SLCO1B1 *Diplotype Coded Diplotype/Phenotype Summary Total Diplotype Count Number of screenee SA Diplotype MAF AMFC MAF AMR MAF CSA MAF EAS MAF EUR MAF NEA MAF SSA MAF QAR MAF MAF SA/ MA FAMFC MAF SA/ MAF AMR MAF SA/ MAF CMAF MAF SA/ MAF EAS MAF SA/ MAF EUR MAF SA/ MAF NEA MAF SA/ MAF SSA MAF SA/MAF QAR SA/AMFC p-value SA/ AMR p-value SA/ CSA p-value SA/EAS p-value SA/EUR p-value SA/NEA p-value SA/SSA p-value SA/ QAR p-value *1/*1 Normal Function 348 1928 0.180498 0.052900 0.136900 0.220637 0.065139 0.162207 0.240100 0.029345 3.412058 1.318465 0.818076 2.770983 1.112761 0.751761 6.150919 0.050408749 0.319777212 1.64953E-05 1.67144E-64 0.035483147 0.091329299 1.35284E-24 *1/*5 Decreased Function 71 1928 0.036826 0 0 0.004200 0.000511 0.016436 0.049000 0 0.026271 8.767231 72.121354 2.240598 0.751545 1.401753 0.643978203 0.168717012 3.20989E-38 4.60985E-94 2.75467E-09 0.661597557 9.85341E-09 0.154933368 *1/*14 Normal Function 106 1928 0.054979 0.109202 0 0.503462 1.20499E-16 5.26183E-13 *1/*15 Decreased Function 411 1928 0.213174 0.004600 0.177600 0.061224 0.063569 0.120964 0.147000 0.009571 0.134746 46.342233 1.200306 3.481876 3.353448 1.762292 1.450165 22.273993 1.582048 0.000178443 0.533872821 4.9922E-103 1.7299E-101 1.23566E-29 0.033831578 3.20647E-44 1.41125E-07 *1/*19 Indeterminate Function 8 1928 0.004149 *1/*20 Normal Function 140 1928 0.072614 0.030120 2.410840 4.35062E-20 *1/*28 Indeterminate Function 1 1928 0.000519 *1/*30 Indeterminate Function 2 1928 0.001037 *1/*31 Decreased Function 4 1928 0.002075 0.002542 0.816044 1 *1/*37 Normal Function 192 1928 0.099585 0.349600 0.288600 0.432366 0.313790 0.203580 0.303800 0.274347 0.284854 0.345063 0.230326 0.317362 0.489169 0.327798 0.362990 6.03E-05 5.49E-05 9.6289E-222 3.277E-110 1.4389E-34 1.22133E-11 2.01997E-23 *1/*41 Indeterminate Function 4 1928 0.002075 0 0 0.000081 25.756561 8.45139E-07 7.78198E-09 2.40718E-05 *4/*37 Indeterminate Function 5 1928 0.002593 *5/*5 Poor Function 5 1928 0.002593 0 0 0.000020 0.000001 0.000416 0.002500 0 129.725019 2591.710077 6.229000 1.037344 1 1 4.12332E-06 7.78198E-09 0.009293938 1 0.579406701 *5/*14 Decreased Function 7 1928 0.003631 0.005532 0 0 0.656254 0.214224603 0.346700491 0.10060834 *5/*15 Poor Function 36 1928 0.018672 0 0 0.000583 0.000249 0.006128 0.015000 0 0.010169 32.040081 74.943364 3.046852 1.244813 1.836100 1 0.628333291 1.2986E-35 1.06002E-49 1.08227E-08 0.764542342 9.46625E-05 0.084466557 *5/*19 Indeterminate Function 1 1928 0.000519 *5/*20 Decreased Function 1 1928 0.000519 0.001526 0 0.339902 0.129808608 *5/*31 Poor Function 1 1928 0.000519 *5/*37 Decreased Function 20 1928 0.010373 0 0 0.004116 0.001230 0.010314 0.031000 0 0.008475 2.520524 8.434602 1.005775 0.334627 1.22406639 1 1 0.00029256 2.25812E-12 0.910146478 0.039232615 0.007024328 0.689543096 *5/*41 Indeterminate Function 1 1928 0.000519 0 0 0.000004 127.098562 1 *9/*20 Decreased Function 1 1928 0.000519 0 *14/*14 Increased Function 8 1928 0.004149 0.018379 0 0.225761 5.59141E-08 0.210729171 *14/*15 Decreased Function 51 1928 0.026452 0.040718 0 0 0.649643 0.000638026 3.42059E-06 8.39099E-10 *14/*19 Indeterminate Function 1 1928 0.000519 *14/*20 Increased Function 16 1928 0.008299 0.010139 0.818519 0.361457078 *14/*31 Decreased Function 1 1928 0.000519 0 *14/*37 Normal Function 35 1928 0.018154 0.068528 0 0.264908 1.60237E-24 0.000150808 *15/*15 Poor Function 141 1928 0.073133 0.000100 0.057600 0.004247 0.015509 0.022552 0.022500 0.000780 0.022034 731.327801 1.269666 17.218988 4.715460 3.242862 3.250346 93.719687 3.319103 0.107613 0.622251151 1.864E-108 2.14661E-49 1.01866E-32 0.005343154 3.77795E-17 9.0244E-10 *15/*19 Indeterminate Function 4 1928 0.002075 *15/*20 Decreased Function 67 1928 0.034751 0.011231 0 3.094272 9.97867E-15 1.23564E-12 *15/*37 Decreased Function 99 1928 0.051349 0.015200 0.187200 0.059988 0.153114 0.075909 0.093000 0.044738 0.048305 3.378194 0.274298 0.855980 0.335362 0.676452 0.552135 1.147768 1.063005 0.258049 0.000507879 0.097022273 4.29904E-45 1.57679E-05 0.029995464 0.511058711 0.788540087 *15/*41 Indeterminate Function 4 1928 0.002075 0 0 0.000030 69.076636 8.45139E-07 7.78198E-09 6.33112E-07 *19/*19 Indeterminate Function 2 1928 0.001037 *19/*37 Indeterminate Function 2 1928 0.001037 *20/*20 Increased Function 18 1928 0.009336 0.001398 6.677140 7.2488E-10 *20/*31 Decreased Function 1 1928 0.000519 0 *20/*37 Normal Function 47 1928 0.024378 0.018901 1.289744 0.111415273 *20/*41 Indeterminate Function 1 1928 0.000519 0.000007 69.354638 1 *31/*37 Decreased Function 1 1928 0.000519 0.004237 0.013731215 *37/*37 Normal Function 61 1928 0.031639 0.577600 0.152100 0.211819 0.377903 0.063876 0.096100 0.641220 0.054777 0.208015 0.149368 0.083723 0.495317 0.329230 0.049342 0.122406639 1.22109E-20 0.00028441 9.6265E-116 7.4291E-293 3.20396E-10 0.000499332 5.1337E-220 *37/*41 Indeterminate Function 3 1928 0.001556 0 0 0.000051 30.783253 0.00092024 8.83063E-05 0.004730007 AMFC African American/ Afro-Caribbean AMR American CSA Central/South Asian EAS East Asian EUR European NEA Near Eastern SSA Sub-Saharan African QAR Qatari