptive Immune Cells",{"v":0.953,"d":"9.53E-01"},{"v":0.0111,"d":"1.11E-02"},"IGHG3"]
["PAK Signaling",{"v":0.949,"d":"9.49E-01"},{"v":0.011,"d":"1.10E-02"},"CDC42"]
["GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells",{"v":0.949,"d":"9.49E-01"},{"v":0.011,"d":"1.10E-02"},"GNAI2"]
["Dopamine Receptor Signaling",{"v":0.944,"d":"9.44E-01"},{"v":0.0109,"d":"1.09E-02"},"COMT"]
["IL-1 Signaling",{"v":0.936,"d":"9.36E-01"},{"v":0.0106,"d":"1.06E-02"},"GNAI2"]
["SAPK/JNK Signaling",{"v":0.931,"d":"9.31E-01"},{"v":0.0105,"d":"1.05E-02"},"CDC42"]
["α-Adrenergic Signaling",{"v":0.923,"d":"9.23E-01"},{"v":0.0103,"d":"1.03E-02"},"GNAI2"]
["CDK5 Signaling",{"v":0.898,"d":"8.98E-01"},{"v":0.00971,"d":"9.71E-03"},"LAMC1"]
["HGF Signaling",{"v":0.879,"d":"8.79E-01"},{"v":0.00926,"d":"9.26E-03"},"CDC42"]
["Pancreatic Adenocarcinoma Signaling",{"v":0.879,"d":"8.79E-01"},{"v":0.00926,"d":"9.26E-03"},"CDC42"]
["phagosome formation",{"v":0.875,"d":"8.75E-01"},{"v":0.00917,"d":"9.17E-03"},"IGHG3"]
["Role of Tissue Factor in Cancer",{"v":0.864,"d":"8.64E-01"},{"v":0.00893,"d":"8.93E-03"},"CDC42"]
["Sphingosine-1-phosphate Signaling",{"v":0.861,"d":"8.61E-01"},{"v":0.00885,"d":"8.85E-03"},"GNAI2"]
["NGF Signaling",{"v":0.861,"d":"8.61E-01"},{"v":0.00885,"d":"8.85E-03"},"CDC42"]
["IL-6 Signaling",{"v":0.85,"d":"8.50E-01"},{"v":0.00862,"d":"8.62E-03"},"HSPB1"]
["p38 MAPK Signaling",{"v":0.847,"d":"8.47E-01"},{"v":0.00855,"d":"8.55E-03"},"HSPB1"]
["Gα12/13 Signaling",{"v":0.843,"d":"8.43E-01"},{"v":0.00847,"d":"8.47E-03"},"CDC42"]
["14-3-3-mediated Signaling",{"v":0.84,"d":"8.40E-01"},{"v":0.0084,"d":"8.40E-03"},"VIM"]
["HMGB1 Signaling",{"v":0.837,"d":"8.37E-01"},{"v":0.00833,"d":"8.33E-03"},"CDC42"]
["PTEN Signaling",{"v":0.837,"d":"8.37E-01"},{"v":0.00833,"d":"8.33E-03"},"CDC42"]
["CCR3 Signaling in Eosinophils",{"v":0.83,"d":"8.30E-01"},{"v":0.0082,"d":"8.20E-03"},"GNAI2"]
["Gαi Signaling",{"v":0.827,"d":"8.27E-01"},{"v":0.00813,"d":"8.13E-03"},"GNAI2"]
["p70S6K Signaling",{"v":0.82,"d":"8.20E-01"},"8E-03","GNAI2"]
["phagosome maturation",{"v":0.814,"d":"8.14E-01"},{"v":0.00787,"d":"7.87E-03"},"CALR"]
["P2Y Purigenic Receptor Signaling Pathway",{"v":0.808,"d":"8.08E-01"},{"v":0.00775,"d":"7.75E-03"},"GNAI2"]
["Hereditary Breast Cancer Signaling",{"v":0.801,"d":"8.01E-01"},{"v":0.00763,"d":"7.63E-03"},"ACTB"]
["Relaxin Signaling",{"v":0.761,"d":"7.61E-01"},{"v":0.0069,"d":"6.90E-03"},"GNAI2"]
["Synaptic Long Term Depression",{"v":0.745,"d":"7.45E-01"},{"v":0.00662,"d":"6.62E-03"},"GNAI2"]
["Glioblastoma Multiforme Signaling",{"v":0.745,"d":"7.45E-01"},{"v":0.00662,"d":"6.62E-03"},"CDC42"]
["CXCR4 Signaling",{"v":0.722,"d":"7.22E-01"},{"v":0.00625,"d":"6.25E-03"},"GNAI2"]
["Aldosterone Signaling in Epithelial Cells",{"v":0.718,"d":"7.18E-01"},{"v":0.00617,"d":"6.17E-03"},"HSPB1"]
["Dopamine-DARPP32 Feedback in cAMP Signaling",{"v":0.687,"d":"6.87E-01"},{"v":0.00571,"d":"5.71E-03"},"GNAI2"]
["Role of NFAT in Regulation of the Immune Response",{"v":0.683,"d":"6.83E-01"},{"v":0.00565,"d":"5.65E-03"},"GNAI2"]
["Dendritic Cell Maturation",{"v":0.681,"d":"6.81E-01"},{"v":0.00562,"d":"5.62E-03"},"IGHG3"]
["CREB Signaling in Neurons",{"v":0.679,"d":"6.79E-01"},{"v":0.00559,"d":"5.59E-03"},"GNAI2"]
["Role of NFAT in Cardiac Hypertrophy",{"v":0.664,"d":"6.64E-01"},{"v":0.00538,"d":"5.38E-03"},"GNAI2"]
["Calcium Signaling",{"v":0.664,"d":"6.64E-01"},{"v":0.00538,"d":"5.38E-03"},"CALR"]
["Endothelin-1 Signaling",{"v":0.662,"d":"6.62E-01"},{"v":0.00535,"d":"5.35E-03"},"GNAI2"]
["IL-8 Signaling",{"v":0.66,"d":"6.60E-01"},{"v":0.00532,"d":"5.32E-03"},"GNAI2"]
["ERK/MAPK Signaling",{"v":0.654,"d":"6.54E-01"},{"v":0.00524,"d":"5.24E-03"},"HSPB1"]
["AMPK Signaling",{"v":0.646,"d":"6.46E-01"},{"v":0.00513,"d":"5.13E-03"},"ACTB"]
["Thrombin Signaling",{"v":0.644,"d":"6.44E-01"},{"v":0.0051,"d":"5.10E-03"},"GNAI2"]
["Systemic Lupus Erythematosus Signaling",{"v":0.603,"d":"6.03E-01"},{"v":0.00459,"d":"4.59E-03"},"IGHG3"]
["cAMP-mediated signaling",{"v":0.595,"d":"5.95E-01"},{"v":0.00448,"d":"4.48E-03"},"GNAI2"]
["LPS/IL-1 Mediated Inhibition of RXR Function",{"v":0.59,"d":"5.90E-01"},{"v":0.00442,"d":"4.42E-03"},"GSTP1"]
["Phospholipase C Signaling",{"v":0.56,"d":"5.60E-01"},{"v":0.00408,"d":"4.08E-03"},"IGHG3"]
["G-Protein Coupled Receptor Signaling",{"v":0.532,"d":"5.32E-01"},{"v":0.00379,"d":"3.79E-03"},"GNAI2"]
["Xenobiotic Metabolism Signaling",{"v":0.516,"d":"5.16E-01"},{"v":0.00362,"d":"3.62E-03"},"GSTP1"]
["Glucocorticoid Receptor Signaling",{"v":0.51,"d":"5.10E-01"},{"v":0.00356,"d":"3.56E-03"},"ACTB"]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",{"v":0.484,"d":"4.84E-01"},{"v":0.00331,"d":"3.31E-03"},"IGHG3"]
["Protein Kinase A Signaling",{"v":0.389,"d":"3.89E-01"},{"v":0.00251,"d":"2.51E-03"},"GNAI2"]

{"sheet":"Functions and disease","index":1,"n_rows":74,"n_cols":3,"rows_kept":74,"flags":["formulas_cached_only"]}
["© 2000-2016 QIAGEN. All rights reserved."]
["Category"," p-value","Molecules"]
["Organismal Injury and Abnormalities","4.24E-09-1.01E-02","LAMC1,SERPINB9,ACTR3,IGHG3,COMT,ANXA5,PGAM1,KRT1,CPNE1,KRT10,ACTR2,CALR,PSMA6,IGKC,ACTB,VIM,PSMA1,GNAI2,ALB,HNRNPH1,CDC42,ARPC2,HPRT1,ACTG1,HADH,GSTP1,RBP4,HSPB1"]
["Cell Death and Survival","2.51E-07-9.75E-03","CALR,PSMA6,IGKC,ACTB,VIM,PSMA1,LAMC1,GNAI2,SERPINB9,ALB,IGHG3,HNRNPH1,CDC42,COMT,ANXA5,HPRT1,GSTP1,KRT10,RBP4,HSPB1"]
["Inflammatory Response","1.52E-06-1.04E-02","CALR,ACTB,IGKC,VIM,GNAI2,ALB,SERPINB9,IGHG3,CDC42,ANXA5,HPRT1,KRT1,ACTG1,CPNE1,GSTP1,KRT10,HSPB1,RBP4"]
["Connective Tissue Disorders","1.65E-06-6.03E-03","GNAI2,CALR,ALB,IGKC,ACTB,VIM,HPRT1,ACTG1,GSTP1,RBP4"]
["Developmental Disorder","1.65E-06-1.04E-02","CALR,IGKC,ACTB,VIM,GNAI2,LAMC1,ALB,HPRT1,KRT1,ACTG1,KRT10,HADH,RBP4"]
["Skeletal and Muscular Disorders","1.65E-06-9.12E-03","GNAI2,CALR,ALB,ACTB,COMT,IGKC,VIM,HPRT1,ACTG1,HADH,GSTP1,RBP4,HSPB1"]
["Cellular Assembly and Organization","4.22E-06-1.04E-02","CALR,ACTR2,ACTB,VIM,GNAI2,LAMC1,ALB,IGHG3,ACTR3,CDC42,ANXA5,ARPC2,COMT,HPRT1,KRT1,ACTG1,HSPB1"]
["Cellular Function and Maintenance","4.22E-06-1.04E-02","ACTR2,CALR,IGKC,ACTB,VIM,LAMC1,GNAI2,ACTR3,CDC42,COMT,ANXA5,ARPC2,HPRT1,ACTG1,HSPB1"]
["Tissue Development","4.44E-06-1.04E-02","ACTR2,CALR,IGKC,ACTB,VIM,LAMC1,GNAI2,ALB,ACTR3,CDC42,ANXA5,COMT,ARPC2,HPRT1,ACTG1,CPNE1,GSTP1,KRT10,HSPB1,RBP4"]
["Inflammatory Disease","4.65E-06-9.12E-03","CALR,IGKC,ACTB,VIM,GNAI2,ALB,ANXA5,HPRT1,KRT1,CPNE1,GSTP1,KRT10,RBP4"]
["Immunological Disease","6.21E-06-9.12E-03","CALR,IGKC,ACTB,VIM,ALB,COMT,ANXA5,HPRT1,KRT1,ACTG1,CPNE1,KRT10,GSTP1,RBP4,HSPB1"]
["Cell Morphology","2.54E-05-1.04E-02","CALR,ACTR2,ACTB,IGKC,VIM,LAMC1,SERPINB9,ALB,ACTR3,CDC42,ARPC2,ANXA5,HPRT1,KRT1,HADH,RBP4,HSPB1"]
["Cellular Development","2.54E-05-9.12E-03","CALR,IGKC,ACTB,VIM,LAMC1,GNAI2,SERPINB9,ALB,ACTR3,CDC42,HPRT1,ACTG1,CPNE1,GSTP1,HSPB1"]
["Cellular Growth and Proliferation","2.54E-05-9.12E-03","CALR,ACTB,IGKC,VIM,LAMC1,GNAI2,SERPINB9,ALB,ACTR3,CDC42,COMT,HPRT1,ACTG1,KRT10,GSTP1,HSPB1,RBP4"]
["Cell-To-Cell Signaling and Interaction","2.82E-05-9.71E-03","ACTR2,CALR,IGKC,ACTB,VIM,GNAI2,LAMC1,ALB,SERPINB9,IGHG3,CDC42,ARPC2,ANXA5,COMT,HPRT1,ACTG1,HSPB1,RBP4"]
["Cellular Movement","3.45E-05-1.04E-02","ACTR2,CALR,ACTB,VIM,GNAI2,LAMC1,ALB,ACTR3,CDC42,ARPC2,ANXA5,KRT10,HSPB1"]
["Connective Tissue Development and Function","3.45E-05-1.04E-02","LAMC1,GNAI2,CALR,ACTR2,ACTR3,CDC42,COMT,ARPC2,VIM"]
["Lipid Metabolism","4.38E-05-1.04E-02","GNAI2,ALB,CDC42,ANXA5,COMT,VIM,GSTP1,RBP4"]
["Molecular Transport","4.38E-05-1.04E-02","GNAI2,CALR,ALB,CDC42,COMT,VIM,GSTP1,RBP4"]
["Small Molecule Biochemistry","4.38E-05-1.04E-02","GNAI2,CALR,ALB,CDC42,ANXA5,COMT,VIM,HPRT1,KRT1,HADH,GALM,GSTP1,RBP4"]
["Embryonic Development","4.4E-05-1.04E-02","LAMC1,CALR,ACTR3,CDC42,ANXA5,COMT,VIM,ACTG1,RBP4"]
["Organ Development","4.4E-05-9.12E-03","CALR,ALB,CDC42,ANXA5,VIM,HPRT1,ACTG1,RBP4"]
["Organismal Development","4.4E-05-1.04E-02","CALR,IGKC,ACTB,VIM,GNAI2,LAMC1,CDC42,ANXA5,COMT,KRT1,ACTG1,HADH,KRT10,HSPB1,RBP4"]
["Skeletal and Muscular System Development and Function","4.4E-05-1.04E-02","GNAI2,CALR,CDC42,ANXA5,COMT,VIM,ACTG1,RBP4"]
["Psychological Disorders","5.8E-05-9.79E-03","ALB,ACTB,COMT,VIM,HADH,GSTP1,RBP4,HSPB1"]
["Infectious Diseases","1.08E-04-1.04E-02","ACTR2,SERPINB9,ALB,ACTR3,HNRNPH1,CDC42,IGKC,ANXA5,ACTB,PSMA1"]
["Cell Signaling","1.27E-04-9.12E-03","GNAI2,CALR,CDC42,CPNE1,GSTP1,HSPB1"]
["DNA Replication, Recombination, and Repair","1.27E-04-9.12E-03","GNAI2,CALR,CDC42,IGKC,VIM,GSTP1,HSPB1"]
["Nucleic Acid Metabolism","1.27E-04-9.12E-03","GNAI2,CALR,CDC42,HPRT1"]
["Immune Cell Trafficking","2.14E-04-1.04E-02","GNAI2,CALR,SERPINB9,ALB,IGHG3,CDC42,ACTB,ANXA5,HPRT1,KRT10,RBP4,HSPB1"]
["Cell Cycle","2.49E-04-5.22E-03","GNAI2,ACTR2,ACTR3,CDC42,VIM"]
["Renal and Urological Disease","2.61E-04-9.12E-03","CALR,ACTB,LAMC1,ALB,HNRNPH1,CDC42,COMT,ARPC2,ANXA5,HPRT1,GSTP1,HSPB1,RBP4"]
["Hematological Disease","4.14E-04-9.12E-03","CALR,IGKC,ACTB,VIM,GNAI2,ALB,COMT,ANXA5,HPRT1,KRT1,ACTG1,HADH,GSTP1,KRT10,CPNE1,HSPB1"]
["Amino Acid Metabolism","4.86E-04-7.82E-03","ALB,COMT,HADH"]
["Energy Production","4.86E-04-1.31E-03","ALB,HADH"]
["Post-Translational Modification","4.86E-04-1.04E-02","GNAI2,CALR,ALB,CDC42,GSTP1,HADH,HSPB1"]
["Cell-mediated Immune Response","7.78E-04-9.55E-03","GNAI2,CALR,CDC42,ACTB,IGKC"]
["Free Radical Scavenging","9.52E-04-3.85E-03","ALB,CDC42,ACTB,GSTP1,HSPB1"]
["Drug Metabolism","1.01E-03-9.12E-03","ALB,COMT,HPRT1,GSTP1"]
["Gastrointestinal Disease","1.01E-03-1E-02","CALR,VIM,PSMA1,GNAI2,ALB,IGHG3,HNRNPH1,CDC42,ANXA5,HPRT1,KRT10,HADH,GSTP1,HSPB1,RBP4"]
["Cardiovascular Disease","1.07E-03-6.52E-03","LAMC1,GNAI2,CALR,ALB,PSMA6,ANXA5,VIM,HPRT1,GSTP1,RBP4,HSPB1"]
["Respiratory Disease","1.07E-03-2.52E-03","GNAI2,ALB,COMT,ACTB"]
["Behavior","1.31E-03-8.74E-03","GNAI2,COMT,HPRT1"]
["Carbohydrate Metabolism","1.31E-03-9.23E-03","CALR,ALB,ANXA5,GALM"]
["Cardiovascular System Development and Function","1.31E-03-1.04E-02","LAMC1,CALR,CDC42,ANXA5,VIM,KRT1,ACTG1,HSPB1"]
["Cellular Compromise","1.31E-03-9.12E-03","IGHG3,CDC42,ANXA5,PGAM1,VIM"]
["Endocrine System Development and Function","1.31E-03-9.12E-03","COMT,GSTP1"]
["Hepatic System Disease","1.31E-03-9.12E-03","ALB,VIM,HPRT1,GSTP1"]
["Metabolic Disease","1.31E-03-1E-02","GNAI2,ALB,CDC42,COMT,ANXA5,VIM,HPRT1,PSMA1,GSTP1,HADH,RBP4,HSPB1"]
["Organ Morphology","1.31E-03-1.04E-02","LAMC1,COMT,KRT1"]
["Organismal Survival","1.31E-03-1.31E-03","GSTP1"]
["RNA Post-Transcriptional Modification","1.31E-03-2.61E-03","HPRT1"]
["Tissue Morphology","1.31E-03-9.12E-03","LAMC1,GNAI2,CDC42,IGKC,VIM"]
["Tumor Morphology","1.31E-03-1.31E-03","VIM"]
["Protein Synthesis","2.02E-03-5.22E-03","CDC42,ANXA5,ARPC2,HPRT1"]
["Reproductive System Development and Function","2.1E-03-9.12E-03","LAMC1,CALR,CDC42,ANXA5,COMT"]
["Cellular Response to Therapeutics","2.61E-03-2.61E-03","ACTG1"]
["Digestive System Development and Function","2.61E-03-9.12E-03","ALB,CDC42,VIM,HPRT1"]
["Hematopoiesis","2.61E-03-9.12E-03","IGKC"]
["Humoral Immune Response","2.61E-03-1.04E-02","GNAI2,IGKC"]
["Respiratory System Development and Function","3.92E-03-3.92E-03","CDC42"]
["Vitamin and Mineral Metabolism","3.92E-03-1.04E-02","CALR,COMT,KRT1,RBP4"]
["Protein Trafficking","5.22E-03-5.22E-03","CDC42"]
["Organismal Functions","6.52E-03-6.52E-03","VIM"]
["RNA Trafficking","6.52E-03-6.52E-03","ALB"]
["Protein Folding","6.56E-03-1.04E-02","CALR,HSPB1"]
["Gene Expression","7.82E-03-7.82E-03","ALB"]
["Hepatic System Development and Function","7.82E-03-9.12E-03","ALB,HPRT1"]
["Renal and Urological System Development and Function","8.76E-03-9.12E-03","LAMC1,CDC42,COMT,RBP4"]
["Lymphoid Tissue Structure and Development","9.12E-03-1.04E-02","GNAI2,IGKC"]
["Nutritional Disease","9.12E-03-9.12E-03","ALB"]
["Hair and Skin Development and Function","1.04E-02-1.04E-02","KRT1"]

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{"sheet":"Tox functions","index":3,"n_rows":0,"n_cols":0,"rows_kept":0,"hidden":true,"flags":["formulas_cached_only"]}

{"sheet":"Networks","index":4,"n_rows":0,"n_cols":0,"rows_kept":0,"hidden":true,"flags":["formulas_cached_only"]}